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TCF4_ENST00000564999 ,TCF4 ,P15884
  • Uniprot Accession= P15884
  • Ensembl Transcript= ENST00000564999.5
  • Uniprot Name= TCF4
  • Name= Transcription factor 4
  • Chromosome= chr18
  • Driver status= Compendium
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 34
  • Number of Interaction partner in hippie: 299
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABI1 ABI1 Q8IZP0 Abl interactor 1 chr10 Census, Compendium Yes 1 hippie 55 360 39 39 0
ABI2_ENST00000261018 ABI2 Q9NYB9 Abl interactor 2 chr2 Not Cancer Driver No 1 hippie 56 361 38 38 0
ACTL6A ACTL6A O96019 Actin-like protein 6A chr3 Not Cancer Driver No 1 hippie 61 74 15 15 0
ALKBH4 ALKBH4 Q9NXW9 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 chr7 Not Cancer Driver No 1 hippie 39 14 2 2 0
ANAPC1 ANAPC1 Q9H1A4 Anaphase-promoting complex subunit 1 chr2 Not Cancer Driver No 1 hippie 206 263 33 33 0
APBB1 APBB1 O00213 Amyloid beta precursor protein binding family B member 1 chr11 Not Cancer Driver No 1 hippie 105 399 58 58 0
AQP1 AQP1 P29972 Aquaporin-1 chr7 Not Cancer Driver No 1 hippie 39 4 1 1 0
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 196 443 88 88 169
ARFGAP2 ARFGAP2 Q8N6H7 ADP-ribosylation factor GTPase-activating protein 2 chr11 Not Cancer Driver No 2 hippie, biogrid 62 345 40 40 0
ARHGEF1_ENST00000354532 ARHGEF1 Q92888 Rho guanine nucleotide exchange factor 1 chr19 Not Cancer Driver No 1 hippie 127 457 67 67 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 Not Cancer Driver No 1 hippie 170 1141 127 127 0
ARL16 ARL16 Q0P5N6 ADP-ribosylation factor-like protein 16 chr17 Not Cancer Driver No 1 hippie 26 29 7 7 0
ARMC7 ARMC7 Q9H6L4 Armadillo repeat-containing protein 7 chr17 Not Cancer Driver No 1 hippie 22 26 3 3 0
ARMC8_ENST00000469044 ARMC8 Q8IUR7 Armadillo repeat-containing protein 8 chr3 Not Cancer Driver No 1 hippie 71 7 0 0 0
ASAP3 ASAP3 Q8TDY4 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 chr1 Not Cancer Driver No 1 hippie 99 389 48 48 0
ASCL1 ASCL1 P50553 Achaete-scute homolog 1 chr12 Not Cancer Driver No 2 hippie, biogrid 33 182 24 24 0
ASCL3 ASCL3 Q9NQ33 Achaete-scute homolog 3 chr11 Not Cancer Driver No 2 hippie, biogrid 19 67 10 10 0
ASCL4 ASCL4 Q6XD76 Achaete-scute homolog 4 chr12 Not Cancer Driver No 1 hippie 25 78 15 15 0
ASPSCR1_ENST00000306739 ASPSCR1 Q9BZE9 Tether containing UBX domain for GLUT4 chr17 Census Yes 1 hippie 72 298 49 49 0
ATG9A ATG9A Q7Z3C6 Autophagy-related protein 9A chr2 Not Cancer Driver No 1 hippie 92 252 30 30 0
ATOH7 ATOH7 Q8N100 Transcription factor ATOH7 chr10 Not Cancer Driver No 1 hippie 10 40 3 3 2
ATP11B ATP11B Q9Y2G3 Phospholipid-transporting ATPase IF chr3 Not Cancer Driver No 1 hippie 129 73 10 10 0
ATP6V1B2 ATP6V1B2 P21281 V-type proton ATPase subunit B, brain isoform chr8 Not Cancer Driver No 1 hippie 63 49 4 4 1
BACH1_ENST00000286800 BACH1 O14867 Transcription regulator protein BACH1 chr21 Not Cancer Driver No 1 hippie 105 328 39 39 0
BANF2_ENST00000377805 BANF2 Q9H503 Barrier-to-autointegration factor-like protein chr20 Not Cancer Driver No 1 hippie 11 0 0 0 0
BCAS2 BCAS2 O75934 Pre-mRNA-splicing factor SPF27 chr1 Not Cancer Driver No 1 hippie 30 55 5 5 0
BCL2L15 BCL2L15 Q5TBC7 Bcl-2-like protein 15 chr1 Not Cancer Driver No 1 hippie 23 5 0 0 0
BCL2L2 BCL2L2 Q92843 Bcl-2-like protein 2 chr14 Not Cancer Driver No 1 hippie 22 34 6 6 0
BCL9 BCL9 O00512 B-cell CLL/lymphoma 9 protein chr1 Census, Compendium Yes 1 hippie 219 1426 219 219 0
BHLHA15 BHLHA15 Q7RTS1 Class A basic helix-loop-helix protein 15 chr7 Not Cancer Driver No 1 hippie 12 183 12 12 0
C1orf109 C1orf109 Q9NX04 Uncharacterized protein C1orf109 chr1 Not Cancer Driver No 1 hippie 17 0 0 0 0
C1orf50 C1orf50 Q9BV19 Uncharacterized protein C1orf50 chr1 Not Cancer Driver No 1 hippie 24 66 5 5 0
CA9 CA9 Q16790 Carbonic anhydrase 9 chr9 Not Cancer Driver No 1 hippie 72 274 50 50 0
