Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A2ML1 | A2ML1 | A8K2U0 | Alpha-2-macroglobulin-like protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 269 | 97 | 22 | 22 | 0 |
| ACP7 | ACP7 | Q6ZNF0 | Acid phosphatase type 7 | chr19 | Not Cancer Driver | No | 1 | hippie | 72 | 22 | 7 | 7 | 0 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | Census, Compendium | Yes | 1 | hippie | 108 | 158 | 24 | 24 | 4 |
| ALOX12B | ALOX12B | O75342 | Arachidonate 12-lipoxygenase, 12R-type | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 101 | 16 | 3 | 3 | 18 |
| ANXA8L1 | ANXA8L1 | Q5VT79 | Annexin A8-like protein 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 5 | 37 | 0 | 0 | 0 |
| APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | Not Cancer Driver | No | 1 | hippie | 128 | 418 | 71 | 71 | 17 |
| ATN1_ENST00000396684 | ATN1 | P54259 | Atrophin-1 | chr12 | Not Cancer Driver | No | 1 | hippie | 141 | 1176 | 139 | 139 | 6 |
| ATP12A_ENST00000381946 | ATP12A | P54707 | Potassium-transporting ATPase alpha chain 2 | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 203 | 117 | 24 | 24 | 0 |
| BAG6 | BAG6 | P46379 | Large proline-rich protein BAG6 | chr6 | Not Cancer Driver | No | 1 | hippie | 98 | 861 | 79 | 79 | 0 |
| BIRC2 | BIRC2 | Q13490 | Baculoviral IAP repeat-containing protein 2 | chr11 | Not Cancer Driver | No | 1 | hippie | 69 | 83 | 9 | 9 | 0 |
| CALML3 | CALML3 | P27482 | Calmodulin-like protein 3 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 105 | 28 | 28 | 0 |
| CALML5 | CALML5 | Q9NZT1 | Calmodulin-like protein 5 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 98 | 21 | 21 | 0 |
| CDK10 | CDK10 | Q15131 | Cyclin-dependent kinase 10 | chr16 | Not Cancer Driver | No | 1 | hippie | 42 | 30 | 4 | 4 | 0 |
| CHI3L2 | CHI3L2 | Q15782 | Chitinase-3-like protein 2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 20 | 4 | 4 | 0 |
| CRYBG1 | CRYBG1 | Q9Y4K1 | Beta/gamma crystallin domain-containing protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 211 | 1006 | 124 | 124 | 0 |
| CST3_ENST00000376925 | CST3 | P01034 | Cystatin-C | chr20 | Not Cancer Driver | No | 1 | hippie | 17 | 31 | 1 | 1 | 2 |
| CTSV | CTSV | O60911 | Cathepsin L2 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 55 | 7 | 1 | 1 | 0 |
| DAZAP2_ENST00000412716 | DAZAP2 | Q15038 | DAZ-associated protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 17 | 68 | 7 | 7 | 0 |
| DDX39A | DDX39A | O00148 | ATP-dependent RNA helicase DDX39A | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 44 | 37 | 2 | 2 | 0 |
| DNAJB2 | DNAJB2 | P25686 | DnaJ homolog subfamily B member 2 | chr2 | Not Cancer Driver | No | 2 | hippie, biogrid | 51 | 239 | 40 | 40 | 1 |
| DOCK4 | DOCK4 | Q8N1I0 | Dedicator of cytokinesis protein 4 | chr7 | Not Cancer Driver | No | 1 | hippie | 331 | 397 | 80 | 80 | 0 |
| DSG3 | DSG3 | P32926 | Desmoglein-3 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 270 | 264 | 64 | 64 | 0 |
| EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | Census, Compendium | Yes | 1 | hippie | 444 | 223 | 35 | 35 | 1 |
| ELAVL1 | ELAVL1 | Q15717 | ELAV-like protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 69 | 43 | 5 | 5 | 0 |
| EVPL_ENST00000301607 | EVPL | Q92817 | Envoplakin | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 290 | 1222 | 169 | 169 | 0 |
| FAM189A2 | FAM189A2 | Q15884 | Protein FAM189A2 | chr9 | Not Cancer Driver | No | 1 | intact, hippie | 62 | 231 | 29 | 29 | 0 |
| FBXW11 | FBXW11 | Q9UKB1 | F-box/WD repeat-containing protein 11 | chr5 | Not Cancer Driver | No | 1 | hippie | 75 | 20 | 3 | 3 | 7 |
