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SNX27 ,SNX27 ,Q96L92
  • Uniprot Accession= Q96L92
  • Ensembl Transcript= ENST00000458013.6
  • Uniprot Name= SNX27
  • Name= Sorting nexin-27
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 49
  • Number of Interaction partner in biogrid: 73
  • Number of Interaction partner in hippie: 119
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCC4_ENST00000376887 ABCC4 O15439 ATP-binding cassette sub-family C member 4 chr13 Not Cancer Driver No 1 hippie 174 97 6 6 0
AC006518.7 PRR4 A0A0A0MT31 Proline-rich protein 4 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 27 158 27 27 0
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX Not Cancer Driver No 2 intact, hippie 104 68 5 5 0
AHSG AHSG P02765 Alpha-2-HS-glycoprotein chr3 Not Cancer Driver No 2 intact, hippie, biogrid 74 131 41 41 0
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 Census Yes 1 intact, hippie 77 84 9 9 2
ALB ALB P02768 Albumin chr4 Compendium Yes 2 hippie, biogrid 162 6 0 0 3
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 Not Cancer Driver No 2 intact, hippie, biogrid 28 131 8 8 3
APOA2 APOA2 P02652 Apolipoprotein A-II chr1 Not Cancer Driver No 1 hippie, biogrid 13 0 0 0 0
APOA4 APOA4 P06727 Apolipoprotein A-IV chr11 Not Cancer Driver No 2 intact, hippie, biogrid 77 298 65 65 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ARHGEF7 ARHGEF7 Q14155 Rho guanine nucleotide exchange factor 7 chr13 Not Cancer Driver No 1 hippie 106 301 39 39 0
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX Not Cancer Driver No 1 hippie 228 171 46 46 52
BPIFA1_ENST00000375413 BPIFA1 Q9NP55 BPI fold-containing family A member 1 chr20 Not Cancer Driver No 2 hippie, biogrid 54 0 0 0 0
BPIFB1 BPIFB1 Q8TDL5 BPI fold-containing family B member 1 chr20 Not Cancer Driver No 2 hippie, biogrid 93 7 0 0 0
C3 C3 P01024 Complement C3 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 337 287 50 50 12
C3orf18_ENST00000426034 C3orf18 Q9UK00 Uncharacterized protein C3orf18 chr3 Not Cancer Driver No 1 hippie, biogrid 24 111 19 19 0
C4A C4A P0C0L4 Complement C4-A chr6 Not Cancer Driver No 2 intact, hippie, biogrid 43 309 6 6 0
C6orf58 LEG1 Q6P5S2 Protein LEG1 homolog chr6 Not Cancer Driver No 1 intact 71 24 5 5 0
CARTPT CARTPT Q16568 Cocaine- and amphetamine-regulated transcript protein chr5 Not Cancer Driver No 1 hippie, biogrid 18 0 0 0 0
CCL25 CCL25 O15444 C-C motif chemokine 25 chr19 Not Cancer Driver No 1 hippie, biogrid 20 26 6 6 0
CDK16_ENST00000357227 CDK16 Q00536 Cyclin-dependent kinase 16 chrX Not Cancer Driver No 2 hippie, biogrid 55 139 30 30 0
CDS1 CDS1 Q92903 Phosphatidate cytidylyltransferase 1 chr4 Not Cancer Driver No 2 intact, hippie, biogrid 73 66 9 9 0
CENPJ CENPJ Q9HC77 Centromere protein J chr13 Not Cancer Driver No 1 intact, hippie 176 1176 158 158 1
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 hippie 287 145 18 18 151
CHRDL1_ENST00000394797 CHRDL1 Q9BU40 Chordin-like protein 1 chrX Not Cancer Driver No 1 intact, hippie, biogrid 106 67 13 13 1
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie, biogrid 284 1017 160 160 3
CLU_ENST00000523500 CLU P10909 Clusterin chr8 Not Cancer Driver No 1 hippie, biogrid 69 156 27 27 0
