Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AGPAT1 | AGPAT1 | Q99943 | 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 38 | 5 | 5 | 0 |
AGR2 | AGR2 | O95994 | Anterior gradient protein 2 homolog | chr7 | Not Cancer Driver | No | 1 | hippie | 23 | 20 | 2 | 2 | 0 |
ALB | ALB | P02768 | Albumin | chr4 | Compendium | Yes | 1 | hippie, biogrid | 162 | 6 | 0 | 0 | 3 |
ANXA2_ENST00000396024 | ANXA2 | P07355 | Annexin A2 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 20 | 4 | 4 | 0 |
APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | Not Cancer Driver | No | 1 | hippie | 128 | 418 | 71 | 71 | 17 |
APTX_ENST00000379819 | APTX | Q7Z2E3 | Aprataxin | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 101 | 6 | 6 | 9 |
ARHGEF10_ENST00000398564 | ARHGEF10 | O15013 | Rho guanine nucleotide exchange factor 10 | chr8 | Census, Compendium | Yes | 1 | intact, hippie, biogrid | 175 | 586 | 78 | 78 | 1 |
ARNT | ARNT | P27540 | Aryl hydrocarbon receptor nuclear translocator | chr1 | Census | Yes | 1 | hippie, biogrid | 77 | 511 | 56 | 56 | 0 |
ASB3 | ASB3 | Q9Y575 | Ankyrin repeat and SOCS box protein 3 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 71 | 0 | 0 | 0 | 0 |
ATP6AP2 | ATP6AP2 | O75787 | Renin receptor | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 0 | 0 | 0 | 2 |
ATXN3 | ATXN3 | P54252 | Ataxin-3 | chr14 | Not Cancer Driver | No | 1 | hippie | 46 | 181 | 24 | 24 | 0 |
AURKB_ENST00000585124 | AURKB | Q96GD4 | Aurora kinase B | chr17 | Not Cancer Driver | No | 1 | hippie | 51 | 63 | 8 | 8 | 0 |
AZGP1 | AZGP1 | P25311 | Zinc-alpha-2-glycoprotein | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 59 | 41 | 10 | 10 | 0 |
BAG3 | BAG3 | O95817 | BAG family molecular chaperone regulator 3 | chr10 | Not Cancer Driver | No | 1 | hippie | 57 | 571 | 57 | 57 | 7 |
BECN1_ENST00000590099 | BECN1 | Q14457 | Beclin-1 | chr17 | Not Cancer Driver | No | 1 | hippie | 45 | 190 | 19 | 19 | 0 |
BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | Census, Compendium | Yes | 1 | hippie | 77 | 98 | 16 | 16 | 0 |
BRF1 | BRF1 | Q92994 | Transcription factor IIIB 90 kDa subunit | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 399 | 45 | 45 | 4 |
C18orf21 | C18orf21 | Q32NC0 | UPF0711 protein C18orf21 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 112 | 12 | 12 | 0 |
CASP14 | CASP14 | P31944 | Caspase-14 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 50 | 84 | 13 | 13 | 0 |
CCNYL1 | CCNYL1 | Q8N7R7 | Cyclin-Y-like protein 1 | chr2 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 31 | 100 | 8 | 8 | 0 |
CCR1 | CCR1 | P32246 | C-C chemokine receptor type 1 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 69 | 14 | 5 | 5 | 0 |
CD177 | CD177 | Q8N6Q3 | CD177 antigen | chr19 | Not Cancer Driver | No | 1 | hippie | 71 | 79 | 26 | 26 | 0 |
CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 24 | 0 | 0 | 0 | 0 |
CDK5 | CDK5 | Q00535 | Cyclin-dependent kinase 5 | chr7 | Not Cancer Driver | No | 1 | hippie | 48 | 5 | 1 | 1 | 0 |
CDK9 | CDK9 | P50750 | Cyclin-dependent kinase 9 | chr9 | Not Cancer Driver | No | 1 | hippie | 50 | 34 | 2 | 2 | 0 |
CDKN1A_ENST00000373711 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | Census, Compendium | Yes | 1 | intact, hippie | 48 | 121 | 30 | 30 | 0 |
CEACAM3 | CEACAM3 | P40198 | Carcinoembryonic antigen-related cell adhesion molecule 3 | chr19 | Not Cancer Driver | No | 1 | hippie | 59 | 56 | 16 | 16 | 0 |