CABP5 CABP5 Q9NP86 Calcium-binding protein 5 chr19 Not Cancer Driver No 1 hippie 44 32 4 4 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 Not Cancer Driver No 1 hippie 19 115 15 15 7
CBFA2T2 CBFA2T2 O43439 Protein CBFA2T2 chr20 Not Cancer Driver No 1 hippie 89 457 58 58 0
CBFA2T3 CBFA2T3 O75081 Protein CBFA2T3 chr16 Census, Compendium Yes 3 hippie, biogrid 83 502 70 70 0
CCNH CCNH P51946 Cyclin-H chr5 Not Cancer Driver No 1 hippie 40 28 4 4 0
CD47 CD47 Q08722 Leukocyte surface antigen CD47 chr3 Not Cancer Driver No 1 hippie 37 0 0 0 0
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 1 hippie 52 214 31 31 0
CDC73 CDC73 Q6P1J9 Parafibromin chr1 Census, Compendium Yes 1 hippie 110 210 39 39 2
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 Census, Compendium Yes 1 hippie 48 121 30 30 0
CDKN2C_ENST00000371761 CDKN2C P42773 Cyclin-dependent kinase 4 inhibitor C chr1 Census, Compendium Yes 1 hippie 23 49 6 6 0
CFAP77 CFAP77 Q6ZQR2 Cilia- and flagella-associated protein 77 chr9 Not Cancer Driver No 1 hippie 83 168 45 45 0
CHAF1A CHAF1A Q13111 Chromatin assembly factor 1 subunit A chr19 Not Cancer Driver No 1 hippie 133 767 99 99 0
CHCHD2 CHCHD2 Q9Y6H1 Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 chr7 Not Cancer Driver No 1 hippie 24 114 21 21 1
CHIC2 CHIC2 Q9UKJ5 Cysteine-rich hydrophobic domain-containing protein 2 chr4 Census Yes 1 hippie 17 6 0 0 0
CKS1B CKS1B P61024 Cyclin-dependent kinases regulatory subunit 1 chr1 Not Cancer Driver No 1 hippie 10 10 0 0 0
CLCNKA CLCNKA P51800 Chloride channel protein ClC-Ka chr1 Not Cancer Driver No 1 hippie 92 35 3 3 1
CMTR1 CMTR1 Q8N1G2 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 chr6 Not Cancer Driver No 1 hippie 81 176 20 20 0
COA5 COA5 Q86WW8 Cytochrome c oxidase assembly factor 5 chr2 Not Cancer Driver No 1 hippie 10 2 0 0 1
CPNE2_ENST00000535318 CPNE2 Q96FN4 Copine-2 chr16 Not Cancer Driver No 1 hippie 62 32 4 4 0
CPOX CPOX P36551 Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial chr3 Not Cancer Driver No 1 hippie 49 126 7 7 17
CPS1_ENST00000233072 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 Not Cancer Driver No 1 hippie 368 73 22 22 140
CTBP1 CTBP1 Q13363 C-terminal-binding protein 1 chr4 Not Cancer Driver No 1 hippie 42 123 9 9 1
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
CUL4B CUL4B Q13620 Cullin-4B chrX Not Cancer Driver No 1 hippie 138 207 38 38 2
CYFIP2 CYFIP2 Q96F07 Cytoplasmic FMR1-interacting protein 2 chr5 Not Cancer Driver No 1 hippie 211 86 11 11 3
DAXX_ENST00000266000 DAXX Q9UER7 Death domain-associated protein 6 chr6 Census, Compendium Yes 1 hippie 106 549 81 81 0
DCAF13_ENST00000612750 DCAF13 Q9NV06 DDB1- and CUL4-associated factor 13 chr8 Not Cancer Driver No 1 hippie 85 101 18 18 0
DDX6 DDX6 P26196 Probable ATP-dependent RNA helicase DDX6 chr11 Census, Compendium Yes 1 hippie 44 129 7 7 5
DEF6 DEF6 Q9H4E7 Differentially expressed in FDCP 6 homolog chr6 Not Cancer Driver No 1 hippie 72 336 30 30 0
DGCR6 DGCR6 Q14129 Protein DGCR6 chr22 Not Cancer Driver No 1 hippie 27 60 9 9 0
DMRT3 DMRT3 Q9NQL9 Doublesex- and mab-3-related transcription factor 3 chr9 Not Cancer Driver No 1 hippie 94 345 71 71 0
DNTT DNTT P04053 DNA nucleotidylexotransferase chr10 Not Cancer Driver No 1 hippie 106 66 16 16 0
DOT1L DOT1L Q8TEK3 Histone-lysine N-methyltransferase, H3 lysine-79 specific chr19 Compendium Yes 1 hippie 178 988 118 118 0
DUSP23_ENST00000368109 DUSP23 Q9BVJ7 Dual specificity protein phosphatase 23 chr1 Not Cancer Driver No 1 hippie 6 13 1 1 0
EFHC1 EFHC1 Q5JVL4 EF-hand domain-containing protein 1 chr6 Not Cancer Driver No 1 hippie 79 78 15 15 17
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EGR1 EGR1 P18146 Early growth response protein 1 chr5 Not Cancer Driver No 1 hippie 78 501 72 72 0
EIF4E2 EIF4E2 O60573 Eukaryotic translation initiation factor 4E type 2 chr2 Not Cancer Driver No 1 hippie 27 80 5 5 0
