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SGCA ,SGCA ,Q16586
  • Uniprot Accession= Q16586
  • Ensembl Transcript= ENST00000262018.7
  • Uniprot Name= SGCA
  • Name= Alpha-sarcoglycan
  • Chromosome= chr17
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 93
  • Number of Interaction partner in hippie: 106
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCB6 ABCB6 Q9NP58 ATP-binding cassette sub-family B member 6 chr2 Not Cancer Driver No 1 hippie, biogrid 87 27 1 1 11
ACP2 ACP2 P11117 Lysosomal acid phosphatase chr11 Not Cancer Driver No 2 hippie, biogrid 41 77 11 11 0
ACSL1_ENST00000281455 ACSL1 P33121 Long-chain-fatty-acid--CoA ligase 1 chr4 Not Cancer Driver No 1 hippie, biogrid 85 27 1 1 0
ACVR1B_ENST00000257963 ACVR1B P36896 Activin receptor type-1B chr12 Census Yes 1 hippie, biogrid 114 0 0 0 0
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 Not Cancer Driver No 1 hippie, biogrid 86 129 13 13 0
ADGRE5 ADGRE5 P48960 Adhesion G protein-coupled receptor E5 chr19 Not Cancer Driver No 1 hippie 115 109 10 10 0
AGPAT2_ENST00000538402 AGPAT2 O15120 1-acyl-sn-glycerol-3-phosphate acyltransferase beta chr9 Not Cancer Driver No 1 hippie, biogrid 25 23 2 2 3
AHCTF1 AHCTF1 Q8WYP5 Protein ELYS chr1 Not Cancer Driver No 1 hippie, biogrid 296 1060 130 130 0
ALG11 ALG11 Q2TAA5 GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase chr13 Not Cancer Driver No 1 hippie, biogrid 46 0 0 0 5
APLP2 APLP2 Q06481 Amyloid beta precursor like protein 2 chr11 Not Cancer Driver No 1 hippie, biogrid 96 393 48 48 0
ARFGEF1 ARFGEF1 Q9Y6D6 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 chr8 Not Cancer Driver No 1 hippie, biogrid 243 456 54 54 0
ARFGEF2 ARFGEF2 Q9Y6D5 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 chr20 Not Cancer Driver No 1 hippie, biogrid 254 358 63 63 0
ATP1A3_ENST00000302102 ATP1A3 P13637 Sodium/potassium-transporting ATPase subunit alpha-3 chr19 Not Cancer Driver No 1 hippie, biogrid 200 115 29 29 31
ATP2C1_ENST00000508532 ATP2C1 P98194 Calcium-transporting ATPase type 2C member 1 chr3 Not Cancer Driver No 1 hippie, biogrid 125 44 5 5 20
B3GAT3 B3GAT3 O94766 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 chr11 Not Cancer Driver No 1 hippie, biogrid 42 139 17 17 2
BGN BGN P21810 Biglycan chrX Not Cancer Driver No 1 hippie 63 26 3 3 2
BSCL2_ENST00000421906 BSCL2 Q96G97 Seipin chr11 Not Cancer Driver No 1 hippie, biogrid 55 125 15 15 5
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie, biogrid 150 400 82 82 5
CDS2 CDS2 O95674 Phosphatidate cytidylyltransferase 2 chr20 Not Cancer Driver No 1 hippie, biogrid 48 49 4 4 0
CMTM6 CMTM6 Q9NX76 CKLF-like MARVEL transmembrane domain-containing protein 6 chr3 Not Cancer Driver No 1 hippie, biogrid 10 30 0 0 0
CTPS2_ENST00000380241 CTPS2 Q9NRF8 CTP synthase 2 chrX Not Cancer Driver No 1 hippie, biogrid 57 65 9 9 0
DAD1 DAD1 P61803 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 chr14 Not Cancer Driver No 3 hippie, biogrid 7 0 0 0 0
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 Not Cancer Driver No 2 hippie, biogrid 102 485 61 61 4
