Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AAGAB | AAGAB | Q6PD74 | Alpha- and gamma-adaptin-binding protein p34 | chr15 | Not Cancer Driver | No | 3 | hippie, biogrid | 30 | 151 | 13 | 13 | 0 |
| AGR2 | AGR2 | O95994 | Anterior gradient protein 2 homolog | chr7 | Not Cancer Driver | No | 1 | hippie | 23 | 20 | 2 | 2 | 0 |
| ASPH | ASPH | Q12797 | Aspartyl/asparaginyl beta-hydroxylase | chr8 | Not Cancer Driver | No | 2 | hippie, biogrid | 109 | 373 | 53 | 53 | 1 |
| ATG2A | ATG2A | Q2TAZ0 | Autophagy-related protein 2 homolog A | chr11 | Not Cancer Driver | No | 1 | hippie | 228 | 887 | 124 | 124 | 0 |
| C11orf52 | C11orf52 | Q96A22 | Uncharacterized protein C11orf52 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 108 | 12 | 12 | 0 |
| CD81 | CD81 | P60033 | CD81 antigen | chr11 | Not Cancer Driver | No | 1 | hippie | 28 | 0 | 0 | 0 | 0 |
| CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 39 | 23 | 2 | 2 | 1 |
| CELA2B | CELA2B | P08218 | Chymotrypsin-like elastase family member 2B | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 3 | 0 | 0 | 0 |
| DDX20 | DDX20 | Q9UHI6 | Probable ATP-dependent RNA helicase DDX20 | chr1 | Not Cancer Driver | No | 1 | hippie | 89 | 299 | 33 | 33 | 0 |
| DIS3 | DIS3 | Q9Y2L1 | Exosome complex exonuclease RRP44 | chr13 | Compendium | Yes | 1 | hippie, biogrid | 121 | 235 | 32 | 32 | 0 |
| DNAJC5 | DNAJC5 | Q9H3Z4 | DnaJ homolog subfamily C member 5 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 46 | 6 | 6 | 1 |
| EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 13 | 0 | 0 | 0 |
| EMC4 | EMC4 | Q5J8M3 | ER membrane protein complex subunit 4 | chr15 | Not Cancer Driver | No | 1 | hippie | 15 | 17 | 2 | 2 | 0 |
| FN1 | FN1 | P02751 | Fibronectin | chr2 | Compendium | Yes | 1 | hippie | 394 | 1243 | 185 | 185 | 8 |
| GEMIN2 | GEMIN2 | O14893 | Gem-associated protein 2 | chr14 | Not Cancer Driver | No | 1 | hippie | 39 | 99 | 6 | 6 | 0 |
| GEMIN4 | GEMIN4 | P57678 | Gem-associated protein 4 | chr17 | Not Cancer Driver | No | 1 | hippie | 101 | 24 | 1 | 1 | 0 |
| GEMIN5 | GEMIN5 | Q8TEQ6 | Gem-associated protein 5 | chr5 | Not Cancer Driver | No | 1 | hippie | 157 | 419 | 54 | 54 | 5 |
| GJD4 | GJD4 | Q96KN9 | Gap junction delta-4 protein | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 44 | 164 | 8 | 8 | 0 |
| GPR141 | GPR141 | Q7Z602 | Probable G-protein coupled receptor 141 | chr7 | Not Cancer Driver | No | 2 | hippie, biogrid | 105 | 6 | 1 | 1 | 0 |
| GPRC5B_ENST00000569479 | GPRC5B | Q9NZH0 | G-protein coupled receptor family C group 5 member B | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 82 | 75 | 19 | 19 | 0 |
| GPRC5D | GPRC5D | Q9NZD1 | G-protein coupled receptor family C group 5 member D | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 32 | 1 | 1 | 0 |
| HNRNPU | HNRNPU | Q00839 | Heterogeneous nuclear ribonucleoprotein U | chr1 | Not Cancer Driver | No | 1 | hippie | 77 | 504 | 45 | 45 | 0 |
