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S100A8 ,S100A8 ,P05109
  • Uniprot Accession= P05109
  • Ensembl Transcript= ENST00000368733.3
  • Uniprot Name= S100A8
  • Name= Protein S100-A8
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 52
  • Number of Interaction partner in biogrid: 78
  • Number of Interaction partner in hippie: 171
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AGPAT1 AGPAT1 Q99943 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha chr6 Not Cancer Driver No 1 hippie, biogrid 36 38 5 5 0
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 23 20 2 2 0
ALB ALB P02768 Albumin chr4 Compendium Yes 1 hippie, biogrid 162 6 0 0 3
ANXA2_ENST00000396024 ANXA2 P07355 Annexin A2 chr15 Not Cancer Driver No 1 hippie, biogrid 49 20 4 4 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
APTX_ENST00000379819 APTX Q7Z2E3 Aprataxin chr9 Not Cancer Driver No 1 hippie, biogrid 36 101 6 6 9
ARHGEF10_ENST00000398564 ARHGEF10 O15013 Rho guanine nucleotide exchange factor 10 chr8 Census, Compendium Yes 1 intact, hippie, biogrid 175 586 78 78 1
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 Census Yes 1 hippie, biogrid 77 511 56 56 0
ASB3 ASB3 Q9Y575 Ankyrin repeat and SOCS box protein 3 chr2 Not Cancer Driver No 1 hippie, biogrid 71 0 0 0 0
ATP6AP2 ATP6AP2 O75787 Renin receptor chrX Not Cancer Driver No 1 hippie, biogrid 56 0 0 0 2
ATXN3 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 hippie 46 181 24 24 0
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 Not Cancer Driver No 1 hippie 51 63 8 8 0
AZGP1 AZGP1 P25311 Zinc-alpha-2-glycoprotein chr7 Not Cancer Driver No 1 hippie, biogrid 59 41 10 10 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie 57 571 57 57 7
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 Not Cancer Driver No 1 hippie 45 190 19 19 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BRF1 BRF1 Q92994 Transcription factor IIIB 90 kDa subunit chr14 Not Cancer Driver No 1 hippie 90 399 45 45 4
C18orf21 C18orf21 Q32NC0 UPF0711 protein C18orf21 chr18 Not Cancer Driver No 1 hippie, biogrid 21 112 12 12 0
CASP14 CASP14 P31944 Caspase-14 chr19 Not Cancer Driver No 1 hippie, biogrid 50 84 13 13 0
CCNYL1 CCNYL1 Q8N7R7 Cyclin-Y-like protein 1 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 31 100 8 8 0
CCR1 CCR1 P32246 C-C chemokine receptor type 1 chr3 Not Cancer Driver No 1 hippie, biogrid 69 14 5 5 0
CD177 CD177 Q8N6Q3 CD177 antigen chr19 Not Cancer Driver No 1 hippie 71 79 26 26 0
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 24 0 0 0 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 Not Cancer Driver No 1 hippie 48 5 1 1 0
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 Not Cancer Driver No 1 hippie 50 34 2 2 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 Census, Compendium Yes 1 intact, hippie 48 121 30 30 0
CEACAM3 CEACAM3 P40198 Carcinoembryonic antigen-related cell adhesion molecule 3 chr19 Not Cancer Driver No 1 hippie 59 56 16 16 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 3 intact, hippie 287 145 18 18 151
CHD3_ENST00000330494 CHD3 Q12873 Chromodomain-helicase-DNA-binding protein 3 chr17 Not Cancer Driver No 1 hippie 235 1015 122 122 18
CHD4 CHD4 Q14839 Chromodomain-helicase-DNA-binding protein 4 chr12 Census, Compendium Yes 1 hippie 419 974 177 177 6
CHGB CHGB P05060 Secretogranin-1 chr20 Not Cancer Driver No 1 hippie, biogrid 174 575 153 153 0
CNR2 CNR2 P34972 Cannabinoid receptor 2 chr1 Not Cancer Driver No 1 intact, hippie 57 21 4 4 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 36 32 7 7 0
