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SH2D2A_ENST00000368199 ,SH2D2A ,Q9NP31
  • Uniprot Accession= Q9NP31
  • Ensembl Transcript= ENST00000368199.7
  • Uniprot Name= SH2D2A
  • Name= SH2 domain-containing protein 2A
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 2
  • Number of Interaction partner in biogrid: 11
  • Number of Interaction partner in hippie: 51
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
APPL1 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 Not Cancer Driver No 1 hippie 67 292 31 31 1
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie, biogrid 196 443 88 88 169
ARID5A ARID5A Q03989 AT-rich interactive domain-containing protein 5A chr2 Not Cancer Driver No 1 hippie 64 373 42 42 0
ASB3 ASB3 Q9Y575 Ankyrin repeat and SOCS box protein 3 chr2 Not Cancer Driver No 1 hippie 71 0 0 0 0
CLCN2 CLCN2 P51788 Chloride channel protein 2 chr3 Not Cancer Driver No 1 hippie, biogrid 124 224 38 38 8
CRK CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 1 hippie 30 197 23 23 0
DAPK1_ENST00000622514 DAPK1 P53355 Death-associated protein kinase 1 chr9 Not Cancer Driver No 1 hippie 193 114 11 11 0
DCAF12L1 DCAF12L1 Q5VU92 DDB1- and CUL4-associated factor 12-like protein 1 chrX Not Cancer Driver No 1 hippie 193 51 16 16 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 2 hippie, biogrid 444 223 35 35 1
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 2 hippie, biogrid 275 314 41 41 1
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 Census, Compendium Yes 1 hippie, biogrid 298 396 70 70 3
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 Census, Compendium Yes 1 hippie, biogrid 428 323 116 116 2
GAB1_ENST00000262994 GAB1 Q13480 GRB2-associated-binding protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 79 570 68 68 1
HAVCR2 HAVCR2 Q8TDQ0 Hepatitis A virus cellular receptor 2 chr5 Not Cancer Driver No 1 hippie 69 17 2 2 3
ITK ITK Q08881 Tyrosine-protein kinase ITK/TSK chr5 Census Yes 1 hippie 139 43 10 10 1
KDM1B_ENST00000449850 KDM1B Q8NB78 Lysine-specific histone demethylase 1B chr6 Not Cancer Driver No 3 intact, hippie, biogrid 81 74 11 11 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 Census, Compendium Yes 1 hippie 357 275 55 55 2
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 Census, Compendium Yes 1 hippie, biogrid 226 83 33 33 21
LASP1 LASP1 Q14847 LIM and SH3 domain protein 1 chr17 Census Yes 1 hippie 29 198 24 24 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie 86 94 13 13 1
LNX1 LNX1 Q8TBB1 E3 ubiquitin-protein ligase LNX chr4 Not Cancer Driver No 1 hippie 117 261 40 40 0
LRRFIP1 LRRFIP1 Q32MZ4 Leucine-rich repeat flightless-interacting protein 1 chr2 Not Cancer Driver No 1 hippie 88 785 88 88 0
LRRK1 LRRK1 Q38SD2 Leucine-rich repeat serine/threonine-protein kinase 1 chr15 Not Cancer Driver No 1 hippie 289 261 33 33 0
MAP3K2_ENST00000344908 MAP3K2 Q9Y2U5 Mitogen-activated protein kinase kinase kinase 2 chr2 Not Cancer Driver No 1 hippie 75 313 47 47 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 Not Cancer Driver No 1 hippie 92 490 50 50 0
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 Census, Compendium Yes 1 hippie, biogrid 226 62 15 15 19
MFHAS1 MFHAS1 Q9Y4C4 Malignant fibrous histiocytoma-amplified sequence 1 chr8 Not Cancer Driver No 1 hippie 95 98 9 9 0
NAA16 NAA16 Q6N069 N-alpha-acetyltransferase 16, NatA auxiliary subunit chr13 Not Cancer Driver No 1 hippie 91 74 12 12 0
PEAK1_ENST00000312493 PEAK1 Q9H792 Inactive tyrosine-protein kinase PEAK1 chr15 Not Cancer Driver No 2 intact, hippie, biogrid 222 1232 150 150 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 1 hippie 154 268 61 61 2
PIK3R3_ENST00000372006 PIK3R3 Q92569 Phosphatidylinositol 3-kinase regulatory subunit gamma chr1 Not Cancer Driver No 1 hippie 51 149 20 20 0
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 Census, Compendium Yes 1 hippie 158 186 21 21 0
PLEKHB1 PLEKHB1 Q9UF11 Pleckstrin homology domain-containing family B member 1 chr11 Not Cancer Driver No 1 hippie 25 47 4 4 0
PPP1R21 PPP1R21 Q6ZMI0 Protein phosphatase 1 regulatory subunit 21 chr2 Not Cancer Driver No 1 hippie 86 315 33 33 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 Not Cancer Driver No 1 hippie 134 425 55 55 0
RAD54B RAD54B Q9Y620 DNA repair and recombination protein RAD54B chr8 Not Cancer Driver No 1 hippie 112 120 16 16 0
RNF123 RNF123 Q5XPI4 E3 ubiquitin-protein ligase RNF123 chr3 Not Cancer Driver No 1 hippie 167 220 28 28 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 Census, Compendium Yes 1 hippie 79 137 12 12 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 Census, Compendium Yes 1 hippie 97 111 19 19 5
SOCS3 SOCS3 O14543 Suppressor of cytokine signaling 3 chr17 Not Cancer Driver No 1 hippie 27 111 14 14 0
SPTB_ENST00000389721 SPTB P11277 Spectrin beta chain, erythrocytic chr14 Not Cancer Driver No 1 hippie 328 562 70 70 7
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie 53 130 11 11 1
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 Census, Compendium Yes 1 hippie 110 152 15 15 19
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 Census Yes 1 hippie 96 131 27 27 5
TENT5A TENT5A Q96IP4 Terminal nucleotidyltransferase 5A chr6 Not Cancer Driver No 1 hippie 43 0 0 0 0
TENT5B TENT5B Q96A09 Terminal nucleotidyltransferase 5B chr1 Not Cancer Driver No 1 hippie 52 57 6 6 0
TSC1 TSC1 Q92574 Hamartin chr9 Census, Compendium Yes 1 hippie 135 732 78 78 11
TXK TXK P42681 Tyrosine-protein kinase TXK chr4 Not Cancer Driver No 1 hippie 87 61 9 9 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 88 186 16 16 16
ZHX3_ENST00000559234 ZHX3 Q9H4I2 Zinc fingers and homeoboxes protein 3 chr20 Not Cancer Driver No 1 hippie 111 617 73 73 0
ZSCAN1 ZSCAN1 Q8NBB4 Zinc finger and SCAN domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 132 298 98 98 0