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SMYD3 ,SMYD3 ,Q9H7B4
  • Uniprot Accession= Q9H7B4
  • Ensembl Transcript= ENST00000490107.5
  • Uniprot Name= SMYD3
  • Name= Histone-lysine N-methyltransferase SMYD3
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 39
  • Number of Interaction partner in biogrid: 28
  • Number of Interaction partner in hippie: 61
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ALDH3A2_ENST00000579855 ALDH3A2 P51648 Aldehyde dehydrogenase family 3 member A2 chr17 Not Cancer Driver No 1 hippie, biogrid 47 5 2 2 26
AMY1A AMY1A P0DUB6 Alpha-amylase 1A chr1 Not Cancer Driver No 1 intact, hippie, biogrid 20 29 0 0 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
CAMK2B CAMK2B Q13554 Calcium/calmodulin-dependent protein kinase type II subunit beta chr7 Not Cancer Driver No 1 intact, hippie 86 273 28 28 6
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 1 intact, hippie 52 214 31 31 0
CNTN2 CNTN2 Q02246 Contactin-2 chr1 Not Cancer Driver No 1 hippie 155 370 61 61 0
CSTF2T CSTF2T Q9H0L4 Cleavage stimulation factor subunit 2 tau variant chr10 Not Cancer Driver No 1 hippie 87 507 75 75 0
CYP39A1 CYP39A1 Q9NYL5 24-hydroxycholesterol 7-alpha-hydroxylase chr6 Not Cancer Driver No 1 intact, hippie 61 3 0 0 0
DDOST_ENST00000375048 DDOST P39656 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit chr1 Not Cancer Driver No 1 intact, hippie 34 13 3 3 1
EED_ENST00000263360 EED O75530 Polycomb protein EED chr11 Census Yes 1 hippie 64 79 11 11 6
EEF1AKMT3 EEF1AKMT3 Q96AZ1 EEF1A lysine methyltransferase 3 chr12 Not Cancer Driver No 1 hippie 23 33 1 1 0
ENKD1 ENKD1 Q9H0I2 Enkurin domain-containing protein 1 chr16 Not Cancer Driver No 1 intact, hippie 40 307 34 34 0
ENPP1 ENPP1 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 148 101 5 5 33
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 Census, Compendium Yes 1 hippie 120 284 44 44 11
FAR1 FAR1 Q8WVX9 Fatty acyl-CoA reductase 1 chr11 Not Cancer Driver No 1 hippie 66 0 0 0 4
GYG2 GYG2 O15488 Glycogenin-2 chrX Not Cancer Driver No 1 hippie, biogrid 70 217 28 28 0
H3F3C H3-5 Q6NXT2 Histone H3.3C chr12 Not Cancer Driver No 1 intact 38 50 10 10 0
HELZ_ENST00000358691 HELZ P42694 Probable helicase with zinc finger domain chr17 Not Cancer Driver No 1 hippie 234 873 110 110 0
HIST1H4A H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 15 31 5 5 0
HIST1H4B H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 29 31 6 6 0
HIST1H4C H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 29 31 7 7 0
HIST1H4D H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 32 31 8 8 0
HIST1H4E H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 45 31 14 14 0
HIST1H4F H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 30 31 7 7 0
HIST1H4H H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 22 31 9 9 0
HIST1H4I H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 33 31 10 10 0
HIST1H4J H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 26 31 9 9 0
HIST1H4K H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 44 31 13 13 0
HIST1H4L H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 25 31 14 14 0
HIST4H4 H4-16 P62805 Histone H4 chr12 Not Cancer Driver No 1 intact 21 31 7 7 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 4 hippie, biogrid 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 3 intact, hippie, biogrid 100 254 43 43 0
KDM3B KDM3B Q7LBC6 Lysine-specific demethylase 3B chr5 Compendium Yes 2 intact, hippie, biogrid 221 943 114 114 7
KMT2E KMT2E Q8IZD2 Inactive histone-lysine N-methyltransferase 2E chr7 Not Cancer Driver No 1 hippie 233 1613 198 198 4
MAGED4B_ENST00000335504 MAGED4B Q96JG8 Melanoma-associated antigen D4 chrX Not Cancer Driver No 1 biogrid 1 415 0 0 0
MAGED4_ENST00000375626 MAGED4B Q96JG8 Melanoma-associated antigen D4 chrX Not Cancer Driver No 1 biogrid 0 415 0 0 0
MAP3K2_ENST00000344908 MAP3K2 Q9Y2U5 Mitogen-activated protein kinase kinase kinase 2 chr2 Not Cancer Driver No 1 intact, hippie 75 313 47 47 0
MEST MEST Q5EB52 Mesoderm-specific transcript homolog protein chr7 Not Cancer Driver No 1 hippie, biogrid 34 0 0 0 0
MKRN3 MKRN3 Q13064 Probable E3 ubiquitin-protein ligase makorin-3 chr15 Not Cancer Driver No 1 intact, hippie 197 201 99 99 4
