Filter in search result
RCC1_ENST00000373833 ,RCC1 ,P18754
  • Number of Interaction partner in intact: 15
  • Number of Interaction partner in biogrid: 37
  • Number of Interaction partner in hippie: 146
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACIN1 ACIN1 Q9UKV3 Apoptotic chromatin condensation inducer in the nucleus chr14 Not Cancer Driver No 1 hippie, biogrid 157 1294 155 155 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie 112 43 5 5 5
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 Not Cancer Driver No 1 hippie 23 20 2 2 0
APLP1 APLP1 P51693 Amyloid beta precursor like protein 1 chr19 Not Cancer Driver No 1 hippie 146 455 98 98 0
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 79 239 25 25 1
B2M B2M P61769 Beta-2-microglobulin chr15 Census, Compendium Yes 1 hippie, biogrid 34 5 1 1 2
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 Not Cancer Driver No 1 hippie 98 861 79 79 0
BCAR3_ENST00000260502 BCAR3 O75815 Breast cancer anti-estrogen resistance protein 3 chr1 Not Cancer Driver No 1 hippie 102 395 42 42 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BRD2_ENST00000374831 BRD2 P25440 Bromodomain-containing protein 2 chr6 Not Cancer Driver No 1 hippie 108 632 85 85 0
BRD3 BRD3 Q15059 Bromodomain-containing protein 3 chr9 Census Yes 1 hippie 87 566 68 68 0
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
CCT7 CCT7 Q99832 T-complex protein 1 subunit eta chr2 Not Cancer Driver No 1 hippie 59 36 6 6 0
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 Census Yes 1 hippie 29 54 9 9 0
CDK2AP2 CDK2AP2 O75956 Cyclin-dependent kinase 2-associated protein 2 chr11 Not Cancer Driver No 1 hippie 10 126 10 10 0
CHGB CHGB P05060 Secretogranin-1 chr20 Not Cancer Driver No 1 hippie 174 575 153 153 0
CHKA CHKA P35790 Choline kinase alpha chr11 Not Cancer Driver No 1 hippie 45 119 4 4 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CRELD2_ENST00000328268 CRELD2 Q6UXH1 Protein disulfide isomerase CRELD2 chr22 Not Cancer Driver No 1 hippie 39 33 6 6 0
CSAD_ENST00000453446 CSAD Q9Y600 Cysteine sulfinic acid decarboxylase chr12 Not Cancer Driver No 1 hippie 73 23 8 8 0
CSNK1A1_ENST00000377843 CSNK1A1 P48729 Casein kinase I isoform alpha chr5 Not Cancer Driver No 1 hippie 44 46 3 3 0
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 188 372 41 41 3
DDAH2_ENST00000375787 DDAH2 O95865 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 chr6 Not Cancer Driver No 1 hippie 24 96 6 6 0
DIS3 DIS3 Q9Y2L1 Exosome complex exonuclease RRP44 chr13 Compendium Yes 1 hippie, biogrid 121 235 32 32 0
DLGAP5 DLGAP5 Q15398 Disks large-associated protein 5 chr14 Not Cancer Driver No 2 hippie, biogrid 84 676 70 70 0
DNAJB2 DNAJB2 P25686 DnaJ homolog subfamily B member 2 chr2 Not Cancer Driver No 1 hippie, biogrid 51 239 40 40 1
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 Not Cancer Driver No 1 hippie, biogrid 67 212 23 23 7
DYNC1I1 DYNC1I1 O14576 Cytoplasmic dynein 1 intermediate chain 1 chr7 Not Cancer Driver No 1 hippie 146 255 60 60 0
ENO1 ENO1 P06733 Alpha-enolase chr1 Not Cancer Driver No 1 hippie 51 21 2 2 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 Not Cancer Driver No 1 hippie 211 829 117 117 9
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 Not Cancer Driver No 1 hippie 90 92 11 11 1
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 Census, Compendium Yes 1 hippie 120 284 44 44 11
FAF1 FAF1 Q9UNN5 FAS-associated factor 1 chr1 Not Cancer Driver No 1 hippie 83 241 34 34 0
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 176 181 14 14 3
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 Not Cancer Driver No 1 hippie 75 243 38 38 1
