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STX6 ,STX6 ,O43752
  • Number of Interaction partner in intact: 55
  • Number of Interaction partner in biogrid: 360
  • Number of Interaction partner in hippie: 427
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCA6 ABCA6 Q8N139 ATP-binding cassette sub-family A member 6 chr17 Not Cancer Driver No 1 hippie, biogrid 271 50 12 12 0
ACBD3 ACBD3 Q9H3P7 Golgi resident protein GCP60 chr1 Not Cancer Driver No 1 hippie, biogrid 59 350 40 40 0
ADCY9 ADCY9 O60503 Adenylate cyclase type 9 chr16 Not Cancer Driver No 1 hippie, biogrid 195 271 42 42 0
ADD3 ADD3 Q9UEY8 Gamma-adducin chr10 Not Cancer Driver No 1 hippie, biogrid 95 381 48 48 1
ADGRL2_ENST00000370728 ADGRL2 O95490 Adhesion G protein-coupled receptor L2 chr1 Not Cancer Driver No 1 hippie 373 452 122 122 0
AFTPH AFTPH Q6ULP2 Aftiphilin chr2 Not Cancer Driver No 1 hippie, biogrid 84 723 65 65 0
AGFG1_ENST00000310078 AGFG1 P52594 Arf-GAP domain and FG repeat-containing protein 1 chr2 Not Cancer Driver No 1 hippie, biogrid 60 395 50 50 0
AHCYL1 AHCYL1 O43865 S-adenosylhomocysteine hydrolase-like protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 58 108 10 10 0
AHNAK2 AHNAK2 Q8IVF2 Protein AHNAK2 chr14 Not Cancer Driver No 1 hippie, biogrid 1074 5470 1018 1018 0
AKAP12 AKAP12 Q02952 A-kinase anchor protein 12 chr6 Not Cancer Driver No 1 hippie, biogrid 215 1770 214 214 0
ALDH3A2_ENST00000579855 ALDH3A2 P51648 Aldehyde dehydrogenase family 3 member A2 chr17 Not Cancer Driver No 1 hippie, biogrid 47 5 2 2 26
ANK3 ANK3 Q12955 Ankyrin-3 chr10 Not Cancer Driver No 1 hippie, biogrid 860 3054 579 579 0
ANKFY1_ENST00000341657 ANKFY1 Q9P2R3 Rabankyrin-5 chr17 Not Cancer Driver No 1 hippie, biogrid 109 185 29 29 0
ANKLE2 ANKLE2 Q86XL3 Ankyrin repeat and LEM domain-containing protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 127 521 71 71 2
ANKRD26 ANKRD26 Q9UPS8 Ankyrin repeat domain-containing protein 26 chr10 Not Cancer Driver No 1 hippie, biogrid 224 1269 164 164 0
AP1AR AP1AR Q63HQ0 AP-1 complex-associated regulatory protein chr4 Not Cancer Driver No 1 hippie, biogrid 24 257 24 24 0
AP1B1 AP1B1 Q10567 AP-1 complex subunit beta-1 chr22 Not Cancer Driver No 1 hippie, biogrid 114 119 10 10 1
AP2A1 AP2A1 O95782 AP-2 complex subunit alpha-1 chr19 Not Cancer Driver No 1 hippie, biogrid 95 188 12 12 0
AP2A2_ENST00000448903 AP2A2 O94973 AP-2 complex subunit alpha-2 chr11 Not Cancer Driver No 1 hippie, biogrid 100 145 12 12 0
AP3D1_ENST00000345016 AP3D1 O14617 AP-3 complex subunit delta-1 chr19 Not Cancer Driver No 1 hippie, biogrid 138 404 59 59 0
AP4E1 AP4E1 Q9UPM8 AP-4 complex subunit epsilon-1 chr15 Not Cancer Driver No 1 hippie, biogrid 130 148 28 28 2
APBB1 APBB1 O00213 Amyloid beta precursor protein binding family B member 1 chr11 Not Cancer Driver No 1 hippie, biogrid 105 399 58 58 0
APBB2_ENST00000295974 APBB2 Q92870 Amyloid beta precursor protein binding family B member 2 chr4 Not Cancer Driver No 1 hippie, biogrid 88 419 51 51 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 intact, hippie 128 418 71 71 17
APPL1 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 Not Cancer Driver No 1 hippie, biogrid 67 292 31 31 1
AQP6_ENST00000315520 AQP6 Q13520 Aquaporin-6 chr12 Not Cancer Driver No 1 intact, hippie 48 22 4 4 0
ARFGAP2 ARFGAP2 Q8N6H7 ADP-ribosylation factor GTPase-activating protein 2 chr11 Not Cancer Driver No 1 hippie, biogrid 62 345 40 40 0
ARFGAP3 ARFGAP3 Q9NP61 ADP-ribosylation factor GTPase-activating protein 3 chr22 Not Cancer Driver No 1 hippie, biogrid 53 321 38 38 0
ARFGEF1 ARFGEF1 Q9Y6D6 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 chr8 Not Cancer Driver No 1 hippie, biogrid 243 456 54 54 0
ARFGEF2 ARFGEF2 Q9Y6D5 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 chr20 Not Cancer Driver No 1 hippie, biogrid 254 358 63 63 0
ARFIP2_ENST00000254584 ARFIP2 P53365 Arfaptin-2 chr11 Not Cancer Driver No 1 hippie, biogrid 37 144 15 15 0
ARHGAP1 ARHGAP1 Q07960 Rho GTPase-activating protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 39 90 8 8 0
ARHGAP21 ARHGAP21 Q5T5U3 Rho GTPase-activating protein 21 chr10 Not Cancer Driver No 1 hippie, biogrid 242 1612 204 204 0
ARHGEF10_ENST00000398564 ARHGEF10 O15013 Rho guanine nucleotide exchange factor 10 chr8 Census, Compendium Yes 1 hippie, biogrid 175 586 78 78 1
ARL13B ARL13B Q3SXY8 ADP-ribosylation factor-like protein 13B chr3 Not Cancer Driver No 1 hippie, biogrid 62 251 40 40 3
ARMC8_ENST00000469044 ARMC8 Q8IUR7 Armadillo repeat-containing protein 8 chr3 Not Cancer Driver No 1 intact, hippie 71 7 0 0 0
ASPH ASPH Q12797 Aspartyl/asparaginyl beta-hydroxylase chr8 Not Cancer Driver No 1 hippie, biogrid 109 373 53 53 1
ATP2B1_ENST00000261173 ATP2B1 P20020 Plasma membrane calcium-transporting ATPase 1 chr12 Not Cancer Driver No 1 hippie, biogrid 143 293 42 42 0
ATP6V1B2 ATP6V1B2 P21281 V-type proton ATPase subunit B, brain isoform chr8 Not Cancer Driver No 1 hippie, biogrid 63 49 4 4 1
B3GAT1_ENST00000312527 B3GAT1 Q9P2W7 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 chr11 Not Cancer Driver No 1 hippie, biogrid 85 93 32 32 0
B3GAT3 B3GAT3 O94766 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 42 139 17 17 2
BAIAP2 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 Not Cancer Driver No 1 hippie, biogrid 85 330 52 52 0
BASP1_ENST00000616743 BASP1 P80723 Brain acid soluble protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 39 227 39 39 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX Not Cancer Driver No 1 hippie, biogrid 37 104 14 14 0
BET1 BET1 O15155 BET1 homolog chr7 Not Cancer Driver No 2 hippie, biogrid 14 7 2 2 0
BMP2K BMP2K Q9NSY1 BMP-2-inducible protein kinase chr4 Not Cancer Driver No 1 hippie, biogrid 124 827 89 89 0
BNIP1_ENST00000351486 BNIP1 Q12981 Vesicle transport protein SEC20 chr5 Not Cancer Driver No 2 hippie, biogrid 43 57 10 10 0
BSG BSG P35613 Basigin chr19 Not Cancer Driver No 1 hippie, biogrid 43 123 17 17 0
C19orf18 C19orf18 Q8NEA5 Uncharacterized protein C19orf18 chr19 Not Cancer Driver No 1 hippie, biogrid 45 88 16 16 0
