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SFPQ ,SFPQ ,P23246
  • Uniprot Accession= P23246
  • Ensembl Transcript= ENST00000357214.5
  • Uniprot Name= SFPQ
  • Name= Splicing factor, proline- and glutamine-rich
  • Chromosome= chr1
  • Driver status= Census
  • Number of Interaction partner in intact: 77
  • Number of Interaction partner in biogrid: 112
  • Number of Interaction partner in hippie: 386
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 56 28 6 6 0
ACAT1 ACAT1 P24752 Acetyl-CoA acetyltransferase, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 45 32 1 1 10
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 114 48 19 19 11
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 23 20 2 2 0
AHSA1 AHSA1 O95433 Activator of 90 kDa heat shock protein ATPase homolog 1 chr14 Not Cancer Driver No 1 hippie 46 146 17 17 0
ALYREF ALYREF Q86V81 THO complex subunit 4 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 32 223 26 26 0
ANG ANG P03950 Angiogenin chr14 Not Cancer Driver No 1 hippie 19 36 2 2 14
ANKRD50 ANKRD50 Q9ULJ7 Ankyrin repeat domain-containing protein 50 chr4 Not Cancer Driver No 1 hippie, biogrid 205 432 71 71 0
AP2M1_ENST00000292807 AP2M1 Q96CW1 AP-2 complex subunit mu chr3 Not Cancer Driver No 1 hippie 55 41 9 9 1
APBB1 APBB1 O00213 Amyloid beta precursor protein binding family B member 1 chr11 Not Cancer Driver No 1 hippie 105 399 58 58 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie, biogrid 34 103 14 14 0
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 196 443 88 88 169
ARMC12_ENST00000373866 ARMC12 Q5T9G4 Armadillo repeat-containing protein 12 chr6 Not Cancer Driver No 1 hippie 58 8 0 0 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 Not Cancer Driver No 1 hippie 46 122 22 22 0
ASB12 ASB12 Q8WXK4 Ankyrin repeat and SOCS box protein 12 chrX Not Cancer Driver No 1 hippie 77 21 3 3 0
ASB18 ASB18 Q6ZVZ8 Ankyrin repeat and SOCS box protein 18 chr2 Not Cancer Driver No 1 hippie 37 82 0 0 0
ASB3 ASB3 Q9Y575 Ankyrin repeat and SOCS box protein 3 chr2 Not Cancer Driver No 1 hippie 71 0 0 0 0
ATP11C ATP11C Q8NB49 Phospholipid-transporting ATPase IG chrX Not Cancer Driver No 1 intact, hippie 198 32 5 5 1
ATXN3 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 hippie 46 181 24 24 0
BCLAF1 BCLAF1 Q9NYF8 Bcl-2-associated transcription factor 1 chr6 Census, Compendium Yes 1 hippie 421 899 408 408 0
BIN1 BIN1 O00499 Myc box-dependent-interacting protein 1 chr2 Not Cancer Driver No 1 hippie 65 456 42 42 5
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 50 150 30 30 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BTF3 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie 27 192 24 24 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX Census, Compendium Yes 1 hippie 147 114 27 27 110
C8orf82 C8orf82 Q6P1X6 UPF0598 protein C8orf82 chr8 Not Cancer Driver No 1 hippie, biogrid 11 11 0 0 0
CBLL1 CBLL1 Q75N03 E3 ubiquitin-protein ligase Hakai chr7 Not Cancer Driver No 1 hippie 72 373 49 49 0
CCDC8 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 96 505 91 91 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie 106 221 23 23 3
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 Census Yes 1 hippie 29 54 9 9 0
CD2BP2 CD2BP2 O95400 CD2 antigen cytoplasmic tail-binding protein 2 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 49 259 40 40 0
CD81 CD81 P60033 CD81 antigen chr11 Not Cancer Driver No 1 hippie 28 0 0 0 0
CDC5L CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 4 intact, hippie, biogrid 100 618 77 77 0
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 24 0 0 0 0
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 Not Cancer Driver No 1 hippie 50 34 2 2 0
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 Census, Compendium Yes 1 hippie 12 342 12 12 1
CELF1_ENST00000358597 CELF1 Q92879 CUGBP Elav-like family member 1 chr11 Not Cancer Driver No 1 hippie 56 166 17 17 0
CEP55 CEP55 Q53EZ4 Centrosomal protein of 55 kDa chr10 Not Cancer Driver No 1 hippie 59 264 26 26 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 2 intact, hippie 287 145 18 18 151
CHD3_ENST00000330494 CHD3 Q12873 Chromodomain-helicase-DNA-binding protein 3 chr17 Not Cancer Driver No 1 hippie 235 1015 122 122 18
CHD4 CHD4 Q14839 Chromodomain-helicase-DNA-binding protein 4 chr12 Census, Compendium Yes 1 hippie 419 974 177 177 6
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 Census, Compendium Yes 1 intact, hippie 335 157 130 130 13
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 Not Cancer Driver No 1 hippie 25 201 22 22 2
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 224 31 31 0
CIC CIC Q96RK0 Protein capicua homolog chr19 Census, Compendium Yes 1 hippie 276 1550 266 266 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 36 32 7 7 0
