Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AGR2 | AGR2 | O95994 | Anterior gradient protein 2 homolog | chr7 | Not Cancer Driver | No | 1 | hippie | 23 | 20 | 2 | 2 | 0 |
ALYREF | ALYREF | Q86V81 | THO complex subunit 4 | chr17 | Not Cancer Driver | No | 1 | hippie | 32 | 223 | 26 | 26 | 0 |
ANP32A | ANP32A | P39687 | Acidic leucine-rich nuclear phosphoprotein 32 family member A | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 31 | 165 | 21 | 21 | 0 |
APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | Not Cancer Driver | No | 1 | hippie | 128 | 418 | 71 | 71 | 17 |
APTX_ENST00000379819 | APTX | Q7Z2E3 | Aprataxin | chr9 | Not Cancer Driver | No | 1 | hippie | 36 | 101 | 6 | 6 | 9 |
AQR | AQR | O60306 | RNA helicase aquarius | chr15 | Not Cancer Driver | No | 1 | hippie | 201 | 297 | 31 | 31 | 0 |
BASP1_ENST00000616743 | BASP1 | P80723 | Brain acid soluble protein 1 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 227 | 39 | 39 | 0 |
BCAP31_ENST00000345046 | BCAP31 | P51572 | B-cell receptor-associated protein 31 | chrX | Not Cancer Driver | No | 1 | hippie | 37 | 104 | 14 | 14 | 0 |
BMI1 | BMI1 | P35226 | Polycomb complex protein BMI-1 | chr10 | Not Cancer Driver | No | 1 | hippie | 50 | 150 | 30 | 30 | 0 |
BRD4 | BRD4 | O60885 | Bromodomain-containing protein 4 | chr19 | Census, Compendium | Yes | 1 | hippie | 193 | 1182 | 172 | 172 | 0 |
C17orf80_ENST00000535032 | C17orf80 | Q9BSJ5 | Uncharacterized protein C17orf80 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 455 | 53 | 53 | 0 |
C2CD5_ENST00000333957 | C2CD5 | Q86YS7 | C2 domain-containing protein 5 | chr12 | Not Cancer Driver | No | 1 | hippie | 136 | 250 | 40 | 40 | 0 |
CALM1 | CALM1 | P0DP23 | Calmodulin-1 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 115 | 15 | 15 | 7 |
CASC3 | CASC3 | O15234 | Protein CASC3 | chr17 | Not Cancer Driver | No | 6 | intact, hippie | 84 | 700 | 83 | 83 | 0 |
CCDC9 | CCDC9 | Q9Y3X0 | Coiled-coil domain-containing protein 9 | chr19 | Not Cancer Driver | No | 1 | hippie | 70 | 531 | 70 | 70 | 0 |
CDC42BPA_ENST00000334218 | CDC42BPA | Q5VT25 | Serine/threonine-protein kinase MRCK alpha | chr1 | Not Cancer Driver | No | 1 | hippie | 215 | 717 | 80 | 80 | 0 |
CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | Not Cancer Driver | No | 1 | hippie | 39 | 23 | 2 | 2 | 1 |
CHCHD1 | CHCHD1 | Q96BP2 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 67 | 8 | 8 | 0 |
CHM | CHM | P24386 | Rab proteins geranylgeranyltransferase component A 1 | chrX | Not Cancer Driver | No | 1 | hippie | 113 | 179 | 40 | 40 | 3 |
CHMP4C | CHMP4C | Q96CF2 | Charged multivesicular body protein 4c | chr8 | Not Cancer Driver | No | 1 | hippie | 33 | 224 | 31 | 31 | 0 |
CIAPIN1 | CIAPIN1 | Q6FI81 | Anamorsin | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 119 | 8 | 8 | 0 |
CLTA | CLTA | P09496 | Clathrin light chain A | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 192 | 12 | 12 | 0 |
COPS5 | COPS5 | Q92905 | COP9 signalosome complex subunit 5 | chr8 | Not Cancer Driver | No | 1 | hippie | 36 | 32 | 7 | 7 | 0 |
