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SFN ,SFN ,P31947
  • Uniprot Accession= P31947
  • Ensembl Transcript= ENST00000339276.5
  • Uniprot Name= SFN
  • Name= 14-3-3 protein sigma
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 1
  • Number of Interaction partner in biogrid: 69
  • Number of Interaction partner in hippie: 378
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 Census, Compendium Yes 1 hippie 139 604 73 73 2
ABLIM1 ABLIM1 O14639 Actin-binding LIM protein 1 chr10 Not Cancer Driver No 1 hippie 123 379 63 63 0
ACTA1 ACTA1 P68133 Actin, alpha skeletal muscle chr1 Not Cancer Driver No 1 hippie 70 48 14 14 84
ACTA2 ACTA2 P62736 Actin, aortic smooth muscle chr10 Not Cancer Driver No 1 hippie, biogrid 50 39 4 4 17
ACTG1_ENST00000575087 ACTG1 P63261 Actin, cytoplasmic 2 chr17 Not Cancer Driver No 1 hippie 73 42 10 10 16
AGPAT1 AGPAT1 Q99943 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha chr6 Not Cancer Driver No 1 hippie, biogrid 36 38 5 5 0
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 23 20 2 2 0
AJUBA AJUBA Q96IF1 LIM domain-containing protein ajuba chr14 Compendium Yes 1 hippie 45 307 13 13 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 1 hippie 108 158 24 24 4
ANKS1A ANKS1A Q92625 Ankyrin repeat and SAM domain-containing protein 1A chr6 Not Cancer Driver No 1 hippie 120 756 75 75 0
ANPEP ANPEP P15144 Aminopeptidase N chr15 Not Cancer Driver No 1 hippie 175 109 26 26 0
APC APC P25054 Adenomatous polyposis coli protein chr5 Census, Compendium Yes 1 hippie 412 2406 345 345 22
APLP2 APLP2 Q06481 Amyloid beta precursor like protein 2 chr11 Not Cancer Driver No 1 hippie 96 393 48 48 0
ARAF_ENST00000377045 ARAF P10398 Serine/threonine-protein kinase A-Raf chrX Census, Compendium Yes 1 hippie 84 181 32 32 0
ARHGAP11A ARHGAP11A Q6P4F7 Rho GTPase-activating protein 11A chr15 Not Cancer Driver No 1 hippie 127 696 93 93 0
ARHGAP21 ARHGAP21 Q5T5U3 Rho GTPase-activating protein 21 chr10 Not Cancer Driver No 1 hippie 242 1612 204 204 0
ARHGAP32 ARHGAP32 A7KAX9 Rho GTPase-activating protein 32 chr11 Not Cancer Driver No 1 hippie 268 1476 193 193 0
ARHGEF16 ARHGEF16 Q5VV41 Rho guanine nucleotide exchange factor 16 chr1 Not Cancer Driver No 1 hippie 68 297 13 13 0
ARHGEF17 ARHGEF17 Q96PE2 Rho guanine nucleotide exchange factor 17 chr11 Not Cancer Driver No 1 hippie 237 1408 170 170 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 Not Cancer Driver No 1 hippie 170 1141 127 127 0
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 Census Yes 1 hippie 77 511 56 56 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 Not Cancer Driver No 1 hippie 65 451 58 58 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 Census, Compendium Yes 1 hippie 469 225 39 39 41
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 Not Cancer Driver No 2 hippie, biogrid 14 163 14 14 0
BANP_ENST00000286122 BANP Q8N9N5 Protein BANP chr16 Not Cancer Driver No 1 hippie, biogrid 74 311 43 43 0
BAP1 BAP1 Q92560 Ubiquitin carboxyl-terminal hydrolase BAP1 chr3 Census, Compendium Yes 1 hippie 141 418 59 59 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 Census Yes 1 hippie 30 39 2 2 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
BCR BCR P11274 Breakpoint cluster region protein chr22 Census, Compendium Yes 1 hippie 146 603 69 69 0
BLMH BLMH Q13867 Bleomycin hydrolase chr17 Not Cancer Driver No 1 hippie, biogrid 54 15 1 1 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 hippie 50 150 30 30 0
BRAF BRAF P15056 Serine/threonine-protein kinase B-raf chr7 Census, Compendium Yes 1 hippie 791 310 43 43 39
CALML5 CALML5 Q9NZT1 Calmodulin-like protein 5 chr10 Not Cancer Driver No 1 hippie, biogrid 34 98 21 21 0
CAMKK2 CAMKK2 Q96RR4 Calcium/calmodulin-dependent protein kinase kinase 2 chr12 Not Cancer Driver No 1 hippie, biogrid 65 281 35 35 0
CASP14 CASP14 P31944 Caspase-14 chr19 Not Cancer Driver No 1 hippie, biogrid 50 84 13 13 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 Census, Compendium Yes 1 hippie 115 512 56 56 4
CBX4 CBX4 O00257 E3 SUMO-protein ligase CBX4 chr17 Not Cancer Driver No 1 hippie 72 477 63 63 0
CBY1_ENST00000216029 CBY1 Q9Y3M2 Protein chibby homolog 1 chr22 Not Cancer Driver No 1 hippie 13 98 11 11 0
CCAR1 CCAR1 Q8IX12 Cell division cycle and apoptosis regulator protein 1 chr10 Not Cancer Driver No 1 hippie 145 771 76 76 0
CCDC102B CCDC102B Q68D86 Coiled-coil domain-containing protein 102B chr18 Not Cancer Driver No 1 hippie 133 334 89 89 0
CCDC125_ENST00000396499 CCDC125 Q86Z20 Coiled-coil domain-containing protein 125 chr5 Not Cancer Driver No 1 hippie 58 261 23 23 0
CCN1 CCN1 O00622 CCN family member 1 chr1 Not Cancer Driver No 1 hippie 33 12 0 0 0
CCNH CCNH P51946 Cyclin-H chr5 Not Cancer Driver No 1 hippie 40 28 4 4 0
CCR1 CCR1 P32246 C-C chemokine receptor type 1 chr3 Not Cancer Driver No 1 hippie, biogrid 69 14 5 5 0
