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SHC1_ENST00000368445 ,SHC1 ,P29353
  • Uniprot Accession= P29353
  • Ensembl Transcript= ENST00000368445.9
  • Uniprot Name= SHC1
  • Name= SHC-transforming protein 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 115
  • Number of Interaction partner in biogrid: 36
  • Number of Interaction partner in hippie: 354
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 56 28 6 6 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 Census, Compendium Yes 1 hippie 139 604 73 73 2
ACLY_ENST00000590151 ACLY P53396 ATP-citrate synthase chr17 Not Cancer Driver No 2 intact, hippie 120 114 12 12 0
ACOT9_ENST00000336430 ACOT9 Q9Y305 Acyl-coenzyme A thioesterase 9, mitochondrial chrX Not Cancer Driver No 1 intact, hippie 45 45 3 3 0
ACTA1 ACTA1 P68133 Actin, alpha skeletal muscle chr1 Not Cancer Driver No 1 hippie 70 48 14 14 84
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie 112 43 5 5 5
ACTG1_ENST00000575087 ACTG1 P63261 Actin, cytoplasmic 2 chr17 Not Cancer Driver No 1 hippie 73 42 10 10 16
ACTN4 ACTN4 O43707 Alpha-actinin-4 chr19 Not Cancer Driver No 1 hippie 131 244 42 42 8
AFDN_ENST00000447894 AFDN P55196 Afadin chr6 Census Yes 1 hippie 248 1247 180 180 0
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX Not Cancer Driver No 1 hippie 88 166 22 22 11
AKAP12 AKAP12 Q02952 A-kinase anchor protein 12 chr6 Not Cancer Driver No 1 intact, hippie 215 1770 214 214 0
ALDH6A1 ALDH6A1 Q02252 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial chr14 Not Cancer Driver No 1 hippie 54 83 11 11 1
ALK ALK Q9UM73 ALK tyrosine kinase receptor chr2 Census, Compendium Yes 3 intact, hippie, biogrid 303 575 114 114 16
AMD1 AMD1 P17707 S-adenosylmethionine decarboxylase proenzyme chr6 Not Cancer Driver No 2 hippie, biogrid 42 9 1 1 0
ANKS1A ANKS1A Q92625 Ankyrin repeat and SAM domain-containing protein 1A chr6 Not Cancer Driver No 1 hippie 120 756 75 75 0
ANKS1B ANKS1B Q7Z6G8 Ankyrin repeat and sterile alpha motif domain-containing protein 1B chr12 Not Cancer Driver No 1 intact, hippie 254 659 150 150 0
ANP32B ANP32B Q92688 Acidic leucine-rich nuclear phosphoprotein 32 family member B chr9 Not Cancer Driver No 1 hippie 22 117 12 12 0
ANXA2_ENST00000396024 ANXA2 P07355 Annexin A2 chr15 Not Cancer Driver No 1 hippie 49 20 4 4 0
AP1B1 AP1B1 Q10567 AP-1 complex subunit beta-1 chr22 Not Cancer Driver No 1 intact, hippie, biogrid 114 119 10 10 1
AP2A1 AP2A1 O95782 AP-2 complex subunit alpha-1 chr19 Not Cancer Driver No 6 intact, hippie, biogrid 95 188 12 12 0
AP2A2_ENST00000448903 AP2A2 O94973 AP-2 complex subunit alpha-2 chr11 Not Cancer Driver No 4 intact, hippie 100 145 12 12 0
AP2B1_ENST00000621914 AP2B1 P63010 AP-2 complex subunit beta chr17 Not Cancer Driver No 2 intact, hippie 85 95 12 12 0
AP2M1_ENST00000292807 AP2M1 Q96CW1 AP-2 complex subunit mu chr3 Not Cancer Driver No 1 hippie 55 41 9 9 1
AP2S1_ENST00000263270 AP2S1 P53680 AP-2 complex subunit sigma chr19 Not Cancer Driver No 1 hippie 4 0 0 0 3
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 2 intact, hippie 128 418 71 71 17
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie, biogrid 196 443 88 88 169
ARAP1 ARAP1 Q96P48 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 chr11 Not Cancer Driver No 1 hippie 152 401 28 28 0
ARHGAP32 ARHGAP32 A7KAX9 Rho GTPase-activating protein 32 chr11 Not Cancer Driver No 1 hippie 268 1476 193 193 0
ARHGEF3_ENST00000296315 ARHGEF3 Q9NR81 Rho guanine nucleotide exchange factor 3 chr3 Not Cancer Driver No 1 hippie 70 154 17 17 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 Not Cancer Driver No 1 hippie 170 1141 127 127 0
ATAD3B ATAD3B Q5T9A4 ATPase family AAA domain-containing protein 3B chr1 Not Cancer Driver No 1 hippie 84 243 19 19 0
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 Not Cancer Driver No 1 hippie 168 341 64 64 0
BCL3 BCL3 P20749 B-cell lymphoma 3 protein chr19 Census Yes 1 hippie 44 259 23 23 0
BCR BCR P11274 Breakpoint cluster region protein chr22 Census, Compendium Yes 1 hippie 146 603 69 69 0
BLNK BLNK Q8WV28 B-cell linker protein chr10 Not Cancer Driver No 1 hippie 74 376 61 61 0
BRCC3 BRCC3 P46736 Lys-63-specific deubiquitinase BRCC36 chrX Not Cancer Driver No 1 intact, hippie 39 74 7 7 0
BUB1 BUB1 O43683 Mitotic checkpoint serine/threonine-protein kinase BUB1 chr2 Not Cancer Driver No 1 hippie 139 466 64 64 0
C11orf58 SMAP O00193 Small acidic protein chr11 Not Cancer Driver No 1 intact 22 183 22 22 0
CAD CAD P27708 CAD protein chr2 Not Cancer Driver No 1 intact, hippie 287 368 52 52 1
CALCOCO2_ENST00000258947 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 Not Cancer Driver No 2 intact, hippie 42 212 19 19 0
