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STUB1 ,STUB1 ,Q9UNE7
  • Uniprot Accession= Q9UNE7
  • Ensembl Transcript= ENST00000219548.8
  • Uniprot Name= STUB1
  • Name= E3 ubiquitin-protein ligase CHIP
  • Chromosome= chr16
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 9
  • Number of Interaction partner in biogrid: 154
  • Number of Interaction partner in hippie: 555
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
A2M A2M P01023 Alpha-2-macroglobulin chr12 Not Cancer Driver No 1 hippie 260 144 22 22 0
ABCG2 ABCG2 Q9UNQ0 Broad substrate specificity ATP-binding cassette transporter ABCG2 chr4 Not Cancer Driver No 1 hippie 124 35 10 10 0
ABHD15 ABHD15 Q6UXT9 Protein ABHD15 chr17 Not Cancer Driver No 2 hippie, biogrid 50 41 3 3 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 Census, Compendium Yes 1 hippie 139 604 73 73 2
ACAT1 ACAT1 P24752 Acetyl-CoA acetyltransferase, mitochondrial chr11 Not Cancer Driver No 1 hippie 45 32 1 1 10
ACBD5_ENST00000375888 ACBD5 Q5T8D3 Acyl-CoA-binding domain-containing protein 5 chr10 Not Cancer Driver No 1 hippie, biogrid 65 330 45 45 0
ACD_ENST00000620761 ACD Q96AP0 Adrenocortical dysplasia protein homolog chr16 Not Cancer Driver No 1 hippie 49 256 34 34 1
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX Not Cancer Driver No 1 hippie, biogrid 104 68 5 5 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie 112 43 5 5 5
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 51 6 2 2 0
ACTR3 ACTR3 P61158 Actin-related protein 3 chr2 Not Cancer Driver No 1 hippie 32 16 2 2 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 Census, Compendium Yes 1 hippie 78 21 8 8 8
ADCK1 ADCK1 Q86TW2 AarF domain-containing protein kinase 1 chr14 Not Cancer Driver No 1 hippie, biogrid 82 6 3 3 0
ADCK2 ADCK2 Q7Z695 Uncharacterized aarF domain-containing protein kinase 2 chr7 Not Cancer Driver No 1 hippie, biogrid 62 9 1 1 0
ADCY3_ENST00000260600 ADCY3 O60266 Adenylate cyclase type 3 chr2 Not Cancer Driver No 1 hippie, biogrid 135 185 18 18 0
ADRM1 ADRM1 Q16186 Proteasomal ubiquitin receptor ADRM1 chr20 Not Cancer Driver No 1 hippie 49 296 40 40 0
AGO1 AGO1 Q9UL18 Protein argonaute-1 chr1 Not Cancer Driver No 2 hippie, biogrid 126 87 11 11 0
AHCYL1 AHCYL1 O43865 S-adenosylhomocysteine hydrolase-like protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 58 108 10 10 0
AHR AHR P35869 Aryl hydrocarbon receptor chr7 Not Cancer Driver No 1 hippie 129 351 75 75 0
AIMP2 AIMP2 Q13155 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 chr7 Not Cancer Driver No 1 hippie 46 61 8 8 0
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 107 537 67 67 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 2 intact, hippie 108 158 24 24 4
ALDH1L1_ENST00000393434 ALDH1L1 O75891 Cytosolic 10-formyltetrahydrofolate dehydrogenase chr3 Not Cancer Driver No 1 hippie 159 87 19 19 0
ALDH3B1 ALDH3B1 P43353 Aldehyde dehydrogenase family 3 member B1 chr11 Not Cancer Driver No 1 hippie, biogrid 36 23 6 6 0
ALDH9A1 ALDH9A1 P49189 4-trimethylaminobutyraldehyde dehydrogenase chr1 Not Cancer Driver No 1 hippie 57 16 0 0 0
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 Not Cancer Driver No 1 hippie 173 788 103 103 0
ANAPC2 ANAPC2 Q9UJX6 Anaphase-promoting complex subunit 2 chr9 Not Cancer Driver No 1 hippie, biogrid 104 146 26 26 0
ANKK1 ANKK1 Q8NFD2 Ankyrin repeat and protein kinase domain-containing protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 103 90 7 7 0
AP5Z1 AP5Z1 O43299 AP-5 complex subunit zeta-1 chr7 Not Cancer Driver No 1 hippie, biogrid 98 94 11 11 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie 34 103 14 14 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
AQP2 AQP2 P41181 Aquaporin-2 chr12 Not Cancer Driver No 1 hippie 52 31 3 3 28
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 196 443 88 88 169
ARAF_ENST00000377045 ARAF P10398 Serine/threonine-protein kinase A-Raf chrX Census, Compendium Yes 1 hippie 84 181 32 32 0
ARC ARC Q7LC44 Activity-regulated cytoskeleton-associated protein chr8 Not Cancer Driver No 1 hippie 64 194 29 29 0
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie 18 5 0 0 0
ARNTL ARNTL O00327 Aryl hydrocarbon receptor nuclear translocator-like protein 1 chr11 Not Cancer Driver No 1 hippie 71 332 40 40 0
ARRB1 ARRB1 P49407 Beta-arrestin-1 chr11 Not Cancer Driver No 1 hippie 49 154 13 13 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 Not Cancer Driver No 1 hippie 46 122 22 22 0
ASB10 ASB10 Q8WXI3 Ankyrin repeat and SOCS box protein 10 chr7 Not Cancer Driver No 1 hippie 81 113 24 24 0
ASB4 ASB4 Q9Y574 Ankyrin repeat and SOCS box protein 4 chr7 Not Cancer Driver No 1 hippie 82 19 1 1 0
ASPM ASPM Q8IZT6 Abnormal spindle-like microcephaly-associated protein chr1 Not Cancer Driver No 1 hippie 554 424 67 67 0
ATCAY ATCAY Q86WG3 Caytaxin chr19 Not Cancer Driver No 1 hippie 75 188 38 38 1
ATG101 ATG101 Q9BSB4 Autophagy-related protein 101 chr12 Not Cancer Driver No 1 hippie 21 5 0 0 0
ATL1 ATL1 Q8WXF7 Atlastin-1 chr14 Not Cancer Driver No 1 hippie 72 55 12 12 19
ATP6AP2 ATP6AP2 O75787 Renin receptor chrX Not Cancer Driver No 1 hippie 56 0 0 0 2
ATXN1 ATXN1 P54253 Ataxin-1 chr6 Not Cancer Driver No 1 hippie 193 604 168 168 0
ATXN3 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 hippie 46 181 24 24 0
AVPR2_ENST00000337474 AVPR2 P30518 Vasopressin V2 receptor chrX Not Cancer Driver No 1 hippie 58 56 7 7 84
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 Not Cancer Driver No 2 hippie, biogrid 168 341 64 64 0
BACE1 BACE1 P56817 Beta-secretase 1 chr11 Not Cancer Driver No 1 hippie 55 53 5 5 0
BAG1 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 Not Cancer Driver No 1 hippie 29 195 9 9 0
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 2 hippie, biogrid 17 112 9 9 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie 57 571 57 57 7
BAG4 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 Not Cancer Driver No 1 hippie 55 402 49 49 0
BAG5_ENST00000299204 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 Not Cancer Driver No 1 hippie 37 63 7 7 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 Not Cancer Driver No 1 hippie 98 861 79 79 0
BCR BCR P11274 Breakpoint cluster region protein chr22 Census, Compendium Yes 1 hippie 146 603 69 69 0
BDKRB2 BDKRB2 P30411 B2 bradykinin receptor chr14 Not Cancer Driver No 1 hippie 81 0 0 0 0
BIRC2 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 Not Cancer Driver No 1 hippie 69 83 9 9 0
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 Not Cancer Driver No 1 hippie 91 69 18 18 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BRD8 BRD8 Q9H0E9 Bromodomain-containing protein 8 chr5 Not Cancer Driver No 1 hippie 189 934 147 147 0
BSG BSG P35613 Basigin chr19 Not Cancer Driver No 1 hippie, biogrid 43 123 17 17 0
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 Not Cancer Driver No 1 hippie 80 45 4 4 0
C3orf38 C3orf38 Q5JPI3 Uncharacterized protein C3orf38 chr3 Not Cancer Driver No 1 hippie, biogrid 40 50 6 6 0
CACYBP CACYBP Q9HB71 Calcyclin-binding protein chr1 Not Cancer Driver No 1 hippie 27 92 10 10 0
CAD CAD P27708 CAD protein chr2 Not Cancer Driver No 1 hippie 287 368 52 52 1