FLAD1 FLAD1 Q8NFF5 FAD synthase chr1 Not Cancer Driver No 1 hippie 81 59 6 6 1
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 hippie 394 1243 185 185 8
FOXA1 FOXA1 P55317 Hepatocyte nuclear factor 3-alpha chr14 Census, Compendium Yes 1 hippie 100 295 53 53 0
FOXB1 FOXB1 Q99853 Forkhead box protein B1 chr15 Not Cancer Driver No 1 hippie 31 114 5 5 0
FOXE1 FOXE1 O00358 Forkhead box protein E1 chr9 Not Cancer Driver No 1 hippie 38 133 5 5 4
FOXH1 FOXH1 O75593 Forkhead box protein H1 chr8 Not Cancer Driver No 1 hippie 47 215 25 25 0
FOXI2 FOXI2 Q6ZQN5 Forkhead box protein I2 chr10 Not Cancer Driver No 1 hippie 32 165 22 22 0
FOXP1_ENST00000318789 FOXP1 Q9H334 Forkhead box protein P1 chr3 Census, Compendium Yes 1 hippie 109 448 71 71 3
FOXQ1 FOXQ1 Q9C009 Forkhead box protein Q1 chr6 Not Cancer Driver No 1 hippie 22 245 4 4 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 hippie 85 352 65 65 0
GLYR1 GLYR1 Q49A26 Putative oxidoreductase GLYR1 chr16 Not Cancer Driver No 1 hippie, biogrid 87 201 27 27 0
GNB2 GNB2 P62879 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 chr7 Not Cancer Driver No 1 hippie 50 21 0 0 7
HADHB HADHB P55084 Trifunctional enzyme subunit beta, mitochondrial chr2 Not Cancer Driver No 1 hippie 71 41 9 9 14
HDAC9_ENST00000432645 HDAC9 Q9UKV0 Histone deacetylase 9 chr7 Not Cancer Driver No 1 hippie, biogrid 286 631 178 178 0
HDGF_ENST00000357325 HDGF P51858 Hepatoma-derived growth factor chr1 Not Cancer Driver No 1 hippie 35 203 29 29 0
HLA-B HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 Compendium Yes 1 hippie 78 169 34 34 0
HMGA1 HMGA1 P17096 High mobility group protein HMG-I/HMG-Y chr6 Census Yes 1 hippie 6 107 6 6 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
HNRNPK_ENST00000351839 HNRNPK P61978 Heterogeneous nuclear ribonucleoprotein K chr9 Not Cancer Driver No 1 hippie, biogrid 75 302 59 59 0
HNRNPM HNRNPM P52272 Heterogeneous nuclear ribonucleoprotein M chr19 Not Cancer Driver No 1 hippie, biogrid 108 463 67 67 0
HOXD8 HOXD8 P13378 Homeobox protein Hox-D8 chr2 Not Cancer Driver No 1 hippie 31 199 24 24 0
IFITM3 IFITM3 Q01628 Interferon-induced transmembrane protein 3 chr11 Not Cancer Driver No 1 intact, hippie 69 18 5 5 0
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 Not Cancer Driver No 1 hippie 254 97 27 27 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KDM4C KDM4C Q9H3R0 Lysine-specific demethylase 4C chr9 Not Cancer Driver No 1 hippie, biogrid 124 309 40 40 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KMT2B KMT2B Q9UMN6 Histone-lysine N-methyltransferase 2B chr19 Compendium Yes 1 hippie 378 1895 227 227 0
KPNA3 KPNA3 O00505 Importin subunit alpha-4 chr13 Not Cancer Driver No 4 intact, hippie, biogrid 65 108 11 11 0
KPNA4 KPNA4 O00629 Importin subunit alpha-3 chr3 Not Cancer Driver No 4 intact, hippie, biogrid 59 112 12 12 0
KPNB1 KPNB1 Q14974 Importin subunit beta-1 chr17 Not Cancer Driver No 3 hippie, biogrid 92 94 11 11 0
KSR1_ENST00000644974 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 Not Cancer Driver No 1 hippie 114 404 58 58 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 Not Cancer Driver No 1 hippie 54 65 16 16 0
LRIF1 LRIF1 Q5T3J3 Ligand-dependent nuclear receptor-interacting factor 1 chr1 Not Cancer Driver No 1 hippie 116 520 74 74 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact 519 90 17 17 23
LUC7L3_ENST00000240304 LUC7L3 O95232 Luc7-like protein 3 chr17 Not Cancer Driver No 1 hippie, biogrid 59 323 47 47 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 56 297 37 37 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MTDH MTDH Q86UE4 Protein LYRIC chr8 Not Cancer Driver No 1 hippie 83 516 81 81 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYLK2 MYLK2 Q9H1R3 Myosin light chain kinase 2, skeletal/cardiac muscle chr20 Not Cancer Driver No 1 hippie 118 277 64 64 2
