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RPAP2 ,RPAP2 ,Q8IXW5
  • Uniprot Accession= Q8IXW5
  • Ensembl Transcript= ENST00000610020.1
  • Uniprot Name= RPAP2
  • Name= Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 27
  • Number of Interaction partner in biogrid: 113
  • Number of Interaction partner in hippie: 134
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie, biogrid 112 43 5 5 5
APOC3 APOC3 P02656 Apolipoprotein C-III chr11 Not Cancer Driver No 1 intact, hippie, biogrid 14 12 2 2 1
ARMC5_ENST00000563544 ARMC5 Q96C12 Armadillo repeat-containing protein 5 chr16 Not Cancer Driver No 1 hippie, biogrid 135 267 41 41 17
ARMCX3_ENST00000537169 ARMCX3 Q9UH62 Armadillo repeat-containing X-linked protein 3 chrX Not Cancer Driver No 1 hippie, biogrid 39 77 7 7 0
ASB6 ASB6 Q9NWX5 Ankyrin repeat and SOCS box protein 6 chr9 Not Cancer Driver No 2 intact, hippie, biogrid 35 31 3 3 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
BRD1_ENST00000216267 BRD1 O95696 Bromodomain-containing protein 1 chr22 Not Cancer Driver No 1 hippie 171 425 68 68 0
CCNF CCNF P41002 Cyclin-F chr16 Not Cancer Driver No 1 hippie, biogrid 106 221 23 23 3
CCT5 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 Not Cancer Driver No 1 hippie, biogrid 83 72 10 10 1
CCT8L2 CCT8L2 Q96SF2 T-complex protein 1 subunit theta-like 2 chr22 Not Cancer Driver No 1 hippie, biogrid 216 104 46 46 0
CDK19 CDK19 Q9BWU1 Cyclin-dependent kinase 19 chr6 Not Cancer Driver No 1 hippie, biogrid 63 191 28 28 8
CEP120 CEP120 Q8N960 Centrosomal protein of 120 kDa chr5 Not Cancer Driver No 1 hippie 102 448 52 52 1
CNTRL_ENST00000238341 CNTRL Q7Z7A1 Centriolin chr9 Census Yes 1 hippie 234 1556 159 159 0
CPNE2_ENST00000535318 CPNE2 Q96FN4 Copine-2 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 62 32 4 4 0
CRCP CRCP O75575 DNA-directed RNA polymerase III subunit RPC9 chr7 Not Cancer Driver No 1 hippie, biogrid 11 113 4 4 0
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 Census Yes 1 hippie, biogrid 138 270 43 43 22
DXO_ENST00000375356 DXO O77932 Decapping and exoribonuclease protein chr6 Not Cancer Driver No 3 hippie, biogrid 46 143 17 17 0
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EHBP1 EHBP1 Q8NDI1 EH domain-binding protein 1 chr2 Not Cancer Driver No 1 hippie, biogrid 148 914 115 115 0
EIF4A2 EIF4A2 Q14240 Eukaryotic initiation factor 4A-II chr3 Census Yes 1 hippie, biogrid 77 27 14 14 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
FAM168A FAM168A Q92567 Protein FAM168A chr11 Not Cancer Driver No 1 hippie, biogrid 17 139 11 11 0
FGF11 FGF11 Q92914 Fibroblast growth factor 11 chr17 Not Cancer Driver No 1 hippie, biogrid 20 68 5 5 0
FGFR1OP CEP43 O95684 Centrosomal protein 43 chr6 Not Cancer Driver No 1 intact 43 272 33 33 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 85 352 65 65 0
GCOM1_ENST00000380569 GCOM1 P0CAP1-11 Isoform 11 of Myocardial zonula adherens protein chr15 Not Cancer Driver No 1 hippie 96 462 83 83 0
GPN1_ENST00000610189 GPN1 Q9HCN4 GPN-loop GTPase 1 chr2 Not Cancer Driver No 3 hippie, biogrid 39 117 14 14 0
GPN3_ENST00000228827 GPN3 Q9UHW5 GPN-loop GTPase 3 chr12 Not Cancer Driver No 5 intact, hippie, biogrid 28 19 0 0 0