CTSC | CTSC | P53634 | Dipeptidyl peptidase 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 64 | 19 | 5 | 5 | 29 |
DDRGK1 | DDRGK1 | Q96HY6 | DDRGK domain-containing protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 34 | 181 | 23 | 23 | 0 |
DDX39B_ENST00000458640 | DDX39B | Q13838 | Spliceosome RNA helicase DDX39B | chr6 | Not Cancer Driver | No | 2 | hippie, biogrid | 49 | 34 | 8 | 8 | 0 |
DDX41 | DDX41 | Q9UJV9 | Probable ATP-dependent RNA helicase DDX41 | chr5 | Not Cancer Driver | No | 1 | hippie | 82 | 180 | 26 | 26 | 1 |
DHX38 | DHX38 | Q92620 | Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 139 | 622 | 83 | 83 | 1 |
DHX9 | DHX9 | Q08211 | ATP-dependent RNA helicase A | chr1 | Compendium | Yes | 1 | hippie, biogrid | 182 | 331 | 42 | 42 | 0 |
DLST | DLST | P36957 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 190 | 32 | 32 | 1 |
DNM1L_ENST00000549701 | DNM1L | O00429 | Dynamin-1-like protein | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 212 | 23 | 23 | 7 |
DOC2B | DOC2B | Q14184 | Double C2-like domain-containing protein beta | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 197 | 3 | 3 | 0 |
DPH1 | DPH1 | Q9BZG8 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 41 | 67 | 8 | 8 | 2 |
ECT2 | ECT2 | Q9H8V3 | Protein ECT2 | chr3 | Not Cancer Driver | No | 1 | hippie | 104 | 284 | 33 | 33 | 0 |
EFTUD2 | EFTUD2 | Q15029 | 116 kDa U5 small nuclear ribonucleoprotein component | chr17 | Compendium | Yes | 1 | hippie | 132 | 179 | 30 | 30 | 3 |
EHBP1L1 | EHBP1L1 | Q8N3D4 | EH domain-binding protein 1-like protein 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 127 | 1126 | 91 | 91 | 0 |
EIF4A3 | EIF4A3 | P38919 | Eukaryotic initiation factor 4A-III | chr17 | Not Cancer Driver | No | 1 | hippie | 50 | 57 | 6 | 6 | 1 |
EIF6_ENST00000374436 | EIF6 | P56537 | Eukaryotic translation initiation factor 6 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 17 | 3 | 3 | 0 |
ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | Census, Compendium | Yes | 1 | hippie | 121 | 195 | 27 | 27 | 2 |
ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | hippie | 90 | 92 | 11 | 11 | 1 |
ETF1 | ETF1 | P62495 | Eukaryotic peptide chain release factor subunit 1 | chr5 | Not Cancer Driver | No | 1 | hippie | 60 | 28 | 11 | 11 | 0 |
EWSR1_ENST00000397938 | EWSR1 | Q01844 | RNA-binding protein EWS | chr22 | Census, Compendium | Yes | 1 | hippie | 94 | 646 | 93 | 93 | 0 |
FANCD2_ENST00000383807 | FANCD2 | Q9BXW9 | Fanconi anemia group D2 protein | chr3 | Census, Compendium | Yes | 1 | hippie | 176 | 181 | 14 | 14 | 3 |
FBXO25 | FBXO25 | Q8TCJ0 | F-box only protein 25 | chr8 | Not Cancer Driver | No | 1 | hippie | 33 | 20 | 0 | 0 | 0 |
FKBP3_ENST00000396062 | FKBP3 | Q00688 | Peptidyl-prolyl cis-trans isomerase FKBP3 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 27 | 131 | 17 | 17 | 0 |
GSK3A | GSK3A | P49840 | Glycogen synthase kinase-3 alpha | chr19 | Not Cancer Driver | No | 1 | hippie | 55 | 180 | 8 | 8 | 0 |