CDC25A CDC25A P30304 M-phase inducer phosphatase 1 chr3 Not Cancer Driver No 1 hippie 63 313 35 35 0
CDC25B CDC25B P30305 M-phase inducer phosphatase 2 chr20 Not Cancer Driver No 1 hippie 80 328 43 43 0
CDC25C CDC25C P30307 M-phase inducer phosphatase 3 chr5 Not Cancer Driver No 1 hippie 61 224 26 26 0
CDC42BPG CDC42BPG Q6DT37 Serine/threonine-protein kinase MRCK gamma chr11 Not Cancer Driver No 1 hippie 166 736 79 79 0
CDC73 CDC73 Q6P1J9 Parafibromin chr1 Census, Compendium Yes 1 hippie 110 210 39 39 2
CDCA7_ENST00000347703 CDCA7 Q9BWT1 Cell division cycle-associated protein 7 chr2 Not Cancer Driver No 1 hippie, biogrid 68 234 43 43 2
CDH1 CDH1 P12830 Cadherin-1 chr16 Census, Compendium Yes 1 hippie 150 400 82 82 5
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 Not Cancer Driver No 1 hippie 40 1 0 0 0
CDK8 CDK8 P49336 Cyclin-dependent kinase 8 chr13 Not Cancer Driver No 1 hippie 76 152 18 18 7
CDR2L CDR2L Q86X02 Cerebellar degeneration-related protein 2-like chr17 Not Cancer Driver No 1 hippie, biogrid 35 315 20 20 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 hippie 287 145 18 18 151
CGN CGN Q9P2M7 Cingulin chr1 Not Cancer Driver No 1 hippie 152 1179 149 149 0
CHEK1_ENST00000428830 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 Not Cancer Driver No 1 hippie 58 86 16 16 0
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 224 31 31 0
CHST1 CHST1 O43916 Carbohydrate sulfotransferase 1 chr11 Not Cancer Driver No 1 hippie 125 20 8 8 0
CHTOP_ENST00000368694 CHTOP Q9Y3Y2 Chromatin target of PRMT1 protein chr1 Not Cancer Driver No 1 hippie 36 244 34 34 0
COP1 COP1 Q8NHY2 E3 ubiquitin-protein ligase COP1 chr1 Not Cancer Driver No 1 hippie 106 147 11 11 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 36 32 7 7 0
COPS6 COPS6 Q7L5N1 COP9 signalosome complex subunit 6 chr7 Not Cancer Driver No 1 hippie 38 30 6 6 0
CRK CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 1 hippie 30 197 23 23 0
CSNK2A1_ENST00000400217 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 Not Cancer Driver No 1 hippie 71 75 8 8 4
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
CTSD CTSD P07339 Cathepsin D chr11 Not Cancer Driver No 1 hippie, biogrid 57 6 1 1 2
CYTH2_ENST00000641098 CYTH2 Q99418 Cytohesin-2 chr19 Not Cancer Driver No 1 hippie 55 93 12 12 0
DACT1 DACT1 Q9NYF0 Dapper homolog 1 chr14 Not Cancer Driver No 1 hippie 163 598 127 127 1
DCAF7 DCAF7 P61962 DDB1- and CUL4-associated factor 7 chr17 Not Cancer Driver No 1 hippie 48 0 0 0 0
DDX39B_ENST00000458640 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 Not Cancer Driver No 1 hippie 49 34 8 8 0
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 Census Yes 1 hippie 74 225 23 23 0
DEK DEK P35659 Protein DEK chr6 Census Yes 1 hippie 47 297 41 41 0
DHFR DHFR P00374 Dihydrofolate reductase chr5 Not Cancer Driver No 1 hippie, biogrid 16 12 2 2 2
DHX15 DHX15 O43143 ATP-dependent RNA helicase DHX15 chr4 Not Cancer Driver No 1 hippie 110 180 30 30 0
DKC1 DKC1 O60832 H/ACA ribonucleoprotein complex subunit DKC1 chrX Not Cancer Driver No 1 hippie 62 145 29 29 24
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 Not Cancer Driver No 1 hippie, biogrid 53 348 46 46 0
DRG1 DRG1 Q9Y295 Developmentally-regulated GTP-binding protein 1 chr22 Not Cancer Driver No 1 hippie 35 31 0 0 0
DTL DTL Q9NZJ0 Denticleless protein homolog chr1 Not Cancer Driver No 1 hippie 73 331 49 49 0
DTX2 DTX2 Q86UW9 Probable E3 ubiquitin-protein ligase DTX2 chr7 Not Cancer Driver No 1 hippie 84 292 42 42 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 Not Cancer Driver No 1 hippie 135 447 73 73 0
EDC3 EDC3 Q96F86 Enhancer of mRNA-decapping protein 3 chr15 Not Cancer Driver No 1 hippie 43 185 22 22 1
EEA1 EEA1 Q15075 Early endosome antigen 1 chr12 Not Cancer Driver No 1 hippie 151 1168 126 126 0
EEF1A1 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 Not Cancer Driver No 1 hippie 109 100 14 14 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EIF2S1 EIF2S1 P05198 Eukaryotic translation initiation factor 2 subunit 1 chr14 Not Cancer Driver No 1 hippie 35 59 6 6 0
EIF3C EIF3C Q99613 Eukaryotic translation initiation factor 3 subunit C chr16 Not Cancer Driver No 1 hippie 15 391 12 12 0
EIF3G EIF3G O75821 Eukaryotic translation initiation factor 3 subunit G chr19 Not Cancer Driver No 1 hippie 41 233 30 30 0
EIF3H EIF3H O15372 Eukaryotic translation initiation factor 3 subunit H chr8 Not Cancer Driver No 1 hippie 37 109 12 12 0
EIF3I EIF3I Q13347 Eukaryotic translation initiation factor 3 subunit I chr1 Not Cancer Driver No 1 hippie 47 46 6 6 0
EIF4B_ENST00000262056 EIF4B P23588 Eukaryotic translation initiation factor 4B chr12 Not Cancer Driver No 2 hippie, biogrid 94 589 90 90 0
EIF5B EIF5B O60841 Eukaryotic translation initiation factor 5B chr2 Not Cancer Driver No 1 hippie 122 718 71 71 0