NAV1 NAV1 Q8NEY1 Neuron navigator 1 chr1 Not Cancer Driver No 3 intact, biogrid 225 1455 167 167 0
NCSTN NCSTN Q92542 Nicastrin chr1 Not Cancer Driver No 1 hippie, biogrid 94 72 11 11 1
NEDD8 NEDD8 Q15843 NEDD8 chr14 Not Cancer Driver No 1 hippie 10 36 5 5 0
NEMP1 NEMP1 O14524 Nuclear envelope integral membrane protein 1 chr12 Not Cancer Driver No 1 hippie 32 36 5 5 0
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 Not Cancer Driver No 1 hippie 57 172 25 25 0
NKX2-1_ENST00000518149 NKX2-1 P43699 Homeobox protein Nkx-2.1 chr14 Census, Compendium Yes 1 hippie 41 334 39 39 7
NTMT1_ENST00000613644 NTMT1 Q9BV86 N-terminal Xaa-Pro-Lys N-methyltransferase 1 chr9 Not Cancer Driver No 1 hippie 27 1 0 0 0
NUDT21 NUDT21 O43809 Cleavage and polyadenylation specificity factor subunit 5 chr16 Not Cancer Driver No 1 hippie 21 37 3 3 0
NUP107 NUP107 P57740 Nuclear pore complex protein Nup107 chr12 Not Cancer Driver No 1 hippie 127 183 26 26 5
NUP153_ENST00000262077 NUP153 P49790 Nuclear pore complex protein Nup153 chr6 Not Cancer Driver No 1 hippie 180 1152 147 147 0
NUP98_ENST00000359171 NUP98 P52948 Nuclear pore complex protein Nup98-Nup96 chr11 Census Yes 1 hippie 227 1008 107 107 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
NUSAP1 NUSAP1 Q9BXS6 Nucleolar and spindle-associated protein 1 chr15 Not Cancer Driver No 3 hippie, biogrid 49 415 42 42 0
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 1 hippie 233 553 60 60 0
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX Not Cancer Driver No 1 hippie 156 89 16 16 2
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 Not Cancer Driver No 1 hippie 31 33 2 2 0
PDHB PDHB P11177 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial chr3 Not Cancer Driver No 1 hippie 32 4 0 0 2
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 Not Cancer Driver No 1 hippie 78 58 13 13 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PPM1G PPM1G O15355 Protein phosphatase 1G chr2 Not Cancer Driver No 1 hippie 51 359 39 39 0
PRKAB1 PRKAB1 Q9Y478 5'-AMP-activated protein kinase subunit beta-1 chr12 Not Cancer Driver No 1 intact, hippie 39 124 13 13 0
PTMA PTMA P06454 Prothymosin alpha chr2 Compendium Yes 1 hippie 10 111 10 10 0
RANBP1_ENST00000331821 RANBP1 P43487 Ran-specific GTPase-activating protein chr22 Not Cancer Driver No 5 intact, hippie, biogrid 19 137 16 16 0
RANBP2 RANBP2 P49792 E3 SUMO-protein ligase RanBP2 chr2 Census, Compendium Yes 3 intact, hippie, biogrid 427 1387 177 177 3
RANBP3 RANBP3 Q9H6Z4 Ran-binding protein 3 chr19 Not Cancer Driver No 2 hippie, biogrid 71 468 54 54 0
RANGAP1_ENST00000356244 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 Not Cancer Driver No 3 intact, hippie, biogrid 65 159 17 17 0
RAN_ENST00000392369 RAN P62826 GTP-binding nuclear protein Ran chr12 Not Cancer Driver No 6 hippie, biogrid 20 14 1 1 0
RBM14 RBM14 Q96PK6 RNA-binding protein 14 chr11 Not Cancer Driver No 1 hippie, biogrid 99 350 59 59 0
RBM39 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 81 228 39 39 0
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 Not Cancer Driver No 1 hippie 49 151 19 19 2
RCC1_ENST00000373833 RCC1 P18754 Regulator of chromosome condensation chr1 Not Cancer Driver No 1 hippie 54 143 15 15 0
RCC2 RCC2 Q9P258 Protein RCC2 chr1 Not Cancer Driver No 1 hippie, biogrid 63 194 27 27 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
RGPD1 RGPD1 P0DJD0 RANBP2-like and GRIP domain-containing protein 1 chr2 Not Cancer Driver No 1 hippie, biogrid 31 634 10 10 0
