Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ABCE1 | ABCE1 | P61221 | ATP-binding cassette sub-family E member 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 74 | 36 | 6 | 6 | 0 |
ACIN1 | ACIN1 | Q9UKV3 | Apoptotic chromatin condensation inducer in the nucleus | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 157 | 1294 | 155 | 155 | 0 |
ADAR | ADAR | P55265 | Double-stranded RNA-specific adenosine deaminase | chr1 | Not Cancer Driver | No | 1 | hippie | 149 | 675 | 83 | 83 | 12 |
AIRE | AIRE | O43918 | Autoimmune regulator | chr21 | Not Cancer Driver | No | 1 | hippie | 71 | 338 | 48 | 48 | 19 |
AKR7A2 | AKR7A2 | O43488 | Aflatoxin B1 aldehyde reductase member 2 | chr1 | Not Cancer Driver | No | 1 | hippie | 35 | 90 | 3 | 3 | 0 |
ALB | ALB | P02768 | Albumin | chr4 | Compendium | Yes | 1 | hippie | 162 | 6 | 0 | 0 | 3 |
ALPI | ALPI | P09923 | Intestinal-type alkaline phosphatase | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 94 | 157 | 36 | 36 | 0 |
AMOT | AMOT | Q4VCS5 | Angiomotin | chrX | Not Cancer Driver | No | 1 | intact, hippie | 161 | 909 | 128 | 128 | 0 |
ANAPC2 | ANAPC2 | Q9UJX6 | Anaphase-promoting complex subunit 2 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 104 | 146 | 26 | 26 | 0 |
ANKRD11_ENST00000642600 | ANKRD11 | Q6UB99 | Ankyrin repeat domain-containing protein 11 | chr16 | Not Cancer Driver | No | 1 | hippie | 362 | 2289 | 299 | 299 | 0 |
ANKRD28 | ANKRD28 | O15084 | Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A | chr3 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 121 | 115 | 15 | 15 | 0 |
ANKRD55 | ANKRD55 | Q3KP44 | Ankyrin repeat domain-containing protein 55 | chr5 | Not Cancer Driver | No | 1 | hippie | 95 | 339 | 63 | 63 | 0 |
ANLN | ANLN | Q9NQW6 | Anillin | chr7 | Not Cancer Driver | No | 1 | hippie | 144 | 767 | 104 | 104 | 2 |
ARHGAP36 | ARHGAP36 | Q6ZRI8 | Rho GTPase-activating protein 36 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 194 | 132 | 61 | 61 | 0 |
ARHGEF10L | ARHGEF10L | Q9HCE6 | Rho guanine nucleotide exchange factor 10-like protein | chr1 | Census, Compendium | Yes | 1 | hippie, biogrid | 155 | 431 | 47 | 47 | 0 |
ARHGEF4 | ARHGEF4 | Q9NR80 | Rho guanine nucleotide exchange factor 4 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 114 | 287 | 61 | 61 | 0 |
ARMCX3_ENST00000537169 | ARMCX3 | Q9UH62 | Armadillo repeat-containing X-linked protein 3 | chrX | Not Cancer Driver | No | 1 | hippie | 39 | 77 | 7 | 7 | 0 |
ATG16L1 | ATG16L1 | Q676U5 | Autophagy-related protein 16-1 | chr2 | Not Cancer Driver | No | 1 | hippie | 79 | 239 | 25 | 25 | 1 |
ATG2A | ATG2A | Q2TAZ0 | Autophagy-related protein 2 homolog A | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 228 | 887 | 124 | 124 | 0 |
ATG4C_ENST00000371120 | ATG4C | Q96DT6 | Cysteine protease ATG4C | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 62 | 17 | 3 | 3 | 0 |
ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | Census, Compendium | Yes | 1 | intact, hippie | 469 | 225 | 39 | 39 | 41 |
ATR | ATR | Q13535 | Serine/threonine-protein kinase ATR | chr3 | Census, Compendium | Yes | 1 | hippie | 338 | 106 | 14 | 14 | 1 |
ATRX | ATRX | P46100 | Transcriptional regulator ATRX | chrX | Census, Compendium | Yes | 1 | intact, hippie | 487 | 1672 | 301 | 301 | 33 |
AURKAIP1_ENST00000321751 | AURKAIP1 | Q9NWT8 | Aurora kinase A-interacting protein | chr1 | Not Cancer Driver | No | 1 | hippie | 18 | 104 | 8 | 8 | 0 |
AURKB_ENST00000585124 | AURKB | Q96GD4 | Aurora kinase B | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 63 | 8 | 8 | 0 |
BARD1 | BARD1 | Q99728 | BRCA1-associated RING domain protein 1 | chr2 | Census | Yes | 1 | hippie | 96 | 384 | 49 | 49 | 0 |
BECN1_ENST00000590099 | BECN1 | Q14457 | Beclin-1 | chr17 | Not Cancer Driver | No | 1 | hippie | 45 | 190 | 19 | 19 | 0 |
BET1 | BET1 | O15155 | BET1 homolog | chr7 | Not Cancer Driver | No | 1 | hippie | 14 | 7 | 2 | 2 | 0 |
BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | Census, Compendium | Yes | 1 | hippie | 77 | 98 | 16 | 16 | 0 |
BLM | BLM | P54132 | Bloom syndrome protein | chr15 | Census | Yes | 1 | hippie | 153 | 667 | 70 | 70 | 8 |
BMI1 | BMI1 | P35226 | Polycomb complex protein BMI-1 | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 50 | 150 | 30 | 30 | 0 |
BPTF_ENST00000321892 | BPTF | Q12830 | Nucleosome-remodeling factor subunit BPTF | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 309 | 2187 | 218 | 218 | 2 |
BRCA1_ENST00000357654 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | Census, Compendium | Yes | 1 | intact, hippie | 224 | 1458 | 174 | 174 | 35 |
BRD4 | BRD4 | O60885 | Bromodomain-containing protein 4 | chr19 | Census, Compendium | Yes | 1 | hippie | 193 | 1182 | 172 | 172 | 0 |
BRD7_ENST00000394688 | BRD7 | Q9NPI1 | Bromodomain-containing protein 7 | chr16 | Compendium | Yes | 1 | hippie | 82 | 482 | 57 | 57 | 0 |
CAMK2D_ENST00000342666 | CAMK2D | Q13557 | Calcium/calmodulin-dependent protein kinase type II subunit delta | chr4 | Not Cancer Driver | No | 1 | hippie | 57 | 84 | 10 | 10 | 0 |
CAMKK2 | CAMKK2 | Q96RR4 | Calcium/calmodulin-dependent protein kinase kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 65 | 281 | 35 | 35 | 0 |
CASP4 | CASP4 | P49662 | Caspase-4 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 102 | 14 | 14 | 0 |
CCDC175 | CCDC175 | P0C221 | Coiled-coil domain-containing protein 175 | chr14 | Not Cancer Driver | No | 1 | hippie | 25 | 83 | 2 | 2 | 0 |