| FCHSD1 | FCHSD1 | Q86WN1 | F-BAR and double SH3 domains protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 78 | 434 | 50 | 50 | 0 |
| FOLR3 | FOLR3 | P41439 | Folate receptor gamma | chr11 | Not Cancer Driver | No | 1 | hippie | 58 | 15 | 4 | 4 | 0 |
| GABRD | GABRD | O14764 | Gamma-aminobutyric acid receptor subunit delta | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 71 | 19 | 5 | 5 | 1 |
| GLUL_ENST00000331872 | GLUL | P15104 | Glutamine synthetase | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 66 | 104 | 21 | 21 | 2 |
| GSDMA | GSDMA | Q96QA5 | Gasdermin-A | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 87 | 15 | 15 | 0 |
| HAL | HAL | P42357 | Histidine ammonia-lyase | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 98 | 34 | 6 | 6 | 4 |
| HERC2 | HERC2 | O95714 | E3 ubiquitin-protein ligase HERC2 | chr15 | Compendium | Yes | 2 | intact, hippie, biogrid | 718 | 971 | 150 | 150 | 1 |
| HLA-DRA | HLA-DRA | P01903 | HLA class II histocompatibility antigen, DR alpha chain | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 12 | 1 | 1 | 0 |
| HMGCS1_ENST00000433297 | HMGCS1 | Q01581 | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 74 | 10 | 10 | 0 |
| HMOX1 | HMOX1 | P09601 | Heme oxygenase 1 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 81 | 13 | 13 | 0 |
| HRAS | HRAS | P01112 | GTPase HRas | chr11 | Census, Compendium | Yes | 1 | hippie | 107 | 16 | 4 | 4 | 18 |
| IL1RN_ENST00000409930 | IL1RN | P18510 | Interleukin-1 receptor antagonist protein | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 17 | 7 | 7 | 0 |
| IL36G | IL36G | Q9NZH8 | Interleukin-36 gamma | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 23 | 5 | 5 | 0 |
| IL36RN_ENST00000346807 | IL36RN | Q9UBH0 | Interleukin-36 receptor antagonist protein | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 7 | 4 | 4 | 4 |
| IVL | IVL | P07476 | Involucrin | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 115 | 585 | 115 | 115 | 0 |
| KDELR1 | KDELR1 | P24390 | ER lumen protein-retaining receptor 1 | chr19 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 32 | 0 | 0 | 0 | 0 |
| KLK6 | KLK6 | Q92876 | Kallikrein-6 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 62 | 28 | 12 | 12 | 0 |
| LCN2_ENST00000277480 | LCN2 | P80188 | Neutrophil gelatinase-associated lipocalin | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 4 | 3 | 3 | 0 |
| LGALS7B | LGALS7B | P47929 | Galectin-7 | chr19 | Not Cancer Driver | No | 1 | biogrid | 14 | 54 | 5 | 5 | 0 |
| LMBR1L | LMBR1L | Q6UX01 | Protein LMBR1L | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 4 | 0 | 0 | 0 |
| MAP1LC3B | MAP1LC3B | Q9GZQ8 | Microtubule-associated proteins 1A/1B light chain 3B | chr16 | Not Cancer Driver | No | 1 | intact | 10 | 17 | 1 | 1 | 0 |
| MAVS | MAVS | Q7Z434 | Mitochondrial antiviral-signaling protein | chr20 | Not Cancer Driver | No | 1 | hippie | 70 | 411 | 58 | 58 | 0 |
| MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | Census, Compendium | Yes | 1 | intact | 56 | 297 | 37 | 37 | 0 |
| MDM4 | MDM4 | O15151 | Protein Mdm4 | chr1 | Census, Compendium | Yes | 1 | intact, hippie | 57 | 202 | 26 | 26 | 1 |
| MFAP4_ENST00000299610 | MFAP4 | P55083 | Microfibril-associated glycoprotein 4 | chr17 | Not Cancer Driver | No | 1 | hippie | 35 | 0 | 0 | 0 | 0 |
| MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
| NAGK_ENST00000244204 | NAGK | Q9UJ70 | N-acetyl-D-glucosamine kinase | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 5 | 1 | 1 | 0 |
| NDRG2 | NDRG2 | Q9UN36 | Protein NDRG2 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 45 | 111 | 8 | 8 | 0 |