C1orf226_ENST00000458626 C1orf226 A1L170 Uncharacterized protein C1orf226 chr1 Not Cancer Driver No 1 hippie, biogrid 27 272 27 27 0
CAMLG CAMLG P49069 Guided entry of tail-anchored proteins factor CAMLG chr5 Not Cancer Driver No 1 hippie, biogrid 32 157 16 16 0
CARMIL1 CARMIL1 Q5VZK9 F-actin-uncapping protein LRRC16A chr6 Not Cancer Driver No 1 hippie 171 537 87 87 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie, biogrid 30 2 0 0 0
CBARP_ENST00000382477 CBARP Q8N350 Voltage-dependent calcium channel beta subunit-associated regulatory protein chr19 Not Cancer Driver No 1 hippie 41 661 33 33 0
CBR1 CBR1 P16152 Carbonyl reductase [NADPH] 1 chr21 Not Cancer Driver No 1 hippie, biogrid 27 62 11 11 0
CCDC47_ENST00000403162 CCDC47 Q96A33 PAT complex subunit CCDC47 chr17 Not Cancer Driver No 1 hippie, biogrid 49 265 23 23 0
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 Not Cancer Driver No 1 hippie, biogrid 226 1481 173 173 0
CDC42BPA_ENST00000334218 CDC42BPA Q5VT25 Serine/threonine-protein kinase MRCK alpha chr1 Not Cancer Driver No 1 hippie, biogrid 215 717 80 80 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CDCA3 CDCA3 Q99618 Cell division cycle-associated protein 3 chr12 Not Cancer Driver No 1 hippie, biogrid 26 268 26 26 0
CDKAL1 CDKAL1 Q5VV42 Threonylcarbamoyladenosine tRNA methylthiotransferase chr6 Not Cancer Driver No 1 hippie, biogrid 80 120 14 14 0
CEMIP2 CEMIP2 Q9UHN6 Cell surface hyaluronidase chr9 Not Cancer Driver No 1 hippie 198 229 26 26 0
CHST9_ENST00000581714 CHST9 Q7L1S5 Carbohydrate sulfotransferase 9 chr18 Not Cancer Driver No 1 hippie, biogrid 88 113 18 18 0
CKAP4 CKAP4 Q07065 Cytoskeleton-associated protein 4 chr12 Not Cancer Driver No 1 hippie, biogrid 73 409 55 55 0
CLCC1 CLCC1 Q96S66 Chloride channel CLIC-like protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 37 196 19 19 1
CLCN7 CLCN7 P51798 H(+)/Cl(-) exchange transporter 7 chr16 Not Cancer Driver No 1 hippie, biogrid 102 94 7 7 29
CLDND1_ENST00000510545 CLDND1 Q9NY35 Claudin domain-containing protein 1 chr3 Not Cancer Driver No 1 hippie, biogrid 32 0 0 0 0
CLEC12A_ENST00000304361 CLEC12A Q5QGZ9 C-type lectin domain family 12 member A chr12 Not Cancer Driver No 3 intact, hippie, biogrid 41 9 3 3 0
CLINT1_ENST00000411809 CLINT1 Q14677 Clathrin interactor 1 chr5 Not Cancer Driver No 1 hippie, biogrid 61 475 51 51 0
COG6 COG6 Q9Y2V7 Conserved oligomeric Golgi complex subunit 6 chr13 Not Cancer Driver No 2 intact, hippie, biogrid 83 141 16 16 1
COPB2 COPB2 P35606 Coatomer subunit beta' chr3 Not Cancer Driver No 1 hippie, biogrid 111 114 22 22 0
CPD CPD O75976 Carboxypeptidase D chr17 Not Cancer Driver No 1 hippie, biogrid 131 476 45 45 0
CPNE8 CPNE8 Q86YQ8 Copine-8 chr12 Not Cancer Driver No 1 hippie, biogrid 102 40 12 12 0
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 Not Cancer Driver No 1 intact 33 168 11 11 0
CRYBG3 CRYBG3 Q68DQ2 Very large A-kinase anchor protein chr3 Not Cancer Driver No 1 hippie, biogrid 179 1770 71 71 0
CSGALNACT1_ENST00000332246 CSGALNACT1 Q8TDX6 Chondroitin sulfate N-acetylgalactosaminyltransferase 1 chr8 Not Cancer Driver No 1 hippie, biogrid 91 131 28 28 0
CTNND1 CTNND1 O60716 Catenin delta-1 chr11 Census Yes 1 hippie, biogrid 154 570 83 83 0
CTXN1 CTXN1 P60606 Cortexin-1 chr19 Not Cancer Driver No 1 hippie, biogrid 1 19 0 0 0
CUX1_ENST00000622516 CUX1 Q13948 Protein CASP chr7 Census, Compendium Yes 4 intact, hippie, biogrid 114 347 64 64 0
CXADR CXADR P78310 Coxsackievirus and adenovirus receptor chr21 Not Cancer Driver No 1 hippie, biogrid 51 98 19 19 0
DAB2 DAB2 P98082 Disabled homolog 2 chr5 Not Cancer Driver No 1 hippie, biogrid 144 680 125 125 0
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie, biogrid 34 181 23 23 0
DENND4A_ENST00000431932 DENND4A Q7Z401 C-myc promoter-binding protein chr15 Not Cancer Driver No 1 hippie, biogrid 199 570 64 64 0
DENND4C_ENST00000602925 DENND4C Q5VZ89 DENN domain-containing protein 4C chr9 Not Cancer Driver No 1 hippie, biogrid 190 710 69 69 0
DIAPH3 DIAPH3 Q9NSV4 Protein diaphanous homolog 3 chr13 Not Cancer Driver No 1 hippie, biogrid 189 492 78 78 0
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 Not Cancer Driver No 1 hippie, biogrid 120 460 67 67 0
DLG5 DLG5 Q8TDM6 Disks large homolog 5 chr10 Not Cancer Driver No 1 hippie, biogrid 230 1119 135 135 0
DMXL1_ENST00000311085 DMXL1 Q9Y485 DmX-like protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 359 551 65 65 0
DNAJC5 DNAJC5 Q9H3Z4 DnaJ homolog subfamily C member 5 chr20 Not Cancer Driver No 1 intact, hippie 23 46 6 6 1
DSC2 DSC2 Q02487 Desmocollin-2 chr18 Not Cancer Driver No 1 hippie, biogrid 192 257 61 61 5
DSG2 DSG2 Q14126 Desmoglein-2 chr18 Not Cancer Driver No 1 hippie, biogrid 173 476 68 68 5
DST_ENST00000370788 DST Q03001-14 Isoform 9 of Dystonin chr6 Not Cancer Driver No 1 hippie, biogrid 729 1895 241 241 0
DTNA_ENST00000444659 DTNA Q9Y4J8 Dystrobrevin alpha chr18 Not Cancer Driver No 1 hippie, biogrid 162 412 86 86 0
EBP EBP Q15125 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase chrX Not Cancer Driver No 1 intact, hippie 30 9 0 0 9
EEA1 EEA1 Q15075 Early endosome antigen 1 chr12 Not Cancer Driver No 2 hippie, biogrid 151 1168 126 126 0
EFNB2_ENST00000245323 EFNB2 P52799 Ephrin-B2 chr13 Not Cancer Driver No 1 hippie, biogrid 42 97 15 15 0
EFR3B EFR3B Q9Y2G0 Protein EFR3 homolog B chr2 Not Cancer Driver No 1 hippie, biogrid 42 104 3 3 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EHBP1 EHBP1 Q8NDI1 EH domain-binding protein 1 chr2 Not Cancer Driver No 1 hippie, biogrid 148 914 115 115 0
EMD EMD P50402 Emerin chrX Not Cancer Driver No 1 hippie, biogrid 42 160 28 28 4
ENO1 ENO1 P06733 Alpha-enolase chr1 Not Cancer Driver No 1 hippie 51 21 2 2 0
EPB41L2_ENST00000368128 EPB41L2 O43491 Band 4.1-like protein 2 chr6 Not Cancer Driver No 1 hippie, biogrid 157 708 113 113 0
EPB41L5 EPB41L5 Q9HCM4 Band 4.1-like protein 5 chr2 Not Cancer Driver No 1 hippie, biogrid 97 312 45 45 0
EPB41_ENST00000373798 EPB41 P11171 Protein 4.1 chr1 Not Cancer Driver No 1 hippie, biogrid 101 557 69 69 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 Compendium Yes 1 hippie, biogrid 171 187 39 39 3