CAMK2A_ENST00000348628 CAMK2A Q9UQM7 Calcium/calmodulin-dependent protein kinase type II subunit alpha chr5 Not Cancer Driver No 1 hippie 83 62 10 10 7
CAPN2 CAPN2 P17655 Calpain-2 catalytic subunit chr1 Not Cancer Driver No 1 hippie 81 46 11 11 0
CARD11 CARD11 Q9BXL7 Caspase recruitment domain-containing protein 11 chr7 Census, Compendium Yes 1 hippie 303 530 140 140 5
CASP6 CASP6 P55212 Caspase-6 chr4 Not Cancer Driver No 1 hippie 28 24 4 4 0
CCL28 CCL28 Q9NRJ3 C-C motif chemokine 28 chr5 Not Cancer Driver No 1 hippie 17 48 8 8 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 106 221 23 23 3
CCT5 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 Not Cancer Driver No 1 hippie, biogrid 83 72 10 10 1
CCT7 CCT7 Q99832 T-complex protein 1 subunit eta chr2 Not Cancer Driver No 1 hippie, biogrid 59 36 6 6 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 Not Cancer Driver No 1 hippie 69 56 11 11 0
CD81 CD81 P60033 CD81 antigen chr11 Not Cancer Driver No 1 hippie 28 0 0 0 0
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 1 hippie 52 214 31 31 0
CDC37L1 CDC37L1 Q7L3B6 Hsp90 co-chaperone Cdc37-like 1 chr9 Not Cancer Driver No 1 hippie 36 122 10 10 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CDK18_ENST00000360066 CDK18 Q07002 Cyclin-dependent kinase 18 chr1 Not Cancer Driver No 1 hippie 64 132 17 17 0
CDK20 CDK20 Q8IZL9 Cyclin-dependent kinase 20 chr9 Not Cancer Driver No 2 hippie, biogrid 36 32 1 1 0
CDK4 CDK4 P11802 Cyclin-dependent kinase 4 chr12 Census, Compendium Yes 1 hippie 52 52 5 5 3
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 Not Cancer Driver No 1 hippie 48 5 1 1 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 Census, Compendium Yes 1 hippie 48 121 30 30 0
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 Not Cancer Driver No 1 hippie 40 44 2 2 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 hippie 287 145 18 18 151
CHAT CHAT P28329 Choline O-acetyltransferase chr10 Not Cancer Driver No 1 hippie 155 193 24 24 10
CHUK CHUK O15111 Inhibitor of nuclear factor kappa-B kinase subunit alpha chr10 Not Cancer Driver No 1 hippie 74 116 9 9 0
CIC CIC Q96RK0 Protein capicua homolog chr19 Census, Compendium Yes 1 hippie 276 1550 266 266 0
CIP2A CIP2A Q8TCG1 Protein CIP2A chr3 Not Cancer Driver No 1 hippie 118 240 31 31 0
CISD2 CISD2 Q8N5K1 CDGSH iron-sulfur domain-containing protein 2 chr4 Not Cancer Driver No 1 hippie 11 7 0 0 0
CLCN2 CLCN2 P51788 Chloride channel protein 2 chr3 Not Cancer Driver No 1 hippie 124 224 38 38 8
CLEC1B CLEC1B Q9P126 C-type lectin domain family 1 member B chr12 Not Cancer Driver No 1 hippie 50 3 0 0 0
CLK3 CLK3 P49761 Dual specificity protein kinase CLK3 chr15 Not Cancer Driver No 1 hippie, biogrid 67 295 27 27 0
CLOCK CLOCK O15516 Circadian locomoter output cycles protein kaput chr4 Not Cancer Driver No 1 hippie 83 458 38 38 0
COIL COIL P38432 Coilin chr17 Not Cancer Driver No 1 hippie, biogrid 61 385 42 42 0
COMT COMT P21964 Catechol O-methyltransferase chr22 Not Cancer Driver No 1 hippie 21 5 0 0 0
CPSF3 CPSF3 Q9UKF6 Cleavage and polyadenylation specificity factor subunit 3 chr2 Not Cancer Driver No 1 hippie, biogrid 78 56 9 9 0
CSNK1A1_ENST00000377843 CSNK1A1 P48729 Casein kinase I isoform alpha chr5 Not Cancer Driver No 1 hippie 44 46 3 3 0
CSNK1G2 CSNK1G2 P78368 Casein kinase I isoform gamma-2 chr19 Not Cancer Driver No 1 hippie 43 111 13 13 0
CTBP2_ENST00000494626 CTBP2 P56545 C-terminal-binding protein 2 chr10 Not Cancer Driver No 1 hippie 48 94 4 4 0
CTCFL_ENST00000371196 CTCFL Q8NI51 Transcriptional repressor CTCFL chr20 Not Cancer Driver No 1 hippie 136 266 61 61 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
CTSL CTSL P07711 Procathepsin L chr9 Not Cancer Driver No 1 hippie, biogrid 47 34 4 4 0
CUL4B CUL4B Q13620 Cullin-4B chrX Not Cancer Driver No 1 hippie 138 207 38 38 2
CXADR CXADR P78310 Coxsackievirus and adenovirus receptor chr21 Not Cancer Driver No 1 hippie, biogrid 51 98 19 19 0
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
CYP2E1_ENST00000252945 CYP2E1 P05181 Cytochrome P450 2E1 chr10 Not Cancer Driver No 1 hippie 87 21 6 6 0
CYP2W1 CYP2W1 Q8TAV3 Cytochrome P450 2W1 chr7 Not Cancer Driver No 1 hippie, biogrid 51 55 6 6 0
CYP3A4 CYP3A4 P08684 Cytochrome P450 3A4 chr7 Not Cancer Driver No 1 hippie 91 22 2 2 1
CYTH1_ENST00000446868 CYTH1 Q15438 Cytohesin-1 chr17 Not Cancer Driver No 1 hippie 59 93 15 15 0
DAPK1_ENST00000622514 DAPK1 P53355 Death-associated protein kinase 1 chr9 Not Cancer Driver No 2 hippie, biogrid 193 114 11 11 0
DAXX_ENST00000266000 DAXX Q9UER7 Death domain-associated protein 6 chr6 Census, Compendium Yes 1 hippie 106 549 81 81 0
DDIAS DDIAS Q8IXT1 DNA damage-induced apoptosis suppressor protein chr11 Not Cancer Driver No 1 hippie 125 370 59 59 0
DDX39B_ENST00000458640 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 Not Cancer Driver No 1 hippie 49 34 8 8 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DDX60 DDX60 Q8IY21 Probable ATP-dependent RNA helicase DDX60 chr4 Not Cancer Driver No 1 intact, hippie 224 131 12 12 0
DHFR2_ENST00000314636 DHFR2 Q86XF0 Dihydrofolate reductase 2, mitochondrial chr3 Not Cancer Driver No 1 hippie 25 20 0 0 0
DHX30 DHX30 Q7L2E3 ATP-dependent RNA helicase DHX30 chr3 Not Cancer Driver No 1 hippie, biogrid 165 260 40 40 6
DNAAF4_ENST00000348518 DNAAF4 Q8WXU2 Dynein axonemal assembly factor 4 chr15 Not Cancer Driver No 1 hippie 63 177 20 20 0
DNAJA1 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 Not Cancer Driver No 1 hippie, biogrid 37 153 16 16 0
DNAJA2 DNAJA2 O60884 DnaJ homolog subfamily A member 2 chr16 Not Cancer Driver No 1 hippie, biogrid 50 174 27 27 0
DNAJA3 DNAJA3 Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial chr16 Not Cancer Driver No 1 hippie 50 152 21 21 0
DNAJA4_ENST00000394852 DNAJA4 Q8WW22 DnaJ homolog subfamily A member 4 chr15 Not Cancer Driver No 1 hippie, biogrid 43 110 6 6 0
DNAJB1 DNAJB1 P25685 DnaJ homolog subfamily B member 1 chr19 Census, Compendium Yes 1 hippie 35 196 26 26 0
DNAJB11_ENST00000265028 DNAJB11 Q9UBS4 DnaJ homolog subfamily B member 11 chr3 Not Cancer Driver No 1 hippie, biogrid 52 141 21 21 2
DNAJB12_ENST00000444643 DNAJB12 Q9NXW2 DnaJ homolog subfamily B member 12 chr10 Not Cancer Driver No 1 hippie, biogrid 43 227 20 20 0
DNAJB14 DNAJB14 Q8TBM8 DnaJ homolog subfamily B member 14 chr4 Not Cancer Driver No 1 hippie, biogrid 38 200 19 19 0
DNAJB2 DNAJB2 P25686 DnaJ homolog subfamily B member 2 chr2 Not Cancer Driver No 1 hippie, biogrid 51 239 40 40 1
DNAJB5_ENST00000312316 DNAJB5 O75953 DnaJ homolog subfamily B member 5 chr9 Not Cancer Driver No 1 hippie, biogrid 49 147 18 18 0
DNAJB6 DNAJB6 O75190 DnaJ homolog subfamily B member 6 chr7 Not Cancer Driver No 2 hippie, biogrid 33 198 17 17 3
DNAJB8_ENST00000319153 DNAJB8 Q8NHS0 DnaJ homolog subfamily B member 8 chr3 Not Cancer Driver No 1 hippie, biogrid 64 92 30 30 0
DNAJC11 DNAJC11 Q9NVH1 DnaJ homolog subfamily C member 11 chr1 Not Cancer Driver No 1 hippie, biogrid 66 123 14 14 0
DNAJC12 DNAJC12 Q9UKB3 DnaJ homolog subfamily C member 12 chr10 Not Cancer Driver No 1 hippie, biogrid 29 124 17 17 1
DNAJC13 DNAJC13 O75165 DnaJ homolog subfamily C member 13 chr3 Not Cancer Driver No 2 hippie, biogrid 276 141 17 17 0
