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SDF4 ,SDF4 ,Q9BRK5
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 71
  • Number of Interaction partner in hippie: 136
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCB7_ENST00000373394 ABCB7 O75027 Iron-sulfur clusters transporter ABCB7, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 117 79 14 14 4
ABCE1 ABCE1 P61221 ATP-binding cassette sub-family E member 1 chr4 Not Cancer Driver No 1 hippie 74 36 6 6 0
ACAD11 ACAD11 Q709F0 Acyl-CoA dehydrogenase family member 11 chr3 Not Cancer Driver No 3 hippie, biogrid 108 33 4 4 0
ACP5_ENST00000433365 ACP5 P13686 Tartrate-resistant acid phosphatase type 5 chr19 Not Cancer Driver No 1 hippie 51 31 6 6 8
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 Not Cancer Driver No 1 hippie, biogrid 107 537 67 67 0
ANG ANG P03950 Angiogenin chr14 Not Cancer Driver No 1 hippie 19 36 2 2 14
ANXA7 ANXA7 P20073 Annexin A7 chr10 Not Cancer Driver No 1 hippie 68 215 37 37 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ARAF_ENST00000377045 ARAF P10398 Serine/threonine-protein kinase A-Raf chrX Census, Compendium Yes 1 hippie 84 181 32 32 0
ARFGEF2 ARFGEF2 Q9Y6D5 Brefeldin A-inhibited guanine nucleotide-exchange protein 2 chr20 Not Cancer Driver No 2 hippie, biogrid 254 358 63 63 0
ARL8B ARL8B Q9NVJ2 ADP-ribosylation factor-like protein 8B chr3 Not Cancer Driver No 3 hippie, biogrid 28 0 0 0 0
ARMC6 ARMC6 Q6NXE6 Armadillo repeat-containing protein 6 chr19 Not Cancer Driver No 1 hippie 65 77 5 5 0
ATP2B2 ATP2B2 Q01814 Plasma membrane calcium-transporting ATPase 2 chr3 Not Cancer Driver No 3 hippie, biogrid 248 360 82 82 0
BCL2L14 BCL2L14 Q9BZR8 Apoptosis facilitator Bcl-2-like protein 14 chr12 Not Cancer Driver No 1 hippie 29 40 4 4 0
BRCA2_ENST00000544455 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 Census, Compendium Yes 1 hippie, biogrid 457 1542 225 225 46
BRD1_ENST00000216267 BRD1 O95696 Bromodomain-containing protein 1 chr22 Not Cancer Driver No 1 hippie 171 425 68 68 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BRD8 BRD8 Q9H0E9 Bromodomain-containing protein 8 chr5 Not Cancer Driver No 1 hippie 189 934 147 147 0
CALR3 CALR3 Q96L12 Calreticulin-3 chr19 Not Cancer Driver No 2 hippie, biogrid 60 101 16 16 0
CALU_ENST00000249364 CALU O43852 Calumenin chr7 Not Cancer Driver No 1 hippie, biogrid 34 130 12 12 0
CASP6 CASP6 P55212 Caspase-6 chr4 Not Cancer Driver No 1 hippie 28 24 4 4 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 Census, Compendium Yes 1 hippie 48 121 30 30 0
CHST11 CHST11 Q9NPF2 Carbohydrate sulfotransferase 11 chr12 Census Yes 3 hippie, biogrid 69 45 11 11 0
CHST12 CHST12 Q9NRB3 Carbohydrate sulfotransferase 12 chr7 Not Cancer Driver No 3 hippie, biogrid 75 84 15 15 0
CHSY1 CHSY1 Q86X52 Chondroitin sulfate synthase 1 chr15 Not Cancer Driver No 1 hippie, biogrid 95 137 10 10 1
CLK2 CLK2 P49760 Dual specificity protein kinase CLK2 chr1 Not Cancer Driver No 1 hippie, biogrid 104 151 37 37 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 Not Cancer Driver No 1 hippie, biogrid 69 156 27 27 0
