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SCYL3_ENST00000367770 ,SCYL3 ,Q8IZE3
  • Uniprot Accession= Q8IZE3
  • Ensembl Transcript= ENST00000367770.5
  • Uniprot Name= SCYL3
  • Name= Protein-associating with the carboxyl-terminal domain of ezrin
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 16
  • Number of Interaction partner in biogrid: 66
  • Number of Interaction partner in hippie: 81
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTR3 ACTR3 P61158 Actin-related protein 3 chr2 Not Cancer Driver No 1 hippie, biogrid 32 16 2 2 0
ARCN1 ARCN1 P48444 Coatomer subunit delta chr11 Not Cancer Driver No 1 hippie, biogrid 46 194 24 24 0
ARSF_ENST00000359361 ARSF P54793 Arylsulfatase F chrX Not Cancer Driver No 1 hippie, biogrid 132 43 10 10 0
ATG7 ATG7 O95352 Ubiquitin-like modifier-activating enzyme ATG7 chr3 Compendium Yes 1 hippie, biogrid 77 53 8 8 6
AURKA_ENST00000395915 AURKA O14965 Aurora kinase A chr20 Not Cancer Driver No 1 hippie, biogrid 36 178 21 21 0
B3GAT1_ENST00000312527 B3GAT1 Q9P2W7 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 chr11 Not Cancer Driver No 1 hippie, biogrid 85 93 32 32 0
BCKDHA BCKDHA P12694 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial chr19 Not Cancer Driver No 1 intact, hippie, biogrid 53 121 18 18 11
BET1 BET1 O15155 BET1 homolog chr7 Not Cancer Driver No 1 hippie 14 7 2 2 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 Not Cancer Driver No 1 hippie, biogrid 30 2 0 0 0
CCDC115 CCDC115 Q96NT0 Coiled-coil domain-containing protein 115 chr2 Not Cancer Driver No 1 hippie, biogrid 21 89 8 8 2
CD44 CD44 P16070 CD44 antigen chr11 Not Cancer Driver No 1 hippie 75 542 60 60 0
CEP19 CEP19 Q96LK0 Centrosomal protein of 19 kDa chr3 Not Cancer Driver No 1 intact, hippie 30 71 11 11 0
CNN3 CNN3 Q15417 Calponin-3 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 30 173 17 17 0
COPA_ENST00000241704 COPA P53621 Coatomer subunit alpha chr1 Not Cancer Driver No 1 intact, hippie, biogrid 163 157 18 18 4
COPB2 COPB2 P35606 Coatomer subunit beta' chr3 Not Cancer Driver No 1 intact, hippie, biogrid 111 114 22 22 0
COPG1 COPG1 Q9Y678 Coatomer subunit gamma-1 chr3 Not Cancer Driver No 1 hippie, biogrid 108 107 13 13 0
COPG2 COPG2 Q9UBF2 Coatomer subunit gamma-2 chr7 Not Cancer Driver No 1 hippie, biogrid 36 59 3 3 0
CXADR CXADR P78310 Coxsackievirus and adenovirus receptor chr21 Not Cancer Driver No 1 hippie, biogrid 51 98 19 19 0
CYC1 CYC1 P08574 Cytochrome c1, heme protein, mitochondrial chr8 Not Cancer Driver No 1 hippie, biogrid 65 35 8 8 2
DDX54_ENST00000306014 DDX54 Q8TDD1 ATP-dependent RNA helicase DDX54 chr12 Not Cancer Driver No 1 hippie, biogrid 113 458 52 52 0
EBAG9_ENST00000620557 EBAG9 O00559 Receptor-binding cancer antigen expressed on SiSo cells chr8 Not Cancer Driver No 1 hippie, biogrid 35 173 29 29 0
ELOVL5_ENST00000304434 ELOVL5 Q9NYP7 Elongation of very long chain fatty acids protein 5 chr6 Not Cancer Driver No 1 hippie, biogrid 34 25 4 4 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
EXOSC2 EXOSC2 Q13868 Exosome complex component RRP4 chr9 Not Cancer Driver No 1 intact, hippie, biogrid 21 47 6 6 2
EZR EZR P15311 Ezrin chr6 Census Yes 3 intact, hippie, biogrid 66 295 35 35 0
