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RUSC1 ,RUSC1 ,Q9BVN2
  • Uniprot Accession= Q9BVN2
  • Ensembl Transcript= ENST00000368352.9
  • Uniprot Name= RUSC1
  • Name= AP-4 complex accessory subunit RUSC1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 72
  • Number of Interaction partner in biogrid: 3
  • Number of Interaction partner in hippie: 103
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABHD11 ABHD11 Q8NFV4 Protein ABHD11 chr7 Not Cancer Driver No 1 intact, hippie 38 73 6 6 0
ABHD5 ABHD5 Q8WTS1 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 chr3 Not Cancer Driver No 1 intact, hippie 34 18 1 1 4
ABI2_ENST00000261018 ABI2 Q9NYB9 Abl interactor 2 chr2 Not Cancer Driver No 1 intact, hippie 56 361 38 38 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 intact, hippie 112 43 5 5 5
ADAM10 ADAM10 O14672 Disintegrin and metalloproteinase domain-containing protein 10 chr15 Not Cancer Driver No 1 intact, hippie 88 156 20 20 4
AES_ENST00000327141 TLE5 Q08117 TLE family member 5 chr19 Not Cancer Driver No 1 intact 16 77 7 7 0
AKAP8L AKAP8L Q9ULX6 A-kinase anchor protein 8-like chr19 Not Cancer Driver No 1 intact, hippie 76 510 61 61 0
ANKS1A ANKS1A Q92625 Ankyrin repeat and SAM domain-containing protein 1A chr6 Not Cancer Driver No 1 intact, hippie 120 756 75 75 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie 34 103 14 14 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
ATP6V0D2 ATP6V0D2 Q8N8Y2 V-type proton ATPase subunit d 2 chr8 Not Cancer Driver No 1 intact, hippie 81 0 0 0 0
BPIFA1_ENST00000375413 BPIFA1 Q9NP55 BPI fold-containing family A member 1 chr20 Not Cancer Driver No 1 hippie 54 0 0 0 0
C1orf109 C1orf109 Q9NX04 Uncharacterized protein C1orf109 chr1 Not Cancer Driver No 1 intact, hippie 17 0 0 0 0
CCDC120_ENST00000606812 CCDC120 Q96HB5 Coiled-coil domain-containing protein 120 chrX Not Cancer Driver No 1 intact, hippie 71 555 67 67 0
CCDC57_ENST00000392347 CCDC57 Q2TAC2 Coiled-coil domain-containing protein 57 chr17 Not Cancer Driver No 1 intact, hippie 107 595 65 65 0
CCHCR1_ENST00000376266 CCHCR1 Q8TD31 Coiled-coil alpha-helical rod protein 1 chr6 Not Cancer Driver No 1 hippie 116 565 88 88 0
CCNC CCNC P24863 Cyclin-C chr6 Census Yes 1 intact, hippie 32 33 3 3 0
CDKN2B CDKN2B P42772 Cyclin-dependent kinase 4 inhibitor B chr9 Not Cancer Driver No 1 intact, hippie 15 67 3 3 0
CMTM6 CMTM6 Q9NX76 CKLF-like MARVEL transmembrane domain-containing protein 6 chr3 Not Cancer Driver No 1 hippie 10 30 0 0 0
CREM_ENST00000429130 CREM Q03060 cAMP-responsive element modulator chr10 Not Cancer Driver No 1 intact, hippie 32 289 26 26 0
CRYBA2 CRYBA2 P53672 Beta-crystallin A2 chr2 Not Cancer Driver No 1 hippie 22 23 2 2 1
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
DMRT3 DMRT3 Q9NQL9 Doublesex- and mab-3-related transcription factor 3 chr9 Not Cancer Driver No 1 intact, hippie 94 345 71 71 0
DOK6 DOK6 Q6PKX4 Docking protein 6 chr18 Not Cancer Driver No 1 intact, hippie 98 48 11 11 0
