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SPSB1_ENST00000377399 ,SPSB1 ,Q96BD6
  • Uniprot Accession= Q96BD6
  • Ensembl Transcript= ENST00000377399.2
  • Uniprot Name= SPSB1
  • Name= SPRY domain-containing SOCS box protein 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 4
  • Number of Interaction partner in hippie: 49
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ADPRH ADPRH P54922 ADP-ribosylhydrolase ARH1 chr3 Not Cancer Driver No 1 hippie 54 30 3 3 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 Census, Compendium Yes 1 hippie 469 225 39 39 41
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 Census, Compendium Yes 1 hippie 338 106 14 14 1
ATRIP ATRIP Q8WXE1 ATR-interacting protein chr3 Not Cancer Driver No 1 hippie 76 383 32 32 0
CASP6 CASP6 P55212 Caspase-6 chr4 Not Cancer Driver No 1 hippie 28 24 4 4 0
CCK CCK P06307 Cholecystokinin chr3 Not Cancer Driver No 1 hippie 27 68 14 14 0
CRYAA CRYAA P02489 Alpha-crystallin A chain chr21 Not Cancer Driver No 1 hippie 34 42 11 11 10
CUL5 CUL5 Q93034 Cullin-5 chr11 Not Cancer Driver No 1 hippie 97 5 1 1 0
DDX4 DDX4 Q9NQI0 Probable ATP-dependent RNA helicase DDX4 chr5 Not Cancer Driver No 1 hippie 115 315 49 49 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
ELOB_ENST00000409906 ELOB Q15370 Elongin-B chr16 Not Cancer Driver No 1 hippie 13 69 10 10 0
ELOC ELOC Q15369 Elongin-C chr8 Not Cancer Driver No 1 hippie 22 25 5 5 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 Not Cancer Driver No 1 hippie 186 119 17 17 7
HIP1 HIP1 O00291 Huntingtin-interacting protein 1 chr7 Census, Compendium Yes 1 hippie 137 510 70 70 0
HMOX2_ENST00000406590 HMOX2 P30519 Heme oxygenase 2 chr16 Not Cancer Driver No 1 hippie 27 74 10 10 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 hippie 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 hippie 100 254 43 43 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 Not Cancer Driver No 1 hippie 67 291 28 28 3
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie 788 7 2 2 27
LAMP2_ENST00000200639 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX Not Cancer Driver No 1 hippie 43 55 7 7 1
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 Census, Compendium Yes 1 hippie 226 62 15 15 19
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 Not Cancer Driver No 1 hippie 207 201 33 33 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 Not Cancer Driver No 1 hippie 57 299 30 30 2
PAWR PAWR Q96IZ0 PRKC apoptosis WT1 regulator protein chr12 Not Cancer Driver No 1 hippie 35 327 33 33 0
PECAM1 PECAM1 P16284 Platelet endothelial cell adhesion molecule chr17 Not Cancer Driver No 1 hippie 2 153 2 2 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 110 78 15 15 31
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 Not Cancer Driver No 1 hippie 50 18 1 1 0
PRMT6 PRMT6 Q96LA8 Protein arginine N-methyltransferase 6 chr1 Not Cancer Driver No 1 hippie 43 71 7 7 0
PRNP PRNP P04156 Major prion protein chr20 Not Cancer Driver No 1 hippie 36 115 7 7 18
RAN_ENST00000392369 RAN P62826 GTP-binding nuclear protein Ran chr12 Not Cancer Driver No 1 hippie 20 14 1 1 0
RASA1 RASA1 P20936 Ras GTPase-activating protein 1 chr5 Compendium Yes 1 hippie 154 181 25 25 3
RELA RELA Q04206 Transcription factor p65 chr11 Compendium Yes 1 hippie 75 400 48 48 0
RNF11 RNF11 Q9Y3C5 RING finger protein 11 chr1 Not Cancer Driver No 1 hippie 17 76 7 7 0
RNF7 RNF7 Q9UBF6 RING-box protein 2 chr3 Not Cancer Driver No 1 hippie 17 0 0 0 0
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 Not Cancer Driver No 1 hippie 52 97 11 11 0
SPSB1_ENST00000377399 SPSB1 Q96BD6 SPRY domain-containing SOCS box protein 1 chr1 Not Cancer Driver No 1 hippie 35 26 3 3 0
SPSB4 SPSB4 Q96A44 SPRY domain-containing SOCS box protein 4 chr3 Not Cancer Driver No 1 hippie, biogrid 42 75 3 3 0
SUV39H1_ENST00000376687 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX Not Cancer Driver No 1 hippie 59 15 1 1 0
TARDBP TARDBP Q13148 TAR DNA-binding protein 43 chr1 Not Cancer Driver No 1 hippie 51 202 15 15 27
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 Census, Compendium Yes 1 hippie 106 60 16 16 25
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TP73 TP73 O15350 Tumor protein p73 chr1 Not Cancer Driver No 1 hippie 82 443 55 55 0
TRIM55 TRIM55 Q9BYV6 Tripartite motif-containing protein 55 chr8 Not Cancer Driver No 1 hippie, biogrid 134 276 78 78 0
TRIM63 TRIM63 Q969Q1 E3 ubiquitin-protein ligase TRIM63 chr1 Not Cancer Driver No 1 hippie, biogrid 47 71 13 13 0
TTC1 TTC1 Q99614 Tetratricopeptide repeat protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 28 211 21 21 0
UBE2K UBE2K P61086 Ubiquitin-conjugating enzyme E2 K chr4 Not Cancer Driver No 1 hippie 24 33 3 3 0
VIM_ENST00000224237 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 hippie 84 316 57 57 1
VWA5A VWA5A O00534 von Willebrand factor A domain-containing protein 5A chr11 Not Cancer Driver No 1 hippie 145 137 37 37 0