EPN2 EPN2 O95208 Epsin-2 chr17 Not Cancer Driver No 1 hippie, biogrid 73 543 61 61 0
EPS15L1_ENST00000248070 EPS15L1 Q9UBC2 Epidermal growth factor receptor substrate 15-like 1 chr19 Not Cancer Driver No 1 hippie, biogrid 109 603 76 76 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 1 hippie, biogrid 275 314 41 41 1
ERBIN_ENST00000284037 ERBIN Q96RT1 Erbin chr5 Not Cancer Driver No 1 hippie 167 967 118 118 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
ESYT1_ENST00000394048 ESYT1 Q9BSJ8 Extended synaptotagmin-1 chr12 Not Cancer Driver No 1 hippie, biogrid 126 278 32 32 0
ESYT2_ENST00000613624 ESYT2 A0FGR8 Extended synaptotagmin-2 chr7 Not Cancer Driver No 1 hippie, biogrid 94 376 25 25 0
EXOC3_ENST00000315013 EXOC3 O60645 Exocyst complex component 3 chr5 Not Cancer Driver No 1 hippie, biogrid 102 124 19 19 0
EXOC4 EXOC4 Q96A65 Exocyst complex component 4 chr7 Not Cancer Driver No 1 hippie, biogrid 164 133 33 33 0
FAM135A_ENST00000370479 FAM135A Q9P2D6 Protein FAM135A chr6 Not Cancer Driver No 1 hippie, biogrid 177 568 57 57 0
FAM171A2 FAM171A2 A8MVW0 Protein FAM171A2 chr17 Not Cancer Driver No 1 hippie, biogrid 13 478 4 4 0
FAM171B FAM171B Q6P995 Protein FAM171B chr2 Not Cancer Driver No 2 intact, hippie, biogrid 154 401 78 78 0
FAM210B FAM210B Q96KR6 Protein FAM210B, mitochondrial chr20 Not Cancer Driver No 1 intact, hippie 10 32 0 0 0
FAM234B FAM234B A2RU67 Protein FAM234B chr12 Not Cancer Driver No 1 hippie 91 136 26 26 0
FAM83B FAM83B Q5T0W9 Protein FAM83B chr6 Not Cancer Driver No 1 hippie, biogrid 314 684 219 219 0
FAM91A1 FAM91A1 Q658Y4 Protein FAM91A1 chr8 Not Cancer Driver No 1 hippie, biogrid 121 109 6 6 0
FAM9C_ENST00000380625 FAM9C Q8IZT9 Protein FAM9C chrX Not Cancer Driver No 1 hippie, biogrid 26 157 23 23 0
FCER1A FCER1A P12319 High affinity immunoglobulin epsilon receptor subunit alpha chr1 Not Cancer Driver No 1 hippie, biogrid 83 13 4 4 0
FLOT2 FLOT2 Q14254 Flotillin-2 chr17 Not Cancer Driver No 1 hippie, biogrid 56 20 3 3 0
FNDC3A_ENST00000492622 FNDC3A Q9Y2H6 Fibronectin type-III domain-containing protein 3A chr13 Not Cancer Driver No 1 hippie, biogrid 121 499 45 45 0
FRS2 FRS2 Q8WU20 Fibroblast growth factor receptor substrate 2 chr12 Not Cancer Driver No 1 hippie, biogrid 69 415 58 58 0
GAB1_ENST00000262994 GAB1 Q13480 GRB2-associated-binding protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 79 570 68 68 1
GAK GAK O14976 Cyclin-G-associated kinase chr4 Not Cancer Driver No 1 hippie, biogrid 146 589 79 79 0
GAL3ST2 GAL3ST2 Q9H3Q3 Galactose-3-O-sulfotransferase 2 chr2 Not Cancer Driver No 1 hippie, biogrid 36 13 0 0 0
GBF1 GBF1 Q92538 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 chr10 Not Cancer Driver No 1 hippie, biogrid 216 669 76 76 0
GCC1 GCC1 Q96CN9 GRIP and coiled-coil domain-containing protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 118 508 69 69 0
GCC2 GCC2 Q8IWJ2 GRIP and coiled-coil domain-containing protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 178 999 113 113 0
GGA3 GGA3 Q9NZ52 ADP-ribosylation factor-binding protein GGA3 chr17 Not Cancer Driver No 1 hippie, biogrid 73 419 41 41 0
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 Not Cancer Driver No 1 hippie, biogrid 86 110 26 26 50
GNAI3 GNAI3 P08754 Guanine nucleotide-binding protein G(i) subunit alpha-3 chr1 Not Cancer Driver No 1 hippie, biogrid 42 11 0 0 1
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 Not Cancer Driver No 1 hippie, biogrid 115 854 96 96 0
GOLGA3_ENST00000450791 GOLGA3 Q08378 Golgin subfamily A member 3 chr12 Not Cancer Driver No 1 hippie, biogrid 221 1272 189 189 0
GOLGA4_ENST00000361924 GOLGA4 Q13439 Golgin subfamily A member 4 chr3 Not Cancer Driver No 1 hippie, biogrid 231 1658 162 162 0
GOLGA5 GOLGA5 Q8TBA6 Golgin subfamily A member 5 chr14 Census Yes 1 hippie, biogrid 89 591 62 62 0
GOLGB1_ENST00000340645 GOLGB1 Q14789 Golgin subfamily B member 1 chr3 Not Cancer Driver No 1 hippie, biogrid 403 2416 300 300 0
GOPC GOPC Q9HD26 Golgi-associated PDZ and coiled-coil motif-containing protein chr6 Census Yes 2 hippie, biogrid 56 263 34 34 0
GORASP2 GORASP2 Q9H8Y8 Golgi reassembly-stacking protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 55 287 31 31 0
GOSR1 GOSR1 O95249 Golgi SNAP receptor complex member 1 chr17 Not Cancer Driver No 3 intact, hippie, biogrid 26 108 11 11 0
GOSR2_ENST00000640051 GOSR2 O14653 Golgi SNAP receptor complex member 2 chr17 Not Cancer Driver No 4 intact, hippie, biogrid 25 103 17 17 1
GPRC5B_ENST00000569479 GPRC5B Q9NZH0 G-protein coupled receptor family C group 5 member B chr16 Not Cancer Driver No 1 hippie, biogrid 82 75 19 19 0
GPRIN1 GPRIN1 Q7Z2K8 G protein-regulated inducer of neurite outgrowth 1 chr5 Not Cancer Driver No 1 hippie, biogrid 116 999 115 115 0
GRIPAP1 GRIPAP1 Q4V328 GRIP1-associated protein 1 chrX Not Cancer Driver No 1 hippie, biogrid 110 725 99 99 0
GTF3C1 GTF3C1 Q12789 General transcription factor 3C polypeptide 1 chr16 Not Cancer Driver No 3 intact, hippie, biogrid 323 735 114 114 0
GTF3C2 GTF3C2 Q8WUA4 General transcription factor 3C polypeptide 2 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 111 394 45 45 0
GTF3C3 GTF3C3 Q9Y5Q9 General transcription factor 3C polypeptide 3 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 109 195 22 22 0
HAUS1 HAUS1 Q96CS2 HAUS augmin-like complex subunit 1 chr18 Not Cancer Driver No 1 intact, hippie, biogrid 47 60 11 11 0
HEATR5A HEATR5A Q86XA9 HEAT repeat-containing protein 5A chr14 Not Cancer Driver No 1 hippie, biogrid 189 124 18 18 0
HGS HGS O14964 Hepatocyte growth factor-regulated tyrosine kinase substrate chr17 Not Cancer Driver No 1 hippie, biogrid 109 528 74 74 0
HIP1 HIP1 O00291 Huntingtin-interacting protein 1 chr7 Census, Compendium Yes 1 hippie, biogrid 137 510 70 70 0
HLA-A_ENST00000376809 HLA-A P04439 HLA class I histocompatibility antigen, A alpha chain chr6 Census, Compendium Yes 1 hippie, biogrid 128 125 60 60 0
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 intact, hippie 107 16 4 4 18
HTT HTT P42858 Huntingtin chr4 Not Cancer Driver No 1 hippie, biogrid 336 666 69 69 2
IFNAR1 IFNAR1 P17181 Interferon alpha/beta receptor 1 chr21 Compendium Yes 1 hippie, biogrid 55 50 6 6 0