CFTR | CFTR | P13569 | Cystic fibrosis transmembrane conductance regulator | chr7 | Not Cancer Driver | No | 3 | intact, hippie | 287 | 145 | 18 | 18 | 151 |
CHD3_ENST00000330494 | CHD3 | Q12873 | Chromodomain-helicase-DNA-binding protein 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 235 | 1015 | 122 | 122 | 18 |
CHD4 | CHD4 | Q14839 | Chromodomain-helicase-DNA-binding protein 4 | chr12 | Census, Compendium | Yes | 1 | hippie | 419 | 974 | 177 | 177 | 6 |
CHGB | CHGB | P05060 | Secretogranin-1 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 174 | 575 | 153 | 153 | 0 |
CNR2 | CNR2 | P34972 | Cannabinoid receptor 2 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 57 | 21 | 4 | 4 | 0 |
COPS5 | COPS5 | Q92905 | COP9 signalosome complex subunit 5 | chr8 | Not Cancer Driver | No | 1 | hippie | 36 | 32 | 7 | 7 | 0 |
CSTA | CSTA | P01040 | Cystatin-A | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 54 | 9 | 9 | 0 |
CUL2_ENST00000374748 | CUL2 | Q13617 | Cullin-2 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 87 | 66 | 3 | 3 | 0 |
CYLD | CYLD | Q9NQC7 | Ubiquitin carboxyl-terminal hydrolase CYLD | chr16 | Census, Compendium | Yes | 1 | hippie | 116 | 213 | 31 | 31 | 3 |
DCAF4 | DCAF4 | Q8WV16 | DDB1- and CUL4-associated factor 4 | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 59 | 114 | 11 | 11 | 0 |
DDX39B_ENST00000458640 | DDX39B | Q13838 | Spliceosome RNA helicase DDX39B | chr6 | Not Cancer Driver | No | 1 | hippie | 49 | 34 | 8 | 8 | 0 |
DDX58 | DDX58 | O95786 | Antiviral innate immune response receptor RIG-I | chr9 | Not Cancer Driver | No | 1 | hippie | 118 | 61 | 10 | 10 | 2 |
DLD | DLD | P09622 | Dihydrolipoyl dehydrogenase, mitochondrial | chr7 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 67 | 17 | 0 | 0 | 10 |
DMWD | DMWD | Q09019 | Dystrophia myotonica WD repeat-containing protein | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 66 | 374 | 24 | 24 | 0 |
DOCK5 | DOCK5 | Q9H7D0 | Dedicator of cytokinesis protein 5 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 278 | 330 | 45 | 45 | 0 |
DOCK8 | DOCK8 | Q8NF50 | Dedicator of cytokinesis protein 8 | chr9 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 321 | 312 | 60 | 60 | 1 |
DPH6 | DPH6 | Q7L8W6 | Diphthine--ammonia ligase | chr15 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 29 | 0 | 0 | 0 | 0 |
EDEM1 | EDEM1 | Q92611 | ER degradation-enhancing alpha-mannosidase-like protein 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 54 | 141 | 5 | 5 | 0 |
EFHD1 | EFHD1 | Q9BUP0 | EF-hand domain-containing protein D1 | chr2 | Not Cancer Driver | No | 2 | hippie, biogrid | 30 | 94 | 7 | 7 | 0 |
ELF1 | ELF1 | P32519 | ETS-related transcription factor Elf-1 | chr13 | Not Cancer Driver | No | 1 | hippie | 78 | 469 | 62 | 62 | 0 |
ELOB_ENST00000409906 | ELOB | Q15370 | Elongin-B | chr16 | Not Cancer Driver | No | 1 | hippie | 13 | 69 | 10 | 10 | 0 |
ELOC | ELOC | Q15369 | Elongin-C | chr8 | Not Cancer Driver | No | 1 | hippie | 22 | 25 | 5 | 5 | 0 |
EPAS1 | EPAS1 | Q99814 | Endothelial PAS domain-containing protein 1 | chr2 | Census, Compendium | Yes | 1 | intact, hippie, biogrid | 120 | 449 | 53 | 53 | 6 |
ERCC3 | ERCC3 | P19447 | General transcription and DNA repair factor IIH helicase subunit XPB | chr2 | Census, Compendium | Yes | 1 | hippie, biogrid | 92 | 208 | 22 | 22 | 2 |