MRPL23 MRPL23 Q16540 39S ribosomal protein L23, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 29 68 12 12 0
MRPL24_ENST00000368211 MRPL24 Q96A35 39S ribosomal protein L24, mitochondrial chr1 Not Cancer Driver No 1 intact, hippie, biogrid 22 71 7 7 0
MRPL27 MRPL27 Q9P0M9 39S ribosomal protein L27, mitochondrial chr17 Not Cancer Driver No 1 intact 16 35 2 2 0
MRPL28_ENST00000389675 MRPL28 Q13084 39S ribosomal protein L28, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 21 52 3 3 0
MRPL41 MRPL41 Q8IXM3 39S ribosomal protein L41, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 18 23 1 1 0
MRPL47 MRPL47 Q9HD33 39S ribosomal protein L47, mitochondrial chr3 Not Cancer Driver No 1 intact, hippie, biogrid 44 34 7 7 0
NDUFAB1_ENST00000007516 NDUFAB1 O14561 Acyl carrier protein, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie 23 0 0 0 0
NFYB NFYB P25208 Nuclear transcription factor Y subunit beta chr12 Not Cancer Driver No 1 intact, hippie 23 94 7 7 0
NME1_ENST00000393196 NME1 P15531 Nucleoside diphosphate kinase A chr17 Not Cancer Driver No 1 hippie, biogrid 11 10 0 0 0
NTMT1_ENST00000613644 NTMT1 Q9BV86 N-terminal Xaa-Pro-Lys N-methyltransferase 1 chr9 Not Cancer Driver No 1 hippie, biogrid 27 1 0 0 0
NUP54 NUP54 Q7Z3B4 Nucleoporin p54 chr4 Not Cancer Driver No 1 hippie 42 233 25 25 0
PBX2 PBX2 P40425 Pre-B-cell leukemia transcription factor 2 chr6 Not Cancer Driver No 1 intact, hippie 57 297 43 43 0
PKN1_ENST00000242783 PKN1 Q16512 Serine/threonine-protein kinase N1 chr19 Not Cancer Driver No 1 intact, hippie 120 459 54 54 0
PLCB3 PLCB3 Q01970 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 chr11 Not Cancer Driver No 1 hippie, biogrid 144 595 68 68 1
POLR2A POLR2A P24928-2 Isoform 2 of DNA-directed RNA polymerase II subunit RPB1 chr17 Census Yes 1 hippie 56 230 20 20 0
POLR2K POLR2K P53803 DNA-directed RNA polymerases I, II, and III subunit RPABC4 chr8 Not Cancer Driver No 1 hippie 10 11 1 1 0
PTGER3_ENST00000370931 PTGER3 P43115 Prostaglandin E2 receptor EP3 subtype chr1 Not Cancer Driver No 1 hippie, biogrid 79 17 2 2 0
PTGES3_ENST00000262033 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 Not Cancer Driver No 1 hippie, biogrid 11 52 3 3 0
RCAN3_ENST00000538532 RCAN3 Q9UKA8 Calcipressin-3 chr1 Not Cancer Driver No 3 hippie, biogrid 34 121 18 18 0
RPL27_ENST00000253788 RPL27 P61353 60S ribosomal protein L27 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 21 13 3 3 0
RPL7A RPL7A P62424 60S ribosomal protein L7a chr9 Not Cancer Driver No 1 intact, hippie, biogrid 27 100 5 5 0
RPLP2_ENST00000530797 RPLP2 P05387 60S acidic ribosomal protein P2 chr11 Not Cancer Driver No 1 intact, hippie, biogrid 12 59 5 5 0
RPS27L RPS27L Q71UM5 40S ribosomal protein S27-like chr15 Not Cancer Driver No 1 intact, hippie, biogrid 4 22 2 2 0
SHC3 SHC3 Q92529 SHC-transforming protein 3 chr9 Not Cancer Driver No 1 hippie 94 432 64 64 0
SMYD1 SMYD1 Q8NB12 Histone-lysine N-methyltransferase SMYD1 chr2 Not Cancer Driver No 1 hippie, biogrid 116 31 9 9 0
TMA7 TMA7 Q9Y2S6 Translation machinery-associated protein 7 chr3 Not Cancer Driver No 1 intact, hippie 3 64 3 3 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TRIT1 TRIT1 Q9H3H1 tRNA dimethylallyltransferase chr1 Not Cancer Driver No 1 hippie 61 121 19 19 1
TRMT2A_ENST00000403707 TRMT2A Q8IZ69 tRNA (uracil-5-)-methyltransferase homolog A chr22 Not Cancer Driver No 1 hippie, biogrid 64 157 20 20 0
TUBA1B TUBA1B P68363 Tubulin alpha-1B chain chr12 Not Cancer Driver No 1 intact, hippie, biogrid 41 52 9 9 0
UBE2R2 UBE2R2 Q712K3 Ubiquitin-conjugating enzyme E2 R2 chr9 Not Cancer Driver No 1 hippie 28 104 15 15 0
VANGL1 VANGL1 Q8TAA9 Vang-like protein 1 chr1 Not Cancer Driver No 1 hippie 72 140 15 15 3
XDH XDH P47989 Xanthine dehydrogenase/oxidase chr2 Not Cancer Driver No 1 hippie 279 134 24 24 1
ZIC1 ZIC1 Q15915 Zinc finger protein ZIC 1 chr3 Not Cancer Driver No 1 intact, hippie 187 246 113 113 1
ZNF557_ENST00000414706 ZNF557 Q8N988 Zinc finger protein 557 chr19 Not Cancer Driver No 1 hippie 81 115 25 25 0
ZNF57 ZNF57 Q68EA5 Zinc finger protein 57 chr19 Not Cancer Driver No 1 intact, hippie 79 112 16 16 0