CSTA CSTA P01040 Cystatin-A chr3 Not Cancer Driver No 1 hippie, biogrid 16 54 9 9 0
CUL2_ENST00000374748 CUL2 Q13617 Cullin-2 chr10 Not Cancer Driver No 1 hippie, biogrid 87 66 3 3 0
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
DCAF4 DCAF4 Q8WV16 DDB1- and CUL4-associated factor 4 chr14 Not Cancer Driver No 1 intact, hippie 59 114 11 11 0
DDX39B_ENST00000458640 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 Not Cancer Driver No 1 hippie 49 34 8 8 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DLD DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 intact, hippie, biogrid 67 17 0 0 10
DMWD DMWD Q09019 Dystrophia myotonica WD repeat-containing protein chr19 Not Cancer Driver No 1 hippie, biogrid 66 374 24 24 0
DOCK5 DOCK5 Q9H7D0 Dedicator of cytokinesis protein 5 chr8 Not Cancer Driver No 1 hippie, biogrid 278 330 45 45 0
DOCK8 DOCK8 Q8NF50 Dedicator of cytokinesis protein 8 chr9 Not Cancer Driver No 1 intact, hippie, biogrid 321 312 60 60 1
DPH6 DPH6 Q7L8W6 Diphthine--ammonia ligase chr15 Not Cancer Driver No 1 intact, hippie, biogrid 29 0 0 0 0
EDEM1 EDEM1 Q92611 ER degradation-enhancing alpha-mannosidase-like protein 1 chr3 Not Cancer Driver No 1 hippie 54 141 5 5 0
EFHD1 EFHD1 Q9BUP0 EF-hand domain-containing protein D1 chr2 Not Cancer Driver No 2 hippie, biogrid 30 94 7 7 0
ELF1 ELF1 P32519 ETS-related transcription factor Elf-1 chr13 Not Cancer Driver No 1 hippie 78 469 62 62 0
ELOB_ENST00000409906 ELOB Q15370 Elongin-B chr16 Not Cancer Driver No 1 hippie 13 69 10 10 0
ELOC ELOC Q15369 Elongin-C chr8 Not Cancer Driver No 1 hippie 22 25 5 5 0
EPAS1 EPAS1 Q99814 Endothelial PAS domain-containing protein 1 chr2 Census, Compendium Yes 1 intact, hippie, biogrid 120 449 53 53 6
ERCC3 ERCC3 P19447 General transcription and DNA repair factor IIH helicase subunit XPB chr2 Census, Compendium Yes 1 hippie, biogrid 92 208 22 22 2
ERG28 ERG28 Q9UKR5 Ergosterol biosynthetic protein 28 homolog chr14 Not Cancer Driver No 1 intact, hippie 19 3 0 0 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 2 intact, hippie 121 195 27 27 2
FABP5 FABP5 Q01469 Fatty acid-binding protein 5 chr8 Not Cancer Driver No 1 hippie, biogrid 15 4 4 4 0
FAM160A1_ENST00000505231 FHIP1A Q05DH4 FHF complex subunit HOOK interacting protein 1A chr4 Not Cancer Driver No 1 intact 47 341 8 8 0
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 176 181 14 14 3
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie 322 230 38 38 0
FNDC5_ENST00000640867 FNDC5 Q8NAU1 Fibronectin type III domain-containing protein 5 chr1 Not Cancer Driver No 1 hippie, biogrid 17 74 8 8 0
GABARAPL1_ENST00000545887 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 19 10 1 1 0
GABPA_ENST00000400075 GABPA Q06546 GA-binding protein alpha chain chr21 Not Cancer Driver No 1 hippie, biogrid 58 103 8 8 0
GAPDH GAPDH P04406 Glyceraldehyde-3-phosphate dehydrogenase chr12 Not Cancer Driver No 1 intact, hippie 39 24 3 3 0
GDF9 GDF9 O60383 Growth/differentiation factor 9 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 72 53 15 15 0
GOT1 GOT1 P17174 Aspartate aminotransferase, cytoplasmic chr10 Not Cancer Driver No 1 hippie, biogrid 56 35 5 5 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 intact, hippie 28 10 1 1 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 Not Cancer Driver No 1 intact, hippie 56 146 13 13 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 hippie 46 145 14 14 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 40 352 40 40 0
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 Not Cancer Driver No 1 hippie, biogrid 155 419 90 90 0
