Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | Census, Compendium | Yes | 1 | hippie | 108 | 158 | 24 | 24 | 4 |
ANPEP | ANPEP | P15144 | Aminopeptidase N | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 175 | 109 | 26 | 26 | 0 |
AOC3 | AOC3 | Q16853 | Membrane primary amine oxidase | chr17 | Not Cancer Driver | No | 2 | hippie, biogrid | 112 | 101 | 13 | 13 | 0 |
AP4S1_ENST00000616371 | AP4S1 | Q9Y587 | AP-4 complex subunit sigma-1 | chr14 | Not Cancer Driver | No | 1 | hippie | 11 | 0 | 0 | 0 | 0 |
APEX1_ENST00000555414 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | Not Cancer Driver | No | 1 | hippie | 34 | 103 | 14 | 14 | 0 |
ARF6 | ARF6 | P62330 | ADP-ribosylation factor 6 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 5 | 0 | 0 | 0 |
ARRB1 | ARRB1 | P49407 | Beta-arrestin-1 | chr11 | Not Cancer Driver | No | 1 | hippie | 49 | 154 | 13 | 13 | 0 |
ATP2A1 | ATP2A1 | O14983 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 157 | 80 | 11 | 11 | 1 |
B3GAT1_ENST00000312527 | B3GAT1 | Q9P2W7 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 85 | 93 | 32 | 32 | 0 |
BCAP31_ENST00000345046 | BCAP31 | P51572 | B-cell receptor-associated protein 31 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 104 | 14 | 14 | 0 |
C1orf210_ENST00000423420 | C1orf210 | Q8IVY1 | Type III endosome membrane protein TEMP | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 74 | 16 | 16 | 0 |
CA2 | CA2 | P00918 | Carbonic anhydrase 2 | chr8 | Not Cancer Driver | No | 1 | hippie | 41 | 55 | 8 | 8 | 4 |
CALM1 | CALM1 | P0DP23 | Calmodulin-1 | chr14 | Not Cancer Driver | No | 1 | hippie | 19 | 115 | 15 | 15 | 7 |
CCDC107 | CCDC107 | Q8WV48 | Coiled-coil domain-containing protein 107 | chr9 | Not Cancer Driver | No | 2 | hippie, biogrid | 14 | 215 | 12 | 12 | 0 |
CCR6_ENST00000349984 | CCR6 | P51684 | C-C chemokine receptor type 6 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 13 | 2 | 2 | 0 |
CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 39 | 23 | 2 | 2 | 1 |
CDH1 | CDH1 | P12830 | Cadherin-1 | chr16 | Census, Compendium | Yes | 1 | hippie | 150 | 400 | 82 | 82 | 5 |
CHP1 | CHP1 | Q99653 | Calcineurin B homologous protein 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 27 | 70 | 12 | 12 | 0 |
CHP2 | CHP2 | O43745 | Calcineurin B homologous protein 2 | chr16 | Not Cancer Driver | No | 2 | hippie, biogrid | 43 | 65 | 16 | 16 | 0 |
COA3 | COA3 | Q9Y2R0 | Cytochrome c oxidase assembly factor 3 homolog, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 4 | 57 | 3 | 3 | 0 |
CRLF2_ENST00000381566 | CRLF2 | Q9HC73 | Cytokine receptor-like factor 2 | chrX | Census | Yes | 1 | hippie, biogrid | 54 | 62 | 3 | 3 | 0 |
CX3CL1 | CX3CL1 | P78423 | Fractalkine | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 66 | 259 | 44 | 44 | 0 |
DAXX_ENST00000266000 | DAXX | Q9UER7 | Death domain-associated protein 6 | chr6 | Census, Compendium | Yes | 1 | hippie | 106 | 549 | 81 | 81 | 0 |
DGCR2 | DGCR2 | P98153 | Integral membrane protein DGCR2/IDD | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 90 | 178 | 24 | 24 | 0 |
DIRAS3_ENST00000646789 | DIRAS3 | O95661 | GTP-binding protein Di-Ras3 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 21 | 3 | 3 | 0 |
EMD | EMD | P50402 | Emerin | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 160 | 28 | 28 | 4 |
ENO1 | ENO1 | P06733 | Alpha-enolase | chr1 | Not Cancer Driver | No | 1 | hippie | 51 | 21 | 2 | 2 | 0 |
ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | hippie | 121 | 195 | 27 | 27 | 2 |
FAM189A2 | FAM189A2 | Q15884 | Protein FAM189A2 | chr9 | Not Cancer Driver | No | 2 | hippie, biogrid | 62 | 231 | 29 | 29 | 0 |