EIF4EBP1 EIF4EBP1 Q13541 Eukaryotic translation initiation factor 4E-binding protein 1 chr8 Not Cancer Driver No 1 hippie 8 118 8 8 0
EMG1 EMG1 Q92979 Ribosomal RNA small subunit methyltransferase NEP1 chr12 Not Cancer Driver No 1 hippie, biogrid 28 58 4 4 1
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
EPB41L3 EPB41L3 Q9Y2J2 Band 4.1-like protein 3 chr18 Not Cancer Driver No 1 hippie 298 695 207 207 0
EPHB6_ENST00000422643 EPHB6 O15197 Ephrin type-B receptor 6 chr7 Not Cancer Driver No 1 hippie 227 246 45 45 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 1 hippie 275 314 41 41 1
ETS1_ENST00000319397 ETS1 P14921 Protein C-ets-1 chr11 Not Cancer Driver No 1 hippie 68 78 9 9 0
EXOC8 EXOC8 Q8IYI6 Exocyst complex component 8 chr1 Not Cancer Driver No 1 hippie 84 195 21 21 0
EXOSC1 EXOSC1 Q9Y3B2 Exosome complex component CSL4 chr10 Not Cancer Driver No 1 hippie 14 14 2 2 1
FAH_ENST00000561421 FAH P16930 Fumarylacetoacetase chr15 Not Cancer Driver No 1 hippie 50 41 10 10 20
FAM110A_ENST00000246100 FAM110A Q9BQ89 Protein FAM110A chr20 Not Cancer Driver No 1 hippie 20 244 12 12 0
FAM124B FAM124B Q9H5Z6 Protein FAM124B chr2 Not Cancer Driver No 1 hippie 68 194 10 10 0
FERD3L FERD3L Q96RJ6 Fer3-like protein chr7 Not Cancer Driver No 3 hippie, biogrid 79 59 23 23 0
FIGLA FIGLA Q6QHK4 Factor in the germline alpha chr2 Not Cancer Driver No 2 hippie, biogrid 22 154 17 17 0
FLAD1 FLAD1 Q8NFF5 FAD synthase chr1 Not Cancer Driver No 1 hippie 81 59 6 6 1
FLNA FLNA P21333 Filamin-A chrX Census Yes 1 hippie 416 1456 214 214 28
FRS3_ENST00000259748 FRS3 O43559 Fibroblast growth factor receptor substrate 3 chr6 Not Cancer Driver No 1 hippie 77 388 58 58 0
FUS FUS P35637 RNA-binding protein FUS chr16 Census Yes 1 hippie 51 524 51 51 20
GEM GEM P55040 GTP-binding protein GEM chr8 Not Cancer Driver No 1 hippie 64 96 22 22 0
GLRX3 GLRX3 O76003 Glutaredoxin-3 chr10 Not Cancer Driver No 1 hippie 52 24 4 4 0
GNG10 GNG10 P50151 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 chr9 Not Cancer Driver No 1 hippie 5 0 0 0 0
GOPC GOPC Q9HD26 Golgi-associated PDZ and coiled-coil motif-containing protein chr6 Census Yes 1 hippie 56 263 34 34 0
GORASP2 GORASP2 Q9H8Y8 Golgi reassembly-stacking protein 2 chr2 Not Cancer Driver No 1 hippie 55 287 31 31 0
GPHN_ENST00000315266 GPHN Q9NQX3 Gephyrin chr14 Census Yes 1 hippie 126 305 41 41 2
GSE1 GSE1 Q14687 Genetic suppressor element 1 chr16 Not Cancer Driver No 3 hippie, biogrid 115 1133 110 110 0
GTF3C5_ENST00000372097 GTF3C5 Q9Y5Q8 General transcription factor 3C polypeptide 5 chr9 Not Cancer Driver No 1 hippie 75 157 21 21 0
GUCD1_ENST00000407471 GUCD1 Q96NT3 Protein GUCD1 chr22 Not Cancer Driver No 1 hippie 26 11 0 0 0
HAND1 HAND1 O96004 Heart- and neural crest derivatives-expressed protein 1 chr5 Not Cancer Driver No 1 hippie 35 166 29 29 0
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 Not Cancer Driver No 2 hippie, biogrid 47 124 29 29 0
HAT1 HAT1 O14929 Histone acetyltransferase type B catalytic subunit chr2 Not Cancer Driver No 1 hippie 51 14 2 2 0
HBP1_ENST00000468410 HBP1 O60381 HMG box-containing protein 1 chr7 Not Cancer Driver No 1 hippie 48 263 16 16 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 hippie 46 145 14 14 0
HEXIM2_ENST00000592695 HEXIM2 Q96MH2 Protein HEXIM2 chr17 Not Cancer Driver No 3 hippie, biogrid 35 286 35 35 0
HIC1 HIC1 Q14526 Hypermethylated in cancer 1 protein chr17 Not Cancer Driver No 1 hippie 24 361 6 6 0
HMG20A HMG20A Q9NP66 High mobility group protein 20A chr15 Not Cancer Driver No 2 hippie, biogrid 58 308 44 44 0
HNRNPC_ENST00000420743 HNRNPC P07910 Heterogeneous nuclear ribonucleoproteins C1/C2 chr14 Not Cancer Driver No 1 hippie 42 227 35 35 0
HSD17B8 HSD17B8 Q92506 (3R)-3-hydroxyacyl-CoA dehydrogenase chr6 Not Cancer Driver No 1 hippie 20 26 1 1 0
