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SIPA1L2 ,SIPA1L2 ,Q9P2F8
  • Uniprot Accession= Q9P2F8
  • Ensembl Transcript= ENST00000366630.5
  • Uniprot Name= SIPA1L2
  • Name= Signal-induced proliferation-associated 1-like protein 2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 2
  • Number of Interaction partner in biogrid: 71
  • Number of Interaction partner in hippie: 104
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie, biogrid 112 43 5 5 5
ACTR3 ACTR3 P61158 Actin-related protein 3 chr2 Not Cancer Driver No 1 hippie, biogrid 32 16 2 2 0
AFDN_ENST00000447894 AFDN P55196 Afadin chr6 Census Yes 1 hippie 248 1247 180 180 0
AMOT AMOT Q4VCS5 Angiomotin chrX Not Cancer Driver No 1 hippie, biogrid 161 909 128 128 0
ANAPC2 ANAPC2 Q9UJX6 Anaphase-promoting complex subunit 2 chr9 Not Cancer Driver No 1 hippie, biogrid 104 146 26 26 0
ANKFY1_ENST00000341657 ANKFY1 Q9P2R3 Rabankyrin-5 chr17 Not Cancer Driver No 1 hippie, biogrid 109 185 29 29 0
AP3M1 AP3M1 Q9Y2T2 AP-3 complex subunit mu-1 chr10 Not Cancer Driver No 1 hippie 45 19 1 1 0
APOBEC3D APOBEC3D Q96AK3 DNA dC->dU-editing enzyme APOBEC-3D chr22 Not Cancer Driver No 2 hippie, biogrid 43 3 0 0 0
BICD1 BICD1 Q96G01 Protein bicaudal D homolog 1 chr12 Not Cancer Driver No 1 hippie 124 656 86 86 0
BORCS6 BORCS6 Q96GS4 BLOC-1-related complex subunit 6 chr17 Not Cancer Driver No 1 hippie 17 269 11 11 0
C6orf141 C6orf141 Q5SZD1 Uncharacterized protein C6orf141 chr6 Not Cancer Driver No 2 hippie, biogrid 12 226 9 9 0
CCDC96 CCDC96 Q2M329 Coiled-coil domain-containing protein 96 chr4 Not Cancer Driver No 1 hippie, biogrid 74 308 41 41 0
CCZ1 CCZ1 P86791 Vacuolar fusion protein CCZ1 homolog chr7 Not Cancer Driver No 1 hippie, biogrid 40 43 3 3 0
CELA1 CELA1 Q9UNI1 Chymotrypsin-like elastase family member 1 chr12 Not Cancer Driver No 2 hippie, biogrid 48 20 0 0 0
CEP128_ENST00000281129 CEP128 Q6ZU80 Centrosomal protein of 128 kDa chr14 Not Cancer Driver No 1 hippie 195 897 167 167 0
CEP135 CEP135 Q66GS9 Centrosomal protein of 135 kDa chr4 Not Cancer Driver No 2 hippie, biogrid 127 690 72 72 0
CEP250 CEP250 Q9BV73 Centrosome-associated protein CEP250 chr20 Not Cancer Driver No 1 hippie 250 1859 195 195 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie, biogrid 415 288 301 301 14
DDX6 DDX6 P26196 Probable ATP-dependent RNA helicase DDX6 chr11 Census, Compendium Yes 2 intact, hippie, biogrid 44 129 7 7 5
DENND6A DENND6A Q8IWF6 Protein DENND6A chr3 Not Cancer Driver No 1 hippie, biogrid 54 69 2 2 0
DNAJB13 DNAJB13 P59910 DnaJ homolog subfamily B member 13 chr11 Not Cancer Driver No 1 hippie, biogrid 57 42 14 14 1
DPPA4 DPPA4 Q7L190 Developmental pluripotency-associated protein 4 chr3 Not Cancer Driver No 1 hippie 94 180 46 46 0
DUSP16 DUSP16 Q9BY84 Dual specificity protein phosphatase 16 chr12 Compendium Yes 1 hippie, biogrid 70 273 34 34 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 Not Cancer Driver No 1 hippie 135 447 73 73 0
DYRK1B_ENST00000323039 DYRK1B Q9Y463 Dual specificity tyrosine-phosphorylation-regulated kinase 1B chr19 Not Cancer Driver No 2 hippie, biogrid 77 319 38 38 2
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FAM184A FAM184A Q8NB25 Protein FAM184A chr6 Not Cancer Driver No 1 hippie, biogrid 197 783 129 129 0
FBXW11 FBXW11 Q9UKB1 F-box/WD repeat-containing protein 11 chr5 Not Cancer Driver No 1 hippie 75 20 3 3 7
FBXW8 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 Not Cancer Driver No 1 hippie 68 120 4 4 0
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 Not Cancer Driver No 1 hippie 71 101 10 10 0
FLOT1 FLOT1 O75955 Flotillin-1 chr6 Not Cancer Driver No 1 hippie, biogrid 43 122 15 15 0
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 Not Cancer Driver No 1 hippie, biogrid 65 288 42 42 62
