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RCC2 ,RCC2 ,Q9P258
  • Uniprot Accession= Q9P258
  • Ensembl Transcript= ENST00000375436.8
  • Uniprot Name= RCC2
  • Name= Protein RCC2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 30
  • Number of Interaction partner in biogrid: 19
  • Number of Interaction partner in hippie: 131
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 56 28 6 6 0
ACOT7 ACOT7 O00154 Cytosolic acyl coenzyme A thioester hydrolase chr1 Not Cancer Driver No 1 hippie 43 77 16 16 0
ACTC1 ACTC1 P68032 Actin, alpha cardiac muscle 1 chr15 Not Cancer Driver No 1 hippie 114 48 19 19 11
AHCY AHCY P23526 Adenosylhomocysteinase chr20 Not Cancer Driver No 1 hippie, biogrid 58 0 0 0 4
AIM2 AIM2 O14862 Interferon-inducible protein AIM2 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 73 78 22 22 0
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie 196 443 88 88 169
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 Not Cancer Driver No 1 intact, hippie 18 5 0 0 0
ASH2L ASH2L Q9UBL3 Set1/Ash2 histone methyltransferase complex subunit ASH2 chr8 Not Cancer Driver No 1 hippie 95 293 39 39 0
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 Not Cancer Driver No 1 hippie 40 25 6 6 1
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 Not Cancer Driver No 1 hippie 51 63 8 8 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 Not Cancer Driver No 1 intact, hippie 50 150 30 30 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BRD7_ENST00000394688 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 Compendium Yes 1 hippie 82 482 57 57 0
BUD31 BUD31 P41223 Protein BUD31 homolog chr7 Not Cancer Driver No 1 hippie, biogrid 20 32 4 4 0
CCDC8 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie 96 505 91 91 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 Not Cancer Driver No 1 hippie 39 23 2 2 1
CDCA8_ENST00000327331 CDCA8 Q53HL2 Borealin chr1 Not Cancer Driver No 1 hippie 23 170 13 13 0
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 24 0 0 0 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 intact, hippie 287 145 18 18 151
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 Not Cancer Driver No 1 hippie 25 201 22 22 2
CIC CIC Q96RK0 Protein capicua homolog chr19 Census, Compendium Yes 1 hippie 276 1550 266 266 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 Not Cancer Driver No 1 hippie 36 32 7 7 0
COQ2_ENST00000647002 COQ2 Q96H96 4-hydroxybenzoate polyprenyltransferase, mitochondrial chr4 Not Cancer Driver No 1 intact, hippie, biogrid 23 25 0 0 17
CORO1C_ENST00000541050 CORO1C Q9ULV4 Coronin-1C chr12 Not Cancer Driver No 1 hippie 61 84 13 13 0
CUL4B CUL4B Q13620 Cullin-4B chrX Not Cancer Driver No 1 hippie 138 207 38 38 2
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 188 372 41 41 3
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 34 181 23 23 0
DEF6 DEF6 Q9H4E7 Differentially expressed in FDCP 6 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 72 336 30 30 0
DIPK2A DIPK2A Q8NDZ4 Divergent protein kinase domain 2A chr3 Not Cancer Driver No 1 intact, hippie 56 9 0 0 0
DOCK11 DOCK11 Q5JSL3 Dedicator of cytokinesis protein 11 chrX Not Cancer Driver No 1 hippie 312 240 29 29 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 104 284 33 33 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EIF2D EIF2D P41214 Eukaryotic translation initiation factor 2D chr1 Not Cancer Driver No 1 hippie, biogrid 51 143 11 11 0
EIF6_ENST00000374436 EIF6 P56537 Eukaryotic translation initiation factor 6 chr20 Not Cancer Driver No 1 intact, hippie 30 17 3 3 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
EMC4 EMC4 Q5J8M3 ER membrane protein complex subunit 4 chr15 Not Cancer Driver No 1 hippie 15 17 2 2 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
ERG_ENST00000288319 ERG P11308 Transcriptional regulator ERG chr21 Census, Compendium Yes 1 hippie 95 296 54 54 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
ETV3 ETV3 P41162 ETS translocation variant 3 chr1 Not Cancer Driver No 1 intact, hippie 48 330 24 24 0
FAF1 FAF1 Q9UNN5 FAS-associated factor 1 chr1 Not Cancer Driver No 1 hippie 83 241 34 34 0