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 Not Cancer Driver No 1 hippie 55 297 37 37 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
EXO1_ENST00000348581 EXO1 Q9UQ84 Exonuclease 1 chr1 Not Cancer Driver No 1 hippie 123 472 76 76 0
FAM117B FAM117B Q6P1L5 Protein FAM117B chr2 Not Cancer Driver No 1 hippie 61 547 55 55 0
FAM163A FAM163A Q96GL9 Protein FAM163A chr1 Not Cancer Driver No 1 hippie, biogrid 30 72 14 14 0
FAM189A2 FAM189A2 Q15884 Protein FAM189A2 chr9 Not Cancer Driver No 1 hippie 62 231 29 29 0
FAM53B FAM53B Q14153 Protein FAM53B chr10 Not Cancer Driver No 2 hippie, biogrid 46 254 30 30 0
FAM53C_ENST00000434981 FAM53C Q9NYF3 Protein FAM53C chr5 Not Cancer Driver No 1 hippie 51 296 45 45 0
FAM9B FAM9B Q8IZU0 Protein FAM9B chrX Not Cancer Driver No 1 hippie 40 130 29 29 0
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 176 181 14 14 3
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie 322 230 38 38 0
FHL1_ENST00000345434 FHL1 Q13642 Four and a half LIM domains protein 1 chrX Not Cancer Driver No 1 hippie 56 51 7 7 13
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 Census, Compendium Yes 1 hippie 81 584 75 75 0
FOXO4 FOXO4 P98177 Forkhead box protein O4 chrX Census Yes 1 hippie 75 441 61 61 0
FRMD6 FRMD6 Q96NE9 FERM domain-containing protein 6 chr14 Not Cancer Driver No 1 hippie 116 195 36 36 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 hippie 85 352 65 65 0
G3BP2_ENST00000395719 G3BP2 Q9UN86 Ras GTPase-activating protein-binding protein 2 chr4 Not Cancer Driver No 1 hippie 64 384 53 53 0
G6PD_ENST00000621232 G6PD P11413 Glucose-6-phosphate 1-dehydrogenase chrX Not Cancer Driver No 1 hippie 86 28 3 3 58
GAB2 GAB2 Q9UQC2 GRB2-associated-binding protein 2 chr11 Not Cancer Driver No 1 hippie 85 537 73 73 0
GABARAPL1_ENST00000545887 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 19 10 1 1 0
GAN GAN Q9H2C0 Gigaxonin chr16 Not Cancer Driver No 2 hippie, biogrid 74 33 6 6 19
GOT1 GOT1 P17174 Aspartate aminotransferase, cytoplasmic chr10 Not Cancer Driver No 1 hippie, biogrid 56 35 5 5 0
GPC1 GPC1 P35052 Glypican-1 chr2 Not Cancer Driver No 1 hippie 58 166 14 14 0
GPRIN2_ENST00000374314 GPRIN2 O60269 G protein-regulated inducer of neurite outgrowth 2 chr10 Not Cancer Driver No 1 hippie 145 319 90 90 0
GRB10_ENST00000401949 GRB10 Q13322 Growth factor receptor-bound protein 10 chr7 Not Cancer Driver No 1 hippie 94 220 38 38 0
GRB7_ENST00000394209 GRB7 Q14451 Growth factor receptor-bound protein 7 chr17 Not Cancer Driver No 1 hippie 84 134 27 27 0
GRK4 GRK4 P32298 G protein-coupled receptor kinase 4 chr4 Not Cancer Driver No 1 hippie, biogrid 70 32 2 2 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 Not Cancer Driver No 1 hippie 55 180 8 8 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 2 hippie, biogrid 182 749 132 132 0
HDAC5_ENST00000586802 HDAC5 Q9UQL6 Histone deacetylase 5 chr17 Not Cancer Driver No 2 hippie, biogrid 118 718 73 73 0
HDAC7_ENST00000427332 HDAC7 Q8WUI4 Histone deacetylase 7 chr12 Not Cancer Driver No 2 hippie, biogrid 91 570 50 50 0
HDAC9_ENST00000432645 HDAC9 Q9UKV0 Histone deacetylase 9 chr7 Not Cancer Driver No 1 hippie 286 631 178 178 0
HIVEP3 HIVEP3 Q5T1R4 Transcription factor HIVEP3 chr1 Not Cancer Driver No 1 hippie 369 2194 326 326 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 Not Cancer Driver No 1 hippie 39 206 19 19 0
HNRNPM HNRNPM P52272 Heterogeneous nuclear ribonucleoprotein M chr19 Not Cancer Driver No 1 hippie 108 463 67 67 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 Not Cancer Driver No 1 hippie 77 504 45 45 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 hippie, biogrid 73 282 35 35 0
IGBP1_ENST00000356413 IGBP1 P78318 Immunoglobulin-binding protein 1 chrX Not Cancer Driver No 1 hippie, biogrid 51 193 28 28 0
ILDR2 ILDR2 Q71H61 Immunoglobulin-like domain-containing receptor 2 chr1 Not Cancer Driver No 1 hippie 117 355 49 49 0
IMPDH2 IMPDH2 P12268 Inosine-5'-monophosphate dehydrogenase 2 chr3 Not Cancer Driver No 1 hippie 70 6 1 1 0
INAVA_ENST00000367342 INAVA Q3KP66 Innate immunity activator protein chr1 Not Cancer Driver No 1 hippie 112 553 98 98 1
ING1 ING1 Q9UK53 Inhibitor of growth protein 1 chr13 Compendium Yes 1 hippie 69 209 33 33 3
IPO5_ENST00000490680 IPO5 O00410 Importin-5 chr13 Not Cancer Driver No 1 hippie, biogrid 128 52 3 3 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 Not Cancer Driver No 1 hippie 161 1072 133 133 2
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 Not Cancer Driver No 1 hippie 69 1112 57 57 0
ISCU ISCU Q9H1K1 Iron-sulfur cluster assembly enzyme ISCU, mitochondrial chr12 Not Cancer Driver No 1 hippie 14 24 3 3 0
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 Not Cancer Driver No 1 hippie 12 24 2 2 0
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 Not Cancer Driver No 1 hippie 95 335 42 42 0
ITK ITK Q08881 Tyrosine-protein kinase ITK/TSK chr5 Census Yes 1 hippie, biogrid 139 43 10 10 1