GSPT1_ENST00000563468 | GSPT1 | P15170 | Eukaryotic peptide chain release factor GTP-binding subunit ERF3A | chr16 | Not Cancer Driver | No | 1 | hippie | 42 | 149 | 13 | 13 | 0 |
HBB | HBB | P68871 | Hemoglobin subunit beta | chr11 | Not Cancer Driver | No | 1 | hippie | 45 | 7 | 2 | 2 | 5 |
HMGA1 | HMGA1 | P17096 | High mobility group protein HMG-I/HMG-Y | chr6 | Census | Yes | 1 | hippie, biogrid | 6 | 107 | 6 | 6 | 0 |
HNRNPA1 | HNRNPA1 | P09651 | Heterogeneous nuclear ribonucleoprotein A1 | chr12 | Not Cancer Driver | No | 1 | hippie | 70 | 290 | 58 | 58 | 4 |
HNRNPC_ENST00000420743 | HNRNPC | P07910 | Heterogeneous nuclear ribonucleoproteins C1/C2 | chr14 | Not Cancer Driver | No | 1 | hippie | 42 | 227 | 35 | 35 | 0 |
HNRNPD | HNRNPD | Q14103 | Heterogeneous nuclear ribonucleoprotein D0 | chr4 | Not Cancer Driver | No | 1 | hippie | 39 | 206 | 19 | 19 | 0 |
HNRNPM | HNRNPM | P52272 | Heterogeneous nuclear ribonucleoprotein M | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 108 | 463 | 67 | 67 | 0 |
IFI16_ENST00000295809 | IFI16 | Q16666 | Gamma-interferon-inducible protein 16 | chr1 | Not Cancer Driver | No | 1 | hippie | 155 | 419 | 90 | 90 | 0 |
IKBKE | IKBKE | Q14164 | Inhibitor of nuclear factor kappa-B kinase subunit epsilon | chr1 | Not Cancer Driver | No | 1 | hippie | 108 | 76 | 13 | 13 | 0 |
IKBKG_ENST00000611071 | IKBKG | Q9Y6K9 | NF-kappa-B essential modulator | chrX | Not Cancer Driver | No | 1 | intact, hippie | 6 | 301 | 6 | 6 | 22 |
IPO13 | IPO13 | O94829 | Importin-13 | chr1 | Not Cancer Driver | No | 1 | hippie | 98 | 42 | 7 | 7 | 0 |
KAT2B | KAT2B | Q92831 | Histone acetyltransferase KAT2B | chr3 | Not Cancer Driver | No | 1 | hippie | 107 | 266 | 27 | 27 | 0 |
KIF14 | KIF14 | Q15058 | Kinesin-like protein KIF14 | chr1 | Not Cancer Driver | No | 1 | hippie | 222 | 774 | 102 | 102 | 2 |
KRAS | KRAS | P01116 | GTPase KRas | chr12 | Census, Compendium | Yes | 1 | hippie | 788 | 7 | 2 | 2 | 27 |
LSM2 | LSM2 | Q9Y333 | U6 snRNA-associated Sm-like protein LSm2 | chr6 | Not Cancer Driver | No | 2 | hippie, biogrid | 10 | 3 | 0 | 0 | 0 |
LSM3 | LSM3 | P62310 | U6 snRNA-associated Sm-like protein LSm3 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 12 | 28 | 2 | 2 | 0 |
LUC7L2 | LUC7L2 | Q9Y383 | Putative RNA-binding protein Luc7-like 2 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 59 | 262 | 45 | 45 | 0 |
LUZP4 | LUZP4 | Q9P127 | Leucine zipper protein 4 | chrX | Not Cancer Driver | No | 1 | hippie | 74 | 313 | 74 | 74 | 0 |
MAGOH | MAGOH | P61326 | Protein mago nashi homolog | chr1 | Not Cancer Driver | No | 9 | intact, hippie, biogrid | 15 | 6 | 0 | 0 | 0 |
MAGOHB | MAGOHB | Q96A72 | Protein mago nashi homolog 2 | chr12 | Not Cancer Driver | No | 3 | hippie, biogrid | 15 | 6 | 1 | 1 | 0 |
MARCKS | MARCKS | P29966 | Myristoylated alanine-rich C-kinase substrate | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 14 | 328 | 14 | 14 | 0 |
MCM7 | MCM7 | P33993 | DNA replication licensing factor MCM7 | chr7 | Not Cancer Driver | No | 1 | hippie | 101 | 128 | 22 | 22 | 0 |
