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SLC16A1 ,SLC16A1 ,P53985
  • Uniprot Accession= P53985
  • Ensembl Transcript= ENST00000538576.5
  • Uniprot Name= SLC16A1
  • Name= Monocarboxylate transporter 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 1
  • Number of Interaction partner in biogrid: 42
  • Number of Interaction partner in hippie: 139
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 56 28 6 6 0
AFG3L2 AFG3L2 Q9Y4W6 AFG3-like protein 2 chr18 Not Cancer Driver No 1 hippie, biogrid 72 162 10 10 22
AGTR1_ENST00000349243 AGTR1 P30556 Type-1 angiotensin II receptor chr3 Not Cancer Driver No 1 hippie 95 0 0 0 1
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 107 537 67 67 0
AP1S1 AP1S1 P61966 AP-1 complex subunit sigma-1A chr7 Not Cancer Driver No 1 hippie, biogrid 21 0 0 0 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 hippie, biogrid 18 5 0 0 0
ARL6IP4_ENST00000543566 ARL6IP4 Q66PJ3-3 Isoform 3 of ADP-ribosylation factor-like protein 6-interacting protein 4 chr12 Not Cancer Driver No 1 hippie 16 386 15 15 0
ARRDC3 ARRDC3 Q96B67 Arrestin domain-containing protein 3 chr5 Not Cancer Driver No 1 hippie 52 95 12 12 0
ASXL1_ENST00000613218 ASXL1 Q8IXJ9 Polycomb group protein ASXL1 chr20 Census, Compendium Yes 1 hippie 205 1300 174 174 0
ATP2A2 ATP2A2 P16615 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 chr12 Not Cancer Driver No 1 hippie, biogrid 136 78 14 14 41
ATXN3 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 hippie 46 181 24 24 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BRD7_ENST00000394688 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 Compendium Yes 1 hippie 82 482 57 57 0
BRD9 BRD9 Q9H8M2 Bromodomain-containing protein 9 chr5 Not Cancer Driver No 1 hippie 77 385 44 44 0
BSG BSG P35613 Basigin chr19 Not Cancer Driver No 1 hippie 43 123 17 17 0
C19orf70_ENST00000309324 MICOS13 Q5XKP0 MICOS complex subunit MIC13 chr19 Not Cancer Driver No 1 hippie 12 3 0 0 0
CD44 CD44 P16070 CD44 antigen chr11 Not Cancer Driver No 1 hippie 75 542 60 60 0
CD81 CD81 P60033 CD81 antigen chr11 Not Cancer Driver No 1 hippie 28 0 0 0 0
CDC34 CDC34 P49427 Ubiquitin-conjugating enzyme E2 R1 chr19 Not Cancer Driver No 1 hippie 26 95 11 11 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 24 0 0 0 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 hippie 287 145 18 18 151
CHCHD10_ENST00000484558 CHCHD10 Q8WYQ3 Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial chr22 Not Cancer Driver No 1 hippie, biogrid 8 97 4 4 4
CIC CIC Q96RK0 Protein capicua homolog chr19 Census, Compendium Yes 1 hippie 276 1550 266 266 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CLN6 CLN6 Q9NWW5 Ceroid-lipofuscinosis neuronal protein 6 chr15 Not Cancer Driver No 1 hippie 28 13 0 0 24
COIL COIL P38432 Coilin chr17 Not Cancer Driver No 1 hippie, biogrid 61 385 42 42 0
COQ8A COQ8A Q8NI60 Atypical kinase COQ8A, mitochondrial chr1 Not Cancer Driver No 1 hippie 95 166 29 29 12
COQ9 COQ9 O75208 Ubiquinone biosynthesis protein COQ9, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 43 111 13 13 0
COX6B1_ENST00000592141 COX6B1 P14854 Cytochrome c oxidase subunit 6B1 chr19 Not Cancer Driver No 1 hippie 15 23 6 6 2
CRBN CRBN Q96SW2 Protein cereblon chr3 Not Cancer Driver No 1 hippie 52 76 10 10 1
CUL2_ENST00000374748 CUL2 Q13617 Cullin-2 chr10 Not Cancer Driver No 1 hippie 87 66 3 3 0
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 hippie 123 167 23 23 3
CYSTM1 CYSTM1 Q9H1C7 Cysteine-rich and transmembrane domain-containing protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 15 74 13 13 0
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 34 181 23 23 0
DEGS1_ENST00000391877 DEGS1 O15121 Sphingolipid delta(4)-desaturase DES1 chr1 Not Cancer Driver No 1 hippie, biogrid 50 2 0 0 4
DNAJC15 DNAJC15 Q9Y5T4 DnaJ homolog subfamily C member 15 chr13 Not Cancer Driver No 1 hippie, biogrid 19 25 4 4 0
DNAJC30 DNAJC30 Q96LL9 DnaJ homolog subfamily C member 30, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 25 83 7 7 3
DNAJC5 DNAJC5 Q9H3Z4 DnaJ homolog subfamily C member 5 chr20 Not Cancer Driver No 1 hippie, biogrid 23 46 6 6 1
DPF1_ENST00000456296 DPF1 Q92782 Zinc finger protein neuro-d4 chr19 Not Cancer Driver No 1 intact, hippie 32 85 7 7 0
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