IGSF21 IGSF21 Q96ID5 Immunoglobulin superfamily member 21 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 119 183 47 47 0
ILK_ENST00000299421 ILK Q13418 Integrin-linked protein kinase chr11 Not Cancer Driver No 1 hippie 45 71 9 9 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 Not Cancer Driver No 1 hippie, biogrid 67 291 28 28 3
KLC2_ENST00000394067 KLC2 Q9H0B6 Kinesin light chain 2 chr11 Not Cancer Driver No 1 intact, hippie 75 344 49 49 0
KLK10_ENST00000358789 KLK10 O43240 Kallikrein-10 chr19 Not Cancer Driver No 1 hippie, biogrid 35 30 8 8 0
KMT5A KMT5A Q9NQR1-2 Isoform 2 of N-lysine methyltransferase KMT5A chr12 Not Cancer Driver No 1 intact, hippie 41 225 22 22 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 hippie 788 7 2 2 27
KRT17 KRT17 Q04695 Keratin, type I cytoskeletal 17 chr17 Not Cancer Driver No 1 hippie 86 160 31 31 18
KSR2_ENST00000339824 KSR2 Q6VAB6 Kinase suppressor of Ras 2 chr12 Not Cancer Driver No 1 intact, hippie 231 434 120 120 0
LRIF1 LRIF1 Q5T3J3 Ligand-dependent nuclear receptor-interacting factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 116 520 74 74 0
LRRK1 LRRK1 Q38SD2 Leucine-rich repeat serine/threonine-protein kinase 1 chr15 Not Cancer Driver No 1 intact, hippie, biogrid 289 261 33 33 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
LTF LTF P02788 Lactotransferrin chr3 Not Cancer Driver No 1 hippie, biogrid 131 21 4 4 0
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 Not Cancer Driver No 1 intact, hippie 74 355 44 44 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 Not Cancer Driver No 1 hippie 39 25 1 1 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 intact, hippie 128 750 126 126 18
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 104 275 38 38 1
MCM5 MCM5 P33992 DNA replication licensing factor MCM5 chr22 Not Cancer Driver No 1 hippie 88 109 20 20 1
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 Census, Compendium Yes 1 intact 226 62 15 15 19
MOB1A MOB1A Q9H8S9 MOB kinase activator 1A chr2 Not Cancer Driver No 1 intact, hippie, biogrid 16 10 2 2 0
MPO MPO P05164 Myeloperoxidase chr17 Not Cancer Driver No 1 hippie, biogrid 149 52 12 12 3
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NCF2 NCF2 P19878 Neutrophil cytosol factor 2 chr1 Not Cancer Driver No 1 hippie 97 183 34 34 14
NF2 NF2 P35240 Merlin chr22 Census, Compendium Yes 1 hippie 69 252 26 26 16
NFKBIB NFKBIB Q15653 NF-kappa-B inhibitor beta chr19 Not Cancer Driver No 1 intact, hippie 42 223 29 29 0
NFX1 NFX1 Q12986 Transcriptional repressor NF-X1 chr9 Not Cancer Driver No 1 hippie 121 491 46 46 0
NLRP7_ENST00000590030 NLRP7 Q8WX94 NACHT, LRR and PYD domains-containing protein 7 chr19 Not Cancer Driver No 1 hippie 300 71 20 20 9
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 Not Cancer Driver No 1 intact, hippie 207 201 33 33 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
NUAK1 NUAK1 O60285 NUAK family SNF1-like kinase 1 chr12 Not Cancer Driver No 1 hippie, biogrid 142 357 77 77 0
NUDT3 NUDT3 O95989 Diphosphoinositol polyphosphate phosphohydrolase 1 chr6 Not Cancer Driver No 1 hippie, biogrid 22 38 5 5 0
OCRL OCRL Q01968 Inositol polyphosphate 5-phosphatase OCRL chrX Not Cancer Driver No 1 intact, hippie, biogrid 151 126 24 24 41
OR2A4 OR2A4 O95047 Olfactory receptor 2A4 chr6 Not Cancer Driver No 1 hippie, biogrid 44 0 0 0 0
PAXIP1 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 Not Cancer Driver No 1 hippie 120 461 39 39 0
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PDCD11 PDCD11 Q14690 Protein RRP5 homolog chr10 Not Cancer Driver No 1 intact, hippie, biogrid 212 487 64 64 0