MLEC | MLEC | Q14165 | Malectin | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 51 | 6 | 6 | 0 |
MTX2 | MTX2 | O75431 | Metaxin-2 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 0 | 0 | 0 | 0 |
MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
NACA_ENST00000356769 | NACA | Q13765 | Nascent polypeptide-associated complex subunit alpha | chr12 | Census | Yes | 1 | hippie, biogrid | 37 | 143 | 26 | 26 | 0 |
NCAPH2_ENST00000420993 | NCAPH2 | Q6IBW4 | Condensin-2 complex subunit H2 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 67 | 335 | 39 | 39 | 0 |
NCBP2_ENST00000427641 | NCBP2 | P52298-3 | Isoform 3 of Nuclear cap-binding protein subunit 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 21 | 61 | 9 | 9 | 0 |
NCBP3 | NCBP3 | Q53F19 | Nuclear cap-binding protein subunit 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 52 | 507 | 42 | 42 | 0 |
NEDD4 | NEDD4 | P46934 | E3 ubiquitin-protein ligase NEDD4 | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 150 | 711 | 79 | 79 | 0 |
NFX1 | NFX1 | Q12986 | Transcriptional repressor NF-X1 | chr9 | Not Cancer Driver | No | 1 | hippie | 121 | 491 | 46 | 46 | 0 |
NOP9 | NOP9 | Q86U38 | Nucleolar protein 9 | chr14 | Not Cancer Driver | No | 1 | hippie | 53 | 166 | 14 | 14 | 0 |
NPC1 | NPC1 | O15118 | NPC intracellular cholesterol transporter 1 | chr18 | Not Cancer Driver | No | 1 | hippie | 155 | 24 | 0 | 0 | 150 |
NR2C2_ENST00000393102 | NR2C2 | P49116 | Nuclear receptor subfamily 2 group C member 2 | chr3 | Not Cancer Driver | No | 1 | hippie | 62 | 186 | 24 | 24 | 0 |
NR3C1_ENST00000343796 | NR3C1 | P04150 | Glucocorticoid receptor | chr5 | Not Cancer Driver | No | 1 | hippie | 92 | 362 | 37 | 37 | 12 |
NUPR1_ENST00000324873 | NUPR1 | O60356 | Nuclear protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 10 | 82 | 10 | 10 | 0 |
NXF1_ENST00000294172 | NXF1 | Q9UBU9 | Nuclear RNA export factor 1 | chr11 | Compendium | Yes | 1 | hippie | 100 | 163 | 32 | 32 | 0 |
OBSL1 | OBSL1 | O75147 | Obscurin-like protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 233 | 553 | 60 | 60 | 0 |
ORC2 | ORC2 | Q13416 | Origin recognition complex subunit 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 67 | 248 | 22 | 22 | 0 |
P3H1_ENST00000296388 | P3H1 | Q32P28 | Prolyl 3-hydroxylase 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 91 | 177 | 18 | 18 | 0 |
P4HA1_ENST00000394890 | P4HA1 | P13674 | Prolyl 4-hydroxylase subunit alpha-1 | chr10 | Not Cancer Driver | No | 1 | hippie | 65 | 54 | 8 | 8 | 0 |
P4HB | P4HB | P07237 | Protein disulfide-isomerase | chr17 | Not Cancer Driver | No | 1 | hippie | 61 | 79 | 15 | 15 | 1 |
PABPC1 | PABPC1 | P11940 | Polyadenylate-binding protein 1 | chr8 | Census, Compendium | Yes | 1 | hippie | 100 | 317 | 55 | 55 | 0 |
PARK7_ENST00000377488 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 30 | 0 | 0 | 5 |
PCLAF | PCLAF | Q15004 | PCNA-associated factor | chr15 | Not Cancer Driver | No | 1 | hippie | 20 | 111 | 20 | 20 | 0 |