CALD1 CALD1 Q05682 Caldesmon chr7 Not Cancer Driver No 1 hippie 133 793 133 133 0
CAMK2A_ENST00000348628 CAMK2A Q9UQM7 Calcium/calmodulin-dependent protein kinase type II subunit alpha chr5 Not Cancer Driver No 1 intact, hippie 83 62 10 10 7
CAPNS1 CAPNS1 P04632 Calpain small subunit 1 chr19 Not Cancer Driver No 1 hippie 30 58 5 5 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 Census, Compendium Yes 1 hippie 115 512 56 56 4
CBLB CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 Census Yes 1 hippie 160 562 104 104 0
CBLC_ENST00000647358 CBLC Q9ULV8 E3 ubiquitin-protein ligase CBL-C chr19 Census Yes 1 intact, hippie 60 128 21 21 0
CCT2 CCT2 P78371 T-complex protein 1 subunit beta chr12 Not Cancer Driver No 1 hippie 63 46 3 3 0
CCT6A CCT6A P40227 T-complex protein 1 subunit zeta chr7 Not Cancer Driver No 1 hippie 66 5 1 1 0
CD22 CD22 P20273 B-cell receptor CD22 chr19 Not Cancer Driver No 1 hippie 173 290 66 66 0
CD247 CD247 P20963 T-cell surface glycoprotein CD3 zeta chain chr1 Not Cancer Driver No 1 hippie 33 91 24 24 0
CD3D CD3D P04234 T-cell surface glycoprotein CD3 delta chain chr11 Not Cancer Driver No 1 hippie 23 2 1 1 0
CD3E CD3E P07766 T-cell surface glycoprotein CD3 epsilon chain chr11 Not Cancer Driver No 1 intact, hippie 28 72 12 12 0
CD3G CD3G P09693 T-cell surface glycoprotein CD3 gamma chain chr11 Not Cancer Driver No 1 hippie 25 48 7 7 0
CD81 CD81 P60033 CD81 antigen chr11 Not Cancer Driver No 1 hippie 28 0 0 0 0
CDC25C CDC25C P30307 M-phase inducer phosphatase 3 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 61 224 26 26 0
CDC5L CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 intact, hippie 100 618 77 77 0
CDH5 CDH5 P33151 Cadherin-5 chr16 Not Cancer Driver No 1 intact, hippie 144 305 55 55 0
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 Not Cancer Driver No 1 intact, hippie 64 241 25 25 0
CEP170 CEP170 Q5SW79 Centrosomal protein of 170 kDa chr1 Not Cancer Driver No 1 intact, hippie 264 1429 246 246 0
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 Not Cancer Driver No 1 hippie 25 201 22 22 2
CIPC CIPC Q9C0C6 CLOCK-interacting pacemaker chr14 Not Cancer Driver No 1 hippie 43 354 41 41 0
CLIC4 CLIC4 Q9Y696 Chloride intracellular channel protein 4 chr1 Not Cancer Driver No 1 hippie, biogrid 24 49 4 4 0
CLTC_ENST00000269122 CLTC Q00610 Clathrin heavy chain 1 chr17 Census, Compendium Yes 1 hippie 190 71 6 6 1
CORO1C_ENST00000541050 CORO1C Q9ULV4 Coronin-1C chr12 Not Cancer Driver No 1 hippie 61 84 13 13 0
CORO2B CORO2B Q9UQ03 Coronin-2B chr15 Not Cancer Driver No 2 intact, hippie, biogrid 85 37 7 7 0
CRK CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 1 hippie 30 197 23 23 0
CRKL CRKL P46109 Crk-like protein chr22 Not Cancer Driver No 1 hippie 38 160 25 25 0
CS CS O75390 Citrate synthase, mitochondrial chr12 Not Cancer Driver No 2 hippie, biogrid 50 13 2 2 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 Census Yes 1 hippie 133 124 17 17 20
CSF2RB CSF2RB P32927 Cytokine receptor common subunit beta chr22 Not Cancer Driver No 2 intact, hippie 204 541 120 120 0
CSF3R_ENST00000361632 CSF3R Q99062 Granulocyte colony-stimulating factor receptor chr1 Census, Compendium Yes 1 hippie 131 209 34 34 2
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 Not Cancer Driver No 2 intact, hippie 41 18 1 1 0
CUL9 CUL9 Q8IWT3 Cullin-9 chr6 Not Cancer Driver No 1 hippie, biogrid 321 633 73 73 0
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 Not Cancer Driver No 1 hippie 102 485 61 61 4
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 Not Cancer Driver No 1 intact 126 50 8 8 4
DDR1_ENST00000324771 DDR1 Q08345 Epithelial discoidin domain-containing receptor 1 chr6 Not Cancer Driver No 1 hippie 123 253 49 49 0
DDR2 DDR2 Q16832 Discoidin domain-containing receptor 2 chr1 Census Yes 1 hippie 192 118 34 34 7
DDX19B DDX19B Q9UMR2 ATP-dependent RNA helicase DDX19B chr16 Not Cancer Driver No 1 hippie, biogrid 44 113 9 9 0
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 Census Yes 1 hippie 74 225 23 23 0
DNAJA1 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 Not Cancer Driver No 1 hippie 37 153 16 16 0
DNAJA2 DNAJA2 O60884 DnaJ homolog subfamily A member 2 chr16 Not Cancer Driver No 1 intact, hippie 50 174 27 27 0
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 Census Yes 1 intact, hippie 138 270 43 43 22
DOK1 DOK1 Q99704 Docking protein 1 chr2 Not Cancer Driver No 1 hippie 50 294 31 31 0
DOK2 DOK2 O60496 Docking protein 2 chr8 Not Cancer Driver No 1 hippie 58 254 31 31 0
DUSP23_ENST00000368109 DUSP23 Q9BVJ7 Dual specificity protein phosphatase 23 chr1 Not Cancer Driver No 1 hippie 6 13 1 1 0
