Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AAR2_ENST00000320849 | AAR2 | Q9Y312 | Protein AAR2 homolog | chr20 | Not Cancer Driver | No | 1 | hippie | 56 | 28 | 6 | 6 | 0 |
| AARS2 | AARS2 | Q5JTZ9 | Alanine--tRNA ligase, mitochondrial | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 123 | 203 | 25 | 25 | 5 |
| ABCA1 | ABCA1 | O95477 | Phospholipid-transporting ATPase ABCA1 | chr9 | Not Cancer Driver | No | 1 | hippie | 284 | 245 | 40 | 40 | 31 |
| ABCE1 | ABCE1 | P61221 | ATP-binding cassette sub-family E member 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 74 | 36 | 6 | 6 | 0 |
| ACAD11 | ACAD11 | Q709F0 | Acyl-CoA dehydrogenase family member 11 | chr3 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 108 | 33 | 4 | 4 | 0 |
| ACAD9 | ACAD9 | Q9H845 | Complex I assembly factor ACAD9, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 69 | 28 | 5 | 5 | 12 |
| ACADVL_ENST00000356839 | ACADVL | P49748 | Very long-chain specific acyl-CoA dehydrogenase, mitochondrial | chr17 | Not Cancer Driver | No | 1 | intact | 50 | 100 | 5 | 5 | 37 |
| ACAT1 | ACAT1 | P24752 | Acetyl-CoA acetyltransferase, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 32 | 1 | 1 | 10 |
| ACLY_ENST00000590151 | ACLY | P53396 | ATP-citrate synthase | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 120 | 114 | 12 | 12 | 0 |
| ACP6 | ACP6 | Q9NPH0 | Lysophosphatidic acid phosphatase type 6 | chr1 | Not Cancer Driver | No | 1 | hippie | 53 | 40 | 5 | 5 | 0 |
| ACSF3_ENST00000406948 | ACSF3 | Q4G176 | Malonate--CoA ligase ACSF3, mitochondrial | chr16 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 87 | 48 | 11 | 11 | 9 |
| AGL_ENST00000361915 | AGL | P35573 | Glycogen debranching enzyme | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 182 | 143 | 23 | 23 | 1 |
| ATP5F1B | ATP5F1B | P06576 | ATP synthase subunit beta, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie | 60 | 85 | 8 | 8 | 0 |
| ATP6AP2 | ATP6AP2 | O75787 | Renin receptor | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 0 | 0 | 0 | 2 |
| ATXN3 | ATXN3 | P54252 | Ataxin-3 | chr14 | Not Cancer Driver | No | 1 | hippie | 46 | 181 | 24 | 24 | 0 |
| AUH | AUH | Q13825 | Methylglutaconyl-CoA hydratase, mitochondrial | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 29 | 0 | 0 | 1 |
| BAG5_ENST00000299204 | BAG5 | Q9UL15 | BAG family molecular chaperone regulator 5 | chr14 | Not Cancer Driver | No | 1 | hippie | 37 | 63 | 7 | 7 | 0 |
| BCL2L14 | BCL2L14 | Q9BZR8 | Apoptosis facilitator Bcl-2-like protein 14 | chr12 | Not Cancer Driver | No | 1 | hippie | 29 | 40 | 4 | 4 | 0 |
| BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | Census, Compendium | Yes | 1 | hippie | 77 | 98 | 16 | 16 | 0 |
| C1QBP | C1QBP | Q07021 | Complement component 1 Q subcomponent-binding protein, mitochondrial | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 103 | 6 | 6 | 2 |
| CAND1 | CAND1 | Q86VP6 | Cullin-associated NEDD8-dissociated protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 161 | 88 | 7 | 7 | 0 |
| CARTPT | CARTPT | Q16568 | Cocaine- and amphetamine-regulated transcript protein | chr5 | Not Cancer Driver | No | 1 | hippie | 18 | 0 | 0 | 0 | 0 |
| CCNF | CCNF | P41002 | Cyclin-F | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 106 | 221 | 23 | 23 | 3 |
| CHCHD4_ENST00000396914 | CHCHD4 | Q8N4Q1 | Mitochondrial intermembrane space import and assembly protein 40 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 82 | 8 | 8 | 0 |
| CISD1 | CISD1 | Q9NZ45 | CDGSH iron-sulfur domain-containing protein 1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 6 | 18 | 0 | 0 | 0 |