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 Not Cancer Driver No 1 hippie, biogrid 86 110 26 26 50
HOOK1 HOOK1 Q9UJC3 Protein Hook homolog 1 chr1 Not Cancer Driver No 1 hippie 97 427 59 59 0
KCNE3 KCNE3 Q9Y6H6 Potassium voltage-gated channel subfamily E member 3 chr11 Not Cancer Driver No 1 hippie, biogrid 28 24 2 2 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie, biogrid 788 7 2 2 27
KRT18_ENST00000388837 KRT18 P05783 Keratin, type I cytoskeletal 18 chr12 Not Cancer Driver No 1 hippie, biogrid 57 179 21 21 4
KRT2 KRT2 P35908 Keratin, type II cytoskeletal 2 epidermal chr12 Not Cancer Driver No 1 hippie, biogrid 122 335 59 59 15
KRT8_ENST00000546897 KRT8 P05787 Keratin, type II cytoskeletal 8 chr12 Not Cancer Driver No 1 hippie, biogrid 65 221 37 37 3
LARP1 LARP1 Q6PKG0-3 Isoform 2 of La-related protein 1 chr5 Not Cancer Driver No 1 hippie 136 726 100 100 0
LATS1 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 Census, Compendium Yes 2 hippie, biogrid 161 788 100 100 0
LATS2 LATS2 Q9NRM7 Serine/threonine-protein kinase LATS2 chr13 Census, Compendium Yes 1 hippie, biogrid 178 687 116 116 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie, biogrid 86 94 13 13 1
LZTS1 LZTS1 Q9Y250 Leucine zipper putative tumor suppressor 1 chr8 Not Cancer Driver No 1 hippie, biogrid 102 467 75 75 0
LZTS2 LZTS2 Q9BRK4 Leucine zipper putative tumor suppressor 2 chr10 Not Cancer Driver No 3 hippie, biogrid 78 508 66 66 0
LZTS3_ENST00000329152 LZTS3 O60299 Leucine zipper putative tumor suppressor 3 chr20 Not Cancer Driver No 1 hippie, biogrid 72 569 62 62 0
MARS2 MARS2 Q96GW9 Methionine--tRNA ligase, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 75 34 6 6 1
MAST1 MAST1 Q9Y2H9 Microtubule-associated serine/threonine-protein kinase 1 chr19 Not Cancer Driver No 1 hippie, biogrid 204 1078 119 119 1
N4BP3 N4BP3 O15049 NEDD4-binding protein 3 chr5 Not Cancer Driver No 1 hippie, biogrid 70 474 61 61 0
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NANOG NANOG Q9H9S0 Homeobox protein NANOG chr12 Not Cancer Driver No 1 hippie 46 169 35 35 0
NIN NIN Q8N4C6 Ninein chr14 Census, Compendium Yes 1 hippie 239 1392 164 164 2
NINL NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 1 hippie 230 881 150 150 0
NRSN1 NRSN1 Q8IZ57 Neurensin-1 chr6 Not Cancer Driver No 1 hippie, biogrid 46 17 9 9 0
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 233 553 60 60 0
OCLN OCLN Q16625 Occludin chr5 Not Cancer Driver No 1 biogrid 54 244 21 21 1
ODF2 ODF2 Q5BJF6 Outer dense fiber protein 2 chr9 Not Cancer Driver No 1 hippie 123 607 90 90 0
ORC5 ORC5 O43913 Origin recognition complex subunit 5 chr7 Not Cancer Driver No 1 hippie 43 16 2 2 0
PARD3 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 Not Cancer Driver No 1 hippie, biogrid 200 1144 170 170 2
PATL1 PATL1 Q86TB9 Protein PAT1 homolog 1 chr11 Not Cancer Driver No 1 hippie 79 499 49 49 0
PCGF1 PCGF1 Q9BSM1 Polycomb group RING finger protein 1 chr2 Not Cancer Driver No 1 hippie 28 8 0 0 0
PDLIM7 PDLIM7 Q9NR12 PDZ and LIM domain protein 7 chr5 Not Cancer Driver No 1 hippie, biogrid 48 244 20 20 0
PFN1 PFN1 P07737 Profilin-1 chr17 Not Cancer Driver No 1 hippie, biogrid 16 7 1 1 3
POMGNT2_ENST00000441964 POMGNT2 Q8NAT1 Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 chr3 Not Cancer Driver No 1 hippie, biogrid 65 23 6 6 3
POU5F1 POU5F1 Q01860 POU domain, class 5, transcription factor 1 chr6 Census Yes 1 hippie 36 186 12 12 0
PRG2 PRG2 P13727 Bone marrow proteoglycan chr11 Not Cancer Driver No 3 hippie, biogrid 45 65 15 15 0
PROZ_ENST00000375547 PROZ P22891 Vitamin K-dependent protein Z chr13 Not Cancer Driver No 2 hippie, biogrid 41 13 3 3 0
PTPN18 PTPN18 Q99952 Tyrosine-protein phosphatase non-receptor type 18 chr2 Not Cancer Driver No 1 hippie 51 138 8 8 0
PXN_ENST00000228307 PXN P49023 Paxillin chr12 Not Cancer Driver No 1 hippie, biogrid 62 341 24 24 0
