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RPS27 ,RPS27 ,P42677
  • Uniprot Accession= P42677
  • Ensembl Transcript= ENST00000368567.5
  • Uniprot Name= RPS27
  • Name= 40S ribosomal protein S27
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 57
  • Number of Interaction partner in biogrid: 87
  • Number of Interaction partner in hippie: 282
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 56 28 6 6 0
ABCE1 ABCE1 P61221 ATP-binding cassette sub-family E member 1 chr4 Not Cancer Driver No 1 hippie 74 36 6 6 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 intact, hippie, biogrid 112 43 5 5 5
ACTN1_ENST00000193403 ACTN1 P12814 Alpha-actinin-1 chr14 Not Cancer Driver No 1 intact, hippie 108 195 30 30 6
ACTN4 ACTN4 O43707 Alpha-actinin-4 chr19 Not Cancer Driver No 1 intact, hippie 131 244 42 42 8
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 Not Cancer Driver No 1 intact, hippie 126 141 15 15 11
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 23 20 2 2 0
AKT3_ENST00000366539 AKT3 Q9Y243 RAC-gamma serine/threonine-protein kinase chr1 Census, Compendium Yes 1 hippie 92 131 24 24 3
ANLN ANLN Q9NQW6 Anillin chr7 Not Cancer Driver No 1 hippie 144 767 104 104 2
APC APC P25054 Adenomatous polyposis coli protein chr5 Census, Compendium Yes 1 intact, hippie 412 2406 345 345 22
ASB3 ASB3 Q9Y575 Ankyrin repeat and SOCS box protein 3 chr2 Not Cancer Driver No 1 hippie 71 0 0 0 0
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 79 239 25 25 1
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX Not Cancer Driver No 2 intact, hippie, biogrid 228 171 46 46 52
ATXN3 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 hippie 46 181 24 24 0
AURKA_ENST00000395915 AURKA O14965 Aurora kinase A chr20 Not Cancer Driver No 1 hippie 36 178 21 21 0
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 Not Cancer Driver No 1 hippie 51 63 8 8 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BLM BLM P54132 Bloom syndrome protein chr15 Census Yes 1 hippie 153 667 70 70 8
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
BTF3 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie 27 192 24 24 0
BYSL BYSL Q13895 Bystin chr6 Not Cancer Driver No 1 hippie 38 176 14 14 0
CALCOCO2_ENST00000258947 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 Not Cancer Driver No 1 hippie 42 212 19 19 0
CAND1 CAND1 Q86VP6 Cullin-associated NEDD8-dissociated protein 1 chr12 Not Cancer Driver No 1 hippie 161 88 7 7 0
CBWD1_ENST00000356521 CBWD1 Q9BRT8 COBW domain-containing protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 27 62 8 8 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 106 221 23 23 3
CD81 CD81 P60033 CD81 antigen chr11 Not Cancer Driver No 1 hippie 28 0 0 0 0
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 1 hippie 52 214 31 31 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 intact, hippie 39 23 2 2 1
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 24 0 0 0 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 Not Cancer Driver No 1 hippie 48 5 1 1 0
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 Not Cancer Driver No 1 hippie 50 34 2 2 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact, hippie 287 145 18 18 151
CHD3_ENST00000330494 CHD3 Q12873 Chromodomain-helicase-DNA-binding protein 3 chr17 Not Cancer Driver No 1 hippie 235 1015 122 122 18
CHD4 CHD4 Q14839 Chromodomain-helicase-DNA-binding protein 4 chr12 Census, Compendium Yes 1 hippie 419 974 177 177 6
CHMP4C CHMP4C Q96CF2 Charged multivesicular body protein 4c chr8 Not Cancer Driver No 1 hippie 33 224 31 31 0
