Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCA1 | ABCA1 | O95477 | Phospholipid-transporting ATPase ABCA1 | chr9 | Not Cancer Driver | No | 1 | hippie | 284 | 245 | 40 | 40 | 31 |
| AC004754.1 | FAM234A | B4DGG1 | Protein FAM234A | chr16 | Not Cancer Driver | No | 2 | intact, hippie | 56 | 69 | 9 | 9 | 0 |
| ACE2 | ACE2 | Q9BYF1 | Angiotensin-converting enzyme 2 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 104 | 68 | 5 | 5 | 0 |
| ACP2 | ACP2 | P11117 | Lysosomal acid phosphatase | chr11 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 41 | 77 | 11 | 11 | 0 |
| ADPGK | ADPGK | Q9BRR6 | ADP-dependent glucokinase | chr15 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 38 | 24 | 0 | 0 | 0 |
| ANKFY1_ENST00000341657 | ANKFY1 | Q9P2R3 | Rabankyrin-5 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 109 | 185 | 29 | 29 | 0 |
| ANXA11 | ANXA11 | P50995 | Annexin A11 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 244 | 31 | 31 | 1 |
| AQP6_ENST00000315520 | AQP6 | Q13520 | Aquaporin-6 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 48 | 22 | 4 | 4 | 0 |
| AQP8 | AQP8 | O94778 | Aquaporin-8 | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 49 | 0 | 0 | 0 | 0 |
| ARF6 | ARF6 | P62330 | ADP-ribosylation factor 6 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 5 | 0 | 0 | 0 |
| ASPH | ASPH | Q12797 | Aspartyl/asparaginyl beta-hydroxylase | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 109 | 373 | 53 | 53 | 1 |
| ATP4A | ATP4A | P20648 | Potassium-transporting ATPase alpha chain 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 201 | 121 | 30 | 30 | 0 |
| ATP5MG | ATP5MG | O75964 | ATP synthase subunit g, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie | 16 | 0 | 0 | 0 | 0 |
| ATP6V1B1 | ATP6V1B1 | P15313 | V-type proton ATPase subunit B, kidney isoform | chr2 | Not Cancer Driver | No | 1 | hippie | 77 | 66 | 14 | 14 | 9 |
| B3GAT1_ENST00000312527 | B3GAT1 | Q9P2W7 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 85 | 93 | 32 | 32 | 0 |
| BCL2L13_ENST00000317582 | BCL2L13 | Q9BXK5 | Bcl-2-like protein 13 | chr22 | Not Cancer Driver | No | 1 | hippie | 49 | 291 | 30 | 30 | 0 |
| BET1 | BET1 | O15155 | BET1 homolog | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 7 | 2 | 2 | 0 |
| BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | Census, Compendium | Yes | 1 | hippie | 77 | 98 | 16 | 16 | 0 |
| BLOC1S6_ENST00000220531 | BLOC1S6 | Q9UL45 | Biogenesis of lysosome-related organelles complex 1 subunit 6 | chr15 | Not Cancer Driver | No | 2 | hippie, biogrid | 12 | 111 | 11 | 11 | 0 |
| BNIP1_ENST00000351486 | BNIP1 | Q12981 | Vesicle transport protein SEC20 | chr5 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 43 | 57 | 10 | 10 | 0 |
| BZW2_ENST00000258761 | BZW2 | Q9Y6E2 | eIF5-mimic protein 1 | chr7 | Not Cancer Driver | No | 3 | hippie, biogrid | 41 | 58 | 8 | 8 | 0 |
| CAV1 | CAV1 | Q03135 | Caveolin-1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 2 | 0 | 0 | 0 |
| CCDC138 | CCDC138 | Q96M89 | Coiled-coil domain-containing protein 138 | chr2 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 76 | 202 | 25 | 25 | 0 |
| CCDC155 | KASH5 | Q8N6L0 | Protein KASH5 | chr19 | Not Cancer Driver | No | 1 | intact | 88 | 401 | 70 | 70 | 0 |
| CCR1 | CCR1 | P32246 | C-C chemokine receptor type 1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 69 | 14 | 5 | 5 | 0 |
| CD79A | CD79A | P11912 | B-cell antigen receptor complex-associated protein alpha chain | chr19 | Census | Yes | 1 | intact, hippie | 32 | 28 | 3 | 3 | 0 |
| CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 39 | 23 | 2 | 2 | 1 |
| CISD1 | CISD1 | Q9NZ45 | CDGSH iron-sulfur domain-containing protein 1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 6 | 18 | 0 | 0 | 0 |
| CISD2 | CISD2 | Q8N5K1 | CDGSH iron-sulfur domain-containing protein 2 | chr4 | Not Cancer Driver | No | 1 | hippie | 11 | 7 | 0 | 0 | 0 |
| COG6 | COG6 | Q9Y2V7 | Conserved oligomeric Golgi complex subunit 6 | chr13 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 83 | 141 | 16 | 16 | 1 |
| DDX58 | DDX58 | O95786 | Antiviral innate immune response receptor RIG-I | chr9 | Not Cancer Driver | No | 1 | hippie | 118 | 61 | 10 | 10 | 2 |
| DNAJC5 | DNAJC5 | Q9H3Z4 | DnaJ homolog subfamily C member 5 | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 23 | 46 | 6 | 6 | 1 |
| DPP4 | DPP4 | P27487 | Dipeptidyl peptidase 4 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 151 | 8 | 1 | 1 | 0 |
| DTX2 | DTX2 | Q86UW9 | Probable E3 ubiquitin-protein ligase DTX2 | chr7 | Not Cancer Driver | No | 1 | hippie | 84 | 292 | 42 | 42 | 0 |
| EBP | EBP | Q15125 | 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase | chrX | Not Cancer Driver | No | 1 | intact, hippie | 30 | 9 | 0 | 0 | 9 |
| EEA1 | EEA1 | Q15075 | Early endosome antigen 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 151 | 1168 | 126 | 126 | 0 |
| EHD1_ENST00000359393 | EHD1 | Q9H4M9 | EH domain-containing protein 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 72 | 90 | 12 | 12 | 0 |
| EIF2B1 | EIF2B1 | Q14232 | Translation initiation factor eIF-2B subunit alpha | chr12 | Not Cancer Driver | No | 3 | hippie, biogrid | 33 | 0 | 0 | 0 | 2 |
| EIF2B2 | EIF2B2 | P49770 | Translation initiation factor eIF-2B subunit beta | chr14 | Not Cancer Driver | No | 3 | hippie, biogrid | 40 | 83 | 11 | 11 | 9 |
| EIF2B3 | EIF2B3 | Q9NR50 | Translation initiation factor eIF-2B subunit gamma | chr1 | Not Cancer Driver | No | 3 | hippie, biogrid | 54 | 28 | 9 | 9 | 5 |
| EIF2B4_ENST00000347454 | EIF2B4 | Q9UI10 | Translation initiation factor eIF-2B subunit delta | chr2 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 57 | 212 | 29 | 29 | 7 |
| EIF2B5 | EIF2B5 | Q13144 | Translation initiation factor eIF-2B subunit epsilon | chr3 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 76 | 179 | 16 | 16 | 29 |
| ELAVL1 | ELAVL1 | Q15717 | ELAV-like protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 69 | 43 | 5 | 5 | 0 |
| EPB42_ENST00000441366 | EPB42 | P16452 | Protein 4.2 | chr15 | Not Cancer Driver | No | 1 | hippie | 94 | 113 | 10 | 10 | 4 |
| ERGIC3_ENST00000348547 | ERGIC3 | Q9Y282 | Endoplasmic reticulum-Golgi intermediate compartment protein 3 | chr20 | Not Cancer Driver | No | 1 | hippie | 53 | 23 | 3 | 3 | 0 |
| EWSR1_ENST00000397938 | EWSR1 | Q01844 | RNA-binding protein EWS | chr22 | Census, Compendium | Yes | 1 | hippie | 94 | 646 | 93 | 93 | 0 |
| F3 | F3 | P13726 | Tissue factor | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 61 | 7 | 7 | 0 |
| FAM160A2_ENST00000449352 | FHIP1B | Q8N612 | FHF complex subunit HOOK interacting protein 1B | chr11 | Not Cancer Driver | No | 1 | intact | 129 | 415 | 54 | 54 | 0 |
| FAM160B1 | FHIP2A | Q5W0V3 | FHF complex subunit HOOK interacting protein 2A | chr10 | Not Cancer Driver | No | 1 | intact | 92 | 130 | 13 | 13 | 0 |
| FAM234A_ENST00000301678 | FAM234A | Q9H0X4 | Protein FAM234A | chr16 | Not Cancer Driver | No | 2 | intact, hippie | 60 | 99 | 11 | 11 | 0 |