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 hippie 123 167 23 23 3
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DNAJB12_ENST00000444643 DNAJB12 Q9NXW2 DnaJ homolog subfamily B member 12 chr10 Not Cancer Driver No 1 hippie, biogrid 43 227 20 20 0
DUSP21 DUSP21 Q9H596 Dual specificity protein phosphatase 21 chrX Not Cancer Driver No 1 hippie 49 0 0 0 0
ERF ERF P50548 ETS domain-containing transcription factor ERF chr19 Not Cancer Driver No 3 hippie, biogrid 74 398 54 54 3
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FAM20C FAM20C Q8IXL6 Extracellular serine/threonine protein kinase FAM20C chr7 Not Cancer Driver No 1 hippie 33 188 3 3 9
FAM83H FAM83H Q6ZRV2 Protein FAM83H chr8 Not Cancer Driver No 1 hippie, biogrid 151 893 95 95 1
FHL2_ENST00000408995 FHL2 Q14192 Four and a half LIM domains protein 2 chr2 Not Cancer Driver No 3 hippie, biogrid 30 0 0 0 0
FKBP10 FKBP10 Q96AY3 Peptidyl-prolyl cis-trans isomerase FKBP10 chr17 Not Cancer Driver No 1 hippie, biogrid 60 134 8 8 3
FOXF1 FOXF1 Q12946 Forkhead box protein F1 chr16 Not Cancer Driver No 2 hippie, biogrid 56 194 20 20 20
FOXF2 FOXF2 Q12947 Forkhead box protein F2 chr6 Not Cancer Driver No 3 hippie, biogrid 44 277 10 10 0
GALNT11_ENST00000430044 GALNT11 Q8NCW6 Polypeptide N-acetylgalactosaminyltransferase 11 chr7 Not Cancer Driver No 3 hippie, biogrid 73 91 18 18 0
GPRIN1 GPRIN1 Q7Z2K8 G protein-regulated inducer of neurite outgrowth 1 chr5 Not Cancer Driver No 3 hippie, biogrid 116 999 115 115 0
GRPEL1 GRPEL1 Q9HAV7 GrpE protein homolog 1, mitochondrial chr4 Not Cancer Driver No 1 hippie, biogrid 22 88 7 7 0
GTPBP6 GTPBP6 O43824 Putative GTP-binding protein 6 chrX Not Cancer Driver No 3 hippie, biogrid 32 117 0 0 0
HOOK3 HOOK3 Q86VS8 Protein Hook homolog 3 chr8 Census Yes 1 hippie, biogrid 79 493 55 55 0
HSCB HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 1 hippie 36 25 6 6 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 Not Cancer Driver No 1 hippie 73 282 35 35 0
IFT122_ENST00000348417 IFT122 Q9HBG6 Intraflagellar transport protein 122 homolog chr3 Not Cancer Driver No 1 hippie, biogrid 157 54 5 5 5
IFT27 IFT27 Q9BW83 Intraflagellar transport protein 27 homolog chr22 Not Cancer Driver No 1 hippie 14 0 0 0 1
ILK_ENST00000299421 ILK Q13418 Integrin-linked protein kinase chr11 Not Cancer Driver No 2 hippie, biogrid 45 71 9 9 0
IQGAP2 IQGAP2 Q13576 Ras GTPase-activating-like protein IQGAP2 chr5 Not Cancer Driver No 3 hippie, biogrid 237 255 50 50 0
IRAK1 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX Compendium Yes 1 hippie, biogrid 71 337 39 39 0
ITFG1 ITFG1 Q8TB96 T-cell immunomodulatory protein chr16 Not Cancer Driver No 1 hippie 70 18 3 3 0
ITGB3BP_ENST00000271002 ITGB3BP Q13352 Centromere protein R chr1 Not Cancer Driver No 1 hippie 19 122 14 14 0
KIAA1671_ENST00000406486 KIAA1671 Q9BY89 Uncharacterized protein KIAA1671 chr22 Not Cancer Driver No 3 hippie, biogrid 14 1759 14 14 0