DAGLB DAGLB Q8NCG7 Diacylglycerol lipase-beta chr7 Not Cancer Driver No 1 hippie, biogrid 69 37 3 3 0
DDR1_ENST00000324771 DDR1 Q08345 Epithelial discoidin domain-containing receptor 1 chr6 Not Cancer Driver No 1 hippie, biogrid 123 253 49 49 0
DNAJC11 DNAJC11 Q9NVH1 DnaJ homolog subfamily C member 11 chr1 Not Cancer Driver No 1 hippie, biogrid 66 123 14 14 0
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 Census Yes 1 hippie, biogrid 138 270 43 43 22
DOCK5 DOCK5 Q9H7D0 Dedicator of cytokinesis protein 5 chr8 Not Cancer Driver No 1 hippie, biogrid 278 330 45 45 0
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 Not Cancer Driver No 1 hippie, biogrid 147 211 38 38 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 Not Cancer Driver No 1 hippie, biogrid 55 7 2 2 0
FAM171A2 FAM171A2 A8MVW0 Protein FAM171A2 chr17 Not Cancer Driver No 1 hippie, biogrid 13 478 4 4 0
FASTKD5 FASTKD5 Q7L8L6 FAST kinase domain-containing protein 5, mitochondrial chr20 Not Cancer Driver No 1 hippie, biogrid 86 94 8 8 0
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 hippie 394 1243 185 185 8
FSTL1 FSTL1 Q12841 Follistatin-related protein 1 chr3 Not Cancer Driver No 3 hippie, biogrid 41 51 7 7 0
GGCX GGCX P38435 Vitamin K-dependent gamma-carboxylase chr2 Not Cancer Driver No 1 hippie, biogrid 77 131 15 15 8
GLT8D1_ENST00000478968 GLT8D1 Q68CQ7 Glycosyltransferase 8 domain-containing protein 1 chr3 Not Cancer Driver No 1 hippie, biogrid 37 10 1 1 0
GPR107_ENST00000610997 GPR107 Q5VW38 Protein GPR107 chr9 Not Cancer Driver No 1 hippie, biogrid 54 69 5 5 0
GPR180 GPR180 Q86V85 Integral membrane protein GPR180 chr13 Not Cancer Driver No 3 hippie, biogrid 38 11 1 1 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 hippie 28 10 1 1 0
HEATR1 HEATR1 Q9H583 HEAT repeat-containing protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 291 43 5 5 0
HIP1R HIP1R O75146 Huntingtin-interacting protein 1-related protein chr12 Not Cancer Driver No 1 hippie, biogrid 94 524 34 34 0
HLA-F_ENST00000376861 HLA-F P30511 HLA class I histocompatibility antigen, alpha chain F chr6 Not Cancer Driver No 1 hippie, biogrid 43 115 22 22 0
HSPA13 HSPA13 P48723 Heat shock 70 kDa protein 13 chr21 Not Cancer Driver No 1 hippie, biogrid 74 48 7 7 0
INTS4 INTS4 Q96HW7 Integrator complex subunit 4 chr11 Not Cancer Driver No 1 hippie, biogrid 117 82 7 7 0
INTS5 INTS5 Q6P9B9 Integrator complex subunit 5 chr11 Not Cancer Driver No 1 hippie, biogrid 123 189 22 22 0
ITFG1 ITFG1 Q8TB96 T-cell immunomodulatory protein chr16 Not Cancer Driver No 1 hippie, biogrid 70 18 3 3 0
ITGB1BP2 ITGB1BP2 Q9UKP3 Integrin beta-1-binding protein 2 chrX Not Cancer Driver No 1 hippie 51 137 22 22 0
ITM2B ITM2B Q9Y287 Integral membrane protein 2B chr13 Not Cancer Driver No 1 hippie, biogrid 21 12 0 0 1
KCNN4 KCNN4 O15554 Intermediate conductance calcium-activated potassium channel protein 4 chr19 Not Cancer Driver No 1 hippie, biogrid 60 31 6 6 3
LEMD2_ENST00000614475 LEMD2 Q8NC56 LEM domain-containing protein 2 chr6 Not Cancer Driver No 1 hippie, biogrid 44 211 4 4 2
LEMD3 LEMD3 Q9Y2U8 Inner nuclear membrane protein Man1 chr12 Not Cancer Driver No 3 hippie, biogrid 78 509 33 33 0