| FAM234B | FAM234B | A2RU67 | Protein FAM234B | chr12 | Not Cancer Driver | No | 1 | hippie | 91 | 136 | 26 | 26 | 0 |
| FCER1G | FCER1G | P30273 | High affinity immunoglobulin epsilon receptor subunit gamma | chr1 | Not Cancer Driver | No | 1 | hippie | 10 | 13 | 2 | 2 | 0 |
| FGFR1_ENST00000447712 | FGFR1 | P11362 | Fibroblast growth factor receptor 1 | chr8 | Census, Compendium | Yes | 1 | hippie | 152 | 230 | 43 | 43 | 74 |
| FRMD5 | FRMD5 | Q7Z6J6 | FERM domain-containing protein 5 | chr15 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 69 | 134 | 20 | 20 | 0 |
| GATA3_ENST00000346208 | GATA3 | P23771 | Trans-acting T-cell-specific transcription factor GATA-3 | chr10 | Census, Compendium | Yes | 1 | intact | 111 | 364 | 87 | 87 | 2 |
| GJA1 | GJA1 | P17302 | Gap junction alpha-1 protein | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 86 | 110 | 26 | 26 | 50 |
| GJA8 | GJA8 | P48165 | Gap junction alpha-8 protein | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 139 | 173 | 56 | 56 | 9 |
| GOLGA2_ENST00000611957 | GOLGA2 | Q08379 | Golgin subfamily A member 2 | chr9 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 115 | 854 | 96 | 96 | 0 |
| GORASP1 | GORASP1 | Q9BQQ3 | Golgi reassembly-stacking protein 1 | chr3 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 49 | 293 | 32 | 32 | 0 |
| GOSR1 | GOSR1 | O95249 | Golgi SNAP receptor complex member 1 | chr17 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 26 | 108 | 11 | 11 | 0 |
| GOSR2_ENST00000640051 | GOSR2 | O14653 | Golgi SNAP receptor complex member 2 | chr17 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 25 | 103 | 17 | 17 | 1 |
| HGS | HGS | O14964 | Hepatocyte growth factor-regulated tyrosine kinase substrate | chr17 | Not Cancer Driver | No | 1 | hippie | 109 | 528 | 74 | 74 | 0 |
| HOMER1 | HOMER1 | Q86YM7 | Homer protein homolog 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 46 | 243 | 32 | 32 | 0 |
| HRAS | HRAS | P01112 | GTPase HRas | chr11 | Census, Compendium | Yes | 1 | intact, hippie | 107 | 16 | 4 | 4 | 18 |
| HSCB | HSCB | Q8IWL3 | Iron-sulfur cluster co-chaperone protein HscB | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 36 | 25 | 6 | 6 | 0 |
| IFITM1_ENST00000528780 | IFITM1 | P13164 | Interferon-induced transmembrane protein 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 0 | 0 | 0 | 0 |
| IFITM3 | IFITM3 | Q01628 | Interferon-induced transmembrane protein 3 | chr11 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 69 | 18 | 5 | 5 | 0 |
| IL32 | IL32 | P24001 | Interleukin-32 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 70 | 17 | 17 | 0 |
| ITFG1 | ITFG1 | Q8TB96 | T-cell immunomodulatory protein | chr16 | Not Cancer Driver | No | 1 | hippie | 70 | 18 | 3 | 3 | 0 |
| KCNE3 | KCNE3 | Q9Y6H6 | Potassium voltage-gated channel subfamily E member 3 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 24 | 2 | 2 | 0 |
| KDSR | KDSR | Q06136 | 3-ketodihydrosphingosine reductase | chr18 | Census | Yes | 1 | hippie, biogrid | 31 | 35 | 4 | 4 | 1 |
| KRAS | KRAS | P01116 | GTPase KRas | chr12 | Census, Compendium | Yes | 2 | intact, hippie, biogrid | 788 | 7 | 2 | 2 | 27 |
| LAMP1 | LAMP1 | P11279 | Lysosome-associated membrane glycoprotein 1 | chr13 | Not Cancer Driver | No | 2 | hippie, biogrid | 47 | 93 | 10 | 10 | 0 |
| LAMP2_ENST00000200639 | LAMP2 | P13473 | Lysosome-associated membrane glycoprotein 2 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 55 | 7 | 7 | 1 |