CCDC8 | CCDC8 | Q9H0W5 | Coiled-coil domain-containing protein 8 | chr19 | Not Cancer Driver | No | 1 | hippie | 96 | 505 | 91 | 91 | 0 |
CCNF | CCNF | P41002 | Cyclin-F | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 106 | 221 | 23 | 23 | 3 |
CDC14A_ENST00000336454 | CDC14A | Q9UNH5 | Dual specificity protein phosphatase CDC14A | chr1 | Not Cancer Driver | No | 1 | hippie | 91 | 246 | 43 | 43 | 3 |
CDC34 | CDC34 | P49427 | Ubiquitin-conjugating enzyme E2 R1 | chr19 | Not Cancer Driver | No | 1 | hippie | 26 | 95 | 11 | 11 | 0 |
CDC5L | CDC5L | Q99459 | Cell division cycle 5-like protein | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 100 | 618 | 77 | 77 | 0 |
CDCA5 | CDCA5 | Q96FF9 | Sororin | chr11 | Not Cancer Driver | No | 2 | hippie, biogrid | 32 | 211 | 26 | 26 | 0 |
CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 0 |
CDK20 | CDK20 | Q8IZL9 | Cyclin-dependent kinase 20 | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 36 | 32 | 1 | 1 | 0 |
CDK4 | CDK4 | P11802 | Cyclin-dependent kinase 4 | chr12 | Census, Compendium | Yes | 1 | intact, hippie, biogrid | 52 | 52 | 5 | 5 | 3 |
CDK8 | CDK8 | P49336 | Cyclin-dependent kinase 8 | chr13 | Not Cancer Driver | No | 1 | hippie | 76 | 152 | 18 | 18 | 7 |
CEBPA | CEBPA | P49715 | CCAAT/enhancer-binding protein alpha | chr19 | Census, Compendium | Yes | 1 | hippie | 12 | 342 | 12 | 12 | 1 |
CFDP1 | CFDP1 | Q9UEE9 | Craniofacial development protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 273 | 18 | 18 | 0 |
CHD2 | CHD2 | O14647 | Chromodomain-helicase-DNA-binding protein 2 | chr15 | Census, Compendium | Yes | 1 | intact, hippie | 222 | 1051 | 136 | 136 | 2 |
CHD3_ENST00000330494 | CHD3 | Q12873 | Chromodomain-helicase-DNA-binding protein 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 235 | 1015 | 122 | 122 | 18 |
CHD4 | CHD4 | Q14839 | Chromodomain-helicase-DNA-binding protein 4 | chr12 | Census, Compendium | Yes | 1 | hippie | 419 | 974 | 177 | 177 | 6 |
CHEK2_ENST00000405598 | CHEK2 | O96017 | Serine/threonine-protein kinase Chk2 | chr22 | Census, Compendium | Yes | 1 | intact, hippie | 335 | 157 | 130 | 130 | 13 |
CHMP4C | CHMP4C | Q96CF2 | Charged multivesicular body protein 4c | chr8 | Not Cancer Driver | No | 1 | hippie | 33 | 224 | 31 | 31 | 0 |
CHTF18 | CHTF18 | Q8WVB6 | Chromosome transmission fidelity protein 18 homolog | chr16 | Not Cancer Driver | No | 1 | hippie | 114 | 503 | 56 | 56 | 0 |
CIC | CIC | Q96RK0 | Protein capicua homolog | chr19 | Census, Compendium | Yes | 1 | hippie | 276 | 1550 | 266 | 266 | 0 |
CITED1_ENST00000246139 | CITED1 | Q99966 | Cbp/p300-interacting transactivator 1 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 166 | 21 | 21 | 0 |
CIT_ENST00000261833 | CIT | O14578 | Citron Rho-interacting kinase | chr12 | Not Cancer Driver | No | 1 | hippie | 284 | 1017 | 160 | 160 | 3 |
CKAP5 | CKAP5 | Q14008 | Cytoskeleton-associated protein 5 | chr11 | Not Cancer Driver | No | 1 | hippie | 198 | 634 | 64 | 64 | 0 |
COIL | COIL | P38432 | Coilin | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 385 | 42 | 42 | 0 |
COPB1_ENST00000439561 | COPB1 | P53618 | Coatomer subunit beta | chr11 | Not Cancer Driver | No | 1 | hippie | 110 | 95 | 10 | 10 | 1 |
CSTF2_ENST00000372972 | CSTF2 | P33240 | Cleavage stimulation factor subunit 2 | chrX | Not Cancer Driver | No | 1 | intact, hippie | 85 | 484 | 72 | 72 | 0 |
CTCF | CTCF | P49711 | Transcriptional repressor CTCF | chr16 | Census, Compendium | Yes | 1 | hippie | 151 | 481 | 83 | 83 | 1 |
CUL3 | CUL3 | Q13618 | Cullin-3 | chr2 | Census, Compendium | Yes | 1 | intact, hippie | 123 | 167 | 23 | 23 | 3 |
CUL4A | CUL4A | Q13619 | Cullin-4A | chr13 | Not Cancer Driver | No | 1 | hippie | 64 | 102 | 2 | 2 | 0 |
CUL7_ENST00000265348 | CUL7 | Q14999 | Cullin-7 | chr6 | Not Cancer Driver | No | 1 | hippie | 188 | 372 | 41 | 41 | 3 |
DBP | DBP | Q10586 | D site-binding protein | chr19 | Not Cancer Driver | No | 1 | intact | 24 | 280 | 18 | 18 | 0 |
DCAF15 | DCAF15 | Q66K64 | DDB1- and CUL4-associated factor 15 | chr19 | Not Cancer Driver | No | 1 | hippie | 50 | 173 | 18 | 18 | 0 |
DCPS | DCPS | Q96C86 | m7GpppX diphosphatase | chr11 | Not Cancer Driver | No | 1 | hippie | 48 | 53 | 6 | 6 | 1 |
DDI1 | DDI1 | Q8WTU0 | Protein DDI1 homolog 1 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 151 | 166 | 73 | 73 | 0 |
DDX47 | DDX47 | Q9H0S4 | Probable ATP-dependent RNA helicase DDX47 | chr12 | Not Cancer Driver | No | 1 | hippie | 51 | 98 | 7 | 7 | 0 |
DERL1 | DERL1 | Q9BUN8 | Derlin-1 | chr8 | Not Cancer Driver | No | 1 | hippie | 28 | 11 | 1 | 1 | 0 |
DNM1 | DNM1 | Q05193 | Dynamin-1 | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 98 | 280 | 23 | 23 | 4 |
DNM2_ENST00000355667 | DNM2 | P50570 | Dynamin-2 | chr19 | Census | Yes | 1 | hippie | 138 | 270 | 43 | 43 | 22 |
DUSP2 | DUSP2 | Q05923 | Dual specificity protein phosphatase 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 24 | 23 | 3 | 3 | 0 |
DUSP26 | DUSP26 | Q9BV47 | Dual specificity protein phosphatase 26 | chr8 | Not Cancer Driver | No | 1 | hippie | 56 | 14 | 6 | 6 | 0 |
EED_ENST00000263360 | EED | O75530 | Polycomb protein EED | chr11 | Census | Yes | 1 | hippie | 64 | 79 | 11 | 11 | 6 |
EEF1A1 | EEF1A1 | P68104 | Elongation factor 1-alpha 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 109 | 100 | 14 | 14 | 0 |
EEF1AKMT3 | EEF1AKMT3 | Q96AZ1 | EEF1A lysine methyltransferase 3 | chr12 | Not Cancer Driver | No | 1 | hippie | 23 | 33 | 1 | 1 | 0 |
