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TAL1 ,TAL1 ,P17542
  • Uniprot Accession= P17542
  • Ensembl Transcript= ENST00000294339.3
  • Uniprot Name= TAL1
  • Name= T-cell acute lymphocytic leukemia protein 1
  • Chromosome= chr1
  • Driver status= Census
  • Number of Interaction partner in intact: 42
  • Number of Interaction partner in biogrid: 8
  • Number of Interaction partner in hippie: 88
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ATP5F1C ATP5F1C P36542 ATP synthase subunit gamma, mitochondrial chr10 Not Cancer Driver No 1 intact, hippie 39 11 0 0 0
BCL11B BCL11B Q9C0K0 B-cell lymphoma/leukemia 11B chr14 Census, Compendium Yes 1 intact, hippie 156 699 114 114 2
BRD1_ENST00000216267 BRD1 O95696 Bromodomain-containing protein 1 chr22 Not Cancer Driver No 1 hippie 171 425 68 68 0
CBFA2T2 CBFA2T2 O43439 Protein CBFA2T2 chr20 Not Cancer Driver No 1 hippie 89 457 58 58 0
CBFA2T3 CBFA2T3 O75081 Protein CBFA2T3 chr16 Census, Compendium Yes 1 hippie 83 502 70 70 0
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 Not Cancer Driver No 1 intact, hippie 50 34 2 2 0
CHD3_ENST00000330494 CHD3 Q12873 Chromodomain-helicase-DNA-binding protein 3 chr17 Not Cancer Driver No 1 hippie 235 1015 122 122 18
CHD4 CHD4 Q14839 Chromodomain-helicase-DNA-binding protein 4 chr12 Census, Compendium Yes 1 intact, hippie 419 974 177 177 6
CREBBP CREBBP Q92793 CREB-binding protein chr16 Census, Compendium Yes 1 intact, hippie 412 1796 247 247 33
CRK CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 1 hippie 30 197 23 23 0
CTCF CTCF P49711 Transcriptional repressor CTCF chr16 Census, Compendium Yes 1 hippie 151 481 83 83 1
DARS DARS1 P14868 Aspartate--tRNA ligase, cytoplasmic chr2 Not Cancer Driver No 1 intact 55 110 21 21 8
DBT DBT P11182 Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie 64 81 11 11 3
DLAT DLAT P10515 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial chr11 Not Cancer Driver No 1 intact, hippie 63 294 42 42 0
DRG1 DRG1 Q9Y295 Developmentally-regulated GTP-binding protein 1 chr22 Not Cancer Driver No 1 hippie 35 31 0 0 0
DYNC1H1 DYNC1H1 Q14204 Cytoplasmic dynein 1 heavy chain 1 chr14 Not Cancer Driver No 1 intact, hippie 505 495 62 62 21
EEF1D_ENST00000395119 EEF1D P29692 Elongation factor 1-delta chr8 Not Cancer Driver No 1 intact, hippie 40 153 22 22 0
ELSPBP1 ELSPBP1 Q96BH3 Epididymal sperm-binding protein 1 chr19 Not Cancer Driver No 1 hippie 54 0 0 0 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
ETS1_ENST00000319397 ETS1 P14921 Protein C-ets-1 chr11 Not Cancer Driver No 1 hippie 68 78 9 9 0
GATA1 GATA1 P15976 Erythroid transcription factor chrX Census, Compendium Yes 1 hippie 68 242 41 41 5
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 Census, Compendium Yes 1 hippie 72 370 49 49 6
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 Census, Compendium Yes 2 intact, hippie 111 364 87 87 2
HADHB HADHB P55084 Trifunctional enzyme subunit beta, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 71 41 9 9 14
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 2 intact, hippie 47 135 10 10 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 2 intact, hippie 46 145 14 14 0
HEXIM2_ENST00000592695 HEXIM2 Q96MH2 Protein HEXIM2 chr17 Not Cancer Driver No 1 intact, hippie 35 286 35 35 0
HIVEP1 HIVEP1 P15822 Zinc finger protein 40 chr6 Not Cancer Driver No 1 hippie 344 2238 292 292 0