PDAP1 | PDAP1 | Q13442 | 28 kDa heat- and acid-stable phosphoprotein | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 181 | 26 | 26 | 0 |
PDHA1_ENST00000422285 | PDHA1 | P08559 | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 43 | 6 | 6 | 20 |
PDIA4 | PDIA4 | P13667 | Protein disulfide-isomerase A4 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 147 | 22 | 22 | 0 |
PEBP1 | PEBP1 | P30086 | Phosphatidylethanolamine-binding protein 1 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 76 | 13 | 13 | 0 |
PGAM1 | PGAM1 | P18669 | Phosphoglycerate mutase 1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 70 | 5 | 5 | 0 |
PGD | PGD | P52209 | 6-phosphogluconate dehydrogenase, decarboxylating | chr1 | Not Cancer Driver | No | 1 | hippie | 73 | 19 | 3 | 3 | 0 |
PKP3 | PKP3 | Q9Y446 | Plakophilin-3 | chr11 | Not Cancer Driver | No | 1 | hippie | 72 | 357 | 22 | 22 | 0 |
PPIB | PPIB | P23284 | Peptidyl-prolyl cis-trans isomerase B | chr15 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 16 | 1 | 1 | 1 |
PRC1 | PRC1 | O43663 | Protein regulator of cytokinesis 1 | chr15 | Not Cancer Driver | No | 1 | hippie | 63 | 235 | 26 | 26 | 0 |
PRKCSH_ENST00000589838 | PRKCSH | P14314 | Glucosidase 2 subunit beta | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 68 | 320 | 41 | 41 | 0 |
PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | Not Cancer Driver | No | 1 | hippie | 110 | 78 | 15 | 15 | 31 |
PSMB1 | PSMB1 | P20618 | Proteasome subunit beta type-1 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 14 | 2 | 2 | 0 |
PTMS_ENST00000309083 | PTMS | P20962 | Parathymosin | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 10 | 102 | 10 | 10 | 0 |
PUS7_ENST00000469408 | PUS7 | Q96PZ0 | Pseudouridylate synthase 7 homolog | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 73 | 162 | 17 | 17 | 1 |
PYM1 | PYM1 | Q9BRP8 | Partner of Y14 and mago | chr12 | Not Cancer Driver | No | 2 | intact, hippie | 22 | 204 | 22 | 22 | 0 |
R3HCC1L | R3HCC1L | Q7Z5L2 | Coiled-coil domain-containing protein R3HCC1L | chr10 | Not Cancer Driver | No | 1 | hippie | 103 | 493 | 57 | 57 | 0 |
RAD18 | RAD18 | Q9NS91 | E3 ubiquitin-protein ligase RAD18 | chr3 | Not Cancer Driver | No | 1 | hippie | 59 | 328 | 43 | 43 | 0 |
RAD23B | RAD23B | P54727 | UV excision repair protein RAD23 homolog B | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 324 | 41 | 41 | 0 |
RAE1_ENST00000371242 | RAE1 | P78406 | mRNA export factor RAE1 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 73 | 11 | 11 | 0 |
RBM14 | RBM14 | Q96PK6 | RNA-binding protein 14 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 99 | 350 | 59 | 59 | 0 |
RBM39 | RBM39 | Q14498 | RNA-binding protein 39 | chr20 | Compendium | Yes | 1 | hippie | 81 | 228 | 39 | 39 | 0 |
RBM3_ENST00000376755 | RBM3 | P98179 | RNA-binding protein 3 | chrX | Not Cancer Driver | No | 1 | hippie | 22 | 134 | 18 | 18 | 0 |
RBM8A_ENST00000632555 | RBM8A | Q9Y5S9 | RNA-binding protein 8A | chr1 | Not Cancer Driver | No | 1 | hippie | 35 | 135 | 32 | 32 | 0 |
