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SYT6_ENST00000610222 ,SYT6 ,Q5T7P8
  • Uniprot Accession= Q5T7P8
  • Ensembl Transcript= ENST00000610222.1
  • Uniprot Name= SYT6
  • Name= Synaptotagmin-6
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 25
  • Number of Interaction partner in biogrid: 82
  • Number of Interaction partner in hippie: 120
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AEN AEN Q8WTP8 Apoptosis-enhancing nuclease chr15 Not Cancer Driver No 1 intact, hippie 39 183 21 21 0
AHCYL1 AHCYL1 O43865 S-adenosylhomocysteine hydrolase-like protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 58 108 10 10 0
AHCYL2 AHCYL2 Q96HN2 Adenosylhomocysteinase 3 chr7 Not Cancer Driver No 3 intact, hippie, biogrid 76 208 23 23 0
AK4 AK4 P27144 Adenylate kinase 4, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 26 24 3 3 0
ALCAM ALCAM Q13740 CD166 antigen chr3 Not Cancer Driver No 1 hippie, biogrid 89 96 19 19 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ARL8A ARL8A Q96BM9 ADP-ribosylation factor-like protein 8A chr1 Not Cancer Driver No 1 hippie, biogrid 23 0 0 0 0
ATP6V0A2 ATP6V0A2 Q9Y487 V-type proton ATPase 116 kDa subunit a 2 chr12 Not Cancer Driver No 1 hippie, biogrid 88 36 6 6 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX Not Cancer Driver No 1 hippie, biogrid 37 104 14 14 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
CCDC136 CCDC136 Q96JN2 Coiled-coil domain-containing protein 136 chr7 Not Cancer Driver No 1 hippie 150 818 114 114 0
CCDC57_ENST00000392347 CCDC57 Q2TAC2 Coiled-coil domain-containing protein 57 chr17 Not Cancer Driver No 1 intact, hippie 107 595 65 65 0
CETN3_ENST00000283122 CETN3 O15182 Centrin-3 chr5 Not Cancer Driver No 1 hippie, biogrid 13 19 1 1 0
CKAP5 CKAP5 Q14008 Cytoskeleton-associated protein 5 chr11 Not Cancer Driver No 1 hippie, biogrid 198 634 64 64 0
CLPP CLPP Q16740 ATP-dependent Clp protease proteolytic subunit, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 22 83 9 9 3
CNTROB_ENST00000563694 CNTROB Q8N137 Centrobin chr17 Not Cancer Driver No 1 intact, hippie 97 837 93 93 0
CSE1L CSE1L P55060 Exportin-2 chr20 Not Cancer Driver No 1 hippie, biogrid 109 32 5 5 0
CSTF3 CSTF3 Q12996 Cleavage stimulation factor subunit 3 chr11 Not Cancer Driver No 1 hippie, biogrid 82 122 15 15 0
CTBP2_ENST00000494626 CTBP2 P56545 C-terminal-binding protein 2 chr10 Not Cancer Driver No 1 hippie, biogrid 48 94 4 4 0
CYB5R3_ENST00000352397 CYB5R3 P00387 NADH-cytochrome b5 reductase 3 chr22 Not Cancer Driver No 1 hippie, biogrid 42 24 3 3 9
DIS3 DIS3 Q9Y2L1 Exosome complex exonuclease RRP44 chr13 Compendium Yes 1 hippie, biogrid 121 235 32 32 0
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 Census Yes 1 hippie, biogrid 138 270 43 43 22
DVL3 DVL3 Q92997 Segment polarity protein dishevelled homolog DVL-3 chr3 Not Cancer Driver No 2 intact, hippie 97 437 58 58 0
EDC4 EDC4 Q6P2E9 Enhancer of mRNA-decapping protein 4 chr16 Not Cancer Driver No 1 hippie, biogrid 144 702 69 69 0
EHD4 EHD4 Q9H223 EH domain-containing protein 4 chr15 Not Cancer Driver No 1 hippie, biogrid 54 98 7 7 0
F11R F11R Q9Y624 Junctional adhesion molecule A chr1 Not Cancer Driver No 1 hippie, biogrid 47 72 15 15 0
FAM162A FAM162A Q96A26 Protein FAM162A chr3 Not Cancer Driver No 1 hippie, biogrid 18 53 8 8 0
FXR1 FXR1 P51114 Fragile X mental retardation syndrome-related protein 1 chr3 Not Cancer Driver No 1 intact, hippie 88 312 53 53 0
