Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ACIN1 | ACIN1 | Q9UKV3 | Apoptotic chromatin condensation inducer in the nucleus | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 157 | 1294 | 155 | 155 | 0 |
ACTB_ENST00000646664 | ACTB | P60709 | Actin, cytoplasmic 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 112 | 43 | 5 | 5 | 5 |
AGR2 | AGR2 | O95994 | Anterior gradient protein 2 homolog | chr7 | Not Cancer Driver | No | 1 | hippie | 23 | 20 | 2 | 2 | 0 |
APLP1 | APLP1 | P51693 | Amyloid beta precursor like protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 146 | 455 | 98 | 98 | 0 |
ATG16L1 | ATG16L1 | Q676U5 | Autophagy-related protein 16-1 | chr2 | Not Cancer Driver | No | 1 | hippie | 79 | 239 | 25 | 25 | 1 |
B2M | B2M | P61769 | Beta-2-microglobulin | chr15 | Census, Compendium | Yes | 1 | hippie, biogrid | 34 | 5 | 1 | 1 | 2 |
BAG6 | BAG6 | P46379 | Large proline-rich protein BAG6 | chr6 | Not Cancer Driver | No | 1 | hippie | 98 | 861 | 79 | 79 | 0 |
BCAR3_ENST00000260502 | BCAR3 | O75815 | Breast cancer anti-estrogen resistance protein 3 | chr1 | Not Cancer Driver | No | 1 | hippie | 102 | 395 | 42 | 42 | 0 |
BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | Census, Compendium | Yes | 1 | hippie | 77 | 98 | 16 | 16 | 0 |
BRD2_ENST00000374831 | BRD2 | P25440 | Bromodomain-containing protein 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 108 | 632 | 85 | 85 | 0 |
BRD3 | BRD3 | Q15059 | Bromodomain-containing protein 3 | chr9 | Census | Yes | 1 | hippie | 87 | 566 | 68 | 68 | 0 |
BRD4 | BRD4 | O60885 | Bromodomain-containing protein 4 | chr19 | Census, Compendium | Yes | 1 | hippie | 193 | 1182 | 172 | 172 | 0 |
CCT7 | CCT7 | Q99832 | T-complex protein 1 subunit eta | chr2 | Not Cancer Driver | No | 1 | hippie | 59 | 36 | 6 | 6 | 0 |
CD274 | CD274 | Q9NZQ7 | Programmed cell death 1 ligand 1 | chr9 | Census | Yes | 1 | hippie | 29 | 54 | 9 | 9 | 0 |
CDK2AP2 | CDK2AP2 | O75956 | Cyclin-dependent kinase 2-associated protein 2 | chr11 | Not Cancer Driver | No | 1 | hippie | 10 | 126 | 10 | 10 | 0 |
CHGB | CHGB | P05060 | Secretogranin-1 | chr20 | Not Cancer Driver | No | 1 | hippie | 174 | 575 | 153 | 153 | 0 |
CHKA | CHKA | P35790 | Choline kinase alpha | chr11 | Not Cancer Driver | No | 1 | hippie | 45 | 119 | 4 | 4 | 0 |
CIT_ENST00000261833 | CIT | O14578 | Citron Rho-interacting kinase | chr12 | Not Cancer Driver | No | 1 | hippie | 284 | 1017 | 160 | 160 | 3 |
CRELD2_ENST00000328268 | CRELD2 | Q6UXH1 | Protein disulfide isomerase CRELD2 | chr22 | Not Cancer Driver | No | 1 | hippie | 39 | 33 | 6 | 6 | 0 |
CSAD_ENST00000453446 | CSAD | Q9Y600 | Cysteine sulfinic acid decarboxylase | chr12 | Not Cancer Driver | No | 1 | hippie | 73 | 23 | 8 | 8 | 0 |
CSNK1A1_ENST00000377843 | CSNK1A1 | P48729 | Casein kinase I isoform alpha | chr5 | Not Cancer Driver | No | 1 | hippie | 44 | 46 | 3 | 3 | 0 |