EFTUD2 | EFTUD2 | Q15029 | 116 kDa U5 small nuclear ribonucleoprotein component | chr17 | Compendium | Yes | 1 | hippie | 132 | 179 | 30 | 30 | 3 |
EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | Census, Compendium | Yes | 1 | hippie | 444 | 223 | 35 | 35 | 1 |
EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 13 | 0 | 0 | 0 |
EHMT2_ENST00000375537 | EHMT2 | Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | chr6 | Not Cancer Driver | No | 1 | hippie | 142 | 585 | 71 | 71 | 0 |
ELF1 | ELF1 | P32519 | ETS-related transcription factor Elf-1 | chr13 | Not Cancer Driver | No | 1 | hippie | 78 | 469 | 62 | 62 | 0 |
ELF2 | ELF2 | Q15723 | ETS-related transcription factor Elf-2 | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 59 | 423 | 43 | 43 | 0 |
EMILIN1 | EMILIN1 | Q9Y6C2 | EMILIN-1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 125 | 669 | 69 | 69 | 0 |
EN1 | EN1 | Q05925 | Homeobox protein engrailed-1 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 42 | 357 | 30 | 30 | 0 |
EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | Census, Compendium | Yes | 1 | hippie | 334 | 1790 | 196 | 196 | 1 |
EPS15L1_ENST00000248070 | EPS15L1 | Q9UBC2 | Epidermal growth factor receptor substrate 15-like 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 109 | 603 | 76 | 76 | 0 |
ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | hippie | 121 | 195 | 27 | 27 | 2 |
ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 90 | 92 | 11 | 11 | 1 |
ETV3 | ETV3 | P41162 | ETS translocation variant 3 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 48 | 330 | 24 | 24 | 0 |
EZH2_ENST00000460911 | EZH2 | Q15910 | Histone-lysine N-methyltransferase EZH2 | chr7 | Census, Compendium | Yes | 1 | hippie | 120 | 284 | 44 | 44 | 11 |
FAM174A | FAM174A | Q8TBP5 | Membrane protein FAM174A | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 140 | 21 | 21 | 0 |
FANCD2_ENST00000383807 | FANCD2 | Q9BXW9 | Fanconi anemia group D2 protein | chr3 | Census, Compendium | Yes | 1 | hippie | 176 | 181 | 14 | 14 | 3 |
FBXO6 | FBXO6 | Q9NRD1 | F-box only protein 6 | chr1 | Not Cancer Driver | No | 1 | hippie | 31 | 27 | 3 | 3 | 0 |
FBXW7_ENST00000603841 | FBXW7 | Q969H0 | F-box/WD repeat-containing protein 7 | chr4 | Census, Compendium | Yes | 1 | hippie | 322 | 230 | 38 | 38 | 0 |
FEV | FEV | Q99581 | Protein FEV | chr2 | Census | Yes | 1 | hippie | 15 | 55 | 0 | 0 | 0 |
FGF14_ENST00000376143 | FGF14 | Q92915 | Fibroblast growth factor 14 | chr13 | Not Cancer Driver | No | 1 | intact, hippie | 72 | 93 | 30 | 30 | 1 |
FGFR3_ENST00000440486 | FGFR3 | P22607 | Fibroblast growth factor receptor 3 | chr4 | Census, Compendium | Yes | 1 | intact | 173 | 241 | 26 | 26 | 37 |
FOXB1 | FOXB1 | Q99853 | Forkhead box protein B1 | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 31 | 114 | 5 | 5 | 0 |
FOXG1 | FOXG1 | P55316 | Forkhead box protein G1 | chr14 | Not Cancer Driver | No | 1 | hippie | 132 | 322 | 79 | 79 | 2 |
FOXJ2 | FOXJ2 | Q9P0K8 | Forkhead box protein J2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 81 | 483 | 65 | 65 | 0 |
FOXL1 | FOXL1 | Q12952 | Forkhead box protein L1 | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 62 | 212 | 26 | 26 | 0 |
FOXQ1 | FOXQ1 | Q9C009 | Forkhead box protein Q1 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 22 | 245 | 4 | 4 | 0 |
FTL | FTL | P02792 | Ferritin light chain | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 36 | 7 | 7 | 2 |
GABARAPL2 | GABARAPL2 | P60520 | Gamma-aminobutyric acid receptor-associated protein-like 2 | chr16 | Not Cancer Driver | No | 1 | hippie | 11 | 2 | 1 | 1 | 0 |
GANC | GANC | Q8TET4 | Neutral alpha-glucosidase C | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 104 | 61 | 3 | 3 | 0 |
GCC1 | GCC1 | Q96CN9 | GRIP and coiled-coil domain-containing protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 118 | 508 | 69 | 69 | 0 |
GCN1 | GCN1 | Q92616 | eIF-2-alpha kinase activator GCN1 | chr12 | Not Cancer Driver | No | 1 | hippie | 327 | 117 | 16 | 16 | 0 |
GOLGA2_ENST00000611957 | GOLGA2 | Q08379 | Golgin subfamily A member 2 | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 115 | 854 | 96 | 96 | 0 |
GRM3 | GRM3 | Q14832 | Metabotropic glutamate receptor 3 | chr7 | Census | Yes | 1 | intact, hippie | 323 | 8 | 3 | 3 | 0 |
GTF3C3 | GTF3C3 | Q9Y5Q9 | General transcription factor 3C polypeptide 3 | chr2 | Not Cancer Driver | No | 1 | hippie | 109 | 195 | 22 | 22 | 0 |
GTF3C4 | GTF3C4 | Q9UKN8 | General transcription factor 3C polypeptide 4 | chr9 | Not Cancer Driver | No | 2 | intact, hippie | 76 | 164 | 13 | 13 | 0 |
HAND2 | HAND2 | P61296 | Heart- and neural crest derivatives-expressed protein 2 | chr4 | Not Cancer Driver | No | 1 | hippie | 47 | 124 | 29 | 29 | 0 |
HAUS3 | HAUS3 | Q68CZ6 | HAUS augmin-like complex subunit 3 | chr4 | Not Cancer Driver | No | 1 | intact, hippie | 61 | 55 | 7 | 7 | 0 |
HDAC11 | HDAC11 | Q96DB2 | Histone deacetylase 11 | chr3 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 57 | 18 | 8 | 8 | 0 |
HDAC5_ENST00000586802 | HDAC5 | Q9UQL6 | Histone deacetylase 5 | chr17 | Not Cancer Driver | No | 1 | hippie | 118 | 718 | 73 | 73 | 0 |
HDAC8 | HDAC8 | Q9BY41 | Histone deacetylase 8 | chrX | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 54 | 32 | 4 | 4 | 4 |
HDDC3_ENST00000646620 | HDDC3 | Q8N4P3 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 13 | 76 | 9 | 9 | 0 |
