Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACAD9 | ACAD9 | Q9H845 | Complex I assembly factor ACAD9, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 69 | 28 | 5 | 5 | 12 |
| ACSL4_ENST00000469796 | ACSL4 | O60488 | Long-chain-fatty-acid--CoA ligase 4 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 97 | 77 | 12 | 12 | 1 |
| AGK | AGK | Q53H12 | Acylglycerol kinase, mitochondrial | chr7 | Not Cancer Driver | No | 1 | hippie | 71 | 77 | 6 | 6 | 0 |
| AGPAT2_ENST00000538402 | AGPAT2 | O15120 | 1-acyl-sn-glycerol-3-phosphate acyltransferase beta | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 23 | 2 | 2 | 3 |
| ALDOA_ENST00000643777 | ALDOA | P04075 | Fructose-bisphosphate aldolase A | chr16 | Not Cancer Driver | No | 1 | hippie | 47 | 65 | 9 | 9 | 3 |
| AQP1 | AQP1 | P29972 | Aquaporin-1 | chr7 | Not Cancer Driver | No | 1 | hippie | 39 | 4 | 1 | 1 | 0 |
| ARF5 | ARF5 | P84085 | ADP-ribosylation factor 5 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 11 | 2 | 2 | 0 |
| ARF6 | ARF6 | P62330 | ADP-ribosylation factor 6 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 5 | 0 | 0 | 0 |
| ATF2 | ATF2 | P15336 | Cyclic AMP-dependent transcription factor ATF-2 | chr2 | Not Cancer Driver | No | 1 | hippie | 65 | 451 | 58 | 58 | 0 |
| ATP11C | ATP11C | Q8NB49 | Phospholipid-transporting ATPase IG | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 198 | 32 | 5 | 5 | 1 |
| ATP1A3_ENST00000302102 | ATP1A3 | P13637 | Sodium/potassium-transporting ATPase subunit alpha-3 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 200 | 115 | 29 | 29 | 31 |
| ATP2B4_ENST00000341360 | ATP2B4 | P23634-2 | Isoform XA of Plasma membrane calcium-transporting ATPase 4 | chr1 | Not Cancer Driver | No | 1 | hippie | 145 | 219 | 21 | 21 | 0 |
| ATP6AP1 | ATP6AP1 | Q15904 | V-type proton ATPase subunit S1 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 0 | 0 | 0 | 4 |
| ATP6AP2 | ATP6AP2 | O75787 | Renin receptor | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 0 | 0 | 0 | 2 |
| ATP6V0A1_ENST00000343619 | ATP6V0A1 | Q93050 | V-type proton ATPase 116 kDa subunit a 1 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 98 | 85 | 14 | 14 | 0 |
| ATP6V0A2 | ATP6V0A2 | Q9Y487 | V-type proton ATPase 116 kDa subunit a 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 88 | 36 | 6 | 6 | 0 |
| ATP6V0D2 | ATP6V0D2 | Q8N8Y2 | V-type proton ATPase subunit d 2 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 0 | 0 | 0 | 0 |
| ATP6V1H_ENST00000396774 | ATP6V1H | Q9UI12 | V-type proton ATPase subunit H | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 76 | 35 | 2 | 2 | 0 |
| AUP1 | AUP1 | Q9Y679 | Lipid droplet-regulating VLDL assembly factor AUP1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 122 | 13 | 13 | 0 |
| B3GAT1_ENST00000312527 | B3GAT1 | Q9P2W7 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 85 | 93 | 32 | 32 | 0 |
| BET1 | BET1 | O15155 | BET1 homolog | chr7 | Not Cancer Driver | No | 1 | hippie | 14 | 7 | 2 | 2 | 0 |
| BMI1 | BMI1 | P35226 | Polycomb complex protein BMI-1 | chr10 | Not Cancer Driver | No | 1 | hippie | 50 | 150 | 30 | 30 | 0 |
| BRAT1 | BRAT1 | Q6PJG6 | BRCA1-associated ATM activator 1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 112 | 101 | 13 | 13 | 0 |
| BTAF1 | BTAF1 | O14981 | TATA-binding protein-associated factor 172 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 215 | 360 | 52 | 52 | 0 |