KIF2C KIF2C Q99661 Kinesin-like protein KIF2C chr1 Not Cancer Driver No 1 hippie 110 337 63 63 0
KIRREL1 KIRREL1 Q96J84 Kin of IRRE-like protein 1 chr1 Not Cancer Driver No 1 hippie 141 273 57 57 1
KSR1_ENST00000644974 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 Not Cancer Driver No 2 hippie, biogrid 114 404 58 58 0
LAMP2_ENST00000200639 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX Not Cancer Driver No 1 hippie 43 55 7 7 1
LATS2 LATS2 Q9NRM7 Serine/threonine-protein kinase LATS2 chr13 Census, Compendium Yes 1 hippie, biogrid 178 687 116 116 0
LRFN1 LRFN1 Q9P244 Leucine-rich repeat and fibronectin type III domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 96 278 37 37 0
LRRC59 LRRC59 Q96AG4 Leucine-rich repeat-containing protein 59 chr17 Not Cancer Driver No 1 hippie, biogrid 33 122 15 15 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 Not Cancer Driver No 1 hippie 22 0 0 0 1
MADD MADD Q8WXG6 MAP kinase-activating death domain protein chr11 Not Cancer Driver No 1 hippie, biogrid 207 723 81 81 4
MAPRE2 MAPRE2 Q15555 Microtubule-associated protein RP/EB family member 2 chr18 Not Cancer Driver No 1 hippie, biogrid 50 176 28 28 3
MGARP MGARP Q8TDB4 Protein MGARP chr4 Not Cancer Driver No 1 hippie, biogrid 25 207 22 22 0
MME_ENST00000492661 MME P08473 Neprilysin chr3 Not Cancer Driver No 1 hippie 189 40 17 17 4
MOK MOK Q9UQ07 MAPK/MAK/MRK overlapping kinase chr14 Not Cancer Driver No 1 hippie 44 135 13 13 0
MPC2 MPC2 O95563 Mitochondrial pyruvate carrier 2 chr1 Not Cancer Driver No 1 hippie, biogrid 13 0 0 0 0
MTFR1L_ENST00000374303 MTFR1L Q9H019 Mitochondrial fission regulator 1-like chr1 Not Cancer Driver No 3 hippie, biogrid 25 108 10 10 0
MTO1_ENST00000370300 MTO1 Q9Y2Z2 Protein MTO1 homolog, mitochondrial chr6 Not Cancer Driver No 3 hippie, biogrid 70 61 2 2 1
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYO9B_ENST00000594824 MYO9B Q13459 Unconventional myosin-IXb chr19 Not Cancer Driver No 3 hippie, biogrid 226 827 80 80 0
NCAPD3 NCAPD3 P42695 Condensin-2 complex subunit D3 chr11 Not Cancer Driver No 1 hippie, biogrid 193 304 42 42 1
NCAPH2_ENST00000420993 NCAPH2 Q6IBW4 Condensin-2 complex subunit H2 chr22 Not Cancer Driver No 1 hippie, biogrid 67 335 39 39 0
NDST2 NDST2 P52849 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 chr10 Not Cancer Driver No 2 hippie, biogrid 95 60 7 7 0
NEK4 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 Not Cancer Driver No 3 hippie, biogrid 78 492 49 49 0
NPW NPW Q8N729 Neuropeptide W chr16 Not Cancer Driver No 1 hippie, biogrid 14 76 5 5 0
NR1I2_ENST00000393716 NR1I2 O75469 Nuclear receptor subfamily 1 group I member 2 chr3 Not Cancer Driver No 1 hippie 60 81 8 8 0
NRBP2 NRBP2 Q9NSY0 Nuclear receptor-binding protein 2 chr8 Not Cancer Driver No 1 hippie, biogrid 30 110 5 5 0
NUCB2_ENST00000622082 NUCB2 P80303 Nucleobindin-2 chr11 Not Cancer Driver No 1 hippie, biogrid 49 265 40 40 0
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 Not Cancer Driver No 1 hippie 50 10 5 5 0