FAXC | FAXC | Q5TGI0 | Failed axon connections homolog | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 54 | 11 | 11 | 0 |
FNDC5_ENST00000640867 | FNDC5 | Q8NAU1 | Fibronectin type III domain-containing protein 5 | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 17 | 74 | 8 | 8 | 0 |
FUT1_ENST00000645652 | FUT1 | P19526 | Galactoside alpha-(1,2)-fucosyltransferase 1 | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 63 | 17 | 3 | 3 | 0 |
GALNT6_ENST00000356317 | GALNT6 | Q8NCL4 | Polypeptide N-acetylgalactosaminyltransferase 6 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 105 | 117 | 26 | 26 | 0 |
GALNT7 | GALNT7 | Q86SF2 | N-acetylgalactosaminyltransferase 7 | chr4 | Not Cancer Driver | No | 2 | hippie, biogrid | 78 | 117 | 17 | 17 | 0 |
GJD3 | GJD3 | Q8N144 | Gap junction delta-3 protein | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 5 | 79 | 0 | 0 | 0 |
GPR151 | GPR151 | Q8TDV0 | G-protein coupled receptor 151 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 97 | 13 | 13 | 0 |
HRAS | HRAS | P01112 | GTPase HRas | chr11 | Census, Compendium | Yes | 1 | hippie | 107 | 16 | 4 | 4 | 18 |
HSD17B11 | HSD17B11 | Q8NBQ5 | Estradiol 17-beta-dehydrogenase 11 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 3 | 0 | 0 | 0 |
HSD3B7 | HSD3B7 | Q9H2F3 | 3 beta-hydroxysteroid dehydrogenase type 7 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 27 | 5 | 5 | 2 |
HSP90AA1_ENST00000216281 | HSP90AA1 | P07900 | Heat shock protein HSP 90-alpha | chr14 | Census, Compendium | Yes | 1 | hippie | 106 | 257 | 37 | 37 | 0 |
HSPA4 | HSPA4 | P34932 | Heat shock 70 kDa protein 4 | chr5 | Not Cancer Driver | No | 1 | hippie | 80 | 351 | 24 | 24 | 0 |
HTR3B | HTR3B | O95264 | 5-hydroxytryptamine receptor 3B | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 91 | 8 | 0 | 0 | 0 |
IGF2R | IGF2R | P11717 | Cation-independent mannose-6-phosphate receptor | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 318 | 255 | 20 | 20 | 0 |
IL2RA | IL2RA | P01589 | Interleukin-2 receptor subunit alpha | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 131 | 29 | 29 | 2 |
IPPK | IPPK | Q9H8X2 | Inositol-pentakisphosphate 2-kinase | chr9 | Not Cancer Driver | No | 2 | hippie, biogrid | 55 | 43 | 3 | 3 | 0 |
KCNE3 | KCNE3 | Q9Y6H6 | Potassium voltage-gated channel subfamily E member 3 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 24 | 2 | 2 | 0 |
KRAS | KRAS | P01116 | GTPase KRas | chr12 | Census, Compendium | Yes | 2 | hippie, biogrid | 788 | 7 | 2 | 2 | 27 |
LAMP3 | LAMP3 | Q9UQV4 | Lysosome-associated membrane glycoprotein 3 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 222 | 38 | 38 | 0 |
LHFPL4 | LHFPL4 | Q7Z7J7 | LHFPL tetraspan subfamily member 4 protein | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 0 | 0 | 0 | 0 |
LMAN1 | LMAN1 | P49257 | Protein ERGIC-53 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 222 | 25 | 25 | 1 |
LPAR1_ENST00000358883 | LPAR1 | Q92633 | Lysophosphatidic acid receptor 1 | chr9 | Not Cancer Driver | No | 3 | hippie, biogrid | 79 | 21 | 6 | 6 | 0 |
LRRC55 | LRRC55 | A0A494C0H1 | Leucine-rich repeat-containing protein 55 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 90 | 3 | 1 | 1 | 0 |
LYPD3 | LYPD3 | O95274 | Ly6/PLAUR domain-containing protein 3 | chr19 | Not Cancer Driver | No | 3 | hippie, biogrid | 52 | 116 | 15 | 15 | 0 |
MAP3K14 | MAP3K14 | Q99558 | Mitogen-activated protein kinase kinase kinase 14 | chr17 | Not Cancer Driver | No | 1 | hippie | 94 | 543 | 52 | 52 | 0 |
MAP3K7 | MAP3K7 | O43318 | Mitogen-activated protein kinase kinase kinase 7 | chr6 | Not Cancer Driver | No | 1 | hippie | 104 | 333 | 66 | 66 | 6 |
MAP4K4_ENST00000347699 | MAP4K4 | O95819 | Mitogen-activated protein kinase kinase kinase kinase 4 | chr2 | Not Cancer Driver | No | 1 | hippie | 143 | 649 | 55 | 55 | 0 |
