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SDHB ,SDHB ,P21912
  • Uniprot Accession= P21912
  • Ensembl Transcript= ENST00000375499.7
  • Uniprot Name= SDHB
  • Name= Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
  • Chromosome= chr1
  • Driver status= Census
  • Number of Interaction partner in intact: 39
  • Number of Interaction partner in biogrid: 108
  • Number of Interaction partner in hippie: 178
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 56 28 6 6 0
AARS2 AARS2 Q5JTZ9 Alanine--tRNA ligase, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 123 203 25 25 5
ABCA1 ABCA1 O95477 Phospholipid-transporting ATPase ABCA1 chr9 Not Cancer Driver No 1 hippie 284 245 40 40 31
ABCE1 ABCE1 P61221 ATP-binding cassette sub-family E member 1 chr4 Not Cancer Driver No 1 hippie 74 36 6 6 0
ACAD11 ACAD11 Q709F0 Acyl-CoA dehydrogenase family member 11 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 108 33 4 4 0
ACAD9 ACAD9 Q9H845 Complex I assembly factor ACAD9, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 69 28 5 5 12
ACADVL_ENST00000356839 ACADVL P49748 Very long-chain specific acyl-CoA dehydrogenase, mitochondrial chr17 Not Cancer Driver No 1 intact 50 100 5 5 37
ACAT1 ACAT1 P24752 Acetyl-CoA acetyltransferase, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 45 32 1 1 10
ACLY_ENST00000590151 ACLY P53396 ATP-citrate synthase chr17 Not Cancer Driver No 1 hippie, biogrid 120 114 12 12 0
ACP6 ACP6 Q9NPH0 Lysophosphatidic acid phosphatase type 6 chr1 Not Cancer Driver No 1 hippie 53 40 5 5 0
ACSF3_ENST00000406948 ACSF3 Q4G176 Malonate--CoA ligase ACSF3, mitochondrial chr16 Not Cancer Driver No 2 intact, hippie, biogrid 87 48 11 11 9
AGL_ENST00000361915 AGL P35573 Glycogen debranching enzyme chr1 Not Cancer Driver No 1 hippie, biogrid 182 143 23 23 1
ATP5F1B ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 Not Cancer Driver No 1 hippie 60 85 8 8 0
ATP6AP2 ATP6AP2 O75787 Renin receptor chrX Not Cancer Driver No 1 hippie, biogrid 56 0 0 0 2
ATXN3 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 hippie 46 181 24 24 0
AUH AUH Q13825 Methylglutaconyl-CoA hydratase, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 34 29 0 0 1
BAG5_ENST00000299204 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 Not Cancer Driver No 1 hippie 37 63 7 7 0
BCL2L14 BCL2L14 Q9BZR8 Apoptosis facilitator Bcl-2-like protein 14 chr12 Not Cancer Driver No 1 hippie 29 40 4 4 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 14 103 6 6 2
CAND1 CAND1 Q86VP6 Cullin-associated NEDD8-dissociated protein 1 chr12 Not Cancer Driver No 1 hippie 161 88 7 7 0
CARTPT CARTPT Q16568 Cocaine- and amphetamine-regulated transcript protein chr5 Not Cancer Driver No 1 hippie 18 0 0 0 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 106 221 23 23 3
CHCHD4_ENST00000396914 CHCHD4 Q8N4Q1 Mitochondrial intermembrane space import and assembly protein 40 chr3 Not Cancer Driver No 1 hippie, biogrid 18 82 8 8 0
CISD1 CISD1 Q9NZ45 CDGSH iron-sulfur domain-containing protein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 6 18 0 0 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CLPP CLPP Q16740 ATP-dependent Clp protease proteolytic subunit, mitochondrial chr19 Not Cancer Driver No 1 hippie 22 83 9 9 3