PDIA4 PDIA4 P13667 Protein disulfide-isomerase A4 chr7 Not Cancer Driver No 1 hippie, biogrid 81 147 22 22 0
PLD2 PLD2 O14939 Phospholipase D2 chr17 Not Cancer Driver No 1 hippie, biogrid 107 97 8 8 0
PLK4 PLK4 O00444 Serine/threonine-protein kinase PLK4 chr4 Not Cancer Driver No 1 hippie 102 451 45 45 0
POU5F1 POU5F1 Q01860 POU domain, class 5, transcription factor 1 chr6 Census Yes 1 hippie 36 186 12 12 0
PPEF2 PPEF2 O14830 Serine/threonine-protein phosphatase with EF-hands 2 chr4 Not Cancer Driver No 1 hippie 144 130 29 29 0
PPOX PPOX P50336 Protoporphyrinogen oxidase chr1 Not Cancer Driver No 1 hippie, biogrid 48 34 6 6 56
PRPF40A PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 hippie 83 694 57 57 0
PTPN18 PTPN18 Q99952 Tyrosine-protein phosphatase non-receptor type 18 chr2 Not Cancer Driver No 1 hippie 51 138 8 8 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 Not Cancer Driver No 1 hippie 141 364 62 62 4
PTPRO PTPRO Q16827 Receptor-type tyrosine-protein phosphatase O chr12 Not Cancer Driver No 1 hippie 204 137 34 34 0
RAP1B_ENST00000393436 RAP1B P61224 Ras-related protein Rap-1b chr12 Not Cancer Driver No 1 hippie 26 14 3 3 0
RBX1 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 Not Cancer Driver No 1 hippie 10 18 1 1 0
RCC1_ENST00000373833 RCC1 P18754 Regulator of chromosome condensation chr1 Not Cancer Driver No 1 hippie 54 143 15 15 0
RCN2_ENST00000394885 RCN2 Q14257 Reticulocalbin-2 chr15 Not Cancer Driver No 1 hippie, biogrid 35 125 11 11 0
RGPD5_ENST00000393283 RGPD5 Q99666-2 Isoform 2 of RANBP2-like and GRIP domain-containing protein 5/6 chr2 Not Cancer Driver No 1 biogrid 1 141 1 1 0
RICTOR_ENST00000357387 RICTOR Q6R327 Rapamycin-insensitive companion of mTOR chr5 Not Cancer Driver No 3 hippie, biogrid 212 366 50 50 0
RIPK4_ENST00000352483 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 hippie 119 232 34 34 3
RPA2_ENST00000373912 RPA2 P15927 Replication protein A 32 kDa subunit chr1 Not Cancer Driver No 1 hippie 28 114 16 16 0
SEC61B SEC61B P60468 Protein transport protein Sec61 subunit beta chr9 Not Cancer Driver No 1 hippie, biogrid 11 60 7 7 0
SERAC1 SERAC1 Q96JX3 Protein SERAC1 chr6 Not Cancer Driver No 1 hippie, biogrid 70 41 3 3 3
SH2D3C SH2D3C Q8N5H7 SH2 domain-containing protein 3C chr9 Not Cancer Driver No 1 hippie 110 440 72 72 0
SH3GLB1_ENST00000370558 SH3GLB1 Q9Y371 Endophilin-B1 chr1 Not Cancer Driver No 1 hippie 41 82 10 10 0
SIMC1_ENST00000443967 SIMC1 Q8NDZ2 SUMO-interacting motif-containing protein 1 chr5 Not Cancer Driver No 2 hippie, biogrid 122 493 61 61 0
SLC15A3 SLC15A3 Q8IY34 Solute carrier family 15 member 3 chr11 Not Cancer Driver No 1 hippie 63 43 1 1 0
SLC16A11 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 33 72 5 5 0
SLC25A14_ENST00000545805 SLC25A14 O95258 Brain mitochondrial carrier protein 1 chrX Not Cancer Driver No 1 hippie, biogrid 55 0 0 0 0
SLC25A16 SLC25A16 P16260 Graves disease carrier protein chr10 Not Cancer Driver No 1 hippie, biogrid 37 9 0 0 0