IVL IVL P07476 Involucrin chr1 Not Cancer Driver No 1 hippie, biogrid 115 585 115 115 0
JADE1_ENST00000512960 JADE1 Q6IE81 Protein Jade-1 chr4 Not Cancer Driver No 1 hippie, biogrid 94 409 47 47 0
KANK1_ENST00000382303 KANK1 Q14678 KN motif and ankyrin repeat domain-containing protein 1 chr9 Not Cancer Driver No 1 hippie 183 804 100 100 0
KAT7 KAT7 O95251 Histone acetyltransferase KAT7 chr17 Census Yes 1 hippie, biogrid 97 327 47 47 0
KCNK15 KCNK15 Q9H427 Potassium channel subfamily K member 15 chr20 Not Cancer Driver No 1 hippie 54 32 8 8 0
KCNK3 KCNK3 O14649 Potassium channel subfamily K member 3 chr2 Not Cancer Driver No 1 hippie 54 60 7 7 6
KCNK9 KCNK9 Q9NPC2 Potassium channel subfamily K member 9 chr8 Not Cancer Driver No 1 hippie 139 58 22 22 2
KIAA0408 KIAA0408 Q6ZU52 Uncharacterized protein KIAA0408 chr6 Not Cancer Driver No 1 hippie 112 607 94 94 0
KIAA0930_ENST00000336156 KIAA0930 Q6ICG6 Uncharacterized protein KIAA0930 chr22 Not Cancer Driver No 4 hippie, biogrid 51 148 23 23 0
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 102 559 62 62 0
KIF5B KIF5B P33176 Kinesin-1 heavy chain chr10 Census, Compendium Yes 1 hippie 122 586 67 67 0
KLC1_ENST00000348520 KLC1 Q07866 Kinesin light chain 1 chr14 Not Cancer Driver No 1 hippie 54 292 31 31 0
KLC2_ENST00000394067 KLC2 Q9H0B6 Kinesin light chain 2 chr11 Not Cancer Driver No 1 hippie 75 344 49 49 0
KLHDC2 KLHDC2 Q9Y2U9 Kelch domain-containing protein 2 chr14 Not Cancer Driver No 1 hippie 39 42 2 2 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie 788 7 2 2 27
KRT1 KRT1 P04264 Keratin, type II cytoskeletal 1 chr12 Not Cancer Driver No 1 hippie 133 426 98 98 20
KRT10 KRT10 P13645 Keratin, type I cytoskeletal 10 chr17 Not Cancer Driver No 1 hippie 79 297 38 38 16
KRT18_ENST00000388837 KRT18 P05783 Keratin, type I cytoskeletal 18 chr12 Not Cancer Driver No 1 hippie 57 179 21 21 4
KRT2 KRT2 P35908 Keratin, type II cytoskeletal 2 epidermal chr12 Not Cancer Driver No 1 hippie 122 335 59 59 15
KSR2_ENST00000339824 KSR2 Q6VAB6 Kinase suppressor of Ras 2 chr12 Not Cancer Driver No 1 hippie 231 434 120 120 0
LAD1 LAD1 O00515 Ladinin-1 chr1 Not Cancer Driver No 1 hippie 98 505 98 98 0
LASP1 LASP1 Q14847 LIM and SH3 domain protein 1 chr17 Census Yes 1 hippie 29 198 24 24 0
LMO7_ENST00000357063 LMO7 Q8WWI1 LIM domain only protein 7 chr13 Not Cancer Driver No 1 hippie 267 1102 188 188 0
LNX2 LNX2 Q8N448 Ligand of Numb protein X 2 chr13 Not Cancer Driver No 1 hippie 85 277 35 35 0
LONRF1 LONRF1 Q17RB8 LON peptidase N-terminal domain and RING finger protein 1 chr8 Not Cancer Driver No 1 hippie 64 129 9 9 0
LRRC59 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie 33 122 15 15 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 519 90 17 17 23
LSR_ENST00000361790 LSR Q86X29 Lipolysis-stimulated lipoprotein receptor chr19 Not Cancer Driver No 1 hippie 89 330 42 42 0
LUC7L2 LUC7L2 Q9Y383 Putative RNA-binding protein Luc7-like 2 chr7 Not Cancer Driver No 1 hippie 59 262 45 45 0
MAGEA1 MAGEA1 P43355 Melanoma-associated antigen 1 chrX Not Cancer Driver No 1 hippie 68 71 15 15 0
MAGEB2 MAGEB2 O15479 Melanoma-associated antigen B2 chrX Not Cancer Driver No 1 hippie 98 126 35 35 0
MAGI1 MAGI1 Q96QZ7 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 chr3 Not Cancer Driver No 1 hippie 260 1212 220 220 0
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 Not Cancer Driver No 1 hippie 332 1947 278 278 0
MAP2K3 MAP2K3 P46734 Dual specificity mitogen-activated protein kinase kinase 3 chr17 Not Cancer Driver No 1 hippie 104 75 27 27 0
MAP2K5 MAP2K5 Q13163 Dual specificity mitogen-activated protein kinase kinase 5 chr15 Not Cancer Driver No 1 hippie, biogrid 40 85 10 10 0
MAP3K20 MAP3K20 Q9NYL2 Mitogen-activated protein kinase kinase kinase 20 chr2 Not Cancer Driver No 1 hippie 101 294 41 41 1
MAP3K2_ENST00000344908 MAP3K2 Q9Y2U5 Mitogen-activated protein kinase kinase kinase 2 chr2 Not Cancer Driver No 1 hippie 75 313 47 47 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 Not Cancer Driver No 1 hippie 197 242 29 29 0
MAP3K6 MAP3K6 O95382 Mitogen-activated protein kinase kinase kinase 6 chr1 Not Cancer Driver No 1 hippie, biogrid 108 390 31 31 0
MAPKAP1 MAPKAP1 Q9BPZ7 Target of rapamycin complex 2 subunit MAPKAP1 chr9 Not Cancer Driver No 1 hippie 70 173 25 25 0
MAPRE2 MAPRE2 Q15555 Microtubule-associated protein RP/EB family member 2 chr18 Not Cancer Driver No 1 hippie, biogrid 50 176 28 28 3
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 128 750 126 126 18
MARK1_ENST00000366917 MARK1 Q9P0L2 Serine/threonine-protein kinase MARK1 chr1 Not Cancer Driver No 1 hippie 161 454 108 108 0
MARK2 MARK2 Q7KZI7 Serine/threonine-protein kinase MARK2 chr11 Compendium Yes 1 hippie 124 445 70 70 0
MARK3 MARK3 P27448 MAP/microtubule affinity-regulating kinase 3 chr14 Not Cancer Driver No 1 hippie 92 376 49 49 1