HIP1R | HIP1R | O75146 | Huntingtin-interacting protein 1-related protein | chr12 | Not Cancer Driver | No | 1 | hippie | 94 | 524 | 34 | 34 | 0 |
HLTF_ENST00000494055 | HLTF | Q14527 | Helicase-like transcription factor | chr3 | Not Cancer Driver | No | 1 | hippie | 121 | 353 | 40 | 40 | 0 |
HNRNPA2B1 | HNRNPA2B1 | P22626 | Heterogeneous nuclear ribonucleoproteins A2/B1 | chr7 | Census, Compendium | Yes | 1 | intact, hippie | 68 | 255 | 41 | 41 | 0 |
HNRNPH1 | HNRNPH1 | P31943 | Heterogeneous nuclear ribonucleoprotein H | chr5 | Not Cancer Driver | No | 1 | hippie | 51 | 169 | 29 | 29 | 0 |
HNRNPU | HNRNPU | Q00839 | Heterogeneous nuclear ribonucleoprotein U | chr1 | Not Cancer Driver | No | 1 | hippie | 77 | 504 | 45 | 45 | 0 |
HSF1 | HSF1 | Q00613 | Heat shock factor protein 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 59 | 335 | 37 | 37 | 0 |
HSPA8_ENST00000532636 | HSPA8 | P11142 | Heat shock cognate 71 kDa protein | chr11 | Not Cancer Driver | No | 1 | hippie | 149 | 251 | 52 | 52 | 0 |
ILK_ENST00000299421 | ILK | Q13418 | Integrin-linked protein kinase | chr11 | Not Cancer Driver | No | 1 | hippie | 45 | 71 | 9 | 9 | 0 |
INTS3_ENST00000435409 | INTS3 | Q68E01 | Integrator complex subunit 3 | chr1 | Not Cancer Driver | No | 1 | hippie | 125 | 213 | 25 | 25 | 0 |
IRF3_ENST00000597198 | IRF3 | Q14653 | Interferon regulatory factor 3 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 36 | 204 | 21 | 21 | 1 |
ITLN1 | ITLN1 | Q8WWA0 | Intelectin-1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 72 | 13 | 4 | 4 | 0 |
IVNS1ABP | IVNS1ABP | Q9Y6Y0 | Influenza virus NS1A-binding protein | chr1 | Not Cancer Driver | No | 1 | hippie | 85 | 90 | 12 | 12 | 0 |
JUN | JUN | P05412 | Transcription factor Jun | chr1 | Census | Yes | 1 | hippie | 35 | 281 | 25 | 25 | 0 |
KCTD2 | KCTD2 | Q14681 | BTB/POZ domain-containing protein KCTD2 | chr17 | Not Cancer Driver | No | 1 | hippie | 34 | 128 | 11 | 11 | 0 |
KDM1B_ENST00000449850 | KDM1B | Q8NB78 | Lysine-specific histone demethylase 1B | chr6 | Not Cancer Driver | No | 1 | hippie | 81 | 74 | 11 | 11 | 0 |
KIAA1191_ENST00000510164 | KIAA1191 | Q96A73 | Putative monooxygenase p33MONOX | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 25 | 288 | 22 | 22 | 0 |
KIF13A | KIF13A | Q9H1H9 | Kinesin-like protein KIF13A | chr6 | Not Cancer Driver | No | 1 | hippie | 220 | 816 | 103 | 103 | 0 |
KIF14 | KIF14 | Q15058 | Kinesin-like protein KIF14 | chr1 | Not Cancer Driver | No | 1 | hippie | 222 | 774 | 102 | 102 | 2 |
KLF12 | KLF12 | Q9Y4X4 | Krueppel-like factor 12 | chr13 | Not Cancer Driver | No | 1 | hippie | 60 | 338 | 50 | 50 | 0 |
KLF16 | KLF16 | Q9BXK1 | Krueppel-like factor 16 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 13 | 204 | 8 | 8 | 0 |
KLHL20 | KLHL20 | Q9Y2M5 | Kelch-like protein 20 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 83 | 143 | 17 | 17 | 0 |
LARP7_ENST00000344442 | LARP7 | Q4G0J3 | La-related protein 7 | chr4 | Not Cancer Driver | No | 1 | hippie | 58 | 350 | 44 | 44 | 0 |
LHX2 | LHX2 | P50458 | LIM/homeobox protein Lhx2 | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 60 | 203 | 28 | 28 | 0 |
LIN9 | LIN9 | Q5TKA1 | Protein lin-9 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 67 | 219 | 25 | 25 | 0 |
LMNA | LMNA | P02545 | Prelamin-A/C | chr1 | Census | Yes | 1 | hippie | 68 | 544 | 49 | 49 | 131 |
LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 519 | 90 | 17 | 17 | 23 |
LSM14B | LSM14B | Q9BX40 | Protein LSM14 homolog B | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 50 | 320 | 42 | 42 | 0 |
MAD2L2 | MAD2L2 | Q9UI95 | Mitotic spindle assembly checkpoint protein MAD2B | chr1 | Not Cancer Driver | No | 1 | hippie | 22 | 0 | 0 | 0 | 1 |
MAP2K2 | MAP2K2 | P36507 | Dual specificity mitogen-activated protein kinase kinase 2 | chr19 | Census | Yes | 1 | hippie, biogrid | 58 | 105 | 14 | 14 | 4 |
MATR3_ENST00000509990 | MATR3 | P43243 | Matrin-3 | chr5 | Not Cancer Driver | No | 1 | hippie | 98 | 611 | 68 | 68 | 3 |
MAU2 | MAU2 | Q9Y6X3 | MAU2 chromatid cohesion factor homolog | chr19 | Not Cancer Driver | No | 1 | hippie | 68 | 36 | 1 | 1 | 0 |
MCM2 | MCM2 | P49736 | DNA replication licensing factor MCM2 | chr3 | Not Cancer Driver | No | 2 | intact, hippie | 104 | 275 | 38 | 38 | 1 |
MCM4 | MCM4 | P33991 | DNA replication licensing factor MCM4 | chr8 | Not Cancer Driver | No | 2 | intact, hippie | 121 | 215 | 35 | 35 | 0 |
MCM6 | MCM6 | Q14566 | DNA replication licensing factor MCM6 | chr2 | Not Cancer Driver | No | 2 | intact, hippie | 101 | 122 | 13 | 13 | 0 |
MCM7 | MCM7 | P33993 | DNA replication licensing factor MCM7 | chr7 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 101 | 128 | 22 | 22 | 0 |
MDC1 | MDC1 | Q14676 | Mediator of DNA damage checkpoint protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 249 | 1829 | 223 | 223 | 0 |
MECOM_ENST00000494292 | MECOM | Q03112 | Histone-lysine N-methyltransferase MECOM | chr3 | Census, Compendium | Yes | 1 | hippie | 287 | 749 | 159 | 159 | 3 |
MET_ENST00000397752 | MET | P08581 | Hepatocyte growth factor receptor | chr7 | Census, Compendium | Yes | 1 | hippie | 226 | 62 | 15 | 15 | 19 |
MEX3C | MEX3C | Q5U5Q3 | RNA-binding E3 ubiquitin-protein ligase MEX3C | chr18 | Not Cancer Driver | No | 1 | intact, hippie | 54 | 475 | 32 | 32 | 0 |
MGA | MGA | Q8IWI9 | MAX gene-associated protein | chr15 | Compendium | Yes | 1 | hippie | 341 | 2317 | 259 | 259 | 0 |
MGARP | MGARP | Q8TDB4 | Protein MGARP | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 207 | 22 | 22 | 0 |
