Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ACTBL2 | ACTBL2 | Q562R1 | Beta-actin-like protein 2 | chr5 | Not Cancer Driver | No | 1 | hippie | 73 | 29 | 5 | 5 | 0 |
ACTB_ENST00000646664 | ACTB | P60709 | Actin, cytoplasmic 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 112 | 43 | 5 | 5 | 5 |
AGO2 | AGO2 | Q9UKV8 | Protein argonaute-2 | chr8 | Not Cancer Driver | No | 1 | hippie | 126 | 141 | 15 | 15 | 11 |
AGRN | AGRN | O00468 | Agrin | chr1 | Not Cancer Driver | No | 1 | hippie | 188 | 490 | 40 | 40 | 5 |
AHNAK | AHNAK | Q09666 | Neuroblast differentiation-associated protein AHNAK | chr11 | Not Cancer Driver | No | 1 | hippie | 805 | 5777 | 794 | 794 | 0 |
AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | Census, Compendium | Yes | 1 | hippie | 108 | 158 | 24 | 24 | 4 |
AKT2 | AKT2 | P31751 | RAC-beta serine/threonine-protein kinase | chr19 | Census | Yes | 1 | hippie | 77 | 84 | 9 | 9 | 2 |
AR | AR | P10275 | Androgen receptor | chrX | Census, Compendium | Yes | 1 | hippie, biogrid | 196 | 443 | 88 | 88 | 169 |
ARMC8_ENST00000469044 | ARMC8 | Q8IUR7 | Armadillo repeat-containing protein 8 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 71 | 7 | 0 | 0 | 0 |
ATP1A1_ENST00000295598 | ATP1A1 | P05023 | Sodium/potassium-transporting ATPase subunit alpha-1 | chr1 | Census | Yes | 1 | hippie | 115 | 115 | 16 | 16 | 6 |
ATP2A2 | ATP2A2 | P16615 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 136 | 78 | 14 | 14 | 41 |
ATP5F1A_ENST00000282050 | ATP5F1A | P25705 | ATP synthase subunit alpha, mitochondrial | chr18 | Not Cancer Driver | No | 1 | hippie | 66 | 23 | 5 | 5 | 2 |
ATP5F1B | ATP5F1B | P06576 | ATP synthase subunit beta, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie | 60 | 85 | 8 | 8 | 0 |
ATP5PO | ATP5PO | P48047 | ATP synthase subunit O, mitochondrial | chr21 | Not Cancer Driver | No | 1 | hippie | 19 | 9 | 2 | 2 | 0 |
AXIN1 | AXIN1 | O15169 | Axin-1 | chr16 | Census, Compendium | Yes | 1 | hippie | 120 | 619 | 88 | 88 | 4 |
CAD | CAD | P27708 | CAD protein | chr2 | Not Cancer Driver | No | 1 | hippie | 287 | 368 | 52 | 52 | 1 |
CCT3 | CCT3 | P49368 | T-complex protein 1 subunit gamma | chr1 | Not Cancer Driver | No | 1 | hippie | 71 | 95 | 12 | 12 | 0 |
CDH1 | CDH1 | P12830 | Cadherin-1 | chr16 | Census, Compendium | Yes | 1 | hippie | 150 | 400 | 82 | 82 | 5 |
CELA2A | CELA2A | P08217 | Chymotrypsin-like elastase family member 2A | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 4 | 4 | 4 | 2 |
CIC | CIC | Q96RK0 | Protein capicua homolog | chr19 | Census, Compendium | Yes | 1 | hippie | 276 | 1550 | 266 | 266 | 0 |
COPB1_ENST00000439561 | COPB1 | P53618 | Coatomer subunit beta | chr11 | Not Cancer Driver | No | 1 | hippie | 110 | 95 | 10 | 10 | 1 |
DCAF7 | DCAF7 | P61962 | DDB1- and CUL4-associated factor 7 | chr17 | Not Cancer Driver | No | 1 | hippie | 48 | 0 | 0 | 0 | 0 |
DDX5 | DDX5 | P17844 | Probable ATP-dependent RNA helicase DDX5 | chr17 | Census | Yes | 1 | hippie | 74 | 225 | 23 | 23 | 0 |