CUL7_ENST00000265348 | CUL7 | Q14999 | Cullin-7 | chr6 | Not Cancer Driver | No | 1 | hippie | 188 | 372 | 41 | 41 | 3 |
DDAH2_ENST00000375787 | DDAH2 | O95865 | N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 24 | 96 | 6 | 6 | 0 |
DIS3 | DIS3 | Q9Y2L1 | Exosome complex exonuclease RRP44 | chr13 | Compendium | Yes | 1 | hippie, biogrid | 121 | 235 | 32 | 32 | 0 |
DLGAP5 | DLGAP5 | Q15398 | Disks large-associated protein 5 | chr14 | Not Cancer Driver | No | 2 | hippie, biogrid | 84 | 676 | 70 | 70 | 0 |
DNAJB2 | DNAJB2 | P25686 | DnaJ homolog subfamily B member 2 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 51 | 239 | 40 | 40 | 1 |
DNM1L_ENST00000549701 | DNM1L | O00429 | Dynamin-1-like protein | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 212 | 23 | 23 | 7 |
DYNC1I1 | DYNC1I1 | O14576 | Cytoplasmic dynein 1 intermediate chain 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 146 | 255 | 60 | 60 | 0 |
ENO1 | ENO1 | P06733 | Alpha-enolase | chr1 | Not Cancer Driver | No | 1 | hippie | 51 | 21 | 2 | 2 | 0 |
EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | Census, Compendium | Yes | 1 | hippie | 334 | 1790 | 196 | 196 | 1 |
ERCC6 | ERCC6 | Q03468 | DNA excision repair protein ERCC-6 | chr10 | Not Cancer Driver | No | 1 | hippie | 211 | 829 | 117 | 117 | 9 |
ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
EZH2_ENST00000460911 | EZH2 | Q15910 | Histone-lysine N-methyltransferase EZH2 | chr7 | Census, Compendium | Yes | 1 | hippie | 120 | 284 | 44 | 44 | 11 |
FAF1 | FAF1 | Q9UNN5 | FAS-associated factor 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 83 | 241 | 34 | 34 | 0 |
FANCD2_ENST00000383807 | FANCD2 | Q9BXW9 | Fanconi anemia group D2 protein | chr3 | Census, Compendium | Yes | 1 | hippie | 176 | 181 | 14 | 14 | 3 |
FBXO7 | FBXO7 | Q9Y3I1 | F-box only protein 7 | chr22 | Not Cancer Driver | No | 1 | hippie | 75 | 243 | 38 | 38 | 1 |
FLAD1 | FLAD1 | Q8NFF5 | FAD synthase | chr1 | Not Cancer Driver | No | 1 | hippie | 81 | 59 | 6 | 6 | 1 |
FN1 | FN1 | P02751 | Fibronectin | chr2 | Compendium | Yes | 1 | hippie | 394 | 1243 | 185 | 185 | 8 |
FOXA1 | FOXA1 | P55317 | Hepatocyte nuclear factor 3-alpha | chr14 | Census, Compendium | Yes | 1 | hippie | 100 | 295 | 53 | 53 | 0 |
FOXB1 | FOXB1 | Q99853 | Forkhead box protein B1 | chr15 | Not Cancer Driver | No | 1 | hippie | 31 | 114 | 5 | 5 | 0 |
FOXE1 | FOXE1 | O00358 | Forkhead box protein E1 | chr9 | Not Cancer Driver | No | 1 | hippie | 38 | 133 | 5 | 5 | 4 |
FOXH1 | FOXH1 | O75593 | Forkhead box protein H1 | chr8 | Not Cancer Driver | No | 1 | hippie | 47 | 215 | 25 | 25 | 0 |
FOXI2 | FOXI2 | Q6ZQN5 | Forkhead box protein I2 | chr10 | Not Cancer Driver | No | 1 | hippie | 32 | 165 | 22 | 22 | 0 |
FOXP1_ENST00000318789 | FOXP1 | Q9H334 | Forkhead box protein P1 | chr3 | Census, Compendium | Yes | 1 | hippie | 109 | 448 | 71 | 71 | 3 |