DNAJC16 DNAJC16 Q9Y2G8 DnaJ homolog subfamily C member 16 chr1 Not Cancer Driver No 1 hippie, biogrid 84 63 2 2 0
DNAJC18 DNAJC18 Q9H819 DnaJ homolog subfamily C member 18 chr5 Not Cancer Driver No 1 hippie, biogrid 40 82 12 12 0
DNAJC5 DNAJC5 Q9H3Z4 DnaJ homolog subfamily C member 5 chr20 Not Cancer Driver No 2 hippie, biogrid 23 46 6 6 1
DNAJC5B DNAJC5B Q9UF47 DnaJ homolog subfamily C member 5B chr8 Not Cancer Driver No 1 hippie, biogrid 64 31 7 7 0
DNAJC7 DNAJC7 Q99615 DnaJ homolog subfamily C member 7 chr17 Not Cancer Driver No 2 hippie, biogrid 41 102 9 9 0
DNM3_ENST00000355305 DNM3 Q9UQ16 Dynamin-3 chr1 Not Cancer Driver No 1 hippie 166 257 45 45 0
DPM1_ENST00000371588 DPM1 O60762 Dolichol-phosphate mannosyltransferase subunit 1 chr20 Not Cancer Driver No 1 hippie 38 29 6 6 3
DRD4 DRD4 P21917 D(4) dopamine receptor chr11 Not Cancer Driver No 1 hippie 26 109 0 0 0
DYNC1I1 DYNC1I1 O14576 Cytoplasmic dynein 1 intermediate chain 1 chr7 Not Cancer Driver No 1 hippie 146 255 60 60 0
DYNC1I2_ENST00000409773 DYNC1I2 Q13409 Cytoplasmic dynein 1 intermediate chain 2 chr2 Not Cancer Driver No 1 hippie 82 300 42 42 1
DYRK1B_ENST00000323039 DYRK1B Q9Y463 Dual specificity tyrosine-phosphorylation-regulated kinase 1B chr19 Not Cancer Driver No 1 hippie 77 319 38 38 2
DYRK4_ENST00000010132 DYRK4 Q9NR20 Dual specificity tyrosine-phosphorylation-regulated kinase 4 chr12 Not Cancer Driver No 1 hippie, biogrid 111 178 33 33 0
E2F8_ENST00000250024 E2F8 A0AVK6 Transcription factor E2F8 chr11 Not Cancer Driver No 1 hippie 132 582 85 85 0
EDEM1 EDEM1 Q92611 ER degradation-enhancing alpha-mannosidase-like protein 1 chr3 Not Cancer Driver No 1 hippie 54 141 5 5 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EIF2AK1 EIF2AK1 Q9BQI3 Eukaryotic translation initiation factor 2-alpha kinase 1 chr7 Not Cancer Driver No 1 hippie, biogrid 87 238 29 29 0
EIF4E_ENST00000450253 EIF4E P06730 Eukaryotic translation initiation factor 4E chr4 Not Cancer Driver No 1 hippie 26 54 6 6 0
EIF5A_ENST00000419711 EIF5A P63241 Eukaryotic translation initiation factor 5A-1 chr17 Not Cancer Driver No 1 hippie 37 21 5 5 5
EIPR1_ENST00000382125 EIPR1 Q53HC9 EARP and GARP complex-interacting protein 1 chr2 Not Cancer Driver No 1 hippie 52 71 4 4 0
ELP4_ENST00000640961 ELP4 Q96EB1 Elongator complex protein 4 chr11 Not Cancer Driver No 1 hippie, biogrid 60 55 4 4 0
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 Not Cancer Driver No 1 hippie 11 61 1 1 0
ENO1 ENO1 P06733 Alpha-enolase chr1 Not Cancer Driver No 1 hippie 51 21 2 2 0
ENTR1 ENTR1 Q96C92 Endosome-associated-trafficking regulator 1 chr9 Not Cancer Driver No 1 hippie 64 267 38 38 0
EPAS1 EPAS1 Q99814 Endothelial PAS domain-containing protein 1 chr2 Census, Compendium Yes 1 hippie 120 449 53 53 6
EPM2A EPM2A O95278 Laforin chr6 Not Cancer Driver No 1 hippie 29 46 1 1 19
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 1 hippie 275 314 41 41 1
ERCC3 ERCC3 P19447 General transcription and DNA repair factor IIH helicase subunit XPB chr2 Census, Compendium Yes 1 hippie 92 208 22 22 2
ERG_ENST00000288319 ERG P11308 Transcriptional regulator ERG chr21 Census, Compendium Yes 1 hippie 95 296 54 54 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 Not Cancer Driver No 1 hippie 125 250 28 28 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
ESRRA_ENST00000000442 ESRRA P11474 Steroid hormone receptor ERR1 chr11 Compendium Yes 1 hippie 37 101 9 9 0
EVC2 EVC2 Q86UK5 Limbin chr4 Not Cancer Driver No 1 hippie 240 335 71 71 2
EXOC5 EXOC5 O00471 Exocyst complex component 5 chr14 Not Cancer Driver No 1 hippie 59 57 4 4 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 Census, Compendium Yes 1 hippie 120 284 44 44 11
F12 F12 P00748 Coagulation factor XII chr5 Not Cancer Driver No 1 hippie, biogrid 53 104 9 9 13
F3 F3 P13726 Tissue factor chr1 Not Cancer Driver No 1 hippie 28 61 7 7 0
FADD FADD Q13158 FAS-associated death domain protein chr11 Not Cancer Driver No 1 hippie 26 45 10 10 1
FAF1 FAF1 Q9UNN5 FAS-associated factor 1 chr1 Not Cancer Driver No 1 hippie 83 241 34 34 0
FBXO10 FBXO10 Q9UK96 F-box only protein 10 chr9 Not Cancer Driver No 1 hippie, biogrid 106 223 23 23 0
FBXO2 FBXO2 Q9UK22 F-box only protein 2 chr1 Not Cancer Driver No 1 hippie 21 75 1 1 0
FBXO24_ENST00000241071 FBXO24 O75426 F-box only protein 24 chr7 Not Cancer Driver No 1 hippie 119 55 10 10 0
FBXO27 FBXO27 Q8NI29 F-box only protein 27 chr19 Not Cancer Driver No 1 hippie 37 33 3 3 0
FKBP6 FKBP6 O75344 Inactive peptidyl-prolyl cis-trans isomerase FKBP6 chr7 Not Cancer Driver No 1 hippie 75 17 1 1 0
FLCN FLCN Q8NFG4 Folliculin chr17 Census, Compendium Yes 1 hippie 59 157 19 19 5
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX Not Cancer Driver No 1 hippie 124 327 70 70 3
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 Census, Compendium Yes 1 hippie 81 584 75 75 0
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX Not Cancer Driver No 1 hippie 38 186 16 16 10
FXR1 FXR1 P51114 Fragile X mental retardation syndrome-related protein 1 chr3 Not Cancer Driver No 1 hippie 88 312 53 53 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 92 70 13 13 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 74 184 30 30 0
G6PD_ENST00000621232 G6PD P11413 Glucose-6-phosphate 1-dehydrogenase chrX Not Cancer Driver No 1 hippie 86 28 3 3 58
GAL GAL P22466 Galanin peptides chr11 Not Cancer Driver No 1 hippie 17 36 2 2 1
GHR_ENST00000612382 GHR P10912 Growth hormone receptor chr5 Not Cancer Driver No 1 hippie 173 229 66 66 19
GLE1 GLE1 Q53GS7 mRNA export factor GLE1 chr9 Not Cancer Driver No 1 hippie 64 299 29 29 3
GNAS_ENST00000371075 GNAS O95467 Neuroendocrine secretory protein 55 chr20 Census, Compendium Yes 1 hippie 71 221 65 65 0
GPR37 GPR37 O15354 Prosaposin receptor GPR37 chr7 Not Cancer Driver No 1 hippie 124 200 42 42 0
GRK6_ENST00000355472 GRK6 P43250 G protein-coupled receptor kinase 6 chr5 Not Cancer Driver No 1 hippie, biogrid 65 68 10 10 0
GRN GRN P28799 Progranulin chr17 Not Cancer Driver No 1 hippie 76 29 6 6 1
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 Not Cancer Driver No 1 hippie 56 146 13 13 0
GUCY1A1_ENST00000513574 GUCY1A1 Q02108 Guanylate cyclase soluble subunit alpha-1 chr4 Not Cancer Driver No 1 hippie 181 54 8 8 0
GUCY1A2_ENST00000526355 GUCY1A2 P33402 Guanylate cyclase soluble subunit alpha-2 chr11 Not Cancer Driver No 1 hippie 191 187 48 48 0
GUCY1B1_ENST00000264424 GUCY1B1 Q02153 Guanylate cyclase soluble subunit beta-1 chr4 Not Cancer Driver No 1 hippie 103 83 20 20 0
HAVCR1_ENST00000339252 HAVCR1 Q96D42 Hepatitis A virus cellular receptor 1 chr5 Not Cancer Driver No 1 hippie 95 156 48 48 0
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 Not Cancer Driver No 1 hippie, biogrid 44 219 32 32 2
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 1 hippie 182 749 132 132 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX Not Cancer Driver No 1 hippie 178 409 59 59 0
HIF1AN HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 Not Cancer Driver No 1 hippie 37 77 9 9 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 Census Yes 1 hippie 118 435 51 51 0
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 Not Cancer Driver No 1 hippie 154 686 96 96 0