| LAMP3 | LAMP3 | Q9UQV4 | Lysosome-associated membrane glycoprotein 3 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 222 | 38 | 38 | 0 |
| LAMTOR1 | LAMTOR1 | Q6IAA8 | Ragulator complex protein LAMTOR1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 13 | 96 | 7 | 7 | 0 |
| LEPROTL1_ENST00000321250 | LEPROTL1 | O95214 | Leptin receptor overlapping transcript-like 1 | chr8 | Census | Yes | 1 | hippie | 8 | 0 | 0 | 0 | 0 |
| LGALS9 | LGALS9 | O00182 | Galectin-9 | chr17 | Not Cancer Driver | No | 1 | hippie | 54 | 65 | 16 | 16 | 0 |
| LMBR1L | LMBR1L | Q6UX01 | Protein LMBR1L | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 4 | 0 | 0 | 0 |
| LMNA | LMNA | P02545 | Prelamin-A/C | chr1 | Census | Yes | 1 | hippie | 68 | 544 | 49 | 49 | 131 |
| LRRC4 | LRRC4 | Q9HBW1 | Leucine-rich repeat-containing protein 4 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 117 | 110 | 14 | 14 | 0 |
| MAP1B | MAP1B | P46821 | Microtubule-associated protein 1B | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 332 | 1947 | 278 | 278 | 0 |
| MAP1LC3B | MAP1LC3B | Q9GZQ8 | Microtubule-associated proteins 1A/1B light chain 3B | chr16 | Not Cancer Driver | No | 1 | hippie | 10 | 17 | 1 | 1 | 0 |
| MARCKS | MARCKS | P29966 | Myristoylated alanine-rich C-kinase substrate | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 328 | 14 | 14 | 0 |
| MFSD6_ENST00000281416 | MFSD6 | Q6ZSS7 | Major facilitator superfamily domain-containing protein 6 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 82 | 252 | 26 | 26 | 0 |
| MMGT1 | MMGT1 | Q8N4V1 | ER membrane protein complex subunit 5 | chrX | Not Cancer Driver | No | 1 | intact, hippie | 24 | 17 | 4 | 4 | 0 |
| MOSPD2 | MOSPD2 | Q8NHP6 | Motile sperm domain-containing protein 2 | chrX | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 58 | 143 | 16 | 16 | 0 |
| MOV10_ENST00000357443 | MOV10 | Q9HCE1 | Helicase MOV-10 | chr1 | Not Cancer Driver | No | 1 | hippie | 110 | 101 | 8 | 8 | 0 |
| MYEF2 | MYEF2 | Q9P2K5 | Myelin expression factor 2 | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 85 | 370 | 45 | 45 | 0 |
| MYH9 | MYH9 | P35579 | Myosin-9 | chr22 | Census, Compendium | Yes | 1 | intact, hippie | 310 | 1120 | 160 | 160 | 17 |
| NAPA | NAPA | P54920 | Alpha-soluble NSF attachment protein | chr19 | Not Cancer Driver | No | 4 | hippie, biogrid | 33 | 11 | 0 | 0 | 0 |
| NAPB_ENST00000377026 | NAPB | Q9H115 | Beta-soluble NSF attachment protein | chr20 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 30 | 29 | 2 | 2 | 0 |
| NAPG | NAPG | Q99747 | Gamma-soluble NSF attachment protein | chr18 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 35 | 56 | 3 | 3 | 0 |
| NBAS | NBAS | A2RRP1 | NBAS subunit of NRZ tethering complex | chr2 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 365 | 246 | 41 | 41 | 5 |
| NCAPD3 | NCAPD3 | P42695 | Condensin-2 complex subunit D3 | chr11 | Not Cancer Driver | No | 1 | hippie | 193 | 304 | 42 | 42 | 1 |
| NDUFS1_ENST00000449699 | NDUFS1 | P28331 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 40 | 3 | 3 | 2 |
| NEMP1 | NEMP1 | O14524 | Nuclear envelope integral membrane protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 32 | 36 | 5 | 5 | 0 |
| NMRAL1 | NMRAL1 | Q9HBL8 | NmrA-like family domain-containing protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 39 | 14 | 3 | 3 | 0 |
| NOC4L | NOC4L | Q9BVI4 | Nucleolar complex protein 4 homolog | chr12 | Not Cancer Driver | No | 3 | hippie, biogrid | 63 | 41 | 1 | 1 | 0 |
