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SIKE1_ENST00000060969 ,SIKE1 ,Q9BRV8
  • Uniprot Accession= Q9BRV8
  • Ensembl Transcript= ENST00000060969.5
  • Uniprot Name= SIKE1
  • Name= Suppressor of IKBKE 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 32
  • Number of Interaction partner in biogrid: 36
  • Number of Interaction partner in hippie: 59
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABI2_ENST00000261018 ABI2 Q9NYB9 Abl interactor 2 chr2 Not Cancer Driver No 1 hippie, biogrid 56 361 38 38 0
AGGF1 AGGF1 Q8N302 Angiogenic factor with G patch and FHA domains 1 chr5 Not Cancer Driver No 1 hippie 100 582 80 80 1
ALDH7A1 ALDH7A1 P49419 Alpha-aminoadipic semialdehyde dehydrogenase chr5 Not Cancer Driver No 1 hippie, biogrid 52 26 1 1 8
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie 34 103 14 14 0
ASH1L_ENST00000368346 ASH1L Q9NR48 Histone-lysine N-methyltransferase ASH1L chr1 Not Cancer Driver No 1 hippie 415 1858 256 256 1
BTD_ENST00000643237 BTD P43251 Biotinidase chr3 Not Cancer Driver No 1 intact, hippie 63 13 1 1 9
CBFA2T2 CBFA2T2 O43439 Protein CBFA2T2 chr20 Not Cancer Driver No 1 intact, hippie 89 457 58 58 0
CCDC186 CCDC186 Q7Z3E2 Coiled-coil domain-containing protein 186 chr10 Not Cancer Driver No 1 hippie, biogrid 99 702 80 80 0
CCDC88C CCDC88C Q9P219 Protein Daple chr14 Not Cancer Driver No 1 hippie, biogrid 270 1604 225 225 1
CDC42BPB CDC42BPB Q9Y5S2 Serine/threonine-protein kinase MRCK beta chr14 Not Cancer Driver No 1 hippie, biogrid 185 696 92 92 0
CENPQ CENPQ Q7L2Z9 Centromere protein Q chr6 Not Cancer Driver No 1 intact, hippie 33 183 23 23 0
ELL ELL P55199 RNA polymerase II elongation factor ELL chr19 Census, Compendium Yes 1 intact, hippie 67 446 53 53 0
EMD EMD P50402 Emerin chrX Not Cancer Driver No 1 hippie 42 160 28 28 4
EXOC1 EXOC1 Q9NV70 Exocyst complex component 1 chr4 Not Cancer Driver No 2 hippie, biogrid 128 154 22 22 0
EXOC4 EXOC4 Q96A65 Exocyst complex component 4 chr7 Not Cancer Driver No 1 hippie, biogrid 164 133 33 33 0
FGFR1OP2 FGFR1OP2 Q9NVK5 FGFR1 oncogene partner 2 chr12 Not Cancer Driver No 3 intact, hippie, biogrid 25 185 21 21 0
ICE2 ICE2 Q659A1 Little elongation complex subunit 2 chr15 Not Cancer Driver No 1 intact, hippie 107 399 45 45 0
IFT20_ENST00000395418 IFT20 Q8IY31 Intraflagellar transport protein 20 homolog chr17 Not Cancer Driver No 1 hippie, biogrid 11 0 0 0 0
IKBKE IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 Not Cancer Driver No 1 hippie 108 76 13 13 0
ISCA2 ISCA2 Q86U28 Iron-sulfur cluster assembly 2 homolog, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 13 38 3 3 1
KIF2B KIF2B Q8N4N8 Kinesin-like protein KIF2B chr17 Not Cancer Driver No 2 hippie, biogrid 314 189 116 116 0
MAP4K4_ENST00000347699 MAP4K4 O95819 Mitogen-activated protein kinase kinase kinase kinase 4 chr2 Not Cancer Driver No 1 hippie 143 649 55 55 0
MOB4 MOB4 Q9Y3A3 MOB-like protein phocein chr2 Not Cancer Driver No 4 intact, hippie, biogrid 23 34 5 5 0
MRPL58 MRPL58 Q14197 Peptidyl-tRNA hydrolase ICT1, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 28 105 13 13 0
NHSL2 NHSL2 Q5HYW2 NHS-like protein 2 chrX Not Cancer Driver No 2 hippie, biogrid 123 1127 119 119 0
PDCD10_ENST00000473645 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 32 25 4 4 0
PLP1 PLP1 P60201 Myelin proteolipid protein chrX Not Cancer Driver No 1 hippie, biogrid 49 5 1 1 72
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 Not Cancer Driver No 4 intact, hippie 41 12 1 1 8
PPP2CB PPP2CB P62714 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform chr8 Not Cancer Driver No 5 intact, hippie, biogrid 37 12 0 0 0