HMGN3_ENST00000344726 HMGN3 Q15651 High mobility group nucleosome-binding domain-containing protein 3 chr6 Not Cancer Driver No 1 hippie 14 99 14 14 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 Not Cancer Driver No 1 hippie 70 290 58 58 4
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 Not Cancer Driver No 1 hippie 39 206 19 19 0
HORMAD2 HORMAD2 Q8N7B1 HORMA domain-containing protein 2 chr22 Not Cancer Driver No 1 hippie, biogrid 28 29 3 3 0
HPSE HPSE Q9Y251 Heparanase chr4 Not Cancer Driver No 1 intact, hippie 90 16 2 2 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 Not Cancer Driver No 1 hippie 59 335 37 37 0
HSF2 HSF2 Q03933 Heat shock factor protein 2 chr6 Not Cancer Driver No 1 hippie 64 292 37 37 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 2 intact, hippie 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 hippie 100 254 43 43 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 3 hippie, biogrid 24 200 13 13 0
HSPA1B HSPA1B P0DMV9 Heat shock 70 kDa protein 1B chr6 Not Cancer Driver No 1 biogrid 15 200 5 5 0
HSPA1L HSPA1L P34931 Heat shock 70 kDa protein 1-like chr6 Not Cancer Driver No 2 hippie, biogrid 119 141 28 28 0
HSPA2_ENST00000247207 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 Not Cancer Driver No 4 hippie, biogrid 93 286 38 38 0
HSPA4 HSPA4 P34932 Heat shock 70 kDa protein 4 chr5 Not Cancer Driver No 1 hippie 80 351 24 24 0
HSPA4L_ENST00000508776 HSPA4L O95757 Heat shock 70 kDa protein 4L chr4 Not Cancer Driver No 1 hippie 105 266 28 28 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 hippie 73 282 35 35 0
HSPA6 HSPA6 P17066 Heat shock 70 kDa protein 6 chr1 Not Cancer Driver No 1 hippie 112 235 27 27 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 3 intact, hippie, biogrid 149 251 52 52 0
HSPA9 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 1 hippie 67 283 26 26 2
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 hippie 10 118 8 8 20
HSPBP1 HSPBP1 Q9NZL4 Hsp70-binding protein 1 chr19 Not Cancer Driver No 2 hippie, biogrid 29 130 7 7 0
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 hippie 61 82 6 6 2
HTT HTT P42858 Huntingtin chr4 Not Cancer Driver No 1 hippie 336 666 69 69 2
HUS1B HUS1B Q8NHY5 Checkpoint protein HUS1B chr6 Not Cancer Driver No 1 hippie 50 10 1 1 0
IFITM3 IFITM3 Q01628 Interferon-induced transmembrane protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 69 18 5 5 0
IGF2R IGF2R P11717 Cation-independent mannose-6-phosphate receptor chr6 Not Cancer Driver No 1 hippie 318 255 20 20 0
IKZF1 IKZF1 Q13422 DNA-binding protein Ikaros chr7 Census, Compendium Yes 1 hippie 143 326 92 92 5
ILK_ENST00000299421 ILK Q13418 Integrin-linked protein kinase chr11 Not Cancer Driver No 2 hippie, biogrid 45 71 9 9 0
INF2 INF2 Q27J81 Inverted formin-2 chr14 Not Cancer Driver No 1 hippie, biogrid 120 635 49 49 30
INO80_ENST00000401393 INO80 Q9ULG1 Chromatin-remodeling ATPase INO80 chr15 Compendium Yes 1 hippie 173 682 76 76 0
INSR INSR P06213 Insulin receptor chr19 Not Cancer Driver No 1 hippie 190 280 57 57 64
IRAK1 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX Compendium Yes 2 hippie, biogrid 71 337 39 39 0
IREB2 IREB2 P48200 Iron-responsive element-binding protein 2 chr15 Not Cancer Driver No 1 hippie 126 107 13 13 0
IRF1 IRF1 P10914 Interferon regulatory factor 1 chr5 Compendium Yes 1 hippie 49 228 31 31 2
IRS4 IRS4 O14654 Insulin receptor substrate 4 chrX Census, Compendium Yes 1 hippie 297 798 203 203 0
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 Census, Compendium Yes 2 hippie, biogrid 167 63 10 10 7
JOSD1 JOSD1 Q15040 Josephin-1 chr22 Not Cancer Driver No 1 hippie 18 23 1 1 0
JOSD2_ENST00000601423 JOSD2 Q8TAC2 Josephin-2 chr19 Not Cancer Driver No 1 hippie 24 21 4 4 0
KATNA1 KATNA1 O75449 Katanin p60 ATPase-containing subunit A1 chr6 Not Cancer Driver No 1 hippie 66 199 30 30 0
KCNA5 KCNA5 P22460 Potassium voltage-gated channel subfamily A member 5 chr12 Not Cancer Driver No 1 hippie 213 218 53 53 0
KCNC4 KCNC4 Q03721 Potassium voltage-gated channel subfamily C member 4 chr1 Not Cancer Driver No 1 hippie, biogrid 105 244 38 38 0
KCND2 KCND2 Q9NZV8 Potassium voltage-gated channel subfamily D member 2 chr7 Not Cancer Driver No 1 hippie, biogrid 220 195 62 62 0
KCNH2 KCNH2 Q12809 Potassium voltage-gated channel subfamily H member 2 chr7 Not Cancer Driver No 1 hippie 189 466 50 50 117
KCNMA1 KCNMA1 Q12791 Calcium-activated potassium channel subunit alpha-1 chr10 Not Cancer Driver No 1 intact 222 225 39 39 5
KCNQ4_ENST00000347132 KCNQ4 P56696 Potassium voltage-gated channel subfamily KQT member 4 chr1 Not Cancer Driver No 1 hippie 83 267 31 31 7
KDF1 KDF1 Q8NAX2 Keratinocyte differentiation factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 61 277 50 50 0
KDM4B KDM4B O94953 Lysine-specific demethylase 4B chr19 Not Cancer Driver No 1 hippie, biogrid 133 429 49 49 3
KHDC1 KHDC1 Q4VXA5 KH homology domain-containing protein 1 chr6 Not Cancer Driver No 1 hippie, biogrid 38 23 2 2 0
KHDRBS1 KHDRBS1 Q07666 KH domain-containing, RNA-binding, signal transduction-associated protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 53 362 43 43 0
KIAA0100 KIAA0100 Q14667 Protein KIAA0100 chr17 Not Cancer Driver No 1 hippie, biogrid 274 364 46 46 0
KIAA0753 KIAA0753 Q2KHM9 Protein moonraker chr17 Not Cancer Driver No 1 hippie 109 647 82 82 0
KLHDC2 KLHDC2 Q9Y2U9 Kelch domain-containing protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 39 42 2 2 0
KLHL29 KLHL29 Q96CT2 Kelch-like protein 29 chr2 Not Cancer Driver No 1 hippie 38 347 20 20 0
KLHL33 KLHL33 A6NCF5 Kelch-like protein 33 chr14 Not Cancer Driver No 1 hippie, biogrid 28 45 5 5 0
KLHL34 KLHL34 Q8N239 Kelch-like protein 34 chrX Not Cancer Driver No 2 hippie, biogrid 103 77 12 12 0
KLHL38 KLHL38 Q2WGJ6 Kelch-like protein 38 chr8 Not Cancer Driver No 1 hippie 114 3 2 2 0
KMT2E KMT2E Q8IZD2 Inactive histone-lysine N-methyltransferase 2E chr7 Not Cancer Driver No 1 hippie 233 1613 198 198 4
KSR2_ENST00000339824 KSR2 Q6VAB6 Kinase suppressor of Ras 2 chr12 Not Cancer Driver No 1 hippie 231 434 120 120 0
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 13 96 7 7 0
LATS2 LATS2 Q9NRM7 Serine/threonine-protein kinase LATS2 chr13 Census, Compendium Yes 1 hippie, biogrid 178 687 116 116 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie, biogrid 86 94 13 13 1
LDHA_ENST00000422447 LDHA P00338 L-lactate dehydrogenase A chain chr11 Not Cancer Driver No 1 hippie 40 9 0 0 0
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 Census Yes 1 hippie 64 370 57 57 0
LGALS1 LGALS1 P09382 Galectin-1 chr22 Not Cancer Driver No 1 hippie 16 0 0 0 0
LIMS1_ENST00000393310 LIMS1 P48059 LIM and senescent cell antigen-like-containing domain protein 1 chr2 Not Cancer Driver No 1 hippie 34 0 0 0 0
LLGL1 LLGL1 Q15334 Lethal(2) giant larvae protein homolog 1 chr17 Not Cancer Driver No 1 hippie 101 265 12 12 0
LLGL2 LLGL2 Q6P1M3 LLGL scribble cell polarity complex component 2 chr17 Not Cancer Driver No 1 hippie 120 266 26 26 0
LMAN1 LMAN1 P49257 Protein ERGIC-53 chr18 Not Cancer Driver No 1 hippie, biogrid 63 222 25 25 1
LMNA LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie 68 544 49 49 131
LOXL4 LOXL4 Q96JB6 Lysyl oxidase homolog 4 chr10 Not Cancer Driver No 1 hippie, biogrid 95 122 11 11 0