DDX58 | DDX58 | O95786 | Antiviral innate immune response receptor RIG-I | chr9 | Not Cancer Driver | No | 1 | hippie | 118 | 61 | 10 | 10 | 2 |
DIAPH1 | DIAPH1 | O60610 | Protein diaphanous homolog 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 118 | 692 | 57 | 57 | 1 |
DYNC1H1 | DYNC1H1 | Q14204 | Cytoplasmic dynein 1 heavy chain 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 505 | 495 | 62 | 62 | 21 |
DYRK1B_ENST00000323039 | DYRK1B | Q9Y463 | Dual specificity tyrosine-phosphorylation-regulated kinase 1B | chr19 | Not Cancer Driver | No | 1 | hippie | 77 | 319 | 38 | 38 | 2 |
EPPK1 | EPPK1 | P58107 | Epiplakin | chr8 | Not Cancer Driver | No | 1 | hippie | 417 | 1336 | 67 | 67 | 0 |
ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | hippie | 121 | 195 | 27 | 27 | 2 |
EYA3 | EYA3 | Q99504 | Eyes absent homolog 3 | chr1 | Not Cancer Driver | No | 1 | hippie | 58 | 310 | 40 | 40 | 0 |
GATA1 | GATA1 | P15976 | Erythroid transcription factor | chrX | Census, Compendium | Yes | 1 | hippie | 68 | 242 | 41 | 41 | 5 |
GID8 | GID8 | Q9NWU2 | Glucose-induced degradation protein 8 homolog | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 60 | 6 | 6 | 0 |
GLI2_ENST00000361492 | GLI2 | P10070 | Zinc finger protein GLI2 | chr2 | Not Cancer Driver | No | 1 | hippie | 287 | 1403 | 244 | 244 | 2 |
GLI3 | GLI3 | P10071 | Transcriptional activator GLI3 | chr7 | Not Cancer Driver | No | 1 | hippie | 385 | 1352 | 327 | 327 | 7 |
GRPEL1 | GRPEL1 | Q9HAV7 | GrpE protein homolog 1, mitochondrial | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 88 | 7 | 7 | 0 |
HADHA | HADHA | P40939 | Trifunctional enzyme subunit alpha, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 72 | 19 | 2 | 2 | 5 |
HADHB | HADHB | P55084 | Trifunctional enzyme subunit beta, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 71 | 41 | 9 | 9 | 14 |
HDAC1 | HDAC1 | Q13547 | Histone deacetylase 1 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 47 | 135 | 10 | 10 | 0 |
HDAC3 | HDAC3 | O15379 | Histone deacetylase 3 | chr5 | Not Cancer Driver | No | 2 | intact, hippie | 65 | 61 | 8 | 8 | 0 |
HIPK2 | HIPK2 | Q9H2X6 | Homeodomain-interacting protein kinase 2 | chr7 | Not Cancer Driver | No | 1 | hippie | 154 | 686 | 96 | 96 | 0 |
HNRNPL | HNRNPL | P14866 | Heterogeneous nuclear ribonucleoprotein L | chr19 | Not Cancer Driver | No | 1 | hippie | 89 | 283 | 29 | 29 | 0 |
HNRNPM | HNRNPM | P52272 | Heterogeneous nuclear ribonucleoprotein M | chr19 | Not Cancer Driver | No | 1 | hippie | 108 | 463 | 67 | 67 | 0 |
HS3ST4 | HS3ST4 | Q9Y661 | Heparan sulfate glucosamine 3-O-sulfotransferase 4 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 115 | 216 | 18 | 18 | 0 |
HSP90AB1 | HSP90AB1 | P08238 | Heat shock protein HSP 90-beta | chr6 | Census, Compendium | Yes | 1 | hippie | 100 | 254 | 43 | 43 | 0 |
HSPA1L | HSPA1L | P34931 | Heat shock 70 kDa protein 1-like | chr6 | Not Cancer Driver | No | 1 | hippie | 119 | 141 | 28 | 28 | 0 |
HSPA5 | HSPA5 | P11021 | Endoplasmic reticulum chaperone BiP | chr9 | Not Cancer Driver | No | 1 | hippie | 73 | 282 | 35 | 35 | 0 |