| NOP14 | NOP14 | P78316 | Nucleolar protein 14 | chr4 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 87 | 521 | 46 | 46 | 0 |
| NPC1 | NPC1 | O15118 | NPC intracellular cholesterol transporter 1 | chr18 | Not Cancer Driver | No | 1 | hippie | 155 | 24 | 0 | 0 | 150 |
| NRAS | NRAS | P01111 | GTPase NRas | chr1 | Census, Compendium | Yes | 1 | hippie, biogrid | 284 | 10 | 0 | 0 | 14 |
| NRSN1 | NRSN1 | Q8IZ57 | Neurensin-1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 17 | 9 | 9 | 0 |
| NSF | NSF | P46459 | Vesicle-fusing ATPase | chr17 | Not Cancer Driver | No | 2 | hippie, biogrid | 47 | 84 | 3 | 3 | 2 |
| NSG1_ENST00000513555 | NSG1 | P42857 | Neuronal vesicle trafficking-associated protein 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 36 | 29 | 9 | 9 | 0 |
| OPN4_ENST00000241891 | OPN4 | Q9UHM6 | Melanopsin | chr10 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 84 | 88 | 9 | 9 | 0 |
| OPTN_ENST00000263036 | OPTN | Q96CV9 | Optineurin | chr10 | Not Cancer Driver | No | 3 | hippie, biogrid | 58 | 470 | 51 | 51 | 6 |
| PDZK1IP1_ENST00000371885 | PDZK1IP1 | Q13113 | PDZK1-interacting protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 22 | 21 | 0 | 0 | 0 |
| PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
| PLPPR2_ENST00000251473 | PLPPR2 | Q96GM1 | Phospholipid phosphatase-related protein type 2 | chr19 | Not Cancer Driver | No | 1 | hippie | 55 | 55 | 7 | 7 | 0 |
| PMAIP1 | PMAIP1 | Q13794 | Phorbol-12-myristate-13-acetate-induced protein 1 | chr18 | Not Cancer Driver | No | 1 | hippie | 2 | 23 | 1 | 1 | 0 |
| PQLC1 | SLC66A2 | Q8N2U9 | Solute carrier family 66 member 2 | chr18 | Not Cancer Driver | No | 1 | intact | 35 | 11 | 0 | 0 | 0 |
| PRMT9 | PRMT9 | Q6P2P2 | Protein arginine N-methyltransferase 9 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 84 | 63 | 4 | 4 | 0 |
| PRNP | PRNP | P04156 | Major prion protein | chr20 | Not Cancer Driver | No | 1 | hippie | 36 | 115 | 7 | 7 | 18 |
| RAB11A | RAB11A | P62491 | Ras-related protein Rab-11A | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 43 | 4 | 4 | 0 |
| RAB1A | RAB1A | P62820 | Ras-related protein Rab-1A | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 38 | 2 | 2 | 0 |
| RAB1B | RAB1B | Q9H0U4 | Ras-related protein Rab-1B | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 40 | 3 | 3 | 0 |
| RAB35 | RAB35 | Q15286 | Ras-related protein Rab-35 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 25 | 2 | 2 | 0 |
| RAB3B | RAB3B | P20337 | Ras-related protein Rab-3B | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 25 | 6 | 6 | 0 |
| RAB4A | RAB4A | P20338 | Ras-related protein Rab-4A | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 32 | 11 | 11 | 0 |
| RAB5A | RAB5A | P20339 | Ras-related protein Rab-5A | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 65 | 15 | 15 | 0 |
| RAB5C_ENST00000393860 | RAB5C | P51148 | Ras-related protein Rab-5C | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 50 | 4 | 4 | 0 |
| RAB7A | RAB7A | P51149 | Ras-related protein Rab-7a | chr3 | Not Cancer Driver | No | 1 | biogrid | 27 | 11 | 0 | 0 | 4 |
| RAB9A | RAB9A | P51151 | Ras-related protein Rab-9A | chrX | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 18 | 21 | 1 | 1 | 0 |
| RAC2 | RAC2 | P15153 | Ras-related C3 botulinum toxin substrate 2 | chr22 | Not Cancer Driver | No | 1 | hippie | 31 | 0 | 0 | 0 | 2 |