LRP1 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 Not Cancer Driver No 1 hippie 664 317 52 52 1
LRRK1 LRRK1 Q38SD2 Leucine-rich repeat serine/threonine-protein kinase 1 chr15 Not Cancer Driver No 1 hippie 289 261 33 33 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 Census, Compendium Yes 1 hippie 75 139 12 12 1
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 Compendium Yes 1 hippie, biogrid 89 144 20 20 0
MAP3K11 MAP3K11 Q16584 Mitogen-activated protein kinase kinase kinase 11 chr11 Not Cancer Driver No 1 hippie 97 466 54 54 0
MAP3K14 MAP3K14 Q99558 Mitogen-activated protein kinase kinase kinase 14 chr17 Not Cancer Driver No 1 hippie 94 543 52 52 0
MAP3K21 MAP3K21 Q5TCX8 Mitogen-activated protein kinase kinase kinase 21 chr1 Not Cancer Driver No 1 hippie 191 658 112 112 0
MAP3K2_ENST00000344908 MAP3K2 Q9Y2U5 Mitogen-activated protein kinase kinase kinase 2 chr2 Not Cancer Driver No 1 hippie 75 313 47 47 0
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 Not Cancer Driver No 1 hippie 74 355 44 44 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 Not Cancer Driver No 1 hippie 197 242 29 29 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 Not Cancer Driver No 1 hippie 104 333 66 66 6
MAP3K9_ENST00000554752 MAP3K9 P80192 Mitogen-activated protein kinase kinase kinase 9 chr14 Not Cancer Driver No 1 hippie, biogrid 167 684 104 104 0
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie 38 49 5 5 0
MAPK4 MAPK4 P31152 Mitogen-activated protein kinase 4 chr18 Not Cancer Driver No 1 hippie, biogrid 111 222 42 42 0
MAPK6 MAPK6 Q16659 Mitogen-activated protein kinase 6 chr15 Not Cancer Driver No 1 hippie 79 165 20 20 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 2 intact, hippie 128 750 126 126 18
MARCKS MARCKS P29966 Myristoylated alanine-rich C-kinase substrate chr6 Not Cancer Driver No 1 hippie, biogrid 14 328 14 14 0
MAST1 MAST1 Q9Y2H9 Microtubule-associated serine/threonine-protein kinase 1 chr19 Not Cancer Driver No 1 hippie 204 1078 119 119 1
MCF2_ENST00000370576 MCF2 P10911 Proto-oncogene DBL chrX Not Cancer Driver No 1 hippie 218 124 33 33 0
MCM5 MCM5 P33992 DNA replication licensing factor MCM5 chr22 Not Cancer Driver No 1 hippie 88 109 20 20 1
MEN1 MEN1 O00255 Menin chr11 Census, Compendium Yes 1 hippie 73 228 15 15 90
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 Not Cancer Driver No 1 hippie 74 274 29 29 0
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 Census, Compendium Yes 1 hippie 226 62 15 15 19
MEX3C MEX3C Q5U5Q3 RNA-binding E3 ubiquitin-protein ligase MEX3C chr18 Not Cancer Driver No 1 hippie 54 475 32 32 0
MFHAS1 MFHAS1 Q9Y4C4 Malignant fibrous histiocytoma-amplified sequence 1 chr8 Not Cancer Driver No 1 hippie 95 98 9 9 0
MIF MIF P14174 Macrophage migration inhibitory factor chr22 Not Cancer Driver No 1 hippie 4 0 0 0 0
MITF_ENST00000448226 MITF O75030 Microphthalmia-associated transcription factor chr3 Census Yes 1 hippie 80 408 69 69 7
MKKS MKKS Q9NPJ1 McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin chr20 Not Cancer Driver No 1 hippie 56 6 1 1 22
MLF1_ENST00000355893 MLF1 P58340 Myeloid leukemia factor 1 chr3 Census Yes 2 hippie, biogrid 40 243 37 37 0
MLF2_ENST00000542154 MLF2 Q15773 Myeloid leukemia factor 2 chr12 Not Cancer Driver No 2 hippie, biogrid 37 187 32 32 0
MLST8_ENST00000397124 MLST8 Q9BVC4 Target of rapamycin complex subunit LST8 chr16 Not Cancer Driver No 1 hippie, biogrid 37 45 3 3 0
MOS MOS P00540 Proto-oncogene serine/threonine-protein kinase mos chr8 Not Cancer Driver No 2 hippie, biogrid 94 16 4 4 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MPO MPO P05164 Myeloperoxidase chr17 Not Cancer Driver No 1 hippie 149 52 12 12 3
MPP1 MPP1 Q00013 55 kDa erythrocyte membrane protein chrX Not Cancer Driver No 1 hippie, biogrid 79 194 33 33 0
MST1R MST1R Q04912 Macrophage-stimulating protein receptor chr3 Not Cancer Driver No 1 hippie 178 182 27 27 1
MTCH1 MTCH1 Q9NZJ7 Mitochondrial carrier homolog 1 chr6 Not Cancer Driver No 1 hippie, biogrid 31 102 2 2 0
MTCH2 MTCH2 Q9Y6C9 Mitochondrial carrier homolog 2 chr11 Not Cancer Driver No 2 hippie, biogrid 45 11 0 0 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYLK MYLK Q15746 Myosin light chain kinase, smooth muscle chr3 Not Cancer Driver No 1 hippie, biogrid 343 957 184 184 3
MYO3B MYO3B Q8WXR4 Myosin-IIIb chr2 Not Cancer Driver No 1 hippie, biogrid 242 308 58 58 0
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 Not Cancer Driver No 1 hippie 284 853 263 263 0
MZF1 MZF1 P28698 Myeloid zinc finger 1 chr19 Not Cancer Driver No 1 hippie 77 468 49 49 0
NADSYN1 NADSYN1 Q6IA69 Glutamine-dependent NAD(+) synthetase chr11 Not Cancer Driver No 2 hippie, biogrid 82 27 8 8 3
NAT16_ENST00000455377 NAT16 Q8N8M0 Probable N-acetyltransferase 16 chr7 Not Cancer Driver No 1 hippie, biogrid 33 69 8 8 0
NCAM1_ENST00000316851 NCAM1 P13591 Neural cell adhesion molecule 1 chr11 Not Cancer Driver No 1 hippie 207 290 70 70 0
NEK4 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 Not Cancer Driver No 1 hippie 78 492 49 49 0
NEK8 NEK8 Q86SG6 Serine/threonine-protein kinase Nek8 chr17 Not Cancer Driver No 1 hippie, biogrid 102 167 40 40 3
NF2 NF2 P35240 Merlin chr22 Census, Compendium Yes 1 hippie 69 252 26 26 16
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 Not Cancer Driver No 1 hippie 104 344 38 38 0
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 Not Cancer Driver No 1 hippie 57 172 25 25 0
NHLRC1 NHLRC1 Q6VVB1 E3 ubiquitin-protein ligase NHLRC1 chr6 Not Cancer Driver No 1 hippie 66 18 3 3 22
NLRP12_ENST00000324134 NLRP12 P59046 NACHT, LRR and PYD domains-containing protein 12 chr19 Not Cancer Driver No 1 hippie 310 116 43 43 0
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 Not Cancer Driver No 1 hippie 339 64 33 33 37
NMRAL1 NMRAL1 Q9HBL8 NmrA-like family domain-containing protein 1 chr16 Not Cancer Driver No 1 hippie 39 14 3 3 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 Not Cancer Driver No 1 hippie, biogrid 169 40 4 4 15
NOS1_ENST00000317775 NOS1 P29475 Nitric oxide synthase, brain chr12 Not Cancer Driver No 1 hippie 405 342 99 99 0
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 Not Cancer Driver No 1 hippie 207 201 33 33 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 Census, Compendium Yes 1 hippie 363 686 87 87 3
NOX5 NOX5 Q96PH1 NADPH oxidase 5 chr15 Not Cancer Driver No 1 hippie 118 95 9 9 0
NOXO1 NOXO1 Q8NFA2 NADPH oxidase organizer 1 chr16 Not Cancer Driver No 1 hippie, biogrid 29 182 9 9 0
NPAS1_ENST00000449844 NPAS1 Q99742 Neuronal PAS domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 53 309 23 23 0
NPRL2 NPRL2 Q8WTW4 GATOR complex protein NPRL2 chr3 Compendium Yes 1 hippie 37 10 3 3 1
NQO1 NQO1 P15559 NAD(P)H dehydrogenase [quinone] 1 chr16 Not Cancer Driver No 1 hippie 21 10 1 1 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
NR3C2_ENST00000344721 NR3C2 P08235 Mineralocorticoid receptor chr4 Not Cancer Driver No 1 hippie 168 484 88 88 14
NUBP2 NUBP2 Q9Y5Y2 Cytosolic Fe-S cluster assembly factor NUBP2 chr16 Not Cancer Driver No 1 hippie, biogrid 38 14 0 0 0
NUDCD2 NUDCD2 Q8WVJ2 NudC domain-containing protein 2 chr5 Not Cancer Driver No 1 hippie, biogrid 12 39 6 6 0
