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SLC9A1 ,SLC9A1 ,P19634
  • Uniprot Accession= P19634
  • Ensembl Transcript= ENST00000263980.7
  • Uniprot Name= SLC9A1
  • Name= Sodium/hydrogen exchanger 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 66
  • Number of Interaction partner in hippie: 111
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 1 hippie 108 158 24 24 4
ANPEP ANPEP P15144 Aminopeptidase N chr15 Not Cancer Driver No 1 hippie, biogrid 175 109 26 26 0
AOC3 AOC3 Q16853 Membrane primary amine oxidase chr17 Not Cancer Driver No 2 hippie, biogrid 112 101 13 13 0
AP4S1_ENST00000616371 AP4S1 Q9Y587 AP-4 complex subunit sigma-1 chr14 Not Cancer Driver No 1 hippie 11 0 0 0 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie 34 103 14 14 0
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie, biogrid 18 5 0 0 0
ARRB1 ARRB1 P49407 Beta-arrestin-1 chr11 Not Cancer Driver No 1 hippie 49 154 13 13 0
ATP2A1 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 Not Cancer Driver No 1 hippie, biogrid 157 80 11 11 1
B3GAT1_ENST00000312527 B3GAT1 Q9P2W7 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 chr11 Not Cancer Driver No 1 hippie, biogrid 85 93 32 32 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX Not Cancer Driver No 1 hippie, biogrid 37 104 14 14 0
C1orf210_ENST00000423420 C1orf210 Q8IVY1 Type III endosome membrane protein TEMP chr1 Not Cancer Driver No 1 hippie, biogrid 20 74 16 16 0
CA2 CA2 P00918 Carbonic anhydrase 2 chr8 Not Cancer Driver No 1 hippie 41 55 8 8 4
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 Not Cancer Driver No 1 hippie 19 115 15 15 7
CCDC107 CCDC107 Q8WV48 Coiled-coil domain-containing protein 107 chr9 Not Cancer Driver No 2 hippie, biogrid 14 215 12 12 0
CCR6_ENST00000349984 CCR6 P51684 C-C chemokine receptor type 6 chr6 Not Cancer Driver No 1 hippie, biogrid 56 13 2 2 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
CHP1 CHP1 Q99653 Calcineurin B homologous protein 1 chr15 Not Cancer Driver No 1 hippie 27 70 12 12 0
CHP2 CHP2 O43745 Calcineurin B homologous protein 2 chr16 Not Cancer Driver No 2 hippie, biogrid 43 65 16 16 0
COA3 COA3 Q9Y2R0 Cytochrome c oxidase assembly factor 3 homolog, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 4 57 3 3 0
CRLF2_ENST00000381566 CRLF2 Q9HC73 Cytokine receptor-like factor 2 chrX Census Yes 1 hippie, biogrid 54 62 3 3 0
CX3CL1 CX3CL1 P78423 Fractalkine chr16 Not Cancer Driver No 1 hippie, biogrid 66 259 44 44 0
DAXX_ENST00000266000 DAXX Q9UER7 Death domain-associated protein 6 chr6 Census, Compendium Yes 1 hippie 106 549 81 81 0
DGCR2 DGCR2 P98153 Integral membrane protein DGCR2/IDD chr22 Not Cancer Driver No 1 hippie, biogrid 90 178 24 24 0
DIRAS3_ENST00000646789 DIRAS3 O95661 GTP-binding protein Di-Ras3 chr1 Not Cancer Driver No 1 hippie, biogrid 38 21 3 3 0
EMD EMD P50402 Emerin chrX Not Cancer Driver No 1 hippie, biogrid 42 160 28 28 4