IGF2R IGF2R P11717 Cation-independent mannose-6-phosphate receptor chr6 Not Cancer Driver No 1 hippie, biogrid 318 255 20 20 0
IL32 IL32 P24001 Interleukin-32 chr16 Not Cancer Driver No 1 hippie, biogrid 41 70 17 17 0
INF2 INF2 Q27J81 Inverted formin-2 chr14 Not Cancer Driver No 1 hippie, biogrid 120 635 49 49 30
IRS4 IRS4 O14654 Insulin receptor substrate 4 chrX Census, Compendium Yes 1 hippie, biogrid 297 798 203 203 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 Not Cancer Driver No 1 hippie, biogrid 103 84 10 10 0
ITSN1 ITSN1 Q15811 Intersectin-1 chr21 Not Cancer Driver No 1 hippie, biogrid 214 797 107 107 0
JPH1 JPH1 Q9HDC5 Junctophilin-1 chr8 Not Cancer Driver No 1 hippie, biogrid 131 421 89 89 0
JUP JUP P14923 Junction plakoglobin chr17 Not Cancer Driver No 1 hippie, biogrid 112 241 37 37 0
KCNE3 KCNE3 Q9Y6H6 Potassium voltage-gated channel subfamily E member 3 chr11 Not Cancer Driver No 1 hippie, biogrid 28 24 2 2 0
KIAA0319L KIAA0319L Q8IZA0 Dyslexia-associated protein KIAA0319-like protein chr1 Not Cancer Driver No 1 hippie, biogrid 117 508 58 58 0
KIDINS220 KIDINS220 Q9ULH0 Kinase D-interacting substrate of 220 kDa chr2 Not Cancer Driver No 1 hippie, biogrid 245 683 113 113 0
KIF13A KIF13A Q9H1H9 Kinesin-like protein KIF13A chr6 Not Cancer Driver No 1 hippie, biogrid 220 816 103 103 0
KIR2DL1 KIR2DL1 P43626 Killer cell immunoglobulin-like receptor 2DL1 chr19 Not Cancer Driver No 1 hippie, biogrid 112 135 44 44 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 intact, hippie, biogrid 788 7 2 2 27
KTN1 KTN1 Q86UP2 Kinectin chr14 Census Yes 1 hippie, biogrid 138 964 102 102 0
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 Not Cancer Driver No 1 hippie, biogrid 47 93 10 10 0
LAMP2_ENST00000200639 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX Not Cancer Driver No 1 hippie, biogrid 43 55 7 7 1
LAMP3 LAMP3 Q9UQV4 Lysosome-associated membrane glycoprotein 3 chr3 Not Cancer Driver No 1 hippie, biogrid 67 222 38 38 0
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 13 96 7 7 0
LEMD3 LEMD3 Q9Y2U8 Inner nuclear membrane protein Man1 chr12 Not Cancer Driver No 1 hippie, biogrid 78 509 33 33 0
LIME1 LIME1 Q9H400 Lck-interacting transmembrane adapter 1 chr20 Not Cancer Driver No 1 intact, hippie 22 193 17 17 0
LLGL1 LLGL1 Q15334 Lethal(2) giant larvae protein homolog 1 chr17 Not Cancer Driver No 1 hippie, biogrid 101 265 12 12 0
LMAN1 LMAN1 P49257 Protein ERGIC-53 chr18 Not Cancer Driver No 1 hippie, biogrid 63 222 25 25 1
LMNA LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie 68 544 49 49 131
LMTK2 LMTK2 Q8IWU2 Serine/threonine-protein kinase LMTK2 chr7 Not Cancer Driver No 1 hippie, biogrid 211 1018 141 141 0
LNPEP LNPEP Q9UIQ6 Leucyl-cystinyl aminopeptidase chr5 Not Cancer Driver No 1 hippie, biogrid 115 103 8 8 0
LRBA LRBA P50851 Lipopolysaccharide-responsive and beige-like anchor protein chr4 Not Cancer Driver No 1 hippie, biogrid 350 709 82 82 1
LRRC59 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie, biogrid 33 122 15 15 0
LSR_ENST00000361790 LSR Q86X29 Lipolysis-stimulated lipoprotein receptor chr19 Not Cancer Driver No 1 hippie, biogrid 89 330 42 42 0
LZTS2 LZTS2 Q9BRK4 Leucine zipper putative tumor suppressor 2 chr10 Not Cancer Driver No 1 hippie, biogrid 78 508 66 66 0
MACF1_ENST00000372915 MACF1 Q9UPN3 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 chr1 Not Cancer Driver No 1 hippie, biogrid 877 2826 334 334 4
MACO1 MACO1 Q8N5G2 Macoilin chr1 Not Cancer Driver No 1 hippie 79 407 52 52 0
MAP1LC3B MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 Not Cancer Driver No 1 hippie 10 17 1 1 0
MARCKS MARCKS P29966 Myristoylated alanine-rich C-kinase substrate chr6 Not Cancer Driver No 1 hippie, biogrid 14 328 14 14 0
MARK2 MARK2 Q7KZI7 Serine/threonine-protein kinase MARK2 chr11 Compendium Yes 1 hippie, biogrid 124 445 70 70 0
MARK3 MARK3 P27448 MAP/microtubule affinity-regulating kinase 3 chr14 Not Cancer Driver No 1 hippie, biogrid 92 376 49 49 1
MDFI MDFI Q99750 MyoD family inhibitor chr6 Not Cancer Driver No 1 hippie, biogrid 25 152 15 15 0
MEOX2 MEOX2 P50222 Homeobox protein MOX-2 chr7 Not Cancer Driver No 1 intact, hippie 70 274 63 63 0
MIA3 MIA3 Q5JRA6 Transport and Golgi organization protein 1 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 222 1490 178 178 0
MICALL1 MICALL1 Q8N3F8 MICAL-like protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 90 630 72 72 0
MMGT1 MMGT1 Q8N4V1 ER membrane protein complex subunit 5 chrX Not Cancer Driver No 1 intact, hippie 24 17 4 4 0
MON2 MON2 Q7Z3U7 Protein MON2 homolog chr12 Not Cancer Driver No 1 hippie, biogrid 201 151 16 16 0
MOSPD2 MOSPD2 Q8NHP6 Motile sperm domain-containing protein 2 chrX Not Cancer Driver No 1 intact, hippie 58 143 16 16 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MPP7 MPP7 Q5T2T1 MAGUK p55 subfamily member 7 chr10 Not Cancer Driver No 1 hippie, biogrid 132 199 72 72 0
MRAP2 MRAP2 Q96G30 Melanocortin-2 receptor accessory protein 2 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 55 75 17 17 0
MTERF2 MTERF2 Q49AM1 Transcription termination factor 2, mitochondrial chr12 Not Cancer Driver No 1 hippie 49 0 0 0 0
MTIF3_ENST00000381120 MTIF3 Q9H2K0 Translation initiation factor IF-3, mitochondrial chr13 Not Cancer Driver No 1 intact, hippie 26 180 19 19 0
MTMR6 MTMR6 Q9Y217 Myotubularin-related protein 6 chr13 Not Cancer Driver No 1 hippie, biogrid 87 68 16 16 0
MYO1B MYO1B O43795 Unconventional myosin-Ib chr2 Not Cancer Driver No 1 hippie, biogrid 144 34 4 4 0
MYO6 MYO6 Q9UM54 Unconventional myosin-VI chr6 Not Cancer Driver No 1 hippie, biogrid 176 342 41 41 3
NAPA NAPA P54920 Alpha-soluble NSF attachment protein chr19 Not Cancer Driver No 2 hippie, biogrid 33 11 0 0 0
NAPB_ENST00000377026 NAPB Q9H115 Beta-soluble NSF attachment protein chr20 Not Cancer Driver No 3 intact, hippie, biogrid 30 29 2 2 0
NAPG NAPG Q99747 Gamma-soluble NSF attachment protein chr18 Not Cancer Driver No 3 intact, hippie, biogrid 35 56 3 3 0
NBAS NBAS A2RRP1 NBAS subunit of NRZ tethering complex chr2 Not Cancer Driver No 3 intact, hippie, biogrid 365 246 41 41 5