HOXB9 HOXB9 P17482 Homeobox protein Hox-B9 chr17 Not Cancer Driver No 1 hippie 28 191 27 27 0
IARS IARS1 P41252 Isoleucine--tRNA ligase, cytoplasmic chr9 Not Cancer Driver No 1 intact 130 28 4 4 4
ID4 ID4 P47928 DNA-binding protein inhibitor ID-4 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 4 71 1 1 0
IRF2BP2 IRF2BP2 Q7Z5L9 Interferon regulatory factor 2-binding protein 2 chr1 Not Cancer Driver No 1 hippie 42 451 26 26 1
KAT2B KAT2B Q92831 Histone acetyltransferase KAT2B chr3 Not Cancer Driver No 1 hippie 107 266 27 27 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 Not Cancer Driver No 1 intact, hippie 67 291 28 28 3
LARS LARS1 Q9P2J5 Leucine--tRNA ligase, cytoplasmic chr5 Not Cancer Driver No 1 intact 133 97 10 10 1
LDB1 LDB1 Q86U70 LIM domain-binding protein 1 chr10 Compendium Yes 2 hippie, biogrid 56 177 29 29 0
LGALS3BP LGALS3BP Q08380 Galectin-3-binding protein chr17 Not Cancer Driver No 1 intact, hippie 62 9 0 0 0
LMO1 LMO1 P25800 Rhombotin-1 chr11 Census Yes 1 hippie 23 0 0 0 0
LMO2_ENST00000395833 LMO2 P25791 Rhombotin-2 chr11 Census Yes 2 intact, hippie 35 14 1 1 0
LYL1 LYL1 P12980 Protein lyl-1 chr19 Census Yes 1 intact, hippie 15 243 11 11 0
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie 38 49 5 5 0
MARS MARS1 P56192 Methionine--tRNA ligase, cytoplasmic chr12 Not Cancer Driver No 1 intact 91 151 16 16 8
MYBBP1A_ENST00000254718 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 Not Cancer Driver No 1 intact, hippie 144 463 47 47 0
MYB_ENST00000367814 MYB P10242 Transcriptional activator Myb chr6 Census Yes 1 intact, hippie 82 528 69 69 0
NCAPG2_ENST00000356309 NCAPG2 Q86XI2 Condensin-2 complex subunit G2 chr7 Not Cancer Driver No 1 hippie 113 72 8 8 3
NPNT_ENST00000379987 NPNT Q6UXI9 Nephronectin chr4 Not Cancer Driver No 1 hippie, biogrid 90 218 33 33 0
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 Not Cancer Driver No 1 hippie 119 320 34 34 0
PPM1G PPM1G O15355 Protein phosphatase 1G chr2 Not Cancer Driver No 1 hippie 51 359 39 39 0
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 Not Cancer Driver No 1 hippie 147 28 9 9 0
PRPF40A PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 hippie 83 694 57 57 0
PSMA6 PSMA6 P60900 Proteasome subunit alpha type-6 chr14 Not Cancer Driver No 1 intact, hippie 37 2 1 1 0
PSMD1 PSMD1 Q99460 26S proteasome non-ATPase regulatory subunit 1 chr2 Not Cancer Driver No 1 intact, hippie 110 201 19 19 0
PSMD8 PSMD8 P48556 26S proteasome non-ATPase regulatory subunit 8 chr19 Not Cancer Driver No 1 intact, hippie 20 78 2 2 0
PTMA PTMA P06454 Prothymosin alpha chr2 Compendium Yes 1 hippie 10 111 10 10 0
PTMS_ENST00000309083 PTMS P20962 Parathymosin chr12 Not Cancer Driver No 1 intact, hippie 10 102 10 10 0
QARS QARS1 P47897 Glutamine--tRNA ligase chr3 Not Cancer Driver No 1 intact 101 106 16 16 4
RARS RARS1 P54136 Arginine--tRNA ligase, cytoplasmic chr5 Not Cancer Driver No 1 intact 72 41 3 3 2
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 Census, Compendium Yes 1 hippie 140 282 32 32 22
RBBP7_ENST00000380087 RBBP7 Q16576 Histone-binding protein RBBP7 chrX Not Cancer Driver No 1 intact, hippie 67 138 19 19 0
RBM25 RBM25 P49756 RNA-binding protein 25 chr14 Not Cancer Driver No 1 intact, hippie 124 549 88 88 0
RCC1_ENST00000373833 RCC1 P18754 Regulator of chromosome condensation chr1 Not Cancer Driver No 1 hippie 54 143 15 15 0
RCOR1 RCOR1 Q9UKL0 REST corepressor 1 chr14 Not Cancer Driver No 1 intact, hippie 47 324 28 28 0