RBMX | RBMX | P38159 | RNA-binding motif protein, X chromosome | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 82 | 380 | 81 | 81 | 0 |
RECQL4 | RECQL4 | O94761 | ATP-dependent DNA helicase Q4 | chr8 | Census, Compendium | Yes | 1 | hippie | 138 | 608 | 71 | 71 | 1 |
RHOBTB2_ENST00000251822 | RHOBTB2 | Q9BYZ6 | Rho-related BTB domain-containing protein 2 | chr8 | Not Cancer Driver | No | 1 | hippie | 99 | 131 | 18 | 18 | 6 |
RNF113A | RNF113A | O15541 | E3 ubiquitin-protein ligase RNF113A | chrX | Not Cancer Driver | No | 1 | hippie | 61 | 226 | 51 | 51 | 0 |
RNF2 | RNF2 | Q99496 | E3 ubiquitin-protein ligase RING2 | chr1 | Not Cancer Driver | No | 1 | hippie | 40 | 203 | 22 | 22 | 0 |
RNPS1_ENST00000301730 | RNPS1 | Q15287 | RNA-binding protein with serine-rich domain 1 | chr16 | Not Cancer Driver | No | 2 | hippie, biogrid | 30 | 305 | 30 | 30 | 0 |
RPGRIP1 | RPGRIP1 | Q96KN7 | X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 219 | 680 | 110 | 110 | 6 |
RPL11 | RPL11 | P62913 | 60S ribosomal protein L11 | chr1 | Not Cancer Driver | No | 1 | hippie | 27 | 12 | 1 | 1 | 1 |
RPS16 | RPS16 | P62249 | 40S ribosomal protein S16 | chr19 | Not Cancer Driver | No | 1 | hippie | 16 | 14 | 1 | 1 | 0 |
RPSA_ENST00000301821 | RPSA | P08865 | 40S ribosomal protein SA | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 22 | 95 | 6 | 6 | 5 |
RRBP1_ENST00000246043 | RRBP1 | Q9P2E9 | Ribosome-binding protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 164 | 1301 | 151 | 151 | 0 |
RUVBL1 | RUVBL1 | Q9Y265 | RuvB-like 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 54 | 67 | 7 | 7 | 0 |
RUVBL2 | RUVBL2 | Q9Y230 | RuvB-like 2 | chr19 | Not Cancer Driver | No | 1 | hippie | 62 | 100 | 13 | 13 | 0 |
SCYL2_ENST00000360820 | SCYL2 | Q6P3W7 | SCY1-like protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 103 | 328 | 29 | 29 | 0 |
SDE2 | SDE2 | Q6IQ49 | Replication stress response regulator SDE2 | chr1 | Not Cancer Driver | No | 1 | hippie | 56 | 290 | 35 | 35 | 0 |
SEPHS2 | SEPHS2 | Q99611 | Selenide, water dikinase 2 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 104 | 2 | 2 | 0 |
SF3B2 | SF3B2 | Q13435 | Splicing factor 3B subunit 2 | chr11 | Not Cancer Driver | No | 1 | hippie | 110 | 804 | 105 | 105 | 0 |
SLIRP | SLIRP | Q9GZT3 | SRA stem-loop-interacting RNA-binding protein, mitochondrial | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 7 | 41 | 3 | 3 | 0 |
SLK | SLK | Q9H2G2 | STE20-like serine/threonine-protein kinase | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 134 | 962 | 96 | 96 | 0 |
SLU7 | SLU7 | O95391 | Pre-mRNA-splicing factor SLU7 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 75 | 436 | 63 | 63 | 0 |
SMG1 | SMG1 | Q96Q15 | Serine/threonine-protein kinase SMG1 | chr16 | Not Cancer Driver | No | 1 | hippie | 348 | 605 | 73 | 73 | 0 |
SMG5 | SMG5 | Q9UPR3 | Nonsense-mediated mRNA decay factor SMG5 | chr1 | Not Cancer Driver | No | 1 | hippie | 132 | 295 | 51 | 51 | 0 |
SMG6 | SMG6 | Q86US8 | Telomerase-binding protein EST1A | chr17 | Not Cancer Driver | No | 1 | hippie | 166 | 751 | 97 | 97 | 0 |
