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RGS2 ,RGS2 ,P41220
  • Uniprot Accession= P41220
  • Ensembl Transcript= ENST00000235382.6
  • Uniprot Name= RGS2
  • Name= Regulator of G-protein signaling 2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 1
  • Number of Interaction partner in biogrid: 23
  • Number of Interaction partner in hippie: 76
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ADCY5 ADCY5 O95622 Adenylate cyclase type 5 chr3 Not Cancer Driver No 1 hippie 234 268 23 23 2
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 Not Cancer Driver No 1 hippie 130 40 8 8 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 Not Cancer Driver No 1 hippie 52 35 4 4 0
ARFGAP1_ENST00000370283 ARFGAP1 Q8N6T3 ADP-ribosylation factor GTPase-activating protein 1 chr20 Not Cancer Driver No 1 hippie, biogrid 60 264 37 37 0
BBS10 BBS10 Q8TAM1 Bardet-Biedl syndrome 10 protein chr12 Not Cancer Driver No 1 hippie 78 67 11 11 24
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 Not Cancer Driver No 1 hippie 19 115 15 15 7
CEP126 CEP126 Q9P2H0 Centrosomal protein of 126 kDa chr11 Not Cancer Driver No 1 hippie 197 840 151 151 0
CHD3_ENST00000330494 CHD3 Q12873 Chromodomain-helicase-DNA-binding protein 3 chr17 Not Cancer Driver No 1 hippie 235 1015 122 122 18
CIAO1 CIAO1 O76071 Probable cytosolic iron-sulfur protein assembly protein CIAO1 chr2 Not Cancer Driver No 1 hippie 30 20 2 2 0
CLTA CLTA P09496 Clathrin light chain A chr9 Not Cancer Driver No 1 hippie 20 192 12 12 0
COMT COMT P21964 Catechol O-methyltransferase chr22 Not Cancer Driver No 1 hippie 21 5 0 0 0
COPB1_ENST00000439561 COPB1 P53618 Coatomer subunit beta chr11 Not Cancer Driver No 1 hippie 110 95 10 10 1
COPB2 COPB2 P35606 Coatomer subunit beta' chr3 Not Cancer Driver No 1 hippie 111 114 22 22 0
CRMP1_ENST00000397890 CRMP1 Q14194 Dihydropyrimidinase-related protein 1 chr4 Not Cancer Driver No 1 hippie 122 96 15 15 0
CTSB CTSB P07858 Cathepsin B chr8 Not Cancer Driver No 1 hippie 41 7 2 2 0
CUL4B CUL4B Q13620 Cullin-4B chrX Not Cancer Driver No 1 hippie 138 207 38 38 2
DDR1_ENST00000324771 DDR1 Q08345 Epithelial discoidin domain-containing receptor 1 chr6 Not Cancer Driver No 1 hippie, biogrid 123 253 49 49 0
DUSP21 DUSP21 Q9H596 Dual specificity protein phosphatase 21 chrX Not Cancer Driver No 1 hippie 49 0 0 0 0
DYNLL1_ENST00000242577 DYNLL1 P63167 Dynein light chain 1, cytoplasmic chr12 Not Cancer Driver No 1 hippie, biogrid 9 0 0 0 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EIF3E EIF3E P60228 Eukaryotic translation initiation factor 3 subunit E chr8 Census, Compendium Yes 1 hippie 73 27 1 1 0
EIF3L EIF3L Q9Y262 Eukaryotic translation initiation factor 3 subunit L chr22 Not Cancer Driver No 1 hippie 60 41 1 1 0
EPHX1_ENST00000366837 EPHX1 P07099 Epoxide hydrolase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 75 7 3 3 0