GTF3C3 GTF3C3 Q9Y5Q9 General transcription factor 3C polypeptide 3 chr2 Not Cancer Driver No 1 hippie, biogrid 109 195 22 22 0
HELLS_ENST00000348459 HELLS Q9NRZ9 Lymphoid-specific helicase chr10 Not Cancer Driver No 1 hippie, biogrid 78 227 25 25 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
INTS1 INTS1 Q8N201 Integrator complex subunit 1 chr7 Not Cancer Driver No 1 hippie, biogrid 234 368 43 43 1
INTS3_ENST00000435409 INTS3 Q68E01 Integrator complex subunit 3 chr1 Not Cancer Driver No 1 hippie, biogrid 125 213 25 25 0
INTS4 INTS4 Q96HW7 Integrator complex subunit 4 chr11 Not Cancer Driver No 1 hippie, biogrid 117 82 7 7 0
INTS7 INTS7 Q9NVH2 Integrator complex subunit 7 chr1 Not Cancer Driver No 1 hippie, biogrid 106 88 17 17 0
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 Not Cancer Driver No 1 hippie 95 335 42 42 0
KHDRBS2 KHDRBS2 Q5VWX1 KH domain-containing, RNA-binding, signal transduction-associated protein 2 chr6 Not Cancer Driver No 1 hippie, biogrid 168 268 140 140 0
KHDRBS3 KHDRBS3 O75525 KH domain-containing, RNA-binding, signal transduction-associated protein 3 chr8 Not Cancer Driver No 1 hippie, biogrid 64 230 40 40 0
KRT8_ENST00000546897 KRT8 P05787 Keratin, type II cytoskeletal 8 chr12 Not Cancer Driver No 1 hippie, biogrid 65 221 37 37 3
KSR2_ENST00000339824 KSR2 Q6VAB6 Kinase suppressor of Ras 2 chr12 Not Cancer Driver No 1 intact, hippie 231 434 120 120 0
LMO2_ENST00000395833 LMO2 P25791 Rhombotin-2 chr11 Census Yes 2 intact, hippie, biogrid 35 14 1 1 0
LRCH2 LRCH2 Q5VUJ6 Leucine-rich repeat and calponin homology domain-containing protein 2 chrX Not Cancer Driver No 1 hippie, biogrid 128 458 77 77 0
MAPRE3 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 Not Cancer Driver No 1 hippie, biogrid 37 120 16 16 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 Not Cancer Driver No 3 hippie, biogrid 162 1104 117 117 0
MED10 MED10 Q9BTT4 Mediator of RNA polymerase II transcription subunit 10 chr5 Not Cancer Driver No 1 hippie, biogrid 14 13 3 3 0
MED13 MED13 Q9UHV7 Mediator of RNA polymerase II transcription subunit 13 chr17 Not Cancer Driver No 1 hippie, biogrid 288 905 127 127 3
MED13L MED13L Q71F56 Mediator of RNA polymerase II transcription subunit 13-like chr12 Not Cancer Driver No 1 hippie, biogrid 274 1074 142 142 0
MED14 MED14 O60244 Mediator of RNA polymerase II transcription subunit 14 chrX Not Cancer Driver No 1 hippie, biogrid 182 318 45 45 0
MED15 MED15 Q96RN5 Mediator of RNA polymerase II transcription subunit 15 chr22 Not Cancer Driver No 1 hippie, biogrid 95 558 72 72 0
MED17 MED17 Q9NVC6 Mediator of RNA polymerase II transcription subunit 17 chr11 Not Cancer Driver No 3 hippie, biogrid 75 182 17 17 1
MED18_ENST00000398997 MED18 Q9BUE0 Mediator of RNA polymerase II transcription subunit 18 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 35 10 2 2 0
MED20 MED20 Q9H944 Mediator of RNA polymerase II transcription subunit 20 chr6 Not Cancer Driver No 1 hippie, biogrid 22 0 0 0 0
MED21 MED21 Q13503 Mediator of RNA polymerase II transcription subunit 21 chr12 Not Cancer Driver No 2 hippie, biogrid 12 46 3 3 0
MED22_ENST00000343730 MED22 Q15528 Mediator of RNA polymerase II transcription subunit 22 chr9 Not Cancer Driver No 1 hippie, biogrid 26 98 12 12 0