HSPB7 HSPB7 Q9UBY9 Heat shock protein beta-7 chr1 Not Cancer Driver No 1 hippie 21 153 19 19 0
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 Not Cancer Driver No 3 hippie, biogrid 20 17 6 6 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 Not Cancer Driver No 3 hippie, biogrid 14 52 7 7 0
ID3 ID3 Q02535 DNA-binding protein inhibitor ID-3 chr1 Census, Compendium Yes 3 hippie, biogrid 14 34 4 4 0
ID4 ID4 P47928 DNA-binding protein inhibitor ID-4 chr6 Not Cancer Driver No 2 hippie, biogrid 4 71 1 1 0
INS INS P01308 Insulin chr11 Not Cancer Driver No 1 hippie 15 5 1 1 22
IRF2BP2 IRF2BP2 Q7Z5L9 Interferon regulatory factor 2-binding protein 2 chr1 Not Cancer Driver No 1 hippie 42 451 26 26 1
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
JUP JUP P14923 Junction plakoglobin chr17 Not Cancer Driver No 1 hippie 112 241 37 37 0
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 Not Cancer Driver No 1 hippie 65 173 21 21 3
KCTD14 KCTD14 Q9BQ13 BTB/POZ domain-containing protein KCTD14 chr11 Not Cancer Driver No 1 hippie 45 37 3 3 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 Not Cancer Driver No 1 hippie 67 291 28 28 3
KLC3 KLC3 Q6P597 Kinesin light chain 3 chr19 Not Cancer Driver No 1 hippie 52 338 32 32 0
KLHL32 KLHL32 Q96NJ5 Kelch-like protein 32 chr6 Not Cancer Driver No 1 hippie 105 0 0 0 0
KLHL38 KLHL38 Q2WGJ6 Kelch-like protein 38 chr8 Not Cancer Driver No 1 hippie 114 3 2 2 0
KMT5A KMT5A Q9NQR1-2 Isoform 2 of N-lysine methyltransferase KMT5A chr12 Not Cancer Driver No 1 hippie 41 225 22 22 0
LASP1 LASP1 Q14847 LIM and SH3 domain protein 1 chr17 Census Yes 1 hippie 29 198 24 24 0
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 Census Yes 1 hippie 64 370 57 57 0
LENG1 LENG1 Q96BZ8 Leukocyte receptor cluster member 1 chr19 Not Cancer Driver No 1 hippie 39 264 39 39 0
LGALS14_ENST00000392052 LGALS14 Q8TCE9 Placental protein 13-like chr19 Not Cancer Driver No 1 hippie 35 0 0 0 0
LHX4 LHX4 Q969G2 LIM/homeobox protein Lhx4 chr1 Not Cancer Driver No 1 hippie 75 219 45 45 4
LMO1 LMO1 P25800 Rhombotin-1 chr11 Census Yes 1 hippie 23 0 0 0 0
LMO3_ENST00000534946 LMO3 Q8TAP4 LIM domain only protein 3 chr12 Not Cancer Driver No 1 hippie 30 1 0 0 0
LMO4 LMO4 P61968 LIM domain transcription factor LMO4 chr1 Not Cancer Driver No 1 hippie 30 11 1 1 0
LNPEP LNPEP Q9UIQ6 Leucyl-cystinyl aminopeptidase chr5 Not Cancer Driver No 1 hippie 115 103 8 8 0
LNX1 LNX1 Q8TBB1 E3 ubiquitin-protein ligase LNX chr4 Not Cancer Driver No 1 hippie 117 261 40 40 0
LYL1 LYL1 P12980 Protein lyl-1 chr19 Census Yes 1 hippie 15 243 11 11 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 Not Cancer Driver No 1 hippie 22 0 0 0 1
MAGOHB MAGOHB Q96A72 Protein mago nashi homolog 2 chr12 Not Cancer Driver No 1 hippie 15 6 1 1 0
MAPKBP1 MAPKBP1 O60336 Mitogen-activated protein kinase-binding protein 1 chr15 Not Cancer Driver No 1 hippie 166 786 67 67 0
MARF1 MARF1 Q9Y4F3 Meiosis regulator and mRNA stability factor 1 chr16 Not Cancer Driver No 1 hippie 199 524 73 73 0
MATN3 MATN3 O15232 Matrilin-3 chr2 Not Cancer Driver No 1 hippie 50 85 7 7 16
MEMO1_ENST00000404530 MEMO1 Q9Y316 Protein MEMO1 chr2 Not Cancer Driver No 1 hippie 38 5 0 0 0
MEN1 MEN1 O00255 Menin chr11 Census, Compendium Yes 1 hippie 73 228 15 15 90
MESP2 MESP2 Q0VG99 Mesoderm posterior protein 2 chr15 Not Cancer Driver No 3 hippie, biogrid 34 340 27 27 0
MLLT10_ENST00000377059 MLLT10 P55197 Protein AF-10 chr10 Census Yes 1 hippie 133 835 94 94 0
MORN4 MORN4 Q8NDC4 MORN repeat-containing protein 4 chr10 Not Cancer Driver No 1 hippie 18 15 0 0 0
MRFAP1L1 MRFAP1L1 Q96HT8 MORF4 family-associated protein 1-like 1 chr4 Not Cancer Driver No 1 hippie 12 59 5 5 0
MRPL10_ENST00000351111 MRPL10 Q7Z7H8 39S ribosomal protein L10, mitochondrial chr17 Not Cancer Driver No 1 hippie 37 40 6 6 0
MSC MSC O60682 Musculin chr8 Not Cancer Driver No 1 hippie 47 173 41 41 0
MSGN1 MSGN1 A6NI15 Mesogenin-1 chr2 Not Cancer Driver No 2 hippie, biogrid 54 161 44 44 0