NUP155 NUP155 O75694 Nuclear pore complex protein Nup155 chr5 Not Cancer Driver No 1 hippie, biogrid 154 221 19 19 1
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
OLA1 OLA1 Q9NTK5 Obg-like ATPase 1 chr2 Not Cancer Driver No 1 hippie 41 40 5 5 0
OLFM3 OLFM3 Q96PB7 Noelin-3 chr1 Not Cancer Driver No 1 hippie 148 44 17 17 0
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 hippie 31 33 2 2 0
OTUD3 OTUD3 Q5T2D3 OTU domain-containing protein 3 chr1 Not Cancer Driver No 1 hippie 43 280 25 25 0
P4HA2_ENST00000379104 P4HA2 O15460 Prolyl 4-hydroxylase subunit alpha-2 chr5 Not Cancer Driver No 1 hippie, biogrid 66 82 12 12 2
PA2G4 PA2G4 Q9UQ80 Proliferation-associated protein 2G4 chr12 Not Cancer Driver No 1 hippie 45 128 18 18 0
PABPN1 PABPN1 Q86U42 Polyadenylate-binding protein 2 chr14 Not Cancer Driver No 1 hippie 27 241 18 18 0
PACRG PACRG Q96M98 Parkin coregulated gene protein chr6 Not Cancer Driver No 1 hippie 66 45 6 6 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 Not Cancer Driver No 1 hippie 42 82 11 11 7
PAICS_ENST00000512576 PAICS P22234 Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase chr4 Not Cancer Driver No 1 hippie, biogrid 23 35 3 3 0
PANK2 PANK2 Q9BZ23 Pantothenate kinase 2, mitochondrial chr20 Not Cancer Driver No 1 hippie 46 206 14 14 30
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 Not Cancer Driver No 1 hippie 11 30 0 0 5
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 Not Cancer Driver No 2 hippie, biogrid 119 320 34 34 0
PARP10_ENST00000313028 PARP10 Q53GL7 Protein mono-ADP-ribosyltransferase PARP10 chr8 Not Cancer Driver No 1 hippie 122 552 68 68 0
PCBP1 PCBP1 Q15365 Poly(rC)-binding protein 1 chr2 Census, Compendium Yes 1 hippie 65 166 24 24 0
PCSK9 PCSK9 Q8NBP7 Proprotein convertase subtilisin/kexin type 9 chr1 Not Cancer Driver No 1 hippie 86 148 27 27 9
PDK3_ENST00000379162 PDK3 Q15120 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 61 28 6 6 1
PDLIM5_ENST00000317968 PDLIM5 Q96HC4 PDZ and LIM domain protein 5 chr4 Not Cancer Driver No 1 hippie 89 372 57 57 0
PELI3 PELI3 Q8N2H9 E3 ubiquitin-protein ligase pellino homolog 3 chr11 Not Cancer Driver No 1 hippie, biogrid 48 216 25 25 0
PEX14 PEX14 O75381 Peroxisomal membrane protein PEX14 chr1 Not Cancer Driver No 1 hippie, biogrid 38 266 28 28 0
PEX7 PEX7 O00628 Peroxisomal targeting signal 2 receptor chr6 Not Cancer Driver No 1 hippie 32 0 0 0 2
PFN1 PFN1 P07737 Profilin-1 chr17 Not Cancer Driver No 1 hippie 16 7 1 1 3
PGR PGR P06401 Progesterone receptor chr11 Not Cancer Driver No 1 hippie 161 480 55 55 0
PHKG2 PHKG2 P15735 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform chr16 Not Cancer Driver No 1 hippie 48 50 6 6 4
PHLPP1 PHLPP1 O60346 PH domain leucine-rich repeat-containing protein phosphatase 1 chr18 Not Cancer Driver No 1 hippie 134 744 29 29 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 1 hippie 154 268 61 61 2
PIK3R6_ENST00000614407 PIK3R6 Q5UE93 Phosphoinositide 3-kinase regulatory subunit 6 chr17 Not Cancer Driver No 1 hippie, biogrid 100 156 26 26 0
PKDCC PKDCC Q504Y2 Extracellular tyrosine-protein kinase PKDCC chr2 Not Cancer Driver No 1 hippie, biogrid 36 124 0 0 0
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie 78 58 13 13 0
PKN3 PKN3 Q6P5Z2 Serine/threonine-protein kinase N3 chr9 Not Cancer Driver No 1 hippie, biogrid 99 392 49 49 0
PLD2 PLD2 O14939 Phospholipase D2 chr17 Not Cancer Driver No 2 hippie, biogrid 107 97 8 8 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLEKHA7 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 1 hippie 152 919 121 121 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 Not Cancer Driver No 1 hippie 87 119 13 13 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 Not Cancer Driver No 1 hippie 2 23 1 1 0
PNPLA5 PNPLA5 Q7Z6Z6 Patatin-like phospholipase domain-containing protein 5 chr22 Not Cancer Driver No 1 hippie, biogrid 78 33 8 8 0
POLB POLB P06746 DNA polymerase beta chr8 Not Cancer Driver No 1 hippie 43 87 11 11 0
POLR2C POLR2C P19387 DNA-directed RNA polymerase II subunit RPB3 chr16 Not Cancer Driver No 1 hippie, biogrid 34 108 11 11 0
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 Census, Compendium Yes 1 hippie 113 31 6 6 9
POU5F1 POU5F1 Q01860 POU domain, class 5, transcription factor 1 chr6 Census Yes 1 hippie 36 186 12 12 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 Census Yes 1 hippie 72 44 4 4 3
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 1 hippie 179 0 0 0 4
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 Compendium Yes 1 hippie 85 140 27 27 7
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 1 hippie 53 24 0 0 2
PRKACG PRKACG P22612 cAMP-dependent protein kinase catalytic subunit gamma chr9 Not Cancer Driver No 1 hippie, biogrid 74 23 7 7 1
PRKAG3_ENST00000529249 PRKAG3 Q9UGI9 5'-AMP-activated protein kinase subunit gamma-3 chr2 Not Cancer Driver No 1 hippie, biogrid 74 144 25 25 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 Not Cancer Driver No 1 hippie 70 116 11 11 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 110 78 15 15 31
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 Not Cancer Driver No 1 hippie 50 18 1 1 0
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 Not Cancer Driver No 1 hippie 83 72 6 6 0
PRPF19 PRPF19 Q9UMS4 Pre-mRNA-processing factor 19 chr11 Not Cancer Driver No 1 hippie, biogrid 71 109 16 16 0
PRPF8 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 2 hippie, biogrid 255 225 26 26 8
PRPH PRPH P41219 Peripherin chr12 Not Cancer Driver No 1 hippie, biogrid 37 239 20 20 0
PSKH2 PSKH2 Q96QS6 Serine/threonine-protein kinase H2 chr8 Not Cancer Driver No 1 hippie, biogrid 86 87 19 19 0
PSMA3 PSMA3 P25788 Proteasome subunit alpha type-3 chr14 Not Cancer Driver No 1 hippie 27 30 5 5 0
PSMA4_ENST00000559082 PSMA4 P25789 Proteasome subunit alpha type-4 chr15 Not Cancer Driver No 1 hippie 29 28 9 9 0
PSMB2 PSMB2 P49721 Proteasome subunit beta type-2 chr1 Not Cancer Driver No 1 hippie 24 0 0 0 0
PSMC2_ENST00000292644 PSMC2 P35998 26S proteasome regulatory subunit 7 chr7 Not Cancer Driver No 1 hippie 63 120 13 13 0
PSMD1 PSMD1 Q99460 26S proteasome non-ATPase regulatory subunit 1 chr2 Not Cancer Driver No 1 hippie 110 201 19 19 0
PSMD14 PSMD14 O00487 26S proteasome non-ATPase regulatory subunit 14 chr2 Not Cancer Driver No 1 hippie, biogrid 23 67 6 6 0
PSMD2 PSMD2 Q13200 26S proteasome non-ATPase regulatory subunit 2 chr3 Not Cancer Driver No 1 hippie 100 135 14 14 0
PSMD4_ENST00000368884 PSMD4 P55036 26S proteasome non-ATPase regulatory subunit 4 chr1 Not Cancer Driver No 2 hippie, biogrid 43 243 25 25 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 Census, Compendium Yes 1 hippie 505 76 4 4 41
PTGES3_ENST00000262033 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 Not Cancer Driver No 1 hippie 11 52 3 3 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 Not Cancer Driver No 1 hippie 134 425 55 55 0
PTPN18 PTPN18 Q99952 Tyrosine-protein phosphatase non-receptor type 18 chr2 Not Cancer Driver No 1 hippie, biogrid 51 138 8 8 0
PTPRR PTPRR Q15256 Receptor-type tyrosine-protein phosphatase R chr12 Not Cancer Driver No 1 hippie 172 73 28 28 0