PHF11 PHF11 Q9UIL8 PHD finger protein 11 chr13 Not Cancer Driver No 1 hippie, biogrid 34 82 10 10 0
PHF21B PHF21B Q96EK2 PHD finger protein 21B chr22 Not Cancer Driver No 1 intact, hippie, biogrid 97 401 78 78 0
PIGT PIGT Q969N2 GPI transamidase component PIG-T chr20 Not Cancer Driver No 1 hippie, biogrid 51 36 6 6 1
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie, biogrid 57 99 13 13 23
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 Census, Compendium Yes 1 hippie 113 31 6 6 9
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 Not Cancer Driver No 1 hippie, biogrid 11 24 3 3 0
PPM1B PPM1B O75688 Protein phosphatase 1B chr2 Not Cancer Driver No 1 hippie, biogrid 65 243 31 31 0
PPP2R2A_ENST00000380737 PPP2R2A P63151 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform chr8 Not Cancer Driver No 1 intact, hippie 60 68 10 10 0
PPP2R2B_ENST00000394409 PPP2R2B Q00005 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform chr5 Not Cancer Driver No 2 hippie, biogrid 101 76 22 22 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 Not Cancer Driver No 1 hippie 72 124 17 17 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 110 78 15 15 31
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 50 18 1 1 0
PTDSS1 PTDSS1 P48651 Phosphatidylserine synthase 1 chr8 Not Cancer Driver No 1 hippie, biogrid 81 44 7 7 3
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 Census, Compendium Yes 1 hippie 505 76 4 4 41
RAB17 RAB17 Q9H0T7 Ras-related protein Rab-17 chr2 Not Cancer Driver No 1 intact, hippie 29 43 4 4 0
RALY RALY Q9UKM9 RNA-binding protein Raly chr20 Not Cancer Driver No 1 hippie, biogrid 58 187 32 32 0
RHBDD1 RHBDD1 Q8TEB9 Rhomboid-related protein 4 chr2 Not Cancer Driver No 1 hippie, biogrid 38 69 9 9 0
RIF1 RIF1 Q5UIP0 Telomere-associated protein RIF1 chr2 Not Cancer Driver No 1 intact, hippie 287 1355 164 164 0
RIPPLY3 RIPPLY3 P57055 Protein ripply3 chr21 Not Cancer Driver No 1 hippie, biogrid 44 190 44 44 0
RNF11 RNF11 Q9Y3C5 RING finger protein 11 chr1 Not Cancer Driver No 1 hippie 17 76 7 7 0
RNF5 RNF5 Q99942 E3 ubiquitin-protein ligase RNF5 chr6 Not Cancer Driver No 1 hippie 17 69 3 3 0
RPL26L1 RPL26L1 Q9UNX3 60S ribosomal protein L26-like 1 chr5 Not Cancer Driver No 1 hippie, biogrid 21 107 11 11 0
RPL35A RPL35A P18077 60S ribosomal protein L35a chr3 Not Cancer Driver No 1 hippie, biogrid 9 25 0 0 1
RPL36_ENST00000347512 RPL36 Q9Y3U8 60S ribosomal protein L36 chr19 Not Cancer Driver No 1 hippie, biogrid 7 66 4 4 0
RYK_ENST00000623711 RYK P34925 Tyrosine-protein kinase RYK chr3 Not Cancer Driver No 1 intact 55 85 4 4 0
S100A7_ENST00000368722 S100A7 P31151 Protein S100-A7 chr1 Census Yes 1 hippie, biogrid 39 28 14 14 0
S100A8 S100A8 P05109 Protein S100-A8 chr1 Not Cancer Driver No 1 hippie 22 8 4 4 0
S100A9 S100A9 P06702 Protein S100-A9 chr1 Not Cancer Driver No 2 hippie, biogrid 18 76 7 7 0
SARAF SARAF Q96BY9 Store-operated calcium entry-associated regulatory factor chr8 Not Cancer Driver No 1 hippie, biogrid 32 73 8 8 0
SERPINB3 SERPINB3 P29508 Serpin B3 chr18 Not Cancer Driver No 1 hippie, biogrid 142 47 28 28 0
SERPINB4 SERPINB4 P48594 Serpin B4 chr18 Not Cancer Driver No 1 hippie, biogrid 120 48 18 18 0
SH2D3A SH2D3A Q9BRG2 SH2 domain-containing protein 3A chr19 Not Cancer Driver No 1 hippie, biogrid 68 305 40 40 0
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 Not Cancer Driver No 2 intact, hippie 84 397 58 58 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 Not Cancer Driver No 1 hippie 33 164 12 12 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 48 163 15 15 0
