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SYNC ,SYNC ,Q9H7C4
  • Uniprot Accession= Q9H7C4
  • Ensembl Transcript= ENST00000409190.7
  • Uniprot Name= SYNC
  • Name= Syncoilin
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 35
  • Number of Interaction partner in biogrid: 53
  • Number of Interaction partner in hippie: 67
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTA1 ACTA1 P68133 Actin, alpha skeletal muscle chr1 Not Cancer Driver No 1 intact, hippie 70 48 14 14 84
APC APC P25054 Adenomatous polyposis coli protein chr5 Census, Compendium Yes 2 intact, hippie, biogrid 412 2406 345 345 22
ARHGEF6 ARHGEF6 Q15052 Rho guanine nucleotide exchange factor 6 chrX Not Cancer Driver No 2 hippie, biogrid 158 223 45 45 0
ARHGEF7 ARHGEF7 Q14155 Rho guanine nucleotide exchange factor 7 chr13 Not Cancer Driver No 2 intact, hippie, biogrid 106 301 39 39 0
ATP1A3_ENST00000302102 ATP1A3 P13637 Sodium/potassium-transporting ATPase subunit alpha-3 chr19 Not Cancer Driver No 1 hippie 200 115 29 29 31
BCR BCR P11274 Breakpoint cluster region protein chr22 Census, Compendium Yes 1 hippie, biogrid 146 603 69 69 0
BICDL2 BICDL2 A1A5D9 BICD family-like cargo adapter 2 chr16 Not Cancer Driver No 1 hippie 50 446 49 49 0
CALCOCO2_ENST00000258947 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 42 212 19 19 0
CCDC102A CCDC102A Q96A19 Coiled-coil domain-containing protein 102A chr16 Not Cancer Driver No 2 intact, hippie, biogrid 51 526 43 43 0
CCDC136 CCDC136 Q96JN2 Coiled-coil domain-containing protein 136 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 150 818 114 114 0
CEP250 CEP250 Q9BV73 Centrosome-associated protein CEP250 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 250 1859 195 195 0
CEP55 CEP55 Q53EZ4 Centrosomal protein of 55 kDa chr10 Not Cancer Driver No 2 hippie, biogrid 59 264 26 26 0
CPNE2_ENST00000535318 CPNE2 Q96FN4 Copine-2 chr16 Not Cancer Driver No 1 hippie, biogrid 62 32 4 4 0
DDX39A DDX39A O00148 ATP-dependent RNA helicase DDX39A chr19 Not Cancer Driver No 1 hippie, biogrid 44 37 2 2 0
DES DES P17661 Desmin chr2 Not Cancer Driver No 3 intact, hippie, biogrid 71 264 41 41 35
DTNA_ENST00000444659 DTNA Q9Y4J8 Dystrobrevin alpha chr18 Not Cancer Driver No 1 hippie 162 412 86 86 0
DUSP23_ENST00000368109 DUSP23 Q9BVJ7 Dual specificity protein phosphatase 23 chr1 Not Cancer Driver No 1 hippie, biogrid 6 13 1 1 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
EPS15 EPS15 P42566 Epidermal growth factor receptor substrate 15 chr1 Census, Compendium Yes 1 hippie, biogrid 106 543 66 66 0
FGFR1OP2 FGFR1OP2 Q9NVK5 FGFR1 oncogene partner 2 chr12 Not Cancer Driver No 1 hippie, biogrid 25 185 21 21 0
GAN GAN Q9H2C0 Gigaxonin chr16 Not Cancer Driver No 2 hippie, biogrid 74 33 6 6 19
GCC2 GCC2 Q8IWJ2 GRIP and coiled-coil domain-containing protein 2 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 178 999 113 113 0
GEMIN5 GEMIN5 Q8TEQ6 Gem-associated protein 5 chr5 Not Cancer Driver No 1 intact, hippie 157 419 54 54 5
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 Not Cancer Driver No 3 intact, hippie, biogrid 65 288 42 42 62
GIT1_ENST00000225394 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 67 434 42 42 0
GIT2 GIT2 Q14161 ARF GTPase-activating protein GIT2 chr12 Not Cancer Driver No 2 hippie, biogrid 83 492 47 47 0
GOLGA3_ENST00000450791 GOLGA3 Q08378 Golgin subfamily A member 3 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 221 1272 189 189 0
GOLGA5 GOLGA5 Q8TBA6 Golgin subfamily A member 5 chr14 Census Yes 2 intact, hippie, biogrid 89 591 62 62 0
HSPE1 HSPE1 P61604 10 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 8 3 0 0 0
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX Not Cancer Driver No 2 hippie, biogrid 6 301 6 6 22
INA INA Q16352 Alpha-internexin chr10 Not Cancer Driver No 2 intact, hippie, biogrid 62 256 43 43 0
KIF15 KIF15 Q9NS87 Kinesin-like protein KIF15 chr3 Not Cancer Driver No 2 hippie, biogrid 148 819 93 93 0