CLPX CLPX O76031 ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial chr15 Not Cancer Driver No 1 intact, hippie, biogrid 66 195 22 22 1
CLUAP1_ENST00000576634 CLUAP1 Q96AJ1 Clusterin-associated protein 1 chr16 Not Cancer Driver No 1 hippie 48 203 22 22 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 36 32 7 7 0
COQ9 COQ9 O75208 Ubiquinone biosynthesis protein COQ9, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie, biogrid 43 111 13 13 0
COX4I1 COX4I1 P13073 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 17 5 1 1 1
COX6B1_ENST00000592141 COX6B1 P14854 Cytochrome c oxidase subunit 6B1 chr19 Not Cancer Driver No 1 hippie 15 23 6 6 2
CS CS O75390 Citrate synthase, mitochondrial chr12 Not Cancer Driver No 3 hippie, biogrid 50 13 2 2 0
CUL1_ENST00000602748 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 1 intact, hippie 151 65 9 9 0
CUL2_ENST00000374748 CUL2 Q13617 Cullin-2 chr10 Not Cancer Driver No 1 intact, hippie 87 66 3 3 0
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact, hippie 123 167 23 23 3
D2HGDH D2HGDH Q8N465 D-2-hydroxyglutarate dehydrogenase, mitochondrial chr2 Not Cancer Driver No 2 intact, hippie, biogrid 61 46 1 1 0
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 intact, hippie 132 514 82 82 0
DLAT DLAT P10515 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 63 294 42 42 0
DLD DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 67 17 0 0 10
DNAJA3 DNAJA3 Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 50 152 21 21 0
DNAJC15 DNAJC15 Q9Y5T4 DnaJ homolog subfamily C member 15 chr13 Not Cancer Driver No 1 hippie, biogrid 19 25 4 4 0
DUSP13_ENST00000472493 DUSP13 Q9UII6 Dual specificity protein phosphatase 13 isoform B chr10 Not Cancer Driver No 1 hippie 45 16 1 1 0
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EMC1 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 1 hippie 107 59 6 6 2
ENG ENG P17813 Endoglin chr9 Not Cancer Driver No 1 intact, hippie 60 114 15 15 32
FXN FXN Q16595 Frataxin, mitochondrial chr9 Not Cancer Driver No 1 hippie 16 73 0 0 8
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 74 184 30 30 0
GABARAP GABARAP O95166 Gamma-aminobutyric acid receptor-associated protein chr17 Not Cancer Driver No 1 hippie 9 11 0 0 0
GABARAPL1_ENST00000545887 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 19 10 1 1 0
GEM GEM P55040 GTP-binding protein GEM chr8 Not Cancer Driver No 1 hippie 64 96 22 22 0
GFM1_ENST00000486715 GFM1 Q96RP9 Elongation factor G, mitochondrial chr3 Not Cancer Driver No 1 hippie, biogrid 74 79 7 7 4
GPD2_ENST00000438166 GPD2 P43304 Glycerol-3-phosphate dehydrogenase, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 88 67 7 7 0
GPI_ENST00000644934 GPI P06744 Glucose-6-phosphate isomerase chr19 Not Cancer Driver No 1 hippie, biogrid 77 73 11 11 24
GSN GSN P06396 Gelsolin chr9 Not Cancer Driver No 1 hippie, biogrid 76 316 28 28 2
HARS2_ENST00000642231 HARS2 P49590 Histidine--tRNA ligase, mitochondrial chr5 Not Cancer Driver No 2 hippie, biogrid 48 34 4 4 2
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 1 hippie 182 749 132 132 0
HINT2 HINT2 Q9BX68 Adenosine 5'-monophosphoramidase HINT2 chr9 Not Cancer Driver No 1 hippie, biogrid 10 29 2 2 0
HK1_ENST00000359426 HK1 P19367 Hexokinase-1 chr10 Not Cancer Driver No 1 hippie, biogrid 127 75 16 16 6