SLC15A4 SLC15A4 Q8N697 Solute carrier family 15 member 4 chr12 Not Cancer Driver No 1 intact, hippie 66 23 4 4 0
SLC8A1_ENST00000332839 SLC8A1 P32418 Sodium/calcium exchanger 1 chr2 Not Cancer Driver No 1 hippie 305 158 48 48 0
SLX1A_ENST00000345535 SLX1A Q9BQ83-2 Isoform 2 of Structure-specific endonuclease subunit SLX1 chr16 Not Cancer Driver No 1 hippie 5 27 0 0 0
SLX1B SLX1B Q9BQ83 Structure-specific endonuclease subunit SLX1 chr16 Not Cancer Driver No 1 biogrid 3 80 1 1 0
SLX4 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 Not Cancer Driver No 1 intact, hippie 271 1573 232 232 0
SMTNL2 SMTNL2 Q2TAL5 Smoothelin-like protein 2 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 45 344 33 33 0
SPRR2E_ENST00000368750 SPRR2E P22531 Small proline-rich protein 2E chr1 Not Cancer Driver No 1 hippie, biogrid 25 0 0 0 0
SSUH2 SSUH2 Q9Y2M2 Protein SSUH2 homolog chr3 Not Cancer Driver No 1 hippie, biogrid 58 76 7 7 0
ST7 ST7 Q9NRC1 Suppressor of tumorigenicity 7 protein chr7 Not Cancer Driver No 1 hippie, biogrid 62 64 5 5 0
STK25 STK25 O00506 Serine/threonine-protein kinase 25 chr2 Not Cancer Driver No 1 hippie 42 170 15 15 0
STK3_ENST00000419617 STK3 Q13188 Serine/threonine-protein kinase 3 chr8 Not Cancer Driver No 1 hippie 70 241 32 32 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
TBC1D22B TBC1D22B Q9NU19 TBC1 domain family member 22B chr6 Not Cancer Driver No 2 intact, hippie, biogrid 55 205 27 27 0
TERF1 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 Not Cancer Driver No 1 hippie 63 220 34 34 0
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 Not Cancer Driver No 1 hippie 33 361 20 20 0
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 Compendium Yes 1 hippie 61 285 52 52 0
TMPRSS4_ENST00000437212 TMPRSS4 Q9NRS4 Transmembrane protease serine 4 chr11 Not Cancer Driver No 1 hippie, biogrid 47 35 4 4 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 intact, hippie, biogrid 2891 282 1466 1466 83
TRAF3IP1 TRAF3IP1 Q8TDR0 TRAF3-interacting protein 1 chr2 Not Cancer Driver No 1 hippie 75 507 60 60 4
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 Not Cancer Driver No 1 intact, hippie 152 149 18 18 12
TSPAN6 TSPAN6 O43657 Tetraspanin-6 chrX Not Cancer Driver No 1 hippie, biogrid 34 0 0 0 0
TUBA1A TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 1 hippie 59 52 11 11 8
TUBA4A TUBA4A P68366 Tubulin alpha-4A chain chr2 Not Cancer Driver No 1 intact, hippie 73 39 4 4 5
TUBB TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 hippie 40 63 11 11 5
TUBGCP3 TUBGCP3 Q96CW5 Gamma-tubulin complex component 3 chr13 Not Cancer Driver No 1 hippie 109 156 16 16 0
UBASH3B UBASH3B Q8TF42 Ubiquitin-associated and SH3 domain-containing protein B chr11 Not Cancer Driver No 1 intact, hippie 86 73 6 6 0
UNC119 UNC119 Q13432 Protein unc-119 homolog A chr17 Not Cancer Driver No 1 intact, hippie, biogrid 20 89 4 4 1
UPK1A_ENST00000222275 UPK1A O00322 Uroplakin-1a chr19 Not Cancer Driver No 1 hippie, biogrid 36 0 0 0 0
USF2 USF2 Q15853 Upstream stimulatory factor 2 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 30 326 29 29 0
USP15 USP15 Q9Y4E8 Ubiquitin carboxyl-terminal hydrolase 15 chr12 Not Cancer Driver No 1 hippie 136 259 39 39 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 intact, hippie 188 110 28 28 0
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 hippie, biogrid 142 117 36 36 133
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WRAP73 WRAP73 Q9P2S5 WD repeat-containing protein WRAP73 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 50 5 0 0 0
ZNF16 ZNF16 P17020 Zinc finger protein 16 chr8 Not Cancer Driver No 1 intact, hippie 99 293 40 40 0