ENO1 ENO1 P06733 Alpha-enolase chr1 Not Cancer Driver No 1 hippie 51 21 2 2 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
FAM189A2 FAM189A2 Q15884 Protein FAM189A2 chr9 Not Cancer Driver No 2 hippie, biogrid 62 231 29 29 0
FAXC FAXC Q5TGI0 Failed axon connections homolog chr6 Not Cancer Driver No 1 hippie, biogrid 47 54 11 11 0
FNDC5_ENST00000640867 FNDC5 Q8NAU1 Fibronectin type III domain-containing protein 5 chr1 Not Cancer Driver No 2 hippie, biogrid 17 74 8 8 0
FUT1_ENST00000645652 FUT1 P19526 Galactoside alpha-(1,2)-fucosyltransferase 1 chr19 Not Cancer Driver No 2 hippie, biogrid 63 17 3 3 0
GALNT6_ENST00000356317 GALNT6 Q8NCL4 Polypeptide N-acetylgalactosaminyltransferase 6 chr12 Not Cancer Driver No 1 hippie, biogrid 105 117 26 26 0
GALNT7 GALNT7 Q86SF2 N-acetylgalactosaminyltransferase 7 chr4 Not Cancer Driver No 2 hippie, biogrid 78 117 17 17 0
GJD3 GJD3 Q8N144 Gap junction delta-3 protein chr17 Not Cancer Driver No 1 hippie, biogrid 5 79 0 0 0
GPR151 GPR151 Q8TDV0 G-protein coupled receptor 151 chr5 Not Cancer Driver No 1 hippie, biogrid 51 97 13 13 0
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie 107 16 4 4 18
HSD17B11 HSD17B11 Q8NBQ5 Estradiol 17-beta-dehydrogenase 11 chr4 Not Cancer Driver No 1 hippie, biogrid 28 3 0 0 0
HSD3B7 HSD3B7 Q9H2F3 3 beta-hydroxysteroid dehydrogenase type 7 chr16 Not Cancer Driver No 1 hippie, biogrid 43 27 5 5 2
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 hippie 106 257 37 37 0
HSPA4 HSPA4 P34932 Heat shock 70 kDa protein 4 chr5 Not Cancer Driver No 1 hippie 80 351 24 24 0
HTR3B HTR3B O95264 5-hydroxytryptamine receptor 3B chr11 Not Cancer Driver No 1 hippie, biogrid 91 8 0 0 0
IGF2R IGF2R P11717 Cation-independent mannose-6-phosphate receptor chr6 Not Cancer Driver No 1 hippie, biogrid 318 255 20 20 0
IL2RA IL2RA P01589 Interleukin-2 receptor subunit alpha chr10 Not Cancer Driver No 1 hippie, biogrid 51 131 29 29 2
IPPK IPPK Q9H8X2 Inositol-pentakisphosphate 2-kinase chr9 Not Cancer Driver No 2 hippie, biogrid 55 43 3 3 0
KCNE3 KCNE3 Q9Y6H6 Potassium voltage-gated channel subfamily E member 3 chr11 Not Cancer Driver No 1 hippie, biogrid 28 24 2 2 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 2 hippie, biogrid 788 7 2 2 27
LAMP3 LAMP3 Q9UQV4 Lysosome-associated membrane glycoprotein 3 chr3 Not Cancer Driver No 1 hippie, biogrid 67 222 38 38 0
LHFPL4 LHFPL4 Q7Z7J7 LHFPL tetraspan subfamily member 4 protein chr3 Not Cancer Driver No 1 hippie, biogrid 53 0 0 0 0
LMAN1 LMAN1 P49257 Protein ERGIC-53 chr18 Not Cancer Driver No 1 hippie, biogrid 63 222 25 25 1
LPAR1_ENST00000358883 LPAR1 Q92633 Lysophosphatidic acid receptor 1 chr9 Not Cancer Driver No 3 hippie, biogrid 79 21 6 6 0
LRRC55 LRRC55 A0A494C0H1 Leucine-rich repeat-containing protein 55 chr11 Not Cancer Driver No 1 hippie, biogrid 90 3 1 1 0
LYPD3 LYPD3 O95274 Ly6/PLAUR domain-containing protein 3 chr19 Not Cancer Driver No 3 hippie, biogrid 52 116 15 15 0