MGME1 | MGME1 | Q9BQP7 | Mitochondrial genome maintenance exonuclease 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 33 | 95 | 7 | 7 | 1 |
MGMT | MGMT | B4DEE8 | Methylated-DNA--protein-cysteine methyltransferase | chr10 | Census | Yes | 1 | hippie | 43 | 40 | 15 | 15 | 0 |
MKI67 | MKI67 | P46013 | Proliferation marker protein Ki-67 | chr10 | Not Cancer Driver | No | 1 | hippie | 540 | 3169 | 529 | 529 | 0 |
MKRN1 | MKRN1 | Q9UHC7 | E3 ubiquitin-protein ligase makorin-1 | chr7 | Not Cancer Driver | No | 1 | hippie | 42 | 155 | 16 | 16 | 0 |
MLH1 | MLH1 | P40692 | DNA mismatch repair protein Mlh1 | chr3 | Census | Yes | 1 | hippie | 92 | 208 | 22 | 22 | 85 |
MRPL50 | MRPL50 | Q8N5N7 | 39S ribosomal protein L50, mitochondrial | chr9 | Not Cancer Driver | No | 1 | hippie | 27 | 3 | 0 | 0 | 0 |
MSH2 | MSH2 | P43246 | DNA mismatch repair protein Msh2 | chr2 | Census | Yes | 1 | hippie | 92 | 37 | 4 | 4 | 70 |
MSH6 | MSH6 | P52701 | DNA mismatch repair protein Msh6 | chr2 | Census | Yes | 1 | hippie | 154 | 386 | 41 | 41 | 6 |
MST1R | MST1R | Q04912 | Macrophage-stimulating protein receptor | chr3 | Not Cancer Driver | No | 1 | intact | 178 | 182 | 27 | 27 | 1 |
MTF1 | MTF1 | Q14872 | Metal regulatory transcription factor 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 115 | 553 | 76 | 76 | 0 |
MTUS1 | MTUS1 | Q9ULD2 | Microtubule-associated tumor suppressor 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 127 | 978 | 106 | 106 | 4 |
MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
NCL | NCL | P19338 | Nucleolin | chr2 | Not Cancer Driver | No | 1 | hippie | 85 | 569 | 68 | 68 | 0 |
NDC80 | NDC80 | O14777 | Kinetochore protein NDC80 homolog | chr18 | Not Cancer Driver | No | 2 | hippie, biogrid | 80 | 313 | 45 | 45 | 0 |
NDN | NDN | Q99608 | Necdin | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 123 | 117 | 42 | 42 | 0 |
NEDD8 | NEDD8 | Q15843 | NEDD8 | chr14 | Not Cancer Driver | No | 1 | hippie | 10 | 36 | 5 | 5 | 0 |
NEK6_ENST00000545174 | NEK6 | Q9HC98 | Serine/threonine-protein kinase Nek6 | chr9 | Not Cancer Driver | No | 1 | hippie | 31 | 36 | 0 | 0 | 0 |
NEK7 | NEK7 | Q8TDX7 | Serine/threonine-protein kinase Nek7 | chr1 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 35 | 23 | 0 | 0 | 0 |
NF2 | NF2 | P35240 | Merlin | chr22 | Census, Compendium | Yes | 1 | hippie | 69 | 252 | 26 | 26 | 16 |
NFIX_ENST00000592199 | NFIX | Q14938 | Nuclear factor 1 X-type | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 60 | 305 | 40 | 40 | 6 |
NFKBIA | NFKBIA | P25963 | NF-kappa-B inhibitor alpha | chr14 | Compendium | Yes | 1 | hippie | 37 | 102 | 9 | 9 | 1 |
NGEF | NGEF | Q8N5V2 | Ephexin-1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 125 | 296 | 34 | 34 | 0 |
NIPBL | NIPBL | Q6KC79 | Nipped-B-like protein | chr5 | Compendium | Yes | 1 | hippie | 353 | 1528 | 184 | 184 | 37 |
NOTCH1 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | Census, Compendium | Yes | 1 | hippie | 363 | 686 | 87 | 87 | 3 |
NR2C2_ENST00000393102 | NR2C2 | P49116 | Nuclear receptor subfamily 2 group C member 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 62 | 186 | 24 | 24 | 0 |
NRBP2 | NRBP2 | Q9NSY0 | Nuclear receptor-binding protein 2 | chr8 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 30 | 110 | 5 | 5 | 0 |
NSD2_ENST00000382892 | NSD2 | O96028 | Histone-lysine N-methyltransferase NSD2 | chr4 | Census, Compendium | Yes | 1 | hippie | 191 | 552 | 76 | 76 | 0 |
NSMCE2_ENST00000522563 | NSMCE2 | Q96MF7 | E3 SUMO-protein ligase NSE2 | chr8 | Not Cancer Driver | No | 1 | hippie | 30 | 119 | 12 | 12 | 0 |
NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
NUF2_ENST00000367900 | NUF2 | Q9BZD4 | Kinetochore protein Nuf2 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 97 | 74 | 20 | 20 | 0 |
NUMA1 | NUMA1 | Q14980 | Nuclear mitotic apparatus protein 1 | chr11 | Census, Compendium | Yes | 1 | hippie | 234 | 1864 | 203 | 203 | 0 |
OBSL1 | OBSL1 | O75147 | Obscurin-like protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 233 | 553 | 60 | 60 | 0 |
OR5B3 | OR5B3 | Q8NH48 | Olfactory receptor 5B3 | chr11 | Not Cancer Driver | No | 1 | hippie | 104 | 0 | 0 | 0 | 0 |
OSBPL3 | OSBPL3 | Q9H4L5 | Oxysterol-binding protein-related protein 3 | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 114 | 324 | 44 | 44 | 0 |
OTUD4_ENST00000447906 | OTUD4 | Q01804 | OTU domain-containing protein 4 | chr4 | Not Cancer Driver | No | 1 | hippie | 148 | 788 | 120 | 120 | 0 |
PARP1 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 119 | 320 | 34 | 34 | 0 |
PAX6_ENST00000241001 | PAX6 | P26367 | Paired box protein Pax-6 | chr11 | Not Cancer Driver | No | 1 | hippie | 72 | 337 | 56 | 56 | 38 |
PAXIP1 | PAXIP1 | Q6ZW49 | PAX-interacting protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 120 | 461 | 39 | 39 | 0 |
PCBP1 | PCBP1 | Q15365 | Poly(rC)-binding protein 1 | chr2 | Census, Compendium | Yes | 1 | hippie | 65 | 166 | 24 | 24 | 0 |
PCNA | PCNA | P12004 | Proliferating cell nuclear antigen | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 30 | 22 | 3 | 3 | 1 |
PDCD11 | PDCD11 | Q14690 | Protein RRP5 homolog | chr10 | Not Cancer Driver | No | 1 | hippie | 212 | 487 | 64 | 64 | 0 |
PDS5A | PDS5A | Q29RF7 | Sister chromatid cohesion protein PDS5 homolog A | chr4 | Not Cancer Driver | No | 2 | hippie, biogrid | 150 | 295 | 34 | 34 | 0 |