RGPD3 RGPD3 A6NKT7 RanBP2-like and GRIP domain-containing protein 3 chr2 Census, Compendium Yes 3 intact, hippie, biogrid 339 605 195 195 0
RGPD5_ENST00000393283 RGPD5 Q99666-2 Isoform 2 of RANBP2-like and GRIP domain-containing protein 5/6 chr2 Not Cancer Driver No 3 biogrid 1 141 1 1 0
RGPD8 RGPD8 O14715 RANBP2-like and GRIP domain-containing protein 8 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 129 621 71 71 0
RIPK4_ENST00000352483 RIPK4 P57078 Receptor-interacting serine/threonine-protein kinase 4 chr21 Not Cancer Driver No 1 hippie 119 232 34 34 3
RNF2 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 1 hippie 40 203 22 22 0
RPA1 RPA1 P27694 Replication protein A 70 kDa DNA-binding subunit chr17 Not Cancer Driver No 1 hippie 51 98 6 6 0
SDF4 SDF4 Q9BRK5 45 kDa calcium-binding protein chr1 Not Cancer Driver No 1 hippie 48 187 30 30 0
SEC63 SEC63 Q9UGP8 Translocation protein SEC63 homolog chr6 Not Cancer Driver No 1 hippie, biogrid 98 266 37 37 0
SF3B6 SF3B6 Q9Y3B4 Splicing factor 3B subunit 6 chr2 Not Cancer Driver No 1 hippie, biogrid 9 10 0 0 0
SHMT2 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 Not Cancer Driver No 1 hippie 57 58 5 5 1
SLC25A28 SLC25A28 Q96A46 Mitoferrin-2 chr10 Not Cancer Driver No 1 intact, hippie 43 80 0 0 0
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 Not Cancer Driver No 1 hippie 71 194 35 35 2
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 2 hippie, biogrid 10 76 7 7 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SUZ12 SUZ12 Q15022 Polycomb protein SUZ12 chr17 Census, Compendium Yes 1 hippie 83 483 46 46 3
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 Census Yes 1 hippie 54 305 53 53 0
TEAD2_ENST00000311227 TEAD2 Q15562 Transcriptional enhancer factor TEF-4 chr19 Not Cancer Driver No 1 hippie 66 220 31 31 0
TLE1 TLE1 Q04724 Transducin-like enhancer protein 1 chr9 Not Cancer Driver No 1 hippie 111 381 53 53 0
TNIK TNIK Q9UKE5 TRAF2 and NCK-interacting protein kinase chr3 Not Cancer Driver No 1 intact, hippie 254 781 156 156 0
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 Not Cancer Driver No 1 hippie 43 316 36 36 0
TOP3B_ENST00000357179 TOP3B O95985 DNA topoisomerase 3-beta-1 chr22 Not Cancer Driver No 1 hippie, biogrid 102 151 17 17 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 Not Cancer Driver No 1 intact, hippie 67 62 7 7 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
TRMT2A_ENST00000403707 TRMT2A Q8IZ69 tRNA (uracil-5-)-methyltransferase homolog A chr22 Not Cancer Driver No 1 hippie 64 157 20 20 0
TUBB3 TUBB3 Q13509 Tubulin beta-3 chain chr16 Not Cancer Driver No 1 hippie 67 53 10 10 12
U2AF1 U2AF1 Q01081 Splicing factor U2AF 35 kDa subunit chr21 Census, Compendium Yes 1 hippie, biogrid 70 73 13 13 3
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 Not Cancer Driver No 3 intact, hippie, biogrid 16 16 3 3 0
UNC119 UNC119 Q13432 Protein unc-119 homolog A chr17 Not Cancer Driver No 1 hippie 20 89 4 4 1
USP4 USP4 Q13107 Ubiquitin carboxyl-terminal hydrolase 4 chr3 Not Cancer Driver No 1 hippie 102 286 22 22 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 Not Cancer Driver No 1 hippie 188 110 28 28 0
VRK1 VRK1 Q99986 Serine/threonine-protein kinase VRK1 chr14 Not Cancer Driver No 1 hippie 52 80 9 9 0
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 30 35 3 3 0
WIZ_ENST00000263381 WIZ O95785-2 Isoform 2 of Protein Wiz chr19 Not Cancer Driver No 1 hippie 148 651 135 135 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 2 hippie, biogrid 140 33 9 9 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0
ZNF135_ENST00000313434 ZNF135 P52742 Zinc finger protein 135 chr19 Not Cancer Driver No 1 hippie 137 207 50 50 0