| RAC3 | RAC3 | P60763 | Ras-related C3 botulinum toxin substrate 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 4 |
| RAP1B_ENST00000393436 | RAP1B | P61224 | Ras-related protein Rap-1b | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 14 | 3 | 3 | 0 |
| RER1 | RER1 | O15258 | Protein RER1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 15 | 3 | 3 | 0 |
| RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | Census, Compendium | Yes | 1 | hippie | 99 | 46 | 13 | 13 | 2 |
| RHOB | RHOB | P62745 | Rho-related GTP-binding protein RhoB | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 19 | 2 | 2 | 0 |
| RHOH_ENST00000617441 | RHOH | Q15669 | Rho-related GTP-binding protein RhoH | chr4 | Census | Yes | 1 | hippie | 41 | 12 | 3 | 3 | 0 |
| RHOJ | RHOJ | Q9H4E5 | Rho-related GTP-binding protein RhoJ | chr14 | Not Cancer Driver | No | 1 | hippie | 39 | 0 | 0 | 0 | 0 |
| RHOQ | RHOQ | P17081 | Rho-related GTP-binding protein RhoQ | chr2 | Not Cancer Driver | No | 1 | hippie | 25 | 0 | 0 | 0 | 0 |
| RHOU | RHOU | Q7L0Q8 | Rho-related GTP-binding protein RhoU | chr1 | Not Cancer Driver | No | 1 | hippie | 34 | 63 | 6 | 6 | 0 |
| RIC3 | RIC3 | Q7Z5B4 | Protein RIC-3 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 72 | 281 | 62 | 62 | 0 |
| RND1 | RND1 | Q92730 | Rho-related GTP-binding protein Rho6 | chr12 | Not Cancer Driver | No | 1 | hippie | 45 | 9 | 1 | 1 | 0 |
| RNF13_ENST00000392894 | RNF13 | O43567 | E3 ubiquitin-protein ligase RNF13 | chr3 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 45 | 107 | 17 | 17 | 2 |
| RNF149 | RNF149 | Q8NC42 | E3 ubiquitin-protein ligase RNF149 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 102 | 10 | 10 | 0 |
| RNF4 | RNF4 | P78317 | E3 ubiquitin-protein ligase RNF4 | chr4 | Not Cancer Driver | No | 1 | hippie | 14 | 117 | 7 | 7 | 0 |
| SCFD2 | SCFD2 | Q8WU76 | Sec1 family domain-containing protein 2 | chr4 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 96 | 24 | 4 | 4 | 0 |
| SCGN | SCGN | O76038 | Secretagogin | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 77 | 12 | 1 | 1 | 0 |
| SEC11C | SEC11C | Q9BY50 | Signal peptidase complex catalytic subunit SEC11C | chr18 | Not Cancer Driver | No | 1 | intact, hippie | 24 | 3 | 0 | 0 | 0 |
| SLC10A6 | SLC10A6 | Q3KNW5 | Solute carrier family 10 member 6 | chr4 | Not Cancer Driver | No | 1 | hippie | 61 | 38 | 7 | 7 | 0 |
| SLC7A1 | SLC7A1 | P30825 | High affinity cationic amino acid transporter 1 | chr13 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 89 | 17 | 3 | 3 | 0 |
| SNAP23 | SNAP23 | O00161 | Synaptosomal-associated protein 23 | chr15 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 18 | 179 | 16 | 16 | 0 |
| SNAP25 | SNAP25 | P60880 | Synaptosomal-associated protein 25 | chr20 | Not Cancer Driver | No | 1 | hippie | 61 | 176 | 49 | 49 | 1 |
| SNAP29 | SNAP29 | O95721 | Synaptosomal-associated protein 29 | chr22 | Not Cancer Driver | No | 4 | hippie, biogrid | 21 | 246 | 20 | 20 | 0 |
| SNAP47_ENST00000366759 | SNAP47 | Q5SQN1 | Synaptosomal-associated protein 47 | chr1 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 51 | 192 | 20 | 20 | 0 |
| STX10 | STX10 | O60499 | Syntaxin-10 | chr19 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 29 | 77 | 7 | 7 | 0 |
| STX18 | STX18 | Q9P2W9 | Syntaxin-18 | chr4 | Not Cancer Driver | No | 3 | hippie, biogrid | 28 | 174 | 15 | 15 | 0 |
| STX1A | STX1A | Q16623 | Syntaxin-1A | chr7 | Not Cancer Driver | No | 1 | hippie | 35 | 136 | 11 | 11 | 0 |