MSRB3 MSRB3 Q8IXL7 Methionine-R-sulfoxide reductase B3 chr12 Not Cancer Driver No 1 hippie 49 42 14 14 1
MVP MVP Q14764 Major vault protein chr16 Not Cancer Driver No 1 hippie 141 285 31 31 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYF6 MYF6 P23409 Myogenic factor 6 chr12 Not Cancer Driver No 2 hippie, biogrid 89 118 44 44 0
MYO15B_ENST00000633867 MYO15B Q96JP2 Unconventional myosin-XVB chr17 Not Cancer Driver No 1 hippie 28 771 14 14 0
MYO5B MYO5B Q9ULV0 Unconventional myosin-Vb chr18 Not Cancer Driver No 1 hippie 269 505 68 68 14
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 Census Yes 1 hippie 45 246 33 33 0
MYOG MYOG P15173 Myogenin chr1 Not Cancer Driver No 3 hippie, biogrid 36 132 20 20 0
NANOG NANOG Q9H9S0 Homeobox protein NANOG chr12 Not Cancer Driver No 1 hippie 46 169 35 35 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 Not Cancer Driver No 1 hippie 89 88 19 19 0
NCKAP1_ENST00000361354 NCKAP1 Q9Y2A7 Nck-associated protein 1 chr2 Not Cancer Driver No 1 hippie 129 44 3 3 0
NDOR1_ENST00000344894 NDOR1 Q9UHB4 NADPH-dependent diflavin oxidoreductase 1 chr9 Not Cancer Driver No 1 hippie 60 67 7 7 0
NECTIN2 NECTIN2 Q92692 Nectin-2 chr19 Not Cancer Driver No 1 hippie 63 296 29 29 0
NEK6_ENST00000545174 NEK6 Q9HC98 Serine/threonine-protein kinase Nek6 chr9 Not Cancer Driver No 1 hippie 31 36 0 0 0
NEK8 NEK8 Q86SG6 Serine/threonine-protein kinase Nek8 chr17 Not Cancer Driver No 1 hippie 102 167 40 40 3
NES NES P48681 Nestin chr1 Not Cancer Driver No 1 hippie, biogrid 271 1474 253 253 0
NEU4_ENST00000407683 NEU4 Q8WWR8 Sialidase-4 chr2 Not Cancer Driver No 1 hippie 82 199 37 37 0
NEUROD1 NEUROD1 Q13562 Neurogenic differentiation factor 1 chr2 Not Cancer Driver No 4 hippie, biogrid 84 202 52 52 2
NEUROD4 NEUROD4 Q9HD90 Neurogenic differentiation factor 4 chr12 Not Cancer Driver No 1 hippie 123 236 83 83 0
NEUROG1 NEUROG1 Q92886 Neurogenin-1 chr5 Not Cancer Driver No 2 hippie, biogrid 27 178 18 18 0
NEUROG3 NEUROG3 Q9Y4Z2 Neurogenin-3 chr10 Not Cancer Driver No 2 hippie, biogrid 53 156 34 34 2
NFAM1 NFAM1 Q8NET5 NFAT activation molecule 1 chr22 Not Cancer Driver No 1 hippie 30 116 18 18 0
NFKBID NFKBID Q8NI38 NF-kappa-B inhibitor delta chr19 Not Cancer Driver No 1 hippie 47 124 20 20 0
NHLH1 NHLH1 Q02575 Helix-loop-helix protein 1 chr1 Not Cancer Driver No 1 hippie 30 90 22 22 0
NHLH2_ENST00000320238 NHLH2 Q02577 Helix-loop-helix protein 2 chr1 Not Cancer Driver No 2 hippie, biogrid 19 83 8 8 0
NME7 NME7 Q9Y5B8 Nucleoside diphosphate kinase 7 chr1 Not Cancer Driver No 1 hippie 53 0 0 0 0
NMUR2 NMUR2 Q9GZQ4 Neuromedin-U receptor 2 chr5 Not Cancer Driver No 1 hippie 139 5 1 1 0
NOL9 NOL9 Q5SY16 Polynucleotide 5'-hydroxyl-kinase NOL9 chr1 Not Cancer Driver No 1 hippie 73 102 8 8 0
NOXA1 NOXA1 Q86UR1 NADPH oxidase activator 1 chr9 Not Cancer Driver No 1 hippie 27 215 14 14 0
NR2C2AP_ENST00000331552 NR2C2AP Q86WQ0 Nuclear receptor 2C2-associated protein chr19 Not Cancer Driver No 1 hippie 19 4 0 0 0
NR4A1_ENST00000394825 NR4A1 P22736 Nuclear receptor subfamily 4 group A member 1 chr12 Not Cancer Driver No 1 hippie 62 252 24 24 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NUDT10_ENST00000356450 NUDT10 Q8NFP7 Diphosphoinositol polyphosphate phosphohydrolase 3-alpha chrX Not Cancer Driver No 1 hippie 29 68 8 8 0
NUDT22 NUDT22 Q9BRQ3 Uridine diphosphate glucose pyrophosphatase NUDT22 chr11 Not Cancer Driver No 1 hippie 23 73 6 6 0
NXPE2 NXPE2 Q96DL1 NXPE family member 2 chr11 Not Cancer Driver No 1 hippie 60 25 2 2 0
NXT2_ENST00000372106 NXT2 Q9NPJ8 NTF2-related export protein 2 chrX Not Cancer Driver No 1 hippie 12 0 0 0 0
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX Not Cancer Driver No 1 hippie 156 89 16 16 2
OLFM3 OLFM3 Q96PB7 Noelin-3 chr1 Not Cancer Driver No 1 hippie 148 44 17 17 0