| BTF3 | BTF3 | P20290 | Transcription factor BTF3 | chr5 | Not Cancer Driver | No | 1 | hippie | 27 | 192 | 24 | 24 | 0 |
| C11orf52 | C11orf52 | Q96A22 | Uncharacterized protein C11orf52 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 108 | 12 | 12 | 0 |
| C19orf70_ENST00000309324 | MICOS13 | Q5XKP0 | MICOS complex subunit MIC13 | chr19 | Not Cancer Driver | No | 1 | hippie | 12 | 3 | 0 | 0 | 0 |
| CALCOCO2_ENST00000258947 | CALCOCO2 | Q13137 | Calcium-binding and coiled-coil domain-containing protein 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 42 | 212 | 19 | 19 | 0 |
| CALR | CALR | P27797 | Calreticulin | chr19 | Census | Yes | 1 | hippie | 45 | 245 | 31 | 31 | 0 |
| CAND1 | CAND1 | Q86VP6 | Cullin-associated NEDD8-dissociated protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 161 | 88 | 7 | 7 | 0 |
| CANX_ENST00000504734 | CANX | P27824 | Calnexin | chr5 | Not Cancer Driver | No | 1 | hippie | 65 | 334 | 38 | 38 | 0 |
| CCDC47_ENST00000403162 | CCDC47 | Q96A33 | PAT complex subunit CCDC47 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 265 | 23 | 23 | 0 |
| CCR2_ENST00000400888 | CCR2 | P41597 | C-C chemokine receptor type 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 81 | 23 | 1 | 1 | 0 |
| CD55_ENST00000367064 | CD55 | P08174 | Complement decay-accelerating factor | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 128 | 13 | 13 | 1 |
| CD81 | CD81 | P60033 | CD81 antigen | chr11 | Not Cancer Driver | No | 1 | hippie | 28 | 0 | 0 | 0 | 0 |
| CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 39 | 23 | 2 | 2 | 1 |
| CFTR | CFTR | P13569 | Cystic fibrosis transmembrane conductance regulator | chr7 | Not Cancer Driver | No | 1 | hippie | 287 | 145 | 18 | 18 | 151 |
| CHCHD6 | CHCHD6 | Q9BRQ6 | MICOS complex subunit MIC25 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 194 | 24 | 24 | 0 |
| CIAO1 | CIAO1 | O76071 | Probable cytosolic iron-sulfur protein assembly protein CIAO1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 20 | 2 | 2 | 0 |
| CIT_ENST00000261833 | CIT | O14578 | Citron Rho-interacting kinase | chr12 | Not Cancer Driver | No | 1 | hippie | 284 | 1017 | 160 | 160 | 3 |
| COIL | COIL | P38432 | Coilin | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 61 | 385 | 42 | 42 | 0 |
| COPS6 | COPS6 | Q7L5N1 | COP9 signalosome complex subunit 6 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 30 | 6 | 6 | 0 |
| COQ8B | COQ8B | Q96D53 | Atypical kinase COQ8B, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie | 53 | 117 | 15 | 15 | 8 |
| COX15 | COX15 | Q7KZN9 | Cytochrome c oxidase assembly protein COX15 homolog | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 0 | 0 | 0 | 2 |
| CPT1A_ENST00000539743 | CPT1A | P50416 | Carnitine O-palmitoyltransferase 1, liver isoform | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 144 | 62 | 10 | 10 | 15 |
| CREB3 | CREB3 | O43889 | Cyclic AMP-responsive element-binding protein 3 | chr9 | Not Cancer Driver | No | 1 | hippie | 33 | 168 | 11 | 11 | 0 |
| CSE1L | CSE1L | P55060 | Exportin-2 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 109 | 32 | 5 | 5 | 0 |
| CTBP1 | CTBP1 | Q13363 | C-terminal-binding protein 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 42 | 123 | 9 | 9 | 1 |
| CTPS2_ENST00000380241 | CTPS2 | Q9NRF8 | CTP synthase 2 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 65 | 9 | 9 | 0 |
| CYLD | CYLD | Q9NQC7 | Ubiquitin carboxyl-terminal hydrolase CYLD | chr16 | Census, Compendium | Yes | 1 | hippie | 116 | 213 | 31 | 31 | 3 |