| STX2 | STX2 | P32856 | Syntaxin-2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 43 | 140 | 25 | 25 | 0 |
| STX4 | STX4 | Q12846 | Syntaxin-4 | chr16 | Not Cancer Driver | No | 4 | hippie, biogrid | 50 | 152 | 20 | 20 | 0 |
| STX5 | STX5 | Q13190 | Syntaxin-5 | chr11 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 36 | 147 | 14 | 14 | 0 |
| STX6 | STX6 | O43752 | Syntaxin-6 | chr1 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 33 | 78 | 11 | 11 | 0 |
| STX7 | STX7 | O15400 | Syntaxin-7 | chr6 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 29 | 164 | 14 | 14 | 0 |
| STX8 | STX8 | Q9UNK0 | Syntaxin-8 | chr17 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 32 | 98 | 10 | 10 | 0 |
| STXBP5 | STXBP5 | Q5T5C0 | Syntaxin-binding protein 5 | chr6 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 128 | 344 | 46 | 46 | 0 |
| STXBP5L | STXBP5L | Q9Y2K9 | Syntaxin-binding protein 5-like | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 358 | 292 | 101 | 101 | 0 |
| STXBP6_ENST00000419632 | STXBP6 | Q8NFX7 | Syntaxin-binding protein 6 | chr14 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 33 | 51 | 6 | 6 | 0 |
| TAF9 | TAF9 | Q16594 | Transcription initiation factor TFIID subunit 9 | chr5 | Not Cancer Driver | No | 1 | hippie | 25 | 203 | 19 | 19 | 0 |
| TBC1D15 | TBC1D15 | Q8TC07 | TBC1 domain family member 15 | chr12 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 90 | 135 | 23 | 23 | 0 |
| TBC1D17 | TBC1D17 | Q9HA65 | TBC1 domain family member 17 | chr19 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 76 | 191 | 25 | 25 | 0 |
| TBK1 | TBK1 | Q9UHD2 | Serine/threonine-protein kinase TBK1 | chr12 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 101 | 42 | 5 | 5 | 12 |
| TFRC_ENST00000392396 | TFRC | P02786 | Transferrin receptor protein 1 | chr3 | Census | Yes | 1 | hippie, biogrid | 89 | 80 | 6 | 6 | 1 |
| TGOLN2_ENST00000377386 | TGOLN2 | O43493 | Trans-Golgi network integral membrane protein 2 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 51 | 399 | 46 | 46 | 0 |
| TIMMDC1 | TIMMDC1 | Q9NPL8 | Complex I assembly factor TIMMDC1, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie | 44 | 50 | 6 | 6 | 0 |
| TM9SF4 | TM9SF4 | Q92544 | Transmembrane 9 superfamily member 4 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 76 | 39 | 4 | 4 | 0 |
| TMEM14B_ENST00000379542 | TMEM14B | Q9NUH8 | Transmembrane protein 14B | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 13 | 0 | 0 | 0 | 0 |
| TMEM167B | TMEM167B | Q9NRX6 | Protein kish-B | chr1 | Not Cancer Driver | No | 1 | hippie | 7 | 0 | 0 | 0 | 0 |
| TMEM17 | TMEM17 | Q86X19 | Transmembrane protein 17 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 22 | 14 | 2 | 2 | 0 |
| TMEM216 | TMEM216 | Q9P0N5 | Transmembrane protein 216 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 11 | 0 | 0 | 0 | 7 |
| TMEM258 | TMEM258 | P61165 | Transmembrane protein 258 | chr11 | Not Cancer Driver | No | 1 | hippie | 13 | 0 | 0 | 0 | 0 |
| TMEM31 | TMEM31 | Q5JXX7 | Transmembrane protein 31 | chrX | Not Cancer Driver | No | 1 | hippie | 26 | 61 | 10 | 10 | 0 |
| TMEM56 | TLCD4 | Q96MV1 | TLC domain-containing protein 4 | chr1 | Not Cancer Driver | No | 1 | intact | 32 | 0 | 0 | 0 | 0 |
| TMEM86B | TMEM86B | Q8N661 | Lysoplasmalogenase | chr19 | Not Cancer Driver | No | 1 | hippie | 15 | 1 | 0 | 0 | 0 |
| TMX2 | TMX2 | Q9Y320 | Thioredoxin-related transmembrane protein 2 | chr11 | Not Cancer Driver | No | 1 | hippie | 47 | 40 | 5 | 5 | 3 |