LGR4 LGR4 Q9BXB1 Leucine-rich repeat-containing G-protein coupled receptor 4 chr11 Not Cancer Driver No 1 hippie, biogrid 108 16 3 3 0
LPAR2_ENST00000586703 LPAR2 Q9HBW0 Lysophosphatidic acid receptor 2 chr19 Not Cancer Driver No 1 hippie, biogrid 47 2 0 0 0
LRFN1 LRFN1 Q9P244 Leucine-rich repeat and fibronectin type III domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 96 278 37 37 0
MAGT1_ENST00000618282 MAGT1 Q9H0U3 Magnesium transporter protein 1 chrX Not Cancer Driver No 1 hippie, biogrid 63 0 0 0 1
MBOAT7 MBOAT7 Q96N66 Lysophospholipid acyltransferase 7 chr19 Not Cancer Driver No 1 hippie, biogrid 69 25 3 3 0
MED23 MED23 Q9ULK4 Mediator of RNA polymerase II transcription subunit 23 chr6 Not Cancer Driver No 1 hippie, biogrid 158 28 2 2 1
MGST3 MGST3 O14880 Microsomal glutathione S-transferase 3 chr1 Not Cancer Driver No 1 hippie, biogrid 17 0 0 0 0
MICA_ENST00000616296 MICA A0A024RCL3 MHC class I polypeptide-related sequence A chr6 Not Cancer Driver No 1 biogrid 37 49 8 8 0
MROH1 MROH1 Q8NDA8 Maestro heat-like repeat-containing protein family member 1 chr8 Not Cancer Driver No 1 hippie, biogrid 52 67 0 0 0
MSMO1 MSMO1 Q15800 Methylsterol monooxygenase 1 chr4 Not Cancer Driver No 1 hippie, biogrid 42 4 0 0 2
MYADM MYADM Q96S97 Myeloid-associated differentiation marker chr19 Not Cancer Driver No 1 hippie, biogrid 73 0 0 0 0
NIN NIN Q8N4C6 Ninein chr14 Census, Compendium Yes 1 hippie, biogrid 239 1392 164 164 2
NMU NMU P48645 Neuromedin-U chr4 Not Cancer Driver No 1 hippie, biogrid 22 31 2 2 0
PCDH1_ENST00000394536 PCDH1 Q08174 Protocadherin-1 chr5 Not Cancer Driver No 1 hippie, biogrid 140 676 90 90 0
PEX3 PEX3 P56589 Peroxisomal biogenesis factor 3 chr6 Not Cancer Driver No 1 hippie, biogrid 31 24 0 0 2
PIGT PIGT Q969N2 GPI transamidase component PIG-T chr20 Not Cancer Driver No 1 hippie, biogrid 51 36 6 6 1
PRSS8 PRSS8 Q16651 Prostasin chr16 Not Cancer Driver No 1 hippie, biogrid 30 27 3 3 0
PTPRF PTPRF P10586 Receptor-type tyrosine-protein phosphatase F chr1 Not Cancer Driver No 1 hippie, biogrid 268 696 96 96 0
PTPRS PTPRS Q13332 Receptor-type tyrosine-protein phosphatase S chr19 Not Cancer Driver No 1 hippie, biogrid 250 829 111 111 0
PTPRU PTPRU Q92729 Receptor-type tyrosine-protein phosphatase U chr1 Not Cancer Driver No 3 hippie, biogrid 248 325 64 64 0
RAD23A RAD23A P54725 UV excision repair protein RAD23 homolog A chr19 Not Cancer Driver No 1 hippie 50 283 41 41 0
RNF149 RNF149 Q8NC42 E3 ubiquitin-protein ligase RNF149 chr2 Not Cancer Driver No 1 hippie, biogrid 41 102 10 10 0
RNF213 RNF213 Q63HN8 E3 ubiquitin-protein ligase RNF213 chr17 Census, Compendium Yes 1 hippie, biogrid 560 623 75 75 3
RPN2 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 hippie, biogrid 53 26 4 4 0
RTN2 RTN2 O75298 Reticulon-2 chr19 Not Cancer Driver No 1 hippie, biogrid 85 270 55 55 1
SCAMP3 SCAMP3 O14828 Secretory carrier-associated membrane protein 3 chr1 Not Cancer Driver No 1 hippie, biogrid 46 130 23 23 0
SERPINH1_ENST00000358171 SERPINH1 P50454 Serpin H1 chr11 Not Cancer Driver No 1 hippie 51 52 6 6 1
SFXN2 SFXN2 Q96NB2 Sideroflexin-2 chr10 Not Cancer Driver No 1 hippie, biogrid 44 0 0 0 0
