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SYT2_ENST00000367268 ,SYT2 ,Q8N9I0
  • Uniprot Accession= Q8N9I0
  • Ensembl Transcript= ENST00000367268.4
  • Uniprot Name= SYT2
  • Name= Synaptotagmin-2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 24
  • Number of Interaction partner in biogrid: 94
  • Number of Interaction partner in hippie: 132
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
ACADL ACADL P28330 Long-chain specific acyl-CoA dehydrogenase, mitochondrial chr2 Not Cancer Driver No 3 intact, hippie, biogrid 63 51 3 3 0
ADNP ADNP Q9H2P0 Activity-dependent neuroprotector homeobox protein chr20 Not Cancer Driver No 1 hippie, biogrid 130 615 66 66 0
AFF3_ENST00000317233 AFF3 P51826 AF4/FMR2 family member 3 chr2 Census, Compendium Yes 1 hippie, biogrid 248 1019 206 206 6
AFF4 AFF4 Q9UHB7 AF4/FMR2 family member 4 chr5 Census Yes 1 hippie, biogrid 138 993 121 121 3
AHCYL1 AHCYL1 O43865 S-adenosylhomocysteine hydrolase-like protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 58 108 10 10 0
AHCYL2 AHCYL2 Q96HN2 Adenosylhomocysteinase 3 chr7 Not Cancer Driver No 1 hippie, biogrid 76 208 23 23 0
ANKRD17 ANKRD17 O75179 Ankyrin repeat domain-containing protein 17 chr4 Not Cancer Driver No 1 hippie, biogrid 312 1790 221 221 9
AP3B1 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 Not Cancer Driver No 1 hippie, biogrid 126 316 31 31 1
AP3B2_ENST00000261722 AP3B2 Q13367 AP-3 complex subunit beta-2 chr15 Not Cancer Driver No 1 hippie, biogrid 145 381 51 51 0
APBA2_ENST00000561069 APBA2 Q99767 Amyloid-beta A4 precursor protein-binding family A member 2 chr15 Not Cancer Driver No 1 hippie, biogrid 184 429 117 117 0
AQP10 AQP10 Q96PS8 Aquaporin-10 chr1 Not Cancer Driver No 1 intact, hippie 73 15 1 1 0
ARHGAP10 ARHGAP10 A1A4S6 Rho GTPase-activating protein 10 chr4 Not Cancer Driver No 1 hippie, biogrid 100 267 41 41 0
ARIH1 ARIH1 Q9Y4X5 E3 ubiquitin-protein ligase ARIH1 chr15 Not Cancer Driver No 1 hippie, biogrid 46 119 7 7 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 Not Cancer Driver No 1 hippie, biogrid 46 122 22 22 0
BNIP2_ENST00000607373 BNIP2 Q12982 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 chr15 Not Cancer Driver No 1 intact, hippie 28 144 18 18 0
BOD1 BOD1 Q96IK1 Biorientation of chromosomes in cell division protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 16 133 10 10 0
BOP1 BOP1 Q14137 Ribosome biogenesis protein BOP1 chr8 Not Cancer Driver No 1 hippie, biogrid 20 304 19 19 0
BRPF1_ENST00000457855 BRPF1 P55201 Peregrin chr3 Not Cancer Driver No 1 hippie, biogrid 148 753 95 95 2
C18orf25 C18orf25 Q96B23 Uncharacterized protein C18orf25 chr18 Not Cancer Driver No 1 hippie, biogrid 30 393 27 27 0
C1orf52 C1orf52 Q8N6N3 UPF0690 protein C1orf52 chr1 Not Cancer Driver No 1 hippie, biogrid 29 182 29 29 0
C2CD5_ENST00000333957 C2CD5 Q86YS7 C2 domain-containing protein 5 chr12 Not Cancer Driver No 1 hippie, biogrid 136 250 40 40 0
CAMKV CAMKV Q8NCB2 CaM kinase-like vesicle-associated protein chr3 Not Cancer Driver No 1 hippie, biogrid 87 226 30 30 0
CCDC167 CCDC167 Q9P0B6 Coiled-coil domain-containing protein 167 chr6 Not Cancer Driver No 1 intact, hippie 12 29 3 3 0
