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SH2D1B ,SH2D1B ,O14796
  • Uniprot Accession= O14796
  • Ensembl Transcript= ENST00000367929.2
  • Uniprot Name= SH2D1B
  • Name= SH2 domain-containing protein 1B
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 19
  • Number of Interaction partner in biogrid: 12
  • Number of Interaction partner in hippie: 46
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABLIM1 ABLIM1 O14639 Actin-binding LIM protein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 123 379 63 63 0
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 23 20 2 2 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie, biogrid 196 443 88 88 169
BLK BLK P51451 Tyrosine-protein kinase Blk chr8 Not Cancer Driver No 1 intact, hippie 94 75 21 21 0
CD244 CD244 Q9BZW8 Natural killer cell receptor 2B4 chr1 Not Cancer Driver No 1 hippie 77 92 22 22 0
CD84 CD84 Q9UIB8 SLAM family member 5 chr1 Not Cancer Driver No 3 intact, hippie 82 52 11 11 0
DAPP1 DAPP1 Q9UN19 Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide chr4 Not Cancer Driver No 1 intact, hippie 50 40 9 9 0
DDIT4L DDIT4L Q96D03 DNA damage-inducible transcript 4-like protein chr4 Not Cancer Driver No 1 hippie 48 5 3 3 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie, biogrid 444 223 35 35 1
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 2 hippie, biogrid 275 314 41 41 1
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 Census, Compendium Yes 1 hippie, biogrid 298 396 70 70 3
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 Census, Compendium Yes 1 hippie, biogrid 428 323 116 116 2
FOS FOS P01100 Protein c-Fos chr14 Not Cancer Driver No 1 hippie 45 245 33 33 0
GAB1_ENST00000262994 GAB1 Q13480 GRB2-associated-binding protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 79 570 68 68 1
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie 24 200 13 13 0
INPP5D INPP5D Q92835 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 chr2 Not Cancer Driver No 1 intact, hippie 176 578 90 90 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 Census, Compendium Yes 1 hippie, biogrid 226 83 33 33 21
LY9 LY9 Q9HBG7 T-lymphocyte surface antigen Ly-9 chr1 Not Cancer Driver No 1 hippie 141 249 49 49 0
MAGEB4 MAGEB4 O15481 Melanoma-associated antigen B4 chrX Not Cancer Driver No 1 hippie 100 186 54 54 0
MAPK8IP2 MAPK8IP2 Q13387 C-Jun-amino-terminal kinase-interacting protein 2 chr22 Not Cancer Driver No 1 hippie 49 568 27 27 0
MEOX2 MEOX2 P50222 Homeobox protein MOX-2 chr7 Not Cancer Driver No 1 intact, hippie 70 274 63 63 0
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 Census, Compendium Yes 1 intact, hippie, biogrid 226 62 15 15 19
NFKBID NFKBID Q8NI38 NF-kappa-B inhibitor delta chr19 Not Cancer Driver No 1 intact, hippie 47 124 20 20 0
NUTM1_ENST00000614490 NUTM1 Q86Y26 NUT family member 1 chr15 Census Yes 1 hippie 202 967 175 175 0
OLIG1 OLIG1 Q8TAK6 Oligodendrocyte transcription factor 1 chr21 Not Cancer Driver No 1 intact, hippie 6 130 1 1 0
PECAM1 PECAM1 P16284 Platelet endothelial cell adhesion molecule chr17 Not Cancer Driver No 1 hippie 2 153 2 2 0
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 Census, Compendium Yes 1 hippie 158 186 21 21 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 Not Cancer Driver No 1 hippie 248 142 30 30 1
PRDX1_ENST00000319248 PRDX1 Q06830 Peroxiredoxin-1 chr1 Not Cancer Driver No 1 intact, hippie 22 40 5 5 0
PRMT3 PRMT3 O60678 Protein arginine N-methyltransferase 3 chr11 Not Cancer Driver No 1 hippie, biogrid 68 52 9 9 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 Not Cancer Driver No 1 intact, hippie 134 425 55 55 0
PTPN18 PTPN18 Q99952 Tyrosine-protein phosphatase non-receptor type 18 chr2 Not Cancer Driver No 1 hippie 51 138 8 8 0
ROBO1 ROBO1 Q9Y6N7 Roundabout homolog 1 chr3 Not Cancer Driver No 1 hippie, biogrid 353 1122 234 234 0
SH2D1A SH2D1A O60880 SH2 domain-containing protein 1A chrX Not Cancer Driver No 1 intact, hippie 40 24 8 8 19
SIRPA_ENST00000400068 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 Census, Compendium Yes 1 hippie, biogrid 96 281 51 51 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 Not Cancer Driver No 2 intact, hippie 82 64 10 10 0
SLAMF6 SLAMF6 Q96DU3 SLAM family member 6 chr1 Not Cancer Driver No 1 hippie 69 60 14 14 0
SLAMF7 SLAMF7 Q9NQ25 SLAM family member 7 chr1 Not Cancer Driver No 1 intact, hippie 66 53 14 14 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie 53 130 11 11 1
STAT4_ENST00000358470 STAT4 Q14765 Signal transducer and activator of transcription 4 chr2 Not Cancer Driver No 1 intact, hippie 154 143 36 36 0
TCF12_ENST00000267811 TCF12 Q99081 Transcription factor 12 chr15 Census Yes 1 intact, hippie 105 680 105 105 3
TGFB1I1 TGFB1I1 O43294 Transforming growth factor beta-1-induced transcript 1 protein chr16 Not Cancer Driver No 1 intact, hippie 61 219 34 34 0
TNK2_ENST00000333602 TNK2 Q07912 Activated CDC42 kinase 1 chr3 Not Cancer Driver No 1 intact, hippie 137 593 81 81 0
TRIM54_ENST00000380075 TRIM54 Q9BYV2 Tripartite motif-containing protein 54 chr2 Not Cancer Driver No 1 intact, hippie 63 98 17 17 0
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 Not Cancer Driver No 1 intact, hippie 105 203 10 10 39