CNN3 CNN3 Q15417 Calponin-3 chr1 Not Cancer Driver No 1 hippie 30 173 17 17 0
CNOT1 CNOT1 A5YKK6 CCR4-NOT transcription complex subunit 1 chr16 Not Cancer Driver No 1 intact, hippie 346 464 56 56 12
COIL COIL P38432 Coilin chr17 Not Cancer Driver No 1 hippie, biogrid 61 385 42 42 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 36 32 7 7 0
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 Not Cancer Driver No 1 hippie 41 18 1 1 0
CSNK1A1_ENST00000377843 CSNK1A1 P48729 Casein kinase I isoform alpha chr5 Not Cancer Driver No 1 hippie 44 46 3 3 0
CSNK1E CSNK1E P49674 Casein kinase I isoform epsilon chr22 Not Cancer Driver No 1 hippie 62 133 18 18 0
CSNK2A2 CSNK2A2 P19784 Casein kinase II subunit alpha' chr16 Not Cancer Driver No 1 hippie 43 13 1 1 0
CTCF CTCF P49711 Transcriptional repressor CTCF chr16 Census, Compendium Yes 1 hippie 151 481 83 83 1
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
CUL1_ENST00000602748 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 1 intact, hippie 151 65 9 9 0
CUL2_ENST00000374748 CUL2 Q13617 Cullin-2 chr10 Not Cancer Driver No 1 intact, hippie 87 66 3 3 0
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 intact, hippie 123 167 23 23 3
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
DCPS DCPS Q96C86 m7GpppX diphosphatase chr11 Not Cancer Driver No 1 hippie 48 53 6 6 1
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 34 181 23 23 0
DUSP6 DUSP6 Q16828 Dual specificity protein phosphatase 6 chr12 Not Cancer Driver No 1 hippie 43 39 3 3 4
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 104 284 33 33 0
EEF1A1 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 109 100 14 14 0
EEF1G EEF1G P26641 Elongation factor 1-gamma chr11 Not Cancer Driver No 1 hippie 44 66 5 5 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EIF2AK2_ENST00000395127 EIF2AK2 P19525 Interferon-induced, double-stranded RNA-activated protein kinase chr2 Not Cancer Driver No 1 hippie 59 188 22 22 0
EIF3CL EIF3CL B5ME19 Eukaryotic translation initiation factor 3 subunit C-like protein chr16 Not Cancer Driver No 1 hippie 4 392 2 2 0
EIF3D EIF3D O15371 Eukaryotic translation initiation factor 3 subunit D chr22 Not Cancer Driver No 1 hippie 63 200 26 26 0
ENOPH1 ENOPH1 Q9UHY7 Enolase-phosphatase E1 chr4 Not Cancer Driver No 1 hippie 35 14 2 2 0
ENTPD4 ENTPD4 Q9Y227 Ectonucleoside triphosphate diphosphohydrolase 4 chr8 Not Cancer Driver No 1 intact, hippie 67 26 2 2 0
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 Census, Compendium Yes 1 hippie 298 396 70 70 3
ERICH5 ERICH5 Q6P6B1 Glutamate-rich protein 5 chr8 Not Cancer Driver No 1 intact, hippie, biogrid 61 374 61 61 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
ESRRB_ENST00000512784 ESRRB O95718 Steroid hormone receptor ERR2 chr14 Not Cancer Driver No 1 hippie 90 35 7 7 4
FANCI FANCI Q9NVI1 Fanconi anemia group I protein chr15 Not Cancer Driver No 1 hippie, biogrid 161 129 20 20 2
FAU FAU P62861 FAU ubiquitin-like and ribosomal protein S30 chr11 Not Cancer Driver No 1 hippie 20 61 12 12 0
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 Not Cancer Driver No 1 hippie 75 243 38 38 1
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie 322 230 38 38 0
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 hippie 394 1243 185 185 8
FOXA1 FOXA1 P55317 Hepatocyte nuclear factor 3-alpha chr14 Census, Compendium Yes 1 hippie 100 295 53 53 0
FUS FUS P35637 RNA-binding protein FUS chr16 Census Yes 2 intact, hippie, biogrid 51 524 51 51 20
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 74 184 30 30 0