ORC4_ENST00000392857 ORC4 O43929 Origin recognition complex subunit 4 chr2 Not Cancer Driver No 1 hippie 52 14 2 2 1
OSGIN1 OSGIN1 Q9UJX0 Oxidative stress-induced growth inhibitor 1 chr16 Not Cancer Driver No 1 hippie 57 79 10 10 0
OTUD4_ENST00000447906 OTUD4 Q01804 OTU domain-containing protein 4 chr4 Not Cancer Driver No 1 hippie 148 788 120 120 0
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 Not Cancer Driver No 1 hippie 119 320 34 34 0
PATE1 PATE1 Q8WXA2 Prostate and testis expressed protein 1 chr11 Not Cancer Driver No 1 hippie 36 0 0 0 0
PBLD PBLD P30039 Phenazine biosynthesis-like domain-containing protein chr10 Not Cancer Driver No 1 hippie 41 5 1 1 0
PIAS4 PIAS4 Q8N2W9 E3 SUMO-protein ligase PIAS4 chr19 Not Cancer Driver No 1 hippie 58 142 23 23 0
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 Not Cancer Driver No 1 hippie 17 115 12 12 0
PLEKHN1 PLEKHN1 Q494U1 Pleckstrin homology domain-containing family N member 1 chr1 Not Cancer Driver No 1 hippie 59 369 37 37 0
PML PML P29590 Protein PML chr15 Census, Compendium Yes 1 hippie 112 312 34 34 0
POLR1A POLR1A O95602 DNA-directed RNA polymerase I subunit RPA1 chr2 Not Cancer Driver No 1 hippie 208 361 64 64 2
POLR1C POLR1C O15160 DNA-directed RNA polymerases I and III subunit RPAC1 chr6 Not Cancer Driver No 1 hippie 34 28 3 3 13
POU5F1 POU5F1 Q01860 POU domain, class 5, transcription factor 1 chr6 Census Yes 1 hippie 36 186 12 12 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 Census Yes 1 hippie 72 44 4 4 3
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 Not Cancer Driver No 1 hippie 11 24 3 3 0
PPIL1 PPIL1 Q9Y3C6 Peptidyl-prolyl cis-trans isomerase-like 1 chr6 Not Cancer Driver No 1 hippie 25 42 11 11 3
PPP1R18_ENST00000615527 PPP1R18 Q6NYC8 Phostensin chr6 Not Cancer Driver No 1 hippie 51 585 49 49 0
PRDM6 PRDM6 Q9NQX0 Putative histone-lysine N-methyltransferase PRDM6 chr5 Not Cancer Driver No 1 hippie 29 241 7 7 2
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 Not Cancer Driver No 1 hippie 128 98 26 26 0
PRKAB2 PRKAB2 O43741 5'-AMP-activated protein kinase subunit beta-2 chr1 Not Cancer Driver No 1 hippie 31 110 12 12 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 Not Cancer Driver No 1 hippie 94 154 22 22 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 110 78 15 15 31
PSEN1 PSEN1 P49768 Presenilin-1 chr14 Not Cancer Driver No 1 hippie 61 134 21 21 96
PSMA1_ENST00000396394 PSMA1 P25786 Proteasome subunit alpha type-1 chr11 Not Cancer Driver No 1 hippie 48 51 9 9 0
PSMG2 PSMG2 Q969U7 Proteasome assembly chaperone 2 chr18 Not Cancer Driver No 1 hippie 19 3 0 0 0
PTF1A PTF1A Q7RTS3 Pancreas transcription factor 1 subunit alpha chr10 Not Cancer Driver No 1 hippie 35 231 31 31 0
PTGER3_ENST00000370931 PTGER3 P43115 Prostaglandin E2 receptor EP3 subtype chr1 Not Cancer Driver No 1 hippie 79 17 2 2 0
RAB41_ENST00000374473 RAB41 Q5JT25 Ras-related protein Rab-41 chrX Not Cancer Driver No 1 hippie 36 42 8 8 0
RABIF RABIF P47224 Guanine nucleotide exchange factor MSS4 chr1 Not Cancer Driver No 1 hippie 10 25 3 3 0
RAD51D_ENST00000394589 RAD51D O75771 DNA repair protein RAD51 homolog 4 chr17 Not Cancer Driver No 1 hippie 34 49 10 10 0
RCOR1 RCOR1 Q9UKL0 REST corepressor 1 chr14 Not Cancer Driver No 1 hippie, biogrid 47 324 28 28 0
RECK RECK O95980 Reversion-inducing cysteine-rich protein with Kazal motifs chr9 Not Cancer Driver No 1 hippie 115 9 2 2 0
RELA RELA Q04206 Transcription factor p65 chr11 Compendium Yes 1 hippie 75 400 48 48 0
RNF138 RNF138 Q8WVD3 E3 ubiquitin-protein ligase RNF138 chr18 Not Cancer Driver No 1 hippie 44 34 6 6 0
RNF14 RNF14 Q9UBS8 E3 ubiquitin-protein ligase RNF14 chr5 Not Cancer Driver No 1 hippie 52 40 8 8 0
RNF6 RNF6 Q9Y252 E3 ubiquitin-protein ligase RNF6 chr13 Compendium Yes 1 hippie 91 601 87 87 0
RSPH14 RSPH14 Q9UHP6 Radial spoke head 14 homolog chr22 Not Cancer Driver No 1 hippie 56 15 1 1 0