HNRNPUL2 HNRNPUL2 Q1KMD3 Heterogeneous nuclear ribonucleoprotein U-like protein 2 chr11 Not Cancer Driver No 1 hippie, biogrid 71 418 35 35 0
HSCB HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 3 intact, hippie 36 25 6 6 0
HSPA9 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 1 intact, hippie 67 283 26 26 2
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 61 82 6 6 2
IKBKE IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 Not Cancer Driver No 1 intact, hippie 108 76 13 13 0
ILVBL ILVBL A1L0T0 2-hydroxyacyl-CoA lyase 2 chr19 Not Cancer Driver No 1 hippie, biogrid 86 30 1 1 0
IMMP2L_ENST00000452895 IMMP2L Q96T52 Mitochondrial inner membrane protease subunit 2 chr7 Not Cancer Driver No 1 hippie 36 29 7 7 0
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 Not Cancer Driver No 1 hippie, biogrid 183 351 35 35 0
ISCU ISCU Q9H1K1 Iron-sulfur cluster assembly enzyme ISCU, mitochondrial chr12 Not Cancer Driver No 1 hippie 14 24 3 3 0
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 Not Cancer Driver No 1 hippie 254 97 27 27 0
IWS1 IWS1 Q96ST2 Protein IWS1 homolog chr2 Not Cancer Driver No 1 hippie, biogrid 80 737 72 72 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
LAMTOR2 LAMTOR2 Q9Y2Q5 Ragulator complex protein LAMTOR2 chr1 Not Cancer Driver No 1 hippie, biogrid 12 0 0 0 0
LARS2_ENST00000645846 LARS2 Q15031 Leucine--tRNA ligase, mitochondrial chr3 Not Cancer Driver No 1 intact, hippie, biogrid 74 80 8 8 3
LDHA_ENST00000422447 LDHA P00338 L-lactate dehydrogenase A chain chr11 Not Cancer Driver No 1 hippie, biogrid 40 9 0 0 0
LRPPRC LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 131 18 2 2 1
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 Compendium Yes 1 hippie, biogrid 89 144 20 20 0
MAP4K2 MAP4K2 Q12851 Mitogen-activated protein kinase kinase kinase kinase 2 chr11 Not Cancer Driver No 1 hippie 78 243 23 23 0
MAT2A MAT2A P31153 S-adenosylmethionine synthase isoform type-2 chr2 Not Cancer Driver No 1 hippie, biogrid 36 31 4 4 0
MCC_ENST00000302475 MCC P23508 Colorectal mutant cancer protein chr5 Not Cancer Driver No 1 intact, hippie 136 589 92 92 0
MCU MCU Q8NE86 Calcium uniporter protein, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 41 13 0 0 0
MDH2 MDH2 P40926 Malate dehydrogenase, mitochondrial chr7 Not Cancer Driver No 2 hippie, biogrid 39 8 1 1 3
METTL17_ENST00000339374 METTL17 Q9H7H0 Methyltransferase-like protein 17, mitochondrial chr14 Not Cancer Driver No 1 hippie, biogrid 62 95 16 16 0
MGST3 MGST3 O14880 Microsomal glutathione S-transferase 3 chr1 Not Cancer Driver No 1 intact, hippie 17 0 0 0 0
MMADHC_ENST00000303319 MMADHC Q9H3L0 Cobalamin trafficking protein CblD chr2 Not Cancer Driver No 1 hippie, biogrid 31 65 8 8 3
MRPL20 MRPL20 Q9BYC9 39S ribosomal protein L20, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 20 0 0 0 0
MRPL40 MRPL40 Q9NQ50 39S ribosomal protein L40, mitochondrial chr22 Not Cancer Driver No 1 hippie, biogrid 20 104 9 9 0
MRPL48 MRPL48 Q96GC5 39S ribosomal protein L48, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 16 15 1 1 0
MRPS10 MRPS10 P82664 28S ribosomal protein S10, mitochondrial chr6 Not Cancer Driver No 1 hippie, biogrid 19 22 3 3 0