| CYP2S1 | CYP2S1 | Q96SQ9 | Cytochrome P450 2S1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 75 | 46 | 10 | 10 | 0 |
| DDOST_ENST00000375048 | DDOST | P39656 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 13 | 3 | 3 | 1 |
| DDX39A | DDX39A | O00148 | ATP-dependent RNA helicase DDX39A | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 44 | 37 | 2 | 2 | 0 |
| DHCR24 | DHCR24 | Q15392 | Delta(24)-sterol reductase | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 55 | 0 | 0 | 0 | 6 |
| DNAJC5 | DNAJC5 | Q9H3Z4 | DnaJ homolog subfamily C member 5 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 46 | 6 | 6 | 1 |
| DPP4 | DPP4 | P27487 | Dipeptidyl peptidase 4 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 151 | 8 | 1 | 1 | 0 |
| EARS2_ENST00000449606 | EARS2 | Q5JPH6 | Probable glutamate--tRNA ligase, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 99 | 14 | 14 | 14 |
| ECPAS_ENST00000338205 | ECPAS | Q5VYK3 | Proteasome adapter and scaffold protein ECM29 | chr9 | Not Cancer Driver | No | 1 | hippie | 176 | 240 | 22 | 22 | 0 |
| EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 13 | 0 | 0 | 0 |
| EI24 | EI24 | O14681 | Etoposide-induced protein 2.4 homolog | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 12 | 1 | 1 | 0 |
| ELOVL5_ENST00000304434 | ELOVL5 | Q9NYP7 | Elongation of very long chain fatty acids protein 5 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 25 | 4 | 4 | 2 |
| EMC2 | EMC2 | Q15006 | ER membrane protein complex subunit 2 | chr8 | Not Cancer Driver | No | 1 | hippie | 48 | 29 | 3 | 3 | 0 |
| ERGIC1 | ERGIC1 | Q969X5 | Endoplasmic reticulum-Golgi intermediate compartment protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 26 | 2 | 2 | 0 |
| ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | hippie | 121 | 195 | 27 | 27 | 2 |
| ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
| EXD2 | EXD2 | Q9NVH0 | Exonuclease 3'-5' domain-containing protein 2 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 176 | 15 | 15 | 0 |
| FASTKD1 | FASTKD1 | Q53R41 | FAST kinase domain-containing protein 1, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 125 | 0 | 0 | 0 | 0 |
| FIS1 | FIS1 | Q9Y3D6 | Mitochondrial fission 1 protein | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 6 | 0 | 0 | 0 |
| GAPDH | GAPDH | P04406 | Glyceraldehyde-3-phosphate dehydrogenase | chr12 | Not Cancer Driver | No | 1 | hippie | 39 | 24 | 3 | 3 | 0 |
| GBF1 | GBF1 | Q92538 | Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 216 | 669 | 76 | 76 | 0 |
| GCN1 | GCN1 | Q92616 | eIF-2-alpha kinase activator GCN1 | chr12 | Not Cancer Driver | No | 1 | hippie | 327 | 117 | 16 | 16 | 0 |
| GEMIN4 | GEMIN4 | P57678 | Gem-associated protein 4 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 101 | 24 | 1 | 1 | 0 |
| GIPC1 | GIPC1 | O14908 | PDZ domain-containing protein GIPC1 | chr19 | Not Cancer Driver | No | 1 | hippie | 47 | 138 | 17 | 17 | 0 |
| GJD3 | GJD3 | Q8N144 | Gap junction delta-3 protein | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 5 | 79 | 0 | 0 | 0 |
| GPAT3_ENST00000395226 | GPAT3 | Q53EU6 | Glycerol-3-phosphate acyltransferase 3 | chr4 | Not Cancer Driver | No | 1 | hippie | 56 | 3 | 0 | 0 | 0 |
| GPR35_ENST00000403859 | GPR35 | Q9HC97 | G-protein coupled receptor 35 | chr2 | Not Cancer Driver | No | 1 | hippie | 57 | 0 | 0 | 0 | 0 |
| HECTD3 | HECTD3 | Q5T447 | E3 ubiquitin-protein ligase HECTD3 | chr1 | Not Cancer Driver | No | 1 | hippie | 88 | 55 | 5 | 5 | 0 |