COPS9_ENST00000607357 COPS9 Q8WXC6 COP9 signalosome complex subunit 9 chr2 Not Cancer Driver No 1 hippie 6 25 3 3 0
CP CP P00450 Ceruloplasmin chr3 Not Cancer Driver No 2 intact, hippie, biogrid 145 197 30 30 0
CST1 CST1 P01037 Cystatin-SN chr20 Not Cancer Driver No 1 intact, hippie, biogrid 33 0 0 0 0
CST4 CST4 P01036 Cystatin-S chr20 Not Cancer Driver No 2 hippie, biogrid 37 2 0 0 0
DGKZ_ENST00000456247 DGKZ Q13574 Diacylglycerol kinase zeta chr11 Not Cancer Driver No 1 hippie 87 410 42 42 0
DMBT1_ENST00000619379 DMBT1 Q9UGM3 Deleted in malignant brain tumors 1 protein chr10 Not Cancer Driver No 2 intact, hippie, biogrid 506 404 64 64 0
EEA1 EEA1 Q15075 Early endosome antigen 1 chr12 Not Cancer Driver No 2 intact, hippie 151 1168 126 126 0
EIF1AD EIF1AD Q8N9N8 Probable RNA-binding protein EIF1AD chr11 Not Cancer Driver No 1 hippie, biogrid 14 99 10 10 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
EVA1B EVA1B Q9NVM1 Protein eva-1 homolog B chr1 Not Cancer Driver No 1 hippie, biogrid 18 118 9 9 0
FAM124A_ENST00000322475 FAM124A Q86V42 Protein FAM124A chr13 Not Cancer Driver No 1 hippie, biogrid 69 357 39 39 0
FAM19A3_ENST00000361886 TAFA3 Q7Z5A8 Chemokine-like protein TAFA-3 chr1 Not Cancer Driver No 1 intact, hippie 17 6 0 0 0
FGA FGA P02671 Fibrinogen alpha chain chr4 Not Cancer Driver No 2 intact, hippie, biogrid 245 522 149 149 7
FGB FGB P02675 Fibrinogen beta chain chr4 Not Cancer Driver No 2 intact, hippie, biogrid 89 143 29 29 7
FGG FGG P02679 Fibrinogen gamma chain chr4 Not Cancer Driver No 2 intact, hippie, biogrid 81 53 8 8 8
FIG4 FIG4 Q92562 Polyphosphoinositide phosphatase chr6 Not Cancer Driver No 1 intact, hippie, biogrid 114 177 26 26 7
GC_ENST00000273951 GC P02774 Vitamin D-binding protein chr4 Not Cancer Driver No 1 hippie, biogrid 93 13 3 3 0
GPR156_ENST00000315843 GPR156 Q8NFN8 Probable G-protein coupled receptor 156 chr3 Not Cancer Driver No 2 hippie, biogrid 131 417 74 74 0
GREM2 GREM2 Q9H772 Gremlin-2 chr1 Not Cancer Driver No 1 hippie, biogrid 54 22 9 9 3
HLCS HLCS P50747 Biotin--protein ligase chr21 Not Cancer Driver No 1 intact, hippie 95 158 15 15 23
HP HP P00738 Haptoglobin chr16 Not Cancer Driver No 2 intact, hippie, biogrid 39 57 2 2 1
HPX HPX P02790 Hemopexin chr11 Not Cancer Driver No 2 intact, hippie, biogrid 60 53 8 8 0
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 61 82 6 6 2
IFITM3 IFITM3 Q01628 Interferon-induced transmembrane protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 69 18 5 5 0
IGLL5 IGLL5 B9A064 Immunoglobulin lambda-like polypeptide 5 chr22 Not Cancer Driver No 2 intact, hippie, biogrid 59 127 35 35 0
INSR INSR P06213 Insulin receptor chr19 Not Cancer Driver No 1 hippie 190 280 57 57 64
JCHAIN JCHAIN P01591 Immunoglobulin J chain chr4 Not Cancer Driver No 1 intact, hippie 37 9 3 3 0
KCNE3 KCNE3 Q9Y6H6 Potassium voltage-gated channel subfamily E member 3 chr11 Not Cancer Driver No 1 hippie, biogrid 28 24 2 2 0
KIDINS220 KIDINS220 Q9ULH0 Kinase D-interacting substrate of 220 kDa chr2 Not Cancer Driver No 1 hippie 245 683 113 113 0
KNG1 KNG1 P01042 Kininogen-1 chr3 Not Cancer Driver No 2 hippie, biogrid 130 294 66 66 1