GRK2 GRK2 P25098 Beta-adrenergic receptor kinase 1 chr11 Not Cancer Driver No 1 hippie 77 87 8 8 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 Not Cancer Driver No 1 hippie 55 180 8 8 0
HBD HBD P02042 Hemoglobin subunit delta chr11 Not Cancer Driver No 1 hippie, biogrid 56 7 2 2 0
HEATR1 HEATR1 Q9H583 HEAT repeat-containing protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 291 43 5 5 0
HEATR6 HEATR6 Q6AI08 HEAT repeat-containing protein 6 chr17 Not Cancer Driver No 1 hippie, biogrid 124 250 28 28 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 40 352 40 40 0
HKDC1 HKDC1 Q2TB90 Hexokinase HKDC1 chr10 Not Cancer Driver No 1 hippie, biogrid 146 33 3 3 0
HNRNPA0 HNRNPA0 Q13151 Heterogeneous nuclear ribonucleoprotein A0 chr5 Not Cancer Driver No 1 hippie 25 172 14 14 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 Not Cancer Driver No 2 intact, hippie 77 504 45 45 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie 149 251 52 52 0
HSPA9 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 Not Cancer Driver No 1 hippie 67 283 26 26 2
IBTK IBTK Q9P2D0 Inhibitor of Bruton tyrosine kinase chr6 Not Cancer Driver No 1 intact, hippie 146 364 39 39 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 Not Cancer Driver No 1 hippie 183 265 37 37 6
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX Not Cancer Driver No 1 intact, hippie 6 301 6 6 22
ILK_ENST00000299421 ILK Q13418 Integrin-linked protein kinase chr11 Not Cancer Driver No 1 hippie 45 71 9 9 0
IMMP2L_ENST00000452895 IMMP2L Q96T52 Mitochondrial inner membrane protease subunit 2 chr7 Not Cancer Driver No 1 hippie 36 29 7 7 0
INS INS P01308 Insulin chr11 Not Cancer Driver No 1 hippie 15 5 1 1 22
ITFG1 ITFG1 Q8TB96 T-cell immunomodulatory protein chr16 Not Cancer Driver No 1 hippie 70 18 3 3 0
KDM6B_ENST00000448097 KDM6B O15054 Lysine-specific demethylase 6B chr17 Not Cancer Driver No 1 hippie 189 1278 142 142 2
KIAA0556 KATNIP O60303 Katanin-interacting protein chr16 Not Cancer Driver No 1 intact 240 982 137 137 0
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
KIF23 KIF23 Q02241 Kinesin-like protein KIF23 chr15 Not Cancer Driver No 1 hippie 102 559 62 62 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 58 350 44 44 0
LDB3_ENST00000361373 LDB3 O75112 LIM domain-binding protein 3 chr10 Not Cancer Driver No 1 hippie 107 529 71 71 4
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 2 intact, hippie 519 90 17 17 23
LTV1 LTV1 Q96GA3 Protein LTV1 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 45 388 30 30 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 Not Cancer Driver No 1 hippie 22 0 0 0 1
MAP3K1 MAP3K1 Q13233 Mitogen-activated protein kinase kinase kinase 1 chr5 Census, Compendium Yes 1 hippie 184 820 62 62 3
MAP3K14 MAP3K14 Q99558 Mitogen-activated protein kinase kinase kinase 14 chr17 Not Cancer Driver No 1 intact, hippie 94 543 52 52 0
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 Not Cancer Driver No 1 intact, hippie 74 355 44 44 0
MAPK6 MAPK6 Q16659 Mitogen-activated protein kinase 6 chr15 Not Cancer Driver No 1 hippie 79 165 20 20 0
MARS MARS1 P56192 Methionine--tRNA ligase, cytoplasmic chr12 Not Cancer Driver No 1 intact 91 151 16 16 8
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 104 275 38 38 1
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 intact, hippie 56 297 37 37 0
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 Not Cancer Driver No 1 hippie 76 446 42 42 0
METTL14 METTL14 Q9HCE5 N6-adenosine-methyltransferase non-catalytic subunit chr4 Not Cancer Driver No 1 hippie 60 224 26 26 0