| HSPB2 | HSPB2 | Q16082 | Heat shock protein beta-2 | chr11 | Not Cancer Driver | No | 1 | hippie | 25 | 103 | 11 | 11 | 0 |
| ICMT | ICMT | O60725 | Protein-S-isoprenylcysteine O-methyltransferase | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 0 | 0 | 0 | 0 |
| ILK_ENST00000299421 | ILK | Q13418 | Integrin-linked protein kinase | chr11 | Not Cancer Driver | No | 1 | hippie | 45 | 71 | 9 | 9 | 0 |
| IMMT | IMMT | Q16891 | MICOS complex subunit MIC60 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 97 | 400 | 50 | 50 | 0 |
| INTS1 | INTS1 | Q8N201 | Integrator complex subunit 1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 234 | 368 | 43 | 43 | 1 |
| IRAK1 | IRAK1 | P51617 | Interleukin-1 receptor-associated kinase 1 | chrX | Compendium | Yes | 1 | hippie | 71 | 337 | 39 | 39 | 0 |
| ITGA4 | ITGA4 | P13612 | Integrin alpha-4 | chr2 | Not Cancer Driver | No | 1 | hippie | 254 | 97 | 27 | 27 | 0 |
| JAK2 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | Census, Compendium | Yes | 1 | hippie | 136 | 59 | 5 | 5 | 5 |
| KDELR1 | KDELR1 | P24390 | ER lumen protein-retaining receptor 1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 0 | 0 | 0 | 0 |
| KDELR2 | KDELR2 | P33947 | ER lumen protein-retaining receptor 2 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 0 | 0 | 0 | 1 |
| KDELR3_ENST00000216014 | KDELR3 | O43731 | ER lumen protein-retaining receptor 3 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 0 | 0 | 0 | 0 |
| KRAS | KRAS | P01116 | GTPase KRas | chr12 | Census, Compendium | Yes | 1 | hippie, biogrid | 788 | 7 | 2 | 2 | 27 |
| LAMP1 | LAMP1 | P11279 | Lysosome-associated membrane glycoprotein 1 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 93 | 10 | 10 | 0 |
| LAMP2_ENST00000200639 | LAMP2 | P13473 | Lysosome-associated membrane glycoprotein 2 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 55 | 7 | 7 | 1 |
| LAMP3 | LAMP3 | Q9UQV4 | Lysosome-associated membrane glycoprotein 3 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 222 | 38 | 38 | 0 |
| LAMTOR1 | LAMTOR1 | Q6IAA8 | Ragulator complex protein LAMTOR1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 13 | 96 | 7 | 7 | 0 |
| LGALS9 | LGALS9 | O00182 | Galectin-9 | chr17 | Not Cancer Driver | No | 1 | hippie | 54 | 65 | 16 | 16 | 0 |
| LONP1 | LONP1 | P36776 | Lon protease homolog, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 99 | 175 | 15 | 15 | 10 |
| LRRC31 | LRRC31 | Q6UY01 | Leucine-rich repeat-containing protein 31 | chr3 | Not Cancer Driver | No | 1 | hippie | 109 | 80 | 10 | 10 | 0 |
| LTB4R2 | LTB4R2 | Q9NPC1 | Leukotriene B4 receptor 2 | chr14 | Not Cancer Driver | No | 1 | hippie | 29 | 55 | 11 | 11 | 0 |
| MAD2L2 | MAD2L2 | Q9UI95 | Mitotic spindle assembly checkpoint protein MAD2B | chr1 | Not Cancer Driver | No | 1 | hippie | 22 | 0 | 0 | 0 | 1 |
| MARCKS | MARCKS | P29966 | Myristoylated alanine-rich C-kinase substrate | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 328 | 14 | 14 | 0 |
| MGST3 | MGST3 | O14880 | Microsomal glutathione S-transferase 3 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 0 | 0 | 0 | 0 |
| MPDU1 | MPDU1 | O75352 | Mannose-P-dolichol utilization defect 1 protein | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 4 | 2 | 2 | 3 |
| MRPS12_ENST00000402029 | MRPS12 | O15235 | 28S ribosomal protein S12, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 59 | 11 | 11 | 0 |