HSPA6 | HSPA6 | P17066 | Heat shock 70 kDa protein 6 | chr1 | Not Cancer Driver | No | 1 | hippie | 112 | 235 | 27 | 27 | 0 |
HSPA8_ENST00000532636 | HSPA8 | P11142 | Heat shock cognate 71 kDa protein | chr11 | Not Cancer Driver | No | 1 | hippie | 149 | 251 | 52 | 52 | 0 |
HSPA9 | HSPA9 | P38646 | Stress-70 protein, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie | 67 | 283 | 26 | 26 | 2 |
HSPD1 | HSPD1 | P10809 | 60 kDa heat shock protein, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 61 | 82 | 6 | 6 | 2 |
HSPG2 | HSPG2 | P98160 | Basement membrane-specific heparan sulfate proteoglycan core protein | chr1 | Compendium | Yes | 1 | hippie | 506 | 1709 | 194 | 194 | 1 |
ITGB4 | ITGB4 | P16144 | Integrin beta-4 | chr17 | Not Cancer Driver | No | 1 | hippie | 248 | 753 | 86 | 86 | 14 |
JUN | JUN | P05412 | Transcription factor Jun | chr1 | Census | Yes | 1 | hippie | 35 | 281 | 25 | 25 | 0 |
KLF15 | KLF15 | Q9UIH9 | Krueppel-like factor 15 | chr3 | Not Cancer Driver | No | 1 | hippie | 66 | 273 | 48 | 48 | 0 |
KRT37 | KRT37 | O76014 | Keratin, type I cuticular Ha7 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 105 | 80 | 18 | 18 | 0 |
LATS2 | LATS2 | Q9NRM7 | Serine/threonine-protein kinase LATS2 | chr13 | Census, Compendium | Yes | 1 | hippie | 178 | 687 | 116 | 116 | 0 |
LDHA_ENST00000422447 | LDHA | P00338 | L-lactate dehydrogenase A chain | chr11 | Not Cancer Driver | No | 1 | hippie | 40 | 9 | 0 | 0 | 0 |
LTBR | LTBR | P36941 | Tumor necrosis factor receptor superfamily member 3 | chr12 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 44 | 200 | 21 | 21 | 0 |
MAEA | MAEA | Q7L5Y9 | E3 ubiquitin-protein transferase MAEA | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 64 | 5 | 5 | 0 |
MECP2_ENST00000303391 | MECP2 | P51608 | Methyl-CpG-binding protein 2 | chrX | Not Cancer Driver | No | 1 | hippie | 75 | 483 | 74 | 74 | 46 |
MERTK_ENST00000421804 | MERTK | Q12866 | Tyrosine-protein kinase Mer | chr2 | Not Cancer Driver | No | 1 | hippie | 175 | 159 | 31 | 31 | 3 |
MKLN1 | MKLN1 | Q9UL63 | Muskelin | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 85 | 91 | 13 | 13 | 0 |
MOB1A | MOB1A | Q9H8S9 | MOB kinase activator 1A | chr2 | Not Cancer Driver | No | 1 | hippie | 16 | 10 | 2 | 2 | 0 |
MOB1B_ENST00000309395 | MOB1B | Q7L9L4 | MOB kinase activator 1B | chr4 | Not Cancer Driver | No | 1 | hippie | 17 | 7 | 0 | 0 | 0 |
MVP | MVP | Q14764 | Major vault protein | chr16 | Not Cancer Driver | No | 1 | hippie | 141 | 285 | 31 | 31 | 0 |
MYB_ENST00000367814 | MYB | P10242 | Transcriptional activator Myb | chr6 | Census | Yes | 1 | hippie | 82 | 528 | 69 | 69 | 0 |
NCL | NCL | P19338 | Nucleolin | chr2 | Not Cancer Driver | No | 1 | hippie | 85 | 569 | 68 | 68 | 0 |
NCOR1 | NCOR1 | O75376 | Nuclear receptor corepressor 1 | chr17 | Census, Compendium | Yes | 1 | intact, hippie | 352 | 2347 | 340 | 340 | 0 |
NCOR2 | NCOR2 | Q9Y618 | Nuclear receptor corepressor 2 | chr12 | Census, Compendium | Yes | 1 | intact, hippie | 373 | 2355 | 356 | 356 | 0 |