NBEA NBEA Q8NFP9 Neurobeachin chr13 Census, Compendium Yes 1 hippie, biogrid 537 717 134 134 4
NCOA7_ENST00000368357 NCOA7 Q8NI08 Nuclear receptor coactivator 7 chr6 Not Cancer Driver No 1 hippie, biogrid 110 538 63 63 0
NDC1 NDC1 Q9BTX1 Nucleoporin NDC1 chr1 Not Cancer Driver No 1 hippie, biogrid 62 92 12 12 0
NDRG1 NDRG1 Q92597 Protein NDRG1 chr8 Census Yes 1 hippie, biogrid 66 140 22 22 0
NOS1AP NOS1AP O75052 Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein chr1 Not Cancer Driver No 1 hippie, biogrid 94 255 53 53 1
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 Census, Compendium Yes 1 hippie, biogrid 363 686 87 87 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 Census, Compendium Yes 1 hippie, biogrid 282 630 77 77 1
NRAS NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 284 10 0 0 14
NRSN1 NRSN1 Q8IZ57 Neurensin-1 chr6 Not Cancer Driver No 1 hippie, biogrid 46 17 9 9 0
NSF NSF P46459 Vesicle-fusing ATPase chr17 Not Cancer Driver No 3 hippie, biogrid 47 84 3 3 2
NUMBL NUMBL Q9Y6R0 Numb-like protein chr19 Not Cancer Driver No 1 hippie, biogrid 42 467 23 23 0
NUMB_ENST00000355058 NUMB P49757 Protein numb homolog chr14 Not Cancer Driver No 1 hippie, biogrid 70 490 58 58 0
NUP155 NUP155 O75694 Nuclear pore complex protein Nup155 chr5 Not Cancer Driver No 1 hippie, biogrid 154 221 19 19 1
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
OCLN OCLN Q16625 Occludin chr5 Not Cancer Driver No 1 biogrid 54 244 21 21 1
OCRL OCRL Q01968 Inositol polyphosphate 5-phosphatase OCRL chrX Not Cancer Driver No 1 hippie, biogrid 151 126 24 24 41
OSBPL11 OSBPL11 Q9BXB4 Oxysterol-binding protein-related protein 11 chr3 Not Cancer Driver No 1 hippie, biogrid 60 335 26 26 0
OSBPL8 OSBPL8 Q9BZF1 Oxysterol-binding protein-related protein 8 chr12 Not Cancer Driver No 1 hippie, biogrid 105 401 37 37 0
OTULINL OTULINL Q9NUU6 Inactive ubiquitin thioesterase OTULINL chr5 Not Cancer Driver No 1 hippie 59 21 0 0 0
PACSIN2_ENST00000402229 PACSIN2 Q9UNF0 Protein kinase C and casein kinase substrate in neurons protein 2 chr22 Not Cancer Driver No 1 hippie, biogrid 51 301 27 27 0
PAK4 PAK4 O96013 Serine/threonine-protein kinase PAK 4 chr19 Not Cancer Driver No 1 hippie, biogrid 58 340 33 33 0
PBXIP1 PBXIP1 Q96AQ6 Pre-B-cell leukemia transcription factor-interacting protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 100 605 86 86 0
PCDH7_ENST00000361762 PCDH7 O60245 Protocadherin-7 chr4 Not Cancer Driver No 1 hippie, biogrid 167 550 76 76 0
PDXDC1 PDXDC1 Q6P996 Pyridoxal-dependent decarboxylase domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie, biogrid 95 272 29 29 0
PDZD8 PDZD8 Q8NEN9 PDZ domain-containing protein 8 chr10 Not Cancer Driver No 1 hippie, biogrid 126 484 65 65 0
PEAK1_ENST00000312493 PEAK1 Q9H792 Inactive tyrosine-protein kinase PEAK1 chr15 Not Cancer Driver No 1 hippie, biogrid 222 1232 150 150 0
PHACTR4_ENST00000373839 PHACTR4 Q8IZ21 Phosphatase and actin regulator 4 chr1 Not Cancer Driver No 1 hippie, biogrid 80 679 76 76 0
PI4KB_ENST00000368873 PI4KB Q9UBF8 Phosphatidylinositol 4-kinase beta chr1 Not Cancer Driver No 1 hippie, biogrid 93 311 34 34 0
PICALM PICALM Q13492 Phosphatidylinositol-binding clathrin assembly protein chr11 Census Yes 1 hippie, biogrid 89 320 42 42 0
PIK3C2A PIK3C2A O00443 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha chr11 Not Cancer Driver No 1 hippie, biogrid 187 350 43 43 0
PKP4 PKP4 Q99569 Plakophilin-4 chr2 Not Cancer Driver No 1 hippie, biogrid 172 756 119 119 0
PLEKHA1 PLEKHA1 Q9HB21 Pleckstrin homology domain-containing family A member 1 chr10 Not Cancer Driver No 1 hippie, biogrid 61 191 32 32 0
PLEKHA5_ENST00000299275 PLEKHA5 Q9HAU0 Pleckstrin homology domain-containing family A member 5 chr12 Not Cancer Driver No 1 hippie, biogrid 144 869 114 114 0
PPFIA1 PPFIA1 Q13136 Liprin-alpha-1 chr11 Not Cancer Driver No 1 hippie, biogrid 164 865 126 126 0
PPFIBP1 PPFIBP1 Q86W92 Liprin-beta-1 chr12 Census Yes 1 hippie, biogrid 110 555 57 57 0
PPP1R37 PPP1R37 O75864 Protein phosphatase 1 regulatory subunit 37 chr19 Not Cancer Driver No 1 hippie, biogrid 8 343 7 7 0
PSMA3 PSMA3 P25788 Proteasome subunit alpha type-3 chr14 Not Cancer Driver No 1 intact, hippie 27 30 5 5 0
PTPN13_ENST00000411767 PTPN13 Q12923 Tyrosine-protein phosphatase non-receptor type 13 chr4 Census, Compendium Yes 1 hippie, biogrid 299 1231 149 149 0
PTPN23 PTPN23 Q9H3S7 Tyrosine-protein phosphatase non-receptor type 23 chr3 Not Cancer Driver No 1 hippie, biogrid 147 796 71 71 2
PTPN9 PTPN9 P43378 Tyrosine-protein phosphatase non-receptor type 9 chr15 Not Cancer Driver No 1 hippie 77 78 5 5 0
RAB11FIP1 RAB11FIP1 Q6WKZ4 Rab11 family-interacting protein 1 chr8 Not Cancer Driver No 1 hippie, biogrid 145 1118 133 133 0
RAB11FIP5 RAB11FIP5 Q9BXF6 Rab11 family-interacting protein 5 chr2 Not Cancer Driver No 2 hippie, biogrid 83 533 70 70 0
RAB4A RAB4A P20338 Ras-related protein Rab-4A chr1 Not Cancer Driver No 1 hippie, biogrid 26 32 11 11 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 hippie, biogrid 32 65 15 15 0
RAB5C_ENST00000393860 RAB5C P51148 Ras-related protein Rab-5C chr17 Not Cancer Driver No 1 hippie, biogrid 24 50 4 4 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 biogrid 27 11 0 0 4
RAB9A RAB9A P51151 Ras-related protein Rab-9A chrX Not Cancer Driver No 1 hippie, biogrid 18 21 1 1 0
RABEP1 RABEP1 Q15276 Rab GTPase-binding effector protein 1 chr17 Census, Compendium Yes 1 hippie, biogrid 81 520 57 57 0
RABGAP1 RABGAP1 Q9Y3P9 Rab GTPase-activating protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 114 407 40 40 0
RABL3 RABL3 Q5HYI8 Rab-like protein 3 chr3 Not Cancer Driver No 1 hippie, biogrid 37 1 0 0 1
RABL6_ENST00000311502 RABL6 Q3YEC7 Rab-like protein 6 chr9 Not Cancer Driver No 1 hippie, biogrid 71 529 48 48 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 66 2 1 1 6
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 Not Cancer Driver No 1 hippie 31 0 0 0 2
RAC3 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 Not Cancer Driver No 1 hippie 24 0 0 0 4
RAI14_ENST00000503673 RAI14 Q9P0K7 Ankycorbin chr5 Not Cancer Driver No 1 hippie, biogrid 117 693 78 78 0