FOXQ1 | FOXQ1 | Q9C009 | Forkhead box protein Q1 | chr6 | Not Cancer Driver | No | 1 | hippie | 22 | 245 | 4 | 4 | 0 |
G3BP1 | G3BP1 | Q13283 | Ras GTPase-activating protein-binding protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 85 | 352 | 65 | 65 | 0 |
GLYR1 | GLYR1 | Q49A26 | Putative oxidoreductase GLYR1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 87 | 201 | 27 | 27 | 0 |
GNB2 | GNB2 | P62879 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 | chr7 | Not Cancer Driver | No | 1 | hippie | 50 | 21 | 0 | 0 | 7 |
HADHB | HADHB | P55084 | Trifunctional enzyme subunit beta, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 71 | 41 | 9 | 9 | 14 |
HDAC9_ENST00000432645 | HDAC9 | Q9UKV0 | Histone deacetylase 9 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 286 | 631 | 178 | 178 | 0 |
HDGF_ENST00000357325 | HDGF | P51858 | Hepatoma-derived growth factor | chr1 | Not Cancer Driver | No | 1 | hippie | 35 | 203 | 29 | 29 | 0 |
HLA-B | HLA-B | P01889 | HLA class I histocompatibility antigen, B alpha chain | chr6 | Compendium | Yes | 1 | hippie | 78 | 169 | 34 | 34 | 0 |
HMGA1 | HMGA1 | P17096 | High mobility group protein HMG-I/HMG-Y | chr6 | Census | Yes | 1 | hippie | 6 | 107 | 6 | 6 | 0 |
HNRNPH1 | HNRNPH1 | P31943 | Heterogeneous nuclear ribonucleoprotein H | chr5 | Not Cancer Driver | No | 1 | hippie | 51 | 169 | 29 | 29 | 0 |
HNRNPK_ENST00000351839 | HNRNPK | P61978 | Heterogeneous nuclear ribonucleoprotein K | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 75 | 302 | 59 | 59 | 0 |
HNRNPM | HNRNPM | P52272 | Heterogeneous nuclear ribonucleoprotein M | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 108 | 463 | 67 | 67 | 0 |
HOXD8 | HOXD8 | P13378 | Homeobox protein Hox-D8 | chr2 | Not Cancer Driver | No | 1 | hippie | 31 | 199 | 24 | 24 | 0 |
IFITM3 | IFITM3 | Q01628 | Interferon-induced transmembrane protein 3 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 69 | 18 | 5 | 5 | 0 |
ITGA4 | ITGA4 | P13612 | Integrin alpha-4 | chr2 | Not Cancer Driver | No | 1 | hippie | 254 | 97 | 27 | 27 | 0 |
JUN | JUN | P05412 | Transcription factor Jun | chr1 | Census | Yes | 1 | hippie | 35 | 281 | 25 | 25 | 0 |
KDM4C | KDM4C | Q9H3R0 | Lysine-specific demethylase 4C | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 124 | 309 | 40 | 40 | 0 |
KIF14 | KIF14 | Q15058 | Kinesin-like protein KIF14 | chr1 | Not Cancer Driver | No | 1 | hippie | 222 | 774 | 102 | 102 | 2 |
KMT2B | KMT2B | Q9UMN6 | Histone-lysine N-methyltransferase 2B | chr19 | Compendium | Yes | 1 | hippie | 378 | 1895 | 227 | 227 | 0 |
KPNA3 | KPNA3 | O00505 | Importin subunit alpha-4 | chr13 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 65 | 108 | 11 | 11 | 0 |
KPNA4 | KPNA4 | O00629 | Importin subunit alpha-3 | chr3 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 59 | 112 | 12 | 12 | 0 |