MED24_ENST00000394128 MED24 O75448 Mediator of RNA polymerase II transcription subunit 24 chr17 Not Cancer Driver No 1 hippie, biogrid 101 76 0 0 0
MED26 MED26 O95402 Mediator of RNA polymerase II transcription subunit 26 chr19 Not Cancer Driver No 2 hippie, biogrid 71 541 61 61 0
MED27 MED27 Q6P2C8 Mediator of RNA polymerase II transcription subunit 27 chr9 Not Cancer Driver No 1 hippie, biogrid 34 61 5 5 0
MED28 MED28 Q9H204 Mediator of RNA polymerase II transcription subunit 28 chr4 Not Cancer Driver No 2 hippie, biogrid 24 101 18 18 0
MED30 MED30 Q96HR3 Mediator of RNA polymerase II transcription subunit 30 chr8 Not Cancer Driver No 1 hippie, biogrid 20 93 8 8 0
MED31 MED31 Q9Y3C7 Mediator of RNA polymerase II transcription subunit 31 chr17 Not Cancer Driver No 1 hippie, biogrid 16 15 1 1 0
MED4 MED4 Q9NPJ6 Mediator of RNA polymerase II transcription subunit 4 chr13 Not Cancer Driver No 2 hippie, biogrid 29 161 17 17 0
MED6_ENST00000256379 MED6 O75586 Mediator of RNA polymerase II transcription subunit 6 chr14 Not Cancer Driver No 1 hippie, biogrid 21 79 4 4 0
MED7 MED7 O43513 Mediator of RNA polymerase II transcription subunit 7 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 32 132 19 19 0
MED8_ENST00000372457 MED8 Q96G25 Mediator of RNA polymerase II transcription subunit 8 chr1 Not Cancer Driver No 1 hippie, biogrid 29 191 24 24 0
MED9 MED9 Q9NWA0 Mediator of RNA polymerase II transcription subunit 9 chr17 Not Cancer Driver No 2 hippie, biogrid 16 127 15 15 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 Not Cancer Driver No 1 hippie 150 711 79 79 0
NELFE NELFE P18615 Negative elongation factor E chr6 Not Cancer Driver No 1 hippie, biogrid 47 352 45 45 0
NEURL4 NEURL4 Q96JN8 Neuralized-like protein 4 chr17 Not Cancer Driver No 1 intact, hippie 217 751 119 119 0
OFD1 OFD1 O75665 Oral-facial-digital syndrome 1 protein chrX Not Cancer Driver No 1 hippie 129 476 58 58 5
PDRG1 PDRG1 Q9NUG6 p53 and DNA damage-regulated protein 1 chr20 Not Cancer Driver No 2 hippie, biogrid 17 46 9 9 0
PFDN2 PFDN2 Q9UHV9 Prefoldin subunit 2 chr1 Not Cancer Driver No 1 hippie, biogrid 18 111 11 11 0
PFN1 PFN1 P07737 Profilin-1 chr17 Not Cancer Driver No 1 hippie, biogrid 16 7 1 1 3
PHRF1 PHRF1 Q9P1Y6 PHD and RING finger domain-containing protein 1 chr11 Not Cancer Driver No 1 hippie 238 1414 194 194 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 7 intact, hippie, biogrid 30 157 13 13 0
PLEKHF2 PLEKHF2 Q9H8W4 Pleckstrin homology domain-containing family F member 2 chr8 Not Cancer Driver No 1 hippie 32 36 4 4 0
POLR1A POLR1A O95602 DNA-directed RNA polymerase I subunit RPA1 chr2 Not Cancer Driver No 1 hippie, biogrid 208 361 64 64 2
POLR1B_ENST00000263331 POLR1B Q9H9Y6 DNA-directed RNA polymerase I subunit RPA2 chr2 Not Cancer Driver No 1 hippie, biogrid 120 69 10 10 2
POLR1C POLR1C O15160 DNA-directed RNA polymerases I and III subunit RPAC1 chr6 Not Cancer Driver No 1 hippie, biogrid 34 28 3 3 13
POLR1D POLR1D P0DPB6 DNA-directed RNA polymerases I and III subunit RPAC2 chr13 Not Cancer Driver No 1 hippie, biogrid 17 87 13 13 7
POLR1E POLR1E Q9GZS1 DNA-directed RNA polymerase I subunit RPA49 chr9 Not Cancer Driver No 1 hippie, biogrid 39 85 6 6 0
POLR2A POLR2A P24928-2 Isoform 2 of DNA-directed RNA polymerase II subunit RPB1 chr17 Census Yes 3 intact, hippie, biogrid 56 230 20 20 0