SMG7_ENST00000347615 | SMG7 | Q92540 | Nonsense-mediated mRNA decay factor SMG7 | chr1 | Not Cancer Driver | No | 1 | hippie | 134 | 664 | 82 | 82 | 0 |
SMG8_ENST00000300917 | SMG8 | Q8ND04 | Nonsense-mediated mRNA decay factor SMG8 | chr17 | Not Cancer Driver | No | 1 | hippie | 145 | 412 | 57 | 57 | 1 |
SMG9 | SMG9 | Q9H0W8 | Nonsense-mediated mRNA decay factor SMG9 | chr19 | Not Cancer Driver | No | 1 | hippie | 43 | 256 | 23 | 23 | 0 |
SNIP1 | SNIP1 | Q8TAD8 | Smad nuclear-interacting protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 58 | 285 | 40 | 40 | 1 |
SNRNP70 | SNRNP70 | P08621 | U1 small nuclear ribonucleoprotein 70 kDa | chr19 | Not Cancer Driver | No | 1 | hippie | 38 | 416 | 37 | 37 | 0 |
SNRPF | SNRPF | P62306 | Small nuclear ribonucleoprotein F | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 4 | 10 | 0 | 0 | 0 |
SOD1 | SOD1 | P00441 | Superoxide dismutase [Cu-Zn] | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 93 | 9 | 9 | 79 |
SPTBN1 | SPTBN1 | Q01082 | Spectrin beta chain, non-erythrocytic 1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 311 | 869 | 123 | 123 | 0 |
SRPK1 | SRPK1 | Q96SB4 | SRSF protein kinase 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 73 | 329 | 32 | 32 | 0 |
SRPK2_ENST00000489828 | SRPK2 | P78362 | SRSF protein kinase 2 | chr7 | Not Cancer Driver | No | 1 | hippie | 78 | 343 | 46 | 46 | 0 |
SRRM1 | SRRM1 | Q8IYB3 | Serine/arginine repetitive matrix protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 129 | 795 | 122 | 122 | 0 |
SRRM2 | SRRM2 | Q9UQ35 | Serine/arginine repetitive matrix protein 2 | chr16 | Not Cancer Driver | No | 2 | hippie, biogrid | 433 | 2748 | 431 | 431 | 0 |
SRSF1 | SRSF1 | Q07955 | Serine/arginine-rich splicing factor 1 | chr17 | Not Cancer Driver | No | 1 | hippie | 41 | 198 | 34 | 34 | 0 |
SRSF3_ENST00000620941 | SRSF3 | P84103 | Serine/arginine-rich splicing factor 3 | chr6 | Census | Yes | 1 | hippie | 31 | 125 | 27 | 27 | 0 |
STAT3 | STAT3 | P40763 | Signal transducer and activator of transcription 3 | chr17 | Census, Compendium | Yes | 1 | hippie | 110 | 152 | 15 | 15 | 19 |
STMN1_ENST00000357865 | STMN1 | P16949 | Stathmin | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 149 | 15 | 15 | 0 |
SUMO2 | SUMO2 | P61956 | Small ubiquitin-related modifier 2 | chr17 | Not Cancer Driver | No | 2 | hippie, biogrid | 9 | 69 | 6 | 6 | 0 |
SUZ12 | SUZ12 | Q15022 | Polycomb protein SUZ12 | chr17 | Census, Compendium | Yes | 1 | hippie | 83 | 483 | 46 | 46 | 3 |
TCF12_ENST00000267811 | TCF12 | Q99081 | Transcription factor 12 | chr15 | Census | Yes | 1 | hippie | 105 | 680 | 105 | 105 | 3 |
TDRD3_ENST00000196169 | TDRD3 | Q9H7E2 | Tudor domain-containing protein 3 | chr13 | Not Cancer Driver | No | 1 | hippie | 97 | 518 | 77 | 77 | 0 |
TFCP2L1 | TFCP2L1 | Q9NZI6 | Transcription factor CP2-like protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 59 | 141 | 23 | 23 | 0 |
THOC7 | THOC7 | Q6I9Y2 | THO complex subunit 7 homolog | chr3 | Not Cancer Driver | No | 1 | hippie | 26 | 63 | 5 | 5 | 0 |