| CIT_ENST00000261833 | CIT | O14578 | Citron Rho-interacting kinase | chr12 | Not Cancer Driver | No | 1 | hippie | 284 | 1017 | 160 | 160 | 3 |
| CLPP | CLPP | Q16740 | ATP-dependent Clp protease proteolytic subunit, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie | 22 | 83 | 9 | 9 | 3 |
| CLPX | CLPX | O76031 | ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial | chr15 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 66 | 195 | 22 | 22 | 1 |
| CLUAP1_ENST00000576634 | CLUAP1 | Q96AJ1 | Clusterin-associated protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 48 | 203 | 22 | 22 | 0 |
| COPS5 | COPS5 | Q92905 | COP9 signalosome complex subunit 5 | chr8 | Not Cancer Driver | No | 1 | hippie | 36 | 32 | 7 | 7 | 0 |
| COQ9 | COQ9 | O75208 | Ubiquinone biosynthesis protein COQ9, mitochondrial | chr16 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 43 | 111 | 13 | 13 | 0 |
| COX4I1 | COX4I1 | P13073 | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 5 | 1 | 1 | 1 |
| COX6B1_ENST00000592141 | COX6B1 | P14854 | Cytochrome c oxidase subunit 6B1 | chr19 | Not Cancer Driver | No | 1 | hippie | 15 | 23 | 6 | 6 | 2 |
| CS | CS | O75390 | Citrate synthase, mitochondrial | chr12 | Not Cancer Driver | No | 3 | hippie, biogrid | 50 | 13 | 2 | 2 | 0 |
| CUL1_ENST00000602748 | CUL1 | Q13616 | Cullin-1 | chr7 | Not Cancer Driver | No | 1 | intact, hippie | 151 | 65 | 9 | 9 | 0 |
| CUL2_ENST00000374748 | CUL2 | Q13617 | Cullin-2 | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 87 | 66 | 3 | 3 | 0 |
| CUL3 | CUL3 | Q13618 | Cullin-3 | chr2 | Census, Compendium | Yes | 1 | intact, hippie | 123 | 167 | 23 | 23 | 3 |
| D2HGDH | D2HGDH | Q8N465 | D-2-hydroxyglutarate dehydrogenase, mitochondrial | chr2 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 61 | 46 | 1 | 1 | 0 |
| DISC1_ENST00000439617 | DISC1 | Q9NRI5 | Disrupted in schizophrenia 1 protein | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 132 | 514 | 82 | 82 | 0 |
| DLAT | DLAT | P10515 | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 294 | 42 | 42 | 0 |
| DLD | DLD | P09622 | Dihydrolipoyl dehydrogenase, mitochondrial | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 17 | 0 | 0 | 10 |
| DNAJA3 | DNAJA3 | Q96EY1 | DnaJ homolog subfamily A member 3, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 152 | 21 | 21 | 0 |
| DNAJC15 | DNAJC15 | Q9Y5T4 | DnaJ homolog subfamily C member 15 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 25 | 4 | 4 | 0 |
| DUSP13_ENST00000472493 | DUSP13 | Q9UII6 | Dual specificity protein phosphatase 13 isoform B | chr10 | Not Cancer Driver | No | 1 | hippie | 45 | 16 | 1 | 1 | 0 |
| EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 13 | 0 | 0 | 0 |
| EMC1 | EMC1 | Q8N766 | ER membrane protein complex subunit 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 107 | 59 | 6 | 6 | 2 |
| ENG | ENG | P17813 | Endoglin | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 60 | 114 | 15 | 15 | 32 |
| FXN | FXN | Q16595 | Frataxin, mitochondrial | chr9 | Not Cancer Driver | No | 1 | hippie | 16 | 73 | 0 | 0 | 8 |
| FZR1 | FZR1 | Q9UM11 | Fizzy-related protein homolog | chr19 | Not Cancer Driver | No | 1 | hippie | 74 | 184 | 30 | 30 | 0 |
| GABARAP | GABARAP | O95166 | Gamma-aminobutyric acid receptor-associated protein | chr17 | Not Cancer Driver | No | 1 | hippie | 9 | 11 | 0 | 0 | 0 |
| GABARAPL1_ENST00000545887 | GABARAPL1 | Q9H0R8 | Gamma-aminobutyric acid receptor-associated protein-like 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 19 | 10 | 1 | 1 | 0 |