| HRAS | HRAS | P01112 | GTPase HRas | chr11 | Census, Compendium | Yes | 1 | hippie, biogrid | 107 | 16 | 4 | 4 | 18 |
| ICMT | ICMT | O60725 | Protein-S-isoprenylcysteine O-methyltransferase | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 24 | 0 | 0 | 0 | 0 |
| IL1B | IL1B | P01584 | Interleukin-1 beta | chr2 | Not Cancer Driver | No | 1 | hippie | 39 | 16 | 3 | 3 | 0 |
| INF2 | INF2 | Q27J81 | Inverted formin-2 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 120 | 635 | 49 | 49 | 30 |
| IPPK | IPPK | Q9H8X2 | Inositol-pentakisphosphate 2-kinase | chr9 | Not Cancer Driver | No | 2 | hippie, biogrid | 55 | 43 | 3 | 3 | 0 |
| KCTD10 | KCTD10 | Q9H3F6 | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 | chr12 | Not Cancer Driver | No | 1 | hippie | 68 | 73 | 19 | 19 | 0 |
| KDSR | KDSR | Q06136 | 3-ketodihydrosphingosine reductase | chr18 | Census | Yes | 1 | hippie, biogrid | 31 | 35 | 4 | 4 | 1 |
| KRAS | KRAS | P01116 | GTPase KRas | chr12 | Census, Compendium | Yes | 2 | hippie, biogrid | 788 | 7 | 2 | 2 | 27 |
| LAPTM5 | LAPTM5 | Q13571 | Lysosomal-associated transmembrane protein 5 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 16 | 6 | 6 | 0 |
| LGALS9 | LGALS9 | O00182 | Galectin-9 | chr17 | Not Cancer Driver | No | 1 | hippie | 54 | 65 | 16 | 16 | 0 |
| LMBR1L | LMBR1L | Q6UX01 | Protein LMBR1L | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 4 | 0 | 0 | 0 |
| LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 519 | 90 | 17 | 17 | 23 |
| LYN | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | Census | Yes | 1 | hippie, biogrid | 95 | 84 | 12 | 12 | 0 |
| MTMR7 | MTMR7 | Q9Y216 | Myotubularin-related protein 7 | chr8 | Not Cancer Driver | No | 1 | hippie | 98 | 160 | 26 | 26 | 0 |
| NAPA | NAPA | P54920 | Alpha-soluble NSF attachment protein | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 11 | 0 | 0 | 0 |
| NIN | NIN | Q8N4C6 | Ninein | chr14 | Census, Compendium | Yes | 1 | hippie | 239 | 1392 | 164 | 164 | 2 |
| NRAS | NRAS | P01111 | GTPase NRas | chr1 | Census, Compendium | Yes | 1 | hippie, biogrid | 284 | 10 | 0 | 0 | 14 |
| NRSN1 | NRSN1 | Q8IZ57 | Neurensin-1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 17 | 9 | 9 | 0 |
| NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
| PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
| PLPP4 | PLPP4 | Q5VZY2 | Phospholipid phosphatase 4 | chr10 | Not Cancer Driver | No | 1 | hippie | 59 | 14 | 1 | 1 | 0 |
| PLPPR1_ENST00000395056 | PLPPR1 | Q8TBJ4 | Phospholipid phosphatase-related protein type 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 78 | 34 | 16 | 16 | 0 |
| PMAIP1 | PMAIP1 | Q13794 | Phorbol-12-myristate-13-acetate-induced protein 1 | chr18 | Not Cancer Driver | No | 1 | hippie | 2 | 23 | 1 | 1 | 0 |
| PRKCA | PRKCA | P17252 | Protein kinase C alpha type | chr17 | Not Cancer Driver | No | 1 | hippie | 94 | 154 | 22 | 22 | 0 |