KPNB1 | KPNB1 | Q14974 | Importin subunit beta-1 | chr17 | Not Cancer Driver | No | 3 | hippie, biogrid | 92 | 94 | 11 | 11 | 0 |
KSR1_ENST00000644974 | KSR1 | Q8IVT5 | Kinase suppressor of Ras 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 114 | 404 | 58 | 58 | 0 |
LGALS9 | LGALS9 | O00182 | Galectin-9 | chr17 | Not Cancer Driver | No | 1 | hippie | 54 | 65 | 16 | 16 | 0 |
LRIF1 | LRIF1 | Q5T3J3 | Ligand-dependent nuclear receptor-interacting factor 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 116 | 520 | 74 | 74 | 0 |
LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact | 519 | 90 | 17 | 17 | 23 |
LUC7L3_ENST00000240304 | LUC7L3 | O95232 | Luc7-like protein 3 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 59 | 323 | 47 | 47 | 0 |
MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | Census, Compendium | Yes | 1 | hippie | 56 | 297 | 37 | 37 | 0 |
MOV10_ENST00000357443 | MOV10 | Q9HCE1 | Helicase MOV-10 | chr1 | Not Cancer Driver | No | 1 | hippie | 110 | 101 | 8 | 8 | 0 |
MTDH | MTDH | Q86UE4 | Protein LYRIC | chr8 | Not Cancer Driver | No | 1 | hippie | 83 | 516 | 81 | 81 | 0 |
MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
MYLK2 | MYLK2 | Q9H1R3 | Myosin light chain kinase 2, skeletal/cardiac muscle | chr20 | Not Cancer Driver | No | 1 | hippie | 118 | 277 | 64 | 64 | 2 |
NAV1 | NAV1 | Q8NEY1 | Neuron navigator 1 | chr1 | Not Cancer Driver | No | 3 | intact, biogrid | 225 | 1455 | 167 | 167 | 0 |
NCSTN | NCSTN | Q92542 | Nicastrin | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 94 | 72 | 11 | 11 | 1 |
NEDD8 | NEDD8 | Q15843 | NEDD8 | chr14 | Not Cancer Driver | No | 1 | hippie | 10 | 36 | 5 | 5 | 0 |
NEMP1 | NEMP1 | O14524 | Nuclear envelope integral membrane protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie | 32 | 36 | 5 | 5 | 0 |
NGFR | NGFR | P08138 | Tumor necrosis factor receptor superfamily member 16 | chr17 | Not Cancer Driver | No | 1 | hippie | 57 | 172 | 25 | 25 | 0 |
NKX2-1_ENST00000518149 | NKX2-1 | P43699 | Homeobox protein Nkx-2.1 | chr14 | Census, Compendium | Yes | 1 | hippie | 41 | 334 | 39 | 39 | 7 |
NTMT1_ENST00000613644 | NTMT1 | Q9BV86 | N-terminal Xaa-Pro-Lys N-methyltransferase 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 27 | 1 | 0 | 0 | 0 |
NUDT21 | NUDT21 | O43809 | Cleavage and polyadenylation specificity factor subunit 5 | chr16 | Not Cancer Driver | No | 1 | hippie | 21 | 37 | 3 | 3 | 0 |
NUP107 | NUP107 | P57740 | Nuclear pore complex protein Nup107 | chr12 | Not Cancer Driver | No | 1 | hippie | 127 | 183 | 26 | 26 | 5 |
NUP153_ENST00000262077 | NUP153 | P49790 | Nuclear pore complex protein Nup153 | chr6 | Not Cancer Driver | No | 1 | hippie | 180 | 1152 | 147 | 147 | 0 |