FMC1 FMC1 Q96HJ9 Protein FMC1 homolog chr7 Not Cancer Driver No 1 hippie 9 30 1 1 0
GARNL3 GARNL3 Q5VVW2 GTPase-activating Rap/Ran-GAP domain-like protein 3 chr9 Not Cancer Driver No 1 hippie 115 285 34 34 0
HERC2 HERC2 O95714 E3 ubiquitin-protein ligase HERC2 chr15 Compendium Yes 1 hippie 718 971 150 150 1
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 hippie, biogrid 107 16 4 4 18
HSD17B12 HSD17B12 Q53GQ0 Very-long-chain 3-oxoacyl-CoA reductase chr11 Not Cancer Driver No 1 hippie, biogrid 32 9 0 0 0
ILK_ENST00000299421 ILK Q13418 Integrin-linked protein kinase chr11 Not Cancer Driver No 1 hippie 45 71 9 9 0
JMJD4 JMJD4 Q9H9V9 2-oxoglutarate and iron-dependent oxygenase JMJD4 chr1 Not Cancer Driver No 1 hippie, biogrid 67 19 5 5 0
KDF1 KDF1 Q8NAX2 Keratinocyte differentiation factor 1 chr1 Not Cancer Driver No 1 hippie 61 277 50 50 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 2 hippie, biogrid 788 7 2 2 27
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 Not Cancer Driver No 1 hippie 47 93 10 10 0
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 13 96 7 7 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 Not Cancer Driver No 1 hippie 54 65 16 16 0
LGR4 LGR4 Q9BXB1 Leucine-rich repeat-containing G-protein coupled receptor 4 chr11 Not Cancer Driver No 1 hippie 108 16 3 3 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 519 90 17 17 23
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie, biogrid 95 84 12 12 0
MAP1LC3B MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 Not Cancer Driver No 1 hippie 10 17 1 1 0
MAPK6 MAPK6 Q16659 Mitogen-activated protein kinase 6 chr15 Not Cancer Driver No 1 hippie 79 165 20 20 0
MARCKS MARCKS P29966 Myristoylated alanine-rich C-kinase substrate chr6 Not Cancer Driver No 1 hippie, biogrid 14 328 14 14 0
MME_ENST00000492661 MME P08473 Neprilysin chr3 Not Cancer Driver No 1 hippie 189 40 17 17 4
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NDUFA4 NDUFA4 O00483 Cytochrome c oxidase subunit NDUFA4 chr7 Not Cancer Driver No 1 hippie, biogrid 14 4 0 0 0
NDUFAF4 NDUFAF4 Q9P032 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 chr6 Not Cancer Driver No 1 hippie 14 46 4 4 2
NDUFS3 NDUFS3 O75489 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 34 26 3 3 2
NGDN NGDN Q8NEJ9 Neuroguidin chr14 Not Cancer Driver No 1 hippie 42 195 29 29 0
NIT1 NIT1 Q86X76 Deaminated glutathione amidase chr1 Not Cancer Driver No 1 hippie 41 18 3 3 0
NPC1 NPC1 O15118 NPC intracellular cholesterol transporter 1 chr18 Not Cancer Driver No 1 hippie 155 24 0 0 150
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
NRAS NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 284 10 0 0 14
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 hippie 31 33 2 2 0
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 70 43 6 6 20
PHKG2 PHKG2 P15735 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform chr16 Not Cancer Driver No 1 hippie 48 50 6 6 4
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLEKHG4 PLEKHG4 Q58EX7 Puratrophin-1 chr16 Not Cancer Driver No 1 hippie, biogrid 132 295 35 35 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 Not Cancer Driver No 1 hippie 2 23 1 1 0
POMK POMK Q9H5K3 Protein O-mannose kinase chr8 Not Cancer Driver No 1 hippie, biogrid 53 30 9 9 3
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 Not Cancer Driver No 1 hippie 72 124 17 17 0
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 Census, Compendium Yes 1 hippie 205 148 40 40 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 Not Cancer Driver No 1 hippie, biogrid 70 116 11 11 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 110 78 15 15 31
PTPMT1 PTPMT1 Q8WUK0 Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 chr11 Not Cancer Driver No 1 hippie, biogrid 16 0 0 0 0
PYHIN1 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 Not Cancer Driver No 1 hippie 174 291 99 99 0
RAB2A RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie, biogrid 22 58 4 4 0
RAB35 RAB35 Q15286 Ras-related protein Rab-35 chr12 Not Cancer Driver No 1 hippie, biogrid 25 25 2 2 0
RAB5C_ENST00000393860 RAB5C P51148 Ras-related protein Rab-5C chr17 Not Cancer Driver No 1 hippie, biogrid 24 50 4 4 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 66 2 1 1 6