| GEM | GEM | P55040 | GTP-binding protein GEM | chr8 | Not Cancer Driver | No | 1 | hippie | 64 | 96 | 22 | 22 | 0 |
| GFM1_ENST00000486715 | GFM1 | Q96RP9 | Elongation factor G, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 74 | 79 | 7 | 7 | 4 |
| GPD2_ENST00000438166 | GPD2 | P43304 | Glycerol-3-phosphate dehydrogenase, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 88 | 67 | 7 | 7 | 0 |
| GPI_ENST00000644934 | GPI | P06744 | Glucose-6-phosphate isomerase | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 77 | 73 | 11 | 11 | 24 |
| GSN | GSN | P06396 | Gelsolin | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 76 | 316 | 28 | 28 | 2 |
| HARS2_ENST00000642231 | HARS2 | P49590 | Histidine--tRNA ligase, mitochondrial | chr5 | Not Cancer Driver | No | 2 | hippie, biogrid | 48 | 34 | 4 | 4 | 2 |
| HDAC4 | HDAC4 | P56524 | Histone deacetylase 4 | chr2 | Not Cancer Driver | No | 1 | hippie | 182 | 749 | 132 | 132 | 0 |
| HINT2 | HINT2 | Q9BX68 | Adenosine 5'-monophosphoramidase HINT2 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 29 | 2 | 2 | 0 |
| HK1_ENST00000359426 | HK1 | P19367 | Hexokinase-1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 127 | 75 | 16 | 16 | 6 |
| HNRNPUL2 | HNRNPUL2 | Q1KMD3 | Heterogeneous nuclear ribonucleoprotein U-like protein 2 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 71 | 418 | 35 | 35 | 0 |
| HSCB | HSCB | Q8IWL3 | Iron-sulfur cluster co-chaperone protein HscB | chr22 | Not Cancer Driver | No | 3 | intact, hippie | 36 | 25 | 6 | 6 | 0 |
| HSPA9 | HSPA9 | P38646 | Stress-70 protein, mitochondrial | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 67 | 283 | 26 | 26 | 2 |
| HSPD1 | HSPD1 | P10809 | 60 kDa heat shock protein, mitochondrial | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 61 | 82 | 6 | 6 | 2 |
| IKBKE | IKBKE | Q14164 | Inhibitor of nuclear factor kappa-B kinase subunit epsilon | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 108 | 76 | 13 | 13 | 0 |
| ILVBL | ILVBL | A1L0T0 | 2-hydroxyacyl-CoA lyase 2 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 86 | 30 | 1 | 1 | 0 |
| IMMP2L_ENST00000452895 | IMMP2L | Q96T52 | Mitochondrial inner membrane protease subunit 2 | chr7 | Not Cancer Driver | No | 1 | hippie | 36 | 29 | 7 | 7 | 0 |
| IQGAP1 | IQGAP1 | P46940 | Ras GTPase-activating-like protein IQGAP1 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 183 | 351 | 35 | 35 | 0 |
| ISCU | ISCU | Q9H1K1 | Iron-sulfur cluster assembly enzyme ISCU, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie | 14 | 24 | 3 | 3 | 0 |
| ITGA4 | ITGA4 | P13612 | Integrin alpha-4 | chr2 | Not Cancer Driver | No | 1 | hippie | 254 | 97 | 27 | 27 | 0 |
| IWS1 | IWS1 | Q96ST2 | Protein IWS1 homolog | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 80 | 737 | 72 | 72 | 0 |
| JUN | JUN | P05412 | Transcription factor Jun | chr1 | Census | Yes | 1 | hippie | 35 | 281 | 25 | 25 | 0 |
| LAMTOR2 | LAMTOR2 | Q9Y2Q5 | Ragulator complex protein LAMTOR2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 12 | 0 | 0 | 0 | 0 |
| LARS2_ENST00000645846 | LARS2 | Q15031 | Leucine--tRNA ligase, mitochondrial | chr3 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 74 | 80 | 8 | 8 | 3 |
| LDHA_ENST00000422447 | LDHA | P00338 | L-lactate dehydrogenase A chain | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 9 | 0 | 0 | 0 |
| LRPPRC | LRPPRC | P42704 | Leucine-rich PPR motif-containing protein, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 131 | 18 | 2 | 2 | 1 |
| LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 519 | 90 | 17 | 17 | 23 |
| MAP2K7_ENST00000397979 | MAP2K7 | O14733 | Dual specificity mitogen-activated protein kinase kinase 7 | chr19 | Compendium | Yes | 1 | hippie, biogrid | 89 | 144 | 20 | 20 | 0 |
| MAP4K2 | MAP4K2 | Q12851 | Mitogen-activated protein kinase kinase kinase kinase 2 | chr11 | Not Cancer Driver | No | 1 | hippie | 78 | 243 | 23 | 23 | 0 |
| MAT2A | MAT2A | P31153 | S-adenosylmethionine synthase isoform type-2 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 31 | 4 | 4 | 0 |
| MCC_ENST00000302475 | MCC | P23508 | Colorectal mutant cancer protein | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 136 | 589 | 92 | 92 | 0 |
| MCU | MCU | Q8NE86 | Calcium uniporter protein, mitochondrial | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 41 | 13 | 0 | 0 | 0 |
| MDH2 | MDH2 | P40926 | Malate dehydrogenase, mitochondrial | chr7 | Not Cancer Driver | No | 2 | hippie, biogrid | 39 | 8 | 1 | 1 | 3 |
| METTL17_ENST00000339374 | METTL17 | Q9H7H0 | Methyltransferase-like protein 17, mitochondrial | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 95 | 16 | 16 | 0 |
| MGST3 | MGST3 | O14880 | Microsomal glutathione S-transferase 3 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 17 | 0 | 0 | 0 | 0 |
| MMADHC_ENST00000303319 | MMADHC | Q9H3L0 | Cobalamin trafficking protein CblD | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 65 | 8 | 8 | 3 |
| MRPL20 | MRPL20 | Q9BYC9 | 39S ribosomal protein L20, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 0 | 0 | 0 | 0 |
| MRPL40 | MRPL40 | Q9NQ50 | 39S ribosomal protein L40, mitochondrial | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 104 | 9 | 9 | 0 |
| MRPL48 | MRPL48 | Q96GC5 | 39S ribosomal protein L48, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 15 | 1 | 1 | 0 |
| MRPS10 | MRPS10 | P82664 | 28S ribosomal protein S10, mitochondrial | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 22 | 3 | 3 | 0 |
| MRPS5 | MRPS5 | P82675 | 28S ribosomal protein S5, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 157 | 20 | 20 | 0 |
| MSRA | MSRA | Q9UJ68 | Mitochondrial peptide methionine sulfoxide reductase | chr8 | Not Cancer Driver | No | 1 | hippie | 39 | 81 | 14 | 14 | 0 |
| MTCH2 | MTCH2 | Q9Y6C9 | Mitochondrial carrier homolog 2 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 11 | 0 | 0 | 0 |
| MTMR14 | MTMR14 | Q8NCE2 | Myotubularin-related protein 14 | chr3 | Not Cancer Driver | No | 1 | hippie | 58 | 150 | 8 | 8 | 2 |
| MYLK | MYLK | Q15746 | Myosin light chain kinase, smooth muscle | chr3 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 343 | 957 | 184 | 184 | 3 |
| NCAPD3 | NCAPD3 | P42695 | Condensin-2 complex subunit D3 | chr11 | Not Cancer Driver | No | 1 | hippie | 193 | 304 | 42 | 42 | 1 |
| NDUFA10 | NDUFA10 | O95299 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 19 | 0 | 0 | 1 |
| NDUFA12 | NDUFA12 | Q9UI09 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 31 | 6 | 6 | 0 |
| NDUFA2 | NDUFA2 | O43678 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 0 | 0 | 0 | 0 |
| NDUFA4 | NDUFA4 | O00483 | Cytochrome c oxidase subunit NDUFA4 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 4 | 0 | 0 | 0 |
| NDUFA6_ENST00000602404 | NDUFA6 | P56556 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 14 | 2 | 2 | 1 |
| NDUFA9 | NDUFA9 | Q16795 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 8 | 0 | 0 | 2 |
| NDUFAB1_ENST00000007516 | NDUFAB1 | O14561 | Acyl carrier protein, mitochondrial | chr16 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 23 | 0 | 0 | 0 | 0 |