| TNFRSF10B | TNFRSF10B | O14763 | Tumor necrosis factor receptor superfamily member 10B | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 44 | 190 | 19 | 19 | 0 |
| TNFRSF10C | TNFRSF10C | O14798 | Tumor necrosis factor receptor superfamily member 10C | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 120 | 30 | 30 | 0 |
| TRDN | TRDN | Q13061 | Triadin | chr6 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 129 | 639 | 102 | 102 | 1 |
| TXLNA_ENST00000373610 | TXLNA | P40222 | Alpha-taxilin | chr1 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 68 | 481 | 59 | 59 | 0 |
| UBQLN2 | UBQLN2 | Q9UHD9 | Ubiquilin-2 | chrX | Not Cancer Driver | No | 1 | hippie | 82 | 581 | 79 | 79 | 8 |
| USE1 | USE1 | Q9NZ43 | Vesicle transport protein USE1 | chr19 | Not Cancer Driver | No | 3 | hippie, biogrid | 31 | 101 | 19 | 19 | 0 |
| VAMP2_ENST00000316509 | VAMP2 | P63027 | Vesicle-associated membrane protein 2 | chr17 | Not Cancer Driver | No | 3 | hippie, biogrid | 7 | 47 | 4 | 4 | 3 |
| VAMP3 | VAMP3 | Q15836 | Vesicle-associated membrane protein 3 | chr1 | Not Cancer Driver | No | 3 | hippie, biogrid | 11 | 17 | 1 | 1 | 0 |
| VAMP4 | VAMP4 | O75379 | Vesicle-associated membrane protein 4 | chr1 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 9 | 80 | 6 | 6 | 0 |
| VAMP5 | VAMP5 | O95183 | Vesicle-associated membrane protein 5 | chr2 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 17 | 19 | 1 | 1 | 0 |
| VAMP7_ENST00000286448 | VAMP7 | P51809 | Vesicle-associated membrane protein 7 | chrX | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 38 | 4 | 1 | 1 | 0 |
| VAMP8 | VAMP8 | Q9BV40 | Vesicle-associated membrane protein 8 | chr2 | Not Cancer Driver | No | 3 | hippie, biogrid | 9 | 27 | 0 | 0 | 0 |
| VDAC1_ENST00000395047 | VDAC1 | P21796 | Voltage-dependent anion-selective channel protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 36 | 4 | 4 | 0 |
| VDAC2_ENST00000543351 | VDAC2 | P45880 | Voltage-dependent anion-selective channel protein 2 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 9 | 1 | 1 | 0 |
| VDAC3_ENST00000022615 | VDAC3 | Q9Y277 | Voltage-dependent anion-selective channel protein 3 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 0 | 0 | 0 | 0 |
| VPS45_ENST00000644510 | VPS45 | Q9NRW7 | Vacuolar protein sorting-associated protein 45 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 66 | 57 | 5 | 5 | 2 |
| VPS50 | VPS50 | Q96JG6 | Syndetin | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 175 | 171 | 32 | 32 | 0 |
| VTI1A | VTI1A | Q96AJ9 | Vesicle transport through interaction with t-SNAREs homolog 1A | chr10 | Census | Yes | 4 | intact, hippie, biogrid | 21 | 138 | 13 | 13 | 0 |
| VTI1B | VTI1B | Q9UEU0 | Vesicle transport through interaction with t-SNAREs homolog 1B | chr14 | Not Cancer Driver | No | 3 | hippie, biogrid | 25 | 192 | 20 | 20 | 0 |
| YKT6 | YKT6 | O15498 | Synaptobrevin homolog YKT6 | chr7 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 19 | 21 | 2 | 2 | 0 |
| ZDHHC12 | ZDHHC12 | Q96GR4 | Palmitoyltransferase ZDHHC12 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 13 | 1 | 1 | 0 |
| ZKSCAN1 | ZKSCAN1 | P17029 | Zinc finger protein with KRAB and SCAN domains 1 | chr7 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 68 | 346 | 41 | 41 | 0 |
| ZNF219 | ZNF219 | Q9P2Y4 | Zinc finger protein 219 | chr14 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 44 | 628 | 37 | 37 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|