MAPK14_ENST00000229794 | MAPK14 | Q16539 | Mitogen-activated protein kinase 14 | chr6 | Not Cancer Driver | No | 1 | hippie | 39 | 25 | 1 | 1 | 0 |
MAPK1_ENST00000398822 | MAPK1 | P28482 | Mitogen-activated protein kinase 1 | chr22 | Census, Compendium | Yes | 1 | hippie | 62 | 2 | 0 | 0 | 7 |
MDFI | MDFI | Q99750 | MyoD family inhibitor | chr6 | Not Cancer Driver | No | 1 | hippie | 25 | 152 | 15 | 15 | 0 |
METTL7A_ENST00000332160 | METTL7A | Q9H8H3 | Putative methyltransferase-like protein 7A | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 0 | 0 | 0 | 0 |
NEDD4 | NEDD4 | P46934 | E3 ubiquitin-protein ligase NEDD4 | chr15 | Not Cancer Driver | No | 1 | hippie | 150 | 711 | 79 | 79 | 0 |
NRAS | NRAS | P01111 | GTPase NRas | chr1 | Census, Compendium | Yes | 1 | hippie, biogrid | 284 | 10 | 0 | 0 | 14 |
OPRL1_ENST00000336866 | OPRL1 | P41146 | Nociceptin receptor | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 0 | 0 | 0 | 0 |
OTULINL | OTULINL | Q9NUU6 | Inactive ubiquitin thioesterase OTULINL | chr5 | Not Cancer Driver | No | 1 | hippie | 59 | 21 | 0 | 0 | 0 |
PANX1 | PANX1 | Q96RD7 | Pannexin-1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 45 | 7 | 7 | 2 |
PTGER3_ENST00000370931 | PTGER3 | P43115 | Prostaglandin E2 receptor EP3 subtype | chr1 | Not Cancer Driver | No | 3 | hippie, biogrid | 79 | 17 | 2 | 2 | 0 |
PTGFRN | PTGFRN | Q9P2B2 | Prostaglandin F2 receptor negative regulator | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 122 | 121 | 16 | 16 | 0 |
PTGIR | PTGIR | P43119 | Prostacyclin receptor | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 40 | 47 | 4 | 4 | 0 |
RAB2A | RAB2A | P61019 | Ras-related protein Rab-2A | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 58 | 4 | 4 | 0 |
RAB35 | RAB35 | Q15286 | Ras-related protein Rab-35 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 25 | 2 | 2 | 0 |
RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | Census, Compendium | Yes | 1 | hippie | 66 | 2 | 1 | 1 | 6 |
RAC2 | RAC2 | P15153 | Ras-related C3 botulinum toxin substrate 2 | chr22 | Not Cancer Driver | No | 1 | hippie | 31 | 0 | 0 | 0 | 2 |
RAC3 | RAC3 | P60763 | Ras-related C3 botulinum toxin substrate 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 4 |
RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | Census, Compendium | Yes | 1 | hippie | 99 | 46 | 13 | 13 | 2 |
RHOB | RHOB | P62745 | Rho-related GTP-binding protein RhoB | chr2 | Not Cancer Driver | No | 2 | hippie, biogrid | 52 | 19 | 2 | 2 | 0 |
RHOC_ENST00000369642 | RHOC | P08134 | Rho-related GTP-binding protein RhoC | chr1 | Not Cancer Driver | No | 1 | hippie | 30 | 53 | 7 | 7 | 0 |
RHOD | RHOD | O00212 | Rho-related GTP-binding protein RhoD | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 10 | 0 | 0 | 0 |
RHOF | RHOF | Q9HBH0 | Rho-related GTP-binding protein RhoF | chr12 | Not Cancer Driver | No | 1 | hippie | 18 | 10 | 0 | 0 | 0 |
RHOG_ENST00000396978 | RHOG | P84095 | Rho-related GTP-binding protein RhoG | chr11 | Not Cancer Driver | No | 1 | hippie | 26 | 22 | 5 | 5 | 0 |
RHOH_ENST00000617441 | RHOH | Q15669 | Rho-related GTP-binding protein RhoH | chr4 | Census | Yes | 1 | hippie | 41 | 12 | 3 | 3 | 0 |
RHOJ | RHOJ | Q9H4E5 | Rho-related GTP-binding protein RhoJ | chr14 | Not Cancer Driver | No | 1 | hippie | 39 | 0 | 0 | 0 | 0 |
RHOQ | RHOQ | P17081 | Rho-related GTP-binding protein RhoQ | chr2 | Not Cancer Driver | No | 1 | hippie | 25 | 0 | 0 | 0 | 0 |
RND2 | RND2 | P52198 | Rho-related GTP-binding protein RhoN | chr17 | Not Cancer Driver | No | 1 | hippie | 19 | 54 | 4 | 4 | 0 |
ROCK1 | ROCK1 | Q13464 | Rho-associated protein kinase 1 | chr18 | Not Cancer Driver | No | 1 | hippie | 184 | 780 | 103 | 103 | 0 |