PDS5B | PDS5B | Q9NTI5 | Sister chromatid cohesion protein PDS5 homolog B | chr13 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 174 | 455 | 61 | 61 | 0 |
PEX1 | PEX1 | O43933 | Peroxisome biogenesis factor 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 143 | 304 | 36 | 36 | 14 |
PEX3 | PEX3 | P56589 | Peroxisomal biogenesis factor 3 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 24 | 0 | 0 | 2 |
PHF1 | PHF1 | O43189 | PHD finger protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 62 | 277 | 29 | 29 | 0 |
PIH1D1 | PIH1D1 | Q9NWS0 | PIH1 domain-containing protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 30 | 157 | 13 | 13 | 0 |
PINK1 | PINK1 | Q9BXM7 | Serine/threonine-protein kinase PINK1, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie | 57 | 99 | 13 | 13 | 23 |
PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
PLK1 | PLK1 | P53350 | Serine/threonine-protein kinase PLK1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 87 | 119 | 13 | 13 | 0 |
POLA1_ENST00000379059 | POLA1 | P09884 | DNA polymerase alpha catalytic subunit | chrX | Not Cancer Driver | No | 1 | intact, hippie | 185 | 347 | 45 | 45 | 3 |
POLE | POLE | Q07864 | DNA polymerase epsilon catalytic subunit A | chr12 | Census, Compendium | Yes | 1 | hippie, biogrid | 409 | 239 | 44 | 44 | 3 |
POLR2A | POLR2A | P24928-2 | Isoform 2 of DNA-directed RNA polymerase II subunit RPB1 | chr17 | Census | Yes | 1 | hippie | 56 | 230 | 20 | 20 | 0 |
POLR2C | POLR2C | P19387 | DNA-directed RNA polymerase II subunit RPB3 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 108 | 11 | 11 | 0 |
PPIE_ENST00000324379 | PPIE | Q9UNP9 | Peptidyl-prolyl cis-trans isomerase E | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 102 | 17 | 17 | 0 |
PRKAA2 | PRKAA2 | P54646 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 128 | 98 | 26 | 26 | 0 |
PRKDC | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | Not Cancer Driver | No | 1 | hippie | 538 | 421 | 61 | 61 | 2 |
PRPF19 | PRPF19 | Q9UMS4 | Pre-mRNA-processing factor 19 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 71 | 109 | 16 | 16 | 0 |
PRPF31 | PRPF31 | Q8WWY3 | U4/U6 small nuclear ribonucleoprotein Prp31 | chr19 | Not Cancer Driver | No | 1 | hippie | 58 | 213 | 17 | 17 | 2 |
PRPF6 | PRPF6 | O94906 | Pre-mRNA-processing factor 6 | chr20 | Not Cancer Driver | No | 1 | hippie | 140 | 379 | 62 | 62 | 1 |
PRPF8 | PRPF8 | Q6P2Q9 | Pre-mRNA-processing-splicing factor 8 | chr17 | Not Cancer Driver | No | 1 | hippie | 255 | 225 | 26 | 26 | 8 |
PRR12 | PRR12 | Q9ULL5 | Proline-rich protein 12 | chr19 | Not Cancer Driver | No | 1 | hippie | 198 | 1918 | 188 | 188 | 0 |
PSD3_ENST00000440756 | PSD3 | Q9NYI0 | PH and SEC7 domain-containing protein 3 | chr8 | Not Cancer Driver | No | 1 | hippie | 146 | 645 | 94 | 94 | 0 |
PSMC2_ENST00000292644 | PSMC2 | P35998 | 26S proteasome regulatory subunit 7 | chr7 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 63 | 120 | 13 | 13 | 0 |
PTPMT1 | PTPMT1 | Q8WUK0 | Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 16 | 0 | 0 | 0 | 0 |
PTPRS | PTPRS | Q13332 | Receptor-type tyrosine-protein phosphatase S | chr19 | Not Cancer Driver | No | 1 | hippie | 250 | 829 | 111 | 111 | 0 |
RAB9A | RAB9A | P51151 | Ras-related protein Rab-9A | chrX | Not Cancer Driver | No | 1 | intact, hippie | 18 | 21 | 1 | 1 | 0 |
RAD21 | RAD21 | O60216 | Double-strand-break repair protein rad21 homolog | chr8 | Census, Compendium | Yes | 12 | intact, hippie, biogrid | 115 | 421 | 74 | 74 | 3 |
RAE1_ENST00000371242 | RAE1 | P78406 | mRNA export factor RAE1 | chr20 | Not Cancer Driver | No | 1 | hippie | 64 | 73 | 11 | 11 | 0 |
RB1CC1 | RB1CC1 | Q8TDY2 | RB1-inducible coiled-coil protein 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 202 | 578 | 75 | 75 | 0 |
RBM10_ENST00000377604 | RBM10 | P98175 | RNA-binding protein 10 | chrX | Census, Compendium | Yes | 1 | hippie | 112 | 777 | 99 | 99 | 0 |
RBM14 | RBM14 | Q96PK6 | RNA-binding protein 14 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 99 | 350 | 59 | 59 | 0 |
RBM15 | RBM15 | Q96T37 | RNA-binding protein 15 | chr1 | Census, Compendium | Yes | 1 | hippie | 118 | 686 | 91 | 91 | 0 |
REC8_ENST00000611366 | REC8 | O95072 | Meiotic recombination protein REC8 homolog | chr14 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 60 | 244 | 26 | 26 | 0 |
RFC1 | RFC1 | P35251 | Replication factor C subunit 1 | chr4 | Not Cancer Driver | No | 2 | hippie, biogrid | 147 | 674 | 82 | 82 | 0 |
RIF1 | RIF1 | Q5UIP0 | Telomere-associated protein RIF1 | chr2 | Not Cancer Driver | No | 1 | hippie | 287 | 1355 | 164 | 164 | 0 |
RIPK4_ENST00000352483 | RIPK4 | P57078 | Receptor-interacting serine/threonine-protein kinase 4 | chr21 | Not Cancer Driver | No | 1 | intact, hippie | 119 | 232 | 34 | 34 | 3 |
RNF126 | RNF126 | Q9BV68 | E3 ubiquitin-protein ligase RNF126 | chr19 | Not Cancer Driver | No | 1 | hippie | 33 | 182 | 22 | 22 | 0 |
RNF2 | RNF2 | Q99496 | E3 ubiquitin-protein ligase RING2 | chr1 | Not Cancer Driver | No | 1 | hippie | 40 | 203 | 22 | 22 | 0 |
RORA_ENST00000335670 | RORA | P35398 | Nuclear receptor ROR-alpha | chr15 | Not Cancer Driver | No | 1 | hippie | 57 | 182 | 17 | 17 | 4 |
RPA1 | RPA1 | P27694 | Replication protein A 70 kDa DNA-binding subunit | chr17 | Not Cancer Driver | No | 1 | hippie | 51 | 98 | 6 | 6 | 0 |
RPA2_ENST00000373912 | RPA2 | P15927 | Replication protein A 32 kDa subunit | chr1 | Not Cancer Driver | No | 1 | hippie | 28 | 114 | 16 | 16 | 0 |