LACRT LACRT Q9GZZ8 Extracellular glycoprotein lacritin chr12 Not Cancer Driver No 1 intact, hippie, biogrid 38 90 27 27 0
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 13 96 7 7 0
LCN1 LCN1 P31025 Lipocalin-1 chr9 Not Cancer Driver No 2 hippie, biogrid 31 69 17 17 0
LCN2_ENST00000277480 LCN2 P80188 Neutrophil gelatinase-associated lipocalin chr9 Not Cancer Driver No 2 intact, hippie, biogrid 29 4 3 3 0
LRFN4 LRFN4 Q6PJG9 Leucine-rich repeat and fibronectin type-III domain-containing protein 4 chr11 Not Cancer Driver No 1 intact, hippie 51 168 13 13 0
LRRC36 LRRC36 Q1X8D7 Leucine-rich repeat-containing protein 36 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 85 411 57 57 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
LTF LTF P02788 Lactotransferrin chr3 Not Cancer Driver No 2 intact, hippie, biogrid 131 21 4 4 0
LYZ LYZ P61626 Lysozyme C chr12 Not Cancer Driver No 1 intact, hippie, biogrid 26 0 0 0 2
MCC_ENST00000302475 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 1 intact, hippie 136 589 92 92 0
MRAP2 MRAP2 Q96G30 Melanocortin-2 receptor accessory protein 2 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 55 75 17 17 0
MRPL42 MRPL42 Q9Y6G3 39S ribosomal protein L42, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 18 52 5 5 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 Census Yes 1 hippie, biogrid 92 37 4 4 70
MTPN MTPN P58546 Myotrophin chr7 Not Cancer Driver No 1 hippie, biogrid 11 11 3 3 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
ORM1 ORM1 P02763 Alpha-1-acid glycoprotein 1 chr9 Not Cancer Driver No 2 hippie, biogrid 38 23 2 2 0
OTULIN OTULIN Q96BN8 Ubiquitin thioesterase otulin chr5 Not Cancer Driver No 1 hippie 47 97 5 5 2
PDCD2L PDCD2L Q9BRP1 Programmed cell death protein 2-like chr19 Not Cancer Driver No 1 hippie, biogrid 35 83 6 6 0
PHLPP1 PHLPP1 O60346 PH domain leucine-rich repeat-containing protein phosphatase 1 chr18 Not Cancer Driver No 1 intact, hippie, biogrid 134 744 29 29 0
PHLPP2 PHLPP2 Q6ZVD8 PH domain leucine-rich repeat-containing protein phosphatase 2 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 157 309 37 37 0
PIBF1 PIBF1 Q8WXW3 Progesterone-induced-blocking factor 1 chr13 Not Cancer Driver No 2 intact, hippie 83 419 45 45 2
PIGR PIGR P01833 Polymeric immunoglobulin receptor chr1 Not Cancer Driver No 2 hippie, biogrid 126 177 37 37 0
PNPLA3 PNPLA3 Q9NST1 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 chr22 Not Cancer Driver No 1 intact, hippie 54 33 7 7 0
PPM1B PPM1B O75688 Protein phosphatase 1B chr2 Not Cancer Driver No 1 hippie, biogrid 65 243 31 31 0
PROSER2 PROSER2 Q86WR7 Proline and serine-rich protein 2 chr10 Not Cancer Driver No 2 intact, hippie, biogrid 30 423 29 29 0
PRR4 PRR4 Q16378 Proline-rich protein 4 chr12 Not Cancer Driver No 2 intact, hippie, biogrid 25 125 25 25 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 Census, Compendium Yes 1 hippie 505 76 4 4 41
PTPRQ_ENST00000616559 PTPRQ Q9UMZ3 Phosphatidylinositol phosphatase PTPRQ chr12 Not Cancer Driver No 2 intact, hippie 143 362 22 22 1
RASSF1 RASSF1 Q9NS23 Ras association domain-containing protein 1 chr3 Not Cancer Driver No 3 hippie, biogrid 36 79 3 3 0
RELA RELA Q04206 Transcription factor p65 chr11 Compendium Yes 1 hippie 75 400 48 48 0