MROH1 MROH1 Q8NDA8 Maestro heat-like repeat-containing protein family member 1 chr8 Not Cancer Driver No 1 hippie, biogrid 52 67 0 0 0
MRPS18C MRPS18C Q9Y3D5 28S ribosomal protein S18c, mitochondrial chr4 Not Cancer Driver No 1 hippie 16 5 1 1 0
MTCH2 MTCH2 Q9Y6C9 Mitochondrial carrier homolog 2 chr11 Not Cancer Driver No 1 hippie 45 11 0 0 0
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NACAD NACAD O15069 NAC-alpha domain-containing protein 1 chr7 Not Cancer Driver No 1 intact, hippie 72 1465 69 69 0
NCBP1 NCBP1 Q09161 Nuclear cap-binding protein subunit 1 chr9 Not Cancer Driver No 1 intact 88 89 8 8 0
NCL NCL P19338 Nucleolin chr2 Not Cancer Driver No 1 hippie 85 569 68 68 0
NEDD8 NEDD8 Q15843 NEDD8 chr14 Not Cancer Driver No 1 hippie 10 36 5 5 0
NEK4 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 Not Cancer Driver No 1 hippie 78 492 49 49 0
NFKB2 NFKB2 Q00653 Nuclear factor NF-kappa-B p100 subunit chr10 Census, Compendium Yes 1 intact, hippie 86 510 46 46 0
NFKBIA NFKBIA P25963 NF-kappa-B inhibitor alpha chr14 Compendium Yes 1 hippie 37 102 9 9 1
NFX1 NFX1 Q12986 Transcriptional repressor NF-X1 chr9 Not Cancer Driver No 1 hippie 121 491 46 46 0
NOP56 NOP56 O00567 Nucleolar protein 56 chr20 Not Cancer Driver No 1 intact, hippie 83 191 34 34 0
NPM1 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 intact, hippie 29 249 22 22 0
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NSG2 NSG2 Q9Y328 Neuronal vesicle trafficking-associated protein 2 chr5 Not Cancer Driver No 1 hippie 34 43 9 9 0
NUBPL NUBPL Q8TB37 Iron-sulfur protein NUBPL chr14 Not Cancer Driver No 1 hippie, biogrid 32 49 1 1 2
OXSR1 OXSR1 O95747 Serine/threonine-protein kinase OSR1 chr3 Not Cancer Driver No 1 hippie 69 208 29 29 0
PAG1 PAG1 Q9NWQ8 Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 chr8 Not Cancer Driver No 2 intact, hippie, biogrid 58 394 54 54 0
PAN2_ENST00000548043 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 Not Cancer Driver No 1 hippie 139 78 10 10 0
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 70 43 6 6 20
PEX3 PEX3 P56589 Peroxisomal biogenesis factor 3 chr6 Not Cancer Driver No 1 hippie, biogrid 31 24 0 0 2
PHKG2 PHKG2 P15735 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform chr16 Not Cancer Driver No 1 hippie 48 50 6 6 4
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 Census, Compendium Yes 1 hippie 1669 38 11 11 30
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PNO1 PNO1 Q9NRX1 RNA-binding protein PNO1 chr2 Not Cancer Driver No 1 hippie 30 85 10 10 0
POLE4 POLE4 Q9NR33 DNA polymerase epsilon subunit 4 chr2 Not Cancer Driver No 1 hippie, biogrid 4 45 1 1 0
POLR1E POLR1E Q9GZS1 DNA-directed RNA polymerase I subunit RPA49 chr9 Not Cancer Driver No 1 hippie, biogrid 39 85 6 6 0
POLR2C POLR2C P19387 DNA-directed RNA polymerase II subunit RPB3 chr16 Not Cancer Driver No 1 hippie, biogrid 34 108 11 11 0
POTEF POTEF A5A3E0 POTE ankyrin domain family member F chr2 Not Cancer Driver No 2 intact, hippie, biogrid 269 453 93 93 0
PPBP PPBP P02775 Platelet basic protein chr4 Not Cancer Driver No 1 hippie 30 21 8 8 0
PPP2R2B_ENST00000394409 PPP2R2B Q00005 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform chr5 Not Cancer Driver No 1 hippie 101 76 22 22 0
PPP2R5D PPP2R5D Q14738 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform chr6 Not Cancer Driver No 2 intact, hippie, biogrid 64 178 13 13 4
PPP2R5E PPP2R5E Q16537 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform chr14 Not Cancer Driver No 1 intact, hippie, biogrid 68 86 20 20 0