| MSH2 | MSH2 | P43246 | DNA mismatch repair protein Msh2 | chr2 | Census | Yes | 1 | hippie, biogrid | 92 | 37 | 4 | 4 | 70 |
| MTIF2_ENST00000403721 | MTIF2 | P46199 | Translation initiation factor IF-2, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 101 | 112 | 9 | 9 | 0 |
| MTX2 | MTX2 | O75431 | Metaxin-2 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 0 | 0 | 0 | 0 |
| MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
| MYO6 | MYO6 | Q9UM54 | Unconventional myosin-VI | chr6 | Not Cancer Driver | No | 1 | hippie | 176 | 342 | 41 | 41 | 3 |
| NCLN | NCLN | Q969V3 | Nicalin | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 38 | 4 | 4 | 0 |
| NCSTN | NCSTN | Q92542 | Nicastrin | chr1 | Not Cancer Driver | No | 1 | hippie | 94 | 72 | 11 | 11 | 1 |
| NEIL3 | NEIL3 | Q8TAT5 | Endonuclease 8-like 3 | chr4 | Not Cancer Driver | No | 1 | hippie | 80 | 131 | 18 | 18 | 0 |
| NPC1 | NPC1 | O15118 | NPC intracellular cholesterol transporter 1 | chr18 | Not Cancer Driver | No | 1 | hippie | 155 | 24 | 0 | 0 | 150 |
| NR2C2_ENST00000393102 | NR2C2 | P49116 | Nuclear receptor subfamily 2 group C member 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 62 | 186 | 24 | 24 | 0 |
| NUP205 | NUP205 | Q92621 | Nuclear pore complex protein Nup205 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 251 | 101 | 16 | 16 | 1 |
| OXA1L_ENST00000604262 | OXA1L | Q15070 | Mitochondrial inner membrane protein OXA1L | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 81 | 9 | 9 | 0 |
| PARL | PARL | Q9H300 | Presenilins-associated rhomboid-like protein, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 28 | 5 | 5 | 0 |
| PDIA3 | PDIA3 | P30101 | Protein disulfide-isomerase A3 | chr15 | Not Cancer Driver | No | 1 | hippie | 57 | 98 | 11 | 11 | 0 |
| PDXDC1 | PDXDC1 | Q6P996 | Pyridoxal-dependent decarboxylase domain-containing protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 95 | 272 | 29 | 29 | 0 |
| PEX3 | PEX3 | P56589 | Peroxisomal biogenesis factor 3 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 24 | 0 | 0 | 2 |
| PGM3_ENST00000513973 | PGM3 | O95394 | Phosphoacetylglucosamine mutase | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 78 | 77 | 8 | 8 | 7 |
| PIK3R4 | PIK3R4 | Q99570 | Phosphoinositide 3-kinase regulatory subunit 4 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 193 | 315 | 45 | 45 | 0 |
| PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
| PLEKHA7 | PLEKHA7 | Q6IQ23 | Pleckstrin homology domain-containing family A member 7 | chr11 | Not Cancer Driver | No | 1 | hippie | 152 | 919 | 121 | 121 | 0 |
| PLSCR1 | PLSCR1 | O15162 | Phospholipid scramblase 1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 92 | 13 | 13 | 0 |
| PRKCB_ENST00000321728 | PRKCB | P05771 | Protein kinase C beta type | chr16 | Census, Compendium | Yes | 1 | hippie | 205 | 148 | 40 | 40 | 0 |
| PTK2B_ENST00000346049 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | Not Cancer Driver | No | 1 | hippie | 161 | 261 | 37 | 37 | 0 |
| RAB11A | RAB11A | P62491 | Ras-related protein Rab-11A | chr15 | Not Cancer Driver | No | 1 | hippie | 31 | 43 | 4 | 4 | 0 |
| RAB18_ENST00000356940 | RAB18 | Q9NP72 | Ras-related protein Rab-18 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 18 | 2 | 2 | 1 |
| RAB29 | RAB29 | O14966 | Ras-related protein Rab-7L1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 18 | 3 | 3 | 0 |
| RAB2A | RAB2A | P61019 | Ras-related protein Rab-2A | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 58 | 4 | 4 | 0 |