MRPS5 MRPS5 P82675 28S ribosomal protein S5, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 52 157 20 20 0
MSRA MSRA Q9UJ68 Mitochondrial peptide methionine sulfoxide reductase chr8 Not Cancer Driver No 1 hippie 39 81 14 14 0
MTCH2 MTCH2 Q9Y6C9 Mitochondrial carrier homolog 2 chr11 Not Cancer Driver No 1 hippie, biogrid 45 11 0 0 0
MTMR14 MTMR14 Q8NCE2 Myotubularin-related protein 14 chr3 Not Cancer Driver No 1 hippie 58 150 8 8 2
MYLK MYLK Q15746 Myosin light chain kinase, smooth muscle chr3 Not Cancer Driver No 1 intact, hippie, biogrid 343 957 184 184 3
NCAPD3 NCAPD3 P42695 Condensin-2 complex subunit D3 chr11 Not Cancer Driver No 1 hippie 193 304 42 42 1
NDUFA10 NDUFA10 O95299 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 48 19 0 0 1
NDUFA12 NDUFA12 Q9UI09 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 chr12 Not Cancer Driver No 1 hippie, biogrid 18 31 6 6 0
NDUFA2 NDUFA2 O43678 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 chr5 Not Cancer Driver No 1 hippie, biogrid 10 0 0 0 0
NDUFA4 NDUFA4 O00483 Cytochrome c oxidase subunit NDUFA4 chr7 Not Cancer Driver No 1 hippie, biogrid 14 4 0 0 0
NDUFA6_ENST00000602404 NDUFA6 P56556 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 chr22 Not Cancer Driver No 1 hippie, biogrid 10 14 2 2 1
NDUFA9 NDUFA9 Q16795 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 57 8 0 0 2
NDUFAB1_ENST00000007516 NDUFAB1 O14561 Acyl carrier protein, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie, biogrid 23 0 0 0 0
NDUFB11_ENST00000377811 NDUFB11 Q9NX14 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 26 51 6 6 1
NDUFB6 NDUFB6 O95139 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 chr9 Not Cancer Driver No 1 hippie, biogrid 24 20 3 3 0
NDUFB9 NDUFB9 Q9Y6M9 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 chr8 Not Cancer Driver No 2 hippie, biogrid 23 34 5 5 1
NDUFS1_ENST00000449699 NDUFS1 P28331 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial chr2 Not Cancer Driver No 2 hippie, biogrid 81 40 3 3 2
NDUFS4 NDUFS4 O43181 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial chr5 Not Cancer Driver No 1 hippie, biogrid 26 92 17 17 1
NDUFS8 NDUFS8 O00217 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 27 37 2 2 3
NDUFV1 NDUFV1 P49821 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial chr11 Not Cancer Driver No 1 hippie, biogrid 66 57 9 9 3
NDUFV2 NDUFV2 P19404 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial chr18 Not Cancer Driver No 2 hippie, biogrid 40 69 15 15 0
NIPSNAP3A NIPSNAP3A Q9UFN0 Protein NipSnap homolog 3A chr9 Not Cancer Driver No 1 hippie, biogrid 26 15 4 4 0
OCIAD1 OCIAD1 Q9NX40 OCIA domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie, biogrid 37 169 25 25 0
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 intact, hippie 31 33 2 2 0
OXA1L_ENST00000604262 OXA1L Q15070 Mitochondrial inner membrane protein OXA1L chr14 Not Cancer Driver No 1 hippie, biogrid 36 81 9 9 0
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 Not Cancer Driver No 1 intact, hippie 50 10 5 5 0
PAPLN_ENST00000644200 PAPLN O95428 Papilin chr14 Not Cancer Driver No 1 hippie, biogrid 175 572 74 74 0
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 2 hippie, biogrid 70 43 6 6 20