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 Not Cancer Driver No 1 hippie 31 0 0 0 2
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 2 hippie, biogrid 52 19 2 2 0
RHOC_ENST00000369642 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 Not Cancer Driver No 1 hippie 30 53 7 7 0
RHOD RHOD O00212 Rho-related GTP-binding protein RhoD chr11 Not Cancer Driver No 1 hippie 20 10 0 0 0
RHOF RHOF Q9HBH0 Rho-related GTP-binding protein RhoF chr12 Not Cancer Driver No 1 hippie 18 10 0 0 0
RHOJ RHOJ Q9H4E5 Rho-related GTP-binding protein RhoJ chr14 Not Cancer Driver No 1 hippie 39 0 0 0 0
RHOQ RHOQ P17081 Rho-related GTP-binding protein RhoQ chr2 Not Cancer Driver No 1 hippie 25 0 0 0 0
RIPK4_ENST00000352483 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 hippie 119 232 34 34 3
RND2 RND2 P52198 Rho-related GTP-binding protein RhoN chr17 Not Cancer Driver No 1 hippie 19 54 4 4 0
RNF31 RNF31 Q96EP0 E3 ubiquitin-protein ligase RNF31 chr14 Not Cancer Driver No 1 hippie 142 319 45 45 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 Not Cancer Driver No 1 hippie 94 178 32 32 0
RYBP RYBP Q8N488 RING1 and YY1-binding protein chr3 Not Cancer Driver No 1 hippie 37 214 37 37 0
SEC61A1 SEC61A1 P61619 Protein transport protein Sec61 subunit alpha isoform 1 chr3 Not Cancer Driver No 1 hippie, biogrid 57 0 0 0 2
SEC63 SEC63 Q9UGP8 Translocation protein SEC63 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 98 266 37 37 0
SERINC3_ENST00000255175 SERINC3 Q13530 Serine incorporator 3 chr20 Not Cancer Driver No 1 hippie, biogrid 73 38 9 9 0
SLC16A11 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 33 72 5 5 0
SLC7A5 SLC7A5 Q01650 Large neutral amino acids transporter small subunit 1 chr16 Not Cancer Driver No 1 hippie, biogrid 62 35 1 1 0
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 Not Cancer Driver No 1 hippie 52 97 11 11 0
SOAT1 SOAT1 P35610 Sterol O-acyltransferase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 73 49 4 4 0
SPRTN SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 Not Cancer Driver No 1 hippie 73 252 38 38 1
SPTLC1 SPTLC1 O15269 Serine palmitoyltransferase 1 chr9 Not Cancer Driver No 1 hippie, biogrid 50 27 5 5 5
SRPRB SRPRB Q9Y5M8 Signal recognition particle receptor subunit beta chr3 Not Cancer Driver No 1 hippie, biogrid 30 23 3 3 0
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
STK32C STK32C Q86UX6 Serine/threonine-protein kinase 32C chr10 Not Cancer Driver No 1 hippie, biogrid 49 172 10 10 0
STX7 STX7 O15400 Syntaxin-7 chr6 Not Cancer Driver No 1 hippie, biogrid 29 164 14 14 0
SWAP70 SWAP70 Q9UH65 Switch-associated protein 70 chr11 Not Cancer Driver No 1 hippie 44 271 18 18 0
TECR TECR Q9NZ01 Very-long-chain enoyl-CoA reductase chr19 Not Cancer Driver No 1 hippie, biogrid 41 0 0 0 1
TENT5A TENT5A Q96IP4 Terminal nucleotidyltransferase 5A chr6 Not Cancer Driver No 1 hippie 43 0 0 0 0
TGOLN2_ENST00000377386 TGOLN2 O43493 Trans-Golgi network integral membrane protein 2 chr2 Not Cancer Driver No 1 hippie 51 399 46 46 0
THSD7A THSD7A Q9UPZ6 Thrombospondin type-1 domain-containing protein 7A chr7 Not Cancer Driver No 1 hippie 408 224 74 74 0
TMEM41B_ENST00000611268 TMEM41B Q5BJD5 Transmembrane protein 41B chr11 Not Cancer Driver No 1 hippie 19 47 3 3 0
TOMM22 TOMM22 Q9NS69 Mitochondrial import receptor subunit TOM22 homolog chr22 Not Cancer Driver No 1 hippie 18 83 9 9 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 hippie 67 62 7 7 0
TRIM14 TRIM14 Q14142 Tripartite motif-containing protein 14 chr9 Not Cancer Driver No 1 hippie 36 93 7 7 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TSC22D1 TSC22D1 Q15714 TSC22 domain family protein 1 chr13 Not Cancer Driver No 1 hippie 110 1023 98 98 0
TUBA1A TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 hippie 59 52 11 11 8
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 hippie 30 32 6 6 0
UBR5 UBR5 O95071 E3 ubiquitin-protein ligase UBR5 chr8 Census, Compendium Yes 1 hippie 340 1296 162 162 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
UNK UNK Q9C0B0 RING finger protein unkempt homolog chr17 Not Cancer Driver No 1 hippie 79 511 46 46 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 hippie 79 108 9 9 3
ZC3H18_ENST00000301011 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 1 hippie 139 929 134 134 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0