EEF2 EEF2 P13639 Elongation factor 2 chr19 Not Cancer Driver No 1 intact, hippie 111 78 14 14 1
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EGF EGF P01133 Pro-epidermal growth factor chr4 Not Cancer Driver No 1 hippie 184 191 25 25 1
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 2 hippie, biogrid 444 223 35 35 1
EIF4G3_ENST00000264211 EIF4G3 O43432 Eukaryotic translation initiation factor 4 gamma 3 chr1 Not Cancer Driver No 1 hippie 200 1018 127 127 0
ELP1 ELP1 O95163 Elongator complex protein 1 chr9 Not Cancer Driver No 1 intact, hippie 143 157 23 23 2
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 Compendium Yes 1 hippie 171 187 39 39 3
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 Not Cancer Driver No 1 intact 182 140 24 24 0
EPOR EPOR P19235 Erythropoietin receptor chr19 Not Cancer Driver No 1 hippie 41 120 11 11 1
EPS8_ENST00000645775 EPS8 Q12929 Epidermal growth factor receptor kinase substrate 8 chr12 Not Cancer Driver No 1 hippie 106 459 54 54 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 2 hippie, biogrid 275 314 41 41 1
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 Census, Compendium Yes 2 hippie, biogrid 298 396 70 70 3
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 Census, Compendium Yes 4 intact, hippie, biogrid 428 323 116 116 2
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 Not Cancer Driver No 1 intact, hippie 55 297 37 37 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 2 intact, hippie 121 195 27 27 2
EZR EZR P15311 Ezrin chr6 Census Yes 1 intact, hippie 66 295 35 35 0
FAM118B FAM118B Q9BPY3 Protein FAM118B chr11 Not Cancer Driver No 1 intact, hippie 50 37 4 4 0
FASN FASN P49327 Fatty acid synthase chr17 Not Cancer Driver No 1 hippie 291 309 42 42 0
FASTKD3 FASTKD3 Q14CZ7 FAST kinase domain-containing protein 3, mitochondrial chr5 Not Cancer Driver No 1 intact, hippie 106 6 1 1 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 intact, hippie 322 230 38 38 0
FCGR1A FCGR1A P12314 High affinity immunoglobulin gamma Fc receptor I chr1 Not Cancer Driver No 1 intact, hippie 62 37 5 5 0
FCGR2A FCGR2A P12318 Low affinity immunoglobulin gamma Fc region receptor II-a chr1 Not Cancer Driver No 1 hippie 64 133 28 28 0
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 Census Yes 2 intact, hippie 51 99 30 30 0
FCGR3A_ENST00000443193 FCGR3A P08637 Low affinity immunoglobulin gamma Fc region receptor III-A chr1 Not Cancer Driver No 1 hippie 69 0 0 0 1
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 Census, Compendium Yes 1 hippie 152 230 43 43 74
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 Census, Compendium Yes 1 hippie 238 228 44 44 72
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 Census, Compendium Yes 1 intact 113 162 28 28 0
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 Not Cancer Driver No 1 hippie 299 103 20 20 0
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 Census, Compendium Yes 1 hippie 253 259 41 41 13
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 92 70 13 13 0
GAB1_ENST00000262994 GAB1 Q13480 GRB2-associated-binding protein 1 chr4 Not Cancer Driver No 2 hippie, biogrid 79 570 68 68 1
GAB2 GAB2 Q9UQC2 GRB2-associated-binding protein 2 chr11 Not Cancer Driver No 1 hippie 85 537 73 73 0
GAP43_ENST00000305124 GAP43 P17677 Neuromodulin chr3 Not Cancer Driver No 1 hippie 79 238 79 79 0
GAREM1 GAREM1 Q9H706 GRB2-associated and regulator of MAPK protein 1 chr18 Not Cancer Driver No 2 intact, hippie 128 408 50 50 0
GBF1 GBF1 Q92538 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 chr10 Not Cancer Driver No 1 hippie 216 669 76 76 0
GEMIN7_ENST00000591607 GEMIN7 Q9H840 Gem-associated protein 7 chr19 Not Cancer Driver No 1 hippie 32 48 7 7 0
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 Not Cancer Driver No 1 hippie 65 288 42 42 62
GH1 GH1 P01241 Somatotropin chr17 Not Cancer Driver No 1 hippie 54 24 9 9 15
GHR_ENST00000612382 GHR P10912 Growth hormone receptor chr5 Not Cancer Driver No 1 hippie 173 229 66 66 19
GRAP GRAP Q13588 GRB2-related adapter protein chr17 Not Cancer Driver No 1 intact, hippie 10 0 0 0 1
GRAP2_ENST00000407075 GRAP2 O75791 GRB2-related adapter protein 2 chr22 Not Cancer Driver No 1 hippie 59 151 20 20 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 24 intact, hippie, biogrid 28 10 1 1 0
GRB7_ENST00000394209 GRB7 Q14451 Growth factor receptor-bound protein 7 chr17 Not Cancer Driver No 1 hippie 84 134 27 27 0
GRN GRN P28799 Progranulin chr17 Not Cancer Driver No 1 hippie 76 29 6 6 1
GRPEL1 GRPEL1 Q9HAV7 GrpE protein homolog 1, mitochondrial chr4 Not Cancer Driver No 1 hippie 22 88 7 7 0