PDHA2 PDHA2 P29803 Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial chr4 Not Cancer Driver No 1 hippie, biogrid 163 41 17 17 0
PDK1_ENST00000282077 PDK1 Q15118 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial chr2 Not Cancer Driver No 1 intact, hippie 52 50 10 10 0
PDPR PDPR Q8NCN5 Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial chr16 Compendium Yes 1 intact, hippie, biogrid 142 35 4 4 0
PIGR PIGR P01833 Polymeric immunoglobulin receptor chr1 Not Cancer Driver No 1 hippie 126 177 37 37 0
PIGS PIGS Q96S52 GPI transamidase component PIG-S chr17 Not Cancer Driver No 1 hippie, biogrid 59 32 4 4 2
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PIK3R5 PIK3R5 Q8WYR1 Phosphoinositide 3-kinase regulatory subunit 5 chr17 Not Cancer Driver No 1 intact, hippie 143 316 55 55 1
POLG_ENST00000442287 POLG P54098 DNA polymerase subunit gamma-1 chr15 Census Yes 2 hippie, biogrid 139 421 42 42 73
PRDX6 PRDX6 P30041 Peroxiredoxin-6 chr1 Not Cancer Driver No 1 hippie, biogrid 46 13 4 4 0
PREPL_ENST00000409272 PREPL Q4J6C6 Prolyl endopeptidase-like chr2 Not Cancer Driver No 2 intact, hippie, biogrid 107 91 20 20 0
PTPDC1_ENST00000375360 PTPDC1 A2A3K4 Protein tyrosine phosphatase domain-containing protein 1 chr9 Not Cancer Driver No 1 hippie 85 301 26 26 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 hippie, biogrid 27 11 0 0 4
RAB8A RAB8A P61006 Ras-related protein Rab-8A chr19 Not Cancer Driver No 1 hippie, biogrid 37 26 3 3 0
RBM14 RBM14 Q96PK6 RNA-binding protein 14 chr11 Not Cancer Driver No 1 hippie, biogrid 99 350 59 59 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RIN3 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 intact, hippie 137 417 61 61 0
RSAD1 RSAD1 Q9HA92 Radical S-adenosyl methionine domain-containing protein 1, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie, biogrid 68 88 13 13 0
RTP4 RTP4 Q96DX8 Receptor-transporting protein 4 chr3 Not Cancer Driver No 1 hippie, biogrid 40 27 5 5 0
S100A9 S100A9 P06702 Protein S100-A9 chr1 Not Cancer Driver No 1 hippie 18 76 7 7 0
SDHA SDHA P31040 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial chr5 Census Yes 7 intact, hippie, biogrid 115 71 13 13 7
SDHAF1 SDHAF1 A6NFY7 Succinate dehydrogenase assembly factor 1, mitochondrial chr19 Not Cancer Driver No 3 intact, hippie, biogrid 1 108 1 1 3
SDHAF3 SDHAF3 Q9NRP4 Succinate dehydrogenase assembly factor 3, mitochondrial chr7 Not Cancer Driver No 2 intact, hippie 18 65 5 5 0
SDHC SDHC Q99643 Succinate dehydrogenase cytochrome b560 subunit, mitochondrial chr1 Census Yes 3 intact, hippie, biogrid 16 0 0 0 0
SDHD SDHD O14521 Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial chr11 Census Yes 1 hippie, biogrid 22 0 0 0 10
SIRT3 SIRT3 Q9NTG7 NAD-dependent protein deacetylase sirtuin-3, mitochondrial chr11 Not Cancer Driver No 1 intact, hippie, biogrid 33 60 2 2 0
SLC25A22_ENST00000628067 SLC25A22 Q9H936 Mitochondrial glutamate carrier 1 chr11 Not Cancer Driver No 1 hippie, biogrid 34 22 2 2 1
SLC25A3 SLC25A3 Q00325 Phosphate carrier protein, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 49 32 4 4 1
SLC25A5 SLC25A5 P05141 ADP/ATP translocase 2 chrX Not Cancer Driver No 1 intact, hippie 41 0 0 0 0
SPNS1 SPNS1 Q9H2V7 Protein spinster homolog 1 chr16 Not Cancer Driver No 1 hippie 69 61 5 5 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 Not Cancer Driver No 1 intact, hippie 46 169 29 29 1