RPL13A RPL13A P40429 60S ribosomal protein L13a chr19 Not Cancer Driver No 1 hippie 27 33 2 2 0
RPL34_ENST00000502534 RPL34 P49207 60S ribosomal protein L34 chr4 Not Cancer Driver No 1 intact, hippie 11 31 1 1 0
RPS13 RPS13 P62277 40S ribosomal protein S13 chr11 Not Cancer Driver No 1 intact, hippie 19 18 5 5 0
RSL1D1 RSL1D1 O76021 Ribosomal L1 domain-containing protein 1 chr16 Not Cancer Driver No 1 intact, hippie 61 275 33 33 0
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 Census, Compendium Yes 2 intact, hippie 81 360 58 58 2
SATB1_ENST00000454909 SATB1 Q01826 DNA-binding protein SATB1 chr3 Compendium Yes 1 hippie 130 482 84 84 12
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 Compendium Yes 1 hippie 172 617 73 73 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 Not Cancer Driver No 1 hippie, biogrid 70 435 31 31 0
SIRT5 SIRT5 Q9NXA8 NAD-dependent protein deacylase sirtuin-5, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 41 55 7 7 0
SKP2 SKP2 Q13309 S-phase kinase-associated protein 2 chr5 Not Cancer Driver No 1 hippie 52 52 6 6 0
SP1 SP1 P08047 Transcription factor Sp1 chr12 Not Cancer Driver No 1 hippie 96 599 71 71 0
SPTBN1 SPTBN1 Q01082 Spectrin beta chain, non-erythrocytic 1 chr2 Not Cancer Driver No 1 intact, hippie 311 869 123 123 0
SSBP1_ENST00000484178 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 Not Cancer Driver No 1 hippie 27 0 0 0 6
SSBP2_ENST00000320672 SSBP2 P81877 Single-stranded DNA-binding protein 2 chr5 Not Cancer Driver No 1 hippie 36 296 29 29 0
SSBP3 SSBP3 Q9BWW4 Single-stranded DNA-binding protein 3 chr1 Not Cancer Driver No 3 intact, hippie 51 321 42 42 0
STIP1_ENST00000305218 STIP1 P31948 Stress-induced-phosphoprotein 1 chr11 Not Cancer Driver No 1 hippie 74 270 39 39 0
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 Not Cancer Driver No 1 hippie 35 112 14 14 12
SUPT16H SUPT16H Q9Y5B9 FACT complex subunit SPT16 chr14 Not Cancer Driver No 1 hippie 147 301 44 44 0
SUV39H1_ENST00000376687 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX Not Cancer Driver No 1 hippie 59 15 1 1 0
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 Census Yes 1 hippie 54 305 53 53 0
TAL2 TAL2 Q16559 T-cell acute lymphocytic leukemia protein 2 chr9 Census Yes 1 intact, hippie 18 81 14 14 0
TCF12_ENST00000267811 TCF12 Q99081 Transcription factor 12 chr15 Census Yes 2 hippie, biogrid 105 680 105 105 3
TCF3 TCF3 P15923 Transcription factor E2-alpha chr19 Census Yes 2 hippie, biogrid 52 649 52 52 0
TCF4_ENST00000564999 TCF4 P15884 Transcription factor 4 chr18 Compendium Yes 2 hippie, biogrid 141 662 136 136 13
TNPO2 TNPO2 O14787 Transportin-2 chr19 Not Cancer Driver No 1 hippie 99 76 10 10 0
TOP1 TOP1 P11387 DNA topoisomerase 1 chr20 Census, Compendium Yes 1 hippie 93 391 53 53 0
TRIM27 TRIM27 P14373 Zinc finger protein RFP chr6 Census Yes 1 hippie 59 87 11 11 0
TRIM33 TRIM33 Q9UPN9 E3 ubiquitin-protein ligase TRIM33 chr1 Census, Compendium Yes 1 hippie 110 617 51 51 0
TRRAP TRRAP Q9Y4A5 Transformation/transcription domain-associated protein chr7 Census, Compendium Yes 1 hippie 554 402 59 59 8
UBR4 UBR4 Q5T4S7 E3 ubiquitin-protein ligase UBR4 chr1 Not Cancer Driver No 1 intact, hippie 565 1066 119 119 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 Not Cancer Driver No 1 hippie 66 140 12 12 0
ZHX1_ENST00000522655 ZHX1 Q9UKY1 Zinc fingers and homeoboxes protein 1 chr8 Not Cancer Driver No 1 hippie 109 575 68 68 0