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RER1 ,RER1 ,O15258
  • Number of Interaction partner in intact: 16
  • Number of Interaction partner in biogrid: 67
  • Number of Interaction partner in hippie: 103
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACKR2 ACKR2 O00590 Atypical chemokine receptor 2 chr3 Not Cancer Driver No 1 hippie, biogrid 70 25 6 6 0
APOB APOB P04114 Apolipoprotein B-100 chr2 Not Cancer Driver No 1 hippie, biogrid 1022 315 72 72 3
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 intact, hippie 128 418 71 71 17
AQP3 AQP3 Q92482 Aquaporin-3 chr9 Not Cancer Driver No 1 hippie, biogrid 34 12 0 0 0
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 79 239 25 25 1
ATP13A3_ENST00000256031 ATP13A3 Q9H7F0 Polyamine-transporting ATPase 13A3 chr3 Not Cancer Driver No 1 hippie, biogrid 149 49 11 11 0
ATP1A3_ENST00000302102 ATP1A3 P13637 Sodium/potassium-transporting ATPase subunit alpha-3 chr19 Not Cancer Driver No 1 hippie, biogrid 200 115 29 29 31
ATP2A1 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 Not Cancer Driver No 1 hippie, biogrid 157 80 11 11 1
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 Not Cancer Driver No 1 hippie 66 23 5 5 2
ATP5ME ATP5ME P56385 ATP synthase subunit e, mitochondrial chr4 Not Cancer Driver No 1 hippie 6 18 2 2 0
ATP5MG ATP5MG O75964 ATP synthase subunit g, mitochondrial chr11 Not Cancer Driver No 1 hippie 16 0 0 0 0
ATP5PD ATP5PD O75947 ATP synthase subunit d, mitochondrial chr17 Not Cancer Driver No 1 hippie 12 15 0 0 0
ATP5PO ATP5PO P48047 ATP synthase subunit O, mitochondrial chr21 Not Cancer Driver No 1 hippie 19 9 2 2 0
B3GAT1_ENST00000312527 B3GAT1 Q9P2W7 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 chr11 Not Cancer Driver No 1 hippie, biogrid 85 93 32 32 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX Not Cancer Driver No 1 hippie, biogrid 37 104 14 14 0
C5AR1 C5AR1 P21730 C5a anaphylatoxin chemotactic receptor 1 chr19 Not Cancer Driver No 1 hippie, biogrid 71 0 0 0 0
CAV2 CAV2 P51636 Caveolin-2 chr7 Not Cancer Driver No 1 hippie, biogrid 20 5 2 2 0
CCR1 CCR1 P32246 C-C chemokine receptor type 1 chr3 Not Cancer Driver No 1 hippie, biogrid 69 14 5 5 0
CCR6_ENST00000349984 CCR6 P51684 C-C chemokine receptor type 6 chr6 Not Cancer Driver No 1 hippie, biogrid 56 13 2 2 0
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 Census Yes 1 hippie 29 54 9 9 0
CHRNA9 CHRNA9 Q9UGM1 Neuronal acetylcholine receptor subunit alpha-9 chr4 Not Cancer Driver No 1 hippie, biogrid 76 23 6 6 0
CNR2 CNR2 P34972 Cannabinoid receptor 2 chr1 Not Cancer Driver No 1 intact, hippie 57 21 4 4 0
DPEP1 DPEP1 P16444 Dipeptidase 1 chr16 Not Cancer Driver No 2 hippie, biogrid 54 41 6 6 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EMC1 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 1 hippie 107 59 6 6 2
ENDOD1 ENDOD1 O94919 Endonuclease domain-containing 1 protein chr11 Not Cancer Driver No 1 hippie, biogrid 51 72 9 9 0
ERGIC1 ERGIC1 Q969X5 Endoplasmic reticulum-Golgi intermediate compartment protein 1 chr5 Not Cancer Driver No 1 hippie, biogrid 38 26 2 2 0
ERGIC3_ENST00000348547 ERGIC3 Q9Y282 Endoplasmic reticulum-Golgi intermediate compartment protein 3 chr20 Not Cancer Driver No 1 hippie, biogrid 53 23 3 3 0
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
FFAR1 FFAR1 O14842 Free fatty acid receptor 1 chr19 Not Cancer Driver No 1 hippie, biogrid 45 2 0 0 0
FPR2 FPR2 P25090 N-formyl peptide receptor 2 chr19 Not Cancer Driver No 1 hippie, biogrid 96 26 5 5 0
GJD3 GJD3 Q8N144 Gap junction delta-3 protein chr17 Not Cancer Driver No 1 hippie, biogrid 5 79 0 0 0
GPR182 GPR182 O15218 G-protein coupled receptor 182 chr12 Not Cancer Driver No 1 hippie, biogrid 49 33 4 4 0