RHOC_ENST00000369642 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 Not Cancer Driver No 1 hippie 30 53 7 7 0
RNF31 RNF31 Q96EP0 E3 ubiquitin-protein ligase RNF31 chr14 Not Cancer Driver No 1 hippie 142 319 45 45 0
RPL35A RPL35A P18077 60S ribosomal protein L35a chr3 Not Cancer Driver No 1 hippie, biogrid 9 25 0 0 1
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 Not Cancer Driver No 1 hippie 94 178 32 32 0
SCGB1D1 SCGB1D1 O95968 Secretoglobin family 1D member 1 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 22 0 0 0 0
SCGB2A1 SCGB2A1 O75556 Mammaglobin-B chr11 Not Cancer Driver No 2 hippie, biogrid 14 0 0 0 0
SELP SELP P16109 P-selectin chr1 Not Cancer Driver No 1 hippie 226 14 2 2 0
SERPINA1 SERPINA1 P01009 Alpha-1-antitrypsin chr14 Not Cancer Driver No 2 intact, hippie, biogrid 66 38 7 7 0
SERPINA3_ENST00000393080 SERPINA3 P01011 Alpha-1-antichymotrypsin chr14 Not Cancer Driver No 2 hippie, biogrid 117 18 10 10 0
SLC2A1 SLC2A1 P11166 Solute carrier family 2, facilitated glucose transporter member 1 chr1 Not Cancer Driver No 1 hippie 51 13 2 2 48
SPANXN4 SPANXN4 Q5MJ08 Sperm protein associated with the nucleus on the X chromosome N4 chrX Not Cancer Driver No 1 hippie, biogrid 15 99 15 15 0
STEAP3_ENST00000393107 STEAP3 Q658P3 Metalloreductase STEAP3 chr2 Not Cancer Driver No 1 hippie 82 30 2 2 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
TACR3 TACR3 P29371 Neuromedin-K receptor chr4 Not Cancer Driver No 1 hippie, biogrid 137 31 17 17 5
TANC2 TANC2 Q9HCD6 Protein TANC2 chr17 Not Cancer Driver No 1 hippie, biogrid 278 999 127 127 1
TF TF P02787 Serotransferrin chr3 Not Cancer Driver No 2 hippie, biogrid 135 21 5 5 2
TGM1 TGM1 P22735 Protein-glutamine gamma-glutamyltransferase K chr14 Not Cancer Driver No 1 hippie, biogrid 118 230 37 37 65
TGOLN2_ENST00000377386 TGOLN2 O43493 Trans-Golgi network integral membrane protein 2 chr2 Not Cancer Driver No 1 intact, hippie 51 399 46 46 0
TIGD6_ENST00000515406 TIGD6 Q17RP2 Tigger transposable element-derived protein 6 chr5 Not Cancer Driver No 1 intact, hippie 30 64 4 4 0
TMEM74 TMEM74 Q96NL1 Transmembrane protein 74 chr8 Not Cancer Driver No 1 hippie, biogrid 93 127 42 42 0
TNF TNF P01375 Tumor necrosis factor chr6 Not Cancer Driver No 1 hippie 24 45 3 3 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
TTR TTR P02766 Transthyretin chr18 Not Cancer Driver No 2 hippie, biogrid 28 25 8 8 75
USB1 USB1 Q9BQ65 U6 snRNA phosphodiesterase 1 chr16 Not Cancer Driver No 1 intact, hippie 28 76 5 5 0
VPS26A_ENST00000263559 VPS26A O75436 Vacuolar protein sorting-associated protein 26A chr10 Not Cancer Driver No 1 hippie 27 44 2 2 0
VPS26B VPS26B Q4G0F5 Vacuolar protein sorting-associated protein 26B chr11 Not Cancer Driver No 3 hippie, biogrid 45 52 5 5 0
VPS35 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 Not Cancer Driver No 1 hippie 68 99 9 9 1
ZG16B ZG16B Q96DA0 Zymogen granule protein 16 homolog B chr16 Not Cancer Driver No 2 intact, hippie, biogrid 28 36 2 2 0
ZNF512B ZNF512B Q96KM6 Zinc finger protein 512B chr20 Not Cancer Driver No 1 hippie, biogrid 101 694 83 83 0
ZNF622 ZNF622 Q969S3 Zinc finger protein 622 chr5 Not Cancer Driver No 1 hippie 66 220 33 33 0