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RBBP4 ,RBBP4 ,Q09028
  • Uniprot Accession= Q09028
  • Ensembl Transcript= ENST00000373493.9
  • Uniprot Name= RBBP4
  • Name= Histone-binding protein RBBP4
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 23
  • Number of Interaction partner in biogrid: 137
  • Number of Interaction partner in hippie: 386
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 51 6 2 2 0
AEBP2 AEBP2 Q6ZN18 Zinc finger protein AEBP2 chr12 Not Cancer Driver No 3 hippie, biogrid 41 335 25 25 0
ALB ALB P02768 Albumin chr4 Compendium Yes 1 hippie 162 6 0 0 3
ALDH4A1 ALDH4A1 P30038 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial chr1 Not Cancer Driver No 1 hippie 63 46 9 9 1
ANG ANG P03950 Angiogenin chr14 Not Cancer Driver No 1 hippie 19 36 2 2 14
ANKRD27 ANKRD27 Q96NW4 Ankyrin repeat domain-containing protein 27 chr19 Not Cancer Driver No 1 hippie 145 239 33 33 0
ANXA7 ANXA7 P20073 Annexin A7 chr10 Not Cancer Driver No 1 hippie 68 215 37 37 0
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 hippie 128 418 71 71 17
APPL1 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 Not Cancer Driver No 1 hippie 67 292 31 31 1
ARID4A ARID4A P29374 AT-rich interactive domain-containing protein 4A chr14 Not Cancer Driver No 2 hippie, biogrid 151 978 123 123 0
ARID4B ARID4B Q4LE39 AT-rich interactive domain-containing protein 4B chr1 Not Cancer Driver No 2 hippie, biogrid 143 1005 118 118 0
ARIH2 ARIH2 O95376 E3 ubiquitin-protein ligase ARIH2 chr3 Not Cancer Driver No 1 hippie 64 85 11 11 0
ARMC12_ENST00000373866 ARMC12 Q5T9G4 Armadillo repeat-containing protein 12 chr6 Not Cancer Driver No 1 hippie 58 8 0 0 0
ASF1A ASF1A Q9Y294 Histone chaperone ASF1A chr6 Not Cancer Driver No 3 hippie, biogrid 18 69 2 2 0
ASF1B ASF1B Q9NVP2 Histone chaperone ASF1B chr19 Not Cancer Driver No 3 hippie, biogrid 30 23 7 7 0
ASH1L_ENST00000368346 ASH1L Q9NR48 Histone-lysine N-methyltransferase ASH1L chr1 Not Cancer Driver No 1 hippie, biogrid 415 1858 256 256 1
ASXL1_ENST00000613218 ASXL1 Q8IXJ9 Polycomb group protein ASXL1 chr20 Census, Compendium Yes 1 hippie 205 1300 174 174 0
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 79 239 25 25 1
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 Not Cancer Driver No 1 hippie 40 25 6 6 1
ATP6V1A ATP6V1A P38606 V-type proton ATPase catalytic subunit A chr3 Not Cancer Driver No 1 hippie 86 31 2 2 4
ATXN1 ATXN1 P54253 Ataxin-1 chr6 Not Cancer Driver No 1 hippie 193 604 168 168 0
ATXN3 ATXN3 P54252 Ataxin-3 chr14 Not Cancer Driver No 1 hippie 46 181 24 24 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 Not Cancer Driver No 1 hippie 14 163 14 14 0
BAG1 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 Not Cancer Driver No 1 biogrid 29 195 9 9 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 Not Cancer Driver No 1 hippie 57 571 57 57 7
BAHCC1 BAHCC1 Q9P281 BAH and coiled-coil domain-containing protein 1 chr17 Not Cancer Driver No 1 hippie, biogrid 180 2253 142 142 0
BANF1_ENST00000445560 BANF1 O75531 Barrier-to-autointegration factor chr11 Not Cancer Driver No 1 hippie 10 11 2 2 1
BAP1 BAP1 Q92560 Ubiquitin carboxyl-terminal hydrolase BAP1 chr3 Census, Compendium Yes 1 hippie 141 418 59 59 0
BAZ1A_ENST00000382422 BAZ1A Q9NRL2 Bromodomain adjacent to zinc finger domain protein 1A chr14 Census Yes 1 hippie, biogrid 156 752 65 65 0
BCL11A BCL11A Q9H165 B-cell lymphoma/leukemia 11A chr2 Census, Compendium Yes 3 hippie, biogrid 210 677 171 171 3
BCL11B BCL11B Q9C0K0 B-cell lymphoma/leukemia 11B chr14 Census, Compendium Yes 2 hippie, biogrid 156 699 114 114 2
BCL2L14 BCL2L14 Q9BZR8 Apoptosis facilitator Bcl-2-like protein 14 chr12 Not Cancer Driver No 1 hippie 29 40 4 4 0
BCOR BCOR Q6W2J9 BCL-6 corepressor chrX Census, Compendium Yes 1 hippie 291 1285 226 226 1
BEND7 BEND7 Q8N7W2-3 Isoform 3 of BEN domain-containing protein 7 chr10 Not Cancer Driver No 2 hippie, biogrid 64 305 32 32 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BPTF_ENST00000321892 BPTF Q12830 Nucleosome-remodeling factor subunit BPTF chr17 Not Cancer Driver No 3 hippie, biogrid 309 2187 218 218 2
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 1 hippie 224 1458 174 174 35
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 Census, Compendium Yes 1 hippie 193 1182 172 172 0
BRD7_ENST00000394688 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 Compendium Yes 1 hippie 82 482 57 57 0
BRMS1L BRMS1L Q5PSV4 Breast cancer metastasis-suppressor 1-like protein chr14 Not Cancer Driver No 3 hippie, biogrid 35 160 17 17 0
BRMS1_ENST00000359957 BRMS1 Q9HCU9 Breast cancer metastasis-suppressor 1 chr11 Not Cancer Driver No 2 hippie, biogrid 42 115 18 18 0