NUP98_ENST00000359171 | NUP98 | P52948 | Nuclear pore complex protein Nup98-Nup96 | chr11 | Census | Yes | 1 | hippie | 227 | 1008 | 107 | 107 | 0 |
NUPR1_ENST00000324873 | NUPR1 | O60356 | Nuclear protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 10 | 82 | 10 | 10 | 0 |
NUSAP1 | NUSAP1 | Q9BXS6 | Nucleolar and spindle-associated protein 1 | chr15 | Not Cancer Driver | No | 3 | hippie, biogrid | 49 | 415 | 42 | 42 | 0 |
NXF1_ENST00000294172 | NXF1 | Q9UBU9 | Nuclear RNA export factor 1 | chr11 | Compendium | Yes | 1 | hippie | 100 | 163 | 32 | 32 | 0 |
OBSL1 | OBSL1 | O75147 | Obscurin-like protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 233 | 553 | 60 | 60 | 0 |
OGT | OGT | O15294 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | chrX | Not Cancer Driver | No | 1 | hippie | 156 | 89 | 16 | 16 | 2 |
OTUB1_ENST00000428192 | OTUB1 | Q96FW1 | Ubiquitin thioesterase OTUB1 | chr11 | Not Cancer Driver | No | 1 | hippie | 31 | 33 | 2 | 2 | 0 |
PDHB | PDHB | P11177 | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie | 32 | 4 | 0 | 0 | 2 |
PKM_ENST00000335181 | PKM | P14618 | Pyruvate kinase PKM | chr15 | Not Cancer Driver | No | 1 | hippie | 78 | 58 | 13 | 13 | 0 |
PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
PPM1G | PPM1G | O15355 | Protein phosphatase 1G | chr2 | Not Cancer Driver | No | 1 | hippie | 51 | 359 | 39 | 39 | 0 |
PRKAB1 | PRKAB1 | Q9Y478 | 5'-AMP-activated protein kinase subunit beta-1 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 39 | 124 | 13 | 13 | 0 |
PTMA | PTMA | P06454 | Prothymosin alpha | chr2 | Compendium | Yes | 1 | hippie | 10 | 111 | 10 | 10 | 0 |
RANBP1_ENST00000331821 | RANBP1 | P43487 | Ran-specific GTPase-activating protein | chr22 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 19 | 137 | 16 | 16 | 0 |
RANBP2 | RANBP2 | P49792 | E3 SUMO-protein ligase RanBP2 | chr2 | Census, Compendium | Yes | 3 | intact, hippie, biogrid | 427 | 1387 | 177 | 177 | 3 |
RANBP3 | RANBP3 | Q9H6Z4 | Ran-binding protein 3 | chr19 | Not Cancer Driver | No | 2 | hippie, biogrid | 71 | 468 | 54 | 54 | 0 |
RANGAP1_ENST00000356244 | RANGAP1 | P46060 | Ran GTPase-activating protein 1 | chr22 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 65 | 159 | 17 | 17 | 0 |
RAN_ENST00000392369 | RAN | P62826 | GTP-binding nuclear protein Ran | chr12 | Not Cancer Driver | No | 6 | hippie, biogrid | 20 | 14 | 1 | 1 | 0 |
RBM14 | RBM14 | Q96PK6 | RNA-binding protein 14 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 99 | 350 | 59 | 59 | 0 |
RBM39 | RBM39 | Q14498 | RNA-binding protein 39 | chr20 | Compendium | Yes | 1 | hippie | 81 | 228 | 39 | 39 | 0 |
RBPJ_ENST00000361572 | RBPJ | Q06330 | Recombining binding protein suppressor of hairless | chr4 | Not Cancer Driver | No | 1 | hippie | 49 | 151 | 19 | 19 | 2 |
RCC1_ENST00000373833 | RCC1 | P18754 | Regulator of chromosome condensation | chr1 | Not Cancer Driver | No | 1 | hippie | 54 | 143 | 15 | 15 | 0 |