| NFKBIA | NFKBIA | P25963 | NF-kappa-B inhibitor alpha | chr14 | Compendium | Yes | 1 | hippie | 37 | 102 | 9 | 9 | 1 |
| NRSN1 | NRSN1 | Q8IZ57 | Neurensin-1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 17 | 9 | 9 | 0 |
| NT5C3A | NT5C3A | Q9H0P0 | Cytosolic 5'-nucleotidase 3A | chr7 | Compendium | Yes | 1 | hippie, biogrid | 44 | 0 | 0 | 0 | 8 |
| PAPSS2_ENST00000361175 | PAPSS2 | O95340 | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 100 | 7 | 7 | 4 |
| PFDN5 | PFDN5 | Q99471 | Prefoldin subunit 5 | chr12 | Not Cancer Driver | No | 1 | hippie | 18 | 3 | 0 | 0 | 0 |
| PLA2G4D | PLA2G4D | Q86XP0 | Cytosolic phospholipase A2 delta | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 115 | 172 | 17 | 17 | 0 |
| PPL | PPL | O60437 | Periplakin | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 219 | 1133 | 133 | 133 | 0 |
| PSEN2 | PSEN2 | P49810 | Presenilin-2 | chr1 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 68 | 89 | 16 | 16 | 7 |
| RAB7A | RAB7A | P51149 | Ras-related protein Rab-7a | chr3 | Not Cancer Driver | No | 1 | hippie | 27 | 11 | 0 | 0 | 4 |
| RAD23A | RAD23A | P54725 | UV excision repair protein RAD23 homolog A | chr19 | Not Cancer Driver | No | 1 | hippie | 50 | 283 | 41 | 41 | 0 |
| RAD51_ENST00000267868 | RAD51 | Q06609 | DNA repair protein RAD51 homolog 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 42 | 47 | 5 | 5 | 3 |
| RBCK1 | RBCK1 | Q9BYM8 | RanBP-type and C3HC4-type zinc finger-containing protein 1 | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 52 | 140 | 14 | 14 | 2 |
| RGS9BP | RGS9BP | Q6ZS82 | Regulator of G-protein signaling 9-binding protein | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 22 | 1 | 1 | 0 |
| RNF115 | RNF115 | Q9Y4L5 | E3 ubiquitin-protein ligase RNF115 | chr1 | Not Cancer Driver | No | 1 | hippie | 30 | 136 | 14 | 14 | 0 |
| RPL18A | RPL18A | Q02543 | 60S ribosomal protein L18a | chr19 | Not Cancer Driver | No | 1 | hippie | 28 | 25 | 4 | 4 | 0 |
| S100A7A_ENST00000329256 | S100A7A | Q86SG5 | Protein S100-A7A | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 20 | 12 | 12 | 0 |
| SCN1B_ENST00000262631 | SCN1B | Q07699 | Sodium channel subunit beta-1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 4 | 1 | 1 | 5 |
| SERPINA3_ENST00000393080 | SERPINA3 | P01011 | Alpha-1-antichymotrypsin | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 117 | 18 | 10 | 10 | 0 |
| SERPINA9_ENST00000380365 | SERPINA9 | Q86WD7 | Serpin A9 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 96 | 25 | 6 | 6 | 0 |
| SERPINB13_ENST00000344731 | SERPINB13 | Q9UIV8 | Serpin B13 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 84 | 55 | 16 | 16 | 0 |
| SERPINB2_ENST00000299502 | SERPINB2 | P05120 | Plasminogen activator inhibitor 2 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 100 | 29 | 7 | 7 | 0 |
| SERPINB3 | SERPINB3 | P29508 | Serpin B3 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 142 | 47 | 28 | 28 | 0 |
| SERPINB4 | SERPINB4 | P48594 | Serpin B4 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 120 | 48 | 18 | 18 | 0 |
| SERPINB7 | SERPINB7 | O75635 | Serpin B7 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 100 | 30 | 8 | 8 | 0 |
| SFN | SFN | P31947 | 14-3-3 protein sigma | chr1 | Not Cancer Driver | No | 1 | hippie | 27 | 75 | 9 | 9 | 0 |
| SLC10A7_ENST00000335472 | SLC10A7 | Q0GE19 | Sodium/bile acid cotransporter 7 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 0 | 0 | 0 | 3 |
| SLC17A2_ENST00000265425 | SLC17A2 | O00624 | Sodium-dependent phosphate transport protein 3 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 12 | 5 | 5 | 0 |