| PSMD14 | PSMD14 | O00487 | 26S proteasome non-ATPase regulatory subunit 14 | chr2 | Not Cancer Driver | No | 1 | hippie | 23 | 67 | 6 | 6 | 0 |
| PTGES3_ENST00000262033 | PTGES3 | Q15185 | Prostaglandin E synthase 3 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 52 | 3 | 3 | 0 |
| RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | Census, Compendium | Yes | 1 | hippie | 66 | 2 | 1 | 1 | 6 |
| RAC2 | RAC2 | P15153 | Ras-related C3 botulinum toxin substrate 2 | chr22 | Not Cancer Driver | No | 1 | hippie | 31 | 0 | 0 | 0 | 2 |
| RAC3 | RAC3 | P60763 | Ras-related C3 botulinum toxin substrate 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 4 |
| RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | Census, Compendium | Yes | 1 | hippie | 99 | 46 | 13 | 13 | 2 |
| RHOB | RHOB | P62745 | Rho-related GTP-binding protein RhoB | chr2 | Not Cancer Driver | No | 2 | hippie, biogrid | 52 | 19 | 2 | 2 | 0 |
| RHOC_ENST00000369642 | RHOC | P08134 | Rho-related GTP-binding protein RhoC | chr1 | Not Cancer Driver | No | 1 | hippie | 30 | 53 | 7 | 7 | 0 |
| RHOD | RHOD | O00212 | Rho-related GTP-binding protein RhoD | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 10 | 0 | 0 | 0 |
| RHOF | RHOF | Q9HBH0 | Rho-related GTP-binding protein RhoF | chr12 | Not Cancer Driver | No | 1 | hippie | 18 | 10 | 0 | 0 | 0 |
| RHOG_ENST00000396978 | RHOG | P84095 | Rho-related GTP-binding protein RhoG | chr11 | Not Cancer Driver | No | 1 | hippie | 26 | 22 | 5 | 5 | 0 |
| RHOH_ENST00000617441 | RHOH | Q15669 | Rho-related GTP-binding protein RhoH | chr4 | Census | Yes | 1 | hippie | 41 | 12 | 3 | 3 | 0 |
| RHOJ | RHOJ | Q9H4E5 | Rho-related GTP-binding protein RhoJ | chr14 | Not Cancer Driver | No | 1 | hippie | 39 | 0 | 0 | 0 | 0 |
| RHOQ | RHOQ | P17081 | Rho-related GTP-binding protein RhoQ | chr2 | Not Cancer Driver | No | 1 | hippie | 25 | 0 | 0 | 0 | 0 |
| RHOU | RHOU | Q7L0Q8 | Rho-related GTP-binding protein RhoU | chr1 | Not Cancer Driver | No | 1 | hippie | 34 | 63 | 6 | 6 | 0 |
| RNF149 | RNF149 | Q8NC42 | E3 ubiquitin-protein ligase RNF149 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 102 | 10 | 10 | 0 |
| RPL3 | RPL3 | P39023 | 60S ribosomal protein L3 | chr22 | Not Cancer Driver | No | 1 | hippie | 34 | 79 | 3 | 3 | 0 |
| RPS6KA2_ENST00000265678 | RPS6KA2 | Q15349 | Ribosomal protein S6 kinase alpha-2 | chr6 | Not Cancer Driver | No | 1 | hippie | 133 | 91 | 15 | 15 | 0 |
| S1PR1 | S1PR1 | P21453 | Sphingosine 1-phosphate receptor 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 86 | 29 | 6 | 6 | 0 |
| SH3BGRL3 | SH3BGRL3 | Q9H299 | SH3 domain-binding glutamic acid-rich-like protein 3 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 9 | 34 | 3 | 3 | 0 |
| SLC35F2 | SLC35F2 | Q8IXU6 | Solute carrier family 35 member F2 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 12 | 0 | 0 | 0 |
| SMN1_ENST00000503079 | SMN1 | Q16637-2 | Isoform SMN-delta5 of Survival motor neuron protein | chr5 | Not Cancer Driver | No | 1 | hippie | 2 | 181 | 2 | 2 | 0 |
