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RPRD2 ,RPRD2 ,Q5VT52
  • Uniprot Accession= Q5VT52
  • Ensembl Transcript= ENST00000369068.4
  • Uniprot Name= RPRD2
  • Name= Regulation of nuclear pre-mRNA domain-containing protein 2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 23
  • Number of Interaction partner in biogrid: 69
  • Number of Interaction partner in hippie: 109
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 114 48 19 19 11
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie, biogrid 196 443 88 88 169
B9D2 B9D2 Q9BPU9 B9 domain-containing protein 2 chr19 Not Cancer Driver No 1 intact, hippie 36 4 4 4 1
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 Not Cancer Driver No 1 hippie, biogrid 17 112 9 9 0
CNOT9_ENST00000273064 CNOT9 Q92600 CCR4-NOT transcription complex subunit 9 chr2 Compendium Yes 1 hippie 42 30 0 0 0
CRCP CRCP O75575 DNA-directed RNA polymerase III subunit RPC9 chr7 Not Cancer Driver No 1 hippie, biogrid 11 113 4 4 0
CSNK2A1_ENST00000400217 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 Not Cancer Driver No 1 intact, hippie 71 75 8 8 4
CTDSP1 CTDSP1 Q9GZU7 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 chr2 Not Cancer Driver No 1 hippie 34 46 2 2 0
CTR9 CTR9 Q6PD62 RNA polymerase-associated protein CTR9 homolog chr11 Not Cancer Driver No 1 intact, hippie 164 385 48 48 0
DCPS DCPS Q96C86 m7GpppX diphosphatase chr11 Not Cancer Driver No 1 hippie 48 53 6 6 1
DGCR8 DGCR8 Q8WYQ5 Microprocessor complex subunit DGCR8 chr22 Census, Compendium Yes 1 hippie, biogrid 102 466 57 57 0
DHX8 DHX8 Q14562 ATP-dependent RNA helicase DHX8 chr17 Not Cancer Driver No 1 hippie, biogrid 138 490 72 72 0
DYNC1H1 DYNC1H1 Q14204 Cytoplasmic dynein 1 heavy chain 1 chr14 Not Cancer Driver No 1 intact, hippie 505 495 62 62 21
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
GPN1_ENST00000610189 GPN1 Q9HCN4 GPN-loop GTPase 1 chr2 Not Cancer Driver No 1 hippie, biogrid 39 117 14 14 0
GPN3_ENST00000228827 GPN3 Q9UHW5 GPN-loop GTPase 3 chr12 Not Cancer Driver No 1 hippie, biogrid 28 19 0 0 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 hippie 46 145 14 14 0
HIF1AN HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 Not Cancer Driver No 2 hippie, biogrid 37 77 9 9 0
HIST1H1B H1-5 P16401 Histone H1.5 chr6 Not Cancer Driver No 1 intact 66 224 66 66 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 Not Cancer Driver No 1 hippie, biogrid 24 200 13 13 0
HSPA2_ENST00000247207 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 Not Cancer Driver No 1 hippie, biogrid 93 286 38 38 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 2 intact, hippie, biogrid 149 251 52 52 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
LEO1 LEO1 Q8WVC0 RNA polymerase-associated protein LEO1 chr15 Not Cancer Driver No 1 intact, hippie 74 611 69 69 0
LMO2_ENST00000395833 LMO2 P25791 Rhombotin-2 chr11 Census Yes 2 intact, hippie, biogrid 35 14 1 1 0
MDC1 MDC1 Q14676 Mediator of DNA damage checkpoint protein 1 chr6 Not Cancer Driver No 1 hippie 249 1829 223 223 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 Not Cancer Driver No 1 hippie, biogrid 162 1104 117 117 0