FARSB FARSB Q9NSD9 Phenylalanine--tRNA ligase beta subunit chr2 Not Cancer Driver No 1 hippie, biogrid 71 0 0 0 8
FHL2_ENST00000408995 FHL2 Q14192 Four and a half LIM domains protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 30 0 0 0 0
GABARAPL1_ENST00000545887 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 19 10 1 1 0
GABARAPL2 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 Not Cancer Driver No 1 hippie 11 2 1 1 0
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 Not Cancer Driver No 1 hippie, biogrid 86 110 26 26 50
GJD3 GJD3 Q8N144 Gap junction delta-3 protein chr17 Not Cancer Driver No 1 hippie, biogrid 5 79 0 0 0
GOLGA1 GOLGA1 Q92805 Golgin subfamily A member 1 chr9 Not Cancer Driver No 1 hippie, biogrid 99 582 77 77 0
GYS1 GYS1 P13807 Glycogen [starch] synthase, muscle chr19 Not Cancer Driver No 1 intact, hippie, biogrid 98 127 18 18 0
HDAC11 HDAC11 Q96DB2 Histone deacetylase 11 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 57 18 8 8 0
HNRNPLL HNRNPLL Q8WVV9 Heterogeneous nuclear ribonucleoprotein L-like chr2 Not Cancer Driver No 1 hippie, biogrid 37 149 13 13 0
HSD3B7 HSD3B7 Q9H2F3 3 beta-hydroxysteroid dehydrogenase type 7 chr16 Not Cancer Driver No 1 hippie, biogrid 43 27 5 5 2
INPPL1 INPPL1 O15357 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 chr11 Not Cancer Driver No 1 hippie, biogrid 174 566 76 76 4
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 Not Cancer Driver No 1 hippie 103 84 10 10 0
JPH1 JPH1 Q9HDC5 Junctophilin-1 chr8 Not Cancer Driver No 1 hippie, biogrid 131 421 89 89 0
JPH3 JPH3 Q8WXH2 Junctophilin-3 chr16 Not Cancer Driver No 1 hippie 130 534 92 92 0
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 13 96 7 7 0
LHX8 LHX8 Q68G74 LIM/homeobox protein Lhx8 chr1 Not Cancer Driver No 1 intact, hippie 93 157 47 47 0
METTL7A_ENST00000332160 METTL7A Q9H8H3 Putative methyltransferase-like protein 7A chr12 Not Cancer Driver No 1 hippie, biogrid 31 0 0 0 0
MRPS17 MRPS17 Q9Y2R5 28S ribosomal protein S17, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 14 9 3 3 0
MTCH2 MTCH2 Q9Y6C9 Mitochondrial carrier homolog 2 chr11 Not Cancer Driver No 1 hippie, biogrid 45 11 0 0 0
NCAPD3 NCAPD3 P42695 Condensin-2 complex subunit D3 chr11 Not Cancer Driver No 1 hippie, biogrid 193 304 42 42 1
NCAPH2_ENST00000420993 NCAPH2 Q6IBW4 Condensin-2 complex subunit H2 chr22 Not Cancer Driver No 1 hippie, biogrid 67 335 39 39 0
NMD3_ENST00000351193 NMD3 Q96D46 60S ribosomal export protein NMD3 chr3 Not Cancer Driver No 1 hippie, biogrid 67 104 20 20 0
NRAS NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie 284 10 0 0 14
OCLN OCLN Q16625 Occludin chr5 Not Cancer Driver No 1 biogrid 54 244 21 21 1
OTULINL OTULINL Q9NUU6 Inactive ubiquitin thioesterase OTULINL chr5 Not Cancer Driver No 1 hippie 59 21 0 0 0
PPAN PPAN Q9NQ55 Suppressor of SWI4 1 homolog chr19 Not Cancer Driver No 1 hippie, biogrid 65 257 42 42 0
PPIH PPIH O43447 Peptidyl-prolyl cis-trans isomerase H chr1 Not Cancer Driver No 1 hippie, biogrid 14 18 0 0 0
PURA PURA Q00577 Transcriptional activator protein Pur-alpha chr5 Not Cancer Driver No 1 hippie, biogrid 22 188 10 10 6
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 Not Cancer Driver No 1 hippie, biogrid 31 43 4 4 0