PRC1 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 Not Cancer Driver No 1 hippie 63 235 26 26 0
PRDM11_ENST00000530656 PRDM11 Q9NQV5 PR domain-containing protein 11 chr11 Not Cancer Driver No 1 intact, hippie, biogrid 93 236 40 40 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 Not Cancer Driver No 1 hippie 72 124 17 17 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 Census Yes 1 hippie 53 24 0 0 2
PRKACB_ENST00000370689 PRKACB P22694 cAMP-dependent protein kinase catalytic subunit beta chr1 Not Cancer Driver No 1 hippie 50 26 6 6 4
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 Compendium Yes 1 hippie 79 43 9 9 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 110 78 15 15 31
PRPF8 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie 255 225 26 26 8
PRSS8 PRSS8 Q16651 Prostasin chr16 Not Cancer Driver No 1 hippie, biogrid 30 27 3 3 0
PSME3_ENST00000590720 PSME3 P61289 Proteasome activator complex subunit 3 chr17 Not Cancer Driver No 1 intact, hippie 20 25 5 5 0
PTBP1_ENST00000349038 PTBP1 P26599 Polypyrimidine tract-binding protein 1 chr19 Not Cancer Driver No 1 hippie 74 154 17 17 0
PTBP3_ENST00000374255 PTBP3 O95758 Polypyrimidine tract-binding protein 3 chr9 Not Cancer Driver No 1 intact, hippie 61 114 9 9 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 Census, Compendium Yes 1 hippie 505 76 4 4 41
PYM1 PYM1 Q9BRP8 Partner of Y14 and mago chr12 Not Cancer Driver No 1 hippie 22 204 22 22 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 Not Cancer Driver No 1 intact, hippie 32 65 15 15 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 Not Cancer Driver No 1 hippie 34 13 0 0 0
RANBP9 RANBP9 Q96S59 Ran-binding protein 9 chr6 Not Cancer Driver No 1 hippie 73 413 30 30 0
RBX1 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 Not Cancer Driver No 1 hippie 10 18 1 1 0
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 Not Cancer Driver No 1 hippie 158 796 115 115 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 Not Cancer Driver No 1 hippie 128 703 81 81 0
RIN3 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 intact, hippie 137 417 61 61 0
RIOK2 RIOK2 Q9BVS4 Serine/threonine-protein kinase RIO2 chr5 Not Cancer Driver No 1 hippie 68 253 33 33 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 Not Cancer Driver No 1 intact, hippie 66 295 39 39 0
RIPK4_ENST00000352483 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 intact, hippie 119 232 34 34 3
RMC1 RMC1 Q96DM3 Regulator of MON1-CCZ1 complex chr18 Not Cancer Driver No 1 hippie 70 12 0 0 0
RNF31 RNF31 Q96EP0 E3 ubiquitin-protein ligase RNF31 chr14 Not Cancer Driver No 1 hippie 142 319 45 45 0
RPL10A RPL10A P62906 60S ribosomal protein L10a chr6 Not Cancer Driver No 1 hippie, biogrid 22 16 0 0 0
RPL10_ENST00000369817 RPL10 P27635 60S ribosomal protein L10 chrX Census, Compendium Yes 2 intact, hippie, biogrid 46 9 3 3 4
RPL11 RPL11 P62913 60S ribosomal protein L11 chr1 Not Cancer Driver No 1 hippie, biogrid 27 12 1 1 1
RPL12 RPL12 P30050 60S ribosomal protein L12 chr9 Not Cancer Driver No 1 hippie, biogrid 13 75 6 6 0
RPL13A RPL13A P40429 60S ribosomal protein L13a chr19 Not Cancer Driver No 1 hippie, biogrid 27 33 2 2 0
RPL13_ENST00000393099 RPL13 P26373 60S ribosomal protein L13 chr16 Not Cancer Driver No 1 hippie, biogrid 14 160 11 11 1
RPL14_ENST00000396203 RPL14 P50914 60S ribosomal protein L14 chr3 Not Cancer Driver No 1 hippie, biogrid 21 129 13 13 0
RPL15_ENST00000413699 RPL15 P61313 60S ribosomal protein L15 chr3 Not Cancer Driver No 1 hippie, biogrid 18 84 9 9 0
