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SMG5 ,SMG5 ,Q9UPR3
  • Uniprot Accession= Q9UPR3
  • Ensembl Transcript= ENST00000361813.5
  • Uniprot Name= SMG5
  • Name= Nonsense-mediated mRNA decay factor SMG5
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 10
  • Number of Interaction partner in biogrid: 5
  • Number of Interaction partner in hippie: 70
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
ANKRD17 ANKRD17 O75179 Ankyrin repeat domain-containing protein 17 chr4 Not Cancer Driver No 1 hippie 312 1790 221 221 9
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 Not Cancer Driver No 1 hippie 80 45 4 4 0
C6orf141 C6orf141 Q5SZD1 Uncharacterized protein C6orf141 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 12 226 9 9 0
CCDC96 CCDC96 Q2M329 Coiled-coil domain-containing protein 96 chr4 Not Cancer Driver No 1 hippie, biogrid 74 308 41 41 0
CELF1_ENST00000358597 CELF1 Q92879 CUGBP Elav-like family member 1 chr11 Not Cancer Driver No 1 hippie 56 166 17 17 0
CEP152 CEP152 O94986 Centrosomal protein of 152 kDa chr15 Not Cancer Driver No 1 intact, hippie 204 986 110 110 2
CEP85 CEP85 Q6P2H3 Centrosomal protein of 85 kDa chr1 Not Cancer Driver No 1 hippie 77 607 60 60 0
CNOT2 CNOT2 Q9NZN8 CCR4-NOT transcription complex subunit 2 chr12 Not Cancer Driver No 1 hippie 84 354 66 66 0
CNOT6L CNOT6L Q96LI5 CCR4-NOT transcription complex subunit 6-like chr4 Not Cancer Driver No 1 hippie 58 37 3 3 0
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 Not Cancer Driver No 1 hippie 31 21 1 1 0
CNOT9_ENST00000273064 CNOT9 Q92600 CCR4-NOT transcription complex subunit 9 chr2 Compendium Yes 1 hippie 42 30 0 0 0
CPEB1_ENST00000611031 CPEB1 Q9BZB8 Cytoplasmic polyadenylation element-binding protein 1 chr15 Not Cancer Driver No 1 intact, hippie 90 226 37 37 0
CPEB4 CPEB4 Q17RY0 Cytoplasmic polyadenylation element-binding protein 4 chr5 Not Cancer Driver No 1 hippie 85 443 54 54 0
DAZL_ENST00000399444 DAZL Q92904 Deleted in azoospermia-like chr3 Not Cancer Driver No 1 hippie 28 128 12 12 0
DCP1A DCP1A Q9NPI6 mRNA-decapping enzyme 1A chr3 Not Cancer Driver No 1 hippie 46 382 31 31 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 intact, hippie 132 514 82 82 0
DUSP16 DUSP16 Q9BY84 Dual specificity protein phosphatase 16 chr12 Compendium Yes 1 hippie, biogrid 70 273 34 34 0
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EIF4ENIF1 EIF4ENIF1 Q9NRA8 Eukaryotic translation initiation factor 4E transporter chr22 Not Cancer Driver No 1 hippie 116 899 101 101 0
FAM120C FAM120C Q9NX05 Constitutive coactivator of PPAR-gamma-like protein 2 chrX Not Cancer Driver No 1 hippie 162 508 77 77 0
FUBP3 FUBP3 Q96I24 Far upstream element-binding protein 3 chr9 Not Cancer Driver No 1 hippie 68 353 51 51 0
FXR1 FXR1 P51114 Fragile X mental retardation syndrome-related protein 1 chr3 Not Cancer Driver No 1 hippie 88 312 53 53 0
HDAC8 HDAC8 Q9BY41 Histone deacetylase 8 chrX Not Cancer Driver No 1 hippie 54 32 4 4 4
HIST1H2BL H2BC13 Q99880 Histone H2B type 1-L chr6 Not Cancer Driver No 1 intact 34 74 20 20 0
HIST2H2BE H2BC21 Q16778 Histone H2B type 2-E chr1 Not Cancer Driver No 1 intact 47 77 30 30 0
IGF2BP2_ENST00000382199 IGF2BP2 Q9Y6M1 Insulin-like growth factor 2 mRNA-binding protein 2 chr3 Census Yes 1 hippie 68 237 31 31 0
LSM14A_ENST00000433627 LSM14A Q8ND56 Protein LSM14 homolog A chr19 Census Yes 1 hippie 67 408 63 63 0
LZTS2 LZTS2 Q9BRK4 Leucine zipper putative tumor suppressor 2 chr10 Not Cancer Driver No 1 hippie 78 508 66 66 0
MEX3B MEX3B Q6ZN04 RNA-binding protein MEX3B chr15 Not Cancer Driver No 1 hippie 85 437 64 64 0
MKRN2 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 Not Cancer Driver No 1 hippie 45 145 16 16 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MRPS18C MRPS18C Q9Y3D5 28S ribosomal protein S18c, mitochondrial chr4 Not Cancer Driver No 1 hippie, biogrid 16 5 1 1 0