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 Census, Compendium Yes 4 intact, hippie, biogrid 179 0 0 0 4
PPP2R1B_ENST00000527614 PPP2R1B P30154 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform chr11 Not Cancer Driver No 2 intact, hippie 72 17 1 1 0
PSMC5 PSMC5 P62195 26S proteasome regulatory subunit 8 chr17 Not Cancer Driver No 2 hippie, biogrid 52 64 6 6 0
RABEP2 RABEP2 Q9H5N1 Rab GTPase-binding effector protein 2 chr16 Not Cancer Driver No 1 hippie, biogrid 87 441 71 71 0
RASIP1 RASIP1 Q5U651 Ras-interacting protein 1 chr19 Not Cancer Driver No 1 intact, hippie 73 505 48 48 0
RASSF3_ENST00000336061 RASSF3 Q86WH2 Ras association domain-containing protein 3 chr12 Not Cancer Driver No 1 intact, hippie 21 59 3 3 0
S100A6_ENST00000496817 S100A6 P06703 Protein S100-A6 chr1 Not Cancer Driver No 1 hippie, biogrid 5 4 0 0 0
SCOC SCOC Q9UIL1 Short coiled-coil protein chr4 Not Cancer Driver No 1 intact, hippie 13 82 8 8 0
SIKE1_ENST00000060969 SIKE1 Q9BRV8 Suppressor of IKBKE 1 chr1 Not Cancer Driver No 2 intact, hippie 23 107 9 9 0
SLMAP SLMAP Q14BN4 Sarcolemmal membrane-associated protein chr3 Not Cancer Driver No 5 intact, hippie, biogrid 77 464 38 38 0
STK24 STK24 Q9Y6E0 Serine/threonine-protein kinase 24 chr13 Not Cancer Driver No 4 intact, hippie, biogrid 67 118 16 16 0
STK25 STK25 O00506 Serine/threonine-protein kinase 25 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 42 170 15 15 0
STK26 STK26 Q9P289 Serine/threonine-protein kinase 26 chrX Not Cancer Driver No 3 intact, hippie, biogrid 62 119 18 18 0
STRIP1 STRIP1 Q5VSL9 Striatin-interacting protein 1 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 97 267 33 33 0
STRIP2 STRIP2 Q9ULQ0 Striatin-interacting protein 2 chr7 Not Cancer Driver No 3 intact, hippie, biogrid 115 177 21 21 0
STRN STRN O43815 Striatin chr2 Census, Compendium Yes 5 intact, hippie, biogrid 97 348 43 43 0
STRN3 STRN3 Q13033 Striatin-3 chr14 Not Cancer Driver No 5 intact, hippie, biogrid 93 366 42 42 0
STRN4_ENST00000263280 STRN4 Q9NRL3 Striatin-4 chr19 Not Cancer Driver No 2 hippie, biogrid 84 407 40 40 0
STX11 STX11 O75558 Syntaxin-11 chr6 Not Cancer Driver No 3 intact, hippie, biogrid 71 48 7 7 0
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 Not Cancer Driver No 1 hippie 101 42 5 5 12
TNFRSF1A TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 Not Cancer Driver No 2 hippie, biogrid 58 111 15 15 12
TNIK TNIK Q9UKE5 TRAF2 and NCK-interacting protein kinase chr3 Not Cancer Driver No 1 intact, hippie, biogrid 254 781 156 156 0
TRAF3IP3 TRAF3IP3 Q9Y228 TRAF3-interacting JNK-activating modulator chr1 Not Cancer Driver No 3 hippie, biogrid 90 347 63 63 0
TRIML2 TRIML2 Q8N7C3 Probable E3 ubiquitin-protein ligase TRIML2 chr4 Not Cancer Driver No 2 hippie, biogrid 165 77 28 28 0
TTC1 TTC1 Q99614 Tetratricopeptide repeat protein 1 chr5 Not Cancer Driver No 1 intact, hippie 28 211 21 21 0
TXLNA_ENST00000373610 TXLNA P40222 Alpha-taxilin chr1 Not Cancer Driver No 1 intact, hippie 68 481 59 59 0
TXLNB TXLNB Q8N3L3 Beta-taxilin chr6 Not Cancer Driver No 1 intact, hippie 131 546 115 115 0
WDYHV1 NTAQ1 Q96HA8 Protein N-terminal glutamine amidohydrolase chr8 Not Cancer Driver No 1 intact 38 26 3 3 0
ZC2HC1C ZC2HC1C Q53FD0 Zinc finger C2HC domain-containing protein 1C chr14 Not Cancer Driver No 2 intact, hippie, biogrid 39 395 32 32 0
ZRANB1 ZRANB1 Q9UGI0 Ubiquitin thioesterase ZRANB1 chr10 Not Cancer Driver No 1 hippie 87 158 25 25 0
ZYG11A ZYG11A Q6WRX3 Protein zyg-11 homolog A chr1 Not Cancer Driver No 1 hippie, biogrid 52 7 0 0 0