FBXO44_ENST00000251547 FBXO44 Q9H4M3 F-box only protein 44 chr1 Not Cancer Driver No 1 hippie 30 27 3 3 0
FZD5 FZD5 Q13467 Frizzled-5 chr2 Not Cancer Driver No 1 hippie 45 58 4 4 0
GDE1 GDE1 Q9NZC3 Glycerophosphodiester phosphodiesterase 1 chr16 Not Cancer Driver No 1 hippie 36 37 1 1 0
GIT1_ENST00000225394 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 Not Cancer Driver No 1 hippie, biogrid 67 434 42 42 0
GNA15 GNA15 P30679 Guanine nucleotide-binding protein subunit alpha-15 chr19 Not Cancer Driver No 1 hippie 51 15 6 6 0
GNAI3 GNAI3 P08754 Guanine nucleotide-binding protein G(i) subunit alpha-3 chr1 Not Cancer Driver No 1 hippie 42 11 0 0 1
GNAQ GNAQ P50148 Guanine nucleotide-binding protein G(q) subunit alpha chr9 Census, Compendium Yes 1 hippie 57 14 1 1 1
GNAS_ENST00000371075 GNAS O95467 Neuroendocrine secretory protein 55 chr20 Census, Compendium Yes 1 hippie 71 221 65 65 0
HAUS5 HAUS5 O94927 HAUS augmin-like complex subunit 5 chr19 Not Cancer Driver No 1 hippie 78 182 20 20 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 Not Cancer Driver No 1 hippie, biogrid 149 251 52 52 0
IBTK IBTK Q9P2D0 Inhibitor of Bruton tyrosine kinase chr6 Not Cancer Driver No 1 hippie 146 364 39 39 0
IER3IP1 IER3IP1 Q9Y5U9 Immediate early response 3-interacting protein 1 chr18 Not Cancer Driver No 1 hippie 3 0 0 0 2
KBTBD7 KBTBD7 Q8WVZ9 Kelch repeat and BTB domain-containing protein 7 chr13 Not Cancer Driver No 2 hippie, biogrid 92 105 6 6 0
KLK8_ENST00000600767 KLK8 O60259 Kallikrein-8 chr19 Not Cancer Driver No 1 hippie 65 76 15 15 0
LIG1 LIG1 P18858 DNA ligase 1 chr19 Not Cancer Driver No 1 hippie 137 397 62 62 0
LRFN1 LRFN1 Q9P244 Leucine-rich repeat and fibronectin type III domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 96 278 37 37 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 519 90 17 17 23
MARCH6 MARCHF6 O60337 E3 ubiquitin-protein ligase MARCHF6 chr5 Not Cancer Driver No 1 intact 114 114 13 13 0
MB_ENST00000397328 MB P02144 Myoglobin chr22 Not Cancer Driver No 1 hippie, biogrid 13 38 4 4 0
METAP2 METAP2 P50579 Methionine aminopeptidase 2 chr12 Not Cancer Driver No 2 hippie, biogrid 54 176 19 19 0
METTL18 METTL18 O95568 Histidine protein methyltransferase 1 homolog chr1 Not Cancer Driver No 1 hippie 37 125 8 8 0
MIPOL1 MIPOL1 Q8TD10 Mirror-image polydactyly gene 1 protein chr14 Not Cancer Driver No 2 hippie, biogrid 58 273 37 37 0
MON1A MON1A Q86VX9 Vacuolar fusion protein MON1 homolog A chr3 Not Cancer Driver No 1 hippie 54 260 14 14 0
MTUS2 MTUS2 Q5JR59 Microtubule-associated tumor suppressor candidate 2 chr13 Not Cancer Driver No 1 hippie 370 1208 329 329 0
NINL NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 3 hippie, biogrid 230 881 150 150 0
NIPSNAP1 NIPSNAP1 Q9BPW8 Protein NipSnap homolog 1 chr22 Not Cancer Driver No 1 hippie, biogrid 31 9 0 0 0
NISCH_ENST00000479054 NISCH Q9Y2I1 Nischarin chr3 Not Cancer Driver No 1 hippie, biogrid 160 418 43 43 0
