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RUNX3_ENST00000308873 ,RUNX3 ,Q13761
  • Uniprot Accession= Q13761
  • Ensembl Transcript= ENST00000308873.10
  • Uniprot Name= RUNX3
  • Name= Runt-related transcription factor 3
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 11
  • Number of Interaction partner in biogrid: 5
  • Number of Interaction partner in hippie: 54
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
BRD2_ENST00000374831 BRD2 P25440 Bromodomain-containing protein 2 chr6 Not Cancer Driver No 1 intact, hippie 108 632 85 85 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BTF3 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie 27 192 24 24 0
CBFB_ENST00000290858 CBFB Q13951 Core-binding factor subunit beta chr16 Census, Compendium Yes 2 hippie, biogrid 39 94 17 17 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 Census, Compendium Yes 1 intact, hippie 55 31 25 25 0
CIC CIC Q96RK0 Protein capicua homolog chr19 Census, Compendium Yes 1 hippie 276 1550 266 266 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DZIP3_ENST00000463306 DZIP3 Q86Y13 E3 ubiquitin-protein ligase DZIP3 chr3 Not Cancer Driver No 1 hippie 177 370 68 68 0
EGLN1 EGLN1 Q9GZT9 Egl nine homolog 1 chr1 Not Cancer Driver No 1 hippie 35 206 8 8 2
EGLN2_ENST00000303961 EGLN2 Q96KS0 Prolyl hydroxylase EGLN2 chr19 Not Cancer Driver No 1 hippie 52 201 17 17 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
EPS15 EPS15 P42566 Epidermal growth factor receptor substrate 15 chr1 Census, Compendium Yes 1 intact 106 543 66 66 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 Census, Compendium Yes 1 hippie 120 284 44 44 11
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 176 181 14 14 3
FANCI FANCI Q9NVI1 Fanconi anemia group I protein chr15 Not Cancer Driver No 1 hippie 161 129 20 20 2
FBXW12 FBXW12 Q6X9E4 F-box/WD repeat-containing protein 12 chr3 Not Cancer Driver No 1 hippie, biogrid 61 0 0 0 0
GLI1 GLI1 P08151 Zinc finger protein GLI1 chr12 Census, Compendium Yes 1 hippie 206 1015 184 184 0
GUCD1_ENST00000407471 GUCD1 Q96NT3 Protein GUCD1 chr22 Not Cancer Driver No 1 intact, hippie 26 11 0 0 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 1 hippie 47 135 10 10 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 hippie 46 145 14 14 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 2 intact, hippie 182 749 132 132 0
HDAC5_ENST00000586802 HDAC5 Q9UQL6 Histone deacetylase 5 chr17 Not Cancer Driver No 1 hippie 118 718 73 73 0
HDAC9_ENST00000432645 HDAC9 Q9UKV0 Histone deacetylase 9 chr7 Not Cancer Driver No 1 hippie 286 631 178 178 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 Census Yes 1 hippie 118 435 51 51 0
IKZF1 IKZF1 Q13422 DNA-binding protein Ikaros chr7 Census, Compendium Yes 1 hippie 143 326 92 92 5
IKZF3 IKZF3 Q9UKT9 Zinc finger protein Aiolos chr17 Census, Compendium Yes 1 hippie 106 284 60 60 1
IL17A IL17A Q16552 Interleukin-17A chr6 Not Cancer Driver No 1 intact 52 56 21 21 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 56 297 37 37 0
MEX3B MEX3B Q6ZN04 RNA-binding protein MEX3B chr15 Not Cancer Driver No 1 hippie 85 437 64 64 0
MYCN MYCN P04198 N-myc proto-oncogene protein chr2 Census, Compendium Yes 1 hippie 71 415 64 64 3
NANOG NANOG Q9H9S0 Homeobox protein NANOG chr12 Not Cancer Driver No 1 hippie 46 169 35 35 0
NHLRC2 NHLRC2 Q8NBF2 NHL repeat-containing protein 2 chr10 Not Cancer Driver No 1 hippie 74 103 12 12 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 Census, Compendium Yes 1 hippie 363 686 87 87 3
PHB2 PHB2 Q99623 Prohibitin-2 chr12 Not Cancer Driver No 1 hippie, biogrid 31 26 4 4 0
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 Not Cancer Driver No 1 hippie 17 115 12 12 0
PML PML P29590 Protein PML chr15 Census, Compendium Yes 1 hippie 112 312 34 34 0
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 Not Cancer Driver No 1 hippie 49 151 19 19 2
RCBTB2_ENST00000344532 RCBTB2 O95199 RCC1 and BTB domain-containing protein 2 chr13 Not Cancer Driver No 1 hippie, biogrid 86 36 3 3 0
RUNX2_ENST00000647337 RUNX2 Q13950 Runt-related transcription factor 2 chr6 Not Cancer Driver No 1 hippie, biogrid 83 447 73 73 47
RYBP RYBP Q8N488 RING1 and YY1-binding protein chr3 Not Cancer Driver No 1 hippie 37 214 37 37 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 Not Cancer Driver No 1 hippie 56 85 17 17 0
SMAD1 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 Not Cancer Driver No 1 hippie 54 161 22 22 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 Census, Compendium Yes 1 hippie 79 137 12 12 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 Census, Compendium Yes 1 hippie 97 111 19 19 5
SMAD5_ENST00000509297 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 Not Cancer Driver No 1 hippie 44 172 11 11 0
SMURF1 SMURF1 Q9HCE7 E3 ubiquitin-protein ligase SMURF1 chr7 Not Cancer Driver No 1 hippie 89 256 31 31 0
SMURF2 SMURF2 Q9HAU4 E3 ubiquitin-protein ligase SMURF2 chr17 Not Cancer Driver No 1 hippie 87 242 28 28 0
SP110_ENST00000358662 SP110 Q9HB58 Sp110 nuclear body protein chr2 Not Cancer Driver No 1 hippie 92 368 54 54 0
SUFU SUFU Q9UMX1 Suppressor of fused homolog chr10 Census Yes 1 hippie 55 199 19 19 2
SUV39H1_ENST00000376687 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX Not Cancer Driver No 1 hippie 59 15 1 1 0
TCF7L2_ENST00000355995 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 Census, Compendium Yes 1 intact, hippie 122 516 93 93 0
TCF7_ENST00000518915 TCF7 P36402-2 Isoform 4S of Transcription factor 7 chr5 Not Cancer Driver No 1 intact, hippie 37 206 30 30 0
TLE1 TLE1 Q04724 Transducin-like enhancer protein 1 chr9 Not Cancer Driver No 1 intact, hippie 111 381 53 53 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
XCL1 XCL1 P47992 Lymphotactin chr1 Not Cancer Driver No 1 intact 28 35 11 11 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 2 intact, hippie 51 489 49 49 0