BTF3 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie 27 192 24 24 0
CABIN1 CABIN1 Q9Y6J0 Calcineurin-binding protein cabin-1 chr22 Not Cancer Driver No 1 hippie, biogrid 225 1008 95 95 0
CASP6 CASP6 P55212 Caspase-6 chr4 Not Cancer Driver No 1 hippie 28 24 4 4 0
CBX1_ENST00000225603 CBX1 P83916 Chromobox protein homolog 1 chr17 Not Cancer Driver No 2 hippie, biogrid 31 154 25 25 0
CBX3_ENST00000396386 CBX3 Q13185 Chromobox protein homolog 3 chr7 Not Cancer Driver No 1 hippie 23 119 18 18 0
CBX5 CBX5 P45973 Chromobox protein homolog 5 chr12 Not Cancer Driver No 2 hippie, biogrid 21 116 12 12 0
CCDC8 CCDC8 Q9H0W5 Coiled-coil domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie, biogrid 96 505 91 91 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 Census, Compendium Yes 1 hippie 55 31 25 25 0
CD81 CD81 P60033 CD81 antigen chr11 Not Cancer Driver No 1 hippie 28 0 0 0 0
CDC5L CDC5L Q99459 Cell division cycle 5-like protein chr6 Not Cancer Driver No 1 hippie 100 618 77 77 0
CDCA5 CDCA5 Q96FF9 Sororin chr11 Not Cancer Driver No 1 hippie 32 211 26 26 0
CDK20 CDK20 Q8IZL9 Cyclin-dependent kinase 20 chr9 Not Cancer Driver No 1 hippie 36 32 1 1 0
CDK2AP1 CDK2AP1 O14519 Cyclin-dependent kinase 2-associated protein 1 chr12 Not Cancer Driver No 3 hippie, biogrid 10 76 8 8 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 Census, Compendium Yes 1 hippie 48 121 30 30 0
CDYL_ENST00000328908 CDYL Q9Y232 Chromodomain Y-like protein chr6 Not Cancer Driver No 1 hippie 99 346 61 61 0
CENPA CENPA P49450 Histone H3-like centromeric protein A chr2 Not Cancer Driver No 2 hippie, biogrid 15 50 4 4 0
CEP250 CEP250 Q9BV73 Centrosome-associated protein CEP250 chr20 Not Cancer Driver No 1 hippie 250 1859 195 195 0
CEP76 CEP76 Q8TAP6 Centrosomal protein of 76 kDa chr18 Not Cancer Driver No 1 hippie 63 96 7 7 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 Not Cancer Driver No 1 hippie 287 145 18 18 151
CHAF1A CHAF1A Q13111 Chromatin assembly factor 1 subunit A chr19 Not Cancer Driver No 3 hippie, biogrid 133 767 99 99 0
CHAF1B CHAF1B Q13112 Chromatin assembly factor 1 subunit B chr21 Not Cancer Driver No 3 hippie, biogrid 65 186 30 30 0
CHAMP1 CHAMP1 Q96JM3 Chromosome alignment-maintaining phosphoprotein 1 chr13 Not Cancer Driver No 1 hippie, biogrid 85 624 65 65 0
CHD3_ENST00000330494 CHD3 Q12873 Chromodomain-helicase-DNA-binding protein 3 chr17 Not Cancer Driver No 4 hippie, biogrid 235 1015 122 122 18
CHD4 CHD4 Q14839 Chromodomain-helicase-DNA-binding protein 4 chr12 Census, Compendium Yes 5 hippie, biogrid 419 974 177 177 6
CHD5 CHD5 Q8TDI0 Chromodomain-helicase-DNA-binding protein 5 chr1 Not Cancer Driver No 2 hippie, biogrid 365 931 183 183 0
CHD7 CHD7 Q9P2D1 Chromodomain-helicase-DNA-binding protein 7 chr8 Not Cancer Driver No 1 hippie, biogrid 464 1872 299 299 50
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 Not Cancer Driver No 1 hippie 25 201 22 22 2
CHRNA7_ENST00000306901 CHRNA7 P36544 Neuronal acetylcholine receptor subunit alpha-7 chr15 Not Cancer Driver No 1 hippie 71 18 4 4 0
CIC CIC Q96RK0 Protein capicua homolog chr19 Census, Compendium Yes 1 hippie 276 1550 266 266 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CLSTN1 CLSTN1 O94985 Calsyntenin-1 chr1 Not Cancer Driver No 1 hippie 110 271 22 22 0
COX15 COX15 Q7KZN9 Cytochrome c oxidase assembly protein COX15 homolog chr10 Not Cancer Driver No 1 hippie, biogrid 48 0 0 0 2
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 Census Yes 1 hippie 25 277 23 23 0
CREBBP CREBBP Q92793 CREB-binding protein chr16 Census, Compendium Yes 1 hippie 412 1796 247 247 33
CSNK2A1_ENST00000400217 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 Not Cancer Driver No 1 hippie, biogrid 71 75 8 8 4
CTBP1 CTBP1 Q13363 C-terminal-binding protein 1 chr4 Not Cancer Driver No 1 hippie 42 123 9 9 1
CUL4A CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 hippie 64 102 2 2 0
CUL4B CUL4B Q13620 Cullin-4B chrX Not Cancer Driver No 1 hippie 138 207 38 38 2
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 2 hippie, biogrid 188 372 41 41 3
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 Census, Compendium Yes 1 hippie 116 213 31 31 3
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 Not Cancer Driver No 1 hippie 102 485 61 61 4
DCPS DCPS Q96C86 m7GpppX diphosphatase chr11 Not Cancer Driver No 1 hippie 48 53 6 6 1
DCTN2_ENST00000548249 DCTN2 Q13561 Dynactin subunit 2 chr12 Not Cancer Driver No 1 hippie, biogrid 46 253 32 32 0
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 Not Cancer Driver No 1 hippie 34 181 23 23 0
DDX39B_ENST00000458640 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 Not Cancer Driver No 1 hippie 49 34 8 8 0