| RAB35 | RAB35 | Q15286 | Ras-related protein Rab-35 | chr12 | Not Cancer Driver | No | 2 | hippie, biogrid | 25 | 25 | 2 | 2 | 0 |
| RAB5C_ENST00000393860 | RAB5C | P51148 | Ras-related protein Rab-5C | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 50 | 4 | 4 | 0 |
| RAB9A | RAB9A | P51151 | Ras-related protein Rab-9A | chrX | Not Cancer Driver | No | 1 | hippie | 18 | 21 | 1 | 1 | 0 |
| RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | Census, Compendium | Yes | 1 | hippie | 66 | 2 | 1 | 1 | 6 |
| RAC2 | RAC2 | P15153 | Ras-related C3 botulinum toxin substrate 2 | chr22 | Not Cancer Driver | No | 1 | hippie | 31 | 0 | 0 | 0 | 2 |
| RAC3 | RAC3 | P60763 | Ras-related C3 botulinum toxin substrate 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 4 |
| RAD18 | RAD18 | Q9NS91 | E3 ubiquitin-protein ligase RAD18 | chr3 | Not Cancer Driver | No | 1 | hippie | 59 | 328 | 43 | 43 | 0 |
| RARS2 | RARS2 | Q5T160 | Probable arginine--tRNA ligase, mitochondrial | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 88 | 20 | 1 | 1 | 0 |
| RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | Census, Compendium | Yes | 1 | hippie | 99 | 46 | 13 | 13 | 2 |
| RHOB | RHOB | P62745 | Rho-related GTP-binding protein RhoB | chr2 | Not Cancer Driver | No | 2 | hippie, biogrid | 52 | 19 | 2 | 2 | 0 |
| RHOBTB1 | RHOBTB1 | O94844 | Rho-related BTB domain-containing protein 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 95 | 121 | 19 | 19 | 0 |
| RHOBTB2_ENST00000251822 | RHOBTB2 | Q9BYZ6 | Rho-related BTB domain-containing protein 2 | chr8 | Not Cancer Driver | No | 1 | hippie | 99 | 131 | 18 | 18 | 6 |
| RHOC_ENST00000369642 | RHOC | P08134 | Rho-related GTP-binding protein RhoC | chr1 | Not Cancer Driver | No | 1 | hippie | 30 | 53 | 7 | 7 | 0 |
| RHOD | RHOD | O00212 | Rho-related GTP-binding protein RhoD | chr11 | Not Cancer Driver | No | 1 | hippie | 20 | 10 | 0 | 0 | 0 |
| RHOF | RHOF | Q9HBH0 | Rho-related GTP-binding protein RhoF | chr12 | Not Cancer Driver | No | 1 | hippie | 18 | 10 | 0 | 0 | 0 |
| RHOG_ENST00000396978 | RHOG | P84095 | Rho-related GTP-binding protein RhoG | chr11 | Not Cancer Driver | No | 1 | hippie | 26 | 22 | 5 | 5 | 0 |
| RHOH_ENST00000617441 | RHOH | Q15669 | Rho-related GTP-binding protein RhoH | chr4 | Census | Yes | 1 | hippie | 41 | 12 | 3 | 3 | 0 |
| RHOJ | RHOJ | Q9H4E5 | Rho-related GTP-binding protein RhoJ | chr14 | Not Cancer Driver | No | 1 | hippie | 39 | 0 | 0 | 0 | 0 |
| RHOQ | RHOQ | P17081 | Rho-related GTP-binding protein RhoQ | chr2 | Not Cancer Driver | No | 1 | hippie | 25 | 0 | 0 | 0 | 0 |
| RHOU | RHOU | Q7L0Q8 | Rho-related GTP-binding protein RhoU | chr1 | Not Cancer Driver | No | 1 | hippie | 34 | 63 | 6 | 6 | 0 |
| RHOV | RHOV | Q96L33 | Rho-related GTP-binding protein RhoV | chr15 | Not Cancer Driver | No | 1 | hippie | 25 | 47 | 5 | 5 | 0 |
| RMC1 | RMC1 | Q96DM3 | Regulator of MON1-CCZ1 complex | chr18 | Not Cancer Driver | No | 1 | hippie | 70 | 12 | 0 | 0 | 0 |
| RND1 | RND1 | Q92730 | Rho-related GTP-binding protein Rho6 | chr12 | Not Cancer Driver | No | 1 | hippie | 45 | 9 | 1 | 1 | 0 |
| RND2 | RND2 | P52198 | Rho-related GTP-binding protein RhoN | chr17 | Not Cancer Driver | No | 1 | hippie | 19 | 54 | 4 | 4 | 0 |
| RND3_ENST00000263895 | RND3 | P61587 | Rho-related GTP-binding protein RhoE | chr2 | Not Cancer Driver | No | 1 | hippie | 36 | 70 | 10 | 10 | 0 |