RPA3 | RPA3 | P35244 | Replication protein A 14 kDa subunit | chr7 | Not Cancer Driver | No | 1 | hippie | 13 | 4 | 1 | 1 | 0 |
RPGR_ENST00000339363 | RPGR | Q92834 | X-linked retinitis pigmentosa GTPase regulator | chrX | Not Cancer Driver | No | 1 | hippie | 115 | 639 | 64 | 64 | 25 |
RPL11 | RPL11 | P62913 | 60S ribosomal protein L11 | chr1 | Not Cancer Driver | No | 1 | hippie | 27 | 12 | 1 | 1 | 1 |
SAP30 | SAP30 | O75446 | Histone deacetylase complex subunit SAP30 | chr4 | Not Cancer Driver | No | 1 | hippie | 26 | 123 | 17 | 17 | 0 |
SAT2 | SAT2 | Q96F10 | Thialysine N-epsilon-acetyltransferase | chr17 | Not Cancer Driver | No | 1 | hippie | 14 | 0 | 0 | 0 | 0 |
SDF4 | SDF4 | Q9BRK5 | 45 kDa calcium-binding protein | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 187 | 30 | 30 | 0 |
SF3A2 | SF3A2 | Q15428 | Splicing factor 3A subunit 2 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 382 | 21 | 21 | 0 |
SF3B1 | SF3B1 | O75533 | Splicing factor 3B subunit 1 | chr2 | Census, Compendium | Yes | 1 | hippie | 244 | 477 | 80 | 80 | 0 |
SF3B3 | SF3B3 | Q15393 | Splicing factor 3B subunit 3 | chr16 | Not Cancer Driver | No | 2 | hippie, biogrid | 154 | 145 | 19 | 19 | 0 |
SFXN1 | SFXN1 | Q9H9B4 | Sideroflexin-1 | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 31 | 29 | 1 | 1 | 0 |
SGO1 | SGO1 | Q5FBB7 | Shugoshin 1 | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 57 | 360 | 39 | 39 | 1 |
SIRT6 | SIRT6 | Q8N6T7 | NAD-dependent protein deacylase sirtuin-6 | chr19 | Not Cancer Driver | No | 1 | hippie | 33 | 164 | 12 | 12 | 0 |
SLC16A11 | SLC16A11 | Q8NCK7 | Monocarboxylate transporter 11 | chr17 | Not Cancer Driver | No | 1 | hippie | 33 | 72 | 5 | 5 | 0 |
SLFN11_ENST00000308377 | SLFN11 | Q7Z7L1 | Schlafen family member 11 | chr17 | Not Cancer Driver | No | 1 | hippie | 177 | 34 | 8 | 8 | 0 |
SMARCA5 | SMARCA5 | O60264 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 | chr4 | Not Cancer Driver | No | 1 | hippie | 116 | 363 | 48 | 48 | 0 |
SMARCAD1_ENST00000354268 | SMARCAD1 | Q9H4L7 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 129 | 388 | 50 | 50 | 0 |
SMARCB1_ENST00000644036 | SMARCB1 | Q12824 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 | chr22 | Census, Compendium | Yes | 1 | intact, hippie | 64 | 141 | 35 | 35 | 3 |
SMC1A | SMC1A | Q14683 | Structural maintenance of chromosomes protein 1A | chrX | Census, Compendium | Yes | 1 | hippie | 200 | 717 | 114 | 114 | 21 |
SMC2 | SMC2 | O95347 | Structural maintenance of chromosomes protein 2 | chr9 | Not Cancer Driver | No | 2 | hippie, biogrid | 145 | 573 | 88 | 88 | 0 |
SMC3 | SMC3 | Q9UQE7 | Structural maintenance of chromosomes protein 3 | chr10 | Not Cancer Driver | No | 14 | intact, hippie, biogrid | 149 | 605 | 70 | 70 | 0 |
SMC4_ENST00000344722 | SMC4 | Q9NTJ3 | Structural maintenance of chromosomes protein 4 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 175 | 539 | 55 | 55 | 0 |
SNAI1 | SNAI1 | O95863 | Zinc finger protein SNAI1 | chr20 | Not Cancer Driver | No | 1 | hippie | 52 | 97 | 11 | 11 | 0 |
SNRNP200 | SNRNP200 | O75643 | U5 small nuclear ribonucleoprotein 200 kDa helicase | chr2 | Not Cancer Driver | No | 1 | hippie | 237 | 270 | 37 | 37 | 11 |
SNW1_ENST00000261531 | SNW1 | Q13573 | SNW domain-containing protein 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 62 | 488 | 56 | 56 | 0 |
SNX3 | SNX3 | O60493 | Sorting nexin-3 | chr6 | Not Cancer Driver | No | 1 | hippie | 21 | 37 | 4 | 4 | 0 |
SOX2 | SOX2 | P48431 | Transcription factor SOX-2 | chr3 | Census | Yes | 2 | intact, hippie | 39 | 312 | 39 | 39 | 0 |
SP7 | SP7 | Q8TDD2 | Transcription factor Sp7 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 63 | 332 | 44 | 44 | 0 |
SPAG9 | SPAG9 | O60271 | C-Jun-amino-terminal kinase-interacting protein 4 | chr17 | Not Cancer Driver | No | 1 | hippie | 128 | 841 | 81 | 81 | 0 |
SRRM1 | SRRM1 | Q8IYB3 | Serine/arginine repetitive matrix protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 129 | 795 | 122 | 122 | 0 |
SSU72 | SSU72 | Q9NP77 | RNA polymerase II subunit A C-terminal domain phosphatase SSU72 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 18 | 65 | 3 | 3 | 0 |
STAG1 | STAG1 | Q8WVM7 | Cohesin subunit SA-1 | chr3 | Census | Yes | 6 | intact, hippie, biogrid | 226 | 391 | 66 | 66 | 8 |
STAG2_ENST00000371157 | STAG2 | Q8N3U4 | Cohesin subunit SA-2 | chrX | Census, Compendium | Yes | 9 | intact, hippie, biogrid | 179 | 330 | 46 | 46 | 3 |
STAG3_ENST00000426455 | STAG3 | Q9UJ98 | Cohesin subunit SA-3 | chr7 | Not Cancer Driver | No | 1 | hippie | 153 | 388 | 59 | 59 | 0 |
STAU1 | STAU1 | O95793 | Double-stranded RNA-binding protein Staufen homolog 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 77 | 456 | 63 | 63 | 0 |
STK38L | STK38L | Q9Y2H1 | Serine/threonine-protein kinase 38-like | chr12 | Not Cancer Driver | No | 1 | hippie | 51 | 86 | 12 | 12 | 0 |
STYXL1_ENST00000359697 | STYXL1 | Q9Y6J8 | Serine/threonine/tyrosine-interacting-like protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 55 | 18 | 3 | 3 | 0 |
SUMO1_ENST00000392245 | SUMO1 | P63165 | Small ubiquitin-related modifier 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 10 | 76 | 7 | 7 | 0 |
SUMO2 | SUMO2 | P61956 | Small ubiquitin-related modifier 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 9 | 69 | 6 | 6 | 0 |
SYCP3_ENST00000392924 | SYCP3 | Q8IZU3 | Synaptonemal complex protein 3 | chr12 | Not Cancer Driver | No | 1 | hippie | 30 | 124 | 12 | 12 | 0 |