SGCB SGCB Q16585 Beta-sarcoglycan chr4 Not Cancer Driver No 1 hippie 36 80 8 8 12
SGCD_ENST00000435422 SGCD Q92629 Delta-sarcoglycan chr5 Not Cancer Driver No 1 hippie 67 74 20 20 2
SGTA SGTA O43765 Small glutamine-rich tetratricopeptide repeat-containing protein alpha chr19 Not Cancer Driver No 1 hippie 38 159 23 23 0
SGTB SGTB Q96EQ0 Small glutamine-rich tetratricopeptide repeat-containing protein beta chr5 Not Cancer Driver No 1 hippie 28 114 10 10 0
SLC25A17 SLC25A17 O43808 Peroxisomal membrane protein PMP34 chr22 Not Cancer Driver No 1 hippie, biogrid 32 0 0 0 0
SLC25A19_ENST00000416858 SLC25A19 Q9HC21 Mitochondrial thiamine pyrophosphate carrier chr17 Not Cancer Driver No 1 hippie, biogrid 34 16 0 0 2
SLC25A33 SLC25A33 Q9BSK2 Solute carrier family 25 member 33 chr1 Not Cancer Driver No 1 hippie, biogrid 23 4 0 0 0
SLC25A4 SLC25A4 P12235 ADP/ATP translocase 1 chr4 Not Cancer Driver No 1 hippie, biogrid 24 0 0 0 9
SLC35E1 SLC35E1 Q96K37 Solute carrier family 35 member E1 chr19 Not Cancer Driver No 1 hippie, biogrid 26 50 6 6 0
SLC38A10 SLC38A10 Q9HBR0 Putative sodium-coupled neutral amino acid transporter 10 chr17 Not Cancer Driver No 1 hippie, biogrid 128 719 82 82 0
SLC7A11 SLC7A11 Q9UPY5 Cystine/glutamate transporter chr4 Not Cancer Driver No 1 hippie, biogrid 70 15 2 2 0
SMPD4 SMPD4 Q9NXE4 Sphingomyelin phosphodiesterase 4 chr2 Not Cancer Driver No 1 hippie, biogrid 114 80 12 12 1
SORT1 SORT1 Q99523 Sortilin chr1 Not Cancer Driver No 1 hippie, biogrid 69 110 2 2 0
STARD3 STARD3 Q14849 StAR-related lipid transfer protein 3 chr17 Not Cancer Driver No 1 hippie, biogrid 51 34 6 6 0
STX10 STX10 O60499 Syntaxin-10 chr19 Not Cancer Driver No 1 hippie, biogrid 29 77 7 7 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX Not Cancer Driver No 1 hippie 379 1152 219 219 5
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 Census, Compendium Yes 1 hippie 106 60 16 16 25
THEM6 THEM6 Q8WUY1 Protein THEM6 chr8 Not Cancer Driver No 1 hippie, biogrid 3 7 0 0 0
TM9SF4 TM9SF4 Q92544 Transmembrane 9 superfamily member 4 chr20 Not Cancer Driver No 1 hippie, biogrid 76 39 4 4 0
TMC6 TMC6 Q7Z403 Transmembrane channel-like protein 6 chr17 Not Cancer Driver No 1 hippie, biogrid 72 129 9 9 0
TMEM131L_ENST00000409663 TMEM131L A2VDJ0 Transmembrane protein 131-like chr4 Not Cancer Driver No 1 hippie 188 448 47 47 0
TMEM30A TMEM30A Q9NV96 Cell cycle control protein 50A chr6 Not Cancer Driver No 1 hippie, biogrid 50 76 8 8 0
TMEM59 TMEM59 Q9BXS4 Transmembrane protein 59 chr1 Not Cancer Driver No 1 hippie, biogrid 39 26 3 3 0
TMEM59L_ENST00000262817 TMEM59L Q9UK28 Transmembrane protein 59-like chr19 Not Cancer Driver No 1 hippie, biogrid 58 80 15 15 0
TNFSF9 TNFSF9 P41273 Tumor necrosis factor ligand superfamily member 9 chr19 Not Cancer Driver No 1 hippie, biogrid 32 39 4 4 0
UBE3C UBE3C Q15386 Ubiquitin-protein ligase E3C chr7 Not Cancer Driver No 1 hippie, biogrid 143 65 12 12 0
UFSP2 UFSP2 Q9NUQ7 Ufm1-specific protease 2 chr4 Not Cancer Driver No 1 hippie, biogrid 53 22 3 3 2
XPO5 XPO5 Q9HAV4 Exportin-5 chr6 Not Cancer Driver No 1 hippie, biogrid 112 64 7 7 0