| NDUFB11_ENST00000377811 | NDUFB11 | Q9NX14 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 51 | 6 | 6 | 1 |
| NDUFB6 | NDUFB6 | O95139 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 20 | 3 | 3 | 0 |
| NDUFB9 | NDUFB9 | Q9Y6M9 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 | chr8 | Not Cancer Driver | No | 2 | hippie, biogrid | 23 | 34 | 5 | 5 | 1 |
| NDUFS1_ENST00000449699 | NDUFS1 | P28331 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | chr2 | Not Cancer Driver | No | 2 | hippie, biogrid | 81 | 40 | 3 | 3 | 2 |
| NDUFS4 | NDUFS4 | O43181 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 92 | 17 | 17 | 1 |
| NDUFS8 | NDUFS8 | O00217 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 37 | 2 | 2 | 3 |
| NDUFV1 | NDUFV1 | P49821 | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 66 | 57 | 9 | 9 | 3 |
| NDUFV2 | NDUFV2 | P19404 | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial | chr18 | Not Cancer Driver | No | 2 | hippie, biogrid | 40 | 69 | 15 | 15 | 0 |
| NIPSNAP3A | NIPSNAP3A | Q9UFN0 | Protein NipSnap homolog 3A | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 15 | 4 | 4 | 0 |
| OCIAD1 | OCIAD1 | Q9NX40 | OCIA domain-containing protein 1 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 169 | 25 | 25 | 0 |
| OTUB1_ENST00000428192 | OTUB1 | Q96FW1 | Ubiquitin thioesterase OTUB1 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 31 | 33 | 2 | 2 | 0 |
| OXA1L_ENST00000604262 | OXA1L | Q15070 | Mitochondrial inner membrane protein OXA1L | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 81 | 9 | 9 | 0 |
| P2RY6_ENST00000540342 | P2RY6 | Q15077 | P2Y purinoceptor 6 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 50 | 10 | 5 | 5 | 0 |
| PAPLN_ENST00000644200 | PAPLN | O95428 | Papilin | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 175 | 572 | 74 | 74 | 0 |
| PCLAF | PCLAF | Q15004 | PCNA-associated factor | chr15 | Not Cancer Driver | No | 1 | hippie | 20 | 111 | 20 | 20 | 0 |
| PDHA1_ENST00000422285 | PDHA1 | P08559 | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | chrX | Not Cancer Driver | No | 2 | hippie, biogrid | 70 | 43 | 6 | 6 | 20 |
| PDHA2 | PDHA2 | P29803 | Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 163 | 41 | 17 | 17 | 0 |
| PDK1_ENST00000282077 | PDK1 | Q15118 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 52 | 50 | 10 | 10 | 0 |
| PDPR | PDPR | Q8NCN5 | Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial | chr16 | Compendium | Yes | 1 | intact, hippie, biogrid | 142 | 35 | 4 | 4 | 0 |
| PIGR | PIGR | P01833 | Polymeric immunoglobulin receptor | chr1 | Not Cancer Driver | No | 1 | hippie | 126 | 177 | 37 | 37 | 0 |
| PIGS | PIGS | Q96S52 | GPI transamidase component PIG-S | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 59 | 32 | 4 | 4 | 2 |
| PIH1D1 | PIH1D1 | Q9NWS0 | PIH1 domain-containing protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 30 | 157 | 13 | 13 | 0 |
| PIK3R5 | PIK3R5 | Q8WYR1 | Phosphoinositide 3-kinase regulatory subunit 5 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 143 | 316 | 55 | 55 | 1 |
| POLG_ENST00000442287 | POLG | P54098 | DNA polymerase subunit gamma-1 | chr15 | Census | Yes | 2 | hippie, biogrid | 139 | 421 | 42 | 42 | 73 |
| PRDX6 | PRDX6 | P30041 | Peroxiredoxin-6 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 13 | 4 | 4 | 0 |
| PREPL_ENST00000409272 | PREPL | Q4J6C6 | Prolyl endopeptidase-like | chr2 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 107 | 91 | 20 | 20 | 0 |