POLR2B_ENST00000314595 POLR2B P30876 DNA-directed RNA polymerase II subunit RPB2 chr4 Not Cancer Driver No 2 intact, hippie, biogrid 166 173 25 25 0
POLR2C POLR2C P19387 DNA-directed RNA polymerase II subunit RPB3 chr16 Not Cancer Driver No 3 intact, hippie, biogrid 34 108 11 11 0
POLR2D POLR2D O15514 DNA-directed RNA polymerase II subunit RPB4 chr2 Not Cancer Driver No 4 intact, hippie, biogrid 13 54 2 2 0
POLR2E POLR2E P19388 DNA-directed RNA polymerases I, II, and III subunit RPABC1 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 31 36 3 3 0
POLR2F_ENST00000442738 POLR2F P61218 DNA-directed RNA polymerases I, II, and III subunit RPABC2 chr22 Not Cancer Driver No 3 hippie, biogrid 22 57 13 13 0
POLR2G POLR2G P62487 DNA-directed RNA polymerase II subunit RPB7 chr11 Not Cancer Driver No 6 intact, hippie, biogrid 15 15 1 1 0
POLR2H_ENST00000456318 POLR2H P52434 DNA-directed RNA polymerases I, II, and III subunit RPABC3 chr3 Not Cancer Driver No 2 intact, hippie, biogrid 16 14 1 1 0
POLR2I POLR2I P36954 DNA-directed RNA polymerase II subunit RPB9 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 21 22 5 5 0
POLR2J POLR2J P52435 DNA-directed RNA polymerase II subunit RPB11-a chr7 Not Cancer Driver No 3 intact, hippie, biogrid 12 0 0 0 0
POLR2J3 POLR2J3 Q9H1A7 DNA-directed RNA polymerase II subunit RPB11-b2 chr7 Not Cancer Driver No 1 hippie, biogrid 3 0 0 0 0
POLR2K POLR2K P53803 DNA-directed RNA polymerases I, II, and III subunit RPABC4 chr8 Not Cancer Driver No 1 hippie, biogrid 10 11 1 1 0
POLR2L POLR2L P62875 DNA-directed RNA polymerases I, II, and III subunit RPABC5 chr11 Not Cancer Driver No 2 hippie, biogrid 10 0 0 0 0
POLR2M_ENST00000464277 POLR2M Q6EEV4 DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5 chr15 Not Cancer Driver No 4 intact, hippie, biogrid 4 121 4 4 0
POLR3A POLR3A O14802 DNA-directed RNA polymerase III subunit RPC1 chr10 Not Cancer Driver No 2 hippie, biogrid 155 113 17 17 15
POLR3B POLR3B Q9NW08 DNA-directed RNA polymerase III subunit RPC2 chr12 Not Cancer Driver No 2 hippie, biogrid 164 117 20 20 8
POLR3D POLR3D P05423 DNA-directed RNA polymerase III subunit RPC4 chr8 Not Cancer Driver No 1 hippie, biogrid 33 303 24 24 0
POLR3E POLR3E Q9NVU0 DNA-directed RNA polymerase III subunit RPC5 chr16 Not Cancer Driver No 2 hippie, biogrid 84 308 40 40 0
POLR3H_ENST00000396504 POLR3H Q9Y535 DNA-directed RNA polymerase III subunit RPC8 chr22 Not Cancer Driver No 1 hippie, biogrid 23 33 6 6 0
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 Not Cancer Driver No 1 hippie, biogrid 38 27 6 6 0
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 Not Cancer Driver No 3 hippie, biogrid 26 23 4 4 0
PRPF31 PRPF31 Q8WWY3 U4/U6 small nuclear ribonucleoprotein Prp31 chr19 Not Cancer Driver No 1 hippie, biogrid 58 213 17 17 2
RAMP1 RAMP1 O60894 Receptor activity-modifying protein 1 chr2 Not Cancer Driver No 1 hippie, biogrid 16 0 0 0 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RECQL5 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 Not Cancer Driver No 1 hippie, biogrid 132 495 71 71 0
RFC4_ENST00000296273 RFC4 P35249 Replication factor C subunit 4 chr3 Not Cancer Driver No 1 hippie, biogrid 58 50 8 8 0