FXR2 FXR2 P51116 Fragile X mental retardation syndrome-related protein 2 chr17 Not Cancer Driver No 2 intact, hippie 68 388 42 42 0
GALE GALE Q14376 UDP-glucose 4-epimerase chr1 Not Cancer Driver No 1 hippie, biogrid 32 24 2 2 16
GAPDH GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 Not Cancer Driver No 1 hippie, biogrid 39 24 3 3 0
GLRX3 GLRX3 O76003 Glutaredoxin-3 chr10 Not Cancer Driver No 1 hippie, biogrid 52 24 4 4 0
GMCL1 GMCL1 Q96IK5 Germ cell-less protein-like 1 chr2 Not Cancer Driver No 1 intact, hippie 33 80 2 2 0
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 Not Cancer Driver No 2 intact, hippie 115 854 96 96 0
GSTK1_ENST00000358406 GSTK1 Q9Y2Q3 Glutathione S-transferase kappa 1 chr7 Not Cancer Driver No 1 hippie, biogrid 33 30 3 3 0
HDGFL2 HDGFL2 Q7Z4V5 Hepatoma-derived growth factor-related protein 2 chr19 Not Cancer Driver No 1 hippie 59 622 57 57 0
HDLBP_ENST00000391976 HDLBP Q00341 Vigilin chr2 Not Cancer Driver No 1 hippie, biogrid 195 555 87 87 0
HMBOX1_ENST00000397358 HMBOX1 Q6NT76 Homeobox-containing protein 1 chr8 Not Cancer Driver No 1 intact, hippie 55 319 41 41 0
HMOX2_ENST00000406590 HMOX2 P30519 Heme oxygenase 2 chr16 Not Cancer Driver No 1 hippie, biogrid 27 74 10 10 0
HOOK2 HOOK2 Q96ED9 Protein Hook homolog 2 chr19 Not Cancer Driver No 1 intact, hippie 94 487 62 62 0
HTT HTT P42858 Huntingtin chr4 Not Cancer Driver No 1 intact, hippie 336 666 69 69 2
IDH2 IDH2 P48735 Isocitrate dehydrogenase [NADP], mitochondrial chr15 Census, Compendium Yes 1 hippie, biogrid 74 59 1 1 7
KANK2_ENST00000586659 KANK2 Q63ZY3 KN motif and ankyrin repeat domain-containing protein 2 chr19 Not Cancer Driver No 1 hippie 107 531 71 71 3
KCTD9 KCTD9 Q7L273 BTB/POZ domain-containing protein KCTD9 chr8 Not Cancer Driver No 2 intact, hippie 48 27 3 3 0
KIF24 KIF24 Q5T7B8 Kinesin-like protein KIF24 chr9 Not Cancer Driver No 1 intact, hippie 126 898 90 90 0
KIFC3_ENST00000379655 KIFC3 Q9BVG8 Kinesin-like protein KIFC3 chr16 Not Cancer Driver No 1 intact, hippie 84 487 42 42 0
KRT40_ENST00000398486 KRT40 Q6A162 Keratin, type I cytoskeletal 40 chr17 Not Cancer Driver No 1 intact, hippie 70 6 1 1 0
LARS2_ENST00000645846 LARS2 Q15031 Leucine--tRNA ligase, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 74 80 8 8 3
LETM1 LETM1 O95202 Mitochondrial proton/calcium exchanger protein chr4 Not Cancer Driver No 1 hippie, biogrid 77 286 28 28 0
LIG1 LIG1 P18858 DNA ligase 1 chr19 Not Cancer Driver No 1 hippie, biogrid 137 397 62 62 0
LMNA LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie 68 544 49 49 131
LZTS1 LZTS1 Q9Y250 Leucine zipper putative tumor suppressor 1 chr8 Not Cancer Driver No 1 intact, hippie 102 467 75 75 0
MAD1L1_ENST00000399654 MAD1L1 Q9Y6D9 Mitotic spindle assembly checkpoint protein MAD1 chr7 Not Cancer Driver No 1 hippie 117 526 77 77 0
MADD MADD Q8WXG6 MAP kinase-activating death domain protein chr11 Not Cancer Driver No 3 intact, hippie, biogrid 207 723 81 81 4
MAP4K4_ENST00000347699 MAP4K4 O95819 Mitogen-activated protein kinase kinase kinase kinase 4 chr2 Not Cancer Driver No 1 hippie, biogrid 143 649 55 55 0
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie, biogrid 38 49 5 5 0
MCC_ENST00000302475 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 1 intact, hippie 136 589 92 92 0
MCTS1_ENST00000371317 MCTS1 Q9ULC4 Malignant T-cell-amplified sequence 1 chrX Not Cancer Driver No 1 hippie, biogrid 34 0 0 0 0
MIPEP MIPEP Q99797 Mitochondrial intermediate peptidase chr13 Not Cancer Driver No 1 hippie, biogrid 77 40 2 2 3