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 Not Cancer Driver No 1 hippie 44 219 32 32 2
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 1 hippie 182 749 132 132 0
HDGFL3 HDGFL3 Q9Y3E1 Hepatoma-derived growth factor-related protein 3 chr15 Not Cancer Driver No 1 hippie 25 163 18 18 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 Census Yes 1 hippie 118 435 51 51 0
HMOX2_ENST00000406590 HMOX2 P30519 Heme oxygenase 2 chr16 Not Cancer Driver No 1 intact, hippie 27 74 10 10 0
HNRNPA2B1 HNRNPA2B1 P22626 Heterogeneous nuclear ribonucleoproteins A2/B1 chr7 Census, Compendium Yes 1 intact, hippie 68 255 41 41 0
HNRNPC_ENST00000420743 HNRNPC P07910 Heterogeneous nuclear ribonucleoproteins C1/C2 chr14 Not Cancer Driver No 1 intact, hippie 42 227 35 35 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 Not Cancer Driver No 1 hippie 77 504 45 45 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 hippie 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 hippie 100 254 43 43 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie 24 200 13 13 0
HSPA1L HSPA1L P34931 Heat shock 70 kDa protein 1-like chr6 Not Cancer Driver No 1 hippie 119 141 28 28 0
HSPA4 HSPA4 P34932 Heat shock 70 kDa protein 4 chr5 Not Cancer Driver No 1 intact, hippie 80 351 24 24 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 2 intact, hippie 73 282 35 35 0
HSPA6 HSPA6 P17066 Heat shock 70 kDa protein 6 chr1 Not Cancer Driver No 1 hippie 112 235 27 27 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 2 intact, hippie 149 251 52 52 0
HSPA9 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 2 intact, hippie 67 283 26 26 2
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 Not Cancer Driver No 1 intact, hippie 10 118 8 8 20
HSPH1_ENST00000320027 HSPH1 Q92598 Heat shock protein 105 kDa chr13 Not Cancer Driver No 1 intact, hippie 103 323 42 42 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 Not Cancer Driver No 1 hippie 183 265 37 37 6
IL2 IL2 P60568 Interleukin-2 chr4 Census Yes 1 hippie 24 6 1 1 0
IL2RB IL2RB P14784 Interleukin-2 receptor subunit beta chr22 Not Cancer Driver No 1 hippie 81 182 33 33 1
IL2RG IL2RG P31785 Cytokine receptor common subunit gamma chrX Not Cancer Driver No 1 hippie 56 32 6 6 33
IL4R_ENST00000543915 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 Not Cancer Driver No 1 hippie 133 420 64 64 0
IL6ST_ENST00000336909 IL6ST P40189 Interleukin-6 receptor subunit beta chr5 Census, Compendium Yes 1 hippie 102 315 40 40 2
ILK_ENST00000299421 ILK Q13418 Integrin-linked protein kinase chr11 Not Cancer Driver No 1 hippie 45 71 9 9 0
INPP5D INPP5D Q92835 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 chr2 Not Cancer Driver No 2 intact, hippie 176 578 90 90 0
INPPL1 INPPL1 O15357 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 chr11 Not Cancer Driver No 2 intact, hippie 174 566 76 76 4
INSR INSR P06213 Insulin receptor chr19 Not Cancer Driver No 3 intact, hippie 190 280 57 57 64
IPO4 IPO4 Q8TEX9 Importin-4 chr14 Not Cancer Driver No 1 intact, hippie 106 87 5 5 0
IPO7 IPO7 O95373 Importin-7 chr11 Not Cancer Driver No 1 hippie 138 202 30 30 0
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 Not Cancer Driver No 1 intact, hippie 183 351 35 35 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 Not Cancer Driver No 1 hippie 161 1072 133 133 2
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 Not Cancer Driver No 1 hippie 69 1112 57 57 0
ITGAV ITGAV P06756 Integrin alpha-V chr2 Census Yes 1 hippie 153 92 9 9 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 Not Cancer Driver No 1 hippie 103 84 10 10 0
ITGB3 ITGB3 P05106 Integrin beta-3 chr17 Not Cancer Driver No 1 hippie 124 66 5 5 30
ITGB4 ITGB4 P16144 Integrin beta-4 chr17 Not Cancer Driver No 1 hippie 248 753 86 86 14
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 Census, Compendium Yes 1 hippie 136 59 5 5 5
JUP JUP P14923 Junction plakoglobin chr17 Not Cancer Driver No 1 intact, hippie 112 241 37 37 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 Not Cancer Driver No 1 hippie 67 291 28 28 3
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 Census, Compendium Yes 1 hippie 357 275 55 55 2
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 Census, Compendium Yes 1 hippie, biogrid 226 83 33 33 21
KRT1 KRT1 P04264 Keratin, type II cytoskeletal 1 chr12 Not Cancer Driver No 1 hippie 133 426 98 98 20
KRT10 KRT10 P13645 Keratin, type I cytoskeletal 10 chr17 Not Cancer Driver No 1 hippie 79 297 38 38 16
KRT13 KRT13 P13646 Keratin, type I cytoskeletal 13 chr17 Not Cancer Driver No 1 hippie 90 180 29 29 5
KRT14 KRT14 P02533 Keratin, type I cytoskeletal 14 chr17 Not Cancer Driver No 1 hippie 76 183 31 31 40