DHFR2_ENST00000314636 DHFR2 Q86XF0 Dihydrofolate reductase 2, mitochondrial chr3 Not Cancer Driver No 1 hippie 25 20 0 0 0
DHX30 DHX30 Q7L2E3 ATP-dependent RNA helicase DHX30 chr3 Not Cancer Driver No 1 hippie 165 260 40 40 6
DLD DLD P09622 Dihydrolipoyl dehydrogenase, mitochondrial chr7 Not Cancer Driver No 1 hippie, biogrid 67 17 0 0 10
DNAJB13 DNAJB13 P59910 DnaJ homolog subfamily B member 13 chr11 Not Cancer Driver No 1 hippie, biogrid 57 42 14 14 1
DNAJB6 DNAJB6 O75190 DnaJ homolog subfamily B member 6 chr7 Not Cancer Driver No 1 hippie, biogrid 33 198 17 17 3
DNAJC12 DNAJC12 Q9UKB3 DnaJ homolog subfamily C member 12 chr10 Not Cancer Driver No 1 hippie, biogrid 29 124 17 17 1
DNAJC8 DNAJC8 O75937 DnaJ homolog subfamily C member 8 chr1 Not Cancer Driver No 1 hippie, biogrid 29 188 23 23 0
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 Not Cancer Driver No 1 hippie, biogrid 67 212 23 23 7
DNMT1_ENST00000340748 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 Not Cancer Driver No 1 hippie 203 702 78 78 4
DNMT3B DNMT3B Q9UBC3 DNA (cytosine-5)-methyltransferase 3B chr20 Not Cancer Driver No 1 hippie 153 328 71 71 16
DPY30 DPY30 Q9C005 Protein dpy-30 homolog chr2 Not Cancer Driver No 1 hippie 10 57 6 6 0
DSN1 DSN1 Q9H410 Kinetochore-associated protein DSN1 homolog chr20 Not Cancer Driver No 1 hippie, biogrid 45 191 28 28 0
DYRK4_ENST00000010132 DYRK4 Q9NR20 Dual specificity tyrosine-phosphorylation-regulated kinase 4 chr12 Not Cancer Driver No 1 hippie 111 178 33 33 0
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 Not Cancer Driver No 1 hippie 49 272 23 23 0
E2F4 E2F4 Q16254 Transcription factor E2F4 chr16 Not Cancer Driver No 1 hippie, biogrid 44 242 32 32 0
EAF2 EAF2 Q96CJ1 ELL-associated factor 2 chr3 Not Cancer Driver No 1 hippie 31 199 22 22 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 104 284 33 33 0
EED_ENST00000263360 EED O75530 Polycomb protein EED chr11 Census Yes 4 intact, hippie, biogrid 64 79 11 11 6
EIF1B EIF1B O60739 Eukaryotic translation initiation factor 1b chr3 Not Cancer Driver No 1 hippie 12 6 0 0 0
ELAVL1 ELAVL1 Q15717 ELAV-like protein 1 chr19 Not Cancer Driver No 1 hippie 69 43 5 5 0
EMSY_ENST00000529032 EMSY Q7Z589 BRCA2-interacting transcriptional repressor EMSY chr11 Not Cancer Driver No 1 hippie 166 1151 147 147 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 Census, Compendium Yes 1 hippie 334 1790 196 196 1
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 Not Cancer Driver No 1 hippie, biogrid 211 829 117 117 9
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 hippie 121 195 27 27 2
EXOSC8 EXOSC8 Q96B26 Exosome complex component RRP43 chr13 Not Cancer Driver No 1 hippie 20 28 1 1 2
EZH1 EZH1 Q92800 Histone-lysine N-methyltransferase EZH1 chr17 Not Cancer Driver No 3 hippie, biogrid 82 213 21 21 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 Census, Compendium Yes 3 hippie, biogrid 120 284 44 44 11
FAM43A FAM43A Q8N2R8 Protein FAM43A chr3 Not Cancer Driver No 1 hippie, biogrid 29 222 14 14 0
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie 176 181 14 14 3
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 Not Cancer Driver No 1 hippie 75 243 38 38 1
FBXW8 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 Not Cancer Driver No 1 hippie, biogrid 68 120 4 4 0
FLNA FLNA P21333 Filamin-A chrX Census Yes 1 hippie 416 1456 214 214 28
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 hippie 394 1243 185 185 8
FOXA1 FOXA1 P55317 Hepatocyte nuclear factor 3-alpha chr14 Census, Compendium Yes 1 hippie 100 295 53 53 0
FOXK2 FOXK2 Q01167 Forkhead box protein K2 chr17 Not Cancer Driver No 1 hippie 79 548 64 64 0
FTSJ1 FTSJ1 Q9UET6 Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase chrX Not Cancer Driver No 1 hippie 44 89 14 14 0
FUS FUS P35637 RNA-binding protein FUS chr16 Census Yes 1 hippie 51 524 51 51 20
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 Not Cancer Driver No 1 hippie 74 184 30 30 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 Not Cancer Driver No 1 hippie 85 352 65 65 0
GABARAP GABARAP O95166 Gamma-aminobutyric acid receptor-associated protein chr17 Not Cancer Driver No 1 hippie 9 11 0 0 0
GABARAPL1_ENST00000545887 GABARAPL1 Q9H0R8 Gamma-aminobutyric acid receptor-associated protein-like 1 chr12 Not Cancer Driver No 1 hippie 19 10 1 1 0
GABARAPL2 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 Not Cancer Driver No 1 hippie 11 2 1 1 0
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 Census, Compendium Yes 1 hippie 111 364 87 87 2
GATAD1 GATAD1 Q8WUU5 GATA zinc finger domain-containing protein 1 chr7 Not Cancer Driver No 3 hippie, biogrid 14 131 4 4 1