MTUS2 MTUS2 Q5JR59 Microtubule-associated tumor suppressor candidate 2 chr13 Not Cancer Driver No 1 hippie 370 1208 329 329 0
NAA15 NAA15 Q9BXJ9 N-alpha-acetyltransferase 15, NatA auxiliary subunit chr4 Not Cancer Driver No 1 hippie, biogrid 95 115 17 17 0
NAA50 NAA50 Q9GZZ1 N-alpha-acetyltransferase 50 chr3 Not Cancer Driver No 1 hippie, biogrid 14 14 1 1 0
NCAPD2 NCAPD2 Q15021 Condensin complex subunit 1 chr12 Not Cancer Driver No 1 hippie, biogrid 124 345 35 35 0
NRXN1_ENST00000406316 NRXN1 Q9ULB1 Neurexin-1 chr2 Not Cancer Driver No 1 hippie 593 301 110 110 0
NSDHL NSDHL Q15738 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating chrX Not Cancer Driver No 1 hippie, biogrid 60 39 6 6 3
PBK_ENST00000301905 PBK Q96KB5 Lymphokine-activated killer T-cell-originated protein kinase chr8 Not Cancer Driver No 1 hippie, biogrid 23 92 6 6 0
PDS5A PDS5A Q29RF7 Sister chromatid cohesion protein PDS5 homolog A chr4 Not Cancer Driver No 1 hippie, biogrid 150 295 34 34 0
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 Census, Compendium Yes 1 hippie 205 148 40 40 0
PRPF40A PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 hippie, biogrid 83 694 57 57 0
PRPS1 PRPS1 P60891 Ribose-phosphate pyrophosphokinase 1 chrX Not Cancer Driver No 1 hippie, biogrid 50 0 0 0 14
PTGES2 PTGES2 Q9H7Z7 Prostaglandin E synthase 2 chr9 Not Cancer Driver No 1 hippie, biogrid 30 30 1 1 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 1 hippie, biogrid 49 140 25 25 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 Census, Compendium Yes 1 hippie, biogrid 129 260 38 38 60
PTRH2_ENST00000470557 PTRH2 Q9Y3E5 Peptidyl-tRNA hydrolase 2, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 14 19 2 2 1
PUS7_ENST00000469408 PUS7 Q96PZ0 Pseudouridylate synthase 7 homolog chr7 Not Cancer Driver No 1 hippie, biogrid 73 162 17 17 1
RAB14 RAB14 P61106 Ras-related protein Rab-14 chr9 Not Cancer Driver No 1 hippie, biogrid 20 41 4 4 0
RAB1B RAB1B Q9H0U4 Ras-related protein Rab-1B chr11 Not Cancer Driver No 1 hippie, biogrid 24 40 3 3 0
RAB21 RAB21 Q9UL25 Ras-related protein Rab-21 chr12 Not Cancer Driver No 1 hippie, biogrid 23 59 4 4 0
RAP1B_ENST00000393436 RAP1B P61224 Ras-related protein Rap-1b chr12 Not Cancer Driver No 1 hippie, biogrid 26 14 3 3 0
RAVER1_ENST00000615032 RAVER1 Q8IY67 Ribonucleoprotein PTB-binding 1 chr19 Not Cancer Driver No 1 hippie, biogrid 61 330 22 22 0
RDH11 RDH11 Q8TC12 Retinol dehydrogenase 11 chr14 Not Cancer Driver No 1 hippie, biogrid 25 2 0 0 0
RMDN1 RMDN1 Q96DB5 Regulator of microtubule dynamics protein 1 chr8 Not Cancer Driver No 1 hippie, biogrid 25 17 0 0 0
RNF40 RNF40 O75150 E3 ubiquitin-protein ligase BRE1B chr16 Not Cancer Driver No 1 hippie, biogrid 132 645 80 80 0
RPRD1B RPRD1B Q9NQG5 Regulation of nuclear pre-mRNA domain-containing protein 1B chr20 Not Cancer Driver No 1 hippie, biogrid 34 155 16 16 0
SAR1B SAR1B Q9Y6B6 GTP-binding protein SAR1b chr5 Not Cancer Driver No 1 hippie, biogrid 17 4 0 0 5
SCARB2 SCARB2 Q14108 Lysosome membrane protein 2 chr4 Not Cancer Driver No 1 hippie, biogrid 61 13 3 3 1
SFXN1 SFXN1 Q9H9B4 Sideroflexin-1 chr5 Not Cancer Driver No 1 hippie, biogrid 31 29 1 1 0
SLC29A1_ENST00000371708 SLC29A1 Q99808 Equilibrative nucleoside transporter 1 chr6 Not Cancer Driver No 1 hippie, biogrid 51 27 4 4 0
SND1 SND1 Q7KZF4 Staphylococcal nuclease domain-containing protein 1 chr7 Census Yes 1 hippie, biogrid 127 258 48 48 0