PPP1R9A_ENST00000433881 PPP1R9A Q9ULJ8 Neurabin-1 chr7 Not Cancer Driver No 1 hippie 217 887 174 174 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 Not Cancer Driver No 1 hippie 94 154 22 22 0
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 Census, Compendium Yes 1 hippie 205 148 40 40 0
PRKCG PRKCG P05129 Protein kinase C gamma type chr19 Not Cancer Driver No 1 hippie 172 151 43 43 5
PRKCSH_ENST00000589838 PRKCSH P14314 Glucosidase 2 subunit beta chr19 Not Cancer Driver No 1 hippie, biogrid 68 320 41 41 0
PRKG1_ENST00000401604 PRKG1 Q13976 cGMP-dependent protein kinase 1 chr10 Not Cancer Driver No 1 hippie 167 93 22 22 1
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 Not Cancer Driver No 1 hippie 110 78 15 15 31
PTPN13_ENST00000411767 PTPN13 Q12923 Tyrosine-protein phosphatase non-receptor type 13 chr4 Census, Compendium Yes 2 hippie, biogrid 299 1231 149 149 0
RAB2A RAB2A P61019 Ras-related protein Rab-2A chr8 Not Cancer Driver No 1 hippie 22 58 4 4 0
RABAC1 RABAC1 Q9UI14 Prenylated Rab acceptor protein 1 chr19 Not Cancer Driver No 1 hippie 23 13 2 2 0
RAP1B_ENST00000393436 RAP1B P61224 Ras-related protein Rap-1b chr12 Not Cancer Driver No 1 hippie 26 14 3 3 0
REEP5 REEP5 Q00765 Receptor expression-enhancing protein 5 chr5 Not Cancer Driver No 1 hippie 34 0 0 0 0
RIN3 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 hippie 137 417 61 61 0
SCN5A_ENST00000333535 SCN5A Q14524 Sodium channel protein type 5 subunit alpha chr3 Not Cancer Driver No 1 hippie 491 550 144 144 190
SERPINA10 SERPINA10 Q9UK55 Protein Z-dependent protease inhibitor chr14 Not Cancer Driver No 2 hippie, biogrid 108 74 18 18 0
STK26 STK26 Q9P289 Serine/threonine-protein kinase 26 chrX Not Cancer Driver No 2 hippie, biogrid 62 119 18 18 0
STRIP1 STRIP1 Q5VSL9 Striatin-interacting protein 1 chr1 Not Cancer Driver No 2 hippie, biogrid 97 267 33 33 0
STXBP4 STXBP4 Q6ZWJ1 Syntaxin-binding protein 4 chr17 Not Cancer Driver No 2 hippie, biogrid 78 211 24 24 0
TAF2 TAF2 Q6P1X5 Transcription initiation factor TFIID subunit 2 chr8 Not Cancer Driver No 1 hippie, biogrid 129 241 34 34 1
TSPAN15 TSPAN15 O95858 Tetraspanin-15 chr10 Not Cancer Driver No 1 hippie 29 0 0 0 0
TUBB2B TUBB2B Q9BVA1 Tubulin beta-2B chain chr6 Not Cancer Driver No 1 hippie 43 68 10 10 10
VPS29_ENST00000549578 VPS29 Q9UBQ0 Vacuolar protein sorting-associated protein 29 chr12 Not Cancer Driver No 1 hippie, biogrid 24 0 0 0 0
WDR74_ENST00000278856 WDR74 Q6RFH5 WD repeat-containing protein 74 chr11 Not Cancer Driver No 1 hippie, biogrid 44 177 21 21 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 Not Cancer Driver No 1 hippie 66 140 12 12 0
ZBTB48 ZBTB48 P10074 Telomere zinc finger-associated protein chr1 Not Cancer Driver No 1 hippie 53 237 16 16 0
ZNF579 ZNF579 Q8NAF0 Zinc finger protein 579 chr19 Not Cancer Driver No 1 hippie 28 447 22 22 0
ZYX ZYX Q15942 Zyxin chr7 Not Cancer Driver No 1 hippie 83 385 52 52 0