COX5A COX5A P20674 Cytochrome c oxidase subunit 5A, mitochondrial chr15 Not Cancer Driver No 1 hippie, biogrid 20 14 5 5 1
CPSF7_ENST00000394888 CPSF7 Q8N684 Cleavage and polyadenylation specificity factor subunit 7 chr11 Not Cancer Driver No 1 hippie, biogrid 55 398 52 52 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 Not Cancer Driver No 2 intact, hippie 76 91 5 5 0
CSNK1E CSNK1E P49674 Casein kinase I isoform epsilon chr22 Not Cancer Driver No 1 hippie 62 133 18 18 0
CSNK2A1_ENST00000400217 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 Not Cancer Driver No 1 hippie 71 75 8 8 4
CTBP1 CTBP1 Q13363 C-terminal-binding protein 1 chr4 Not Cancer Driver No 2 intact, hippie 42 123 9 9 1
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
CTTN_ENST00000301843 CTTN Q14247 Src substrate cortactin chr11 Not Cancer Driver No 1 hippie 78 465 56 56 0
CUL4B CUL4B Q13620 Cullin-4B chrX Not Cancer Driver No 1 hippie 138 207 38 38 2
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 188 372 41 41 3
CYCS_ENST00000409409 CYCS P99999 Cytochrome c chr7 Not Cancer Driver No 1 hippie, biogrid 12 19 3 3 1
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
DCPS DCPS Q96C86 m7GpppX diphosphatase chr11 Not Cancer Driver No 1 hippie 48 53 6 6 1
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 34 181 23 23 0
DDX17_ENST00000640332 DDX17 Q92841 Probable ATP-dependent RNA helicase DDX17 chr22 Not Cancer Driver No 1 hippie, biogrid 91 362 48 48 0
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 Not Cancer Driver No 1 hippie, biogrid 72 342 30 30 0
DDX41 DDX41 Q9UJV9 Probable ATP-dependent RNA helicase DDX41 chr5 Not Cancer Driver No 1 hippie 82 180 26 26 1
DDX42 DDX42 Q86XP3 ATP-dependent RNA helicase DDX42 chr17 Not Cancer Driver No 1 hippie, biogrid 126 607 79 79 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DHPS DHPS P49366 Deoxyhypusine synthase chr19 Not Cancer Driver No 2 intact, hippie, biogrid 52 69 4 4 1
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 Compendium Yes 1 hippie 182 331 42 42 0
DICER1 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 Census, Compendium Yes 1 intact, hippie 264 362 45 45 4
DIDO1 DIDO1 Q9BTC0 Death-inducer obliterator 1 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 453 1917 400 400 0
DMRTB1 DMRTB1 Q96MA1 Doublesex- and mab-3-related transcription factor B1 chr1 Not Cancer Driver No 1 hippie 61 284 48 48 0
DNAJC19 DNAJC19 Q96DA6 Mitochondrial import inner membrane translocase subunit TIM14 chr3 Not Cancer Driver No 1 hippie, biogrid 19 27 6 6 0
DPH5 DPH5 Q9H2P9 Diphthine methyl ester synthase chr1 Not Cancer Driver No 1 hippie, biogrid 25 18 1 1 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 Not Cancer Driver No 1 hippie 135 447 73 73 0
EED_ENST00000263360 EED O75530 Polycomb protein EED chr11 Census Yes 1 hippie 64 79 11 11 6
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie, biogrid 132 179 30 30 3
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EIF3F_ENST00000309828 EIF3F O00303 Eukaryotic translation initiation factor 3 subunit F chr11 Not Cancer Driver No 1 hippie 29 125 8 8 1
EIF5A_ENST00000419711 EIF5A P63241 Eukaryotic translation initiation factor 5A-1 chr17 Not Cancer Driver No 1 hippie, biogrid 37 21 5 5 5
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 Not Cancer Driver No 1 hippie 211 829 117 117 9
ERG_ENST00000288319 ERG P11308 Transcriptional regulator ERG chr21 Census, Compendium Yes 1 hippie 95 296 54 54 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 2 intact, hippie 121 195 27 27 2
EWSR1_ENST00000397938 EWSR1 Q01844 RNA-binding protein EWS chr22 Census, Compendium Yes 2 intact, hippie, biogrid 94 646 93 93 0
EXOSC5 EXOSC5 Q9NQT4 Exosome complex component RRP46 chr19 Not Cancer Driver No 1 intact, hippie 43 31 3 3 0
EXOSC8 EXOSC8 Q96B26 Exosome complex component RRP43 chr13 Not Cancer Driver No 1 hippie 20 28 1 1 2
FABP4 FABP4 P15090 Fatty acid-binding protein, adipocyte chr8 Not Cancer Driver No 1 hippie 14 4 0 0 0
FAM76B FAM76B Q5HYJ3 Protein FAM76B chr11 Not Cancer Driver No 1 hippie, biogrid 38 194 23 23 0
FAM98A FAM98A Q8NCA5 Protein FAM98A chr2 Not Cancer Driver No 1 intact, hippie, biogrid 63 314 36 36 0
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 176 181 14 14 3
FBP1_ENST00000375326 FBP1 P09467 Fructose-1,6-bisphosphatase 1 chr9 Not Cancer Driver No 1 hippie 33 19 0 0 4
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie 322 230 38 38 0
FGF11 FGF11 Q92914 Fibroblast growth factor 11 chr17 Not Cancer Driver No 1 hippie 20 68 5 5 0
FHL2_ENST00000408995 FHL2 Q14192 Four and a half LIM domains protein 2 chr2 Not Cancer Driver No 1 hippie 30 0 0 0 0
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX Not Cancer Driver No 2 intact, hippie 124 327 70 70 3
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 hippie 394 1243 185 185 8