MAP3K14 MAP3K14 Q99558 Mitogen-activated protein kinase kinase kinase 14 chr17 Not Cancer Driver No 1 hippie 94 543 52 52 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 Not Cancer Driver No 1 hippie 104 333 66 66 6
MAP4K4_ENST00000347699 MAP4K4 O95819 Mitogen-activated protein kinase kinase kinase kinase 4 chr2 Not Cancer Driver No 1 hippie 143 649 55 55 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 Not Cancer Driver No 1 hippie 39 25 1 1 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 hippie 62 2 0 0 7
MDFI MDFI Q99750 MyoD family inhibitor chr6 Not Cancer Driver No 1 hippie 25 152 15 15 0
METTL7A_ENST00000332160 METTL7A Q9H8H3 Putative methyltransferase-like protein 7A chr12 Not Cancer Driver No 1 hippie, biogrid 31 0 0 0 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 Not Cancer Driver No 1 hippie 150 711 79 79 0
NRAS NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 284 10 0 0 14
OPRL1_ENST00000336866 OPRL1 P41146 Nociceptin receptor chr20 Not Cancer Driver No 1 hippie, biogrid 81 0 0 0 0
OTULINL OTULINL Q9NUU6 Inactive ubiquitin thioesterase OTULINL chr5 Not Cancer Driver No 1 hippie 59 21 0 0 0
PANX1 PANX1 Q96RD7 Pannexin-1 chr11 Not Cancer Driver No 1 hippie, biogrid 54 45 7 7 2
PTGER3_ENST00000370931 PTGER3 P43115 Prostaglandin E2 receptor EP3 subtype chr1 Not Cancer Driver No 3 hippie, biogrid 79 17 2 2 0
PTGFRN PTGFRN Q9P2B2 Prostaglandin F2 receptor negative regulator chr1 Not Cancer Driver No 1 hippie, biogrid 122 121 16 16 0
PTGIR PTGIR P43119 Prostacyclin receptor chr19 Not Cancer Driver No 2 hippie, biogrid 40 47 4 4 0
RAB2A RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie, biogrid 22 58 4 4 0
RAB35 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie, biogrid 25 25 2 2 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 66 2 1 1 6
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 Not Cancer Driver No 1 hippie 31 0 0 0 2
RAC3 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 Not Cancer Driver No 1 hippie 24 0 0 0 4
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 2 hippie, biogrid 52 19 2 2 0
RHOC_ENST00000369642 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 Not Cancer Driver No 1 hippie 30 53 7 7 0
RHOD RHOD O00212 Rho-related GTP-binding protein RhoD chr11 Not Cancer Driver No 1 hippie 20 10 0 0 0
RHOF RHOF Q9HBH0 Rho-related GTP-binding protein RhoF chr12 Not Cancer Driver No 1 hippie 18 10 0 0 0
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 26 22 5 5 0
RHOH_ENST00000617441 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 Census Yes 1 hippie 41 12 3 3 0
RHOJ RHOJ Q9H4E5 Rho-related GTP-binding protein RhoJ chr14 Not Cancer Driver No 1 hippie 39 0 0 0 0
RHOQ RHOQ P17081 Rho-related GTP-binding protein RhoQ chr2 Not Cancer Driver No 1 hippie 25 0 0 0 0
RND2 RND2 P52198 Rho-related GTP-binding protein RhoN chr17 Not Cancer Driver No 1 hippie 19 54 4 4 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 Not Cancer Driver No 1 hippie 184 780 103 103 0