CD81 CD81 P60033 CD81 antigen chr11 Not Cancer Driver No 1 hippie 28 0 0 0 0
CDC34 CDC34 P49427 Ubiquitin-conjugating enzyme E2 R1 chr19 Not Cancer Driver No 1 hippie, biogrid 26 95 11 11 0
CENPB CENPB P07199 Major centromere autoantigen B chr20 Not Cancer Driver No 1 hippie, biogrid 64 374 39 39 0
CERS6_ENST00000305747 CERS6 Q6ZMG9 Ceramide synthase 6 chr2 Not Cancer Driver No 1 hippie, biogrid 54 32 10 10 0
CHD9_ENST00000398510 CHD9 Q3L8U1 Chromodomain-helicase-DNA-binding protein 9 chr16 Not Cancer Driver No 1 hippie, biogrid 301 1653 162 162 0
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 Census, Compendium Yes 1 hippie, biogrid 335 157 130 130 13
CLDN4 CLDN4 O14493 Claudin-4 chr7 Not Cancer Driver No 1 intact, hippie 40 0 0 0 0
CMTM3_ENST00000567572 CMTM3 Q96MX0 CKLF-like MARVEL transmembrane domain-containing protein 3 chr16 Not Cancer Driver No 1 intact, hippie 16 39 1 1 0
COPS2_ENST00000388901 COPS2 P61201 COP9 signalosome complex subunit 2 chr15 Not Cancer Driver No 1 hippie, biogrid 59 59 9 9 0
COPS3 COPS3 Q9UNS2 COP9 signalosome complex subunit 3 chr17 Not Cancer Driver No 1 hippie, biogrid 55 67 10 10 0
COPS4_ENST00000264389 COPS4 Q9BT78 COP9 signalosome complex subunit 4 chr4 Not Cancer Driver No 1 hippie, biogrid 50 13 0 0 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie, biogrid 36 32 7 7 0
COPS6 COPS6 Q7L5N1 COP9 signalosome complex subunit 6 chr7 Not Cancer Driver No 1 hippie, biogrid 38 30 6 6 0
COPS7A_ENST00000534947 COPS7A Q9UBW8 COP9 signalosome complex subunit 7a chr12 Not Cancer Driver No 1 hippie, biogrid 32 74 10 10 0
COPS7B_ENST00000410024 COPS7B Q9H9Q2 COP9 signalosome complex subunit 7b chr2 Not Cancer Driver No 1 hippie, biogrid 22 74 6 6 0
CTDP1 CTDP1 Q9Y5B0 RNA polymerase II subunit A C-terminal domain phosphatase chr18 Not Cancer Driver No 1 hippie, biogrid 121 624 87 87 0
CTR9 CTR9 Q6PD62 RNA polymerase-associated protein CTR9 homolog chr11 Not Cancer Driver No 1 hippie, biogrid 164 385 48 48 0
CUL4A CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 hippie, biogrid 64 102 2 2 0
CUL4B CUL4B Q13620 Cullin-4B chrX Not Cancer Driver No 1 hippie, biogrid 138 207 38 38 2
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 188 372 41 41 3
CWC22 CWC22 Q9HCG8 Pre-mRNA-splicing factor CWC22 homolog chr2 Not Cancer Driver No 1 hippie, biogrid 104 494 56 56 0
CWC27 CWC27 Q6UX04 Spliceosome-associated protein CWC27 homolog chr5 Not Cancer Driver No 1 hippie, biogrid 60 345 43 43 0
CYBC1_ENST00000577732 CYBC1 Q9BQA9 Cytochrome b-245 chaperone 1 chr17 Not Cancer Driver No 1 hippie 22 17 2 2 0
DACH1_ENST00000619232 DACH1 Q9UI36 Dachshund homolog 1 chr13 Not Cancer Driver No 1 hippie, biogrid 157 641 134 134 0
DCAF16 DCAF16 Q9NXF7 DDB1- and CUL4-associated factor 16 chr4 Not Cancer Driver No 1 hippie, biogrid 30 67 9 9 0
DCAF5 DCAF5 Q96JK2 DDB1- and CUL4-associated factor 5 chr14 Not Cancer Driver No 1 hippie, biogrid 119 521 80 80 0
EAF2 EAF2 Q96CJ1 ELL-associated factor 2 chr3 Not Cancer Driver No 1 hippie, biogrid 31 199 22 22 0
EIF2B1 EIF2B1 Q14232 Translation initiation factor eIF-2B subunit alpha chr12 Not Cancer Driver No 1 hippie, biogrid 33 0 0 0 2