GATAD2A_ENST00000360315 GATAD2A Q86YP4 Transcriptional repressor p66-alpha chr19 Not Cancer Driver No 5 hippie, biogrid 88 548 77 77 0
GATAD2B_ENST00000634544 GATAD2B Q8WXI9 Transcriptional repressor p66-beta chr1 Not Cancer Driver No 4 intact, hippie, biogrid 76 510 67 67 0
GEMIN5 GEMIN5 Q8TEQ6 Gem-associated protein 5 chr5 Not Cancer Driver No 1 biogrid 157 419 54 54 5
GNL3 GNL3 Q9BVP2 Guanine nucleotide-binding protein-like 3 chr3 Not Cancer Driver No 1 hippie, biogrid 56 257 21 21 0
HAT1 HAT1 O14929 Histone acetyltransferase type B catalytic subunit chr2 Not Cancer Driver No 4 hippie, biogrid 51 14 2 2 0
HCFC1 HCFC1 P51610 Host cell factor 1 chrX Not Cancer Driver No 1 hippie 280 1345 181 181 1
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 8 intact, hippie, biogrid 47 135 10 10 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 5 hippie, biogrid 46 145 14 14 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 Not Cancer Driver No 1 hippie 65 61 8 8 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 1 hippie 182 749 132 132 0
HDAC5_ENST00000586802 HDAC5 Q9UQL6 Histone deacetylase 5 chr17 Not Cancer Driver No 1 hippie 118 718 73 73 0
HDGF_ENST00000357325 HDGF P51858 Hepatoma-derived growth factor chr1 Not Cancer Driver No 1 hippie 35 203 29 29 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 Not Cancer Driver No 1 hippie 40 352 40 40 0
HIC1 HIC1 Q14526 Hypermethylated in cancer 1 protein chr17 Not Cancer Driver No 1 hippie 24 361 6 6 0
HIP1 HIP1 O00291 Huntingtin-interacting protein 1 chr7 Census, Compendium Yes 1 hippie 137 510 70 70 0
HIPK4 HIPK4 Q8NE63 Homeodomain-interacting protein kinase 4 chr19 Not Cancer Driver No 1 hippie 87 258 23 23 0
HIRA HIRA P54198 Protein HIRA chr22 Not Cancer Driver No 1 hippie, biogrid 138 288 37 37 0
HIST1H4A H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 15 31 5 5 0
HIST1H4B H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 29 31 6 6 0
HIST1H4C H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 29 31 7 7 0
HIST1H4D H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 32 31 8 8 0
HIST1H4E H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 45 31 14 14 0
HIST1H4F H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 30 31 7 7 0
HIST1H4H H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 22 31 9 9 0
HIST1H4I H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 33 31 10 10 0
HIST1H4J H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 26 31 9 9 0
HIST1H4K H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 44 31 13 13 0
HIST1H4L H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 25 31 14 14 0
HIST4H4 H4-16 P62805 Histone H4 chr12 Not Cancer Driver No 1 intact 21 31 7 7 0
HJURP HJURP Q8NCD3 Holliday junction recognition protein chr2 Not Cancer Driver No 3 hippie, biogrid 108 572 85 85 0
HLA-B HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 Compendium Yes 1 hippie 78 169 34 34 0
HMGXB4 HMGXB4 Q9UGU5 HMG domain-containing protein 4 chr22 Not Cancer Driver No 3 hippie, biogrid 68 475 56 56 0
HMOX2_ENST00000406590 HMOX2 P30519 Heme oxygenase 2 chr16 Not Cancer Driver No 1 hippie 27 74 10 10 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie 669 2091 329 329 21
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 Not Cancer Driver No 1 hippie 155 419 90 90 0
IGSF8_ENST00000614243 IGSF8 Q969P0 Immunoglobulin superfamily member 8 chr1 Not Cancer Driver No 1 hippie 93 207 32 32 0
IKZF1 IKZF1 Q13422 DNA-binding protein Ikaros chr7 Census, Compendium Yes 1 hippie 143 326 92 92 5
IKZF3 IKZF3 Q9UKT9 Zinc finger protein Aiolos chr17 Census, Compendium Yes 1 hippie 106 284 60 60 1
ING1 ING1 Q9UK53 Inhibitor of growth protein 1 chr13 Compendium Yes 2 hippie, biogrid 69 209 33 33 3
ING2 ING2 Q9H160 Inhibitor of growth protein 2 chr4 Not Cancer Driver No 2 hippie, biogrid 33 169 26 26 0
IRAK2 IRAK2 O43187 Interleukin-1 receptor-associated kinase-like 2 chr3 Not Cancer Driver No 1 hippie 84 202 32 32 0
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 Not Cancer Driver No 1 hippie 12 24 2 2 0
ITFG1 ITFG1 Q8TB96 T-cell immunomodulatory protein chr16 Not Cancer Driver No 1 hippie 70 18 3 3 0
ITSN1 ITSN1 Q15811 Intersectin-1 chr21 Not Cancer Driver No 1 hippie, biogrid 214 797 107 107 0
JARID2 JARID2 Q92833 Protein Jumonji chr6 Not Cancer Driver No 2 hippie, biogrid 190 724 113 113 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 Not Cancer Driver No 1 hippie 67 291 28 28 3
KDM5A KDM5A P29375 Lysine-specific demethylase 5A chr12 Census, Compendium Yes 1 hippie, biogrid 220 503 66 66 0
KDM5B_ENST00000367265 KDM5B Q9UGL1 Lysine-specific demethylase 5B chr1 Not Cancer Driver No 1 hippie 219 388 58 58 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