| RNF4 | RNF4 | P78317 | E3 ubiquitin-protein ligase RNF4 | chr4 | Not Cancer Driver | No | 1 | hippie | 14 | 117 | 7 | 7 | 0 |
| RPGRIP1 | RPGRIP1 | Q96KN7 | X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 219 | 680 | 110 | 110 | 6 |
| SAMM50 | SAMM50 | Q9Y512 | Sorting and assembly machinery component 50 homolog | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 34 | 1 | 1 | 0 |
| SFXN2 | SFXN2 | Q96NB2 | Sideroflexin-2 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 44 | 0 | 0 | 0 | 0 |
| SIGMAR1 | SIGMAR1 | Q99720 | Sigma non-opioid intracellular receptor 1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 2 | 0 | 0 | 1 |
| SLC25A33 | SLC25A33 | Q9BSK2 | Solute carrier family 25 member 33 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 4 | 0 | 0 | 0 |
| SLC25A4 | SLC25A4 | P12235 | ADP/ATP translocase 1 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 0 | 0 | 0 | 9 |
| SLC25A51_ENST00000242275 | SLC25A51 | Q9H1U9 | Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 21 | 0 | 0 | 0 |
| SLC2A1 | SLC2A1 | P11166 | Solute carrier family 2, facilitated glucose transporter member 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 51 | 13 | 2 | 2 | 48 |
| SLC33A1_ENST00000643144 | SLC33A1 | O00400 | Acetyl-coenzyme A transporter 1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 54 | 8 | 8 | 2 |
| SLC4A1 | SLC4A1 | P02730 | Band 3 anion transport protein | chr17 | Not Cancer Driver | No | 1 | hippie | 153 | 130 | 23 | 23 | 39 |
| SLC7A1 | SLC7A1 | P30825 | High affinity cationic amino acid transporter 1 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 89 | 17 | 3 | 3 | 0 |
| SNX27 | SNX27 | Q96L92 | Sorting nexin-27 | chr1 | Not Cancer Driver | No | 1 | hippie | 65 | 120 | 9 | 9 | 0 |
| SPG7 | SPG7 | Q9UQ90 | Paraplegin | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 97 | 181 | 29 | 29 | 4 |
| STAU1 | STAU1 | O95793 | Double-stranded RNA-binding protein Staufen homolog 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 77 | 456 | 63 | 63 | 0 |
| STK17B_ENST00000409228 | STK17B | O94768 | Serine/threonine-protein kinase 17B | chr2 | Not Cancer Driver | No | 1 | hippie | 57 | 60 | 12 | 12 | 0 |
| STOM | STOM | P27105 | Stomatin | chr9 | Not Cancer Driver | No | 1 | hippie | 23 | 44 | 3 | 3 | 0 |
| STT3A_ENST00000529196 | STT3A | P46977 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 82 | 27 | 2 | 2 | 1 |
| STX17_ENST00000534052 | STX17 | P56962 | Syntaxin-17 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 81 | 4 | 4 | 0 |
| SUMO1_ENST00000392245 | SUMO1 | P63165 | Small ubiquitin-related modifier 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 10 | 76 | 7 | 7 | 0 |
| SUMO2 | SUMO2 | P61956 | Small ubiquitin-related modifier 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 9 | 69 | 6 | 6 | 0 |
| SURF4 | SURF4 | O15260 | Surfeit locus protein 4 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 0 | 0 | 0 | 0 |
| SYNJ2BP | SYNJ2BP | P57105 | Synaptojanin-2-binding protein | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 12 | 4 | 4 | 0 |
| SYVN1 | SYVN1 | Q86TM6 | E3 ubiquitin-protein ligase synoviolin | chr11 | Not Cancer Driver | No | 1 | hippie | 63 | 284 | 32 | 32 | 0 |
| TELO2 | TELO2 | Q9Y4R8 | Telomere length regulation protein TEL2 homolog | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 113 | 154 | 23 | 23 | 5 |
| TFB2M | TFB2M | Q9H5Q4 | Dimethyladenosine transferase 2, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 60 | 36 | 6 | 6 | 0 |