EIF2B2 EIF2B2 P49770 Translation initiation factor eIF-2B subunit beta chr14 Not Cancer Driver No 1 hippie, biogrid 40 83 11 11 9
EIF2B3 EIF2B3 Q9NR50 Translation initiation factor eIF-2B subunit gamma chr1 Not Cancer Driver No 1 hippie, biogrid 54 28 9 9 5
EIF2B4_ENST00000347454 EIF2B4 Q9UI10 Translation initiation factor eIF-2B subunit delta chr2 Not Cancer Driver No 1 hippie, biogrid 57 212 29 29 7
EIF2B5 EIF2B5 Q13144 Translation initiation factor eIF-2B subunit epsilon chr3 Not Cancer Driver No 1 hippie, biogrid 76 179 16 16 29
EPB41L5 EPB41L5 Q9HCM4 Band 4.1-like protein 5 chr2 Not Cancer Driver No 1 hippie, biogrid 97 312 45 45 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 Not Cancer Driver No 1 hippie, biogrid 125 250 28 28 0
EXOG EXOG Q9Y2C4 Nuclease EXOG, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 42 52 1 1 0
FA2H FA2H Q7L5A8 Fatty acid 2-hydroxylase chr16 Not Cancer Driver No 1 intact, hippie 33 73 0 0 3
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 Census, Compendium Yes 1 hippie, biogrid 152 230 43 43 74
FIBP FIBP O43427 Acidic fibroblast growth factor intracellular-binding protein chr11 Not Cancer Driver No 1 hippie, biogrid 32 15 2 2 0
FUNDC2 FUNDC2 Q9BWH2 FUN14 domain-containing protein 2 chrX Not Cancer Driver No 1 hippie 28 34 3 3 0
GPATCH2 GPATCH2 Q9NW75 G patch domain-containing protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 86 521 86 86 0
GPATCH8 GPATCH8 Q9UKJ3 G patch domain-containing protein 8 chr17 Not Cancer Driver No 1 hippie, biogrid 210 1325 188 188 0
GPBP1L1 GPBP1L1 Q9HC44 Vasculin-like protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 45 456 44 44 0
HDGFL2 HDGFL2 Q7Z4V5 Hepatoma-derived growth factor-related protein 2 chr19 Not Cancer Driver No 1 hippie 59 622 57 57 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HTT HTT P42858 Huntingtin chr4 Not Cancer Driver No 2 intact, hippie 336 666 69 69 2
IFT46_ENST00000264021 IFT46 Q9NQC8 Intraflagellar transport protein 46 homolog chr11 Not Cancer Driver No 1 hippie, biogrid 38 164 20 20 0
ITGAM_ENST00000287497 ITGAM P11215 Integrin alpha-M chr16 Not Cancer Driver No 1 intact, hippie 191 133 12 12 0
JMJD6_ENST00000397625 JMJD6 Q6NYC1 Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 chr17 Not Cancer Driver No 1 hippie, biogrid 51 133 21 21 0
KANK1_ENST00000382303 KANK1 Q14678 KN motif and ankyrin repeat domain-containing protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 183 804 100 100 0
KLHL3 KLHL3 Q9UH77 Kelch-like protein 3 chr5 Not Cancer Driver No 1 hippie 67 34 9 9 32
LAT_ENST00000360872 LAT O43561 Linker for activation of T-cells family member 1 chr16 Not Cancer Driver No 1 hippie 37 213 29 29 0
LENG8 LENG8 Q96PV6 Leukocyte receptor cluster member 8 chr19 Not Cancer Driver No 1 hippie, biogrid 137 515 97 97 0
LEO1 LEO1 Q8WVC0 RNA polymerase-associated protein LEO1 chr15 Not Cancer Driver No 1 hippie, biogrid 74 611 69 69 0
MADD MADD Q8WXG6 MAP kinase-activating death domain protein chr11 Not Cancer Driver No 1 hippie, biogrid 207 723 81 81 4
MALL MALL Q13021 MAL-like protein chr2 Not Cancer Driver No 1 hippie 20 0 0 0 0