| SNAP23 | SNAP23 | O00161 | Synaptosomal-associated protein 23 | chr15 | Not Cancer Driver | No | 1 | hippie | 18 | 179 | 16 | 16 | 0 |
| SNRPB | SNRPB | P14678 | Small nuclear ribonucleoprotein-associated proteins B and B' | chr20 | Not Cancer Driver | No | 1 | hippie | 39 | 182 | 34 | 34 | 4 |
| SNRPD2_ENST00000588301 | SNRPD2 | P62316 | Small nuclear ribonucleoprotein Sm D2 | chr19 | Not Cancer Driver | No | 1 | hippie | 19 | 67 | 12 | 12 | 0 |
| SNRPD3 | SNRPD3 | P62318 | Small nuclear ribonucleoprotein Sm D3 | chr22 | Not Cancer Driver | No | 1 | hippie | 20 | 43 | 13 | 13 | 0 |
| SNTG1 | SNTG1 | Q9NSN8 | Gamma-1-syntrophin | chr8 | Not Cancer Driver | No | 1 | hippie | 204 | 3 | 1 | 1 | 0 |
| STAU1 | STAU1 | O95793 | Double-stranded RNA-binding protein Staufen homolog 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 77 | 456 | 63 | 63 | 0 |
| STRA6_ENST00000323940 | STRA6 | Q9BX79 | Receptor for retinol uptake STRA6 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 77 | 84 | 14 | 14 | 6 |
| STX2 | STX2 | P32856 | Syntaxin-2 | chr12 | Not Cancer Driver | No | 1 | hippie | 43 | 140 | 25 | 25 | 0 |
| STX4 | STX4 | Q12846 | Syntaxin-4 | chr16 | Not Cancer Driver | No | 2 | hippie, biogrid | 50 | 152 | 20 | 20 | 0 |
| STXBP2_ENST00000221283 | STXBP2 | Q15833 | Syntaxin-binding protein 2 | chr19 | Not Cancer Driver | No | 1 | hippie | 77 | 80 | 13 | 13 | 5 |
| SYNE2_ENST00000344113 | SYNE2 | Q8WXH0 | Nesprin-2 | chr14 | Not Cancer Driver | No | 1 | hippie | 779 | 1888 | 220 | 220 | 1 |
| TAS2R19 | TAS2R19 | P59542 | Taste receptor type 2 member 19 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 0 | 0 | 0 | 0 |
| TMEM192 | TMEM192 | Q8IY95 | Transmembrane protein 192 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 5 | 1 | 1 | 0 |
| TMEM30B | TMEM30B | Q3MIR4 | Cell cycle control protein 50B | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 17 | 0 | 0 | 0 |
| TMEM97 | TMEM97 | Q5BJF2 | Sigma intracellular receptor 2 | chr17 | Not Cancer Driver | No | 3 | hippie, biogrid | 16 | 0 | 0 | 0 | 0 |
| TUBA3C | TUBA3C | P0DPH7 | Tubulin alpha-3C chain | chr13 | Not Cancer Driver | No | 2 | biogrid | 185 | 36 | 14 | 14 | 0 |
| TUBA3D | TUBA3D | P0DPH8 | Tubulin alpha-3D chain | chr2 | Not Cancer Driver | No | 1 | hippie | 74 | 36 | 4 | 4 | 0 |
| UBL4A | UBL4A | P11441 | Ubiquitin-like protein 4A | chrX | Not Cancer Driver | No | 1 | hippie | 22 | 16 | 5 | 5 | 0 |
| VAMP2_ENST00000316509 | VAMP2 | P63027 | Vesicle-associated membrane protein 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 7 | 47 | 4 | 4 | 3 |
| XPO1_ENST00000406957 | XPO1 | O14980 | Exportin-1 | chr2 | Census, Compendium | Yes | 1 | hippie | 140 | 33 | 9 | 9 | 0 |
| ZFPL1 | ZFPL1 | O95159 | Zinc finger protein-like 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 127 | 16 | 16 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|