RCC2 | RCC2 | Q9P258 | Protein RCC2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 63 | 194 | 27 | 27 | 0 |
RECQL4 | RECQL4 | O94761 | ATP-dependent DNA helicase Q4 | chr8 | Census, Compendium | Yes | 1 | hippie | 138 | 608 | 71 | 71 | 1 |
RGPD1 | RGPD1 | P0DJD0 | RANBP2-like and GRIP domain-containing protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 634 | 10 | 10 | 0 |
RGPD3 | RGPD3 | A6NKT7 | RanBP2-like and GRIP domain-containing protein 3 | chr2 | Census, Compendium | Yes | 3 | intact, hippie, biogrid | 339 | 605 | 195 | 195 | 0 |
RGPD5_ENST00000393283 | RGPD5 | Q99666-2 | Isoform 2 of RANBP2-like and GRIP domain-containing protein 5/6 | chr2 | Not Cancer Driver | No | 3 | biogrid | 1 | 141 | 1 | 1 | 0 |
RGPD8 | RGPD8 | O14715 | RANBP2-like and GRIP domain-containing protein 8 | chr2 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 129 | 621 | 71 | 71 | 0 |
RIPK4_ENST00000352483 | RIPK4 | P57078 | Receptor-interacting serine/threonine-protein kinase 4 | chr21 | Not Cancer Driver | No | 1 | hippie | 119 | 232 | 34 | 34 | 3 |
RNF2 | RNF2 | Q99496 | E3 ubiquitin-protein ligase RING2 | chr1 | Not Cancer Driver | No | 1 | hippie | 40 | 203 | 22 | 22 | 0 |
RPA1 | RPA1 | P27694 | Replication protein A 70 kDa DNA-binding subunit | chr17 | Not Cancer Driver | No | 1 | hippie | 51 | 98 | 6 | 6 | 0 |
SDF4 | SDF4 | Q9BRK5 | 45 kDa calcium-binding protein | chr1 | Not Cancer Driver | No | 1 | hippie | 48 | 187 | 30 | 30 | 0 |
SEC63 | SEC63 | Q9UGP8 | Translocation protein SEC63 homolog | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 98 | 266 | 37 | 37 | 0 |
SF3B6 | SF3B6 | Q9Y3B4 | Splicing factor 3B subunit 6 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 9 | 10 | 0 | 0 | 0 |
SHMT2 | SHMT2 | P34897 | Serine hydroxymethyltransferase, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie | 57 | 58 | 5 | 5 | 1 |
SLC25A28 | SLC25A28 | Q96A46 | Mitoferrin-2 | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 43 | 80 | 0 | 0 | 0 |
SPRED1 | SPRED1 | Q7Z699 | Sprouty-related, EVH1 domain-containing protein 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 71 | 194 | 35 | 35 | 2 |
SUMO1_ENST00000392245 | SUMO1 | P63165 | Small ubiquitin-related modifier 1 | chr2 | Not Cancer Driver | No | 2 | hippie, biogrid | 10 | 76 | 7 | 7 | 0 |
SUMO2 | SUMO2 | P61956 | Small ubiquitin-related modifier 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 9 | 69 | 6 | 6 | 0 |
SUZ12 | SUZ12 | Q15022 | Polycomb protein SUZ12 | chr17 | Census, Compendium | Yes | 1 | hippie | 83 | 483 | 46 | 46 | 3 |
TAL1 | TAL1 | P17542 | T-cell acute lymphocytic leukemia protein 1 | chr1 | Census | Yes | 1 | hippie | 54 | 305 | 53 | 53 | 0 |
TEAD2_ENST00000311227 | TEAD2 | Q15562 | Transcriptional enhancer factor TEF-4 | chr19 | Not Cancer Driver | No | 1 | hippie | 66 | 220 | 31 | 31 | 0 |