MAP4K4_ENST00000347699 MAP4K4 O95819 Mitogen-activated protein kinase kinase kinase kinase 4 chr2 Not Cancer Driver No 1 hippie, biogrid 143 649 55 55 0
MIER1_ENST00000355356 MIER1 Q8N108 Mesoderm induction early response protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 64 373 45 45 0
MIP MIP P30301 Lens fiber major intrinsic protein chr12 Not Cancer Driver No 1 intact, hippie 71 20 1 1 6
MLLT1 MLLT1 Q03111 Protein ENL chr19 Census, Compendium Yes 1 hippie, biogrid 68 413 43 43 0
MLLT3 MLLT3 P42568 Protein AF-9 chr9 Census, Compendium Yes 1 hippie, biogrid 69 414 58 58 0
MTHFR_ENST00000376590 MTHFR P42898 Methylenetetrahydrofolate reductase chr1 Not Cancer Driver No 1 hippie, biogrid 95 125 22 22 53
NAA15 NAA15 Q9BXJ9 N-alpha-acetyltransferase 15, NatA auxiliary subunit chr4 Not Cancer Driver No 1 hippie, biogrid 95 115 17 17 0
NAF1 NAF1 Q96HR8 H/ACA ribonucleoprotein complex non-core subunit NAF1 chr4 Not Cancer Driver No 1 hippie, biogrid 61 386 44 44 0
NAP1L3 NAP1L3 Q99457 Nucleosome assembly protein 1-like 3 chrX Not Cancer Driver No 1 hippie, biogrid 116 326 78 78 0
NAPB_ENST00000377026 NAPB Q9H115 Beta-soluble NSF attachment protein chr20 Not Cancer Driver No 1 intact, hippie 30 29 2 2 0
NOLC1_ENST00000605788 NOLC1 Q14978 Nucleolar and coiled-body phosphoprotein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 74 662 69 69 0
NRXN1_ENST00000406316 NRXN1 Q9ULB1 Neurexin-1 chr2 Not Cancer Driver No 1 hippie 593 301 110 110 0
ORMDL3_ENST00000304046 ORMDL3 Q8N138 ORM1-like protein 3 chr17 Not Cancer Driver No 1 intact, hippie 22 9 1 1 0
PAF1 PAF1 Q8N7H5 RNA polymerase II-associated factor 1 homolog chr19 Not Cancer Driver No 1 hippie, biogrid 77 378 56 56 0
PIP4K2C_ENST00000540759 PIP4K2C Q8TBX8 Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma chr12 Not Cancer Driver No 1 hippie, biogrid 62 111 23 23 0
PKD2 PKD2 Q13563 Polycystin-2 chr4 Not Cancer Driver No 1 intact 113 375 35 35 10
PLPP4 PLPP4 Q5VZY2 Phospholipid phosphatase 4 chr10 Not Cancer Driver No 1 intact, hippie 59 14 1 1 0
PMP22_ENST00000612492 PMP22 Q01453 Peripheral myelin protein 22 chr17 Not Cancer Driver No 1 intact, hippie 20 0 0 0 37
PPM1G PPM1G O15355 Protein phosphatase 1G chr2 Not Cancer Driver No 1 hippie, biogrid 51 359 39 39 0
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 Compendium Yes 1 hippie 118 246 34 34 0
PRPF40A PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 hippie, biogrid 83 694 57 57 0
RAD18 RAD18 Q9NS91 E3 ubiquitin-protein ligase RAD18 chr3 Not Cancer Driver No 1 hippie, biogrid 59 328 43 43 0
RANBP10 RANBP10 Q6VN20 Ran-binding protein 10 chr16 Not Cancer Driver No 1 hippie, biogrid 91 297 50 50 0
RBM25 RBM25 P49756 RNA-binding protein 25 chr14 Not Cancer Driver No 1 hippie, biogrid 124 549 88 88 0
ROR1 ROR1 Q01973 Inactive tyrosine-protein kinase transmembrane receptor ROR1 chr1 Not Cancer Driver No 1 hippie, biogrid 144 280 43 43 1
RTF1 RTF1 Q92541 RNA polymerase-associated protein RTF1 homolog chr15 Not Cancer Driver No 1 hippie, biogrid 83 568 67 67 0
SETD1A SETD1A O15047 Histone-lysine N-methyltransferase SETD1A chr16 Not Cancer Driver No 1 hippie, biogrid 223 1327 188 188 5
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 Not Cancer Driver No 1 hippie, biogrid 70 435 31 31 0