NFIX_ENST00000592199 | NFIX | Q14938 | Nuclear factor 1 X-type | chr19 | Not Cancer Driver | No | 1 | hippie | 60 | 305 | 40 | 40 | 6 |
NLK | NLK | Q9UBE8 | Serine/threonine-protein kinase NLK | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 54 | 152 | 20 | 20 | 0 |
PABPC1 | PABPC1 | P11940 | Polyadenylate-binding protein 1 | chr8 | Census, Compendium | Yes | 1 | hippie | 100 | 317 | 55 | 55 | 0 |
PABPC4_ENST00000372857 | PABPC4 | Q13310 | Polyadenylate-binding protein 4 | chr1 | Not Cancer Driver | No | 1 | hippie | 89 | 253 | 49 | 49 | 0 |
PAX3_ENST00000350526 | PAX3 | P23760 | Paired box protein Pax-3 | chr2 | Census | Yes | 1 | intact | 113 | 391 | 95 | 95 | 28 |
PCNA | PCNA | P12004 | Proliferating cell nuclear antigen | chr20 | Not Cancer Driver | No | 1 | hippie | 30 | 22 | 3 | 3 | 1 |
PFKP | PFKP | Q01813 | ATP-dependent 6-phosphofructokinase, platelet type | chr10 | Not Cancer Driver | No | 1 | hippie | 133 | 43 | 10 | 10 | 0 |
PLEC | PLEC | Q15149 | Plectin | chr8 | Not Cancer Driver | No | 1 | hippie | 677 | 2130 | 272 | 272 | 2 |
PML | PML | P29590 | Protein PML | chr15 | Census, Compendium | Yes | 1 | hippie | 112 | 312 | 34 | 34 | 0 |
PPM1B | PPM1B | O75688 | Protein phosphatase 1B | chr2 | Not Cancer Driver | No | 1 | hippie | 65 | 243 | 31 | 31 | 0 |
PRDM16 | PRDM16 | Q9HAZ2 | Histone-lysine N-methyltransferase PRDM16 | chr1 | Census | Yes | 1 | hippie | 254 | 830 | 152 | 152 | 1 |
PRDX1_ENST00000319248 | PRDX1 | Q06830 | Peroxiredoxin-1 | chr1 | Not Cancer Driver | No | 1 | hippie | 22 | 40 | 5 | 5 | 0 |
PRKDC | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | Not Cancer Driver | No | 1 | hippie | 538 | 421 | 61 | 61 | 2 |
PRMT5 | PRMT5 | O14744 | Protein arginine N-methyltransferase 5 | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 83 | 72 | 6 | 6 | 0 |
PYGB | PYGB | P11216 | Glycogen phosphorylase, brain form | chr20 | Not Cancer Driver | No | 1 | hippie | 118 | 29 | 5 | 5 | 0 |
RACK1 | RACK1 | P63244 | Receptor of activated protein C kinase 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 34 | 13 | 0 | 0 | 0 |
RALBP1 | RALBP1 | Q15311 | RalA-binding protein 1 | chr18 | Not Cancer Driver | No | 2 | hippie, biogrid | 65 | 381 | 46 | 46 | 0 |
RANBP9 | RANBP9 | Q96S59 | Ran-binding protein 9 | chr6 | Not Cancer Driver | No | 1 | hippie | 73 | 413 | 30 | 30 | 0 |
RARA | RARA | P10276 | Retinoic acid receptor alpha | chr17 | Census, Compendium | Yes | 1 | hippie | 70 | 167 | 14 | 14 | 0 |
RAVER1_ENST00000615032 | RAVER1 | Q8IY67 | Ribonucleoprotein PTB-binding 1 | chr19 | Not Cancer Driver | No | 1 | intact | 61 | 330 | 22 | 22 | 0 |
RB1 | RB1 | P06400 | Retinoblastoma-associated protein | chr13 | Census, Compendium | Yes | 1 | hippie | 140 | 282 | 32 | 32 | 22 |
RB1CC1 | RB1CC1 | Q8TDY2 | RB1-inducible coiled-coil protein 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 202 | 578 | 75 | 75 | 0 |
RMND5A | RMND5A | Q9H871 | E3 ubiquitin-protein transferase RMND5A | chr2 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 46 | 0 | 0 | 0 | 0 |