| PTPDC1_ENST00000375360 | PTPDC1 | A2A3K4 | Protein tyrosine phosphatase domain-containing protein 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 85 | 301 | 26 | 26 | 0 |
| RAB7A | RAB7A | P51149 | Ras-related protein Rab-7a | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 11 | 0 | 0 | 4 |
| RAB8A | RAB8A | P61006 | Ras-related protein Rab-8A | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 26 | 3 | 3 | 0 |
| RBM14 | RBM14 | Q96PK6 | RNA-binding protein 14 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 99 | 350 | 59 | 59 | 0 |
| RECQL4 | RECQL4 | O94761 | ATP-dependent DNA helicase Q4 | chr8 | Census, Compendium | Yes | 1 | hippie | 138 | 608 | 71 | 71 | 1 |
| RIN3 | RIN3 | Q8TB24 | Ras and Rab interactor 3 | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 137 | 417 | 61 | 61 | 0 |
| RSAD1 | RSAD1 | Q9HA92 | Radical S-adenosyl methionine domain-containing protein 1, mitochondrial | chr17 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 68 | 88 | 13 | 13 | 0 |
| RTP4 | RTP4 | Q96DX8 | Receptor-transporting protein 4 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 40 | 27 | 5 | 5 | 0 |
| S100A9 | S100A9 | P06702 | Protein S100-A9 | chr1 | Not Cancer Driver | No | 1 | hippie | 18 | 76 | 7 | 7 | 0 |
| SDHA | SDHA | P31040 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | chr5 | Census | Yes | 7 | intact, hippie, biogrid | 115 | 71 | 13 | 13 | 7 |
| SDHAF1 | SDHAF1 | A6NFY7 | Succinate dehydrogenase assembly factor 1, mitochondrial | chr19 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 1 | 108 | 1 | 1 | 3 |
| SDHAF3 | SDHAF3 | Q9NRP4 | Succinate dehydrogenase assembly factor 3, mitochondrial | chr7 | Not Cancer Driver | No | 2 | intact, hippie | 18 | 65 | 5 | 5 | 0 |
| SDHC | SDHC | Q99643 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | chr1 | Census | Yes | 3 | intact, hippie, biogrid | 16 | 0 | 0 | 0 | 0 |
| SDHD | SDHD | O14521 | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial | chr11 | Census | Yes | 1 | hippie, biogrid | 22 | 0 | 0 | 0 | 10 |
| SIRT3 | SIRT3 | Q9NTG7 | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | chr11 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 33 | 60 | 2 | 2 | 0 |
| SLC25A22_ENST00000628067 | SLC25A22 | Q9H936 | Mitochondrial glutamate carrier 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 22 | 2 | 2 | 1 |
| SLC25A3 | SLC25A3 | Q00325 | Phosphate carrier protein, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 32 | 4 | 4 | 1 |
| SLC25A5 | SLC25A5 | P05141 | ADP/ATP translocase 2 | chrX | Not Cancer Driver | No | 1 | intact, hippie | 41 | 0 | 0 | 0 | 0 |
| SPNS1 | SPNS1 | Q9H2V7 | Protein spinster homolog 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 69 | 61 | 5 | 5 | 0 |
| SPRY2 | SPRY2 | O43597 | Protein sprouty homolog 2 | chr13 | Not Cancer Driver | No | 1 | intact, hippie | 46 | 169 | 29 | 29 | 1 |
| SSBP1_ENST00000484178 | SSBP1 | Q04837 | Single-stranded DNA-binding protein, mitochondrial | chr7 | Not Cancer Driver | No | 2 | hippie, biogrid | 27 | 0 | 0 | 0 | 6 |
| SUCLA2 | SUCLA2 | Q9P2R7 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 46 | 6 | 6 | 3 |
| SUCLG1 | SUCLG1 | P53597 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 57 | 8 | 8 | 3 |
| TBRG4_ENST00000494076 | TBRG4 | Q969Z0 | FAST kinase domain-containing protein 4 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 74 | 60 | 2 | 2 | 0 |
| TEX101_ENST00000598265 | TEX101 | Q9BY14 | Testis-expressed protein 101 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 45 | 2 | 0 | 0 | 0 |