ERG28 | ERG28 | Q9UKR5 | Ergosterol biosynthetic protein 28 homolog | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 19 | 3 | 0 | 0 | 0 |
ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 2 | intact, hippie | 121 | 195 | 27 | 27 | 2 |
FABP5 | FABP5 | Q01469 | Fatty acid-binding protein 5 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 4 | 4 | 4 | 0 |
FAM160A1_ENST00000505231 | FHIP1A | Q05DH4 | FHF complex subunit HOOK interacting protein 1A | chr4 | Not Cancer Driver | No | 1 | intact | 47 | 341 | 8 | 8 | 0 |
FANCD2_ENST00000383807 | FANCD2 | Q9BXW9 | Fanconi anemia group D2 protein | chr3 | Census, Compendium | Yes | 1 | hippie | 176 | 181 | 14 | 14 | 3 |
FBXW7_ENST00000603841 | FBXW7 | Q969H0 | F-box/WD repeat-containing protein 7 | chr4 | Census, Compendium | Yes | 1 | hippie | 322 | 230 | 38 | 38 | 0 |
FNDC5_ENST00000640867 | FNDC5 | Q8NAU1 | Fibronectin type III domain-containing protein 5 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 17 | 74 | 8 | 8 | 0 |
GABARAPL1_ENST00000545887 | GABARAPL1 | Q9H0R8 | Gamma-aminobutyric acid receptor-associated protein-like 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 19 | 10 | 1 | 1 | 0 |
GABPA_ENST00000400075 | GABPA | Q06546 | GA-binding protein alpha chain | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 103 | 8 | 8 | 0 |
GAPDH | GAPDH | P04406 | Glyceraldehyde-3-phosphate dehydrogenase | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 39 | 24 | 3 | 3 | 0 |
GDF9 | GDF9 | O60383 | Growth/differentiation factor 9 | chr5 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 72 | 53 | 15 | 15 | 0 |
GOT1 | GOT1 | P17174 | Aspartate aminotransferase, cytoplasmic | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 56 | 35 | 5 | 5 | 0 |
GRB2_ENST00000392564 | GRB2 | P62993 | Growth factor receptor-bound protein 2 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 28 | 10 | 1 | 1 | 0 |
GSK3B_ENST00000264235 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 56 | 146 | 13 | 13 | 0 |
HDAC2 | HDAC2 | Q92769 | Histone deacetylase 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 46 | 145 | 14 | 14 | 0 |
HEXIM1 | HEXIM1 | O94992 | Protein HEXIM1 | chr17 | Not Cancer Driver | No | 1 | hippie | 40 | 352 | 40 | 40 | 0 |
IFI16_ENST00000295809 | IFI16 | Q16666 | Gamma-interferon-inducible protein 16 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 155 | 419 | 90 | 90 | 0 |
IGSF21 | IGSF21 | Q96ID5 | Immunoglobulin superfamily member 21 | chr1 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 119 | 183 | 47 | 47 | 0 |
ILK_ENST00000299421 | ILK | Q13418 | Integrin-linked protein kinase | chr11 | Not Cancer Driver | No | 1 | hippie | 45 | 71 | 9 | 9 | 0 |
KDM1A_ENST00000356634 | KDM1A | O60341 | Lysine-specific histone demethylase 1A | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 291 | 28 | 28 | 3 |
KLC2_ENST00000394067 | KLC2 | Q9H0B6 | Kinesin light chain 2 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 75 | 344 | 49 | 49 | 0 |
KLK10_ENST00000358789 | KLK10 | O43240 | Kallikrein-10 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 30 | 8 | 8 | 0 |
KMT5A | KMT5A | Q9NQR1-2 | Isoform 2 of N-lysine methyltransferase KMT5A | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 41 | 225 | 22 | 22 | 0 |
KRAS | KRAS | P01116 | GTPase KRas | chr12 | Census, Compendium | Yes | 1 | hippie | 788 | 7 | 2 | 2 | 27 |