KIF1B_ENST00000377086 KIF1B O60333 Kinesin-like protein KIF1B chr1 Not Cancer Driver No 1 intact, hippie 253 633 106 106 1
KLHL42 KLHL42 Q9P2K6 Kelch-like protein 42 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 48 57 4 4 0
KRT14 KRT14 P02533 Keratin, type I cytoskeletal 14 chr17 Not Cancer Driver No 1 hippie, biogrid 76 183 31 31 40
KRT16 KRT16 P08779 Keratin, type I cytoskeletal 16 chr17 Not Cancer Driver No 1 hippie, biogrid 83 152 28 28 16
KRT23 KRT23 Q9C075 Keratin, type I cytoskeletal 23 chr17 Not Cancer Driver No 1 hippie, biogrid 69 259 47 47 0
KRT27 KRT27 Q7Z3Y8 Keratin, type I cytoskeletal 27 chr17 Not Cancer Driver No 1 hippie, biogrid 80 142 28 28 0
LMNA LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie, biogrid 68 544 49 49 131
MAGEE1 MAGEE1 Q9HCI5 Melanoma-associated antigen E1 chrX Not Cancer Driver No 1 hippie, biogrid 218 528 123 123 0
MAML2 MAML2 Q8IZL2 Mastermind-like protein 2 chr11 Census, Compendium Yes 1 hippie, biogrid 146 1156 146 146 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 104 333 66 66 6
MCC_ENST00000302475 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 2 intact, hippie, biogrid 136 589 92 92 0
NDC80 NDC80 O14777 Kinetochore protein NDC80 homolog chr18 Not Cancer Driver No 2 hippie, biogrid 80 313 45 45 0
NEFL NEFL P07196 Neurofilament light polypeptide chr8 Not Cancer Driver No 2 hippie, biogrid 92 285 39 39 12
NEFM NEFM P07197 Neurofilament medium polypeptide chr8 Not Cancer Driver No 2 intact, hippie, biogrid 182 767 147 147 0
NES NES P48681 Nestin chr1 Not Cancer Driver No 1 intact, hippie, biogrid 271 1474 253 253 0
PECAM1 PECAM1 P16284 Platelet endothelial cell adhesion molecule chr17 Not Cancer Driver No 1 hippie 2 153 2 2 0
PLD1 PLD1 Q13393 Phospholipase D1 chr3 Not Cancer Driver No 1 intact, hippie 181 133 32 32 1
PPA2 PPA2 Q9H2U2 Inorganic pyrophosphatase 2, mitochondrial chr4 Not Cancer Driver No 2 intact, hippie, biogrid 49 71 9 9 9
PPL PPL O60437 Periplakin chr16 Not Cancer Driver No 1 hippie, biogrid 219 1133 133 133 0
PRPH PRPH P41219 Peripherin chr12 Not Cancer Driver No 2 intact, hippie, biogrid 37 239 20 20 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 intact, hippie 32 65 15 15 0
RABEP1 RABEP1 Q15276 Rab GTPase-binding effector protein 1 chr17 Census, Compendium Yes 2 hippie, biogrid 81 520 57 57 0
RNF123 RNF123 Q5XPI4 E3 ubiquitin-protein ligase RNF123 chr3 Not Cancer Driver No 1 hippie 167 220 28 28 0
RUFY1 RUFY1 Q96T51 RUN and FYVE domain-containing protein 1 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 79 356 40 40 0
SLMAP SLMAP Q14BN4 Sarcolemmal membrane-associated protein chr3 Not Cancer Driver No 2 intact, hippie, biogrid 77 464 38 38 0
SPDL1 SPDL1 Q96EA4 Protein Spindly chr5 Not Cancer Driver No 1 hippie, biogrid 75 342 43 43 0
SYNM SYNM O15061 Synemin chr15 Not Cancer Driver No 2 hippie, biogrid 156 1244 131 131 0
TAB1 TAB1 Q15750 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chr22 Not Cancer Driver No 2 intact, hippie, biogrid 81 232 34 34 0
THAP11 THAP11 Q96EK4 THAP domain-containing protein 11 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 23 207 17 17 0
TJAP1 TJAP1 Q5JTD0 Tight junction-associated protein 1 chr6 Not Cancer Driver No 2 hippie, biogrid 74 442 65 65 0
TNIP1_ENST00000522226 TNIP1 Q15025 TNFAIP3-interacting protein 1 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 85 625 83 83 0
TRAF3IP1 TRAF3IP1 Q8TDR0 TRAF3-interacting protein 1 chr2 Not Cancer Driver No 1 intact, hippie 75 507 60 60 4
UACA UACA Q9BZF9 Uveal autoantigen with coiled-coil domains and ankyrin repeats chr15 Not Cancer Driver No 2 intact, hippie, biogrid 177 863 101 101 0
VIM_ENST00000224237 VIM P08670 Vimentin chr10 Not Cancer Driver No 3 intact, hippie, biogrid 84 316 57 57 1
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 Not Cancer Driver No 1 intact, hippie 105 203 10 10 39