RNF111_ENST00000557998 | RNF111 | Q6ZNA4 | E3 ubiquitin-protein ligase Arkadia | chr15 | Not Cancer Driver | No | 1 | hippie | 111 | 855 | 96 | 96 | 0 |
RNF165 | RNF165 | Q6ZSG1 | E3 ubiquitin-protein ligase RNF165 | chr18 | Not Cancer Driver | No | 1 | intact, hippie | 62 | 225 | 40 | 40 | 0 |
RPL12 | RPL12 | P30050 | 60S ribosomal protein L12 | chr9 | Not Cancer Driver | No | 1 | hippie | 13 | 75 | 6 | 6 | 0 |
RPL14_ENST00000396203 | RPL14 | P50914 | 60S ribosomal protein L14 | chr3 | Not Cancer Driver | No | 1 | hippie | 21 | 129 | 13 | 13 | 0 |
RPL18 | RPL18 | Q07020 | 60S ribosomal protein L18 | chr19 | Not Cancer Driver | No | 1 | hippie | 16 | 98 | 6 | 6 | 0 |
RPL30 | RPL30 | P62888 | 60S ribosomal protein L30 | chr8 | Not Cancer Driver | No | 1 | hippie | 4 | 11 | 0 | 0 | 0 |
RPL4 | RPL4 | P36578 | 60S ribosomal protein L4 | chr15 | Not Cancer Driver | No | 1 | hippie | 49 | 222 | 31 | 31 | 0 |
RPLP0_ENST00000228306 | RPLP0 | P05388 | 60S acidic ribosomal protein P0 | chr12 | Not Cancer Driver | No | 1 | hippie | 44 | 36 | 4 | 4 | 0 |
RPS16 | RPS16 | P62249 | 40S ribosomal protein S16 | chr19 | Not Cancer Driver | No | 1 | hippie | 16 | 14 | 1 | 1 | 0 |
RPS3_ENST00000527446 | RPS3 | P23396 | 40S ribosomal protein S3 | chr11 | Not Cancer Driver | No | 1 | hippie | 22 | 48 | 4 | 4 | 0 |
RPS4X | RPS4X | P62701 | 40S ribosomal protein S4, X isoform | chrX | Not Cancer Driver | No | 1 | hippie | 32 | 35 | 6 | 6 | 0 |
S100A7A_ENST00000329256 | S100A7A | Q86SG5 | Protein S100-A7A | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 20 | 12 | 12 | 0 |
SAV1 | SAV1 | Q9H4B6 | Protein salvador homolog 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 42 | 243 | 17 | 17 | 0 |
SCHIP1 | SCHIP1 | P0DPB3-4 | Isoform SCHIP1-4 of Schwannomin-interacting protein 1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 202 | 45 | 45 | 0 |
SERPINA3_ENST00000393080 | SERPINA3 | P01011 | Alpha-1-antichymotrypsin | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 117 | 18 | 10 | 10 | 0 |
SERPINB3 | SERPINB3 | P29508 | Serpin B3 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 142 | 47 | 28 | 28 | 0 |
SERPINB4 | SERPINB4 | P48594 | Serpin B4 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 120 | 48 | 18 | 18 | 0 |
SHARPIN | SHARPIN | Q9H0F6 | Sharpin | chr8 | Not Cancer Driver | No | 1 | hippie | 34 | 237 | 16 | 16 | 0 |
SIAH2 | SIAH2 | O43255 | E3 ubiquitin-protein ligase SIAH2 | chr3 | Not Cancer Driver | No | 1 | hippie | 48 | 68 | 3 | 3 | 0 |
SIN3A_ENST00000360439 | SIN3A | Q96ST3 | Paired amphipathic helix protein Sin3a | chr15 | Compendium | Yes | 3 | intact, hippie | 172 | 617 | 73 | 73 | 0 |
SIRT1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | Not Cancer Driver | No | 1 | hippie | 70 | 435 | 31 | 31 | 0 |
SIX1_ENST00000645694 | SIX1 | Q15475 | Homeobox protein SIX1 | chr14 | Census, Compendium | Yes | 1 | hippie | 49 | 144 | 25 | 25 | 8 |
SKI | SKI | P12755 | Ski oncogene | chr1 | Census | Yes | 1 | hippie | 44 | 432 | 26 | 26 | 14 |