SLC30A8 SLC30A8 Q8IWU4 Zinc transporter 8 chr8 Not Cancer Driver No 1 intact, hippie 115 25 9 9 0
SLC35A1 SLC35A1 P78382 CMP-sialic acid transporter chr6 Not Cancer Driver No 1 intact, hippie 23 0 0 0 0
SLC35A4_ENST00000323146 SLC35A4 Q96G79 Probable UDP-sugar transporter protein SLC35A4 chr5 Not Cancer Driver No 1 intact, hippie 38 13 0 0 0
SMG5 SMG5 Q9UPR3 Nonsense-mediated mRNA decay factor SMG5 chr1 Not Cancer Driver No 1 hippie, biogrid 132 295 51 51 0
SMG7_ENST00000347615 SMG7 Q92540 Nonsense-mediated mRNA decay factor SMG7 chr1 Not Cancer Driver No 1 hippie, biogrid 134 664 82 82 0
STON2_ENST00000267540 STON2 Q8WXE9 Stonin-2 chr14 Not Cancer Driver No 1 hippie 153 449 77 77 0
SYNCRIP SYNCRIP O60506 Heterogeneous nuclear ribonucleoprotein Q chr6 Not Cancer Driver No 1 hippie 93 285 39 39 0
SYT1_ENST00000393240 SYT1 P21579 Synaptotagmin-1 chr12 Not Cancer Driver No 2 hippie, biogrid 104 103 36 36 5
SYT5 SYT5 O00445 Synaptotagmin-5 chr19 Not Cancer Driver No 1 hippie, biogrid 60 110 11 11 0
TF TF P02787 Serotransferrin chr3 Not Cancer Driver No 1 hippie 135 21 5 5 2
TGOLN2_ENST00000377386 TGOLN2 O43493 Trans-Golgi network integral membrane protein 2 chr2 Not Cancer Driver No 1 intact, hippie 51 399 46 46 0
THSD7B THSD7B Q9C0I4 Thrombospondin type-1 domain-containing protein 7B chr2 Not Cancer Driver No 1 intact, hippie 652 94 19 19 0
TMEM107_ENST00000437139 TMEM107 Q6UX40 Transmembrane protein 107 chr17 Not Cancer Driver No 1 intact, hippie 12 0 0 0 1
TMEM229B TMEM229B Q8NBD8 Transmembrane protein 229B chr14 Not Cancer Driver No 1 intact, hippie 27 0 0 0 0
TRMT10A_ENST00000394876 TRMT10A Q8TBZ6 tRNA methyltransferase 10 homolog A chr4 Not Cancer Driver No 1 hippie, biogrid 49 182 28 28 1
TSPO2 TSPO2 Q5TGU0 Translocator protein 2 chr6 Not Cancer Driver No 1 intact, hippie 23 7 3 3 0
UBE2O UBE2O Q9C0C9 (E3-independent) E2 ubiquitin-conjugating enzyme chr17 Not Cancer Driver No 1 hippie, biogrid 129 716 68 68 0
UBE2Q1 UBE2Q1 Q7Z7E8 Ubiquitin-conjugating enzyme E2 Q1 chr1 Not Cancer Driver No 1 hippie, biogrid 45 173 16 16 0
UBE2R2 UBE2R2 Q712K3 Ubiquitin-conjugating enzyme E2 R2 chr9 Not Cancer Driver No 1 hippie, biogrid 28 104 15 15 0
UBXN7 UBXN7 O94888 UBX domain-containing protein 7 chr3 Not Cancer Driver No 1 hippie, biogrid 65 327 39 39 0
UTP25 UTP25 Q68CQ4 U3 small nucleolar RNA-associated protein 25 homolog chr1 Not Cancer Driver No 1 hippie 116 277 28 28 0
VAMP4 VAMP4 O75379 Vesicle-associated membrane protein 4 chr1 Not Cancer Driver No 1 intact, hippie 9 80 6 6 0
VLDLR VLDLR P98155 Very low-density lipoprotein receptor chr9 Not Cancer Driver No 1 hippie, biogrid 90 55 3 3 0
VTI1B VTI1B Q9UEU0 Vesicle transport through interaction with t-SNAREs homolog 1B chr14 Not Cancer Driver No 1 hippie, biogrid 25 192 20 20 0
WDR55 WDR55 Q9H6Y2 WD repeat-containing protein 55 chr5 Not Cancer Driver No 1 hippie, biogrid 47 102 7 7 0
WDR70 WDR70 Q9NW82 WD repeat-containing protein 70 chr5 Not Cancer Driver No 1 hippie, biogrid 97 363 57 57 0
WNK1_ENST00000315939 WNK1 Q9H4A3 Serine/threonine-protein kinase WNK1 chr12 Not Cancer Driver No 1 hippie 278 1959 223 223 0