KIF20A KIF20A O95235 Kinesin-like protein KIF20A chr5 Not Cancer Driver No 1 hippie 79 340 40 40 1
KMT2A_ENST00000389506 KMT2A Q03164 Histone-lysine N-methyltransferase 2A chr11 Census, Compendium Yes 1 hippie 446 3145 338 338 0
KMT2E KMT2E Q8IZD2 Inactive histone-lysine N-methyltransferase 2E chr7 Not Cancer Driver No 1 hippie 233 1613 198 198 4
KMT5A KMT5A Q9NQR1-2 Isoform 2 of N-lysine methyltransferase KMT5A chr12 Not Cancer Driver No 1 hippie 41 225 22 22 0
KPNA1 KPNA1 P52294 Importin subunit alpha-5 chr3 Not Cancer Driver No 1 hippie 65 121 18 18 0
KPNA3 KPNA3 O00505 Importin subunit alpha-4 chr13 Not Cancer Driver No 1 hippie 65 108 11 11 0
KPNA5 KPNA5 O15131 Importin subunit alpha-6 chr6 Not Cancer Driver No 1 hippie 65 133 13 13 0
KPNA6 KPNA6 O60684 Importin subunit alpha-7 chr1 Not Cancer Driver No 1 hippie 70 97 17 17 0
L1TD1 L1TD1 Q5T7N2 LINE-1 type transposase domain-containing protein 1 chr1 Not Cancer Driver No 1 hippie 149 534 114 114 0
LAMP2_ENST00000200639 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX Not Cancer Driver No 1 hippie, biogrid 43 55 7 7 1
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 Not Cancer Driver No 1 hippie, biogrid 13 96 7 7 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 58 350 44 44 0
LCOR LCOR Q96JN0 Ligand-dependent corepressor chr10 Not Cancer Driver No 2 hippie, biogrid 54 388 46 46 0
LIN37 LIN37 Q96GY3 Protein lin-37 homolog chr19 Not Cancer Driver No 5 hippie, biogrid 34 239 34 34 0
LIN52 LIN52 Q52LA3 Protein lin-52 homolog chr14 Not Cancer Driver No 3 hippie, biogrid 13 42 3 3 0
LIN54 LIN54 Q6MZP7 Protein lin-54 homolog chr4 Not Cancer Driver No 2 hippie, biogrid 61 440 31 31 0
LIN9 LIN9 Q5TKA1 Protein lin-9 homolog chr1 Not Cancer Driver No 4 intact, hippie, biogrid 67 219 25 25 0
LMNA LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie 68 544 49 49 131
LOXL2 LOXL2 Q9Y4K0 Lysyl oxidase homolog 2 chr8 Not Cancer Driver No 1 hippie 134 39 4 4 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 519 90 17 17 23
MAP2K3 MAP2K3 P46734 Dual specificity mitogen-activated protein kinase kinase 3 chr17 Not Cancer Driver No 1 hippie 104 75 27 27 0
MBD2 MBD2 Q9UBB5 Methyl-CpG-binding domain protein 2 chr18 Not Cancer Driver No 3 hippie, biogrid 26 384 25 25 0
MBD3 MBD3 O95983 Methyl-CpG-binding domain protein 3 chr19 Not Cancer Driver No 4 hippie, biogrid 50 246 46 46 0
MBD3L1_ENST00000305625 MBD3L1 Q8WWY6 Methyl-CpG-binding domain protein 3-like 1 chr19 Not Cancer Driver No 4 intact, hippie, biogrid 41 68 18 18 0
MBD3L2 MBD3L2 Q8NHZ7 Methyl-CpG-binding domain protein 3-like 2 chr19 Not Cancer Driver No 2 hippie, biogrid 7 188 7 7 0
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 hippie, biogrid 104 275 38 38 1
MCM3_ENST00000229854 MCM3 P25205 DNA replication licensing factor MCM3 chr6 Not Cancer Driver No 1 hippie 92 310 47 47 0
MCM7 MCM7 P33993 DNA replication licensing factor MCM7 chr7 Not Cancer Driver No 1 hippie, biogrid 101 128 22 22 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 56 297 37 37 0
MECOM_ENST00000494292 MECOM Q03112 Histone-lysine N-methyltransferase MECOM chr3 Census, Compendium Yes 1 hippie 287 749 159 159 3
MED15 MED15 Q96RN5 Mediator of RNA polymerase II transcription subunit 15 chr22 Not Cancer Driver No 1 biogrid 95 558 72 72 0
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 Not Cancer Driver No 1 hippie 76 446 42 42 0
MIB1 MIB1 Q86YT6 E3 ubiquitin-protein ligase MIB1 chr18 Not Cancer Driver No 1 hippie 122 282 34 34 1
MIS12 MIS12 Q9H081 Protein MIS12 homolog chr17 Not Cancer Driver No 1 hippie, biogrid 14 15 2 2 0
MIS18A MIS18A Q9NYP9 Protein Mis18-alpha chr21 Not Cancer Driver No 1 hippie 20 15 1 1 0
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 Not Cancer Driver No 1 hippie 84 292 35 35 1
MTA1 MTA1 Q13330 Metastasis-associated protein MTA1 chr14 Not Cancer Driver No 6 intact, hippie, biogrid 92 327 42 42 0
MTA2 MTA2 O94776 Metastasis-associated protein MTA2 chr11 Not Cancer Driver No 5 hippie, biogrid 78 283 32 32 0
MTA3 MTA3 Q9BTC8 Metastasis-associated protein MTA3 chr2 Not Cancer Driver No 4 hippie, biogrid 48 169 18 18 0
MTF2 MTF2 Q9Y483 Metal-response element-binding transcription factor 2 chr1 Not Cancer Driver No 3 hippie, biogrid 70 225 28 28 0
MTPN MTPN P58546 Myotrophin chr7 Not Cancer Driver No 1 hippie 11 11 3 3 0
MYBL1 MYBL1 P10243 Myb-related protein A chr8 Not Cancer Driver No 1 hippie, biogrid 78 501 58 58 0
MYBL2 MYBL2 P10244 Myb-related protein B chr20 Not Cancer Driver No 3 hippie, biogrid 111 506 85 85 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NACC2_ENST00000371753 NACC2 Q96BF6 Nucleus accumbens-associated protein 2 chr9 Not Cancer Driver No 1 hippie 24 238 10 10 0