DR1_ENST00000370267 DR1 Q01658 Protein Dr1 chr1 Not Cancer Driver No 1 hippie 21 84 12 12 0
DTX2 DTX2 Q86UW9 Probable E3 ubiquitin-protein ligase DTX2 chr7 Not Cancer Driver No 1 hippie 84 292 42 42 0
DVL2 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 Not Cancer Driver No 1 hippie 96 514 64 64 0
EXOC8 EXOC8 Q8IYI6 Exocyst complex component 8 chr1 Not Cancer Driver No 1 hippie 84 195 21 21 0
EXOSC8 EXOSC8 Q96B26 Exosome complex component RRP43 chr13 Not Cancer Driver No 1 hippie 20 28 1 1 2
FAM83H FAM83H Q6ZRV2 Protein FAM83H chr8 Not Cancer Driver No 1 intact, hippie 151 893 95 95 1
FAM9B FAM9B Q8IZU0 Protein FAM9B chrX Not Cancer Driver No 2 intact, hippie 40 130 29 29 0
FNDC3B_ENST00000416957 FNDC3B Q53EP0 Fibronectin type III domain-containing protein 3B chr3 Not Cancer Driver No 1 intact, hippie 164 433 53 53 0
GCM2 GCM2 O75603 Chorion-specific transcription factor GCMb chr6 Not Cancer Driver No 1 intact, hippie 91 272 50 50 7
GTF2B GTF2B Q00403 Transcription initiation factor IIB chr1 Not Cancer Driver No 1 intact, hippie 33 80 6 6 0
GTF3C3 GTF3C3 Q9Y5Q9 General transcription factor 3C polypeptide 3 chr2 Not Cancer Driver No 1 intact, hippie 109 195 22 22 0
HMG20A HMG20A Q9NP66 High mobility group protein 20A chr15 Not Cancer Driver No 1 hippie 58 308 44 44 0
HNRNPF_ENST00000356053 HNRNPF P52597 Heterogeneous nuclear ribonucleoprotein F chr10 Not Cancer Driver No 1 intact, hippie 65 105 18 18 0
HNRNPH2 HNRNPH2 P55795 Heterogeneous nuclear ribonucleoprotein H2 chrX Not Cancer Driver No 1 intact, hippie 73 168 34 34 3
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX Not Cancer Driver No 1 intact, hippie 6 301 6 6 22
INSC INSC Q1MX18 Protein inscuteable homolog chr11 Not Cancer Driver No 1 intact, hippie 125 34 13 13 0
KCTD9 KCTD9 Q7L273 BTB/POZ domain-containing protein KCTD9 chr8 Not Cancer Driver No 1 intact, hippie 48 27 3 3 0
KIF5B KIF5B P33176 Kinesin-1 heavy chain chr10 Census, Compendium Yes 1 intact, hippie 122 586 67 67 0
KLC1_ENST00000348520 KLC1 Q07866 Kinesin light chain 1 chr14 Not Cancer Driver No 1 intact, hippie 54 292 31 31 0
KRTAP19-1 KRTAP19-1 Q8IUB9 Keratin-associated protein 19-1 chr21 Not Cancer Driver No 1 intact, hippie 31 0 0 0 0
KRTAP19-5 KRTAP19-5 Q3LI72 Keratin-associated protein 19-5 chr21 Not Cancer Driver No 1 intact, hippie 35 0 0 0 0
KRTAP6-2 KRTAP6-2 Q3LI66 Keratin-associated protein 6-2 chr21 Not Cancer Driver No 1 intact, hippie 31 0 0 0 0
KRTAP8-1 KRTAP8-1 Q8IUC2 Keratin-associated protein 8-1 chr21 Not Cancer Driver No 1 intact, hippie 17 0 0 0 0
LIMS3_ENST00000480744 LIMS4 A0A0J9YXC7 LIM and senescent cell antigen-like-containing domain protein chr2 Not Cancer Driver No 1 intact, hippie 2 34 0 0 0
LMO2_ENST00000395833 LMO2 P25791 Rhombotin-2 chr11 Census Yes 1 intact, hippie 35 14 1 1 0
MAGEA3 MAGEA3 P43357 Melanoma-associated antigen 3 chrX Not Cancer Driver No 1 intact, hippie 79 103 18 18 0