FUS FUS P35637 RNA-binding protein FUS chr16 Census Yes 2 intact, hippie, biogrid 51 524 51 51 20
FXR1 FXR1 P51114 Fragile X mental retardation syndrome-related protein 1 chr3 Not Cancer Driver No 1 intact, hippie 88 312 53 53 0
FXR2 FXR2 P51116 Fragile X mental retardation syndrome-related protein 2 chr17 Not Cancer Driver No 1 intact, hippie 68 388 42 42 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 74 184 30 30 0
GABARAP GABARAP O95166 Gamma-aminobutyric acid receptor-associated protein chr17 Not Cancer Driver No 1 hippie 9 11 0 0 0
GABARAPL1_ENST00000545887 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 19 10 1 1 0
GABARAPL2 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 Not Cancer Driver No 1 hippie 11 2 1 1 0
GAS7 GAS7 O60861 Growth arrest-specific protein 7 chr17 Census Yes 1 hippie 78 318 57 57 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 Not Cancer Driver No 1 intact, hippie 56 146 13 13 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 1 hippie 47 135 10 10 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 hippie 46 145 14 14 0
HDAC5_ENST00000586802 HDAC5 Q9UQL6 Histone deacetylase 5 chr17 Not Cancer Driver No 1 hippie 118 718 73 73 0
HECTD1 HECTD1 Q9ULT8 E3 ubiquitin-protein ligase HECTD1 chr14 Not Cancer Driver No 1 hippie 274 991 108 108 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 40 352 40 40 0
HIP1R HIP1R O75146 Huntingtin-interacting protein 1-related protein chr12 Not Cancer Driver No 2 intact, hippie, biogrid 94 524 34 34 0
HNF4A HNF4A P41235 Hepatocyte nuclear factor 4-alpha chr20 Not Cancer Driver No 1 hippie 135 127 48 48 5
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 Not Cancer Driver No 4 intact, hippie, biogrid 70 290 58 58 4
HNRNPA2B1 HNRNPA2B1 P22626 Heterogeneous nuclear ribonucleoproteins A2/B1 chr7 Census, Compendium Yes 1 hippie, biogrid 68 255 41 41 0
HNRNPA3 HNRNPA3 P51991 Heterogeneous nuclear ribonucleoprotein A3 chr2 Not Cancer Driver No 1 hippie, biogrid 46 285 37 37 0
HNRNPC_ENST00000420743 HNRNPC P07910 Heterogeneous nuclear ribonucleoproteins C1/C2 chr14 Not Cancer Driver No 1 hippie, biogrid 42 227 35 35 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 Not Cancer Driver No 1 hippie, biogrid 39 206 19 19 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie, biogrid 89 283 29 29 0
HNRNPM HNRNPM P52272 Heterogeneous nuclear ribonucleoprotein M chr19 Not Cancer Driver No 1 hippie, biogrid 108 463 67 67 0
HNRNPR_ENST00000374612 HNRNPR O43390 Heterogeneous nuclear ribonucleoprotein R chr1 Not Cancer Driver No 1 hippie, biogrid 67 304 25 25 0
HTATSF1_ENST00000218364 HTATSF1 O43719 HIV Tat-specific factor 1 chrX Not Cancer Driver No 1 hippie, biogrid 131 573 100 100 0
HTR7 HTR7 P34969 5-hydroxytryptamine receptor 7 chr10 Not Cancer Driver No 1 intact, hippie 102 24 1 1 0
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 669 2091 329 329 21
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 Not Cancer Driver No 1 hippie 155 419 90 90 0
IGFBP3_ENST00000275521 IGFBP3 P17936 Insulin-like growth factor-binding protein 3 chr7 Not Cancer Driver No 1 hippie 41 103 25 25 0
ILF3_ENST00000590261 ILF3 Q12906 Interleukin enhancer-binding factor 3 chr19 Not Cancer Driver No 1 hippie, biogrid 103 674 82 82 0
IMMT IMMT Q16891 MICOS complex subunit MIC60 chr2 Not Cancer Driver No 1 hippie, biogrid 97 400 50 50 0
INS INS P01308 Insulin chr11 Not Cancer Driver No 1 hippie 15 5 1 1 22
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 Not Cancer Driver No 1 hippie 254 97 27 27 0
JMJD6_ENST00000397625 JMJD6 Q6NYC1 Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 chr17 Not Cancer Driver No 1 hippie 51 133 21 21 0
JPT1_ENST00000409753 JPT1 Q9UK76 Jupiter microtubule associated homolog 1 chr17 Not Cancer Driver No 1 intact, hippie 18 154 18 18 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KDF1 KDF1 Q8NAX2 Keratinocyte differentiation factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 61 277 50 50 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 Not Cancer Driver No 1 intact, hippie 67 291 28 28 3
KHDRBS1 KHDRBS1 Q07666 KH domain-containing, RNA-binding, signal transduction-associated protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 53 362 43 43 0
KIAA0556 KATNIP O60303 Katanin-interacting protein chr16 Not Cancer Driver No 1 intact 240 982 137 137 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 102 559 62 62 0
KRT31 KRT31 Q15323 Keratin, type I cuticular Ha1 chr17 Not Cancer Driver No 1 hippie 116 64 16 16 0
L1TD1 L1TD1 Q5T7N2 LINE-1 type transposase domain-containing protein 1 chr1 Not Cancer Driver No 1 intact, hippie 149 534 114 114 0
LAMTOR5_ENST00000602318 LAMTOR5 O43504 Ragulator complex protein LAMTOR5 chr1 Not Cancer Driver No 1 intact, hippie 10 17 0 0 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 58 350 44 44 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 Not Cancer Driver No 1 hippie 54 65 16 16 0