RAB4A RAB4A P20338 Ras-related protein Rab-4A chr1 Not Cancer Driver No 1 hippie, biogrid 26 32 11 11 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 hippie, biogrid 32 65 15 15 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 Not Cancer Driver No 1 biogrid 27 11 0 0 4
RAB9A RAB9A P51151 Ras-related protein Rab-9A chrX Not Cancer Driver No 1 hippie, biogrid 18 21 1 1 0
RAC3 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 Not Cancer Driver No 1 hippie, biogrid 24 0 0 0 4
RAP1B_ENST00000393436 RAP1B P61224 Ras-related protein Rap-1b chr12 Not Cancer Driver No 1 hippie, biogrid 26 14 3 3 0
RFX1 RFX1 P22670 MHC class II regulatory factor RFX1 chr19 Not Cancer Driver No 1 hippie, biogrid 114 536 66 66 0
SRBD1 SRBD1 Q8N5C6 S1 RNA-binding domain-containing protein 1 chr2 Not Cancer Driver No 1 hippie, biogrid 110 279 29 29 0
SRPK1 SRPK1 Q96SB4 SRSF protein kinase 1 chr6 Not Cancer Driver No 1 hippie, biogrid 73 329 32 32 0
STX6 STX6 O43752 Syntaxin-6 chr1 Not Cancer Driver No 1 hippie, biogrid 33 78 11 11 0
STX7 STX7 O15400 Syntaxin-7 chr6 Not Cancer Driver No 1 hippie, biogrid 29 164 14 14 0
STYK1 STYK1 Q6J9G0 Tyrosine-protein kinase STYK1 chr12 Not Cancer Driver No 1 intact 83 35 10 10 0
TCAF1 TCAF1 Q9Y4C2 TRPM8 channel-associated factor 1 chr7 Not Cancer Driver No 1 intact, hippie 43 18 3 3 0
TGFBRAP1 TGFBRAP1 Q8WUH2 Transforming growth factor-beta receptor-associated protein 1 chr2 Not Cancer Driver No 1 hippie, biogrid 127 37 8 8 0
TGOLN2_ENST00000377386 TGOLN2 O43493 Trans-Golgi network integral membrane protein 2 chr2 Not Cancer Driver No 1 intact, hippie 51 399 46 46 0
TMEM17 TMEM17 Q86X19 Transmembrane protein 17 chr2 Not Cancer Driver No 1 intact, hippie 22 14 2 2 0
TMEM216 TMEM216 Q9P0N5 Transmembrane protein 216 chr11 Not Cancer Driver No 1 intact, hippie 11 0 0 0 7
TRAPPC10 TRAPPC10 P48553 Trafficking protein particle complex subunit 10 chr21 Not Cancer Driver No 1 hippie, biogrid 139 174 14 14 0
TRMT2B_ENST00000545398 TRMT2B Q96GJ1 tRNA (uracil-5-)-methyltransferase homolog B chrX Not Cancer Driver No 1 hippie, biogrid 75 31 2 2 0
TXN2_ENST00000403313 TXN2 Q99757 Thioredoxin, mitochondrial chr22 Not Cancer Driver No 3 intact, hippie 22 34 4 4 0
UQCRH UQCRH P07919 Cytochrome b-c1 complex subunit 6, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 11 49 8 8 0
UTP6 UTP6 Q9NYH9 U3 small nucleolar RNA-associated protein 6 homolog chr17 Not Cancer Driver No 1 hippie, biogrid 68 28 2 2 0
VAPB VAPB O95292 Vesicle-associated membrane protein-associated protein B/C chr20 Not Cancer Driver No 1 hippie, biogrid 16 138 8 8 3
VASP VASP P50552 Vasodilator-stimulated phosphoprotein chr19 Not Cancer Driver No 1 hippie, biogrid 39 335 34 34 0
VPS11 VPS11 Q9H270 Vacuolar protein sorting-associated protein 11 homolog chr11 Not Cancer Driver No 1 hippie, biogrid 96 118 6 6 1
WDR45B WDR45B Q5MNZ6 WD repeat domain phosphoinositide-interacting protein 3 chr17 Not Cancer Driver No 1 hippie, biogrid 48 8 1 1 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
ZFPL1 ZFPL1 O95159 Zinc finger protein-like 1 chr11 Not Cancer Driver No 2 hippie, biogrid 40 127 16 16 0
ZYX ZYX Q15942 Zyxin chr7 Not Cancer Driver No 1 hippie, biogrid 83 385 52 52 0