MED10 MED10 Q9BTT4 Mediator of RNA polymerase II transcription subunit 10 chr5 Not Cancer Driver No 1 hippie, biogrid 14 13 3 3 0
MED14 MED14 O60244 Mediator of RNA polymerase II transcription subunit 14 chrX Not Cancer Driver No 1 hippie, biogrid 182 318 45 45 0
MED17 MED17 Q9NVC6 Mediator of RNA polymerase II transcription subunit 17 chr11 Not Cancer Driver No 1 hippie, biogrid 75 182 17 17 1
MED20 MED20 Q9H944 Mediator of RNA polymerase II transcription subunit 20 chr6 Not Cancer Driver No 1 hippie, biogrid 22 0 0 0 0
MED21 MED21 Q13503 Mediator of RNA polymerase II transcription subunit 21 chr12 Not Cancer Driver No 1 hippie, biogrid 12 46 3 3 0
MED26 MED26 O95402 Mediator of RNA polymerase II transcription subunit 26 chr19 Not Cancer Driver No 1 hippie, biogrid 71 541 61 61 0
MED27 MED27 Q6P2C8 Mediator of RNA polymerase II transcription subunit 27 chr9 Not Cancer Driver No 1 hippie, biogrid 34 61 5 5 0
MED28 MED28 Q9H204 Mediator of RNA polymerase II transcription subunit 28 chr4 Not Cancer Driver No 1 hippie, biogrid 24 101 18 18 0
MED4 MED4 Q9NPJ6 Mediator of RNA polymerase II transcription subunit 4 chr13 Not Cancer Driver No 1 hippie, biogrid 29 161 17 17 0
MED8_ENST00000372457 MED8 Q96G25 Mediator of RNA polymerase II transcription subunit 8 chr1 Not Cancer Driver No 1 hippie, biogrid 29 191 24 24 0
MPG MPG P29372 DNA-3-methyladenine glycosylase chr16 Not Cancer Driver No 1 hippie 35 141 21 21 0
MTNR1B MTNR1B P49286 Melatonin receptor type 1B chr11 Not Cancer Driver No 1 intact, hippie 104 8 1 1 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NCBP1 NCBP1 Q09161 Nuclear cap-binding protein subunit 1 chr9 Not Cancer Driver No 1 intact, hippie 88 89 8 8 0
NINL NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 1 hippie 230 881 150 150 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NUP50 NUP50 Q9UKX7 Nuclear pore complex protein Nup50 chr22 Not Cancer Driver No 1 hippie, biogrid 58 333 40 40 0
PDRG1 PDRG1 Q9NUG6 p53 and DNA damage-regulated protein 1 chr20 Not Cancer Driver No 1 hippie, biogrid 17 46 9 9 0
PFDN2 PFDN2 Q9UHV9 Prefoldin subunit 2 chr1 Not Cancer Driver No 1 hippie, biogrid 18 111 11 11 0
PHRF1 PHRF1 Q9P1Y6 PHD and RING finger domain-containing protein 1 chr11 Not Cancer Driver No 1 hippie 238 1414 194 194 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 30 157 13 13 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
POLR1A POLR1A O95602 DNA-directed RNA polymerase I subunit RPA1 chr2 Not Cancer Driver No 1 hippie, biogrid 208 361 64 64 2
POLR1B_ENST00000263331 POLR1B Q9H9Y6 DNA-directed RNA polymerase I subunit RPA2 chr2 Not Cancer Driver No 1 hippie, biogrid 120 69 10 10 2
POLR1C POLR1C O15160 DNA-directed RNA polymerases I and III subunit RPAC1 chr6 Not Cancer Driver No 1 hippie, biogrid 34 28 3 3 13
POLR1D POLR1D P0DPB6 DNA-directed RNA polymerases I and III subunit RPAC2 chr13 Not Cancer Driver No 1 hippie, biogrid 17 87 13 13 7
POLR1E POLR1E Q9GZS1 DNA-directed RNA polymerase I subunit RPA49 chr9 Not Cancer Driver No 1 hippie, biogrid 39 85 6 6 0