NAP1L1 NAP1L1 P55209 Nucleosome assembly protein 1-like 1 chr12 Not Cancer Driver No 1 hippie, biogrid 47 207 31 31 0
NASP NASP P49321 Nuclear autoantigenic sperm protein chr1 Not Cancer Driver No 3 intact, hippie, biogrid 95 615 81 81 0
NCOR1 NCOR1 O75376 Nuclear receptor corepressor 1 chr17 Census, Compendium Yes 1 hippie, biogrid 352 2347 340 340 0
NDN NDN Q99608 Necdin chr15 Not Cancer Driver No 1 hippie 123 117 42 42 0
NEDD8 NEDD8 Q15843 NEDD8 chr14 Not Cancer Driver No 1 hippie 10 36 5 5 0
NEK4 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 Not Cancer Driver No 1 hippie 78 492 49 49 0
NF2 NF2 P35240 Merlin chr22 Census, Compendium Yes 1 hippie 69 252 26 26 16
NFATC2 NFATC2 Q13469 Nuclear factor of activated T-cells, cytoplasmic 2 chr20 Census, Compendium Yes 1 hippie, biogrid 194 722 162 162 0
NFX1 NFX1 Q12986 Transcriptional repressor NF-X1 chr9 Not Cancer Driver No 1 hippie 121 491 46 46 0
NKX2-1_ENST00000518149 NKX2-1 P43699 Homeobox protein Nkx-2.1 chr14 Census, Compendium Yes 1 hippie 41 334 39 39 7
NKX3-2 NKX3-2 P78367 Homeobox protein Nkx-3.2 chr4 Not Cancer Driver No 1 hippie 36 212 27 27 0
NOL9 NOL9 Q5SY16 Polynucleotide 5'-hydroxyl-kinase NOL9 chr1 Not Cancer Driver No 1 hippie 73 102 8 8 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 Census, Compendium Yes 1 hippie 363 686 87 87 3
NPAT NPAT Q14207 Protein NPAT chr11 Not Cancer Driver No 1 hippie, biogrid 134 1149 113 113 0
NPC1 NPC1 O15118 NPC intracellular cholesterol transporter 1 chr18 Not Cancer Driver No 1 hippie 155 24 0 0 150
NPM1 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 hippie 29 249 22 22 0
NR2C1 NR2C1 P13056 Nuclear receptor subfamily 2 group C member 1 chr12 Not Cancer Driver No 1 hippie 65 156 13 13 0
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 hippie 62 186 24 24 0
NR2E3 NR2E3 Q9Y5X4 Photoreceptor-specific nuclear receptor chr15 Not Cancer Driver No 1 hippie 47 171 15 15 16
NR2F1_ENST00000327111 NR2F1 P10589 COUP transcription factor 1 chr5 Not Cancer Driver No 1 hippie 67 110 6 6 4
NSD2_ENST00000382892 NSD2 O96028 Histone-lysine N-methyltransferase NSD2 chr4 Census, Compendium Yes 1 hippie 191 552 76 76 0
NSL1 NSL1 Q96IY1 Kinetochore-associated protein NSL1 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 30 117 12 12 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 hippie 168 57 8 8 25
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 Not Cancer Driver No 2 hippie, biogrid 233 553 60 60 0
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX Not Cancer Driver No 1 hippie 156 89 16 16 2
P4HB P4HB P07237 Protein disulfide-isomerase chr17 Not Cancer Driver No 1 hippie 61 79 15 15 1
PAK4 PAK4 O96013 Serine/threonine-protein kinase PAK 4 chr19 Not Cancer Driver No 1 hippie 58 340 33 33 0
PAN2_ENST00000548043 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 Not Cancer Driver No 1 hippie 139 78 10 10 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 Not Cancer Driver No 1 hippie 11 30 0 0 5
PBK_ENST00000301905 PBK Q96KB5 Lymphokine-activated killer T-cell-originated protein kinase chr8 Not Cancer Driver No 1 hippie 23 92 6 6 0
PCLAF PCLAF Q15004 PCNA-associated factor chr15 Not Cancer Driver No 1 hippie 20 111 20 20 0
PDIA3 PDIA3 P30101 Protein disulfide-isomerase A3 chr15 Not Cancer Driver No 1 hippie 57 98 11 11 0
PGR PGR P06401 Progesterone receptor chr11 Not Cancer Driver No 1 intact, hippie 161 480 55 55 0
PHF1 PHF1 O43189 PHD finger protein 1 chr6 Not Cancer Driver No 2 hippie, biogrid 62 277 29 29 0
PHF12 PHF12 Q96QT6 PHD finger protein 12 chr17 Not Cancer Driver No 2 hippie, biogrid 107 619 68 68 0
PHF19_ENST00000373896 PHF19 Q5T6S3 PHD finger protein 19 chr9 Not Cancer Driver No 1 hippie 66 129 19 19 0
PHF6_ENST00000370803 PHF6 Q8IWS0 PHD finger protein 6 chrX Census, Compendium Yes 1 hippie 52 172 19 19 6
PIMREG PIMREG Q9BSJ6 Protein PIMREG chr17 Not Cancer Driver No 1 hippie 38 233 36 36 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 Not Cancer Driver No 1 hippie 57 99 13 13 23
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PLP1 PLP1 P60201 Myelin proteolipid protein chrX Not Cancer Driver No 1 hippie 49 5 1 1 72
POLD3 POLD3 Q15054 DNA polymerase delta subunit 3 chr11 Not Cancer Driver No 1 hippie 51 326 39 39 0
PPP1R8 PPP1R8 Q12972 Nuclear inhibitor of protein phosphatase 1 chr1 Not Cancer Driver No 1 hippie 24 251 19 19 0
PPT1 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 Not Cancer Driver No 1 hippie 37 0 0 0 23
PPTC7 PPTC7 Q8NI37 Protein phosphatase PTC7 homolog chr12 Not Cancer Driver No 1 hippie, biogrid 32 36 2 2 0