RPN1 | RPN1 | P04843 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 | chr3 | Census | Yes | 2 | hippie, biogrid | 50 | 69 | 3 | 3 | 0 |
RPN2 | RPN2 | P04844 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 26 | 4 | 4 | 0 |
RPS6KA6_ENST00000262752 | RPS6KA6 | Q9UK32 | Ribosomal protein S6 kinase alpha-6 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 180 | 136 | 36 | 36 | 0 |
SEC61B | SEC61B | P60468 | Protein transport protein Sec61 subunit beta | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 60 | 7 | 7 | 0 |
SEC62 | SEC62 | Q99442 | Translocation protein SEC62 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 211 | 23 | 23 | 0 |
SEMA7A | SEMA7A | O75326 | Semaphorin-7A | chr15 | Not Cancer Driver | No | 2 | hippie, biogrid | 81 | 150 | 21 | 21 | 0 |
SLC20A1 | SLC20A1 | Q8WUM9 | Sodium-dependent phosphate transporter 1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 157 | 9 | 9 | 0 |
SLC22A2 | SLC22A2 | O15244 | Solute carrier family 22 member 2 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 126 | 31 | 11 | 11 | 0 |
SLCO4C1 | SLCO4C1 | Q6ZQN7 | Solute carrier organic anion transporter family member 4C1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 129 | 86 | 10 | 10 | 0 |
SLCO6A1_ENST00000379807 | SLCO6A1 | Q86UG4 | Solute carrier organic anion transporter family member 6A1 | chr5 | Not Cancer Driver | No | 2 | hippie, biogrid | 224 | 67 | 38 | 38 | 0 |
ST7 | ST7 | Q9NRC1 | Suppressor of tumorigenicity 7 protein | chr7 | Not Cancer Driver | No | 1 | hippie | 62 | 64 | 5 | 5 | 0 |
STRA6_ENST00000323940 | STRA6 | Q9BX79 | Receptor for retinol uptake STRA6 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 77 | 84 | 14 | 14 | 6 |
STX4 | STX4 | Q12846 | Syntaxin-4 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 152 | 20 | 20 | 0 |
STX7 | STX7 | O15400 | Syntaxin-7 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 164 | 14 | 14 | 0 |
TCTN2 | TCTN2 | Q96GX1 | Tectonic-2 | chr12 | Not Cancer Driver | No | 2 | hippie, biogrid | 75 | 23 | 2 | 2 | 0 |
TCTN3 | TCTN3 | Q6NUS6 | Tectonic-3 | chr10 | Not Cancer Driver | No | 1 | hippie | 45 | 71 | 8 | 8 | 1 |
TESC | TESC | Q96BS2 | Calcineurin B homologous protein 3 | chr12 | Not Cancer Driver | No | 1 | hippie | 31 | 73 | 6 | 6 | 0 |
TMEM17 | TMEM17 | Q86X19 | Transmembrane protein 17 | chr2 | Not Cancer Driver | No | 1 | hippie | 22 | 14 | 2 | 2 | 0 |
TMPRSS11B | TMPRSS11B | Q86T26 | Transmembrane protease serine 11B | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 95 | 5 | 0 | 0 | 0 |
TMPRSS4_ENST00000437212 | TMPRSS4 | Q9NRS4 | Transmembrane protease serine 4 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 35 | 4 | 4 | 0 |
TNIK | TNIK | Q9UKE5 | TRAF2 and NCK-interacting protein kinase | chr3 | Not Cancer Driver | No | 1 | hippie | 254 | 781 | 156 | 156 | 0 |
TTYH1_ENST00000376530 | TTYH1 | Q9H313 | Protein tweety homolog 1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 21 | 3 | 3 | 0 |
UBE2I | UBE2I | P63279 | SUMO-conjugating enzyme UBC9 | chr16 | Not Cancer Driver | No | 1 | hippie | 16 | 16 | 3 | 3 | 0 |
WNK1_ENST00000315939 | WNK1 | Q9H4A3 | Serine/threonine-protein kinase WNK1 | chr12 | Not Cancer Driver | No | 1 | hippie | 278 | 1959 | 223 | 223 | 0 |
YWHAB_ENST00000353703 | YWHAB | P31946 | 14-3-3 protein beta/alpha | chr20 | Not Cancer Driver | No | 1 | hippie | 22 | 109 | 4 | 4 | 0 |
YWHAZ_ENST00000395956 | YWHAZ | P63104 | 14-3-3 protein zeta/delta | chr8 | Not Cancer Driver | No | 1 | hippie | 30 | 81 | 10 | 10 | 0 |
ZFPL1 | ZFPL1 | O95159 | Zinc finger protein-like 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 127 | 16 | 16 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|