SLC25A30 SLC25A30 Q5SVS4 Kidney mitochondrial carrier protein 1 chr13 Not Cancer Driver No 3 hippie, biogrid 28 0 0 0 0
SMC1A SMC1A Q14683 Structural maintenance of chromosomes protein 1A chrX Census, Compendium Yes 1 hippie, biogrid 200 717 114 114 21
SMC3 SMC3 Q9UQE7 Structural maintenance of chromosomes protein 3 chr10 Not Cancer Driver No 2 hippie, biogrid 149 605 70 70 0
SMG8_ENST00000300917 SMG8 Q8ND04 Nonsense-mediated mRNA decay factor SMG8 chr17 Not Cancer Driver No 2 hippie, biogrid 145 412 57 57 1
SMN1_ENST00000503079 SMN1 Q16637-2 Isoform SMN-delta5 of Survival motor neuron protein chr5 Not Cancer Driver No 1 hippie 2 181 2 2 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 Not Cancer Driver No 1 hippie 21 107 13 13 5
SOCS6_ENST00000582322 SOCS6 O14544 Suppressor of cytokine signaling 6 chr18 Not Cancer Driver No 1 hippie 81 299 48 48 0
SPG7 SPG7 Q9UQ90 Paraplegin chr16 Not Cancer Driver No 1 hippie, biogrid 97 181 29 29 4
STARD3 STARD3 Q14849 StAR-related lipid transfer protein 3 chr17 Not Cancer Driver No 3 hippie, biogrid 51 34 6 6 0
SYNE3 SYNE3 Q6ZMZ3 Nesprin-3 chr14 Not Cancer Driver No 1 hippie, biogrid 143 236 42 42 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX Not Cancer Driver No 1 hippie 379 1152 219 219 5
TES TES Q9UGI8 Testin chr7 Not Cancer Driver No 1 hippie 56 100 7 7 0
THOC2_ENST00000355725 THOC2 Q8NI27 THO complex subunit 2 chrX Not Cancer Driver No 1 hippie 287 549 103 103 4
TK1 TK1 P04183 Thymidine kinase, cytosolic chr17 Not Cancer Driver No 1 hippie 26 13 4 4 0
TMEM106B TMEM106B Q9NUM4 Transmembrane protein 106B chr7 Not Cancer Driver No 1 hippie 31 56 4 4 1
TP53RK TP53RK Q96S44 EKC/KEOPS complex subunit TP53RK chr20 Not Cancer Driver No 1 hippie 20 51 2 2 3
TRIM14 TRIM14 Q14142 Tripartite motif-containing protein 14 chr9 Not Cancer Driver No 1 hippie 36 93 7 7 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
TRIM33 TRIM33 Q9UPN9 E3 ubiquitin-protein ligase TRIM33 chr1 Census, Compendium Yes 1 hippie 110 617 51 51 0
TTC28 TTC28 Q96AY4 Tetratricopeptide repeat protein 28 chr22 Not Cancer Driver No 3 hippie, biogrid 109 844 38 38 0
TTR TTR P02766 Transthyretin chr18 Not Cancer Driver No 1 hippie 28 25 8 8 75
TUBG1 TUBG1 P23258 Tubulin gamma-1 chain chr17 Not Cancer Driver No 1 hippie 51 44 10 10 3
USP12 USP12 O75317 Ubiquitin carboxyl-terminal hydrolase 12 chr13 Not Cancer Driver No 1 hippie, biogrid 55 33 5 5 0
VPS35 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 Not Cancer Driver No 1 hippie, biogrid 68 99 9 9 1
VPS50 VPS50 Q96JG6 Syndetin chr7 Not Cancer Driver No 1 hippie 175 171 32 32 0
WIPI2 WIPI2 Q9Y4P8 WD repeat domain phosphoinositide-interacting protein 2 chr7 Not Cancer Driver No 1 hippie 64 68 5 5 1
YWHAZ_ENST00000395956 YWHAZ P63104 14-3-3 protein zeta/delta chr8 Not Cancer Driver No 1 hippie 30 81 10 10 0
ZMYM2_ENST00000382871 ZMYM2 Q9UBW7 Zinc finger MYM-type protein 2 chr13 Census Yes 1 hippie, biogrid 144 583 68 68 0
ZNF512B ZNF512B Q96KM6 Zinc finger protein 512B chr20 Not Cancer Driver No 1 hippie 101 694 83 83 0