KRT17 | KRT17 | Q04695 | Keratin, type I cytoskeletal 17 | chr17 | Not Cancer Driver | No | 1 | hippie | 86 | 160 | 31 | 31 | 18 |
KSR2_ENST00000339824 | KSR2 | Q6VAB6 | Kinase suppressor of Ras 2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 231 | 434 | 120 | 120 | 0 |
LRIF1 | LRIF1 | Q5T3J3 | Ligand-dependent nuclear receptor-interacting factor 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 116 | 520 | 74 | 74 | 0 |
LRRK1 | LRRK1 | Q38SD2 | Leucine-rich repeat serine/threonine-protein kinase 1 | chr15 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 289 | 261 | 33 | 33 | 0 |
LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 519 | 90 | 17 | 17 | 23 |
LTF | LTF | P02788 | Lactotransferrin | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 131 | 21 | 4 | 4 | 0 |
MAP3K3_ENST00000361733 | MAP3K3 | Q99759 | Mitogen-activated protein kinase kinase kinase 3 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 74 | 355 | 44 | 44 | 0 |
MAPK14_ENST00000229794 | MAPK14 | Q16539 | Mitogen-activated protein kinase 14 | chr6 | Not Cancer Driver | No | 1 | hippie | 39 | 25 | 1 | 1 | 0 |
MAPT_ENST00000262410 | MAPT | P10636 | Microtubule-associated protein tau | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 128 | 750 | 126 | 126 | 18 |
MCM2 | MCM2 | P49736 | DNA replication licensing factor MCM2 | chr3 | Not Cancer Driver | No | 1 | hippie | 104 | 275 | 38 | 38 | 1 |
MCM5 | MCM5 | P33992 | DNA replication licensing factor MCM5 | chr22 | Not Cancer Driver | No | 1 | hippie | 88 | 109 | 20 | 20 | 1 |
MET_ENST00000397752 | MET | P08581 | Hepatocyte growth factor receptor | chr7 | Census, Compendium | Yes | 1 | intact | 226 | 62 | 15 | 15 | 19 |
MOB1A | MOB1A | Q9H8S9 | MOB kinase activator 1A | chr2 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 16 | 10 | 2 | 2 | 0 |
MPO | MPO | P05164 | Myeloperoxidase | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 149 | 52 | 12 | 12 | 3 |
MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
NCF2 | NCF2 | P19878 | Neutrophil cytosol factor 2 | chr1 | Not Cancer Driver | No | 1 | hippie | 97 | 183 | 34 | 34 | 14 |
NF2 | NF2 | P35240 | Merlin | chr22 | Census, Compendium | Yes | 1 | hippie | 69 | 252 | 26 | 26 | 16 |
NFKBIB | NFKBIB | Q15653 | NF-kappa-B inhibitor beta | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 42 | 223 | 29 | 29 | 0 |
NFX1 | NFX1 | Q12986 | Transcriptional repressor NF-X1 | chr9 | Not Cancer Driver | No | 1 | hippie | 121 | 491 | 46 | 46 | 0 |
NLRP7_ENST00000590030 | NLRP7 | Q8WX94 | NACHT, LRR and PYD domains-containing protein 7 | chr19 | Not Cancer Driver | No | 1 | hippie | 300 | 71 | 20 | 20 | 9 |
NOS2 | NOS2 | P35228 | Nitric oxide synthase, inducible | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 207 | 201 | 33 | 33 | 0 |
NR3C1_ENST00000343796 | NR3C1 | P04150 | Glucocorticoid receptor | chr5 | Not Cancer Driver | No | 1 | hippie | 92 | 362 | 37 | 37 | 12 |
NUAK1 | NUAK1 | O60285 | NUAK family SNF1-like kinase 1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 142 | 357 | 77 | 77 | 0 |
NUDT3 | NUDT3 | O95989 | Diphosphoinositol polyphosphate phosphohydrolase 1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 38 | 5 | 5 | 0 |
OCRL | OCRL | Q01968 | Inositol polyphosphate 5-phosphatase OCRL | chrX | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 151 | 126 | 24 | 24 | 41 |