RNGTT RNGTT O60942 mRNA-capping enzyme chr6 Not Cancer Driver No 2 hippie, biogrid 69 112 12 12 0
RPAP3 RPAP3 Q9H6T3 RNA polymerase II-associated protein 3 chr12 Not Cancer Driver No 2 hippie, biogrid 59 334 37 37 0
RPRD1A RPRD1A Q96P16 Regulation of nuclear pre-mRNA domain-containing protein 1A chr18 Not Cancer Driver No 2 intact, hippie, biogrid 49 86 16 16 0
RPRD1B RPRD1B Q9NQG5 Regulation of nuclear pre-mRNA domain-containing protein 1B chr20 Not Cancer Driver No 5 intact, hippie, biogrid 34 155 16 16 0
RPRD2 RPRD2 Q5VT52 Regulation of nuclear pre-mRNA domain-containing protein 2 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 184 1225 156 156 0
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 Census, Compendium Yes 1 hippie 81 360 58 58 2
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 Not Cancer Driver No 2 hippie, biogrid 62 100 13 13 0
RXRG RXRG P48443 Retinoic acid receptor RXR-gamma chr1 Not Cancer Driver No 1 hippie, biogrid 103 161 41 41 0
SCAF1 SCAF1 Q9H7N4 Splicing factor, arginine/serine-rich 19 chr19 Not Cancer Driver No 1 hippie, biogrid 135 1307 134 134 0
SCAF4 SCAF4 O95104 SR-related and CTD-associated factor 4 chr21 Not Cancer Driver No 1 hippie, biogrid 162 938 132 132 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 Not Cancer Driver No 1 hippie 33 164 12 12 0
SPRR1B SPRR1B P22528 Cornifin-B chr1 Not Cancer Driver No 1 intact, hippie, biogrid 24 73 20 20 0
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 Not Cancer Driver No 1 hippie, biogrid 54 267 32 32 30
SUPT6H SUPT6H Q7KZ85 Transcription elongation factor SPT6 chr17 Not Cancer Driver No 1 hippie, biogrid 222 761 107 107 0
SYDE1 SYDE1 Q6ZW31 Rho GTPase-activating protein SYDE1 chr19 Not Cancer Driver No 2 hippie, biogrid 62 412 27 27 0
TCP1 TCP1 P17987 T-complex protein 1 subunit alpha chr6 Not Cancer Driver No 1 hippie, biogrid 54 55 10 10 0
TJP2_ENST00000377245 TJP2 Q9UDY2 Tight junction protein ZO-2 chr9 Not Cancer Driver No 1 hippie, biogrid 149 919 113 113 1
TNFAIP6 TNFAIP6 P98066 Tumor necrosis factor-inducible gene 6 protein chr2 Not Cancer Driver No 1 hippie, biogrid 62 13 5 5 0
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 43 316 36 36 0
TOPBP1 TOPBP1 Q92547 DNA topoisomerase 2-binding protein 1 chr3 Not Cancer Driver No 1 hippie, biogrid 169 577 59 59 0
URI1 URI1 O94763 Unconventional prefoldin RPB5 interactor 1 chr19 Not Cancer Driver No 3 hippie, biogrid 88 388 64 64 0
UXT_ENST00000333119 UXT Q9UBK9 Protein UXT chrX Not Cancer Driver No 4 intact, hippie, biogrid 21 17 1 1 0
VIM_ENST00000224237 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 hippie, biogrid 84 316 57 57 1
WWP1 WWP1 Q9H0M0 NEDD4-like E3 ubiquitin-protein ligase WWP1 chr8 Not Cancer Driver No 1 hippie, biogrid 139 431 75 75 0
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 2 hippie, biogrid 112 422 57 57 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
YBX1 YBX1 P67809 Y-box-binding protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 41 312 41 41 0
ZFC3H1 ZFC3H1 O60293 Zinc finger C3H1 domain-containing protein chr12 Not Cancer Driver No 2 hippie, biogrid 210 1025 115 115 0
ZNHIT2 ZNHIT2 Q9UHR6 Zinc finger HIT domain-containing protein 2 chr11 Not Cancer Driver No 1 hippie 29 157 15 15 0