GPR84 GPR84 Q9NQS5 G-protein coupled receptor 84 chr12 Not Cancer Driver No 1 hippie, biogrid 64 89 14 14 0
HAP1_ENST00000310778 HAP1 P54257 Huntingtin-associated protein 1 chr17 Not Cancer Driver No 1 hippie, biogrid 97 454 60 60 0
HBA1 HBA2 D1MGQ2 Alpha-1-globin chr16 Not Cancer Driver No 1 biogrid 5 4 0 0 0
HBA2 HBA2 P69905 Hemoglobin subunit alpha chr16 Not Cancer Driver No 1 biogrid 9 4 0 0 0
HBB HBB P68871 Hemoglobin subunit beta chr11 Not Cancer Driver No 1 hippie, biogrid 45 7 2 2 5
HERC2 HERC2 O95714 E3 ubiquitin-protein ligase HERC2 chr15 Compendium Yes 1 hippie 718 971 150 150 1
HLA-DPA1 HLA-DPA1 P20036 HLA class II histocompatibility antigen, DP alpha 1 chain chr6 Not Cancer Driver No 1 hippie, biogrid 37 30 4 4 0
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 1 intact, hippie 107 16 4 4 18
HSCB HSCB Q8IWL3 Iron-sulfur cluster co-chaperone protein HscB chr22 Not Cancer Driver No 1 intact, hippie 36 25 6 6 0
HTR1B HTR1B P28222 5-hydroxytryptamine receptor 1B chr6 Not Cancer Driver No 1 hippie, biogrid 91 33 15 15 0
IFITM3 IFITM3 Q01628 Interferon-induced transmembrane protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 69 18 5 5 0
IMMT IMMT Q16891 MICOS complex subunit MIC60 chr2 Not Cancer Driver No 1 hippie, biogrid 97 400 50 50 0
KCNK1 KCNK1 O00180 Potassium channel subfamily K member 1 chr1 Not Cancer Driver No 1 hippie, biogrid 65 21 4 4 0
KRAS KRAS P01116 GTPase KRas chr12 Census, Compendium Yes 1 intact, hippie, biogrid 788 7 2 2 27
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 Not Cancer Driver No 1 hippie, biogrid 47 93 10 10 0
LAMP3 LAMP3 Q9UQV4 Lysosome-associated membrane glycoprotein 3 chr3 Not Cancer Driver No 1 hippie, biogrid 67 222 38 38 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
MFSD4A MFSD4A Q8N468 Major facilitator superfamily domain-containing protein 4A chr1 Not Cancer Driver No 1 hippie 56 29 3 3 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 Not Cancer Driver No 1 hippie 150 711 79 79 0
NIPAL1 NIPAL1 Q6NVV3 Magnesium transporter NIPA3 chr4 Not Cancer Driver No 1 hippie, biogrid 51 2 0 0 0
NPC1 NPC1 O15118 NPC intracellular cholesterol transporter 1 chr18 Not Cancer Driver No 1 hippie 155 24 0 0 150
NRAS NRAS P01111 GTPase NRas chr1 Census, Compendium Yes 1 hippie, biogrid 284 10 0 0 14
NUP155 NUP155 O75694 Nuclear pore complex protein Nup155 chr5 Not Cancer Driver No 1 hippie, biogrid 154 221 19 19 1
P2RY2_ENST00000393596 P2RY2 P41231 P2Y purinoceptor 2 chr11 Not Cancer Driver No 1 hippie, biogrid 67 60 13 13 0
P2RY8 P2RY8 Q86VZ1 P2Y purinoceptor 8 chrX Census, Compendium Yes 1 hippie, biogrid 126 23 5 5 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 Not Cancer Driver No 1 hippie 57 299 30 30 2
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PMP22_ENST00000612492 PMP22 Q01453 Peripheral myelin protein 22 chr17 Not Cancer Driver No 1 hippie 20 0 0 0 37
POMK POMK Q9H5K3 Protein O-mannose kinase chr8 Not Cancer Driver No 1 hippie, biogrid 53 30 9 9 3
PTBP3_ENST00000374255 PTBP3 O95758 Polypyrimidine tract-binding protein 3 chr9 Not Cancer Driver No 1 intact, hippie 61 114 9 9 0
RAB1A RAB1A P62820 Ras-related protein Rab-1A chr2 Not Cancer Driver No 1 hippie, biogrid 16 38 2 2 0
RAB5C_ENST00000393860 RAB5C P51148 Ras-related protein Rab-5C chr17 Not Cancer Driver No 1 hippie, biogrid 24 50 4 4 0
REEP5 REEP5 Q00765 Receptor expression-enhancing protein 5 chr5 Not Cancer Driver No 1 hippie, biogrid 34 0 0 0 0
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 Not Cancer Driver No 1 hippie 26 22 5 5 0
RNF2 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 1 hippie 40 203 22 22 0
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
S1PR1 S1PR1 P21453 Sphingosine 1-phosphate receptor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 86 29 6 6 0