LMNA LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie 68 544 49 49 131
LMO7_ENST00000357063 LMO7 Q8WWI1 LIM domain only protein 7 chr13 Not Cancer Driver No 1 hippie, biogrid 267 1102 188 188 0
LONP1 LONP1 P36776 Lon protease homolog, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 99 175 15 15 10
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
LSM14A_ENST00000433627 LSM14A Q8ND56 Protein LSM14 homolog A chr19 Census Yes 2 hippie, biogrid 67 408 63 63 0
MAB21L2 MAB21L2 Q9Y586 Protein mab-21-like 2 chr4 Not Cancer Driver No 1 intact, hippie 81 6 3 3 5
MAP1LC3A_ENST00000397709 MAP1LC3A Q9H492 Microtubule-associated proteins 1A/1B light chain 3A chr20 Not Cancer Driver No 1 hippie 22 24 1 1 0
MAP1LC3B MAP1LC3B Q9GZQ8 Microtubule-associated proteins 1A/1B light chain 3B chr16 Not Cancer Driver No 1 intact, hippie 10 17 1 1 0
MAP3K14 MAP3K14 Q99558 Mitogen-activated protein kinase kinase kinase 14 chr17 Not Cancer Driver No 1 intact, hippie 94 543 52 52 0
MAPK13 MAPK13 O15264 Mitogen-activated protein kinase 13 chr6 Not Cancer Driver No 1 intact, hippie 51 50 15 15 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 hippie 62 2 0 0 7
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 128 750 126 126 18
MATR3_ENST00000509990 MATR3 P43243 Matrin-3 chr5 Not Cancer Driver No 1 hippie 98 611 68 68 3
MAU2 MAU2 Q9Y6X3 MAU2 chromatid cohesion factor homolog chr19 Not Cancer Driver No 1 hippie 68 36 1 1 0
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 104 275 38 38 1
MCM5 MCM5 P33992 DNA replication licensing factor MCM5 chr22 Not Cancer Driver No 1 hippie 88 109 20 20 1
MDC1 MDC1 Q14676 Mediator of DNA damage checkpoint protein 1 chr6 Not Cancer Driver No 1 hippie 249 1829 223 223 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 56 297 37 37 0
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 Not Cancer Driver No 2 hippie, biogrid 76 446 42 42 0
METTL14 METTL14 Q9HCE5 N6-adenosine-methyltransferase non-catalytic subunit chr4 Not Cancer Driver No 1 hippie 60 224 26 26 0
METTL17_ENST00000339374 METTL17 Q9H7H0 Methyltransferase-like protein 17, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 62 95 16 16 0
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 Not Cancer Driver No 1 hippie 74 274 29 29 0
MKRN1 MKRN1 Q9UHC7 E3 ubiquitin-protein ligase makorin-1 chr7 Not Cancer Driver No 1 hippie 42 155 16 16 0
MMADHC_ENST00000303319 MMADHC Q9H3L0 Cobalamin trafficking protein CblD chr2 Not Cancer Driver No 2 hippie, biogrid 31 65 8 8 3
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MTHFS MTHFS P49914 5-formyltetrahydrofolate cyclo-ligase chr15 Not Cancer Driver No 1 hippie 18 36 6 6 2
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NCL NCL P19338 Nucleolin chr2 Not Cancer Driver No 1 intact, hippie 85 569 68 68 0
NCOA5 NCOA5 Q9HCD5 Nuclear receptor coactivator 5 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 84 478 70 70 0
NDC80 NDC80 O14777 Kinetochore protein NDC80 homolog chr18 Not Cancer Driver No 1 hippie, biogrid 80 313 45 45 0
NDN NDN Q99608 Necdin chr15 Not Cancer Driver No 1 intact, hippie 123 117 42 42 0
NDUFS3 NDUFS3 O75489 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 34 26 3 3 2
NEK4 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 Not Cancer Driver No 1 hippie 78 492 49 49 0
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 Not Cancer Driver No 1 hippie 104 344 38 38 0
NFKB2 NFKB2 Q00653 Nuclear factor NF-kappa-B p100 subunit chr10 Census, Compendium Yes 1 intact, hippie 86 510 46 46 0
NFKBIB NFKBIB Q15653 NF-kappa-B inhibitor beta chr19 Not Cancer Driver No 1 intact, hippie 42 223 29 29 0
NFKBIE NFKBIE O00221 NF-kappa-B inhibitor epsilon chr6 Census, Compendium Yes 1 hippie 41 284 16 16 0
NKX2-1_ENST00000518149 NKX2-1 P43699 Homeobox protein Nkx-2.1 chr14 Census, Compendium Yes 1 hippie 41 334 39 39 7
NONO NONO Q15233 Non-POU domain-containing octamer-binding protein chrX Census, Compendium Yes 9 intact, hippie, biogrid 101 349 64 64 0
NR2C1 NR2C1 P13056 Nuclear receptor subfamily 2 group C member 1 chr12 Not Cancer Driver No 1 hippie 65 156 13 13 0
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
NR4A2_ENST00000409572 NR4A2 P43354 Nuclear receptor subfamily 4 group A member 2 chr2 Not Cancer Driver No 1 hippie 110 261 38 38 0
NSD2_ENST00000382892 NSD2 O96028 Histone-lysine N-methyltransferase NSD2 chr4 Census, Compendium Yes 1 hippie 191 552 76 76 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NUDT21 NUDT21 O43809 Cleavage and polyadenylation specificity factor subunit 5 chr16 Not Cancer Driver No 1 hippie, biogrid 21 37 3 3 0
NUFIP2 NUFIP2 Q7Z417 Nuclear fragile X mental retardation-interacting protein 2 chr17 Not Cancer Driver No 1 hippie, biogrid 67 623 62 62 0