| STAT3 | STAT3 | P40763 | Signal transducer and activator of transcription 3 | chr17 | Census, Compendium | Yes | 1 | hippie, biogrid | 110 | 152 | 15 | 15 | 19 |
| SUFU | SUFU | Q9UMX1 | Suppressor of fused homolog | chr10 | Census | Yes | 1 | intact | 55 | 199 | 19 | 19 | 2 |
| SULT2B1 | SULT2B1 | O00204 | Sulfotransferase 2B1 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 100 | 11 | 11 | 0 |
| TANK | TANK | Q92844 | TRAF family member-associated NF-kappa-B activator | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 42 | 302 | 26 | 26 | 0 |
| TAX1BP1 | TAX1BP1 | Q86VP1 | Tax1-binding protein 1 | chr7 | Not Cancer Driver | No | 2 | hippie, biogrid | 78 | 429 | 50 | 50 | 0 |
| TGM1 | TGM1 | P22735 | Protein-glutamine gamma-glutamyltransferase K | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 118 | 230 | 37 | 37 | 65 |
| TMEM40_ENST00000264728 | TMEM40 | Q8WWA1 | Transmembrane protein 40 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 150 | 23 | 23 | 0 |
| TNIP1_ENST00000522226 | TNIP1 | Q15025 | TNFAIP3-interacting protein 1 | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 85 | 625 | 83 | 83 | 0 |
| TRADD | TRADD | Q15628 | Tumor necrosis factor receptor type 1-associated DEATH domain protein | chr16 | Not Cancer Driver | No | 1 | intact, hippie | 26 | 74 | 5 | 5 | 0 |
| TTR | TTR | P02766 | Transthyretin | chr18 | Not Cancer Driver | No | 1 | hippie | 28 | 25 | 8 | 8 | 75 |
| TYMP_ENST00000395680 | TYMP | P19971 | Thymidine phosphorylase | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 143 | 7 | 7 | 5 |
| UBA52_ENST00000595683 | UBA52 | P62987 | Ubiquitin-60S ribosomal protein L40 | chr19 | Not Cancer Driver | No | 1 | hippie | 19 | 45 | 8 | 8 | 0 |
| UBE2D1 | UBE2D1 | P51668 | Ubiquitin-conjugating enzyme E2 D1 | chr10 | Not Cancer Driver | No | 1 | hippie | 13 | 14 | 0 | 0 | 0 |
| UBE2D2 | UBE2D2 | P62837 | Ubiquitin-conjugating enzyme E2 D2 | chr5 | Compendium | Yes | 1 | hippie | 19 | 13 | 1 | 1 | 0 |
| UBE2D3_ENST00000394801 | UBE2D3 | P61077 | Ubiquitin-conjugating enzyme E2 D3 | chr4 | Not Cancer Driver | No | 1 | hippie | 21 | 13 | 4 | 4 | 0 |
| UBE2D4 | UBE2D4 | Q9Y2X8 | Ubiquitin-conjugating enzyme E2 D4 | chr7 | Not Cancer Driver | No | 1 | hippie | 13 | 21 | 1 | 1 | 0 |
| UBE2E1 | UBE2E1 | P51965 | Ubiquitin-conjugating enzyme E2 E1 | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 21 | 78 | 10 | 10 | 0 |
| UBE2E2_ENST00000425792 | UBE2E2 | Q96LR5 | Ubiquitin-conjugating enzyme E2 E2 | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 28 | 90 | 15 | 15 | 0 |
| UBE2E3_ENST00000602710 | UBE2E3 | Q969T4 | Ubiquitin-conjugating enzyme E2 E3 | chr2 | Not Cancer Driver | No | 2 | intact, hippie | 34 | 97 | 14 | 14 | 0 |
| UBE2I | UBE2I | P63279 | SUMO-conjugating enzyme UBC9 | chr16 | Not Cancer Driver | No | 1 | hippie | 16 | 16 | 3 | 3 | 0 |
| UBE2N | UBE2N | P61088 | Ubiquitin-conjugating enzyme E2 N | chr12 | Not Cancer Driver | No | 1 | hippie | 25 | 24 | 3 | 3 | 0 |
| UBE2W_ENST00000602593 | UBE2W | Q96B02 | Ubiquitin-conjugating enzyme E2 W | chr8 | Not Cancer Driver | No | 2 | hippie, biogrid | 19 | 26 | 5 | 5 | 0 |
| USP9X_ENST00000378308 | USP9X | Q93008 | Probable ubiquitin carboxyl-terminal hydrolase FAF-X | chrX | Census, Compendium | Yes | 1 | hippie | 339 | 405 | 51 | 51 | 1 |
| VCP | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | Not Cancer Driver | No | 2 | intact, hippie | 88 | 186 | 16 | 16 | 16 |
| YWHAB_ENST00000353703 | YWHAB | P31946 | 14-3-3 protein beta/alpha | chr20 | Not Cancer Driver | No | 1 | hippie | 22 | 109 | 4 | 4 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|