PRC1 PRC1 O43663 Protein regulator of cytokinesis 1 chr15 Not Cancer Driver No 1 hippie 63 235 26 26 0
PRDM16 PRDM16 Q9HAZ2 Histone-lysine N-methyltransferase PRDM16 chr1 Census Yes 1 hippie 254 830 152 152 1
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 182 537 141 141 0
PSMC4 PSMC4 P43686 26S proteasome regulatory subunit 6B chr19 Not Cancer Driver No 1 hippie, biogrid 51 21 3 3 0
PSMD13_ENST00000532097 PSMD13 Q9UNM6 26S proteasome non-ATPase regulatory subunit 13 chr11 Not Cancer Driver No 1 hippie, biogrid 30 13 3 3 0
PWWP2A PWWP2A Q96N64 PWWP domain-containing protein 2A chr5 Census Yes 3 hippie, biogrid 57 601 46 46 0
PWWP2B PWWP2B Q6NUJ5 PWWP domain-containing protein 2B chr10 Not Cancer Driver No 1 hippie, biogrid 60 451 51 51 0
RAD18 RAD18 Q9NS91 E3 ubiquitin-protein ligase RAD18 chr3 Not Cancer Driver No 1 hippie 59 328 43 43 0
RAN_ENST00000392369 RAN P62826 GTP-binding nuclear protein Ran chr12 Not Cancer Driver No 1 hippie 20 14 1 1 0
RASSF10 RASSF10 A6NK89 Ras association domain-containing protein 10 chr11 Not Cancer Driver No 1 hippie 11 372 8 8 0
RASSF9 RASSF9 O75901 Ras association domain-containing protein 9 chr12 Not Cancer Driver No 1 hippie 88 131 24 24 0
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 Census, Compendium Yes 1 hippie 140 282 32 32 22
RBBP4 RBBP4 Q09028 Histone-binding protein RBBP4 chr1 Not Cancer Driver No 1 hippie 53 169 23 23 0
RBBP7_ENST00000380087 RBBP7 Q16576 Histone-binding protein RBBP7 chrX Not Cancer Driver No 8 intact, hippie, biogrid 67 138 19 19 0
RBL1 RBL1 P28749 Retinoblastoma-like protein 1 chr20 Not Cancer Driver No 1 hippie, biogrid 140 335 41 41 0
RBL2 RBL2 Q08999 Retinoblastoma-like protein 2 chr16 Not Cancer Driver No 2 hippie, biogrid 116 504 56 56 0
RBM39 RBM39 Q14498 RNA-binding protein 39 chr20 Compendium Yes 1 hippie 81 228 39 39 0
RBP1_ENST00000619087 RBP1 P09455 Retinol-binding protein 1 chr3 Not Cancer Driver No 1 hippie 24 0 0 0 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 Census, Compendium Yes 1 hippie 138 608 71 71 1
REXO5 REXO5 Q96IC2 RNA exonuclease 5 chr16 Not Cancer Driver No 1 hippie 89 101 12 12 0
RNF138 RNF138 Q8WVD3 E3 ubiquitin-protein ligase RNF138 chr18 Not Cancer Driver No 1 hippie 44 34 6 6 0
RNF2 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 Not Cancer Driver No 1 hippie 40 203 22 22 0
RNF5 RNF5 Q99942 E3 ubiquitin-protein ligase RNF5 chr6 Not Cancer Driver No 1 hippie 17 69 3 3 0
RPLP0_ENST00000228306 RPLP0 P05388 60S acidic ribosomal protein P0 chr12 Not Cancer Driver No 1 hippie, biogrid 44 36 4 4 0
RPN1 RPN1 P04843 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 chr3 Census Yes 1 hippie 50 69 3 3 0
RPN2 RPN2 P04844 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 chr20 Not Cancer Driver No 1 hippie 53 26 4 4 0
RPS6KA3_ENST00000379565 RPS6KA3 P51812 Ribosomal protein S6 kinase alpha-3 chrX Compendium Yes 1 hippie 106 145 18 18 13
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 Not Cancer Driver No 1 hippie 176 241 21 21 0
RRP1B RRP1B Q14684 Ribosomal RNA processing protein 1 homolog B chr21 Not Cancer Driver No 1 hippie 74 513 48 48 0
RYBP RYBP Q8N488 RING1 and YY1-binding protein chr3 Not Cancer Driver No 1 hippie 37 214 37 37 0
SALL1 SALL1 Q9NSC2 Sal-like protein 1 chr16 Not Cancer Driver No 1 hippie, biogrid 454 949 334 334 0
SALL3 SALL3 Q9BXA9 Sal-like protein 3 chr18 Not Cancer Driver No 1 hippie, biogrid 250 1010 192 192 0
SALL4 SALL4 Q9UJQ4 Sal-like protein 4 chr20 Census, Compendium Yes 1 hippie 238 738 188 188 1
SAP130_ENST00000259235 SAP130 Q9H0E3 Histone deacetylase complex subunit SAP130 chr2 Not Cancer Driver No 1 hippie, biogrid 119 940 107 107 0
SAP30 SAP30 O75446 Histone deacetylase complex subunit SAP30 chr4 Not Cancer Driver No 3 hippie, biogrid 26 123 17 17 0
SAP30L SAP30L Q9HAJ7 Histone deacetylase complex subunit SAP30L chr5 Not Cancer Driver No 2 hippie, biogrid 18 111 14 14 0
SDAD1 SDAD1 Q9NVU7 Protein SDA1 homolog chr4 Not Cancer Driver No 1 hippie, biogrid 65 288 29 29 0
SENP7 SENP7 Q9BQF6 Sentrin-specific protease 7 chr3 Not Cancer Driver No 1 hippie 149 523 73 73 0
SETD1A SETD1A O15047 Histone-lysine N-methyltransferase SETD1A chr16 Not Cancer Driver No 1 hippie 223 1327 188 188 5
SH3GLB1_ENST00000370558 SH3GLB1 Q9Y371 Endophilin-B1 chr1 Not Cancer Driver No 1 hippie 41 82 10 10 0
SHPRH SHPRH Q149N8 E3 ubiquitin-protein ligase SHPRH chr6 Not Cancer Driver No 2 hippie, biogrid 227 359 51 51 0
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 Compendium Yes 3 hippie, biogrid 172 617 73 73 0
SIN3B SIN3B O75182 Paired amphipathic helix protein Sin3b chr19 Not Cancer Driver No 3 hippie, biogrid 130 316 32 32 0