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
OTUD4_ENST00000447906 OTUD4 Q01804 OTU domain-containing protein 4 chr4 Not Cancer Driver No 1 hippie 148 788 120 120 0
PATL1 PATL1 Q86TB9 Protein PAT1 homolog 1 chr11 Not Cancer Driver No 1 hippie 79 499 49 49 0
PCM1 PCM1 Q15154 Pericentriolar material 1 protein chr8 Census Yes 1 intact, hippie 152 1665 134 134 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PRRC2A_ENST00000376007 PRRC2A P48634 Protein PRRC2A chr6 Not Cancer Driver No 1 hippie 253 2119 249 249 0
PUM1_ENST00000257075 PUM1 Q14671 Pumilio homolog 1 chr1 Not Cancer Driver No 1 hippie 150 640 77 77 3
R3HDM2_ENST00000358907 R3HDM2 Q9Y2K5 R3H domain-containing protein 2 chr12 Not Cancer Driver No 1 hippie 78 836 66 66 0
RBM47_ENST00000295971 RBM47 A0AV96 RNA-binding protein 47 chr4 Not Cancer Driver No 1 hippie 143 131 28 28 0
RBM8A_ENST00000632555 RBM8A Q9Y5S9 RNA-binding protein 8A chr1 Not Cancer Driver No 1 hippie 35 135 32 32 0
RBMS1 RBMS1 P29558 RNA-binding motif, single-stranded-interacting protein 1 chr2 Not Cancer Driver No 1 hippie 55 243 36 36 0
RIPK4_ENST00000352483 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 hippie 119 232 34 34 3
RNF214_ENST00000531452 RNF214 Q8ND24 RING finger protein 214 chr11 Not Cancer Driver No 1 hippie 84 528 66 66 0
SAMD4B SAMD4B Q5PRF9 Protein Smaug homolog 2 chr19 Not Cancer Driver No 1 hippie 79 467 57 57 0
SMAP2 SMAP2 Q8WU79 Stromal membrane-associated protein 2 chr1 Not Cancer Driver No 1 hippie 50 214 30 30 0
SMG1 SMG1 Q96Q15 Serine/threonine-protein kinase SMG1 chr16 Not Cancer Driver No 1 hippie 348 605 73 73 0
SMG6 SMG6 Q86US8 Telomerase-binding protein EST1A chr17 Not Cancer Driver No 1 hippie 166 751 97 97 0
SMG7_ENST00000347615 SMG7 Q92540 Nonsense-mediated mRNA decay factor SMG7 chr1 Not Cancer Driver No 1 hippie 134 664 82 82 0
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 Not Cancer Driver No 1 hippie 35 112 14 14 12
SYT2_ENST00000367268 SYT2 Q8N9I0 Synaptotagmin-2 chr1 Not Cancer Driver No 1 hippie, biogrid 73 141 24 24 3
TDRD3_ENST00000196169 TDRD3 Q9H7E2 Tudor domain-containing protein 3 chr13 Not Cancer Driver No 1 hippie 97 518 77 77 0
TERT TERT O14746 Telomerase reverse transcriptase chr5 Census Yes 1 intact, hippie 110 212 16 16 31
TNRC6A TNRC6A Q8NDV7 Trinucleotide repeat-containing gene 6A protein chr16 Not Cancer Driver No 1 hippie 284 1830 265 265 0
TNRC6B TNRC6B Q9UPQ9 Trinucleotide repeat-containing gene 6B protein chr22 Not Cancer Driver No 1 hippie 205 1735 195 195 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 3 intact, hippie 2891 282 1466 1466 83
UBAP2L UBAP2L Q14157 Ubiquitin-associated protein 2-like chr1 Not Cancer Driver No 1 hippie 129 1039 128 128 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 hippie 82 581 79 79 8
UNK UNK Q9C0B0 RING finger protein unkempt homolog chr17 Not Cancer Driver No 1 hippie 79 511 46 46 0
UPF1 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 Not Cancer Driver No 3 intact, hippie 146 329 36 36 0
UPF3A UPF3A Q9H1J1 Regulator of nonsense transcripts 3A chr13 Not Cancer Driver No 1 hippie 31 378 21 21 0
UPF3B UPF3B Q9BZI7 Regulator of nonsense transcripts 3B chrX Not Cancer Driver No 1 hippie 98 428 91 91 1
XRN1 XRN1 Q8IZH2 5'-3' exoribonuclease 1 chr3 Not Cancer Driver No 1 hippie 213 577 65 65 0
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 Not Cancer Driver No 1 hippie 67 376 44 44 0
YTHDF3_ENST00000539294 YTHDF3 Q7Z739 YTH domain-containing family protein 3 chr8 Not Cancer Driver No 1 hippie 74 409 51 51 0
ZC3H7A_ENST00000355758 ZC3H7A Q8IWR0 Zinc finger CCCH domain-containing protein 7A chr16 Not Cancer Driver No 1 hippie 91 224 23 23 0
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 Not Cancer Driver No 1 hippie 43 262 34 34 0
ZWINT ZWINT O95229 ZW10 interactor chr10 Not Cancer Driver No 1 hippie 65 168 44 44 0