| TGOLN2_ENST00000377386 | TGOLN2 | O43493 | Trans-Golgi network integral membrane protein 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 51 | 399 | 46 | 46 | 0 |
| TIMMDC1 | TIMMDC1 | Q9NPL8 | Complex I assembly factor TIMMDC1, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 44 | 50 | 6 | 6 | 0 |
| TMCO1 | TMCO1 | Q9UM00 | Calcium load-activated calcium channel | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 49 | 5 | 5 | 0 |
| TMEM161A | TMEM161A | Q9NX61 | Transmembrane protein 161A | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 22 | 8 | 8 | 0 |
| TMEM192 | TMEM192 | Q8IY95 | Transmembrane protein 192 | chr4 | Not Cancer Driver | No | 1 | hippie | 31 | 5 | 1 | 1 | 0 |
| TMEM209 | TMEM209 | Q96SK2 | Transmembrane protein 209 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 193 | 27 | 27 | 0 |
| TMEM43 | TMEM43 | Q9BTV4 | Transmembrane protein 43 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 57 | 9 | 9 | 3 |
| TMEM70 | TMEM70 | Q9BUB7 | Transmembrane protein 70, mitochondrial | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 24 | 4 | 4 | 1 |
| TOLLIP | TOLLIP | Q9H0E2 | Toll-interacting protein | chr11 | Not Cancer Driver | No | 1 | hippie | 38 | 81 | 12 | 12 | 0 |
| TOMM22 | TOMM22 | Q9NS69 | Mitochondrial import receptor subunit TOM22 homolog | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 83 | 9 | 9 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 1 | hippie | 2891 | 282 | 1466 | 1466 | 83 |
| TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
| TSFM_ENST00000454289 | TSFM | P43897 | Elongation factor Ts, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 74 | 7 | 7 | 2 |
| TTI2_ENST00000360742 | TTI2 | Q6NXR4 | TELO2-interacting protein 2 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 55 | 80 | 8 | 8 | 1 |
| TTL | TTL | Q8NG68 | Tubulin--tyrosine ligase | chr2 | Not Cancer Driver | No | 1 | hippie | 37 | 24 | 0 | 0 | 0 |
| TUBB4A | TUBB4A | P04350 | Tubulin beta-4A chain | chr19 | Not Cancer Driver | No | 1 | hippie | 91 | 61 | 16 | 16 | 2 |
| TXNIP | TXNIP | Q9H3M7 | Thioredoxin-interacting protein | chr1 | Not Cancer Driver | No | 1 | hippie | 61 | 77 | 14 | 14 | 0 |
| TYK2 | TYK2 | P29597 | Non-receptor tyrosine-protein kinase TYK2 | chr19 | Not Cancer Driver | No | 1 | hippie | 148 | 213 | 29 | 29 | 0 |
| UBE2I | UBE2I | P63279 | SUMO-conjugating enzyme UBC9 | chr16 | Not Cancer Driver | No | 1 | hippie | 16 | 16 | 3 | 3 | 0 |
| VCAM1 | VCAM1 | P19320 | Vascular cell adhesion protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 188 | 110 | 28 | 28 | 0 |
| VHL | VHL | P40337 | von Hippel-Lindau disease tumor suppressor | chr3 | Census, Compendium | Yes | 1 | hippie | 142 | 117 | 36 | 36 | 133 |
| WWP1 | WWP1 | Q9H0M0 | NEDD4-like E3 ubiquitin-protein ligase WWP1 | chr8 | Not Cancer Driver | No | 1 | hippie | 139 | 431 | 75 | 75 | 0 |
| XPO1_ENST00000406957 | XPO1 | O14980 | Exportin-1 | chr2 | Census, Compendium | Yes | 1 | hippie, biogrid | 140 | 33 | 9 | 9 | 0 |
| XPOT | XPOT | O43592 | Exportin-T | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 114 | 0 | 0 | 0 | 0 |
| YIF1B | YIF1B | Q5BJH7 | Protein YIF1B | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 62 | 3 | 3 | 1 |
| YIPF5 | YIPF5 | Q969M3 | Protein YIPF5 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 57 | 6 | 6 | 1 |
| ZDHHC5 | ZDHHC5 | Q9C0B5 | Palmitoyltransferase ZDHHC5 | chr11 | Not Cancer Driver | No | 1 | hippie | 89 | 462 | 63 | 63 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|