PXMP2 PXMP2 Q9NR77 Peroxisomal membrane protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 15 0 0 0 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 hippie 27 11 0 0 4
RAD23B RAD23B P54727 UV excision repair protein RAD23 homolog B chr9 Not Cancer Driver No 1 hippie, biogrid 54 324 41 41 0
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 Census, Compendium Yes 1 hippie 89 169 38 38 22
RBFOX3 RBFOX3 A6NFN3 RNA binding protein fox-1 homolog 3 chr17 Not Cancer Driver No 1 hippie 13 172 7 7 0
RCN2_ENST00000394885 RCN2 Q14257 Reticulocalbin-2 chr15 Not Cancer Driver No 1 hippie 35 125 11 11 0
REC8_ENST00000611366 REC8 O95072 Meiotic recombination protein REC8 homolog chr14 Not Cancer Driver No 2 hippie, biogrid 60 244 26 26 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RELA RELA Q04206 Transcription factor p65 chr11 Compendium Yes 1 hippie 75 400 48 48 0
RFX1 RFX1 P22670 MHC class II regulatory factor RFX1 chr19 Not Cancer Driver No 1 hippie 114 536 66 66 0
RGS17 RGS17 Q9UGC6 Regulator of G-protein signaling 17 chr6 Not Cancer Driver No 1 hippie 45 48 11 11 0
RHBDF2 RHBDF2 Q6PJF5 Inactive rhomboid protein 2 chr17 Not Cancer Driver No 1 hippie 93 284 36 36 2
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RIN3 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 hippie 137 417 61 61 0
RIPK4_ENST00000352483 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 hippie 119 232 34 34 3
RMND5A RMND5A Q9H871 E3 ubiquitin-protein transferase RMND5A chr2 Not Cancer Driver No 1 hippie 46 0 0 0 0
RPS6KB2 RPS6KB2 Q9UBS0 Ribosomal protein S6 kinase beta-2 chr11 Not Cancer Driver No 1 hippie 54 194 16 16 0
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 Census, Compendium Yes 1 hippie 81 360 58 58 2
RUNX2_ENST00000647337 RUNX2 Q13950 Runt-related transcription factor 2 chr6 Not Cancer Driver No 1 hippie 83 447 73 73 47
RUSC1 RUSC1 Q9BVN2 AP-4 complex accessory subunit RUSC1 chr1 Not Cancer Driver No 1 hippie 99 640 69 69 0
S100A2_ENST00000368709 S100A2 P29034 Protein S100-A2 chr1 Not Cancer Driver No 1 hippie 16 6 2 2 0
S100A6_ENST00000496817 S100A6 P06703 Protein S100-A6 chr1 Not Cancer Driver No 1 hippie 5 4 0 0 0
S100P S100P P25815 Protein S100-P chr4 Not Cancer Driver No 1 hippie 7 3 1 1 0
SEC23A SEC23A Q15436 Protein transport protein Sec23A chr14 Not Cancer Driver No 1 hippie, biogrid 100 73 8 8 1
SEC24A SEC24A O95486 Protein transport protein Sec24A chr5 Not Cancer Driver No 1 hippie, biogrid 113 407 49 49 0
SEM1_ENST00000356686 SEM1 Q6ZVN7 Putative protein SEM1, isoform 2 chr7 Not Cancer Driver No 1 hippie 2 52 1 1 0
SENP3_ENST00000429205 SENP3 Q9H4L4 Sentrin-specific protease 3 chr17 Not Cancer Driver No 1 hippie 53 288 30 30 0
SERPINA3_ENST00000393080 SERPINA3 P01011 Alpha-1-antichymotrypsin chr14 Not Cancer Driver No 1 hippie 117 18 10 10 0
SGK1_ENST00000237305 SGK1 O00141 Serine/threonine-protein kinase Sgk1 chr6 Census, Compendium Yes 1 hippie 58 86 16 16 0
SH3BGRL SH3BGRL O75368 SH3 domain-binding glutamic acid-rich-like protein chrX Not Cancer Driver No 1 hippie, biogrid 23 51 8 8 0
SHARPIN SHARPIN Q9H0F6 Sharpin chr8 Not Cancer Driver No 1 hippie 34 237 16 16 0
SIK3 SIK3 Q9Y2K2 Serine/threonine-protein kinase SIK3 chr11 Not Cancer Driver No 1 hippie, biogrid 143 964 107 107 1
SIM2 SIM2 Q14190 Single-minded homolog 2 chr21 Not Cancer Driver No 1 hippie 62 262 12 12 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 Not Cancer Driver No 1 hippie 33 164 12 12 0
SKA3 SKA3 Q8IX90 Spindle and kinetochore-associated protein 3 chr13 Not Cancer Driver No 1 hippie 56 230 32 32 0
SKP2 SKP2 Q13309 S-phase kinase-associated protein 2 chr5 Not Cancer Driver No 1 hippie 52 52 6 6 0
SLC12A3_ENST00000563236 SLC12A3 P55017 Solute carrier family 12 member 3 chr16 Not Cancer Driver No 1 hippie 146 124 16 16 117
SLC27A3_ENST00000271857 SLC27A3 X6R3N0 Solute carrier family 27 (Fatty acid transporter), member 3, isoform CRA_d chr1 Not Cancer Driver No 1 hippie, biogrid 80 171 16 16 0
SLC6A4_ENST00000401766 SLC6A4 P31645 Sodium-dependent serotonin transporter chr17 Not Cancer Driver No 1 hippie 101 73 12 12 0
SMAD1 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 Not Cancer Driver No 1 hippie 54 161 22 22 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 Census, Compendium Yes 1 hippie 79 137 12 12 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 Census, Compendium Yes 1 hippie 97 111 19 19 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 Census, Compendium Yes 1 hippie 198 195 17 17 8
SMAD5_ENST00000509297 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 Not Cancer Driver No 1 hippie 44 172 11 11 0
SMARCD2 SMARCD2 Q92925 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 chr17 Not Cancer Driver No 1 hippie 58 251 26 26 0
SMG5 SMG5 Q9UPR3 Nonsense-mediated mRNA decay factor SMG5 chr1 Not Cancer Driver No 1 hippie 132 295 51 51 0
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 Not Cancer Driver No 1 hippie 52 97 11 11 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 Not Cancer Driver No 1 hippie 52 52 9 9 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 Not Cancer Driver No 1 hippie 21 107 13 13 5
SNPH_ENST00000381873 SNPH O15079 Syntaphilin chr20 Not Cancer Driver No 1 hippie 79 406 71 71 0
SNRK SNRK Q9NRH2 SNF-related serine/threonine-protein kinase chr3 Not Cancer Driver No 1 hippie, biogrid 82 368 47 47 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 Not Cancer Driver No 1 hippie 16 93 9 9 79
SOHLH1_ENST00000298466 SOHLH1 Q5JUK2 Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 48 252 39 39 0
SP110_ENST00000358662 SP110 Q9HB58 Sp110 nuclear body protein chr2 Not Cancer Driver No 1 hippie, biogrid 92 368 54 54 0
SP7 SP7 Q8TDD2 Transcription factor Sp7 chr12 Not Cancer Driver No 1 hippie 63 332 44 44 0
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 Not Cancer Driver No 1 hippie 71 194 35 35 2
SPTLC1 SPTLC1 O15269 Serine palmitoyltransferase 1 chr9 Not Cancer Driver No 1 hippie 50 27 5 5 5
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie 54 267 32 32 30
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie 53 130 11 11 1
SRXN1 SRXN1 Q9BYN0 Sulfiredoxin-1 chr20 Not Cancer Driver No 1 hippie, biogrid 15 48 2 2 0
STAM STAM Q92783 Signal transducing adapter molecule 1 chr10 Not Cancer Driver No 1 hippie, biogrid 73 361 40 40 0
STIL_ENST00000360380 STIL Q15468 SCL-interrupting locus protein chr1 Census, Compendium Yes 1 hippie 147 735 85 85 1
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 Census, Compendium Yes 1 hippie 75 135 14 14 9
STMN2_ENST00000220876 STMN2 Q93045 Stathmin-2 chr8 Not Cancer Driver No 1 hippie 34 122 23 23 0
STRADB STRADB Q9C0K7 STE20-related kinase adapter protein beta chr2 Not Cancer Driver No 1 hippie, biogrid 53 84 7 7 0
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 Not Cancer Driver No 1 hippie 35 112 14 14 12
SULT1A1_ENST00000314752 SULT1A1 P50225 Sulfotransferase 1A1 chr16 Not Cancer Driver No 1 hippie, biogrid 69 14 3 3 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 Census Yes 1 hippie 54 305 53 53 0
TCAP TCAP O15273 Telethonin chr17 Not Cancer Driver No 2 hippie, biogrid 16 94 10 10 3
TCF7L2_ENST00000355995 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 Census, Compendium Yes 1 intact, hippie 122 516 93 93 0