| TIMM50_ENST00000607714 | TIMM50 | Q3ZCQ8 | Mitochondrial import inner membrane translocase subunit TIM50 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 75 | 7 | 7 | 0 |
| TMED2 | TMED2 | Q15363 | Transmembrane emp24 domain-containing protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 25 | 4 | 4 | 0 |
| TMEM70 | TMEM70 | Q9BUB7 | Transmembrane protein 70, mitochondrial | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 24 | 4 | 4 | 1 |
| TNIP2 | TNIP2 | Q8NFZ5 | TNFAIP3-interacting protein 2 | chr4 | Not Cancer Driver | No | 1 | hippie | 43 | 316 | 36 | 36 | 0 |
| TOMM40_ENST00000405636 | TOMM40 | O96008 | Mitochondrial import receptor subunit TOM40 homolog | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 98 | 1 | 1 | 0 |
| TOMM7 | TOMM7 | Q9P0U1 | Mitochondrial import receptor subunit TOM7 homolog | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 7 | 0 | 0 | 0 | 0 |
| TOP3A | TOP3A | Q13472 | DNA topoisomerase 3-alpha | chr17 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 103 | 293 | 31 | 31 | 2 |
| TP53BP1_ENST00000263801 | TP53BP1 | Q12888 | TP53-binding protein 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 227 | 1632 | 190 | 190 | 0 |
| TRIM28 | TRIM28 | Q13263 | Transcription intermediary factor 1-beta | chr19 | Not Cancer Driver | No | 1 | hippie | 87 | 430 | 41 | 41 | 0 |
| TRUB2 | TRUB2 | O95900 | Pseudouridylate synthase TRUB2, mitochondrial | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 73 | 7 | 7 | 0 |
| TSFM_ENST00000454289 | TSFM | P43897 | Elongation factor Ts, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 74 | 7 | 7 | 2 |
| TUFM | TUFM | P49411 | Elongation factor Tu, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 50 | 3 | 3 | 1 |
| TULP3_ENST00000448120 | TULP3 | O75386 | Tubby-related protein 3 | chr12 | Not Cancer Driver | No | 1 | hippie | 66 | 218 | 29 | 29 | 0 |
| TXLNA_ENST00000373610 | TXLNA | P40222 | Alpha-taxilin | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 68 | 481 | 59 | 59 | 0 |
| UAP1 | UAP1 | Q16222 | UDP-N-acetylhexosamine pyrophosphorylase | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 78 | 7 | 7 | 0 |
| UAP1L1 | UAP1L1 | Q3KQV9 | UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 120 | 5 | 5 | 0 |
| UBXN10 | UBXN10 | Q96LJ8 | UBX domain-containing protein 10 | chr1 | Not Cancer Driver | No | 1 | hippie | 51 | 254 | 48 | 48 | 0 |
| UQCRB_ENST00000287022 | UQCRB | P14927 | Cytochrome b-c1 complex subunit 7 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 2 | 1 | 1 | 0 |
| UQCRC2 | UQCRC2 | P22695 | Cytochrome b-c1 complex subunit 2, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 48 | 13 | 13 | 1 |
| UQCRFS1 | UQCRFS1 | P47985 | Cytochrome b-c1 complex subunit Rieske, mitochondrial | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 47 | 4 | 4 | 1 |
| VCAM1 | VCAM1 | P19320 | Vascular cell adhesion protein 1 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 188 | 110 | 28 | 28 | 0 |
| VDAC3_ENST00000022615 | VDAC3 | Q9Y277 | Voltage-dependent anion-selective channel protein 3 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 24 | 0 | 0 | 0 | 0 |
| VIRMA | VIRMA | Q69YN4 | Protein virilizer homolog | chr8 | Not Cancer Driver | No | 1 | hippie | 211 | 631 | 93 | 93 | 0 |
| WWOX | WWOX | Q9NZC7 | WW domain-containing oxidoreductase | chr16 | Not Cancer Driver | No | 1 | hippie | 79 | 108 | 9 | 9 | 3 |
| XRN1 | XRN1 | Q8IZH2 | 5'-3' exoribonuclease 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 213 | 577 | 65 | 65 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|