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 104 275 38 38 1
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 56 297 37 37 0
MDM4 MDM4 O15151 Protein Mdm4 chr1 Census, Compendium Yes 1 hippie 57 202 26 26 1
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 Census, Compendium Yes 1 hippie 226 62 15 15 19
MKRN3 MKRN3 Q13064 Probable E3 ubiquitin-protein ligase makorin-3 chr15 Not Cancer Driver No 1 hippie 197 201 99 99 4
MPRIP_ENST00000341712 MPRIP Q6WCQ1 Myosin phosphatase Rho-interacting protein chr17 Not Cancer Driver No 1 hippie 118 735 95 95 0
MST1R MST1R Q04912 Macrophage-stimulating protein receptor chr3 Not Cancer Driver No 1 hippie 178 182 27 27 1
MTMR4 MTMR4 Q9NYA4 Myotubularin-related protein 4 chr17 Not Cancer Driver No 1 hippie 147 474 59 59 0
MYCBP2_ENST00000357337 MYCBP2 O75592 E3 ubiquitin-protein ligase MYCBP2 chr13 Not Cancer Driver No 1 hippie 608 1398 189 189 0
MYH11_ENST00000300036 MYH11 P35749 Myosin-11 chr16 Census, Compendium Yes 1 hippie 353 1180 201 201 2
NEDD4L NEDD4L Q96PU5 E3 ubiquitin-protein ligase NEDD4-like chr18 Not Cancer Driver No 1 hippie 126 463 60 60 4
NEK11 NEK11 Q8NG66 Serine/threonine-protein kinase Nek11 chr3 Not Cancer Driver No 1 hippie, biogrid 91 264 45 45 0
NEK4 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 Not Cancer Driver No 1 hippie, biogrid 78 492 49 49 0
NEK8 NEK8 Q86SG6 Serine/threonine-protein kinase Nek8 chr17 Not Cancer Driver No 1 hippie, biogrid 102 167 40 40 3
NFIA_ENST00000403491 NFIA Q12857 Nuclear factor 1 A-type chr1 Not Cancer Driver No 1 hippie 78 347 55 55 0
NFIB_ENST00000380959 NFIB O00712 Nuclear factor 1 B-type chr9 Census Yes 1 hippie 63 254 36 36 3
NFIC NFIC P08651 Nuclear factor 1 C-type chr19 Not Cancer Driver No 1 hippie 61 327 44 44 0
NINL NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 1 hippie 230 881 150 150 0
NONO NONO Q15233 Non-POU domain-containing octamer-binding protein chrX Census, Compendium Yes 1 hippie 101 349 64 64 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
NSFL1C_ENST00000216879 NSFL1C Q9UNZ2 NSFL1 cofactor p47 chr20 Not Cancer Driver No 1 hippie, biogrid 56 266 39 39 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 Census, Compendium Yes 1 hippie, biogrid 249 57 21 21 0
NUAK2 NUAK2 B4E0Y5 cDNA FLJ56013, highly similar to NUAK family SNF1-like kinase 2 chr1 Not Cancer Driver No 1 hippie, biogrid 91 365 55 55 0
OCRL OCRL Q01968 Inositol polyphosphate 5-phosphatase OCRL chrX Not Cancer Driver No 1 hippie 151 126 24 24 41
OSBPL3 OSBPL3 Q9H4L5 Oxysterol-binding protein-related protein 3 chr7 Not Cancer Driver No 1 hippie 114 324 44 44 0
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 hippie 31 33 2 2 0
OXSR1 OXSR1 O95747 Serine/threonine-protein kinase OSR1 chr3 Not Cancer Driver No 1 hippie, biogrid 69 208 29 29 0
PABPC1 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 Census, Compendium Yes 1 hippie, biogrid 100 317 55 55 0
PACS2_ENST00000325438 PACS2 Q86VP3 Phosphofurin acidic cluster sorting protein 2 chr14 Not Cancer Driver No 1 hippie 122 460 59 59 1
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 Compendium Yes 1 hippie 89 242 49 49 0
PAK4 PAK4 O96013 Serine/threonine-protein kinase PAK 4 chr19 Not Cancer Driver No 1 hippie 58 340 33 33 0
PARD3 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 Not Cancer Driver No 1 hippie 200 1144 170 170 2
PARD3B PARD3B Q8TEW8 Partitioning defective 3 homolog B chr2 Not Cancer Driver No 1 hippie 241 977 203 203 0
PAX9 PAX9 P55771 Paired box protein Pax-9 chr14 Not Cancer Driver No 1 hippie 52 198 32 32 1
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 Not Cancer Driver No 1 hippie 33 121 12 12 0
PDZD11_ENST00000374454 PDZD11 Q5EBL8 PDZ domain-containing protein 11 chrX Not Cancer Driver No 1 hippie 20 46 8 8 0
PEBP1 PEBP1 P30086 Phosphatidylethanolamine-binding protein 1 chr12 Not Cancer Driver No 1 hippie 23 76 13 13 0
PGK1 PGK1 P00558 Phosphoglycerate kinase 1 chrX Not Cancer Driver No 1 hippie, biogrid 61 40 5 5 9
PI4KB_ENST00000368873 PI4KB Q9UBF8 Phosphatidylinositol 4-kinase beta chr1 Not Cancer Driver No 1 hippie 93 311 34 34 0
PIGT PIGT Q969N2 GPI transamidase component PIG-T chr20 Not Cancer Driver No 1 hippie, biogrid 51 36 6 6 1
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PIK3C2B PIK3C2B O00750 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta chr1 Not Cancer Driver No 1 hippie 241 425 71 71 0
PIM3 PIM3 Q86V86 Serine/threonine-protein kinase pim-3 chr22 Not Cancer Driver No 1 hippie, biogrid 24 9 0 0 0
PKN2 PKN2 Q16513 Serine/threonine-protein kinase N2 chr1 Not Cancer Driver No 1 hippie, biogrid 123 415 48 48 0
PKP2 PKP2 Q99959 Plakophilin-2 chr12 Not Cancer Driver No 1 hippie 176 434 98 98 8
PKP3 PKP3 Q9Y446 Plakophilin-3 chr11 Not Cancer Driver No 1 hippie 72 357 22 22 0
PLD6 PLD6 Q8N2A8 Mitochondrial cardiolipin hydrolase chr17 Not Cancer Driver No 3 hippie, biogrid 27 24 6 6 0