SKIL_ENST00000259119 | SKIL | P12757 | Ski-like protein | chr3 | Not Cancer Driver | No | 2 | hippie, biogrid | 77 | 356 | 32 | 32 | 0 |
SLC25A13_ENST00000265631 | SLC25A13 | Q9UJS0 | Calcium-binding mitochondrial carrier protein Aralar2 | chr7 | Not Cancer Driver | No | 1 | hippie | 111 | 23 | 2 | 2 | 1 |
SLC25A4 | SLC25A4 | P12235 | ADP/ATP translocase 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 9 |
SLC25A5 | SLC25A5 | P05141 | ADP/ATP translocase 2 | chrX | Not Cancer Driver | No | 1 | hippie | 41 | 0 | 0 | 0 | 0 |
SLC25A6 | SLC25A6 | P12236 | ADP/ATP translocase 3 | chrX | Not Cancer Driver | No | 1 | hippie | 41 | 0 | 0 | 0 | 0 |
SMAD1 | SMAD1 | Q15797 | Mothers against decapentaplegic homolog 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 54 | 161 | 22 | 22 | 0 |
SMAD2_ENST00000402690 | SMAD2 | Q15796 | Mothers against decapentaplegic homolog 2 | chr18 | Census, Compendium | Yes | 6 | intact, hippie, biogrid | 79 | 137 | 12 | 12 | 0 |
SMAD3 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | Census, Compendium | Yes | 4 | intact, hippie | 97 | 111 | 19 | 19 | 5 |
SMAD4_ENST00000398417 | SMAD4 | Q13485 | Mothers against decapentaplegic homolog 4 | chr18 | Census, Compendium | Yes | 8 | intact, hippie, biogrid | 198 | 195 | 17 | 17 | 8 |
SMAD5_ENST00000509297 | SMAD5 | Q99717 | Mothers against decapentaplegic homolog 5 | chr5 | Not Cancer Driver | No | 1 | hippie | 44 | 172 | 11 | 11 | 0 |
SMAD7 | SMAD7 | O15105 | Mothers against decapentaplegic homolog 7 | chr18 | Not Cancer Driver | No | 2 | intact | 40 | 139 | 0 | 0 | 0 |
SMURF1 | SMURF1 | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 | chr7 | Not Cancer Driver | No | 1 | hippie | 89 | 256 | 31 | 31 | 0 |
SMURF2 | SMURF2 | Q9HAU4 | E3 ubiquitin-protein ligase SMURF2 | chr17 | Not Cancer Driver | No | 1 | hippie | 87 | 242 | 28 | 28 | 0 |
SNW1_ENST00000261531 | SNW1 | Q13573 | SNW domain-containing protein 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 62 | 488 | 56 | 56 | 0 |
SPI1_ENST00000378538 | SPI1 | P17947 | Transcription factor PU.1 | chr11 | Not Cancer Driver | No | 1 | hippie | 46 | 187 | 34 | 34 | 0 |
SQOR_ENST00000568606 | SQOR | Q9Y6N5 | Sulfide:quinone oxidoreductase, mitochondrial | chr15 | Not Cancer Driver | No | 1 | hippie | 54 | 41 | 8 | 8 | 1 |
SQSTM1 | SQSTM1 | Q13501 | Sequestosome-1 | chr5 | Not Cancer Driver | No | 1 | hippie | 54 | 267 | 32 | 32 | 30 |
STK38 | STK38 | Q15208 | Serine/threonine-protein kinase 38 | chr6 | Not Cancer Driver | No | 1 | hippie | 57 | 77 | 6 | 6 | 0 |
STK38L | STK38L | Q9Y2H1 | Serine/threonine-protein kinase 38-like | chr12 | Not Cancer Driver | No | 1 | hippie | 51 | 86 | 12 | 12 | 0 |
TBL1XR1 | TBL1XR1 | Q9BZK7 | F-box-like/WD repeat-containing protein TBL1XR1 | chr3 | Census, Compendium | Yes | 1 | hippie | 82 | 136 | 19 | 19 | 4 |
TBR1 | TBR1 | Q16650 | T-box brain protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 88 | 413 | 56 | 56 | 5 |
TCP1 | TCP1 | P17987 | T-complex protein 1 subunit alpha | chr6 | Not Cancer Driver | No | 1 | hippie | 54 | 55 | 10 | 10 | 0 |