SCAND1_ENST00000305978 SCAND1 P57086 SCAN domain-containing protein 1 chr20 Not Cancer Driver No 1 intact, hippie 11 152 9 9 0
SEC62 SEC62 Q99442 Translocation protein SEC62 chr3 Not Cancer Driver No 1 hippie, biogrid 41 211 23 23 0
SERINC2_ENST00000373709 SERINC2 Q96SA4 Serine incorporator 2 chr1 Not Cancer Driver No 1 hippie, biogrid 49 6 0 0 0
SH3GL3_ENST00000427482 SH3GL3 Q99963 Endophilin-A3 chr15 Not Cancer Driver No 1 hippie, biogrid 88 83 23 23 0
SIGMAR1 SIGMAR1 Q99720 Sigma non-opioid intracellular receptor 1 chr9 Not Cancer Driver No 1 hippie, biogrid 22 2 0 0 1
SLC11A2_ENST00000262051 SLC11A2 P49281 Natural resistance-associated macrophage protein 2 chr12 Not Cancer Driver No 1 hippie, biogrid 60 38 5 5 3
SLC2A12 SLC2A12 Q8TD20 Solute carrier family 2, facilitated glucose transporter member 12 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 87 52 4 4 0
SLC30A2_ENST00000374278 SLC30A2 Q9BRI3 Zinc transporter 2 chr1 Not Cancer Driver No 1 hippie, biogrid 46 42 5 5 2
SLC35F2 SLC35F2 Q8IXU6 Solute carrier family 35 member F2 chr11 Not Cancer Driver No 1 hippie, biogrid 53 12 0 0 0
SLC39A4 SLC39A4 Q6P5W5 Zinc transporter ZIP4 chr8 Not Cancer Driver No 1 hippie, biogrid 77 116 11 11 9
SPPL2B SPPL2B Q8TCT7 Signal peptide peptidase-like 2B chr19 Not Cancer Driver No 1 hippie, biogrid 68 99 17 17 0
STRA6_ENST00000323940 STRA6 Q9BX79 Receptor for retinol uptake STRA6 chr15 Not Cancer Driver No 1 hippie, biogrid 77 84 14 14 6
STX12 STX12 Q86Y82 Syntaxin-12 chr1 Not Cancer Driver No 1 hippie, biogrid 21 156 9 9 0
SYCE3 SYCE3 A1L190 Synaptonemal complex central element protein 3 chr22 Not Cancer Driver No 2 intact, hippie, biogrid 8 40 2 2 0
SYNGR1 SYNGR1 O43759 Synaptogyrin-1 chr22 Not Cancer Driver No 1 hippie, biogrid 26 48 5 5 0
SYT16 SYT16 Q17RD7 Synaptotagmin-16 chr14 Not Cancer Driver No 1 intact, hippie 178 394 113 113 0
SYVN1 SYVN1 Q86TM6 E3 ubiquitin-protein ligase synoviolin chr11 Not Cancer Driver No 1 hippie 63 284 32 32 0
TCTN2 TCTN2 Q96GX1 Tectonic-2 chr12 Not Cancer Driver No 1 intact, hippie 75 23 2 2 0
TCTN3 TCTN3 Q6NUS6 Tectonic-3 chr10 Not Cancer Driver No 1 intact, hippie 45 71 8 8 1
TMEM17 TMEM17 Q86X19 Transmembrane protein 17 chr2 Not Cancer Driver No 1 intact, hippie 22 14 2 2 0
TMEM184A TMEM184A Q6ZMB5 Transmembrane protein 184A chr7 Not Cancer Driver No 1 hippie, biogrid 59 76 17 17 0
TMEM185A TMEM185A Q8NFB2 Transmembrane protein 185A chrX Not Cancer Driver No 1 hippie, biogrid 29 19 0 0 0
TMEM216 TMEM216 Q9P0N5 Transmembrane protein 216 chr11 Not Cancer Driver No 1 intact, hippie 11 0 0 0 7
TMEM72 TMEM72 A0PK05 Transmembrane protein 72 chr10 Not Cancer Driver No 1 hippie, biogrid 51 98 22 22 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TSPAN5 TSPAN5 P62079 Tetraspanin-5 chr4 Not Cancer Driver No 1 hippie, biogrid 49 0 0 0 0
TSPAN8 TSPAN8 P19075 Tetraspanin-8 chr12 Not Cancer Driver No 1 hippie, biogrid 50 0 0 0 0
UBL4A UBL4A P11441 Ubiquitin-like protein 4A chrX Not Cancer Driver No 1 hippie 22 16 5 5 0
UNK UNK Q9C0B0 RING finger protein unkempt homolog chr17 Not Cancer Driver No 1 hippie 79 511 46 46 0
UPK1A_ENST00000222275 UPK1A O00322 Uroplakin-1a chr19 Not Cancer Driver No 1 intact, hippie, biogrid 36 0 0 0 0
VDAC2_ENST00000543351 VDAC2 P45880 Voltage-dependent anion-selective channel protein 2 chr10 Not Cancer Driver No 1 hippie, biogrid 35 9 1 1 0
VIPR1 VIPR1 P32241 Vasoactive intestinal polypeptide receptor 1 chr3 Not Cancer Driver No 1 hippie, biogrid 41 10 2 2 0
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 30 35 3 3 0
WIPF1_ENST00000359761 WIPF1 O43516 WAS/WASL-interacting protein family member 1 chr2 Not Cancer Driver No 1 intact, hippie 110 503 110 110 0