PLEC PLEC Q15149 Plectin chr8 Not Cancer Driver No 1 hippie 677 2130 272 272 2
PLEKHF2 PLEKHF2 Q9H8W4 Pleckstrin homology domain-containing family F member 2 chr8 Not Cancer Driver No 1 hippie 32 36 4 4 0
PLK4 PLK4 O00444 Serine/threonine-protein kinase PLK4 chr4 Not Cancer Driver No 1 hippie 102 451 45 45 0
POF1B_ENST00000262753 POF1B Q8WVV4 Protein POF1B chrX Not Cancer Driver No 1 hippie, biogrid 154 391 104 104 1
POLD1_ENST00000440232 POLD1 P28340 DNA polymerase delta catalytic subunit chr19 Census, Compendium Yes 1 hippie 179 214 31 31 2
PPFIBP1 PPFIBP1 Q86W92 Liprin-beta-1 chr12 Census Yes 1 hippie 110 555 57 57 0
PPFIBP2 PPFIBP2 Q8ND30 Liprin-beta-2 chr11 Not Cancer Driver No 1 hippie 95 494 58 58 0
PPIB PPIB P23284 Peptidyl-prolyl cis-trans isomerase B chr15 Not Cancer Driver No 2 hippie, biogrid 28 16 1 1 1
PPIE_ENST00000324379 PPIE Q9UNP9 Peptidyl-prolyl cis-trans isomerase E chr1 Not Cancer Driver No 1 hippie 51 102 17 17 0
PPP1R2 PPP1R2 P41236 Protein phosphatase inhibitor 2 chr3 Not Cancer Driver No 1 hippie, biogrid 19 205 19 19 0
PPP1R3D PPP1R3D O95685 Protein phosphatase 1 regulatory subunit 3D chr20 Not Cancer Driver No 1 hippie 36 94 8 8 0
PPP2R2B_ENST00000394409 PPP2R2B Q00005 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform chr5 Not Cancer Driver No 1 hippie, biogrid 101 76 22 22 0
PRKAR2A PRKAR2A P13861 cAMP-dependent protein kinase type II-alpha regulatory subunit chr3 Not Cancer Driver No 1 hippie 37 149 13 13 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 Not Cancer Driver No 1 hippie 107 170 26 26 0
PRPF8 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie 255 225 26 26 8
PRR5_ENST00000336985 PRR5 P85299 Proline-rich protein 5 chr22 Not Cancer Driver No 1 hippie, biogrid 50 173 22 22 0
PSME3_ENST00000590720 PSME3 P61289 Proteasome activator complex subunit 3 chr17 Not Cancer Driver No 1 hippie, biogrid 20 25 5 5 0
PTOV1_ENST00000599732 PTOV1 Q86YD1 Prostate tumor-overexpressed gene 1 protein chr19 Not Cancer Driver No 1 hippie 56 122 8 8 0
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 Not Cancer Driver No 1 hippie 57 120 14 14 0
PTPN3 PTPN3 P26045 Tyrosine-protein phosphatase non-receptor type 3 chr9 Not Cancer Driver No 1 hippie 139 214 28 28 0
RAB3IP RAB3IP Q96QF0 Rab-3A-interacting protein chr12 Not Cancer Driver No 1 hippie 85 227 33 33 0
RACGAP1_ENST00000454520 RACGAP1 Q9H0H5 Rac GTPase-activating protein 1 chr12 Not Cancer Driver No 1 hippie 74 255 27 27 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 Not Cancer Driver No 1 hippie 34 13 0 0 0
RAE1_ENST00000371242 RAE1 P78406 mRNA export factor RAE1 chr20 Not Cancer Driver No 1 hippie 64 73 11 11 0
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 Census, Compendium Yes 1 hippie 89 169 38 38 22
RALGPS2 RALGPS2 Q86X27 Ras-specific guanine nucleotide-releasing factor RalGPS2 chr1 Not Cancer Driver No 1 hippie 83 183 23 23 0
RANBP3 RANBP3 Q9H6Z4 Ran-binding protein 3 chr19 Not Cancer Driver No 1 hippie, biogrid 71 468 54 54 0
RASSF1 RASSF1 Q9NS23 Ras association domain-containing protein 1 chr3 Not Cancer Driver No 1 hippie 36 79 3 3 0
RBM25 RBM25 P49756 RNA-binding protein 25 chr14 Not Cancer Driver No 1 hippie 124 549 88 88 0
RBM39 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 81 228 39 39 0
REEP3 REEP3 Q6NUK4 Receptor expression-enhancing protein 3 chr10 Not Cancer Driver No 1 hippie 15 94 5 5 0
REEP4 REEP4 Q9H6H4 Receptor expression-enhancing protein 4 chr8 Not Cancer Driver No 1 hippie 27 90 15 15 0
REPS2 REPS2 Q8NFH8 RalBP1-associated Eps domain-containing protein 2 chrX Not Cancer Driver No 1 hippie 94 464 68 68 0
RHPN2 RHPN2 Q8IUC4 Rhophilin-2 chr19 Compendium Yes 1 hippie 111 88 17 17 0
RICTOR_ENST00000357387 RICTOR Q6R327 Rapamycin-insensitive companion of mTOR chr5 Not Cancer Driver No 1 hippie 212 366 50 50 0
RND3_ENST00000263895 RND3 P61587 Rho-related GTP-binding protein RhoE chr2 Not Cancer Driver No 1 hippie 36 70 10 10 0
RNF115 RNF115 Q9Y4L5 E3 ubiquitin-protein ligase RNF115 chr1 Not Cancer Driver No 1 hippie 30 136 14 14 0
RPL10_ENST00000369817 RPL10 P27635 60S ribosomal protein L10 chrX Census, Compendium Yes 1 hippie 46 9 3 3 4
RPL13_ENST00000393099 RPL13 P26373 60S ribosomal protein L13 chr16 Not Cancer Driver No 1 hippie 14 160 11 11 1
RPL17_ENST00000579248 RPL17 P18621 60S ribosomal protein L17 chr18 Not Cancer Driver No 1 hippie 26 97 14 14 0
RPL18 RPL18 Q07020 60S ribosomal protein L18 chr19 Not Cancer Driver No 1 hippie 16 98 6 6 0
RPL23A RPL23A P62750 60S ribosomal protein L23a chr17 Not Cancer Driver No 1 hippie 21 70 13 13 0
RPL24 RPL24 P83731 60S ribosomal protein L24 chr3 Not Cancer Driver No 1 hippie 19 105 14 14 0
RPL26 RPL26 P61254 60S ribosomal protein L26 chr17 Not Cancer Driver No 1 hippie 16 114 13 13 0
RPL27A RPL27A P46776 60S ribosomal protein L27a chr11 Not Cancer Driver No 1 hippie 7 56 2 2 0