OR2A4 | OR2A4 | O95047 | Olfactory receptor 2A4 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 44 | 0 | 0 | 0 | 0 |
PAXIP1 | PAXIP1 | Q6ZW49 | PAX-interacting protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 120 | 461 | 39 | 39 | 0 |
PCLAF | PCLAF | Q15004 | PCNA-associated factor | chr15 | Not Cancer Driver | No | 1 | hippie | 20 | 111 | 20 | 20 | 0 |
PDCD11 | PDCD11 | Q14690 | Protein RRP5 homolog | chr10 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 212 | 487 | 64 | 64 | 0 |
PHF11 | PHF11 | Q9UIL8 | PHD finger protein 11 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 82 | 10 | 10 | 0 |
PHF21B | PHF21B | Q96EK2 | PHD finger protein 21B | chr22 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 97 | 401 | 78 | 78 | 0 |
PIGT | PIGT | Q969N2 | GPI transamidase component PIG-T | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 36 | 6 | 6 | 1 |
PINK1 | PINK1 | Q9BXM7 | Serine/threonine-protein kinase PINK1, mitochondrial | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 57 | 99 | 13 | 13 | 23 |
POT1 | POT1 | Q9NUX5 | Protection of telomeres protein 1 | chr7 | Census, Compendium | Yes | 1 | hippie | 113 | 31 | 6 | 6 | 9 |
PPIA | PPIA | P62937 | Peptidyl-prolyl cis-trans isomerase A | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 24 | 3 | 3 | 0 |
PPM1B | PPM1B | O75688 | Protein phosphatase 1B | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 65 | 243 | 31 | 31 | 0 |
PPP2R2A_ENST00000380737 | PPP2R2A | P63151 | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 60 | 68 | 10 | 10 | 0 |
PPP2R2B_ENST00000394409 | PPP2R2B | Q00005 | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform | chr5 | Not Cancer Driver | No | 2 | hippie, biogrid | 101 | 76 | 22 | 22 | 0 |
PRKAA1_ENST00000397128 | PRKAA1 | Q13131 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | chr5 | Not Cancer Driver | No | 1 | hippie | 72 | 124 | 17 | 17 | 0 |
PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | Not Cancer Driver | No | 1 | hippie | 110 | 78 | 15 | 15 | 31 |
PRMT1 | PRMT1 | Q99873 | Protein arginine N-methyltransferase 1 | chr19 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 50 | 18 | 1 | 1 | 0 |
PTDSS1 | PTDSS1 | P48651 | Phosphatidylserine synthase 1 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 44 | 7 | 7 | 3 |
PTEN | PTEN | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | chr10 | Census, Compendium | Yes | 1 | hippie | 505 | 76 | 4 | 4 | 41 |
RAB17 | RAB17 | Q9H0T7 | Ras-related protein Rab-17 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 29 | 43 | 4 | 4 | 0 |
RALY | RALY | Q9UKM9 | RNA-binding protein Raly | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 187 | 32 | 32 | 0 |
RHBDD1 | RHBDD1 | Q8TEB9 | Rhomboid-related protein 4 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 69 | 9 | 9 | 0 |
RIF1 | RIF1 | Q5UIP0 | Telomere-associated protein RIF1 | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 287 | 1355 | 164 | 164 | 0 |
RIPPLY3 | RIPPLY3 | P57055 | Protein ripply3 | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 44 | 190 | 44 | 44 | 0 |
RNF11 | RNF11 | Q9Y3C5 | RING finger protein 11 | chr1 | Not Cancer Driver | No | 1 | hippie | 17 | 76 | 7 | 7 | 0 |
RNF5 | RNF5 | Q99942 | E3 ubiquitin-protein ligase RNF5 | chr6 | Not Cancer Driver | No | 1 | hippie | 17 | 69 | 3 | 3 | 0 |