MAGEA6 MAGEA6 P43360 Melanoma-associated antigen 6 chrX Not Cancer Driver No 1 hippie 95 103 20 20 0
MAGED1_ENST00000326587 MAGED1 Q9Y5V3 Melanoma-associated antigen D1 chrX Not Cancer Driver No 1 hippie 131 457 71 71 0
MED25 MED25 Q71SY5 Mediator of RNA polymerase II transcription subunit 25 chr19 Not Cancer Driver No 1 intact, hippie 103 432 54 54 2
MEIS2 MEIS2 O14770 Homeobox protein Meis2 chr15 Not Cancer Driver No 1 hippie 94 358 76 76 0
MISP MISP Q8IVT2 Mitotic interactor and substrate of PLK1 chr19 Not Cancer Driver No 1 intact, hippie 138 646 132 132 0
MOAP1_ENST00000298894 MOAP1 Q96BY2 Modulator of apoptosis 1 chr14 Not Cancer Driver No 1 intact, hippie 48 47 8 8 0
MORN3 MORN3 Q6PF18 MORN repeat-containing protein 3 chr12 Not Cancer Driver No 1 intact, hippie 42 63 9 9 0
MYOZ3_ENST00000517768 MYOZ3 Q8TDC0 Myozenin-3 chr5 Not Cancer Driver No 1 hippie 40 211 27 27 0
N4BP3 N4BP3 O15049 NEDD4-binding protein 3 chr5 Not Cancer Driver No 1 intact, hippie 70 474 61 61 0
NICN1_ENST00000615713 NICN1 Q9BSH3 Nicolin-1 chr3 Not Cancer Driver No 1 intact, hippie 18 10 1 1 0
NPTN NPTN Q9Y639 Neuroplastin chr15 Not Cancer Driver No 1 hippie, biogrid 47 118 9 9 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NUDT22 NUDT22 Q9BRQ3 Uridine diphosphate glucose pyrophosphatase NUDT22 chr11 Not Cancer Driver No 1 intact, hippie 23 73 6 6 0
OIP5 OIP5 O43482 Protein Mis18-beta chr15 Not Cancer Driver No 1 hippie 31 65 7 7 0
P4HA3_ENST00000331597 P4HA3 Q7Z4N8 Prolyl 4-hydroxylase subunit alpha-3 chr11 Not Cancer Driver No 1 intact, hippie 70 17 2 2 0
PFDN5 PFDN5 Q99471 Prefoldin subunit 5 chr12 Not Cancer Driver No 1 hippie 18 3 0 0 0
PIK3R3_ENST00000372006 PIK3R3 Q92569 Phosphatidylinositol 3-kinase regulatory subunit gamma chr1 Not Cancer Driver No 1 hippie 51 149 20 20 0
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 Not Cancer Driver No 1 intact, hippie 108 148 23 23 11
PM20D2 PM20D2 Q8IYS1 Xaa-Arg dipeptidase chr6 Not Cancer Driver No 1 hippie 39 79 7 7 0
PNMA1 PNMA1 Q8ND90 Paraneoplastic antigen Ma1 chr14 Not Cancer Driver No 3 intact, hippie 48 56 9 9 0
POLR1C POLR1C O15160 DNA-directed RNA polymerases I and III subunit RPAC1 chr6 Not Cancer Driver No 1 hippie 34 28 3 3 13
PRDM14 PRDM14 Q9GZV8 PR domain zinc finger protein 14 chr8 Not Cancer Driver No 1 intact, hippie 122 179 37 37 0
PRR35 PRR35 P0CG20 Proline-rich protein 35 chr16 Not Cancer Driver No 1 intact, hippie 55 487 46 46 0
RBPMS_ENST00000320203 RBPMS Q93062 RNA-binding protein with multiple splicing chr8 Not Cancer Driver No 3 intact, hippie 23 87 11 11 0
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 Census, Compendium Yes 1 hippie 64 141 35 35 3
SMYD1 SMYD1 Q8NB12 Histone-lysine N-methyltransferase SMYD1 chr2 Not Cancer Driver No 1 hippie 116 31 9 9 0
SOHLH1_ENST00000298466 SOHLH1 Q5JUK2 Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1 chr9 Not Cancer Driver No 1 intact, hippie 48 252 39 39 0
SPAG8_ENST00000396638 SPAG8 Q99932 Sperm-associated antigen 8 chr9 Not Cancer Driver No 1 intact, hippie 46 399 36 36 0
