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SDHC ,SDHC ,Q99643
  • Uniprot Accession= Q99643
  • Ensembl Transcript= ENST00000367975.6
  • Uniprot Name= SDHC
  • Name= Succinate dehydrogenase cytochrome b560 subunit, mitochondrial
  • Chromosome= chr1
  • Driver status= Census
  • Number of Interaction partner in intact: 16
  • Number of Interaction partner in biogrid: 26
  • Number of Interaction partner in hippie: 25
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACADVL_ENST00000356839 ACADVL P49748 Very long-chain specific acyl-CoA dehydrogenase, mitochondrial chr17 Not Cancer Driver No 1 intact 50 100 5 5 37
ALB ALB P02768 Albumin chr4 Compendium Yes 1 intact 162 6 0 0 3
ANAPC13 ANAPC13 Q9BS18 Anaphase-promoting complex subunit 13 chr3 Not Cancer Driver No 1 biogrid 5 68 5 5 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie 34 103 14 14 0
ARHGDIA_ENST00000580685 ARHGDIA P52565 Rho GDP-dissociation inhibitor 1 chr17 Not Cancer Driver No 1 hippie 25 50 6 6 0
CARS2 CARS2 Q9HA77 Probable cysteine--tRNA ligase, mitochondrial chr13 Not Cancer Driver No 1 biogrid 51 87 8 8 1
CLPP CLPP Q16740 ATP-dependent Clp protease proteolytic subunit, mitochondrial chr19 Not Cancer Driver No 1 intact, hippie 22 83 9 9 3
CTNNBL1 CTNNBL1 Q8WYA6 Beta-catenin-like protein 1 chr20 Not Cancer Driver No 1 biogrid 72 158 24 24 0
DCTN1 DCTN1 Q14203 Dynactin subunit 1 chr2 Census Yes 1 intact, hippie 172 817 111 111 11
DHODH DHODH Q02127 Dihydroorotate dehydrogenase (quinone), mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 44 96 11 11 10
FBF1_ENST00000586717 FBF1 Q8TES7 Fas-binding factor 1 chr17 Not Cancer Driver No 1 hippie 125 1066 116 116 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
HUS1 HUS1 O60921 Checkpoint protein HUS1 chr7 Not Cancer Driver No 1 biogrid 25 17 2 2 0
IMPDH1_ENST00000626419 IMPDH1 P20839 Inosine-5'-monophosphate dehydrogenase 1 chr7 Not Cancer Driver No 2 hippie, biogrid 75 13 1 1 7
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 Not Cancer Driver No 1 intact, hippie 65 173 21 21 3
LEO1 LEO1 Q8WVC0 RNA polymerase-associated protein LEO1 chr15 Not Cancer Driver No 1 biogrid 74 611 69 69 0
LMO3_ENST00000534946 LMO3 Q8TAP4 LIM domain only protein 3 chr12 Not Cancer Driver No 1 intact, hippie 30 1 0 0 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact 519 90 17 17 23
MAX MAX P61244 Protein max chr14 Census, Compendium Yes 1 biogrid 45 160 45 45 9
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 intact, hippie 56 297 37 37 0
MTCH2 MTCH2 Q9Y6C9 Mitochondrial carrier homolog 2 chr11 Not Cancer Driver No 1 hippie, biogrid 45 11 0 0 0
NCBP1 NCBP1 Q09161 Nuclear cap-binding protein subunit 1 chr9 Not Cancer Driver No 1 biogrid 88 89 8 8 0
NDUFA8 NDUFA8 P51970 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 chr9 Not Cancer Driver No 1 biogrid 25 33 1 1 2
NDUFA9 NDUFA9 Q16795 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial chr12 Not Cancer Driver No 1 biogrid 57 8 0 0 2
NDUFB1_ENST00000605997 NDUFB1 O75438 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 chr14 Not Cancer Driver No 1 biogrid 5 0 0 0 0
NDUFB2_ENST00000247866 NDUFB2 O95178 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial chr7 Not Cancer Driver No 1 biogrid 13 26 3 3 0
NDUFB4 NDUFB4 O95168 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 chr3 Not Cancer Driver No 1 biogrid 13 20 1 1 0
NDUFS2 NDUFS2 O75306 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 58 49 5 5 4
OFD1 OFD1 O75665 Oral-facial-digital syndrome 1 protein chrX Not Cancer Driver No 1 hippie 129 476 58 58 5
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 Not Cancer Driver No 1 biogrid 42 82 11 11 7
PGD PGD P52209 6-phosphogluconate dehydrogenase, decarboxylating chr1 Not Cancer Driver No 1 biogrid 73 19 3 3 0
POC5 POC5 Q8NA72 Centrosomal protein POC5 chr5 Not Cancer Driver No 1 hippie 64 352 46 46 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 Not Cancer Driver No 1 intact, hippie 94 154 22 22 0
PTCD1 PTCD1 O75127 Pentatricopeptide repeat-containing protein 1, mitochondrial chr7 Not Cancer Driver No 1 biogrid 99 224 42 42 0
RBFOX2_ENST00000449924 RBFOX2 O43251 RNA binding protein fox-1 homolog 2 chr22 Compendium Yes 1 hippie 44 173 22 22 0
RPL10_ENST00000369817 RPL10 P27635 60S ribosomal protein L10 chrX Census, Compendium Yes 1 biogrid 46 9 3 3 4
SDHA SDHA P31040 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial chr5 Census Yes 3 intact, hippie, biogrid 115 71 13 13 7
SDHB SDHB P21912 Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial chr1 Census Yes 3 intact, hippie, biogrid 37 17 3 3 23
SDHC SDHC Q99643 Succinate dehydrogenase cytochrome b560 subunit, mitochondrial chr1 Census Yes 1 biogrid 16 0 0 0 0
SDHD SDHD O14521 Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial chr11 Census Yes 3 intact, hippie, biogrid 22 0 0 0 10
SETDB1 SETDB1 Q15047 Histone-lysine N-methyltransferase SETDB1 chr1 Census, Compendium Yes 1 intact, hippie 184 597 77 77 0
SLC25A5 SLC25A5 P05141 ADP/ATP translocase 2 chrX Not Cancer Driver No 1 intact, hippie 41 0 0 0 0
SNAPC1 SNAPC1 Q16533 snRNA-activating protein complex subunit 1 chr14 Not Cancer Driver No 1 biogrid 36 158 16 16 0
UBA2 UBA2 Q9UBT2 SUMO-activating enzyme subunit 2 chr19 Not Cancer Driver No 1 biogrid 84 219 33 33 0
UNK UNK Q9C0B0 RING finger protein unkempt homolog chr17 Not Cancer Driver No 1 hippie 79 511 46 46 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 Not Cancer Driver No 1 intact, hippie 66 140 12 12 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 1 intact, hippie 26 77 9 9 2