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 intact, hippie 394 1243 185 185 8
FTSJ1 FTSJ1 Q9UET6 Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase chrX Not Cancer Driver No 1 intact, hippie 44 89 14 14 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 74 184 30 30 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 hippie 85 352 65 65 0
GABARAPL1_ENST00000545887 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 19 10 1 1 0
GDI1 GDI1 P31150 Rab GDP dissociation inhibitor alpha chrX Not Cancer Driver No 1 hippie 69 34 6 6 2
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 intact, hippie 28 10 1 1 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 Not Cancer Driver No 1 hippie 56 146 13 13 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 1 hippie 182 749 132 132 0
HDGF_ENST00000357325 HDGF P51858 Hepatoma-derived growth factor chr1 Not Cancer Driver No 1 intact, hippie 35 203 29 29 0
HLA-B HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 Compendium Yes 1 hippie 78 169 34 34 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
HNRNPM HNRNPM P52272 Heterogeneous nuclear ribonucleoprotein M chr19 Not Cancer Driver No 1 hippie, biogrid 108 463 67 67 0
HTRA4 HTRA4 P83105 Serine protease HTRA4 chr8 Not Cancer Driver No 1 hippie 57 15 0 0 0
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 Not Cancer Driver No 1 hippie, biogrid 155 419 90 90 0
INTS14_ENST00000313182 INTS14 Q96SY0 Integrator complex subunit 14 chr15 Not Cancer Driver No 1 hippie 63 118 12 12 0
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 Not Cancer Driver No 1 hippie 183 351 35 35 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KCMF1 KCMF1 Q9P0J7 E3 ubiquitin-protein ligase KCMF1 chr2 Not Cancer Driver No 1 hippie 48 270 36 36 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 Not Cancer Driver No 1 hippie 54 65 16 16 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact 519 90 17 17 23
MAP1LC3A_ENST00000397709 MAP1LC3A Q9H492 Microtubule-associated proteins 1A/1B light chain 3A chr20 Not Cancer Driver No 1 hippie 22 24 1 1 0
MAP4K2 MAP4K2 Q12851 Mitogen-activated protein kinase kinase kinase kinase 2 chr11 Not Cancer Driver No 1 hippie 78 243 23 23 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 hippie 128 750 126 126 18
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie 104 275 38 38 1
MINK1 MINK1 Q8N4C8 Misshapen-like kinase 1 chr17 Not Cancer Driver No 1 hippie 113 740 56 56 0
MYLK4 MYLK4 Q86YV6 Myosin light chain kinase family member 4 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 67 77 14 14 0
NAA40 NAA40 Q86UY6 N-alpha-acetyltransferase 40 chr11 Not Cancer Driver No 1 hippie 22 30 3 3 0
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 Not Cancer Driver No 1 intact, hippie 37 181 12 12 1
NCSTN NCSTN Q92542 Nicastrin chr1 Not Cancer Driver No 1 hippie, biogrid 94 72 11 11 1
NDN NDN Q99608 Necdin chr15 Not Cancer Driver No 1 intact, hippie 123 117 42 42 0
NF2 NF2 P35240 Merlin chr22 Census, Compendium Yes 1 hippie 69 252 26 26 16
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 233 553 60 60 0
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 intact, hippie 31 33 2 2 0
OTUB2 OTUB2 Q96DC9 Ubiquitin thioesterase OTUB2 chr14 Not Cancer Driver No 1 hippie 30 0 0 0 0
PAGE4_ENST00000376141 PAGE4 O60829 P antigen family member 4 chrX Not Cancer Driver No 1 hippie 20 102 20 20 0
PAK1IP1 PAK1IP1 Q9NWT1 p21-activated protein kinase-interacting protein 1 chr6 Not Cancer Driver No 1 hippie 38 83 6 6 0
PAK4 PAK4 O96013 Serine/threonine-protein kinase PAK 4 chr19 Not Cancer Driver No 1 hippie 58 340 33 33 0
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PHF8 PHF8 Q9UPP1 Histone lysine demethylase PHF8 chrX Not Cancer Driver No 1 intact, hippie 154 603 93 93 1
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 Not Cancer Driver No 1 hippie 30 157 13 13 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PRKAB1 PRKAB1 Q9Y478 5'-AMP-activated protein kinase subunit beta-1 chr12 Not Cancer Driver No 1 intact, hippie 39 124 13 13 0
PRPF40A PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 hippie 83 694 57 57 0