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 Not Cancer Driver No 1 hippie 35 112 14 14 12
SUOX_ENST00000356124 SUOX P51687 Sulfite oxidase, mitochondrial chr12 Not Cancer Driver No 1 intact, hippie 68 184 32 32 11
TBC1D25 TBC1D25 Q3MII6 TBC1 domain family member 25 chrX Not Cancer Driver No 1 intact, hippie 114 256 37 37 0
TCHP_ENST00000405876 TCHP Q9BT92 Trichoplein keratin filament-binding protein chr12 Not Cancer Driver No 1 hippie 60 356 50 50 0
TEKT4 TEKT4 Q8WW24 Tektin-4 chr2 Not Cancer Driver No 1 intact, hippie 93 212 45 45 0
TENT5B TENT5B Q96A09 Terminal nucleotidyltransferase 5B chr1 Not Cancer Driver No 1 intact, hippie 52 57 6 6 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 intact, hippie 67 62 7 7 0
TRAPPC6A_ENST00000585934 TRAPPC6A O75865 Trafficking protein particle complex subunit 6A chr19 Not Cancer Driver No 1 intact, hippie 28 15 3 3 0
TRIM55 TRIM55 Q9BYV6 Tripartite motif-containing protein 55 chr8 Not Cancer Driver No 1 intact, hippie, biogrid 134 276 78 78 0
TRIM63 TRIM63 Q969Q1 E3 ubiquitin-protein ligase TRIM63 chr1 Not Cancer Driver No 1 hippie, biogrid 47 71 13 13 0
TRIM73 TRIM73 Q86UV7 Tripartite motif-containing protein 73 chr7 Not Cancer Driver No 1 hippie 22 12 2 2 0
TRIM74 TRIM74 Q86UV6 Tripartite motif-containing protein 74 chr7 Not Cancer Driver No 1 hippie 25 12 1 1 0
TSSK3 TSSK3 Q96PN8 Testis-specific serine/threonine-protein kinase 3 chr1 Not Cancer Driver No 1 intact, hippie 30 0 0 0 0
TTC19 TTC19 Q6DKK2 Tetratricopeptide repeat protein 19, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie 34 76 3 3 0
TTC7B TTC7B Q86TV6 Tetratricopeptide repeat protein 7B chr14 Not Cancer Driver No 1 intact, hippie 135 124 25 25 0
UBE2S UBE2S Q16763 Ubiquitin-conjugating enzyme E2 S chr19 Not Cancer Driver No 1 intact, hippie 25 102 12 12 0
UFSP1 UFSP1 Q6NVU6 Inactive Ufm1-specific protease 1 chr7 Not Cancer Driver No 1 intact, hippie 13 13 2 2 0
VGLL3 VGLL3 A8MV65 Transcription cofactor vestigial-like protein 3 chr3 Not Cancer Driver No 1 intact, hippie 98 273 85 85 0
WDYHV1 NTAQ1 Q96HA8 Protein N-terminal glutamine amidohydrolase chr8 Not Cancer Driver No 1 intact 38 26 3 3 0
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 intact, hippie 79 108 9 9 3
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0
ZIC1 ZIC1 Q15915 Zinc finger protein ZIC 1 chr3 Not Cancer Driver No 1 intact, hippie 187 246 113 113 1
ZMYND12 ZMYND12 Q9H0C1 Zinc finger MYND domain-containing protein 12 chr1 Not Cancer Driver No 1 intact, hippie 56 0 0 0 0
ZNF34 ZNF34 Q8IZ26 Zinc finger protein 34 chr8 Not Cancer Driver No 1 hippie 62 221 23 23 0
ZNF620 ZNF620 Q6ZNG0 Zinc finger protein 620 chr3 Not Cancer Driver No 1 intact, hippie 50 125 17 17 0
ZNF765 ZNF765 Q7L2R6 Zinc finger protein 765 chr19 Not Cancer Driver No 1 intact, hippie 90 70 10 10 0
ZNF77 ZNF77 Q15935 Zinc finger protein 77 chr19 Not Cancer Driver No 1 intact, hippie 76 32 0 0 0