NUP210 NUP210 Q8TEM1 Nuclear pore membrane glycoprotein 210 chr3 Not Cancer Driver No 1 hippie, biogrid 262 156 19 19 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 233 553 60 60 0
OCRL OCRL Q01968 Inositol polyphosphate 5-phosphatase OCRL chrX Not Cancer Driver No 1 hippie 151 126 24 24 41
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX Not Cancer Driver No 1 hippie 156 89 16 16 2
ORC6 ORC6 Q9Y5N6 Origin recognition complex subunit 6 chr16 Not Cancer Driver No 1 hippie, biogrid 23 69 10 10 1
PAK4 PAK4 O96013 Serine/threonine-protein kinase PAK 4 chr19 Not Cancer Driver No 1 hippie 58 340 33 33 0
PAN2_ENST00000548043 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 Not Cancer Driver No 1 hippie 139 78 10 10 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 Not Cancer Driver No 1 hippie 11 30 0 0 5
PAWR PAWR Q96IZ0 PRKC apoptosis WT1 regulator protein chr12 Not Cancer Driver No 1 hippie 35 327 33 33 0
PCBP1 PCBP1 Q15365 Poly(rC)-binding protein 1 chr2 Census, Compendium Yes 1 hippie 65 166 24 24 0
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PEG10_ENST00000617526 PEG10 Q86TG7 Retrotransposon-derived protein PEG10 chr7 Not Cancer Driver No 1 hippie 94 246 47 47 0
PER2 PER2 O15055 Period circadian protein homolog 2 chr2 Not Cancer Driver No 1 hippie 166 782 101 101 1
PFKM_ENST00000550924 PFKM P08237 ATP-dependent 6-phosphofructokinase, muscle type chr12 Not Cancer Driver No 1 hippie, biogrid 80 70 8 8 9
PGK1 PGK1 P00558 Phosphoglycerate kinase 1 chrX Not Cancer Driver No 1 hippie, biogrid 61 40 5 5 9
PGR PGR P06401 Progesterone receptor chr11 Not Cancer Driver No 1 intact, hippie 161 480 55 55 0
PHF5A PHF5A Q7RTV0 PHD finger-like domain-containing protein 5A chr22 Not Cancer Driver No 1 hippie, biogrid 20 0 0 0 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 1 hippie 154 268 61 61 2
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 Not Cancer Driver No 1 hippie 17 115 12 12 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie 57 99 13 13 23
PITX3_ENST00000539804 PITX3 O75364 Pituitary homeobox 3 chr10 Not Cancer Driver No 1 hippie 24 155 12 12 1
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLEKHA7 PLEKHA7 Q6IQ23 Pleckstrin homology domain-containing family A member 7 chr11 Not Cancer Driver No 1 intact, hippie 152 919 121 121 0
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 Census, Compendium Yes 1 hippie 113 31 6 6 9
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 Census Yes 1 hippie 72 44 4 4 3
PPARGC1A PPARGC1A Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha chr4 Not Cancer Driver No 1 hippie 181 609 148 148 0
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 Not Cancer Driver No 1 hippie 11 24 3 3 0
PPIL4 PPIL4 Q8WUA2 Peptidyl-prolyl cis-trans isomerase-like 4 chr6 Not Cancer Driver No 1 hippie, biogrid 62 237 34 34 0
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 1 hippie 38 27 6 6 0
PPP1R10 PPP1R10 Q96QC0 Serine/threonine-protein phosphatase 1 regulatory subunit 10 chr6 Not Cancer Driver No 1 hippie, biogrid 114 798 100 100 0
PRC1 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 Not Cancer Driver No 1 hippie 63 235 26 26 0
PRKCI PRKCI P41743 Protein kinase C iota type chr3 Not Cancer Driver No 1 hippie 110 120 16 16 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 Census Yes 1 hippie 201 189 33 33 2
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 Not Cancer Driver No 1 hippie 538 421 61 61 2
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 110 78 15 15 31
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 Not Cancer Driver No 1 intact, hippie, biogrid 83 72 6 6 0
PRPF40A PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 hippie 83 694 57 57 0
PRPF8 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie 255 225 26 26 8
PRRC2A_ENST00000376007 PRRC2A P48634 Protein PRRC2A chr6 Not Cancer Driver No 2 intact, hippie, biogrid 253 2119 249 249 0
PRRC2C PRRC2C Q9Y520-4 Isoform 4 of Protein PRRC2C chr1 Not Cancer Driver No 1 intact, hippie, biogrid 296 2713 287 287 0
PSMA3 PSMA3 P25788 Proteasome subunit alpha type-3 chr14 Not Cancer Driver No 1 hippie 27 30 5 5 0
PSPC1_ENST00000619300 PSPC1 Q8WXF1 Paraspeckle component 1 chr13 Not Cancer Driver No 5 intact, hippie, biogrid 97 367 81 81 0
PTBP1_ENST00000349038 PTBP1 P26599 Polypyrimidine tract-binding protein 1 chr19 Not Cancer Driver No 3 intact, hippie 74 154 17 17 0
PTK6 PTK6 Q13882 Protein-tyrosine kinase 6 chr20 Census Yes 1 hippie 42 12 0 0 0
PTP4A3_ENST00000521578 PTP4A3 O75365 Protein tyrosine phosphatase type IVA 3 chr8 Not Cancer Driver No 1 hippie, biogrid 30 3 0 0 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 intact, hippie 66 2 1 1 6
RAD21 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 Census, Compendium Yes 1 hippie 115 421 74 74 3
RAD51D_ENST00000394589 RAD51D O75771 DNA repair protein RAD51 homolog 4 chr17 Not Cancer Driver No 1 hippie 34 49 10 10 0