POLR2A POLR2A P24928-2 Isoform 2 of DNA-directed RNA polymerase II subunit RPB1 chr17 Census Yes 1 hippie, biogrid 56 230 20 20 0
POLR2B_ENST00000314595 POLR2B P30876 DNA-directed RNA polymerase II subunit RPB2 chr4 Not Cancer Driver No 1 hippie, biogrid 166 173 25 25 0
POLR2C POLR2C P19387 DNA-directed RNA polymerase II subunit RPB3 chr16 Not Cancer Driver No 1 hippie, biogrid 34 108 11 11 0
POLR2D POLR2D O15514 DNA-directed RNA polymerase II subunit RPB4 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 13 54 2 2 0
POLR2E POLR2E P19388 DNA-directed RNA polymerases I, II, and III subunit RPABC1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 31 36 3 3 0
POLR2F_ENST00000442738 POLR2F P61218 DNA-directed RNA polymerases I, II, and III subunit RPABC2 chr22 Not Cancer Driver No 1 hippie, biogrid 22 57 13 13 0
POLR2G POLR2G P62487 DNA-directed RNA polymerase II subunit RPB7 chr11 Not Cancer Driver No 5 intact, hippie, biogrid 15 15 1 1 0
POLR2H_ENST00000456318 POLR2H P52434 DNA-directed RNA polymerases I, II, and III subunit RPABC3 chr3 Not Cancer Driver No 1 hippie, biogrid 16 14 1 1 0
POLR2I POLR2I P36954 DNA-directed RNA polymerase II subunit RPB9 chr19 Not Cancer Driver No 1 hippie, biogrid 21 22 5 5 0
POLR2J POLR2J P52435 DNA-directed RNA polymerase II subunit RPB11-a chr7 Not Cancer Driver No 2 hippie, biogrid 12 0 0 0 0
POLR2K POLR2K P53803 DNA-directed RNA polymerases I, II, and III subunit RPABC4 chr8 Not Cancer Driver No 1 hippie, biogrid 10 11 1 1 0
POLR2L POLR2L P62875 DNA-directed RNA polymerases I, II, and III subunit RPABC5 chr11 Not Cancer Driver No 2 hippie, biogrid 10 0 0 0 0
POLR2M_ENST00000464277 POLR2M Q6EEV4 DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5 chr15 Not Cancer Driver No 2 intact, hippie, biogrid 4 121 4 4 0
POLR3A POLR3A O14802 DNA-directed RNA polymerase III subunit RPC1 chr10 Not Cancer Driver No 1 hippie, biogrid 155 113 17 17 15
POLR3B POLR3B Q9NW08 DNA-directed RNA polymerase III subunit RPC2 chr12 Not Cancer Driver No 1 hippie, biogrid 164 117 20 20 8
POLR3D POLR3D P05423 DNA-directed RNA polymerase III subunit RPC4 chr8 Not Cancer Driver No 1 hippie, biogrid 33 303 24 24 0
POLR3E POLR3E Q9NVU0 DNA-directed RNA polymerase III subunit RPC5 chr16 Not Cancer Driver No 1 hippie, biogrid 84 308 40 40 0
POLR3H_ENST00000396504 POLR3H Q9Y535 DNA-directed RNA polymerase III subunit RPC8 chr22 Not Cancer Driver No 1 hippie, biogrid 23 33 6 6 0
POLR3K POLR3K Q9Y2Y1 DNA-directed RNA polymerase III subunit RPC10 chr16 Not Cancer Driver No 1 hippie, biogrid 10 0 0 0 1
POTEI POTEI P0CG38 POTE ankyrin domain family member I chr2 Not Cancer Driver No 1 hippie, biogrid 14 449 6 6 0
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 1 intact, hippie 38 27 6 6 0
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 1 hippie 26 23 4 4 0
RAVER1_ENST00000615032 RAVER1 Q8IY67 Ribonucleoprotein PTB-binding 1 chr19 Not Cancer Driver No 1 intact 61 330 22 22 0
RECQL5 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 Not Cancer Driver No 1 hippie, biogrid 132 495 71 71 0
RNGTT RNGTT O60942 mRNA-capping enzyme chr6 Not Cancer Driver No 1 hippie, biogrid 69 112 12 12 0