RALGAPA1_ENST00000389698 RALGAPA1 Q6GYQ0 Ral GTPase-activating protein subunit alpha-1 chr14 Not Cancer Driver No 1 hippie, biogrid 227 649 73 73 1
RALGAPB_ENST00000397040 RALGAPB Q86X10 Ral GTPase-activating protein subunit beta chr20 Not Cancer Driver No 1 hippie, biogrid 202 376 54 54 0
RASAL2_ENST00000462775 RASAL2 Q9UJF2 Ras GTPase-activating protein nGAP chr1 Not Cancer Driver No 1 hippie, biogrid 164 606 86 86 0
RBX1 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 Not Cancer Driver No 1 hippie 10 18 1 1 0
RELCH RELCH Q9P260 RAB11-binding protein RELCH chr18 Not Cancer Driver No 1 hippie 114 384 29 29 0
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 1 hippie 52 19 2 2 0
RHOC_ENST00000369642 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 Not Cancer Driver No 1 hippie 30 53 7 7 0
RHOF RHOF Q9HBH0 Rho-related GTP-binding protein RhoF chr12 Not Cancer Driver No 1 hippie 18 10 0 0 0
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 26 22 5 5 0
RHOH_ENST00000617441 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 Census Yes 1 hippie 41 12 3 3 0
RHOJ RHOJ Q9H4E5 Rho-related GTP-binding protein RhoJ chr14 Not Cancer Driver No 1 hippie 39 0 0 0 0
RHOQ RHOQ P17081 Rho-related GTP-binding protein RhoQ chr2 Not Cancer Driver No 1 hippie 25 0 0 0 0
RHOU RHOU Q7L0Q8 Rho-related GTP-binding protein RhoU chr1 Not Cancer Driver No 1 hippie 34 63 6 6 0
RIC1 RIC1 Q4ADV7 Guanine nucleotide exchange factor subunit RIC1 chr9 Not Cancer Driver No 1 hippie, biogrid 159 252 15 15 1
RICTOR_ENST00000357387 RICTOR Q6R327 Rapamycin-insensitive companion of mTOR chr5 Not Cancer Driver No 1 hippie, biogrid 212 366 50 50 0
RINT1 RINT1 Q6NUQ1 RAD50-interacting protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 84 55 3 3 2
RND1 RND1 Q92730 Rho-related GTP-binding protein Rho6 chr12 Not Cancer Driver No 1 hippie 45 9 1 1 0
RND2 RND2 P52198 Rho-related GTP-binding protein RhoN chr17 Not Cancer Driver No 1 hippie 19 54 4 4 0
RNF149 RNF149 Q8NC42 E3 ubiquitin-protein ligase RNF149 chr2 Not Cancer Driver No 1 hippie, biogrid 41 102 10 10 0
ROBO1 ROBO1 Q9Y6N7 Roundabout homolog 1 chr3 Not Cancer Driver No 1 hippie, biogrid 353 1122 234 234 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 Not Cancer Driver No 1 hippie, biogrid 203 299 71 71 5
SCAMP1 SCAMP1 O15126 Secretory carrier-associated membrane protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 29 117 14 14 0
SCAMP2 SCAMP2 O15127 Secretory carrier-associated membrane protein 2 chr15 Not Cancer Driver No 1 hippie, biogrid 34 111 9 9 0
SCAMP5_ENST00000425597 SCAMP5 Q8TAC9 Secretory carrier-associated membrane protein 5 chr15 Not Cancer Driver No 1 intact, hippie 41 2 1 1 0
SCFD1 SCFD1 Q8WVM8 Sec1 family domain-containing protein 1 chr14 Not Cancer Driver No 3 hippie, biogrid 66 117 12 12 0
SCGN SCGN O76038 Secretagogin chr6 Not Cancer Driver No 1 hippie, biogrid 77 12 1 1 0
SCN3B_ENST00000299333 SCN3B Q9NY72 Sodium channel subunit beta-3 chr11 Not Cancer Driver No 1 intact, hippie 63 16 5 5 3
SCRIB_ENST00000320476 SCRIB Q14160 Protein scribble homolog chr8 Not Cancer Driver No 1 hippie, biogrid 196 1064 135 135 2
SCYL2_ENST00000360820 SCYL2 Q6P3W7 SCY1-like protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 103 328 29 29 0
SCYL3_ENST00000367770 SCYL3 Q8IZE3 Protein-associating with the carboxyl-terminal domain of ezrin chr1 Not Cancer Driver No 1 hippie, biogrid 81 249 28 28 0
SEC16A SEC16A O15027 Protein transport protein Sec16A chr9 Not Cancer Driver No 1 hippie, biogrid 285 1923 235 235 0
SEC24B_ENST00000265175 SEC24B O95487 Protein transport protein Sec24B chr4 Not Cancer Driver No 1 hippie, biogrid 135 526 55 55 0
SHB SHB Q15464 SH2 domain-containing adapter protein B chr9 Not Cancer Driver No 1 hippie, biogrid 56 334 36 36 0
SLC12A2 SLC12A2 P55011 Solute carrier family 12 member 2 chr5 Not Cancer Driver No 1 hippie, biogrid 141 297 18 18 8
SLC12A4_ENST00000316341 SLC12A4 Q9UP95 Solute carrier family 12 member 4 chr16 Not Cancer Driver No 1 hippie, biogrid 122 171 17 17 0
SLC12A6_ENST00000558667 SLC12A6 Q9UHW9 Solute carrier family 12 member 6 chr15 Not Cancer Driver No 1 hippie, biogrid 168 280 46 46 0
SLC12A7 SLC12A7 Q9Y666 Solute carrier family 12 member 7 chr5 Not Cancer Driver No 1 hippie, biogrid 153 202 23 23 0
SLC19A1 SLC19A1 P41440 Reduced folate transporter chr21 Not Cancer Driver No 1 hippie, biogrid 77 144 7 7 0
SLC29A1_ENST00000371708 SLC29A1 Q99808 Equilibrative nucleoside transporter 1 chr6 Not Cancer Driver No 1 hippie, biogrid 51 27 4 4 0
SLC30A1 SLC30A1 Q9Y6M5 Zinc transporter 1 chr1 Not Cancer Driver No 1 hippie, biogrid 49 144 9 9 0
SLC30A6_ENST00000282587 SLC30A6 Q6NXT4 Zinc transporter 6 chr2 Not Cancer Driver No 1 hippie, biogrid 54 93 7 7 0
SLC38A1_ENST00000546893 SLC38A1 Q9H2H9 Sodium-coupled neutral amino acid transporter 1 chr12 Not Cancer Driver No 1 hippie, biogrid 95 25 4 4 0
SLC38A2 SLC38A2 Q96QD8 Sodium-coupled neutral amino acid transporter 2 chr12 Not Cancer Driver No 1 hippie, biogrid 60 9 1 1 0
SLC39A10_ENST00000359634 SLC39A10 Q9ULF5 Zinc transporter ZIP10 chr2 Not Cancer Driver No 1 hippie, biogrid 111 417 63 63 0
SLC39A14_ENST00000381237 SLC39A14 Q15043 Metal cation symporter ZIP14 chr8 Not Cancer Driver No 1 hippie, biogrid 34 42 3 3 4
SLC39A4 SLC39A4 Q6P5W5 Zinc transporter ZIP4 chr8 Not Cancer Driver No 1 hippie, biogrid 77 116 11 11 9
SLC3A2_ENST00000377890 SLC3A2 P08195 4F2 cell-surface antigen heavy chain chr11 Not Cancer Driver No 1 hippie, biogrid 62 171 12 12 0
SLC4A7_ENST00000295736 SLC4A7 Q9Y6M7 Sodium bicarbonate cotransporter 3 chr3 Not Cancer Driver No 1 hippie, biogrid 165 406 57 57 0
SLC6A15 SLC6A15 Q9H2J7 Sodium-dependent neutral amino acid transporter B(0)AT2 chr12 Not Cancer Driver No 1 hippie, biogrid 163 70 22 22 0
SLC6A8 SLC6A8 P48029 Sodium- and chloride-dependent creatine transporter 1 chrX Not Cancer Driver No 1 hippie, biogrid 50 25 1 1 12
SLC7A2_ENST00000494857 SLC7A2 P52569 Cationic amino acid transporter 2 chr8 Not Cancer Driver No 1 hippie, biogrid 113 36 6 6 0