SRPRA SRPRA P08240 Signal recognition particle receptor subunit alpha chr11 Not Cancer Driver No 1 hippie 95 232 40 40 0
STK25 STK25 O00506 Serine/threonine-protein kinase 25 chr2 Not Cancer Driver No 1 hippie, biogrid 42 170 15 15 0
STXBP2_ENST00000221283 STXBP2 Q15833 Syntaxin-binding protein 2 chr19 Not Cancer Driver No 1 hippie, biogrid 77 80 13 13 5
SUPT5H SUPT5H O00267 Transcription elongation factor SPT5 chr19 Not Cancer Driver No 1 hippie, biogrid 165 572 87 87 0
SYT10 SYT10 Q6XYQ8 Synaptotagmin-10 chr12 Not Cancer Driver No 3 hippie, biogrid 155 163 56 56 0
SYT3_ENST00000593901 SYT3 Q9BQG1 Synaptotagmin-3 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 119 268 44 44 0
SYT6_ENST00000610222 SYT6 Q5T7P8 Synaptotagmin-6 chr1 Not Cancer Driver No 1 hippie 98 137 18 18 0
TBRG4_ENST00000494076 TBRG4 Q969Z0 FAST kinase domain-containing protein 4 chr7 Not Cancer Driver No 1 hippie, biogrid 74 60 2 2 0
TKFC TKFC Q3LXA3 Triokinase/FMN cyclase chr11 Not Cancer Driver No 1 hippie 66 91 14 14 2
TMEM70 TMEM70 Q9BUB7 Transmembrane protein 70, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 26 24 4 4 1
TMPRSS11E TMPRSS11E Q9UL52 Transmembrane protease serine 11E chr4 Not Cancer Driver No 1 hippie, biogrid 105 35 9 9 0
TNIP1_ENST00000522226 TNIP1 Q15025 TNFAIP3-interacting protein 1 chr5 Not Cancer Driver No 1 intact, hippie 85 625 83 83 0
TNPO3 TNPO3 Q9Y5L0 Transportin-3 chr7 Not Cancer Driver No 1 hippie, biogrid 122 12 1 1 1
TNS2_ENST00000314250 TNS2 Q63HR2 Tensin-2 chr12 Not Cancer Driver No 1 intact, hippie 132 799 63 63 0
TOMM22 TOMM22 Q9NS69 Mitochondrial import receptor subunit TOM22 homolog chr22 Not Cancer Driver No 1 hippie, biogrid 18 83 9 9 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 Not Cancer Driver No 1 intact, hippie 63 4 1 1 0
TRIM27 TRIM27 P14373 Zinc finger protein RFP chr6 Census Yes 1 intact, hippie 59 87 11 11 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 Not Cancer Driver No 1 hippie 82 87 10 10 3
TSFM_ENST00000454289 TSFM P43897 Elongation factor Ts, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 37 74 7 7 2
TSGA10_ENST00000355053 TSGA10 Q9BZW7 Testis-specific gene 10 protein chr2 Not Cancer Driver No 1 hippie 112 477 76 76 0
TYMP_ENST00000395680 TYMP P19971 Thymidine phosphorylase chr22 Not Cancer Driver No 1 hippie, biogrid 28 143 7 7 5
UQCRQ_ENST00000378665 UQCRQ O14949 Cytochrome b-c1 complex subunit 8 chr5 Not Cancer Driver No 1 hippie, biogrid 9 12 1 1 1
USO1_ENST00000514213 USO1 O60763 General vesicular transport factor p115 chr4 Not Cancer Driver No 1 hippie, biogrid 78 368 28 28 0
VAMP3 VAMP3 Q15836 Vesicle-associated membrane protein 3 chr1 Not Cancer Driver No 1 hippie, biogrid 11 17 1 1 0
VPS35 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 Not Cancer Driver No 1 hippie, biogrid 68 99 9 9 1
VRK1 VRK1 Q99986 Serine/threonine-protein kinase VRK1 chr14 Not Cancer Driver No 1 hippie, biogrid 52 80 9 9 0
VTA1 VTA1 Q9NP79 Vacuolar protein sorting-associated protein VTA1 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 49 152 25 25 0
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 Not Cancer Driver No 1 hippie, biogrid 65 62 10 10 0
ZBTB43_ENST00000449886 ZBTB43 O43298 Zinc finger and BTB domain-containing protein 43 chr9 Not Cancer Driver No 1 hippie 56 252 33 33 0
ZBTB8A ZBTB8A Q96BR9 Zinc finger and BTB domain-containing protein 8A chr1 Not Cancer Driver No 1 intact, hippie 47 205 24 24 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 67 23 0 0 3