TDRD3_ENST00000196169 TDRD3 Q9H7E2 Tudor domain-containing protein 3 chr13 Not Cancer Driver No 1 hippie 97 518 77 77 0
TEAD3_ENST00000639578 TEAD3 Q99594 Transcriptional enhancer factor TEF-5 chr6 Not Cancer Driver No 1 hippie 40 120 7 7 0
TERF1 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 Not Cancer Driver No 1 hippie 63 220 34 34 0
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 Not Cancer Driver No 1 hippie 33 361 20 20 0
TERT TERT O14746 Telomerase reverse transcriptase chr5 Census Yes 1 hippie 110 212 16 16 31
TET3 TET3 O43151 Methylcytosine dioxygenase TET3 chr2 Not Cancer Driver No 1 hippie 208 1272 152 152 6
TFDP3 TFDP3 Q5H9I0 Transcription factor Dp family member 3 chrX Not Cancer Driver No 1 hippie 84 186 42 42 0
TFEB_ENST00000403298 TFEB P19484 Transcription factor EB chr6 Census Yes 1 hippie 58 429 47 47 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 Not Cancer Driver No 1 hippie 41 41 4 4 10
TINF2 TINF2 Q9BSI4 TERF1-interacting nuclear factor 2 chr14 Not Cancer Driver No 1 hippie 38 190 17 17 4
TLE2_ENST00000262953 TLE2 Q04725 Transducin-like enhancer protein 2 chr19 Not Cancer Driver No 1 hippie, biogrid 78 283 29 29 0
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 Not Cancer Driver No 1 hippie 292 0 0 0 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 Not Cancer Driver No 1 hippie 141 35 3 3 0
TMEM185A TMEM185A Q8NFB2 Transmembrane protein 185A chrX Not Cancer Driver No 1 hippie, biogrid 29 19 0 0 0
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 43 316 36 36 0
TOMM40_ENST00000405636 TOMM40 O96008 Mitochondrial import receptor subunit TOM40 homolog chr19 Not Cancer Driver No 1 hippie 17 98 1 1 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 Census, Compendium Yes 1 hippie 229 398 143 143 28
TP73 TP73 O15350 Tumor protein p73 chr1 Not Cancer Driver No 1 hippie 82 443 55 55 0
TPD52_ENST00000379097 TPD52 P55327 Tumor protein D52 chr8 Not Cancer Driver No 1 hippie 25 177 19 19 0
TPM1_ENST00000403994 TPM1 P09493 Tropomyosin alpha-1 chain chr15 Not Cancer Driver No 1 hippie 33 234 29 29 8
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 Not Cancer Driver No 1 hippie 63 4 1 1 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 hippie 67 62 7 7 0
TRIM14 TRIM14 Q14142 Tripartite motif-containing protein 14 chr9 Not Cancer Driver No 1 hippie 36 93 7 7 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM68 TRIM68 Q6AZZ1 E3 ubiquitin-protein ligase TRIM68 chr11 Not Cancer Driver No 1 hippie, biogrid 74 37 7 7 0
TRIM6_ENST00000278302 TRIM6 Q9C030 Tripartite motif-containing protein 6 chr11 Not Cancer Driver No 1 hippie 86 47 15 15 0
TSSK1B TSSK1B Q9BXA7 Testis-specific serine/threonine-protein kinase 1 chr5 Not Cancer Driver No 1 hippie, biogrid 104 114 36 36 0
TUBA1A TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 hippie 59 52 11 11 8
TUBB3 TUBB3 Q13509 Tubulin beta-3 chain chr16 Not Cancer Driver No 1 hippie 67 53 10 10 12
TUBG1 TUBG1 P23258 Tubulin gamma-1 chain chr17 Not Cancer Driver No 1 hippie 51 44 10 10 3
TXLNG TXLNG Q9NUQ3 Gamma-taxilin chrX Not Cancer Driver No 2 hippie, biogrid 50 374 35 35 0
TXN2_ENST00000403313 TXN2 Q99757 Thioredoxin, mitochondrial chr22 Not Cancer Driver No 1 hippie 22 34 4 4 0
TYSND1 TYSND1 Q2T9J0 Peroxisomal leader peptide-processing protease chr10 Not Cancer Driver No 2 hippie, biogrid 40 135 12 12 0
UBA1 UBA1 P22314 Ubiquitin-like modifier-activating enzyme 1 chrX Not Cancer Driver No 1 hippie 117 165 22 22 6
UBE2D1 UBE2D1 P51668 Ubiquitin-conjugating enzyme E2 D1 chr10 Not Cancer Driver No 1 hippie 13 14 0 0 0
UBE2D2 UBE2D2 P62837 Ubiquitin-conjugating enzyme E2 D2 chr5 Compendium Yes 1 hippie 19 13 1 1 0
UBE2D3_ENST00000394801 UBE2D3 P61077 Ubiquitin-conjugating enzyme E2 D3 chr4 Not Cancer Driver No 1 hippie 21 13 4 4 0
UBE2D4 UBE2D4 Q9Y2X8 Ubiquitin-conjugating enzyme E2 D4 chr7 Not Cancer Driver No 1 hippie 13 21 1 1 0
UBE2E1 UBE2E1 P51965 Ubiquitin-conjugating enzyme E2 E1 chr3 Not Cancer Driver No 1 hippie 21 78 10 10 0
UBE2E2_ENST00000425792 UBE2E2 Q96LR5 Ubiquitin-conjugating enzyme E2 E2 chr3 Not Cancer Driver No 1 hippie 28 90 15 15 0
UBE2E3_ENST00000602710 UBE2E3 Q969T4 Ubiquitin-conjugating enzyme E2 E3 chr2 Not Cancer Driver No 1 hippie 34 97 14 14 0
UBE2L3_ENST00000342192 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 Not Cancer Driver No 1 hippie 19 32 4 4 0
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 hippie 30 32 6 6 0
UBE2N UBE2N P61088 Ubiquitin-conjugating enzyme E2 N chr12 Not Cancer Driver No 1 hippie 25 24 3 3 0
UBE2Q1 UBE2Q1 Q7Z7E8 Ubiquitin-conjugating enzyme E2 Q1 chr1 Not Cancer Driver No 1 hippie 45 173 16 16 0
UBE2V1_ENST00000371674 UBE2V1 Q13404 Ubiquitin-conjugating enzyme E2 variant 1 chr20 Not Cancer Driver No 1 biogrid 19 51 5 5 0
UBE2V2 UBE2V2 Q15819 Ubiquitin-conjugating enzyme E2 variant 2 chr8 Not Cancer Driver No 1 hippie, biogrid 22 76 12 12 0
UBE2W_ENST00000602593 UBE2W Q96B02 Ubiquitin-conjugating enzyme E2 W chr8 Not Cancer Driver No 1 hippie 19 26 5 5 0
UBE4B UBE4B O95155 Ubiquitin conjugation factor E4 B chr1 Not Cancer Driver No 1 hippie, biogrid 158 434 49 49 0
UBXN10 UBXN10 Q96LJ8 UBX domain-containing protein 10 chr1 Not Cancer Driver No 1 hippie 51 254 48 48 0
UBXN2A UBXN2A P68543 UBX domain-containing protein 2A chr2 Not Cancer Driver No 1 hippie 37 58 11 11 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
UNC45B UNC45B Q8IWX7 Protein unc-45 homolog B chr17 Not Cancer Driver No 1 hippie 167 55 6 6 3
URGCP URGCP Q8TCY9 Up-regulator of cell proliferation chr7 Not Cancer Driver No 1 hippie, biogrid 137 171 27 27 0
USP19_ENST00000398888 USP19 O94966 Ubiquitin carboxyl-terminal hydrolase 19 chr3 Not Cancer Driver No 1 hippie 161 539 68 68 0
USP49 USP49 Q70CQ1 Ubiquitin carboxyl-terminal hydrolase 49 chr6 Not Cancer Driver No 1 hippie 81 190 19 19 0
USP5 USP5 P45974 Ubiquitin carboxyl-terminal hydrolase 5 chr12 Not Cancer Driver No 1 hippie, biogrid 117 262 38 38 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 88 186 16 16 16
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 hippie 142 117 36 36 133
VIM_ENST00000224237 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 hippie 84 316 57 57 1
VPS13B VPS13B Q7Z7G8 Intermembrane lipid transfer protein VPS13B chr8 Not Cancer Driver No 1 hippie, biogrid 660 635 106 106 5
VPS29_ENST00000549578 VPS29 Q9UBQ0 Vacuolar protein sorting-associated protein 29 chr12 Not Cancer Driver No 1 hippie 24 0 0 0 0
VWA2 VWA2 Q5GFL6 von Willebrand factor A domain-containing protein 2 chr10 Not Cancer Driver No 1 hippie, biogrid 105 82 14 14 0
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 Not Cancer Driver No 1 hippie 105 203 10 10 39
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 hippie 79 108 9 9 3
XIAP_ENST00000434753 XIAP P98170 E3 ubiquitin-protein ligase XIAP chrX Not Cancer Driver No 1 hippie 89 55 6 6 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 51 489 49 49 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 hippie 32 41 3 3 0
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 1 hippie 29 41 6 6 0
ZBTB38_ENST00000441582 ZBTB38 Q8NAP3 Zinc finger and BTB domain-containing protein 38 chr3 Not Cancer Driver No 1 hippie 137 648 73 73 0