RPL18 RPL18 Q07020 60S ribosomal protein L18 chr19 Not Cancer Driver No 1 hippie, biogrid 16 98 6 6 0
RPL18A RPL18A Q02543 60S ribosomal protein L18a chr19 Not Cancer Driver No 1 hippie, biogrid 28 25 4 4 0
RPL21_ENST00000326092 RPL21 P46778 60S ribosomal protein L21 chr13 Not Cancer Driver No 1 hippie, biogrid 15 103 11 11 1
RPL22 RPL22 P35268 60S ribosomal protein L22 chr1 Census, Compendium Yes 1 hippie, biogrid 26 15 1 1 0
RPL23A RPL23A P62750 60S ribosomal protein L23a chr17 Not Cancer Driver No 2 hippie, biogrid 21 70 13 13 0
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 Not Cancer Driver No 1 hippie, biogrid 14 29 4 4 0
RPL24 RPL24 P83731 60S ribosomal protein L24 chr3 Not Cancer Driver No 1 hippie, biogrid 19 105 14 14 0
RPL27A RPL27A P46776 60S ribosomal protein L27a chr11 Not Cancer Driver No 1 hippie, biogrid 7 56 2 2 0
RPL27_ENST00000253788 RPL27 P61353 60S ribosomal protein L27 chr17 Not Cancer Driver No 1 hippie, biogrid 21 13 3 3 0
RPL3 RPL3 P39023 60S ribosomal protein L3 chr22 Not Cancer Driver No 1 hippie, biogrid 34 79 3 3 0
RPL30 RPL30 P62888 60S ribosomal protein L30 chr8 Not Cancer Driver No 1 hippie, biogrid 4 11 0 0 0
RPL31_ENST00000264258 RPL31 P62899 60S ribosomal protein L31 chr2 Not Cancer Driver No 1 hippie, biogrid 19 69 14 14 0
RPL34_ENST00000502534 RPL34 P49207 60S ribosomal protein L34 chr4 Not Cancer Driver No 1 hippie, biogrid 11 31 1 1 0
RPL35 RPL35 P42766 60S ribosomal protein L35 chr9 Not Cancer Driver No 2 hippie, biogrid 12 65 9 9 0
RPL35A RPL35A P18077 60S ribosomal protein L35a chr3 Not Cancer Driver No 1 hippie, biogrid 9 25 0 0 1
RPL36AL RPL36AL Q969Q0 60S ribosomal protein L36a-like chr14 Not Cancer Driver No 1 hippie, biogrid 9 64 7 7 0
RPL38_ENST00000439590 RPL38 P63173 60S ribosomal protein L38 chr17 Not Cancer Driver No 1 hippie, biogrid 2 9 0 0 0
RPL4 RPL4 P36578 60S ribosomal protein L4 chr15 Not Cancer Driver No 1 hippie, biogrid 49 222 31 31 0
RPL5_ENST00000370321 RPL5 P46777 60S ribosomal protein L5 chr1 Census Yes 1 hippie, biogrid 57 96 17 17 2
RPL6 RPL6 Q02878 60S ribosomal protein L6 chr12 Not Cancer Driver No 1 hippie, biogrid 41 159 24 24 0
RPL7 RPL7 P18124 60S ribosomal protein L7 chr8 Not Cancer Driver No 1 hippie, biogrid 24 40 4 4 0
RPL7A RPL7A P62424 60S ribosomal protein L7a chr9 Not Cancer Driver No 1 hippie, biogrid 27 100 5 5 0
RPL8_ENST00000528957 RPL8 P62917 60S ribosomal protein L8 chr8 Not Cancer Driver No 1 hippie, biogrid 32 115 17 17 0
RPL9 RPL9 Q53Z07 60S ribosomal protein L9 chr4 Not Cancer Driver No 1 hippie, biogrid 30 3 0 0 0
RPLP0_ENST00000228306 RPLP0 P05388 60S acidic ribosomal protein P0 chr12 Not Cancer Driver No 1 hippie, biogrid 44 36 4 4 0
RPLP2_ENST00000530797 RPLP2 P05387 60S acidic ribosomal protein P2 chr11 Not Cancer Driver No 1 hippie, biogrid 12 59 5 5 0
RPS10_ENST00000467531 RPS10 P46783 40S ribosomal protein S10 chr6 Not Cancer Driver No 1 hippie 25 100 19 19 0
RPS11 RPS11 P62280 40S ribosomal protein S11 chr19 Not Cancer Driver No 1 hippie, biogrid 18 6 0 0 0
RPS12 RPS12 P25398 40S ribosomal protein S12 chr6 Not Cancer Driver No 1 hippie 17 0 0 0 0
RPS13 RPS13 P62277 40S ribosomal protein S13 chr11 Not Cancer Driver No 2 hippie, biogrid 19 18 5 5 0
RPS14_ENST00000521466 RPS14 P62263 40S ribosomal protein S14 chr5 Not Cancer Driver No 2 hippie, biogrid 14 96 13 13 0
RPS15A_ENST00000565420 RPS15A P62244 40S ribosomal protein S15a chr16 Not Cancer Driver No 1 hippie 6 4 0 0 0
RPS15_ENST00000592588 RPS15 P62841 40S ribosomal protein S15 chr19 Not Cancer Driver No 1 hippie, biogrid 13 59 7 7 0