RTRAF RTRAF Q9Y224 RNA transcription, translation and transport factor protein chr14 Not Cancer Driver No 1 hippie 24 35 1 1 0
RUNX1T1_ENST00000614812 RUNX1T1 Q06455 Protein CBFA2T1 chr8 Census, Compendium Yes 3 hippie, biogrid 292 469 229 229 0
SCNM1 SCNM1 Q9BWG6 Sodium channel modifier 1 chr1 Not Cancer Driver No 1 hippie 31 172 23 23 0
SCOC SCOC Q9UIL1 Short coiled-coil protein chr4 Not Cancer Driver No 1 hippie 13 82 8 8 0
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 Not Cancer Driver No 1 hippie 39 17 2 2 0
SEC14L4 SEC14L4 Q9UDX3 SEC14-like protein 4 chr22 Not Cancer Driver No 1 hippie 68 60 14 14 0
SETDB1 SETDB1 Q15047 Histone-lysine N-methyltransferase SETDB1 chr1 Census, Compendium Yes 1 hippie 184 597 77 77 0
SGF29 SGF29 Q96ES7 SAGA-associated factor 29 chr16 Not Cancer Driver No 1 hippie 31 131 17 17 0
SIGLEC6 SIGLEC6 O43699 Sialic acid-binding Ig-like lectin 6 chr19 Not Cancer Driver No 1 hippie 124 130 40 40 0
SLC39A13 SLC39A13 Q96H72 Zinc transporter ZIP13 chr11 Not Cancer Driver No 1 hippie 39 18 2 2 0
SLC4A1AP SLC4A1AP Q9BWU0 Kanadaptin chr2 Not Cancer Driver No 1 hippie 88 613 60 60 0
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 Not Cancer Driver No 1 hippie 40 139 0 0 0
SMARCC2_ENST00000267064 SMARCC2 Q8TAQ2 SWI/SNF complex subunit SMARCC2 chr12 Not Cancer Driver No 1 hippie 175 876 133 133 4
SMARCE1 SMARCE1 Q969G3 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 chr17 Census Yes 1 hippie 47 332 36 36 2
SMCP SMCP P49901 Sperm mitochondrial-associated cysteine-rich protein chr1 Not Cancer Driver No 1 hippie 22 36 5 5 0
SMG9 SMG9 Q9H0W8 Nonsense-mediated mRNA decay factor SMG9 chr19 Not Cancer Driver No 1 hippie 43 256 23 23 0
SMOC1_ENST00000381280 SMOC1 Q9H4F8 SPARC-related modular calcium-binding protein 1 chr14 Not Cancer Driver No 1 hippie 81 195 47 47 3
SPATC1L SPATC1L Q9H0A9 Speriolin-like protein chr21 Not Cancer Driver No 1 hippie 30 179 11 11 0
SPG21_ENST00000433215 SPG21 Q9NZD8 Maspardin chr15 Not Cancer Driver No 1 hippie 31 13 1 1 0
SPO11 SPO11 Q9Y5K1 Meiotic recombination protein SPO11 chr20 Not Cancer Driver No 1 hippie 59 26 5 5 0
SRSF2 SRSF2 Q01130 Serine/arginine-rich splicing factor 2 chr17 Census, Compendium Yes 1 hippie 38 219 38 38 0
STAMBPL1_ENST00000371924 STAMBPL1 Q96FJ0 AMSH-like protease chr10 Not Cancer Driver No 1 hippie 48 70 7 7 0
STK16_ENST00000396738 STK16 O75716 Serine/threonine-protein kinase 16 chr2 Not Cancer Driver No 1 hippie 42 48 3 3 0
STX11 STX11 O75558 Syntaxin-11 chr6 Not Cancer Driver No 1 hippie 71 48 7 7 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
SZT2_ENST00000634258 SZT2 Q5T011 KICSTOR complex protein SZT2 chr1 Not Cancer Driver No 1 hippie 381 1292 161 161 1
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 Census Yes 2 hippie, biogrid 54 305 53 53 0
TAL2 TAL2 Q16559 T-cell acute lymphocytic leukemia protein 2 chr9 Census Yes 2 hippie, biogrid 18 81 14 14 0
TAPBPL TAPBPL Q9BX59 Tapasin-related protein chr12 Not Cancer Driver No 1 hippie 53 67 8 8 0
TCEA2 TCEA2 Q15560 Transcription elongation factor A protein 2 chr20 Not Cancer Driver No 1 hippie 45 194 40 40 0
TCF12_ENST00000267811 TCF12 Q99081 Transcription factor 12 chr15 Census Yes 3 hippie, biogrid 105 680 105 105 3
TCF15 TCF15 Q12870 Transcription factor 15 chr20 Not Cancer Driver No 1 hippie, biogrid 19 134 4 4 0
TCF21 TCF21 O43680 Transcription factor 21 chr6 Not Cancer Driver No 1 hippie 55 120 40 40 0
TCF23 TCF23 Q7RTU1 Transcription factor 23 chr2 Not Cancer Driver No 2 hippie, biogrid 45 156 33 33 0
TCF3 TCF3 P15923 Transcription factor E2-alpha chr19 Census Yes 3 hippie, biogrid 52 649 52 52 0
TCF4_ENST00000564999 TCF4 P15884 Transcription factor 4 chr18 Compendium Yes 1 hippie 141 662 136 136 13
TCL1A TCL1A P56279 T-cell leukemia/lymphoma protein 1A chr14 Census Yes 1 hippie 30 5 1 1 0
TDG TDG Q13569 G/T mismatch-specific thymine DNA glycosylase chr12 Not Cancer Driver No 1 hippie 75 185 31 31 0