RPL26L1 | RPL26L1 | Q9UNX3 | 60S ribosomal protein L26-like 1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 21 | 107 | 11 | 11 | 0 |
RPL35A | RPL35A | P18077 | 60S ribosomal protein L35a | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 9 | 25 | 0 | 0 | 1 |
RPL36_ENST00000347512 | RPL36 | Q9Y3U8 | 60S ribosomal protein L36 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 7 | 66 | 4 | 4 | 0 |
RYK_ENST00000623711 | RYK | P34925 | Tyrosine-protein kinase RYK | chr3 | Not Cancer Driver | No | 1 | intact | 55 | 85 | 4 | 4 | 0 |
S100A7_ENST00000368722 | S100A7 | P31151 | Protein S100-A7 | chr1 | Census | Yes | 1 | hippie, biogrid | 39 | 28 | 14 | 14 | 0 |
S100A8 | S100A8 | P05109 | Protein S100-A8 | chr1 | Not Cancer Driver | No | 1 | hippie | 22 | 8 | 4 | 4 | 0 |
S100A9 | S100A9 | P06702 | Protein S100-A9 | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 18 | 76 | 7 | 7 | 0 |
SARAF | SARAF | Q96BY9 | Store-operated calcium entry-associated regulatory factor | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 32 | 73 | 8 | 8 | 0 |
SERPINB3 | SERPINB3 | P29508 | Serpin B3 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 142 | 47 | 28 | 28 | 0 |
SERPINB4 | SERPINB4 | P48594 | Serpin B4 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 120 | 48 | 18 | 18 | 0 |
SH2D3A | SH2D3A | Q9BRG2 | SH2 domain-containing protein 3A | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 68 | 305 | 40 | 40 | 0 |
SHC1_ENST00000368445 | SHC1 | P29353 | SHC-transforming protein 1 | chr1 | Not Cancer Driver | No | 2 | intact, hippie | 84 | 397 | 58 | 58 | 0 |
SIRT6 | SIRT6 | Q8N6T7 | NAD-dependent protein deacylase sirtuin-6 | chr19 | Not Cancer Driver | No | 1 | hippie | 33 | 164 | 12 | 12 | 0 |
SIRT7 | SIRT7 | Q9NRC8 | NAD-dependent protein deacetylase sirtuin-7 | chr17 | Not Cancer Driver | No | 1 | hippie | 48 | 163 | 15 | 15 | 0 |
SLC15A4 | SLC15A4 | Q8N697 | Solute carrier family 15 member 4 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 66 | 23 | 4 | 4 | 0 |
SLC8A1_ENST00000332839 | SLC8A1 | P32418 | Sodium/calcium exchanger 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 305 | 158 | 48 | 48 | 0 |
SLX1A_ENST00000345535 | SLX1A | Q9BQ83-2 | Isoform 2 of Structure-specific endonuclease subunit SLX1 | chr16 | Not Cancer Driver | No | 1 | hippie | 5 | 27 | 0 | 0 | 0 |
SLX1B | SLX1B | Q9BQ83 | Structure-specific endonuclease subunit SLX1 | chr16 | Not Cancer Driver | No | 1 | biogrid | 3 | 80 | 1 | 1 | 0 |
SLX4 | SLX4 | Q8IY92 | Structure-specific endonuclease subunit SLX4 | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 271 | 1573 | 232 | 232 | 0 |
SMTNL2 | SMTNL2 | Q2TAL5 | Smoothelin-like protein 2 | chr17 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 45 | 344 | 33 | 33 | 0 |
SPRR2E_ENST00000368750 | SPRR2E | P22531 | Small proline-rich protein 2E | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 0 | 0 | 0 | 0 |
SSUH2 | SSUH2 | Q9Y2M2 | Protein SSUH2 homolog | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 76 | 7 | 7 | 0 |
ST7 | ST7 | Q9NRC1 | Suppressor of tumorigenicity 7 protein | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 64 | 5 | 5 | 0 |
STK25 | STK25 | O00506 | Serine/threonine-protein kinase 25 | chr2 | Not Cancer Driver | No | 1 | hippie | 42 | 170 | 15 | 15 | 0 |
STK3_ENST00000419617 | STK3 | Q13188 | Serine/threonine-protein kinase 3 | chr8 | Not Cancer Driver | No | 1 | hippie | 70 | 241 | 32 | 32 | 0 |