SSBP1_ENST00000484178 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 Not Cancer Driver No 2 hippie, biogrid 27 0 0 0 6
SUCLA2 SUCLA2 Q9P2R7 Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial chr13 Not Cancer Driver No 1 hippie, biogrid 51 46 6 6 3
SUCLG1 SUCLG1 P53597 Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 48 57 8 8 3
TBRG4_ENST00000494076 TBRG4 Q969Z0 FAST kinase domain-containing protein 4 chr7 Not Cancer Driver No 1 hippie, biogrid 74 60 2 2 0
TEX101_ENST00000598265 TEX101 Q9BY14 Testis-expressed protein 101 chr19 Not Cancer Driver No 1 intact, hippie 45 2 0 0 0
TIMM50_ENST00000607714 TIMM50 Q3ZCQ8 Mitochondrial import inner membrane translocase subunit TIM50 chr19 Not Cancer Driver No 1 hippie, biogrid 39 75 7 7 0
TMED2 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 24 25 4 4 0
TMEM70 TMEM70 Q9BUB7 Transmembrane protein 70, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 26 24 4 4 1
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 43 316 36 36 0
TOMM40_ENST00000405636 TOMM40 O96008 Mitochondrial import receptor subunit TOM40 homolog chr19 Not Cancer Driver No 1 hippie, biogrid 17 98 1 1 0
TOMM7 TOMM7 Q9P0U1 Mitochondrial import receptor subunit TOM7 homolog chr7 Not Cancer Driver No 1 hippie, biogrid 7 0 0 0 0
TOP3A TOP3A Q13472 DNA topoisomerase 3-alpha chr17 Not Cancer Driver No 2 intact, hippie, biogrid 103 293 31 31 2
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 Not Cancer Driver No 1 hippie 227 1632 190 190 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
TRUB2 TRUB2 O95900 Pseudouridylate synthase TRUB2, mitochondrial chr9 Not Cancer Driver No 1 hippie, biogrid 37 73 7 7 0
TSFM_ENST00000454289 TSFM P43897 Elongation factor Ts, mitochondrial chr12 Not Cancer Driver No 1 hippie, biogrid 37 74 7 7 2
TUFM TUFM P49411 Elongation factor Tu, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 51 50 3 3 1
TULP3_ENST00000448120 TULP3 O75386 Tubby-related protein 3 chr12 Not Cancer Driver No 1 hippie 66 218 29 29 0
TXLNA_ENST00000373610 TXLNA P40222 Alpha-taxilin chr1 Not Cancer Driver No 1 hippie, biogrid 68 481 59 59 0
UAP1 UAP1 Q16222 UDP-N-acetylhexosamine pyrophosphorylase chr1 Not Cancer Driver No 1 hippie, biogrid 67 78 7 7 0
UAP1L1 UAP1L1 Q3KQV9 UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 36 120 5 5 0
UBXN10 UBXN10 Q96LJ8 UBX domain-containing protein 10 chr1 Not Cancer Driver No 1 hippie 51 254 48 48 0
UQCRB_ENST00000287022 UQCRB P14927 Cytochrome b-c1 complex subunit 7 chr8 Not Cancer Driver No 1 hippie, biogrid 28 2 1 1 0
UQCRC2 UQCRC2 P22695 Cytochrome b-c1 complex subunit 2, mitochondrial chr16 Not Cancer Driver No 1 hippie, biogrid 53 48 13 13 1
UQCRFS1 UQCRFS1 P47985 Cytochrome b-c1 complex subunit Rieske, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 43 47 4 4 1
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 intact, hippie 188 110 28 28 0
VDAC3_ENST00000022615 VDAC3 Q9Y277 Voltage-dependent anion-selective channel protein 3 chr8 Not Cancer Driver No 1 hippie, biogrid 24 0 0 0 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 hippie 79 108 9 9 3
XRN1 XRN1 Q8IZH2 5'-3' exoribonuclease 1 chr3 Not Cancer Driver No 1 hippie 213 577 65 65 0