KRT16 KRT16 P08779 Keratin, type I cytoskeletal 16 chr17 Not Cancer Driver No 1 hippie 83 152 28 28 16
KRT17 KRT17 Q04695 Keratin, type I cytoskeletal 17 chr17 Not Cancer Driver No 1 hippie 86 160 31 31 18
KRT18_ENST00000388837 KRT18 P05783 Keratin, type I cytoskeletal 18 chr12 Not Cancer Driver No 1 intact, hippie 57 179 21 21 4
KRT2 KRT2 P35908 Keratin, type II cytoskeletal 2 epidermal chr12 Not Cancer Driver No 1 hippie 122 335 59 59 15
KRT3 KRT3 P12035 Keratin, type II cytoskeletal 3 chr12 Not Cancer Driver No 1 hippie 119 218 38 38 2
KRT4 KRT4 P19013 Keratin, type II cytoskeletal 4 chr12 Not Cancer Driver No 1 hippie 116 130 23 23 1
KRT5 KRT5 P13647 Keratin, type II cytoskeletal 5 chr12 Not Cancer Driver No 1 hippie 112 193 47 47 50
KRT6A KRT6A P02538 Keratin, type II cytoskeletal 6A chr12 Not Cancer Driver No 1 hippie 127 138 35 35 24
KRT77 KRT77 Q7Z794 Keratin, type II cytoskeletal 1b chr12 Not Cancer Driver No 1 hippie 82 233 38 38 0
KRT9 KRT9 P35527 Keratin, type I cytoskeletal 9 chr17 Not Cancer Driver No 1 hippie 104 427 68 68 21
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie 86 94 13 13 1
LCP2 LCP2 Q13094 Lymphocyte cytosolic protein 2 chr5 Not Cancer Driver No 1 intact, hippie 107 390 80 80 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 Not Cancer Driver No 1 hippie 15 133 6 6 0
LGALS3BP LGALS3BP Q08380 Galectin-3-binding protein chr17 Not Cancer Driver No 1 hippie 62 9 0 0 0
LRP1 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 Not Cancer Driver No 1 hippie 664 317 52 52 1
LRRK1 LRRK1 Q38SD2 Leucine-rich repeat serine/threonine-protein kinase 1 chr15 Not Cancer Driver No 3 intact, hippie 289 261 33 33 0
LTK LTK P29376 Leukocyte tyrosine kinase receptor chr15 Not Cancer Driver No 2 intact, hippie 103 301 30 30 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie 95 84 12 12 0
MAP1LC3A_ENST00000397709 MAP1LC3A Q9H492 Microtubule-associated proteins 1A/1B light chain 3A chr20 Not Cancer Driver No 1 hippie 22 24 1 1 0
MAP4K1 MAP4K1 Q92918 Mitogen-activated protein kinase kinase kinase kinase 1 chr19 Not Cancer Driver No 1 hippie 116 276 41 41 0
MAP4K3 MAP4K3 Q8IVH8 Mitogen-activated protein kinase kinase kinase kinase 3 chr2 Not Cancer Driver No 1 hippie 116 313 45 45 0
MAP4K5 MAP4K5 Q9Y4K4 Mitogen-activated protein kinase kinase kinase kinase 5 chr14 Not Cancer Driver No 1 hippie 69 236 23 23 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 Not Cancer Driver No 1 hippie 39 25 1 1 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 2 intact, hippie 62 2 0 0 7
MAPK6 MAPK6 Q16659 Mitogen-activated protein kinase 6 chr15 Not Cancer Driver No 1 hippie 79 165 20 20 0
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 Not Cancer Driver No 1 hippie 64 94 9 9 0
MAPKAPK2 MAPKAPK2 P49137 MAP kinase-activated protein kinase 2 chr1 Not Cancer Driver No 1 hippie 43 92 5 5 0
MAT1A MAT1A Q00266 S-adenosylmethionine synthase isoform type-1 chr10 Not Cancer Driver No 1 hippie, biogrid 74 15 0 0 12
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 Census, Compendium Yes 2 intact, hippie, biogrid 226 62 15 15 19
MME_ENST00000492661 MME P08473 Neprilysin chr3 Not Cancer Driver No 1 hippie 189 40 17 17 4
MMP1 MMP1 P03956 Interstitial collagenase chr11 Not Cancer Driver No 1 hippie 83 113 18 18 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MPL MPL P40238 Thrombopoietin receptor chr1 Census Yes 1 hippie 77 129 19 19 14
MRPL44 MRPL44 Q9H9J2 39S ribosomal protein L44, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 37 45 2 2 1
MST1R MST1R Q04912 Macrophage-stimulating protein receptor chr3 Not Cancer Driver No 1 hippie 178 182 27 27 1
MTMR14 MTMR14 Q8NCE2 Myotubularin-related protein 14 chr3 Not Cancer Driver No 1 hippie 58 150 8 8 2
MTPN MTPN P58546 Myotrophin chr7 Not Cancer Driver No 1 hippie, biogrid 11 11 3 3 0
MTX2 MTX2 O75431 Metaxin-2 chr2 Not Cancer Driver No 1 hippie 33 0 0 0 0
MUC4 MUC4 Q99102 Mucin-4 chr3 Census Yes 1 hippie 1030 4368 876 876 0
MYH10_ENST00000269243 MYH10 P35580 Myosin-10 chr17 Not Cancer Driver No 1 hippie 258 1134 136 136 0
MYH11_ENST00000300036 MYH11 P35749 Myosin-11 chr16 Census, Compendium Yes 1 hippie 353 1180 201 201 2
MYH14_ENST00000596571 MYH14 Q7Z406 Myosin-14 chr19 Not Cancer Driver No 1 hippie 275 1215 169 169 5
MYH9 MYH9 P35579 Myosin-9 chr22 Census, Compendium Yes 2 intact, hippie 310 1120 160 160 17
MYO1C MYO1C O00159 Unconventional myosin-Ic chr17 Not Cancer Driver No 1 intact, hippie 110 66 11 11 0
MYO1D MYO1D O94832 Unconventional myosin-Id chr17 Not Cancer Driver No 1 intact, hippie 126 61 6 6 0
NCAPD2 NCAPD2 Q15021 Condensin complex subunit 1 chr12 Not Cancer Driver No 1 intact, hippie 124 345 35 35 0