SUMO2 | SUMO2 | P61956 | Small ubiquitin-related modifier 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 9 | 69 | 6 | 6 | 0 |
TBC1D22B | TBC1D22B | Q9NU19 | TBC1 domain family member 22B | chr6 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 55 | 205 | 27 | 27 | 0 |
TERF1 | TERF1 | P54274 | Telomeric repeat-binding factor 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 63 | 220 | 34 | 34 | 0 |
TERF2 | TERF2 | Q15554 | Telomeric repeat-binding factor 2 | chr16 | Not Cancer Driver | No | 1 | hippie | 33 | 361 | 20 | 20 | 0 |
TFAP4 | TFAP4 | Q01664 | Transcription factor AP-4 | chr16 | Compendium | Yes | 1 | hippie | 61 | 285 | 52 | 52 | 0 |
TMPRSS4_ENST00000437212 | TMPRSS4 | Q9NRS4 | Transmembrane protease serine 4 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 35 | 4 | 4 | 0 |
TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 1 | intact, hippie, biogrid | 2891 | 282 | 1466 | 1466 | 83 |
TRAF3IP1 | TRAF3IP1 | Q8TDR0 | TRAF3-interacting protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 75 | 507 | 60 | 60 | 4 |
TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
TRPM4 | TRPM4 | Q8TD43 | Transient receptor potential cation channel subfamily M member 4 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 152 | 149 | 18 | 18 | 12 |
TSPAN6 | TSPAN6 | O43657 | Tetraspanin-6 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 0 | 0 | 0 | 0 |
TUBA1A | TUBA1A | Q71U36 | Tubulin alpha-1A chain | chr12 | Not Cancer Driver | No | 1 | hippie | 59 | 52 | 11 | 11 | 8 |
TUBA4A | TUBA4A | P68366 | Tubulin alpha-4A chain | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 73 | 39 | 4 | 4 | 5 |
TUBB | TUBB | P07437 | Tubulin beta chain | chr6 | Not Cancer Driver | No | 1 | hippie | 40 | 63 | 11 | 11 | 5 |
TUBGCP3 | TUBGCP3 | Q96CW5 | Gamma-tubulin complex component 3 | chr13 | Not Cancer Driver | No | 1 | hippie | 109 | 156 | 16 | 16 | 0 |
UBASH3B | UBASH3B | Q8TF42 | Ubiquitin-associated and SH3 domain-containing protein B | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 86 | 73 | 6 | 6 | 0 |
UNC119 | UNC119 | Q13432 | Protein unc-119 homolog A | chr17 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 20 | 89 | 4 | 4 | 1 |
UPK1A_ENST00000222275 | UPK1A | O00322 | Uroplakin-1a | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 0 | 0 | 0 | 0 |
USF2 | USF2 | Q15853 | Upstream stimulatory factor 2 | chr19 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 30 | 326 | 29 | 29 | 0 |
USP15 | USP15 | Q9Y4E8 | Ubiquitin carboxyl-terminal hydrolase 15 | chr12 | Not Cancer Driver | No | 1 | hippie | 136 | 259 | 39 | 39 | 0 |
VCAM1 | VCAM1 | P19320 | Vascular cell adhesion protein 1 | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 188 | 110 | 28 | 28 | 0 |
VHL | VHL | P40337 | von Hippel-Lindau disease tumor suppressor | chr3 | Census, Compendium | Yes | 1 | hippie, biogrid | 142 | 117 | 36 | 36 | 133 |
VIRMA | VIRMA | Q69YN4 | Protein virilizer homolog | chr8 | Not Cancer Driver | No | 1 | hippie | 211 | 631 | 93 | 93 | 0 |
WRAP73 | WRAP73 | Q9P2S5 | WD repeat-containing protein WRAP73 | chr1 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 50 | 5 | 0 | 0 | 0 |
ZNF16 | ZNF16 | P17020 | Zinc finger protein 16 | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 99 | 293 | 40 | 40 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
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