SLC7A5 SLC7A5 Q01650 Large neutral amino acids transporter small subunit 1 chr16 Not Cancer Driver No 1 hippie, biogrid 62 35 1 1 0
SMAP1 SMAP1 Q8IYB5 Stromal membrane-associated protein 1 chr6 Not Cancer Driver No 1 hippie, biogrid 54 352 46 46 0
SMAP2 SMAP2 Q8WU79 Stromal membrane-associated protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 50 214 30 30 0
SMCR8 SMCR8 Q8TEV9 Guanine nucleotide exchange protein SMCR8 chr17 Not Cancer Driver No 1 hippie, biogrid 107 357 38 38 0
SMPD4 SMPD4 Q9NXE4 Sphingomyelin phosphodiesterase 4 chr2 Not Cancer Driver No 1 hippie, biogrid 114 80 12 12 1
SNAP23 SNAP23 O00161 Synaptosomal-associated protein 23 chr15 Not Cancer Driver No 3 hippie, biogrid 18 179 16 16 0
SNAP29 SNAP29 O95721 Synaptosomal-associated protein 29 chr22 Not Cancer Driver No 3 hippie, biogrid 21 246 20 20 0
SNAP47_ENST00000366759 SNAP47 Q5SQN1 Synaptosomal-associated protein 47 chr1 Not Cancer Driver No 1 hippie, biogrid 51 192 20 20 0
SNX2 SNX2 O60749 Sorting nexin-2 chr5 Not Cancer Driver No 1 hippie, biogrid 45 218 18 18 0
SNX6 SNX6 Q9UNH7 Sorting nexin-6 chr14 Not Cancer Driver No 1 hippie, biogrid 33 85 7 7 0
SPRY4_ENST00000434127 SPRY4 Q9C004 Protein sprouty homolog 4 chr5 Not Cancer Driver No 1 hippie, biogrid 34 134 20 20 7
SPTAN1_ENST00000372731 SPTAN1 Q13813 Spectrin alpha chain, non-erythrocytic 1 chr9 Not Cancer Driver No 1 hippie, biogrid 315 980 114 114 0
SPTBN1 SPTBN1 Q01082 Spectrin beta chain, non-erythrocytic 1 chr2 Not Cancer Driver No 1 hippie, biogrid 311 869 123 123 0
SRPRA SRPRA P08240 Signal recognition particle receptor subunit alpha chr11 Not Cancer Driver No 1 hippie 95 232 40 40 0
STAM STAM Q92783 Signal transducing adapter molecule 1 chr10 Not Cancer Driver No 1 hippie, biogrid 73 361 40 40 0
STAM2 STAM2 O75886 Signal transducing adapter molecule 2 chr2 Not Cancer Driver No 1 hippie, biogrid 69 291 30 30 0
STEAP3_ENST00000393107 STEAP3 Q658P3 Metalloreductase STEAP3 chr2 Not Cancer Driver No 1 hippie, biogrid 82 30 2 2 0
STIM1_ENST00000300737 STIM1 Q13586 Stromal interaction molecule 1 chr11 Not Cancer Driver No 1 hippie, biogrid 70 387 45 45 13
STIM2_ENST00000467087 STIM2 Q9P246 Stromal interaction molecule 2 chr4 Not Cancer Driver No 1 hippie, biogrid 82 387 45 45 0
STOM STOM P27105 Stomatin chr9 Not Cancer Driver No 1 intact, hippie 23 44 3 3 0
STX10 STX10 O60499 Syntaxin-10 chr19 Not Cancer Driver No 3 hippie, biogrid 29 77 7 7 0
STX11 STX11 O75558 Syntaxin-11 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 71 48 7 7 0
STX12 STX12 Q86Y82 Syntaxin-12 chr1 Not Cancer Driver No 5 intact, hippie, biogrid 21 156 9 9 0
STX16 STX16 O14662 Syntaxin-16 chr20 Not Cancer Driver No 1 hippie 45 120 12 12 0
STX18 STX18 Q9P2W9 Syntaxin-18 chr4 Not Cancer Driver No 4 hippie, biogrid 28 174 15 15 0
STX1A STX1A Q16623 Syntaxin-1A chr7 Not Cancer Driver No 1 hippie 35 136 11 11 0
STX2 STX2 P32856 Syntaxin-2 chr12 Not Cancer Driver No 1 intact, hippie 43 140 25 25 0
STX3 STX3 Q13277 Syntaxin-3 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 51 129 30 30 0
STX4 STX4 Q12846 Syntaxin-4 chr16 Not Cancer Driver No 5 hippie, biogrid 50 152 20 20 0
STX5 STX5 Q13190 Syntaxin-5 chr11 Not Cancer Driver No 4 intact, hippie, biogrid 36 147 14 14 0
STX7 STX7 O15400 Syntaxin-7 chr6 Not Cancer Driver No 5 intact, hippie, biogrid 29 164 14 14 0
STX8 STX8 Q9UNK0 Syntaxin-8 chr17 Not Cancer Driver No 3 intact, hippie, biogrid 32 98 10 10 0
STXBP5 STXBP5 Q5T5C0 Syntaxin-binding protein 5 chr6 Not Cancer Driver No 3 intact, hippie, biogrid 128 344 46 46 0
STXBP6_ENST00000419632 STXBP6 Q8NFX7 Syntaxin-binding protein 6 chr14 Not Cancer Driver No 2 intact, hippie, biogrid 33 51 6 6 0
SYAP1 SYAP1 Q96A49 Synapse-associated protein 1 chrX Not Cancer Driver No 1 hippie, biogrid 31 221 22 22 0
SYNJ1 SYNJ1 O43426 Synaptojanin-1 chr21 Not Cancer Driver No 1 hippie, biogrid 208 584 76 76 3
TACC1 TACC1 O75410 Transforming acidic coiled-coil-containing protein 1 chr8 Not Cancer Driver No 1 hippie, biogrid 82 654 69 69 0
TBC1D10B TBC1D10B Q4KMP7 TBC1 domain family member 10B chr16 Not Cancer Driver No 1 hippie, biogrid 54 498 27 27 0
TBC1D22B TBC1D22B Q9NU19 TBC1 domain family member 22B chr6 Not Cancer Driver No 1 hippie, biogrid 55 205 27 27 0
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 Census Yes 3 hippie, biogrid 89 80 6 6 1
TGOLN2_ENST00000377386 TGOLN2 O43493 Trans-Golgi network integral membrane protein 2 chr2 Not Cancer Driver No 1 intact, hippie 51 399 46 46 0
TIMMDC1 TIMMDC1 Q9NPL8 Complex I assembly factor TIMMDC1, mitochondrial chr3 Not Cancer Driver No 1 hippie 44 50 6 6 0
TM4SF5 TM4SF5 O14894 Transmembrane 4 L6 family member 5 chr17 Not Cancer Driver No 1 hippie, biogrid 33 1 0 0 0
TMEM115 TMEM115 Q12893 Transmembrane protein 115 chr3 Not Cancer Driver No 1 hippie, biogrid 26 75 8 8 0
TMEM14B_ENST00000379542 TMEM14B Q9NUH8 Transmembrane protein 14B chr6 Not Cancer Driver No 1 intact, hippie 13 0 0 0 0
TMEM17 TMEM17 Q86X19 Transmembrane protein 17 chr2 Not Cancer Driver No 1 intact, hippie 22 14 2 2 0
TMEM171 TMEM171 Q8WVE6 Transmembrane protein 171 chr5 Not Cancer Driver No 1 hippie, biogrid 54 150 18 18 0
TMEM200A TMEM200A Q86VY9 Transmembrane protein 200A chr6 Not Cancer Driver No 2 intact, hippie, biogrid 194 272 116 116 0
TMEM205 TMEM205 Q6UW68 Transmembrane protein 205 chr19 Not Cancer Driver No 1 intact, hippie 20 19 4 4 0
TMEM216 TMEM216 Q9P0N5 Transmembrane protein 216 chr11 Not Cancer Driver No 1 intact, hippie 11 0 0 0 7
TMEM51_ENST00000376014 TMEM51 Q9NW97 Transmembrane protein 51 chr1 Not Cancer Driver No 1 hippie, biogrid 47 181 37 37 0
TMEM74 TMEM74 Q96NL1 Transmembrane protein 74 chr8 Not Cancer Driver No 1 hippie, biogrid 93 127 42 42 0
TMEM86B TMEM86B Q8N661 Lysoplasmalogenase chr19 Not Cancer Driver No 1 hippie 15 1 0 0 0
TMEM87A TMEM87A Q8NBN3 Transmembrane protein 87A chr15 Not Cancer Driver No 1 hippie, biogrid 60 71 10 10 0
TMEM98 TMEM98 Q9Y2Y6 Transmembrane protein 98 chr17 Not Cancer Driver No 1 hippie, biogrid 39 27 3 3 2
TMEM9B TMEM9B Q9NQ34 Transmembrane protein 9B chr11 Not Cancer Driver No 1 hippie, biogrid 12 0 0 0 0
TMEM9_ENST00000485839 TMEM9 Q9P0T7 Proton-transporting V-type ATPase complex assembly regulator TMEM9 chr1 Not Cancer Driver No 2 hippie, biogrid 22 23 3 3 0