RPL34_ENST00000502534 RPL34 P49207 60S ribosomal protein L34 chr4 Not Cancer Driver No 1 hippie 11 31 1 1 0
RPL35 RPL35 P42766 60S ribosomal protein L35 chr9 Not Cancer Driver No 1 hippie 12 65 9 9 0
RPL38_ENST00000439590 RPL38 P63173 60S ribosomal protein L38 chr17 Not Cancer Driver No 1 hippie 2 9 0 0 0
RPL4 RPL4 P36578 60S ribosomal protein L4 chr15 Not Cancer Driver No 1 hippie 49 222 31 31 0
RPL7A RPL7A P62424 60S ribosomal protein L7a chr9 Not Cancer Driver No 1 hippie 27 100 5 5 0
RPL8_ENST00000528957 RPL8 P62917 60S ribosomal protein L8 chr8 Not Cancer Driver No 1 hippie 32 115 17 17 0
RPS11 RPS11 P62280 40S ribosomal protein S11 chr19 Not Cancer Driver No 1 hippie 18 6 0 0 0
RPS13 RPS13 P62277 40S ribosomal protein S13 chr11 Not Cancer Driver No 1 hippie 19 18 5 5 0
RPS15A_ENST00000565420 RPS15A P62244 40S ribosomal protein S15a chr16 Not Cancer Driver No 1 hippie 6 4 0 0 0
RPS16 RPS16 P62249 40S ribosomal protein S16 chr19 Not Cancer Driver No 1 hippie 16 14 1 1 0
RPS18 RPS18 P62269 40S ribosomal protein S18 chr6 Not Cancer Driver No 1 hippie 28 27 8 8 0
RPS19_ENST00000600467 RPS19 P39019 40S ribosomal protein S19 chr19 Not Cancer Driver No 1 hippie 15 61 3 3 23
RPS2 RPS2 P15880 40S ribosomal protein S2 chr16 Not Cancer Driver No 1 hippie 34 85 14 14 0
RPS20_ENST00000521262 RPS20 P60866 40S ribosomal protein S20 chr8 Not Cancer Driver No 1 hippie 18 53 8 8 0
RPS21 RPS21 P63220 40S ribosomal protein S21 chr20 Not Cancer Driver No 1 hippie 8 0 0 0 0
RPS25 RPS25 P62851 40S ribosomal protein S25 chr11 Not Cancer Driver No 1 hippie 16 60 8 8 0
RPS3A RPS3A P61247 40S ribosomal protein S3a chr4 Compendium Yes 1 hippie 21 85 5 5 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 Not Cancer Driver No 1 hippie 22 48 4 4 0
RPS6 RPS6 P62753 40S ribosomal protein S6 chr9 Not Cancer Driver No 1 hippie 38 150 25 25 0
RPS8 RPS8 P62241 40S ribosomal protein S8 chr1 Not Cancer Driver No 1 hippie 23 81 7 7 0
RPS9_ENST00000391752 RPS9 P46781 40S ribosomal protein S9 chr19 Not Cancer Driver No 1 hippie 23 34 5 5 0
RPSA_ENST00000301821 RPSA P08865 40S ribosomal protein SA chr3 Not Cancer Driver No 1 hippie 22 95 6 6 5
RYBP RYBP Q8N488 RING1 and YY1-binding protein chr3 Not Cancer Driver No 1 hippie 37 214 37 37 0
SAMD4A SAMD4A Q9UPU9 Protein Smaug homolog 1 chr14 Not Cancer Driver No 1 hippie 83 473 55 55 0
SAMSN1_ENST00000400566 SAMSN1 Q9NSI8 SAM domain-containing protein SAMSN-1 chr21 Not Cancer Driver No 1 hippie 112 291 85 85 0
SAP18_ENST00000607003 SAP18 O00422 Histone deacetylase complex subunit SAP18 chr13 Not Cancer Driver No 1 hippie 18 99 14 14 0
SASH1 SASH1 O94885 SAM and SH3 domain-containing protein 1 chr6 Not Cancer Driver No 1 hippie 174 1071 153 153 7
SAV1 SAV1 Q9H4B6 Protein salvador homolog 1 chr14 Not Cancer Driver No 1 hippie 42 243 17 17 0
SCEL SCEL O95171 Sciellin chr13 Not Cancer Driver No 1 hippie 137 600 126 126 0
SERBP1 SERBP1 Q8NC51 Plasminogen activator inhibitor 1 RNA-binding protein chr1 Not Cancer Driver No 1 hippie 53 408 53 53 0
SERPINB3 SERPINB3 P29508 Serpin B3 chr18 Not Cancer Driver No 1 hippie, biogrid 142 47 28 28 0
SERPINB5 SERPINB5 P36952 Serpin B5 chr18 Not Cancer Driver No 1 hippie, biogrid 57 50 7 7 0
SETD1A SETD1A O15047 Histone-lysine N-methyltransferase SETD1A chr16 Not Cancer Driver No 1 hippie 223 1327 188 188 5
SFN SFN P31947 14-3-3 protein sigma chr1 Not Cancer Driver No 1 hippie 27 75 9 9 0
SFPQ SFPQ P23246 Splicing factor, proline- and glutamine-rich chr1 Census Yes 1 hippie 59 595 48 48 0
SGF29 SGF29 Q96ES7 SAGA-associated factor 29 chr16 Not Cancer Driver No 1 hippie 31 131 17 17 0
SH2D3A SH2D3A Q9BRG2 SH2 domain-containing protein 3A chr19 Not Cancer Driver No 1 hippie 68 305 40 40 0
SH3BP4_ENST00000392011 SH3BP4 Q9P0V3 SH3 domain-binding protein 4 chr2 Not Cancer Driver No 1 hippie 143 241 43 43 0
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 Not Cancer Driver No 1 hippie 84 397 58 58 0
SHCBP1 SHCBP1 Q8NEM2 SHC SH2 domain-binding protein 1 chr16 Not Cancer Driver No 1 hippie 67 73 8 8 0
SHROOM1 SHROOM1 Q2M3G4 Protein Shroom1 chr5 Not Cancer Driver No 1 hippie 70 712 57 57 0
SHROOM3 SHROOM3 Q8TF72 Protein Shroom3 chr4 Not Cancer Driver No 1 hippie 253 1756 220 220 0
SIK3 SIK3 Q9Y2K2 Serine/threonine-protein kinase SIK3 chr11 Not Cancer Driver No 1 hippie 143 964 107 107 1
SIPA1L1 SIPA1L1 O43166 Signal-induced proliferation-associated 1-like protein 1 chr14 Not Cancer Driver No 1 hippie 321 1175 226 226 0
SIPA1L3 SIPA1L3 O60292 Signal-induced proliferation-associated 1-like protein 3 chr19 Not Cancer Driver No 1 hippie 273 1257 190 190 0
SKP1_ENST00000517625 SKP1 P63208 S-phase kinase-associated protein 1 chr5 Not Cancer Driver No 1 hippie 19 95 17 17 0
SLK SLK Q9H2G2 STE20-like serine/threonine-protein kinase chr10 Not Cancer Driver No 1 hippie, biogrid 134 962 96 96 0
SMTNL2 SMTNL2 Q2TAL5 Smoothelin-like protein 2 chr17 Not Cancer Driver No 2 hippie, biogrid 45 344 33 33 0