TEAD1_ENST00000638666 | TEAD1 | P28347 | Transcriptional enhancer factor TEF-1 | chr11 | Not Cancer Driver | No | 1 | hippie | 52 | 157 | 24 | 24 | 1 |
TEAD2_ENST00000311227 | TEAD2 | Q15562 | Transcriptional enhancer factor TEF-4 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 66 | 220 | 31 | 31 | 0 |
TGFB1 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | Not Cancer Driver | No | 1 | hippie | 41 | 41 | 4 | 4 | 10 |
TGOLN2_ENST00000377386 | TGOLN2 | O43493 | Trans-Golgi network integral membrane protein 2 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 51 | 399 | 46 | 46 | 0 |
THRA | THRA | P10827 | Thyroid hormone receptor alpha | chr17 | Not Cancer Driver | No | 1 | hippie | 69 | 207 | 30 | 30 | 2 |
THRAP3_ENST00000469141 | THRAP3 | Q9Y2W1 | Thyroid hormone receptor-associated protein 3 | chr1 | Census | Yes | 1 | hippie | 137 | 955 | 137 | 137 | 0 |
THRB_ENST00000415021 | THRB | P10828 | Thyroid hormone receptor beta | chr3 | Not Cancer Driver | No | 1 | hippie | 87 | 113 | 28 | 28 | 33 |
TLX3 | TLX3 | O43711 | T-cell leukemia homeobox protein 3 | chr5 | Census | Yes | 1 | intact, hippie | 40 | 179 | 24 | 24 | 0 |
TNFRSF21 | TNFRSF21 | O75509 | Tumor necrosis factor receptor superfamily member 21 | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 98 | 280 | 46 | 46 | 0 |
TOP3B_ENST00000357179 | TOP3B | O95985 | DNA topoisomerase 3-beta-1 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 102 | 151 | 17 | 17 | 0 |
TRIM29 | TRIM29 | Q14134 | Tripartite motif-containing protein 29 | chr11 | Not Cancer Driver | No | 1 | hippie | 121 | 351 | 72 | 72 | 0 |
TRIM43 | TRIM43 | Q96BQ3 | Tripartite motif-containing protein 43 | chr2 | Not Cancer Driver | No | 1 | hippie | 48 | 28 | 7 | 7 | 0 |
TRIM72 | TRIM72 | Q6ZMU5 | Tripartite motif-containing protein 72 | chr16 | Not Cancer Driver | No | 1 | hippie | 54 | 69 | 14 | 14 | 0 |
TUBA1A | TUBA1A | Q71U36 | Tubulin alpha-1A chain | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 59 | 52 | 11 | 11 | 8 |
TUBA1B | TUBA1B | P68363 | Tubulin alpha-1B chain | chr12 | Not Cancer Driver | No | 1 | hippie | 41 | 52 | 9 | 9 | 0 |
TUBA1C_ENST00000301072 | TUBA1C | Q9BQE3 | Tubulin alpha-1C chain | chr12 | Not Cancer Driver | No | 1 | hippie | 39 | 50 | 5 | 5 | 0 |
TUBB4B | TUBB4B | P68371 | Tubulin beta-4B chain | chr9 | Not Cancer Driver | No | 1 | hippie | 52 | 65 | 11 | 11 | 2 |
TUFM | TUFM | P49411 | Elongation factor Tu, mitochondrial | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 51 | 50 | 3 | 3 | 1 |
UBR5 | UBR5 | O95071 | E3 ubiquitin-protein ligase UBR5 | chr8 | Census, Compendium | Yes | 1 | hippie | 340 | 1296 | 162 | 162 | 0 |
USP13 | USP13 | Q92995 | Ubiquitin carboxyl-terminal hydrolase 13 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 121 | 224 | 42 | 42 | 0 |
USP15 | USP15 | Q9Y4E8 | Ubiquitin carboxyl-terminal hydrolase 15 | chr12 | Not Cancer Driver | No | 1 | hippie | 136 | 259 | 39 | 39 | 0 |
USP32 | USP32 | Q8NFA0 | Ubiquitin carboxyl-terminal hydrolase 32 | chr17 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 182 | 401 | 43 | 43 | 0 |
USP37_ENST00000454775 | USP37 | Q86T82 | Ubiquitin carboxyl-terminal hydrolase 37 | chr2 | Not Cancer Driver | No | 1 | hippie | 112 | 530 | 62 | 62 | 0 |
VIRMA | VIRMA | Q69YN4 | Protein virilizer homolog | chr8 | Not Cancer Driver | No | 1 | hippie | 211 | 631 | 93 | 93 | 0 |
VPS33A | VPS33A | Q96AX1 | Vacuolar protein sorting-associated protein 33A | chr12 | Not Cancer Driver | No | 1 | hippie | 73 | 46 | 8 | 8 | 1 |
VSIG4 | VSIG4 | Q9Y279 | V-set and immunoglobulin domain-containing protein 4 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 73 | 70 | 13 | 13 | 0 |
WAPL_ENST00000618527 | WAPL | Q7Z5K2 | Wings apart-like protein homolog | chr10 | Not Cancer Driver | No | 5 | intact, hippie | 140 | 621 | 68 | 68 | 0 |
WDR76 | WDR76 | Q9H967 | WD repeat-containing protein 76 | chr15 | Not Cancer Driver | No | 1 | hippie | 60 | 288 | 33 | 33 | 0 |
WFDC5_ENST00000307971 | WFDC5 | Q8TCV5 | WAP four-disulfide core domain protein 5 | chr20 | Not Cancer Driver | No | 1 | hippie | 42 | 22 | 2 | 2 | 0 |
WNK2 | WNK2 | Q9Y3S1 | Serine/threonine-protein kinase WNK2 | chr9 | Census, Compendium | Yes | 1 | hippie | 223 | 1868 | 167 | 167 | 0 |
WWP2 | WWP2 | O00308 | NEDD4-like E3 ubiquitin-protein ligase WWP2 | chr16 | Not Cancer Driver | No | 1 | hippie | 112 | 422 | 57 | 57 | 0 |
YWHAZ_ENST00000395956 | YWHAZ | P63104 | 14-3-3 protein zeta/delta | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 30 | 81 | 10 | 10 | 0 |
YY1 | YY1 | P25490 | Transcriptional repressor protein YY1 | chr14 | Not Cancer Driver | No | 1 | hippie | 37 | 336 | 26 | 26 | 2 |
ZBTB7A_ENST00000601588 | ZBTB7A | O95365 | Zinc finger and BTB domain-containing protein 7A | chr19 | Not Cancer Driver | No | 1 | hippie | 60 | 285 | 30 | 30 | 0 |
ZC3H18_ENST00000301011 | ZC3H18 | Q86VM9 | Zinc finger CCCH domain-containing protein 18 | chr16 | Not Cancer Driver | No | 1 | hippie | 139 | 929 | 134 | 134 | 0 |
ZDHHC5 | ZDHHC5 | Q9C0B5 | Palmitoyltransferase ZDHHC5 | chr11 | Not Cancer Driver | No | 1 | hippie | 89 | 462 | 63 | 63 | 0 |
ZNF174_ENST00000571936 | ZNF174 | Q15697 | Zinc finger protein 174 | chr16 | Not Cancer Driver | No | 1 | hippie | 51 | 274 | 38 | 38 | 0 |
ZNF608 | ZNF608 | Q9ULD9 | Zinc finger protein 608 | chr5 | Not Cancer Driver | No | 1 | hippie | 170 | 1433 | 162 | 162 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
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