TEAD1_ENST00000638666 | TEAD1 | P28347 | Transcriptional enhancer factor TEF-1 | chr11 | Not Cancer Driver | No | 1 | hippie | 52 | 157 | 24 | 24 | 1 |
TEAD4 | TEAD4 | Q15561 | Transcriptional enhancer factor TEF-3 | chr12 | Not Cancer Driver | No | 1 | hippie | 72 | 171 | 34 | 34 | 0 |
TGFBR1_ENST00000374994 | TGFBR1 | P36897 | TGF-beta receptor type-1 | chr9 | Not Cancer Driver | No | 1 | hippie | 86 | 23 | 3 | 3 | 15 |
TLX2 | TLX2 | O43763 | T-cell leukemia homeobox protein 2 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 24 | 220 | 15 | 15 | 0 |
TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 1 | hippie | 2891 | 282 | 1466 | 1466 | 83 |
TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
TRIM28 | TRIM28 | Q13263 | Transcription intermediary factor 1-beta | chr19 | Not Cancer Driver | No | 1 | hippie | 87 | 430 | 41 | 41 | 0 |
TRIM33 | TRIM33 | Q9UPN9 | E3 ubiquitin-protein ligase TRIM33 | chr1 | Census, Compendium | Yes | 1 | hippie | 110 | 617 | 51 | 51 | 0 |
TRIM37 | TRIM37 | O94972 | E3 ubiquitin-protein ligase TRIM37 | chr17 | Not Cancer Driver | No | 1 | hippie | 119 | 492 | 60 | 60 | 3 |
TUBA1A | TUBA1A | Q71U36 | Tubulin alpha-1A chain | chr12 | Not Cancer Driver | No | 1 | hippie | 59 | 52 | 11 | 11 | 8 |
TUBA1B | TUBA1B | P68363 | Tubulin alpha-1B chain | chr12 | Not Cancer Driver | No | 1 | hippie | 41 | 52 | 9 | 9 | 0 |
TUBA4A | TUBA4A | P68366 | Tubulin alpha-4A chain | chr2 | Not Cancer Driver | No | 1 | hippie | 73 | 39 | 4 | 4 | 5 |
TUBB | TUBB | P07437 | Tubulin beta chain | chr6 | Not Cancer Driver | No | 1 | hippie | 40 | 63 | 11 | 11 | 5 |
TUBB2A | TUBB2A | Q13885 | Tubulin beta-2A chain | chr6 | Not Cancer Driver | No | 1 | hippie | 44 | 70 | 13 | 13 | 2 |
TUBB6 | TUBB6 | Q9BUF5 | Tubulin beta-6 chain | chr18 | Not Cancer Driver | No | 1 | hippie | 69 | 51 | 5 | 5 | 1 |
TUFM | TUFM | P49411 | Elongation factor Tu, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie | 51 | 50 | 3 | 3 | 1 |
UBE2I | UBE2I | P63279 | SUMO-conjugating enzyme UBC9 | chr16 | Not Cancer Driver | No | 1 | hippie | 16 | 16 | 3 | 3 | 0 |
UBR3 | UBR3 | Q6ZT12 | E3 ubiquitin-protein ligase UBR3 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 154 | 339 | 28 | 28 | 0 |
UQCRC2 | UQCRC2 | P22695 | Cytochrome b-c1 complex subunit 2, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie | 53 | 48 | 13 | 13 | 1 |
VIRMA | VIRMA | Q69YN4 | Protein virilizer homolog | chr8 | Not Cancer Driver | No | 1 | hippie | 211 | 631 | 93 | 93 | 0 |
WDR26 | WDR26 | Q9H7D7 | WD repeat-containing protein 26 | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 71 | 187 | 9 | 9 | 0 |
WDR77 | WDR77 | Q9BQA1 | Methylosome protein 50 | chr1 | Not Cancer Driver | No | 1 | hippie | 30 | 41 | 2 | 2 | 0 |
ZMYND19 | ZMYND19 | Q96E35 | Zinc finger MYND domain-containing protein 19 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 20 | 4 | 4 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
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