TLE1 TLE1 Q04724 Transducin-like enhancer protein 1 chr9 Not Cancer Driver No 1 hippie 111 381 53 53 0
TLE3 TLE3 Q04726 Transducin-like enhancer protein 3 chr15 Not Cancer Driver No 1 hippie 87 381 50 50 0
TMEM213 TMEM213 A2RRL7 Transmembrane protein 213 chr7 Not Cancer Driver No 1 hippie 15 14 4 4 0
TOP2A TOP2A P11388 DNA topoisomerase 2-alpha chr17 Compendium Yes 1 hippie 150 508 59 59 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 Census, Compendium Yes 1 hippie 229 398 143 143 28
TRAPPC2L_ENST00000301021 TRAPPC2L Q9UL33 Trafficking protein particle complex subunit 2-like protein chr16 Not Cancer Driver No 1 hippie 21 0 0 0 1
TRIB2 TRIB2 Q92519 Tribbles homolog 2 chr2 Not Cancer Driver No 1 hippie 64 43 5 5 0
TRIM24 TRIM24 O15164 Transcription intermediary factor 1-alpha chr7 Census, Compendium Yes 1 hippie 120 537 61 61 0
TRIM33 TRIM33 Q9UPN9 E3 ubiquitin-protein ligase TRIM33 chr1 Census, Compendium Yes 1 hippie 110 617 51 51 0
TRIM68 TRIM68 Q6AZZ1 E3 ubiquitin-protein ligase TRIM68 chr11 Not Cancer Driver No 1 hippie 74 37 7 7 0
TRIML2 TRIML2 Q8N7C3 Probable E3 ubiquitin-protein ligase TRIML2 chr4 Not Cancer Driver No 1 hippie 165 77 28 28 0
TSPOAP1 TSPOAP1 O95153 Peripheral-type benzodiazepine receptor-associated protein 1 chr17 Not Cancer Driver No 1 hippie 268 1522 213 213 0
TSSC4 TSSC4 Q9Y5U2 Protein TSSC4 chr11 Not Cancer Driver No 1 hippie 35 326 35 35 0
TSSK3 TSSK3 Q96PN8 Testis-specific serine/threonine-protein kinase 3 chr1 Not Cancer Driver No 1 hippie 30 0 0 0 0
TSTD2 TSTD2 Q5T7W7 Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 chr9 Not Cancer Driver No 1 hippie 50 44 0 0 0
TTF2 TTF2 Q9UNY4 Transcription termination factor 2 chr1 Not Cancer Driver No 1 hippie 118 550 50 50 0
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 Not Cancer Driver No 3 hippie, biogrid 23 132 11 11 7
TWIST2 TWIST2 Q8WVJ9 Twist-related protein 2 chr2 Not Cancer Driver No 3 hippie, biogrid 11 90 2 2 4
TXNL4B TXNL4B Q9NX01 Thioredoxin-like protein 4B chr16 Not Cancer Driver No 1 hippie 17 0 0 0 0
UBASH3B UBASH3B Q8TF42 Ubiquitin-associated and SH3 domain-containing protein B chr11 Not Cancer Driver No 1 hippie 86 73 6 6 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 Not Cancer Driver No 1 hippie 16 16 3 3 0
UHRF2 UHRF2 Q96PU4 E3 ubiquitin-protein ligase UHRF2 chr9 Not Cancer Driver No 1 hippie 88 253 22 22 0
USP11 USP11 P51784 Ubiquitin carboxyl-terminal hydrolase 11 chrX Not Cancer Driver No 1 hippie 140 210 28 28 0
USP4 USP4 Q13107 Ubiquitin carboxyl-terminal hydrolase 4 chr3 Not Cancer Driver No 1 hippie 102 286 22 22 0
UTP23 UTP23 Q9BRU9 rRNA-processing protein UTP23 homolog chr8 Not Cancer Driver No 1 hippie 35 97 16 16 0
VPS28_ENST00000292510 VPS28 Q9UK41 Vacuolar protein sorting-associated protein 28 homolog chr8 Not Cancer Driver No 1 hippie 28 31 5 5 0
WASF1_ENST00000392586 WASF1 Q92558 Wiskott-Aldrich syndrome protein family member 1 chr6 Not Cancer Driver No 1 hippie 63 445 49 49 0
WASF2 WASF2 Q9Y6W5 Wiskott-Aldrich syndrome protein family member 2 chr1 Not Cancer Driver No 1 hippie 61 400 43 43 0
WDR47_ENST00000369962 WDR47 O94967 WD repeat-containing protein 47 chr1 Not Cancer Driver No 1 hippie 113 317 35 35 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 1 hippie 26 77 9 9 2
ZDHHC24 ZDHHC24 Q6UX98 Probable palmitoyltransferase ZDHHC24 chr11 Not Cancer Driver No 1 hippie 23 8 0 0 0
ZMYND10 ZMYND10 O75800 Zinc finger MYND domain-containing protein 10 chr3 Not Cancer Driver No 1 hippie 40 38 6 6 5
ZNF124 ZNF124 Q15973 Zinc finger protein 124 chr1 Not Cancer Driver No 1 hippie 44 83 12 12 0
ZNF417 ZNF417 Q8TAU3 Zinc finger protein 417 chr19 Not Cancer Driver No 1 hippie 76 156 23 23 0
ZNF587 ZNF587 Q96SQ5 Zinc finger protein 587 chr19 Not Cancer Driver No 1 hippie 81 155 22 22 0
ZNF688 ZNF688 P0C7X2 Zinc finger protein 688 chr16 Not Cancer Driver No 1 hippie 32 223 28 28 0