RPA1 RPA1 P27694 Replication protein A 70 kDa DNA-binding subunit chr17 Not Cancer Driver No 1 hippie 51 98 6 6 0
RPA2_ENST00000373912 RPA2 P15927 Replication protein A 32 kDa subunit chr1 Not Cancer Driver No 1 hippie 28 114 16 16 0
RPA3 RPA3 P35244 Replication protein A 14 kDa subunit chr7 Not Cancer Driver No 1 hippie 13 4 1 1 0
RPAP2 RPAP2 Q8IXW5 Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 56 293 25 25 0
RPAP3 RPAP3 Q9H6T3 RNA polymerase II-associated protein 3 chr12 Not Cancer Driver No 1 hippie, biogrid 59 334 37 37 0
RPRD1A RPRD1A Q96P16 Regulation of nuclear pre-mRNA domain-containing protein 1A chr18 Not Cancer Driver No 1 intact, hippie, biogrid 49 86 16 16 0
RPRD1B RPRD1B Q9NQG5 Regulation of nuclear pre-mRNA domain-containing protein 1B chr20 Not Cancer Driver No 4 intact, hippie, biogrid 34 155 16 16 0
RPS6KL1_ENST00000557413 RPS6KL1 Q9Y6S9 Ribosomal protein S6 kinase-like 1 chr14 Not Cancer Driver No 1 intact, hippie, biogrid 60 161 16 16 0
S100A2_ENST00000368709 S100A2 P29034 Protein S100-A2 chr1 Not Cancer Driver No 1 hippie, biogrid 16 6 2 2 0
S100A4_ENST00000354332 S100A4 P26447 Protein S100-A4 chr1 Not Cancer Driver No 1 hippie, biogrid 9 6 2 2 0
S100A6_ENST00000496817 S100A6 P06703 Protein S100-A6 chr1 Not Cancer Driver No 1 hippie, biogrid 5 4 0 0 0
SCAF1 SCAF1 Q9H7N4 Splicing factor, arginine/serine-rich 19 chr19 Not Cancer Driver No 1 hippie, biogrid 135 1307 134 134 0
SCAF4 SCAF4 O95104 SR-related and CTD-associated factor 4 chr21 Not Cancer Driver No 1 hippie, biogrid 162 938 132 132 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 Not Cancer Driver No 1 hippie 33 164 12 12 0
SMG7_ENST00000347615 SMG7 Q92540 Nonsense-mediated mRNA decay factor SMG7 chr1 Not Cancer Driver No 1 hippie 134 664 82 82 0
SP7 SP7 Q8TDD2 Transcription factor Sp7 chr12 Not Cancer Driver No 1 intact, hippie 63 332 44 44 0
SPOP SPOP O43791 Speckle-type POZ protein chr17 Census, Compendium Yes 1 hippie 147 25 5 5 6
SPTB_ENST00000389721 SPTB P11277 Spectrin beta chain, erythrocytic chr14 Not Cancer Driver No 1 hippie, biogrid 328 562 70 70 7
STRAP STRAP Q9Y3F4 Serine-threonine kinase receptor-associated protein chr12 Not Cancer Driver No 2 hippie, biogrid 44 40 5 5 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SUPT5H SUPT5H O00267 Transcription elongation factor SPT5 chr19 Not Cancer Driver No 1 hippie 165 572 87 87 0
SUPT6H SUPT6H Q7KZ85 Transcription elongation factor SPT6 chr17 Not Cancer Driver No 1 hippie, biogrid 222 761 107 107 0
TRIM37 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 Not Cancer Driver No 1 hippie 119 492 60 60 3
UPF1 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 Not Cancer Driver No 1 intact, hippie 146 329 36 36 0
URI1 URI1 O94763 Unconventional prefoldin RPB5 interactor 1 chr19 Not Cancer Driver No 1 hippie, biogrid 88 388 64 64 0
UXT_ENST00000333119 UXT Q9UBK9 Protein UXT chrX Not Cancer Driver No 1 hippie, biogrid 21 17 1 1 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 Not Cancer Driver No 1 intact, hippie 79 108 9 9 3
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 Not Cancer Driver No 1 hippie 66 140 12 12 0