PRPF8 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 Not Cancer Driver No 1 hippie 255 225 26 26 8
PSMC6_ENST00000606149 PSMC6 P62333 26S proteasome regulatory subunit 10B chr14 Not Cancer Driver No 1 hippie, biogrid 49 69 8 8 0
PSME3_ENST00000590720 PSME3 P61289 Proteasome activator complex subunit 3 chr17 Not Cancer Driver No 1 hippie 20 25 5 5 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 Census, Compendium Yes 1 hippie 505 76 4 4 41
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 Census, Compendium Yes 1 hippie 66 2 1 1 6
RACGAP1_ENST00000454520 RACGAP1 Q9H0H5 Rac GTPase-activating protein 1 chr12 Not Cancer Driver No 1 hippie 74 255 27 27 0
RAD18 RAD18 Q9NS91 E3 ubiquitin-protein ligase RAD18 chr3 Not Cancer Driver No 1 hippie 59 328 43 43 0
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 Not Cancer Driver No 1 hippie 158 796 115 115 0
RCC1_ENST00000373833 RCC1 P18754 Regulator of chromosome condensation chr1 Not Cancer Driver No 1 hippie, biogrid 54 143 15 15 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RIN3 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 Not Cancer Driver No 1 hippie 137 417 61 61 0
RIOK1 RIOK1 Q9BRS2 Serine/threonine-protein kinase RIO1 chr6 Not Cancer Driver No 1 hippie 69 301 37 37 0
RIPK4_ENST00000352483 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 intact, hippie, biogrid 119 232 34 34 3
RRP1B RRP1B Q14684 Ribosomal RNA processing protein 1 homolog B chr21 Not Cancer Driver No 1 intact, hippie 74 513 48 48 0
SERBP1 SERBP1 Q8NC51 Plasminogen activator inhibitor 1 RNA-binding protein chr1 Not Cancer Driver No 1 hippie 53 408 53 53 0
SH2D3C SH2D3C Q8N5H7 SH2 domain-containing protein 3C chr9 Not Cancer Driver No 1 intact, hippie 110 440 72 72 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 48 163 15 15 0
SNRNP70 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 Not Cancer Driver No 1 hippie 38 416 37 37 0
SNRPD1 SNRPD1 P62314 Small nuclear ribonucleoprotein Sm D1 chr18 Not Cancer Driver No 1 hippie, biogrid 10 80 4 4 0
SNRPD3 SNRPD3 P62318 Small nuclear ribonucleoprotein Sm D3 chr22 Not Cancer Driver No 1 hippie, biogrid 20 43 13 13 0
SRSF5_ENST00000557154 SRSF5 Q13243 Serine/arginine-rich splicing factor 5 chr14 Not Cancer Driver No 1 hippie, biogrid 50 189 40 40 0
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
TIFAB TIFAB Q6ZNK6 TRAF-interacting protein with FHA domain-containing protein B chr5 Not Cancer Driver No 1 intact, hippie 32 26 7 7 0
TNF TNF P01375 Tumor necrosis factor chr6 Not Cancer Driver No 1 hippie 24 45 3 3 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 Census, Compendium Yes 1 hippie 98 231 33 33 1
TNIK TNIK Q9UKE5 TRAF2 and NCK-interacting protein kinase chr3 Not Cancer Driver No 1 intact, hippie 254 781 156 156 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TRADD TRADD Q15628 Tumor necrosis factor receptor type 1-associated DEATH domain protein chr16 Not Cancer Driver No 1 intact, hippie 26 74 5 5 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 intact, hippie 67 62 7 7 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
U2AF2 U2AF2 P26368 Splicing factor U2AF 65 kDa subunit chr19 Compendium Yes 1 hippie, biogrid 78 191 28 28 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 intact, hippie 188 110 28 28 0
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 intact, hippie 142 117 36 36 133
VIM_ENST00000224237 VIM P08670 Vimentin chr10 Not Cancer Driver No 1 hippie, biogrid 84 316 57 57 1
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 30 35 3 3 0
WDR76 WDR76 Q9H967 WD repeat-containing protein 76 chr15 Not Cancer Driver No 1 hippie 60 288 33 33 0
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0
YBX1 YBX1 P67809 Y-box-binding protein 1 chr1 Not Cancer Driver No 1 intact 41 312 41 41 0
ZBTB38_ENST00000441582 ZBTB38 Q8NAP3 Zinc finger and BTB domain-containing protein 38 chr3 Not Cancer Driver No 1 hippie 137 648 73 73 0
ZC3H18_ENST00000301011 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 1 hippie 139 929 134 134 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0