RPN1 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 2 hippie, biogrid 50 69 3 3 0
RPN2 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 hippie, biogrid 53 26 4 4 0
RPS6KA6_ENST00000262752 RPS6KA6 Q9UK32 Ribosomal protein S6 kinase alpha-6 chrX Not Cancer Driver No 1 hippie, biogrid 180 136 36 36 0
SEC61B SEC61B P60468 Protein transport protein Sec61 subunit beta chr9 Not Cancer Driver No 1 hippie, biogrid 11 60 7 7 0
SEC62 SEC62 Q99442 Translocation protein SEC62 chr3 Not Cancer Driver No 1 hippie, biogrid 41 211 23 23 0
SEMA7A SEMA7A O75326 Semaphorin-7A chr15 Not Cancer Driver No 2 hippie, biogrid 81 150 21 21 0
SLC20A1 SLC20A1 Q8WUM9 Sodium-dependent phosphate transporter 1 chr2 Not Cancer Driver No 1 hippie, biogrid 67 157 9 9 0
SLC22A2 SLC22A2 O15244 Solute carrier family 22 member 2 chr6 Not Cancer Driver No 1 hippie, biogrid 126 31 11 11 0
SLCO4C1 SLCO4C1 Q6ZQN7 Solute carrier organic anion transporter family member 4C1 chr5 Not Cancer Driver No 1 hippie, biogrid 129 86 10 10 0
SLCO6A1_ENST00000379807 SLCO6A1 Q86UG4 Solute carrier organic anion transporter family member 6A1 chr5 Not Cancer Driver No 2 hippie, biogrid 224 67 38 38 0
ST7 ST7 Q9NRC1 Suppressor of tumorigenicity 7 protein chr7 Not Cancer Driver No 1 hippie 62 64 5 5 0
STRA6_ENST00000323940 STRA6 Q9BX79 Receptor for retinol uptake STRA6 chr15 Not Cancer Driver No 1 hippie, biogrid 77 84 14 14 6
STX4 STX4 Q12846 Syntaxin-4 chr16 Not Cancer Driver No 1 hippie, biogrid 50 152 20 20 0
STX7 STX7 O15400 Syntaxin-7 chr6 Not Cancer Driver No 1 hippie, biogrid 29 164 14 14 0
TCTN2 TCTN2 Q96GX1 Tectonic-2 chr12 Not Cancer Driver No 2 hippie, biogrid 75 23 2 2 0
TCTN3 TCTN3 Q6NUS6 Tectonic-3 chr10 Not Cancer Driver No 1 hippie 45 71 8 8 1
TESC TESC Q96BS2 Calcineurin B homologous protein 3 chr12 Not Cancer Driver No 1 hippie 31 73 6 6 0
TMEM17 TMEM17 Q86X19 Transmembrane protein 17 chr2 Not Cancer Driver No 1 hippie 22 14 2 2 0
TMPRSS11B TMPRSS11B Q86T26 Transmembrane protease serine 11B chr4 Not Cancer Driver No 1 hippie, biogrid 95 5 0 0 0
TMPRSS4_ENST00000437212 TMPRSS4 Q9NRS4 Transmembrane protease serine 4 chr11 Not Cancer Driver No 1 hippie, biogrid 47 35 4 4 0
TNIK TNIK Q9UKE5 TRAF2 and NCK-interacting protein kinase chr3 Not Cancer Driver No 1 hippie 254 781 156 156 0
TTYH1_ENST00000376530 TTYH1 Q9H313 Protein tweety homolog 1 chr19 Not Cancer Driver No 1 hippie, biogrid 56 21 3 3 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 Not Cancer Driver No 1 hippie 16 16 3 3 0
WNK1_ENST00000315939 WNK1 Q9H4A3 Serine/threonine-protein kinase WNK1 chr12 Not Cancer Driver No 1 hippie 278 1959 223 223 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 1 hippie 22 109 4 4 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 1 hippie 30 81 10 10 0
ZFPL1 ZFPL1 O95159 Zinc finger protein-like 1 chr11 Not Cancer Driver No 1 hippie, biogrid 40 127 16 16 0