TLE1 | TLE1 | Q04724 | Transducin-like enhancer protein 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 111 | 381 | 53 | 53 | 0 |
TNIK | TNIK | Q9UKE5 | TRAF2 and NCK-interacting protein kinase | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 254 | 781 | 156 | 156 | 0 |
TNIP2 | TNIP2 | Q8NFZ5 | TNFAIP3-interacting protein 2 | chr4 | Not Cancer Driver | No | 1 | hippie | 43 | 316 | 36 | 36 | 0 |
TOP3B_ENST00000357179 | TOP3B | O95985 | DNA topoisomerase 3-beta-1 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 102 | 151 | 17 | 17 | 0 |
TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 1 | hippie | 2891 | 282 | 1466 | 1466 | 83 |
TRAF6_ENST00000348124 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 67 | 62 | 7 | 7 | 0 |
TRIM25 | TRIM25 | Q14258 | E3 ubiquitin/ISG15 ligase TRIM25 | chr17 | Not Cancer Driver | No | 1 | hippie | 59 | 225 | 20 | 20 | 0 |
TRIM28 | TRIM28 | Q13263 | Transcription intermediary factor 1-beta | chr19 | Not Cancer Driver | No | 1 | hippie | 87 | 430 | 41 | 41 | 0 |
TRMT2A_ENST00000403707 | TRMT2A | Q8IZ69 | tRNA (uracil-5-)-methyltransferase homolog A | chr22 | Not Cancer Driver | No | 1 | hippie | 64 | 157 | 20 | 20 | 0 |
TUBB3 | TUBB3 | Q13509 | Tubulin beta-3 chain | chr16 | Not Cancer Driver | No | 1 | hippie | 67 | 53 | 10 | 10 | 12 |
U2AF1 | U2AF1 | Q01081 | Splicing factor U2AF 35 kDa subunit | chr21 | Census, Compendium | Yes | 1 | hippie, biogrid | 70 | 73 | 13 | 13 | 3 |
UBE2I | UBE2I | P63279 | SUMO-conjugating enzyme UBC9 | chr16 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 16 | 16 | 3 | 3 | 0 |
UNC119 | UNC119 | Q13432 | Protein unc-119 homolog A | chr17 | Not Cancer Driver | No | 1 | hippie | 20 | 89 | 4 | 4 | 1 |
USP4 | USP4 | Q13107 | Ubiquitin carboxyl-terminal hydrolase 4 | chr3 | Not Cancer Driver | No | 1 | hippie | 102 | 286 | 22 | 22 | 0 |
VCAM1 | VCAM1 | P19320 | Vascular cell adhesion protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 188 | 110 | 28 | 28 | 0 |
VRK1 | VRK1 | Q99986 | Serine/threonine-protein kinase VRK1 | chr14 | Not Cancer Driver | No | 1 | hippie | 52 | 80 | 9 | 9 | 0 |
WDR5 | WDR5 | P61964 | WD repeat-containing protein 5 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 35 | 3 | 3 | 0 |
WIZ_ENST00000263381 | WIZ | O95785-2 | Isoform 2 of Protein Wiz | chr19 | Not Cancer Driver | No | 1 | hippie | 148 | 651 | 135 | 135 | 0 |
XPO1_ENST00000406957 | XPO1 | O14980 | Exportin-1 | chr2 | Census, Compendium | Yes | 2 | hippie, biogrid | 140 | 33 | 9 | 9 | 0 |
ZDHHC5 | ZDHHC5 | Q9C0B5 | Palmitoyltransferase ZDHHC5 | chr11 | Not Cancer Driver | No | 1 | hippie | 89 | 462 | 63 | 63 | 0 |
ZNF135_ENST00000313434 | ZNF135 | P52742 | Zinc finger protein 135 | chr19 | Not Cancer Driver | No | 1 | hippie | 137 | 207 | 50 | 50 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|