SNRPA SNRPA P09012 U1 small nuclear ribonucleoprotein A chr19 Not Cancer Driver No 1 hippie 44 164 24 24 0
SNRPF SNRPF P62306 Small nuclear ribonucleoprotein F chr12 Not Cancer Driver No 1 hippie 4 10 0 0 0
SNRPN_ENST00000577565 SNRPN P63162 Small nuclear ribonucleoprotein-associated protein N chr15 Not Cancer Driver No 1 hippie 92 184 79 79 0
SORBS2_ENST00000284776 SORBS2 O94875 Sorbin and SH3 domain-containing protein 2 chr4 Not Cancer Driver No 1 hippie 172 854 137 137 0
SPIRE1 SPIRE1 Q08AE8 Protein spire homolog 1 chr18 Not Cancer Driver No 1 hippie 78 414 48 48 0
SRRM2 SRRM2 Q9UQ35 Serine/arginine repetitive matrix protein 2 chr16 Not Cancer Driver No 1 hippie 433 2748 431 431 0
SRSF1 SRSF1 Q07955 Serine/arginine-rich splicing factor 1 chr17 Not Cancer Driver No 1 hippie 41 198 34 34 0
SRSF10 SRSF10 O75494 Serine/arginine-rich splicing factor 10 chr1 Not Cancer Driver No 1 hippie 2 192 1 1 0
SRSF2 SRSF2 Q01130 Serine/arginine-rich splicing factor 2 chr17 Census, Compendium Yes 1 hippie 38 219 38 38 0
SRSF4 SRSF4 Q08170 Serine/arginine-rich splicing factor 4 chr1 Not Cancer Driver No 1 hippie 67 409 55 55 0
SRSF8 SRSF8 Q9BRL6 Serine/arginine-rich splicing factor 8 chr11 Not Cancer Driver No 1 hippie 23 282 23 23 0
SUB1_ENST00000515355 SUB1 P53999 Activated RNA polymerase II transcriptional coactivator p15 chr5 Not Cancer Driver No 1 hippie 13 108 6 6 0
SUPT16H SUPT16H Q9Y5B9 FACT complex subunit SPT16 chr14 Not Cancer Driver No 1 hippie 147 301 44 44 0
SYNJ2 SYNJ2 O15056 Synaptojanin-2 chr6 Not Cancer Driver No 1 hippie 189 545 70 70 0
TARDBP TARDBP Q13148 TAR DNA-binding protein 43 chr1 Not Cancer Driver No 1 hippie, biogrid 51 202 15 15 27
TBL3 TBL3 Q12788 Transducin beta-like protein 3 chr16 Not Cancer Driver No 1 hippie 82 48 8 8 0
TEX14 TEX14 Q8IWB6 Inactive serine/threonine-protein kinase TEX14 chr17 Not Cancer Driver No 1 hippie, biogrid 214 872 115 115 0
TJP2_ENST00000377245 TJP2 Q9UDY2 Tight junction protein ZO-2 chr9 Not Cancer Driver No 1 hippie 149 919 113 113 1
TNIK TNIK Q9UKE5 TRAF2 and NCK-interacting protein kinase chr3 Not Cancer Driver No 1 hippie, biogrid 254 781 156 156 0
TNK1 TNK1 Q13470 Non-receptor tyrosine-protein kinase TNK1 chr17 Not Cancer Driver No 1 hippie 51 298 24 24 0
TNS4 TNS4 Q8IZW8 Tensin-4 chr17 Not Cancer Driver No 1 hippie 116 466 78 78 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 Census, Compendium Yes 1 hippie 229 398 143 143 28
TPD52L1_ENST00000534000 TPD52L1 Q16890 Tumor protein D53 chr6 Not Cancer Driver No 1 hippie 46 170 38 38 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie, biogrid 87 430 41 41 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 Not Cancer Driver No 1 hippie 82 87 10 10 3
TRIM62 TRIM62 Q9BVG3 E3 ubiquitin-protein ligase TRIM62 chr1 Not Cancer Driver No 3 hippie, biogrid 58 80 14 14 0
TSC2 TSC2 P49815 Tuberin chr16 Census, Compendium Yes 1 hippie 192 563 50 50 53
TXNL1_ENST00000590954 TXNL1 O43396 Thioredoxin-like protein 1 chr18 Not Cancer Driver No 1 hippie, biogrid 41 89 4 4 0
UBE2R2 UBE2R2 Q712K3 Ubiquitin-conjugating enzyme E2 R2 chr9 Not Cancer Driver No 1 hippie 28 104 15 15 0
USP4 USP4 Q13107 Ubiquitin carboxyl-terminal hydrolase 4 chr3 Not Cancer Driver No 1 hippie 102 286 22 22 0
USP43 USP43 Q70EL4 Ubiquitin carboxyl-terminal hydrolase 43 chr17 Not Cancer Driver No 1 hippie 134 562 56 56 0
USP8 USP8 P40818 Ubiquitin carboxyl-terminal hydrolase 8 chr15 Census, Compendium Yes 1 hippie 122 602 69 69 0
VCL VCL P18206 Vinculin chr10 Not Cancer Driver No 1 hippie 114 673 80 80 2
WDR37_ENST00000263150 WDR37 Q9Y2I8 WD repeat-containing protein 37 chr10 Not Cancer Driver No 1 hippie 63 154 16 16 4
WEE1 WEE1 P30291 Wee1-like protein kinase chr11 Not Cancer Driver No 1 hippie 60 399 27 27 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 2 intact, hippie 51 489 49 49 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 Not Cancer Driver No 2 hippie, biogrid 22 109 4 4 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 hippie 32 41 3 3 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 4 hippie, biogrid 26 77 9 9 2
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 2 hippie, biogrid 15 55 3 3 0
YWHAQ YWHAQ P27348 14-3-3 protein theta chr2 Not Cancer Driver No 4 hippie, biogrid 29 41 6 6 0
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 4 hippie, biogrid 30 81 10 10 0
ZC2HC1C ZC2HC1C Q53FD0 Zinc finger C2HC domain-containing protein 1C chr14 Not Cancer Driver No 1 hippie 39 395 32 32 0
ZC3H18_ENST00000301011 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 1 hippie 139 929 134 134 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 Not Cancer Driver No 1 hippie 43 262 34 34 0
ZFYVE19 ZFYVE19 Q96K21 Abscission/NoCut checkpoint regulator chr15 Not Cancer Driver No 1 hippie 41 361 28 28 0
ZNF638 ZNF638 Q14966 Zinc finger protein 638 chr2 Not Cancer Driver No 1 hippie 243 1667 209 209 0