RPS16 RPS16 P62249 40S ribosomal protein S16 chr19 Not Cancer Driver No 2 hippie, biogrid 16 14 1 1 0
RPS18 RPS18 P62269 40S ribosomal protein S18 chr6 Not Cancer Driver No 2 hippie, biogrid 28 27 8 8 0
RPS19_ENST00000600467 RPS19 P39019 40S ribosomal protein S19 chr19 Not Cancer Driver No 1 hippie, biogrid 15 61 3 3 23
RPS2 RPS2 P15880 40S ribosomal protein S2 chr16 Not Cancer Driver No 1 hippie, biogrid 34 85 14 14 0
RPS20_ENST00000521262 RPS20 P60866 40S ribosomal protein S20 chr8 Not Cancer Driver No 2 hippie, biogrid 18 53 8 8 0
RPS23 RPS23 P62266 40S ribosomal protein S23 chr5 Not Cancer Driver No 2 hippie, biogrid 8 35 1 1 2
RPS24_ENST00000613865 RPS24 P62847 40S ribosomal protein S24 chr10 Not Cancer Driver No 1 hippie 13 88 10 10 0
RPS25 RPS25 P62851 40S ribosomal protein S25 chr11 Not Cancer Driver No 1 hippie, biogrid 16 60 8 8 0
RPS26_ENST00000646449 RPS26 P62854 40S ribosomal protein S26 chr12 Not Cancer Driver No 1 hippie 9 52 5 5 2
RPS27 RPS27 P42677 40S ribosomal protein S27 chr1 Not Cancer Driver No 1 hippie 10 29 7 7 0
RPS27L RPS27L Q71UM5 40S ribosomal protein S27-like chr15 Not Cancer Driver No 1 hippie 4 22 2 2 0
RPS28 RPS28 P62857 40S ribosomal protein S28 chr19 Not Cancer Driver No 1 hippie 7 55 5 5 0
RPS3A RPS3A P61247 40S ribosomal protein S3a chr4 Compendium Yes 2 hippie, biogrid 21 85 5 5 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 Not Cancer Driver No 2 hippie, biogrid 22 48 4 4 0
RPS4X RPS4X P62701 40S ribosomal protein S4, X isoform chrX Not Cancer Driver No 2 hippie, biogrid 32 35 6 6 0
RPS5_ENST00000601521 RPS5 P46782 40S ribosomal protein S5 chr19 Not Cancer Driver No 1 hippie 38 40 8 8 0
RPS6 RPS6 P62753 40S ribosomal protein S6 chr9 Not Cancer Driver No 2 hippie, biogrid 38 150 25 25 0
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 Not Cancer Driver No 1 hippie 94 178 32 32 0
RPS7_ENST00000645674 RPS7 P62081 40S ribosomal protein S7 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 29 39 7 7 0
RPS8 RPS8 P62241 40S ribosomal protein S8 chr1 Not Cancer Driver No 2 hippie, biogrid 23 81 7 7 0
RPS9_ENST00000391752 RPS9 P46781 40S ribosomal protein S9 chr19 Not Cancer Driver No 2 hippie, biogrid 23 34 5 5 0
RPSA_ENST00000301821 RPSA P08865 40S ribosomal protein SA chr3 Not Cancer Driver No 1 hippie, biogrid 22 95 6 6 5
RRP1B RRP1B Q14684 Ribosomal RNA processing protein 1 homolog B chr21 Not Cancer Driver No 1 intact, hippie 74 513 48 48 0
RTN4 RTN4 Q9NQC3 Reticulon-4 chr2 Not Cancer Driver No 1 hippie 121 866 82 82 0
SKIL_ENST00000259119 SKIL P12757 Ski-like protein chr3 Not Cancer Driver No 1 intact, hippie 77 356 32 32 0
SLC16A11 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 33 72 5 5 0
SND1 SND1 Q7KZF4 Staphylococcal nuclease domain-containing protein 1 chr7 Census Yes 1 hippie 127 258 48 48 0
SNRNP70 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 Not Cancer Driver No 1 hippie 38 416 37 37 0
SPRTN SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 Not Cancer Driver No 1 hippie 73 252 38 38 1
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 2 intact, hippie, biogrid 53 130 11 11 1
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
STK24 STK24 Q9Y6E0 Serine/threonine-protein kinase 24 chr13 Not Cancer Driver No 1 hippie 67 118 16 16 0
STK25 STK25 O00506 Serine/threonine-protein kinase 25 chr2 Not Cancer Driver No 1 hippie 42 170 15 15 0
STK26 STK26 Q9P289 Serine/threonine-protein kinase 26 chrX Not Cancer Driver No 1 hippie 62 119 18 18 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 Not Cancer Driver No 1 hippie 70 231 30 30 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