RBM27 RBM27 Q9P2N5 RNA-binding protein 27 chr5 Not Cancer Driver No 1 hippie, biogrid 139 931 127 127 0
RBM39 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 81 228 39 39 0
RBM45_ENST00000616198 RBM45 Q8IUH3 RNA-binding protein 45 chr2 Not Cancer Driver No 1 hippie 56 105 20 20 0
RBMXL1 RBMXL1 Q96E39 RNA binding motif protein, X-linked-like-1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 77 371 75 75 0
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 Not Cancer Driver No 1 hippie 158 796 115 115 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RELA RELA Q04206 Transcription factor p65 chr11 Compendium Yes 1 intact, hippie 75 400 48 48 0
RELB RELB Q01201 Transcription factor RelB chr19 Not Cancer Driver No 1 intact, hippie 65 348 39 39 0
REST REST Q13127 RE1-silencing transcription factor chr4 Not Cancer Driver No 1 hippie 142 868 113 113 4
RIOK1 RIOK1 Q9BRS2 Serine/threonine-protein kinase RIO1 chr6 Not Cancer Driver No 1 hippie 69 301 37 37 0
RIOK2 RIOK2 Q9BVS4 Serine/threonine-protein kinase RIO2 chr5 Not Cancer Driver No 1 hippie 68 253 33 33 0
RNF123 RNF123 Q5XPI4 E3 ubiquitin-protein ligase RNF123 chr3 Not Cancer Driver No 1 hippie 167 220 28 28 0
RNF144A RNF144A P50876 E3 ubiquitin-protein ligase RNF144A chr2 Not Cancer Driver No 1 hippie 63 0 0 0 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
RNF43_ENST00000577716 RNF43 Q68DV7 E3 ubiquitin-protein ligase RNF43 chr17 Census, Compendium Yes 1 intact, hippie 121 437 54 54 0
RPA1 RPA1 P27694 Replication protein A 70 kDa DNA-binding subunit chr17 Not Cancer Driver No 1 hippie 51 98 6 6 0
RPA2_ENST00000373912 RPA2 P15927 Replication protein A 32 kDa subunit chr1 Not Cancer Driver No 1 hippie 28 114 16 16 0
RPA3 RPA3 P35244 Replication protein A 14 kDa subunit chr7 Not Cancer Driver No 1 hippie 13 4 1 1 0
RPL23A RPL23A P62750 60S ribosomal protein L23a chr17 Not Cancer Driver No 1 hippie, biogrid 21 70 13 13 0
RPS19_ENST00000600467 RPS19 P39019 40S ribosomal protein S19 chr19 Not Cancer Driver No 1 hippie, biogrid 15 61 3 3 23
RPS6KB2 RPS6KB2 Q9UBS0 Ribosomal protein S6 kinase beta-2 chr11 Not Cancer Driver No 1 hippie 54 194 16 16 0
RRP1B RRP1B Q14684 Ribosomal RNA processing protein 1 homolog B chr21 Not Cancer Driver No 1 intact, hippie 74 513 48 48 0
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 Census, Compendium Yes 1 hippie 81 360 58 58 2
SART1 SART1 O43290 U4/U6.U5 tri-snRNP-associated protein 1 chr11 Not Cancer Driver No 2 hippie, biogrid 71 685 63 63 0
SCARB2 SCARB2 Q14108 Lysosome membrane protein 2 chr4 Not Cancer Driver No 1 hippie 61 13 3 3 1
SERBP1 SERBP1 Q8NC51 Plasminogen activator inhibitor 1 RNA-binding protein chr1 Not Cancer Driver No 1 hippie, biogrid 53 408 53 53 0
SF1_ENST00000377390 SF1 Q15637 Splicing factor 1 chr11 Not Cancer Driver No 1 intact, hippie, biogrid 110 627 106 106 0
SF3A1 SF3A1 Q15459 Splicing factor 3A subunit 1 chr22 Not Cancer Driver No 1 hippie, biogrid 82 631 67 67 0
SF3B1 SF3B1 O75533 Splicing factor 3B subunit 1 chr2 Census, Compendium Yes 1 hippie, biogrid 244 477 80 80 0
SF3B3 SF3B3 Q15393 Splicing factor 3B subunit 3 chr16 Not Cancer Driver No 1 hippie, biogrid 154 145 19 19 0
SF3B4 SF3B4 Q15427 Splicing factor 3B subunit 4 chr1 Not Cancer Driver No 1 hippie 69 273 56 56 0
SFN SFN P31947 14-3-3 protein sigma chr1 Not Cancer Driver No 1 hippie 27 75 9 9 0
SFPQ SFPQ P23246 Splicing factor, proline- and glutamine-rich chr1 Census Yes 1 intact, hippie, biogrid 59 595 48 48 0
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 Compendium Yes 1 intact, hippie 172 617 73 73 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 48 163 15 15 0
SLC12A2 SLC12A2 P55011 Solute carrier family 12 member 2 chr5 Not Cancer Driver No 1 hippie 141 297 18 18 8
SLFN11_ENST00000308377 SLFN11 Q7Z7L1 Schlafen family member 11 chr17 Not Cancer Driver No 1 hippie 177 34 8 8 0
SLTM SLTM Q9NWH9 SAFB-like transcription modulator chr15 Not Cancer Driver No 1 hippie, biogrid 110 962 103 103 0
SMAD5_ENST00000509297 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 Not Cancer Driver No 1 intact, hippie 44 172 11 11 0
SMARCA2 SMARCA2 P51531 Probable global transcription activator SNF2L2 chr9 Not Cancer Driver No 1 hippie 273 1009 160 160 42
SMARCA5 SMARCA5 O60264 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 chr4 Not Cancer Driver No 1 hippie, biogrid 116 363 48 48 0
SMARCC1 SMARCC1 Q92922 SWI/SNF complex subunit SMARCC1 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 125 720 81 81 0
SMARCC2_ENST00000267064 SMARCC2 Q8TAQ2 SWI/SNF complex subunit SMARCC2 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 175 876 133 133 4
SMARCD1 SMARCD1 Q96GM5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 chr12 Census, Compendium Yes 1 hippie 48 216 18 18 2