NEDD8 NEDD8 Q15843 NEDD8 chr14 Not Cancer Driver No 1 hippie 10 36 5 5 0
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 Not Cancer Driver No 1 hippie 57 172 25 25 0
NPM1 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 hippie 29 249 22 22 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 intact, hippie 168 57 8 8 25
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 Not Cancer Driver No 1 hippie 155 117 18 18 1
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 Census, Compendium Yes 2 intact, hippie 249 57 21 21 0
NUDT21 NUDT21 O43809 Cleavage and polyadenylation specificity factor subunit 5 chr16 Not Cancer Driver No 1 intact, hippie 21 37 3 3 0
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
OSGEP OSGEP Q9NPF4 tRNA N6-adenosine threonylcarbamoyltransferase chr14 Not Cancer Driver No 1 hippie 46 32 4 4 14
OXT OXT P01178 Oxytocin-neurophysin 1 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 10 0 0 0 0
PAG1 PAG1 Q9NWQ8 Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 chr8 Not Cancer Driver No 1 hippie 58 394 54 54 0
PAICS_ENST00000512576 PAICS P22234 Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase chr4 Not Cancer Driver No 1 intact, hippie 23 35 3 3 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 Not Cancer Driver No 1 hippie 57 299 30 30 2
PDCD2L PDCD2L Q9BRP1 Programmed cell death protein 2-like chr19 Not Cancer Driver No 1 hippie, biogrid 35 83 6 6 0
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 Census, Compendium Yes 1 hippie 164 231 44 44 7
PEAK1_ENST00000312493 PEAK1 Q9H792 Inactive tyrosine-protein kinase PEAK1 chr15 Not Cancer Driver No 2 intact, hippie, biogrid 222 1232 150 150 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PIK3C2B PIK3C2B O00750 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta chr1 Not Cancer Driver No 1 hippie 241 425 71 71 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 5 intact, hippie 154 268 61 61 2
PIK3R2_ENST00000617130 PIK3R2 O00459 Phosphatidylinositol 3-kinase regulatory subunit beta chr19 Not Cancer Driver No 2 intact, hippie 96 418 47 47 3
PKD1L2_ENST00000337114 PKD1L2 Q7Z442-3 Isoform 3 of Polycystic kidney disease protein 1-like 2 chr16 Not Cancer Driver No 1 hippie 152 181 18 18 0
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 Census, Compendium Yes 1 hippie 158 186 21 21 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 Not Cancer Driver No 1 hippie 248 142 30 30 1
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLIN3 PLIN3 O60664 Perilipin-3 chr19 Not Cancer Driver No 1 hippie 44 256 34 34 0
PLPP3 PLPP3 O14495 Phospholipid phosphatase 3 chr1 Not Cancer Driver No 1 hippie 48 10 1 1 0
PLS3_ENST00000539310 PLS3 P13797 Plastin-3 chrX Not Cancer Driver No 1 hippie, biogrid 75 75 5 5 0
PLSCR1 PLSCR1 O15162 Phospholipid scramblase 1 chr3 Not Cancer Driver No 1 hippie 43 92 13 13 0
PPP1R8 PPP1R8 Q12972 Nuclear inhibitor of protein phosphatase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 24 251 19 19 0
PPP1R9B PPP1R9B Q96SB3 Neurabin-2 chr17 Not Cancer Driver No 1 hippie 47 695 35 35 0
PPP2R2A_ENST00000380737 PPP2R2A P63151 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform chr8 Not Cancer Driver No 1 intact, hippie 60 68 10 10 0
PPP2R2D PPP2R2D Q66LE6 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform chr10 Not Cancer Driver No 1 hippie 50 65 9 9 0
PPP2R5A PPP2R5A Q15172 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform chr1 Not Cancer Driver No 1 hippie 55 93 5 5 0
PRDX1_ENST00000319248 PRDX1 Q06830 Peroxiredoxin-1 chr1 Not Cancer Driver No 1 hippie 22 40 5 5 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 Not Cancer Driver No 1 hippie 72 124 17 17 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 Not Cancer Driver No 1 hippie 94 154 22 22 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 Compendium Yes 1 hippie 79 43 9 9 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 Not Cancer Driver No 1 hippie 538 421 61 61 2
PRKRA PRKRA O75569 Interferon-inducible double-stranded RNA-dependent protein kinase activator A chr2 Not Cancer Driver No 1 hippie 41 104 12 12 1
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 Not Cancer Driver No 1 hippie 83 72 6 6 0
PROCR PROCR Q9UNN8 Endothelial protein C receptor chr20 Not Cancer Driver No 1 hippie 42 5 1 1 0
PRSS3 PRSS3 P35030 Trypsin-3 chr9 Not Cancer Driver No 1 intact, hippie 50 30 0 0 0
PSPH_ENST00000275605 PSPH P78330 Phosphoserine phosphatase chr7 Not Cancer Driver No 2 intact, hippie, biogrid 44 21 6 6 3