TAB2_ENST00000637181 TAB2 Q9NYJ8 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 chr6 Not Cancer Driver No 1 intact, hippie 87 573 73 73 2
TEX101_ENST00000598265 TEX101 Q9BY14 Testis-expressed protein 101 chr19 Not Cancer Driver No 1 hippie 45 2 0 0 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 Not Cancer Driver No 1 hippie 41 41 4 4 10
TMEM41B_ENST00000611268 TMEM41B Q5BJD5 Transmembrane protein 41B chr11 Not Cancer Driver No 1 hippie 19 47 3 3 0
TMPRSS5 TMPRSS5 Q9H3S3 Transmembrane protease serine 5 chr11 Not Cancer Driver No 1 hippie, biogrid 46 33 1 1 0
TNF TNF P01375 Tumor necrosis factor chr6 Not Cancer Driver No 1 hippie 24 45 3 3 0
TNFRSF1A TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 Not Cancer Driver No 1 intact, hippie 58 111 15 15 12
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 Not Cancer Driver No 1 intact, hippie 48 229 28 28 0
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 43 316 36 36 0
TOLLIP TOLLIP Q9H0E2 Toll-interacting protein chr11 Not Cancer Driver No 1 hippie 38 81 12 12 0
TOM1_ENST00000449058 TOM1 O60784 Target of Myb protein 1 chr22 Not Cancer Driver No 1 intact, hippie 70 324 41 41 0
TP53RK TP53RK Q96S44 EKC/KEOPS complex subunit TP53RK chr20 Not Cancer Driver No 1 hippie 20 51 2 2 3
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TRADD TRADD Q15628 Tumor necrosis factor receptor type 1-associated DEATH domain protein chr16 Not Cancer Driver No 1 intact, hippie 26 74 5 5 0
TSR1 TSR1 Q2NL82 Pre-rRNA-processing protein TSR1 homolog chr17 Not Cancer Driver No 1 hippie 74 332 32 32 0
TUBA1A TUBA1A Q71U36 Tubulin alpha-1A chain chr12 Not Cancer Driver No 3 intact, hippie, biogrid 59 52 11 11 8
TUBA4A TUBA4A P68366 Tubulin alpha-4A chain chr2 Not Cancer Driver No 2 intact, hippie, biogrid 73 39 4 4 5
TUBB TUBB P07437 Tubulin beta chain chr6 Not Cancer Driver No 1 hippie, biogrid 40 63 11 11 5
TUBB3 TUBB3 Q13509 Tubulin beta-3 chain chr16 Not Cancer Driver No 2 intact, hippie, biogrid 67 53 10 10 12
TUBB8 TUBB8 Q3ZCM7 Tubulin beta-8 chain chr10 Not Cancer Driver No 2 intact, hippie, biogrid 103 53 18 18 13
TUBGCP3 TUBGCP3 Q96CW5 Gamma-tubulin complex component 3 chr13 Not Cancer Driver No 1 hippie 109 156 16 16 0
TUBGCP4 TUBGCP4 Q9UGJ1 Gamma-tubulin complex component 4 chr15 Not Cancer Driver No 1 hippie 79 62 5 5 0
UBD UBD O15205 Ubiquitin D chr6 Not Cancer Driver No 1 hippie 31 8 1 1 0
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 hippie 30 32 6 6 0
UBL4A UBL4A P11441 Ubiquitin-like protein 4A chrX Not Cancer Driver No 1 hippie 22 16 5 5 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 intact, hippie 188 110 28 28 0
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 hippie 142 117 36 36 133
VRK1 VRK1 Q99986 Serine/threonine-protein kinase VRK1 chr14 Not Cancer Driver No 1 hippie 52 80 9 9 0
WDCP WDCP Q9H6R7 WD repeat and coiled-coil-containing protein chr2 Census Yes 1 intact, hippie 77 126 9 9 0
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0
ZBTB1 ZBTB1 Q9Y2K1 Zinc finger and BTB domain-containing protein 1 chr14 Not Cancer Driver No 1 hippie 70 271 27 27 0
ZBTB2 ZBTB2 Q8N680 Zinc finger and BTB domain-containing protein 2 chr6 Not Cancer Driver No 1 hippie 75 216 30 30 0
ZBTB38_ENST00000441582 ZBTB38 Q8NAP3 Zinc finger and BTB domain-containing protein 38 chr3 Not Cancer Driver No 1 hippie 137 648 73 73 0
ZC3H18_ENST00000301011 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 1 hippie 139 929 134 134 0
ZNF131 ZNF131 P52739 Zinc finger protein 131 chr5 Not Cancer Driver No 1 hippie 79 266 41 41 0