SMC3 SMC3 Q9UQE7 Structural maintenance of chromosomes protein 3 chr10 Not Cancer Driver No 1 hippie, biogrid 149 605 70 70 0
SMN1_ENST00000503079 SMN1 Q16637-2 Isoform SMN-delta5 of Survival motor neuron protein chr5 Not Cancer Driver No 1 intact, hippie 2 181 2 2 0
SND1 SND1 Q7KZF4 Staphylococcal nuclease domain-containing protein 1 chr7 Census Yes 1 hippie, biogrid 127 258 48 48 0
SNIP1 SNIP1 Q8TAD8 Smad nuclear-interacting protein 1 chr1 Not Cancer Driver No 1 intact, hippie 58 285 40 40 1
SNRNP70 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 Not Cancer Driver No 1 intact, hippie 38 416 37 37 0
SNRPA SNRPA P09012 U1 small nuclear ribonucleoprotein A chr19 Not Cancer Driver No 1 intact, hippie 44 164 24 24 0
SNRPA1 SNRPA1 P09661 U2 small nuclear ribonucleoprotein A' chr15 Not Cancer Driver No 1 hippie, biogrid 33 93 14 14 0
SNRPD2_ENST00000588301 SNRPD2 P62316 Small nuclear ribonucleoprotein Sm D2 chr19 Not Cancer Driver No 1 hippie, biogrid 19 67 12 12 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie 62 488 56 56 0
SON SON P18583 Protein SON chr21 Not Cancer Driver No 1 hippie, biogrid 234 2109 212 212 0
SP1 SP1 P08047 Transcription factor Sp1 chr12 Not Cancer Driver No 1 hippie 96 599 71 71 0
SP100_ENST00000264052 SP100 P23497 Nuclear autoantigen Sp-100 chr2 Not Cancer Driver No 1 hippie, biogrid 136 680 101 101 0
SP3 SP3 Q02447 Transcription factor Sp3 chr2 Not Cancer Driver No 1 hippie 66 587 37 37 0
SPOP SPOP O43791 Speckle-type POZ protein chr17 Census, Compendium Yes 1 hippie 147 25 5 5 6
SREK1_ENST00000380918 SREK1 Q8WXA9 Splicing regulatory glutamine/lysine-rich protein 1 chr5 Not Cancer Driver No 1 hippie 60 438 53 53 0
SRRM1 SRRM1 Q8IYB3 Serine/arginine repetitive matrix protein 1 chr1 Not Cancer Driver No 1 hippie 129 795 122 122 0
SRRM2 SRRM2 Q9UQ35 Serine/arginine repetitive matrix protein 2 chr16 Not Cancer Driver No 1 hippie 433 2748 431 431 0
SRSF3_ENST00000620941 SRSF3 P84103 Serine/arginine-rich splicing factor 3 chr6 Census Yes 1 hippie, biogrid 31 125 27 27 0
SRSF4 SRSF4 Q08170 Serine/arginine-rich splicing factor 4 chr1 Not Cancer Driver No 1 hippie, biogrid 67 409 55 55 0
SRSF5_ENST00000557154 SRSF5 Q13243 Serine/arginine-rich splicing factor 5 chr14 Not Cancer Driver No 1 hippie, biogrid 50 189 40 40 0
SRSF7 SRSF7 Q16629 Serine/arginine-rich splicing factor 7 chr2 Not Cancer Driver No 1 hippie, biogrid 40 175 26 26 0
SSR4_ENST00000370086 SSR4 P51571 Translocon-associated protein subunit delta chrX Not Cancer Driver No 1 hippie, biogrid 21 0 0 0 0
STAG2_ENST00000371157 STAG2 Q8N3U4 Cohesin subunit SA-2 chrX Census, Compendium Yes 1 hippie, biogrid 179 330 46 46 3
STAT6_ENST00000543873 STAT6 P42226 Signal transducer and activator of transcription 6 chr12 Census, Compendium Yes 1 hippie 106 325 44 44 0
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SUMO3_ENST00000332859 SUMO3 P55854 Small ubiquitin-related modifier 3 chr21 Not Cancer Driver No 1 hippie 7 87 5 5 0
SYNCRIP SYNCRIP O60506 Heterogeneous nuclear ribonucleoprotein Q chr6 Not Cancer Driver No 2 intact, hippie, biogrid 93 285 39 39 0
TAGLN3 TAGLN3 Q9UI15 Transgelin-3 chr3 Not Cancer Driver No 1 hippie 25 85 18 18 0
TARDBP TARDBP Q13148 TAR DNA-binding protein 43 chr1 Not Cancer Driver No 1 hippie 51 202 15 15 27
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 Not Cancer Driver No 1 intact, hippie 101 42 5 5 12
TCERG1 TCERG1 O14776 Transcription elongation regulator 1 chr5 Not Cancer Driver No 2 hippie, biogrid 143 811 110 110 0
TFIP11_ENST00000407148 TFIP11 Q9UBB9 Tuftelin-interacting protein 11 chr22 Not Cancer Driver No 1 hippie 87 331 39 39 0
THRAP3_ENST00000469141 THRAP3 Q9Y2W1 Thyroid hormone receptor-associated protein 3 chr1 Census Yes 2 hippie, biogrid 137 955 137 137 0
TIMM10_ENST00000525587 TIMM10 P62072 Mitochondrial import inner membrane translocase subunit Tim10 chr11 Not Cancer Driver No 1 hippie, biogrid 6 43 6 6 0
TIMM9_ENST00000555593 TIMM9 Q9Y5J7 Mitochondrial import inner membrane translocase subunit Tim9 chr14 Not Cancer Driver No 1 hippie, biogrid 9 8 1 1 0
TMEM14B_ENST00000379542 TMEM14B Q9NUH8 Transmembrane protein 14B chr6 Not Cancer Driver No 1 hippie, biogrid 13 0 0 0 0
TNF TNF P01375 Tumor necrosis factor chr6 Not Cancer Driver No 1 hippie 24 45 3 3 0
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 43 316 36 36 0
TNRC6A TNRC6A Q8NDV7 Trinucleotide repeat-containing gene 6A protein chr16 Not Cancer Driver No 1 hippie 284 1830 265 265 0
TOMM40_ENST00000405636 TOMM40 O96008 Mitochondrial import receptor subunit TOM40 homolog chr19 Not Cancer Driver No 1 hippie, biogrid 17 98 1 1 0
TOP1 TOP1 P11387 DNA topoisomerase 1 chr20 Census, Compendium Yes 2 hippie, biogrid 93 391 53 53 0
TOP2B TOP2B Q02880 DNA topoisomerase 2-beta chr3 Not Cancer Driver No 1 hippie, biogrid 154 543 46 46 0
TOPORS TOPORS Q9NS56 E3 ubiquitin-protein ligase Topors chr9 Not Cancer Driver No 1 hippie 149 795 105 105 0