RACGAP1_ENST00000454520 RACGAP1 Q9H0H5 Rac GTPase-activating protein 1 chr12 Not Cancer Driver No 1 hippie, biogrid 74 255 27 27 0
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 Not Cancer Driver No 1 hippie, biogrid 52 19 2 2 0
RNF20 RNF20 Q5VTR2 E3 ubiquitin-protein ligase BRE1A chr9 Not Cancer Driver No 1 hippie, biogrid 126 561 64 64 0
RPGRIP1L_ENST00000379925 RPGRIP1L Q68CZ1 Protein fantom chr16 Not Cancer Driver No 1 hippie 177 586 94 94 8
RPL28_ENST00000559463 RPL28 P46779 60S ribosomal protein L28 chr19 Not Cancer Driver No 1 hippie, biogrid 29 115 24 24 0
SAMD4B SAMD4B Q5PRF9 Protein Smaug homolog 2 chr19 Not Cancer Driver No 1 hippie 79 467 57 57 0
SASS6 SASS6 Q6UVJ0 Spindle assembly abnormal protein 6 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 82 331 37 37 1
SF3B2 SF3B2 Q13435 Splicing factor 3B subunit 2 chr11 Not Cancer Driver No 1 hippie 110 804 105 105 0
SIPA1L1 SIPA1L1 O43166 Signal-induced proliferation-associated 1-like protein 1 chr14 Not Cancer Driver No 1 hippie, biogrid 321 1175 226 226 0
SIPA1L3 SIPA1L3 O60292 Signal-induced proliferation-associated 1-like protein 3 chr19 Not Cancer Driver No 1 hippie, biogrid 273 1257 190 190 0
SIPA1_ENST00000534313 SIPA1 Q96FS4 Signal-induced proliferation-associated protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 67 666 43 43 0
SNX5_ENST00000377759 SNX5 Q9Y5X3 Sorting nexin-5 chr20 Not Cancer Driver No 1 hippie, biogrid 33 91 13 13 0
SSX2IP SSX2IP Q9Y2D8 Afadin- and alpha-actinin-binding protein chr1 Not Cancer Driver No 1 hippie 82 265 31 31 0
STIL_ENST00000360380 STIL Q15468 SCL-interrupting locus protein chr1 Census, Compendium Yes 1 hippie, biogrid 147 735 85 85 1
STX7 STX7 O15400 Syntaxin-7 chr6 Not Cancer Driver No 1 hippie, biogrid 29 164 14 14 0
SYNE3 SYNE3 Q6ZMZ3 Nesprin-3 chr14 Not Cancer Driver No 1 hippie, biogrid 143 236 42 42 0
TCEANC_ENST00000380600 TCEANC Q8N8B7 Transcription elongation factor A N-terminal and central domain-containing protein chrX Not Cancer Driver No 1 intact, hippie 38 138 12 12 0
TGM2 TGM2 P21980 Protein-glutamine gamma-glutamyltransferase 2 chr20 Not Cancer Driver No 1 hippie 123 107 26 26 0
TOMM22 TOMM22 Q9NS69 Mitochondrial import receptor subunit TOM22 homolog chr22 Not Cancer Driver No 1 hippie, biogrid 18 83 9 9 0
TRIM52 TRIM52 Q96A61 E3 ubiquitin-protein ligase TRIM52 chr5 Not Cancer Driver No 1 hippie, biogrid 23 147 13 13 0
TRIM66_ENST00000299550 TRIM66 O15016 Tripartite motif-containing protein 66 chr11 Not Cancer Driver No 1 hippie 58 723 32 32 0
TSPYL1 TSPYL1 Q9H0U9 Testis-specific Y-encoded-like protein 1 chr6 Not Cancer Driver No 2 hippie, biogrid 48 239 31 31 0
UBR1 UBR1 Q8IWV7 E3 ubiquitin-protein ligase UBR1 chr15 Not Cancer Driver No 1 hippie, biogrid 170 165 15 15 18
UNC119 UNC119 Q13432 Protein unc-119 homolog A chr17 Not Cancer Driver No 1 hippie, biogrid 20 89 4 4 1
UNC119B UNC119B A6NIH7 Protein unc-119 homolog B chr12 Not Cancer Driver No 1 hippie, biogrid 35 71 4 4 0
VASP VASP P50552 Vasodilator-stimulated phosphoprotein chr19 Not Cancer Driver No 1 hippie, biogrid 39 335 34 34 0
VCL VCL P18206 Vinculin chr10 Not Cancer Driver No 1 hippie, biogrid 114 673 80 80 2
VIM_ENST00000224237 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 hippie, biogrid 84 316 57 57 1
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 2 hippie, biogrid 22 109 4 4 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 2 hippie, biogrid 26 77 9 9 2
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 2 hippie, biogrid 15 55 3 3 0
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 2 hippie, biogrid 29 41 6 6 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 2 hippie, biogrid 30 81 10 10 0
ZYX ZYX Q15942 Zyxin chr7 Not Cancer Driver No 1 hippie, biogrid 83 385 52 52 0