PSTPIP2 PSTPIP2 Q9H939 Proline-serine-threonine phosphatase-interacting protein 2 chr18 Not Cancer Driver No 1 intact, hippie 50 89 22 22 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 Not Cancer Driver No 1 hippie 161 261 37 37 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 Not Cancer Driver No 1 hippie 134 425 55 55 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 Census, Compendium Yes 2 intact, hippie 129 260 38 38 60
PTPN12 PTPN12 Q05209 Tyrosine-protein phosphatase non-receptor type 12 chr7 Not Cancer Driver No 8 intact, hippie, biogrid 102 516 60 60 0
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 Not Cancer Driver No 1 hippie 57 120 14 14 0
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 Census, Compendium Yes 1 hippie 73 192 25 25 0
PTPRA_ENST00000399903 PTPRA P18433 Receptor-type tyrosine-protein phosphatase alpha chr20 Not Cancer Driver No 1 intact 98 210 21 21 0
PXN_ENST00000228307 PXN P49023 Paxillin chr12 Not Cancer Driver No 2 intact, hippie, biogrid 62 341 24 24 0
PYCR2 PYCR2 Q96C36 Pyrroline-5-carboxylate reductase 2 chr1 Not Cancer Driver No 1 intact, hippie 31 41 3 3 2
RAB3GAP2 RAB3GAP2 Q9H2M9 Rab3 GTPase-activating protein non-catalytic subunit chr1 Not Cancer Driver No 1 hippie 168 143 17 17 2
RAPGEF1_ENST00000372189 RAPGEF1 Q13905 Rap guanine nucleotide exchange factor 1 chr9 Not Cancer Driver No 1 hippie 158 589 87 87 0
RASA1 RASA1 P20936 Ras GTPase-activating protein 1 chr5 Compendium Yes 1 hippie 154 181 25 25 3
RASAL2_ENST00000462775 RASAL2 Q9UJF2 Ras GTPase-activating protein nGAP chr1 Not Cancer Driver No 2 intact, hippie, biogrid 164 606 86 86 0
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 Census, Compendium Yes 1 hippie 140 282 32 32 22
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 Census, Compendium Yes 2 intact, hippie 208 105 12 12 139
RFFL_ENST00000394597 RFFL Q8WZ73 E3 ubiquitin-protein ligase rififylin chr17 Not Cancer Driver No 3 intact, hippie, biogrid 50 150 21 21 0
RIN3 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 intact, hippie 137 417 61 61 0
RMDN1 RMDN1 Q96DB5 Regulator of microtubule dynamics protein 1 chr8 Not Cancer Driver No 1 hippie, biogrid 25 17 0 0 0
RPL22 RPL22 P35268 60S ribosomal protein L22 chr1 Census, Compendium Yes 1 hippie 26 15 1 1 0
RPS19_ENST00000600467 RPS19 P39019 40S ribosomal protein S19 chr19 Not Cancer Driver No 1 hippie 15 61 3 3 23
RUVBL1 RUVBL1 Q9Y265 RuvB-like 1 chr3 Not Cancer Driver No 1 hippie 54 67 7 7 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 Not Cancer Driver No 1 hippie 62 100 13 13 0
S100A6_ENST00000496817 S100A6 P06703 Protein S100-A6 chr1 Not Cancer Driver No 1 intact, hippie 5 4 0 0 0
S100A7_ENST00000368722 S100A7 P31151 Protein S100-A7 chr1 Census Yes 1 hippie 39 28 14 14 0
S100A8 S100A8 P05109 Protein S100-A8 chr1 Not Cancer Driver No 2 intact, hippie 22 8 4 4 0
S100A9 S100A9 P06702 Protein S100-A9 chr1 Not Cancer Driver No 1 hippie 18 76 7 7 0
SCLT1 SCLT1 Q96NL6 Sodium channel and clathrin linker 1 chr4 Not Cancer Driver No 1 intact, hippie 98 398 61 61 0
SEC16A SEC16A O15027 Protein transport protein Sec16A chr9 Not Cancer Driver No 1 hippie 285 1923 235 235 0
SFN SFN P31947 14-3-3 protein sigma chr1 Not Cancer Driver No 1 hippie 27 75 9 9 0
SH2B2 SH2B2 O14492-2 Isoform 2 of SH2B adapter protein 2 chr7 Not Cancer Driver No 1 hippie 46 388 19 19 0
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 Not Cancer Driver No 2 intact, hippie 84 397 58 58 0
SHC2 SHC2 P98077 SHC-transforming protein 2 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 66 362 44 44 0
SHCBP1 SHCBP1 Q8NEM2 SHC SH2 domain-binding protein 1 chr16 Not Cancer Driver No 1 hippie 67 73 8 8 0
SIRPA_ENST00000400068 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 Census, Compendium Yes 1 hippie 96 281 51 51 0
SIRT4 SIRT4 Q9Y6E7 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial chr12 Not Cancer Driver No 1 hippie 46 4 0 0 0
SLC25A11 SLC25A11 Q02978 Mitochondrial 2-oxoglutarate/malate carrier protein chr17 Not Cancer Driver No 1 intact, hippie 37 16 1 1 3
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 Census, Compendium Yes 1 intact, hippie 198 195 17 17 8
SOS1_ENST00000402219 SOS1 Q07889 Son of sevenless homolog 1 chr2 Compendium Yes 3 intact, hippie 197 458 62 62 38
SOS2 SOS2 Q07890 Son of sevenless homolog 2 chr14 Not Cancer Driver No 1 hippie 173 362 54 54 2
SP1 SP1 P08047 Transcription factor Sp1 chr12 Not Cancer Driver No 1 hippie 96 599 71 71 0
SPOCK1 SPOCK1 Q08629 Testican-1 chr5 Not Cancer Driver No 1 hippie 82 107 16 16 0
SPTA1_ENST00000368147 SPTA1 P02549 Spectrin alpha chain, erythrocytic 1 chr1 Not Cancer Driver No 1 intact, hippie 1046 707 294 294 21