THRAP3_ENST00000469141 | THRAP3 | Q9Y2W1 | Thyroid hormone receptor-associated protein 3 | chr1 | Census | Yes | 1 | hippie | 137 | 955 | 137 | 137 | 0 |
TKT_ENST00000462138 | TKT | P29401 | Transketolase | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 66 | 86 | 7 | 7 | 1 |
TMEM263_ENST00000551813 | TMEM263 | Q8WUH6 | Transmembrane protein 263 | chr12 | Not Cancer Driver | No | 1 | hippie | 6 | 63 | 3 | 3 | 0 |
TNIP2 | TNIP2 | Q8NFZ5 | TNFAIP3-interacting protein 2 | chr4 | Not Cancer Driver | No | 1 | hippie | 43 | 316 | 36 | 36 | 0 |
TOE1 | TOE1 | Q96GM8 | Target of EGR1 protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie | 44 | 210 | 22 | 22 | 10 |
TPM3 | TPM3 | P06753 | Tropomyosin alpha-3 chain | chr1 | Census | Yes | 1 | hippie, biogrid | 35 | 230 | 27 | 27 | 21 |
TRIM14 | TRIM14 | Q14142 | Tripartite motif-containing protein 14 | chr9 | Not Cancer Driver | No | 1 | hippie | 36 | 93 | 7 | 7 | 0 |
TTI1 | TTI1 | O43156 | TELO2-interacting protein 1 homolog | chr20 | Not Cancer Driver | No | 1 | hippie | 136 | 93 | 13 | 13 | 0 |
UBE2M | UBE2M | P61081 | NEDD8-conjugating enzyme Ubc12 | chr19 | Not Cancer Driver | No | 1 | hippie | 30 | 32 | 6 | 6 | 0 |
UFL1 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 109 | 141 | 24 | 24 | 0 |
UNC119B | UNC119B | A6NIH7 | Protein unc-119 homolog B | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 35 | 71 | 4 | 4 | 0 |
UPF1 | UPF1 | Q92900 | Regulator of nonsense transcripts 1 | chr19 | Not Cancer Driver | No | 2 | intact, hippie | 146 | 329 | 36 | 36 | 0 |
UPF2_ENST00000357604 | UPF2 | Q9HAU5 | Regulator of nonsense transcripts 2 | chr10 | Not Cancer Driver | No | 1 | hippie | 150 | 632 | 84 | 84 | 0 |
UPF3A | UPF3A | Q9H1J1 | Regulator of nonsense transcripts 3A | chr13 | Not Cancer Driver | No | 1 | hippie | 31 | 378 | 21 | 21 | 0 |
UPF3B | UPF3B | Q9BZI7 | Regulator of nonsense transcripts 3B | chrX | Not Cancer Driver | No | 1 | hippie | 98 | 428 | 91 | 91 | 1 |
USP21_ENST00000289865 | USP21 | Q9UK80 | Ubiquitin carboxyl-terminal hydrolase 21 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 95 | 230 | 47 | 47 | 0 |
UTRN | UTRN | P46939 | Utrophin | chr6 | Not Cancer Driver | No | 1 | hippie | 476 | 1283 | 183 | 183 | 0 |
VCP | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | Not Cancer Driver | No | 1 | hippie | 88 | 186 | 16 | 16 | 16 |
ZBTB2 | ZBTB2 | Q8N680 | Zinc finger and BTB domain-containing protein 2 | chr6 | Not Cancer Driver | No | 1 | hippie | 75 | 216 | 30 | 30 | 0 |
ZC3H18_ENST00000301011 | ZC3H18 | Q86VM9 | Zinc finger CCCH domain-containing protein 18 | chr16 | Not Cancer Driver | No | 1 | hippie | 139 | 929 | 134 | 134 | 0 |
ZFP36L1 | ZFP36L1 | Q07352 | mRNA decay activator protein ZFP36L1 | chr14 | Compendium | Yes | 1 | hippie | 57 | 212 | 30 | 30 | 0 |
ZMYND8_ENST00000311275 | ZMYND8 | Q9ULU4 | Protein kinase C-binding protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 176 | 830 | 124 | 124 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
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