TMF1 TMF1 P82094 TATA element modulatory factor chr3 Not Cancer Driver No 1 hippie, biogrid 109 946 99 99 0
TOR1AIP1_ENST00000606911 TOR1AIP1 Q5JTV8 Torsin-1A-interacting protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 71 401 44 44 0
TPCN2 TPCN2 Q8NHX9 Two pore channel protein 2 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 73 16 0 0 0
TRAPPC10 TRAPPC10 P48553 Trafficking protein particle complex subunit 10 chr21 Not Cancer Driver No 1 hippie, biogrid 139 174 14 14 0
TRAPPC8 TRAPPC8 Q9Y2L5 Trafficking protein particle complex subunit 8 chr18 Not Cancer Driver No 1 hippie, biogrid 161 258 46 46 0
TRAPPC9_ENST00000438773 TRAPPC9 Q96Q05 Trafficking protein particle complex subunit 9 chr8 Not Cancer Driver No 1 hippie, biogrid 155 132 21 21 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIP11 TRIP11 Q15643 Thyroid receptor-interacting protein 11 chr14 Census, Compendium Yes 1 hippie, biogrid 218 1364 161 161 2
TSC1 TSC1 Q92574 Hamartin chr9 Census, Compendium Yes 1 hippie, biogrid 135 732 78 78 11
TSPAN3 TSPAN3 O60637 Tetraspanin-3 chr15 Not Cancer Driver No 3 hippie, biogrid 23 0 0 0 0
UBIAD1 UBIAD1 Q9Y5Z9 UbiA prenyltransferase domain-containing protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 46 18 1 1 19
UBXN4 UBXN4 Q92575 UBX domain-containing protein 4 chr2 Not Cancer Driver No 1 hippie, biogrid 69 302 41 41 0
UGT8 UGT8 Q16880 2-hydroxyacylsphingosine 1-beta-galactosyltransferase chr4 Not Cancer Driver No 1 hippie, biogrid 107 18 2 2 0
UHRF1BP1 UHRF1BP1 Q6BDS2 UHRF1-binding protein 1 chr6 Not Cancer Driver No 1 hippie, biogrid 165 578 61 61 0
UHRF1BP1L UHRF1BP1L A0JNW5 UHRF1-binding protein 1-like chr12 Not Cancer Driver No 1 hippie, biogrid 195 569 69 69 0
UNC5B UNC5B Q8IZJ1 Netrin receptor UNC5B chr10 Not Cancer Driver No 1 hippie, biogrid 155 117 20 20 0
UNC5C UNC5C O95185 Netrin receptor UNC5C chr4 Not Cancer Driver No 1 hippie, biogrid 189 86 18 18 1
USO1_ENST00000514213 USO1 O60763 General vesicular transport factor p115 chr4 Not Cancer Driver No 1 hippie, biogrid 78 368 28 28 0
USP8 USP8 P40818 Ubiquitin carboxyl-terminal hydrolase 8 chr15 Census, Compendium Yes 1 hippie, biogrid 122 602 69 69 0
UTRN UTRN P46939 Utrophin chr6 Not Cancer Driver No 1 hippie, biogrid 476 1283 183 183 0
VAMP2_ENST00000316509 VAMP2 P63027 Vesicle-associated membrane protein 2 chr17 Not Cancer Driver No 2 hippie, biogrid 7 47 4 4 3
VAMP3 VAMP3 Q15836 Vesicle-associated membrane protein 3 chr1 Not Cancer Driver No 5 hippie, biogrid 11 17 1 1 0
VAMP4 VAMP4 O75379 Vesicle-associated membrane protein 4 chr1 Not Cancer Driver No 6 intact, hippie, biogrid 9 80 6 6 0
VAMP5 VAMP5 O95183 Vesicle-associated membrane protein 5 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 17 19 1 1 0
VAMP7_ENST00000286448 VAMP7 P51809 Vesicle-associated membrane protein 7 chrX Not Cancer Driver No 2 hippie, biogrid 38 4 1 1 0
VAMP8 VAMP8 Q9BV40 Vesicle-associated membrane protein 8 chr2 Not Cancer Driver No 4 hippie, biogrid 9 27 0 0 0
VANGL1 VANGL1 Q8TAA9 Vang-like protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 72 140 15 15 3
VANGL2 VANGL2 Q9ULK5 Vang-like protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 122 150 37 37 3
VEZT VEZT Q9HBM0 Vezatin chr12 Not Cancer Driver No 1 hippie, biogrid 83 278 22 22 0
VIPAS39 VIPAS39 Q9H9C1 Spermatogenesis-defective protein 39 homolog chr14 Not Cancer Driver No 1 hippie, biogrid 63 126 14 14 0
VPS11 VPS11 Q9H270 Vacuolar protein sorting-associated protein 11 homolog chr11 Not Cancer Driver No 1 hippie 96 118 6 6 1
VPS13B VPS13B Q7Z7G8 Intermembrane lipid transfer protein VPS13B chr8 Not Cancer Driver No 1 hippie, biogrid 660 635 106 106 5
VPS18 VPS18 Q9P253 Vacuolar protein sorting-associated protein 18 homolog chr15 Not Cancer Driver No 1 hippie 96 86 7 7 0
VPS33B VPS33B Q9H267 Vacuolar protein sorting-associated protein 33B chr15 Not Cancer Driver No 1 hippie, biogrid 54 17 0 0 2
VPS45_ENST00000644510 VPS45 Q9NRW7 Vacuolar protein sorting-associated protein 45 chr1 Not Cancer Driver No 3 hippie, biogrid 66 57 5 5 2
VPS50 VPS50 Q96JG6 Syndetin chr7 Not Cancer Driver No 1 intact, hippie 175 171 32 32 0
VPS51 VPS51 Q9UID3 Vacuolar protein sorting-associated protein 51 homolog chr11 Not Cancer Driver No 3 intact, hippie, biogrid 75 150 11 11 1
VPS52 VPS52 Q8N1B4 Vacuolar protein sorting-associated protein 52 homolog chr6 Not Cancer Driver No 1 hippie 89 36 5 5 0
VPS53 VPS53 Q5VIR6 Vacuolar protein sorting-associated protein 53 homolog chr17 Not Cancer Driver No 2 hippie, biogrid 83 172 27 27 1
VPS54 VPS54 Q9P1Q0 Vacuolar protein sorting-associated protein 54 chr2 Not Cancer Driver No 2 hippie, biogrid 93 152 14 14 0
VTI1A VTI1A Q96AJ9 Vesicle transport through interaction with t-SNAREs homolog 1A chr10 Census Yes 5 intact, hippie, biogrid 21 138 13 13 0
VTI1B VTI1B Q9UEU0 Vesicle transport through interaction with t-SNAREs homolog 1B chr14 Not Cancer Driver No 4 hippie, biogrid 25 192 20 20 0
WASHC2A WASHC2A Q641Q2 WASH complex subunit 2A chr10 Not Cancer Driver No 1 hippie 48 1222 42 42 0
WASHC2C_ENST00000374362 WASHC2C Q9Y4E1 WASH complex subunit 2C chr10 Not Cancer Driver No 1 hippie 90 1204 89 89 0
WDR7 WDR7 Q9Y4E6 WD repeat-containing protein 7 chr18 Not Cancer Driver No 1 hippie, biogrid 199 292 37 37 0
XPR1 XPR1 Q9UBH6 Xenotropic and polytropic retrovirus receptor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 103 70 15 15 4
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 Not Cancer Driver No 1 hippie, biogrid 65 62 10 10 0
YKT6 YKT6 O15498 Synaptobrevin homolog YKT6 chr7 Not Cancer Driver No 2 hippie, biogrid 19 21 2 2 0
ZC3HAV1 ZC3HAV1 Q7Z2W4 Zinc finger CCCH-type antiviral protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 142 344 63 63 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie, biogrid 89 462 63 63 0
ZFYVE16 ZFYVE16 Q7Z3T8 Zinc finger FYVE domain-containing protein 16 chr5 Not Cancer Driver No 1 hippie, biogrid 155 651 65 65 0
ZFYVE9 ZFYVE9 O95405 Zinc finger FYVE domain-containing protein 9 chr1 Not Cancer Driver No 1 hippie, biogrid 162 668 83 83 0