SPTAN1_ENST00000372731 SPTAN1 Q13813 Spectrin alpha chain, non-erythrocytic 1 chr9 Not Cancer Driver No 1 hippie 315 980 114 114 0
SPTBN1 SPTBN1 Q01082 Spectrin beta chain, non-erythrocytic 1 chr2 Not Cancer Driver No 1 hippie 311 869 123 123 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 2 intact, hippie 53 130 11 11 1
SSBP1_ENST00000484178 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 27 0 0 0 6
STAT5A_ENST00000590949 STAT5A P42229 Signal transducer and activator of transcription 5A chr17 Not Cancer Driver No 2 intact, hippie 89 125 14 14 0
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 Census, Compendium Yes 1 hippie 93 144 19 19 5
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 97 111 23 23 18
SUV39H2 SUV39H2 Q9H5I1 Histone-lysine N-methyltransferase SUV39H2 chr10 Not Cancer Driver No 1 hippie 39 23 1 1 0
SVIL SVIL O95425 Supervillin chr10 Not Cancer Driver No 1 hippie 308 1423 192 192 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 Census Yes 2 intact, hippie 96 131 27 27 5
TBRG4_ENST00000494076 TBRG4 Q969Z0 FAST kinase domain-containing protein 4 chr7 Not Cancer Driver No 1 hippie, biogrid 74 60 2 2 0
TEC TEC P42680 Tyrosine-protein kinase Tec chr4 Census, Compendium Yes 1 hippie 91 57 15 15 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 Not Cancer Driver No 1 intact, hippie 219 126 22 22 10
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 Census, Compendium Yes 1 intact, hippie 106 60 16 16 25
TIMM50_ENST00000607714 TIMM50 Q3ZCQ8 Mitochondrial import inner membrane translocase subunit TIM50 chr19 Not Cancer Driver No 1 hippie 39 75 7 7 0
TLK1 TLK1 Q9UKI8 Serine/threonine-protein kinase tousled-like 1 chr2 Not Cancer Driver No 1 hippie 103 388 53 53 0
TMED1 TMED1 Q13445 Transmembrane emp24 domain-containing protein 1 chr19 Not Cancer Driver No 1 intact, hippie 26 26 3 3 0
TPR TPR P12270 Nucleoprotein TPR chr1 Census Yes 1 hippie 311 1990 266 266 0
TRIM15 TRIM15 Q9C019 Tripartite motif-containing protein 15 chr6 Not Cancer Driver No 1 hippie 69 79 11 11 0
TUBA1A TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 hippie 59 52 11 11 8
TUBA1B TUBA1B P68363 Tubulin alpha-1B chain chr12 Not Cancer Driver No 1 hippie 41 52 9 9 0
TUBA1C_ENST00000301072 TUBA1C Q9BQE3 Tubulin alpha-1C chain chr12 Not Cancer Driver No 1 hippie 39 50 5 5 0
TUBA4B TUBA4B Q9H853 Putative tubulin-like protein alpha-4B chr2 Not Cancer Driver No 1 hippie 43 27 3 3 0
TUBA8 TUBA8 Q9NY65 Tubulin alpha-8 chain chr22 Not Cancer Driver No 1 hippie 50 32 0 0 0
TUBAL3 TUBAL3 A6NHL2 Tubulin alpha chain-like 3 chr10 Not Cancer Driver No 1 hippie 85 25 3 3 0
TUBB TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 hippie 40 63 11 11 5
TUBB2B TUBB2B Q9BVA1 Tubulin beta-2B chain chr6 Not Cancer Driver No 1 hippie 43 68 10 10 10
TUBB3 TUBB3 Q13509 Tubulin beta-3 chain chr16 Not Cancer Driver No 1 hippie 67 53 10 10 12
TUBB4B TUBB4B P68371 Tubulin beta-4B chain chr9 Not Cancer Driver No 1 hippie 52 65 11 11 2
TUBB6 TUBB6 Q9BUF5 Tubulin beta-6 chain chr18 Not Cancer Driver No 1 hippie 69 51 5 5 1
UBASH3B UBASH3B Q8TF42 Ubiquitin-associated and SH3 domain-containing protein B chr11 Not Cancer Driver No 2 intact, hippie 86 73 6 6 0
USP11 USP11 P51784 Ubiquitin carboxyl-terminal hydrolase 11 chrX Not Cancer Driver No 1 intact, hippie 140 210 28 28 0
USP15 USP15 Q9Y4E8 Ubiquitin carboxyl-terminal hydrolase 15 chr12 Not Cancer Driver No 1 hippie 136 259 39 39 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 Not Cancer Driver No 1 intact, hippie 170 215 45 45 0
USP9X_ENST00000378308 USP9X Q93008 Probable ubiquitin carboxyl-terminal hydrolase FAF-X chrX Census, Compendium Yes 2 intact, hippie 339 405 51 51 1
USP9Y USP9Y O00507 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y chrY Not Cancer Driver No 1 intact, hippie 83 349 6 6 0
VAV1 VAV1 P15498 Proto-oncogene vav chr19 Census, Compendium Yes 1 hippie 165 113 19 19 0
VAV3 VAV3 Q9UKW4 Guanine nucleotide exchange factor VAV3 chr1 Not Cancer Driver No 1 hippie 153 102 18 18 0
VPS33A VPS33A Q96AX1 Vacuolar protein sorting-associated protein 33A chr12 Not Cancer Driver No 1 hippie 73 46 8 8 1
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 Not Cancer Driver No 1 hippie 65 62 10 10 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 2 intact, hippie 32 41 3 3 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 1 intact, hippie 26 77 9 9 2
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 2 intact, hippie 30 81 10 10 0
ZAP70 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 Not Cancer Driver No 2 intact, hippie 126 117 17 17 8
ZBTB7A_ENST00000601588 ZBTB7A O95365 Zinc finger and BTB domain-containing protein 7A chr19 Not Cancer Driver No 1 hippie 60 285 30 30 0