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SESN2 ,SESN2 ,P58004
  • Uniprot Accession= P58004
  • Ensembl Transcript= ENST00000253063.3
  • Uniprot Name= SESN2
  • Name= Sestrin-2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 14
  • Number of Interaction partner in biogrid: 5
  • Number of Interaction partner in hippie: 29
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ATG13_ENST00000359513 ATG13 O75143 Autophagy-related protein 13 chr11 Not Cancer Driver No 1 intact, hippie 55 205 27 27 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DEPDC5_ENST00000382112 DEPDC5 O75140 GATOR complex protein DEPDC5 chr22 Not Cancer Driver No 1 hippie 226 575 91 91 7
DHX57 DHX57 Q6P158 Putative ATP-dependent RNA helicase DHX57 chr2 Not Cancer Driver No 2 hippie, biogrid 147 294 32 32 0
EDEM1 EDEM1 Q92611 ER degradation-enhancing alpha-mannosidase-like protein 1 chr3 Not Cancer Driver No 1 hippie 54 141 5 5 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
GYPA_ENST00000360771 GYPA P02724 Glycophorin-A chr4 Not Cancer Driver No 1 hippie, biogrid 46 94 31 31 0
KEAP1_ENST00000393623 KEAP1 Q14145 Kelch-like ECH-associated protein 1 chr19 Census, Compendium Yes 1 hippie 237 57 12 12 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 intact, hippie 56 297 37 37 0
MIOS_ENST00000405785 MIOS Q9NXC5 GATOR complex protein MIOS chr7 Not Cancer Driver No 3 intact, hippie 98 72 4 4 0
NPRL2 NPRL2 Q8WTW4 GATOR complex protein NPRL2 chr3 Compendium Yes 1 intact, hippie 37 10 3 3 1
NPRL3_ENST00000611875 NPRL3 Q12980 GATOR complex protein NPRL3 chr16 Not Cancer Driver No 1 hippie 45 158 22 22 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PRDX1_ENST00000319248 PRDX1 Q06830 Peroxiredoxin-1 chr1 Not Cancer Driver No 1 hippie 22 40 5 5 0
RB1CC1 RB1CC1 Q8TDY2 RB1-inducible coiled-coil protein 1 chr8 Not Cancer Driver No 1 intact, hippie 202 578 75 75 0
RBBP5 RBBP5 Q15291 Retinoblastoma-binding protein 5 chr1 Not Cancer Driver No 1 hippie, biogrid 57 218 19 19 0
RBX1 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 Not Cancer Driver No 2 intact, hippie 10 18 1 1 0
RNF186 RNF186 Q9NXI6 E3 ubiquitin-protein ligase RNF186 chr1 Not Cancer Driver No 1 hippie 27 11 3 3 0
SEC13_ENST00000350697 SEC13 P55735 Protein SEC13 homolog chr3 Not Cancer Driver No 3 intact, hippie, biogrid 34 36 6 6 0
SESN2 SESN2 P58004 Sestrin-2 chr1 Not Cancer Driver No 1 intact, hippie 74 147 26 26 0
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 2 intact, hippie 54 267 32 32 30
SZT2_ENST00000634258 SZT2 Q5T011 KICSTOR complex protein SZT2 chr1 Not Cancer Driver No 1 intact, hippie 381 1292 161 161 1
ULK1 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 Not Cancer Driver No 1 intact, hippie 142 588 77 77 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 88 186 16 16 16
WDR24 WDR24 Q96S15 GATOR complex protein WDR24 chr16 Not Cancer Driver No 4 intact, hippie 87 150 17 17 0
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 3 hippie, biogrid 30 35 3 3 0
WDR59 WDR59 Q6PJI9 GATOR complex protein WDR59 chr16 Not Cancer Driver No 2 intact, hippie 119 199 33 33 0