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 Not Cancer Driver No 1 intact, hippie 227 1632 190 190 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TPR TPR P12270 Nucleoprotein TPR chr1 Census Yes 2 hippie, biogrid 311 1990 266 266 0
TRAF1 TRAF1 Q13077 TNF receptor-associated factor 1 chr9 Not Cancer Driver No 1 intact, hippie 51 63 9 9 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM37 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 Not Cancer Driver No 1 hippie 119 492 60 60 3
TRIM68 TRIM68 Q6AZZ1 E3 ubiquitin-protein ligase TRIM68 chr11 Not Cancer Driver No 1 hippie, biogrid 74 37 7 7 0
TSC1 TSC1 Q92574 Hamartin chr9 Census, Compendium Yes 1 intact, hippie 135 732 78 78 11
TSG101 TSG101 Q99816 Tumor susceptibility gene 101 protein chr11 Not Cancer Driver No 1 hippie 46 159 23 23 0
TSPYL5 TSPYL5 Q86VY4 Testis-specific Y-encoded-like protein 5 chr8 Not Cancer Driver No 1 intact, hippie, biogrid 92 257 61 61 0
TXN TXN P10599 Thioredoxin chr9 Not Cancer Driver No 1 hippie, biogrid 6 0 0 0 0
U2AF1 U2AF1 Q01081 Splicing factor U2AF 35 kDa subunit chr21 Census, Compendium Yes 1 hippie, biogrid 70 73 13 13 3
U2AF2 U2AF2 P26368 Splicing factor U2AF 65 kDa subunit chr19 Compendium Yes 2 hippie, biogrid 78 191 28 28 0
UBB_ENST00000614404 UBB P0CG47 Polyubiquitin-B chr17 Not Cancer Driver No 1 intact, hippie 20 102 8 8 0
UBC UBC P0CG48 Polyubiquitin-C chr12 Not Cancer Driver No 1 biogrid 97 312 53 53 0
UBD UBD O15205 Ubiquitin D chr6 Not Cancer Driver No 1 hippie 31 8 1 1 0
UBE2A UBE2A P49459 Ubiquitin-conjugating enzyme E2 A chrX Compendium Yes 1 hippie 35 67 13 13 2
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 Not Cancer Driver No 1 hippie 16 16 3 3 0
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 hippie 30 32 6 6 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
UNK UNK Q9C0B0 RING finger protein unkempt homolog chr17 Not Cancer Driver No 1 hippie 79 511 46 46 0
UQCRC2 UQCRC2 P22695 Cytochrome b-c1 complex subunit 2, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 53 48 13 13 1
USP14 USP14 P54578 Ubiquitin carboxyl-terminal hydrolase 14 chr18 Not Cancer Driver No 1 hippie 59 86 6 6 0
UTP14A UTP14A Q9BVJ6 U3 small nucleolar RNA-associated protein 14 homolog A chrX Not Cancer Driver No 1 hippie, biogrid 105 629 89 89 0
UTP20 UTP20 O75691 Small subunit processome component 20 homolog chr12 Not Cancer Driver No 1 intact, hippie 324 314 35 35 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 intact, hippie 188 110 28 28 0
VIM_ENST00000224237 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 hippie 84 316 57 57 1
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VRK1 VRK1 Q99986 Serine/threonine-protein kinase VRK1 chr14 Not Cancer Driver No 1 hippie 52 80 9 9 0
VTN VTN P04004 Vitronectin chr17 Not Cancer Driver No 1 hippie, biogrid 76 168 29 29 0
WAPL_ENST00000618527 WAPL Q7Z5K2 Wings apart-like protein homolog chr10 Not Cancer Driver No 1 hippie 140 621 68 68 0
WBP11 WBP11 Q9Y2W2 WW domain-binding protein 11 chr12 Not Cancer Driver No 1 hippie, biogrid 86 606 79 79 0
WBP4 WBP4 O75554 WW domain-binding protein 4 chr13 Not Cancer Driver No 1 intact, hippie 44 309 37 37 0
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 30 35 3 3 0
WDR7 WDR7 Q9Y4E6 WD repeat-containing protein 7 chr18 Not Cancer Driver No 1 intact, hippie 199 292 37 37 0
WDR76 WDR76 Q9H967 WD repeat-containing protein 76 chr15 Not Cancer Driver No 1 hippie 60 288 33 33 0
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 intact, hippie 79 108 9 9 3
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 Not Cancer Driver No 1 hippie 66 140 12 12 0
YLPM1 YLPM1 P49750 YLP motif-containing protein 1 chr14 Not Cancer Driver No 1 hippie 251 1985 226 226 0
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 67 376 44 44 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 hippie 32 41 3 3 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 1 intact, hippie 26 77 9 9 2
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 1 hippie 30 81 10 10 0
ZC3H18_ENST00000301011 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 1 hippie 139 929 134 134 0
ZC3HAV1 ZC3HAV1 Q7Z2W4 Zinc finger CCCH-type antiviral protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 142 344 63 63 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 Not Cancer Driver No 1 hippie 73 324 45 45 0
ZFYVE21_ENST00000311141 ZFYVE21 Q9BQ24 Zinc finger FYVE domain-containing protein 21 chr14 Not Cancer Driver No 1 hippie 28 19 0 0 0
ZMYM2_ENST00000382871 ZMYM2 Q9UBW7 Zinc finger MYM-type protein 2 chr13 Census Yes 1 hippie 144 583 68 68 0
ZNF263 ZNF263 O14978 Zinc finger protein 263 chr16 Not Cancer Driver No 1 hippie 90 403 58 58 0
ZNF746_ENST00000340622 ZNF746 Q6NUN9 Zinc finger protein 746 chr7 Not Cancer Driver No 1 hippie 93 436 56 56 0