SINHCAF_ENST00000454658 SINHCAF Q9NP50 SIN3-HDAC complex-associated factor chr12 Not Cancer Driver No 1 intact, hippie 24 108 10 10 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 Not Cancer Driver No 1 hippie 33 164 12 12 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 Not Cancer Driver No 1 hippie 48 163 15 15 0
SLFN11_ENST00000308377 SLFN11 Q7Z7L1 Schlafen family member 11 chr17 Not Cancer Driver No 1 hippie 177 34 8 8 0
SMARCA1_ENST00000371122 SMARCA1 P28370 Probable global transcription activator SNF2L1 chrX Compendium Yes 4 hippie, biogrid 143 309 41 41 0
SMARCA2 SMARCA2 P51531 Probable global transcription activator SNF2L2 chr9 Not Cancer Driver No 1 hippie 273 1009 160 160 42
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 Census, Compendium Yes 1 hippie 349 1072 195 195 5
SMARCA5 SMARCA5 O60264 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 chr4 Not Cancer Driver No 4 hippie, biogrid 116 363 48 48 0
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 Census, Compendium Yes 1 hippie 64 141 35 35 3
SMN1_ENST00000503079 SMN1 Q16637-2 Isoform SMN-delta5 of Survival motor neuron protein chr5 Not Cancer Driver No 1 hippie 2 181 2 2 0
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 Not Cancer Driver No 1 hippie 52 97 11 11 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 Not Cancer Driver No 1 hippie 16 93 9 9 79
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 hippie 39 312 39 39 0
SP1 SP1 P08047 Transcription factor Sp1 chr12 Not Cancer Driver No 1 hippie 96 599 71 71 0
SP3 SP3 Q02447 Transcription factor Sp3 chr2 Not Cancer Driver No 1 hippie 66 587 37 37 0
SPANXN4 SPANXN4 Q5MJ08 Sperm protein associated with the nucleus on the X chromosome N4 chrX Not Cancer Driver No 1 hippie, biogrid 15 99 15 15 0
SPEN SPEN Q96T58 Msx2-interacting protein chr1 Census, Compendium Yes 1 hippie 459 3061 393 393 0
SRRM2 SRRM2 Q9UQ35 Serine/arginine repetitive matrix protein 2 chr16 Not Cancer Driver No 1 hippie 433 2748 431 431 0
SRSF6 SRSF6 Q13247 Serine/arginine-rich splicing factor 6 chr20 Not Cancer Driver No 1 hippie, biogrid 69 259 49 49 0
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 Census, Compendium Yes 1 hippie 93 144 19 19 5
STIP1_ENST00000305218 STIP1 P31948 Stress-induced-phosphoprotein 1 chr11 Not Cancer Driver No 1 hippie 74 270 39 39 0
STK24 STK24 Q9Y6E0 Serine/threonine-protein kinase 24 chr13 Not Cancer Driver No 1 hippie 67 118 16 16 0
SUDS3 SUDS3 Q9H7L9 Sin3 histone deacetylase corepressor complex component SDS3 chr12 Not Cancer Driver No 2 hippie, biogrid 35 249 28 28 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SUV39H1_ENST00000376687 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX Not Cancer Driver No 1 hippie 59 15 1 1 0
SUZ12 SUZ12 Q15022 Polycomb protein SUZ12 chr17 Census, Compendium Yes 5 hippie, biogrid 83 483 46 46 3
TAF6_ENST00000344095 TAF6 P49848 Transcription initiation factor TFIID subunit 6 chr7 Not Cancer Driver No 1 hippie 79 288 32 32 2
TARDBP TARDBP Q13148 TAR DNA-binding protein 43 chr1 Not Cancer Driver No 1 hippie 51 202 15 15 27
TCF7L2_ENST00000355995 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 Census, Compendium Yes 1 hippie 122 516 93 93 0
TEX101_ENST00000598265 TEX101 Q9BY14 Testis-expressed protein 101 chr19 Not Cancer Driver No 1 hippie 45 2 0 0 0
TFDP1 TFDP1 Q14186 Transcription factor Dp-1 chr13 Not Cancer Driver No 1 hippie, biogrid 82 245 47 47 0
TFDP2 TFDP2 Q14188 Transcription factor Dp-2 chr3 Not Cancer Driver No 1 hippie, biogrid 62 248 33 33 0
TGIF2LX_ENST00000283891 TGIF2LX Q8IUE1 Homeobox protein TGIF2LX chrX Not Cancer Driver No 1 hippie, biogrid 117 215 101 101 0
TK1 TK1 P04183 Thymidine kinase, cytosolic chr17 Not Cancer Driver No 1 hippie 26 13 4 4 0
TNFRSF10D TNFRSF10D Q9UBN6 Tumor necrosis factor receptor superfamily member 10D chr8 Not Cancer Driver No 1 hippie 51 193 28 28 0
TNRC18 TNRC18 O15417 Trinucleotide repeat-containing gene 18 protein chr7 Not Cancer Driver No 1 hippie, biogrid 310 2580 271 271 0
TOPORS TOPORS Q9NS56 E3 ubiquitin-protein ligase Topors chr9 Not Cancer Driver No 1 hippie 149 795 105 105 0
TP53RK TP53RK Q96S44 EKC/KEOPS complex subunit TP53RK chr20 Not Cancer Driver No 1 hippie 20 51 2 2 3
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TRIM14 TRIM14 Q14142 Tripartite motif-containing protein 14 chr9 Not Cancer Driver No 1 hippie 36 93 7 7 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 Not Cancer Driver No 1 hippie 87 430 41 41 0
TRPS1_ENST00000220888 TRPS1 Q9UHF7 Zinc finger transcription factor Trps1 chr8 Not Cancer Driver No 1 hippie, biogrid 348 800 216 216 7
TSHZ1 TSHZ1 Q6ZSZ6 Teashirt homolog 1 chr18 Not Cancer Driver No 1 hippie, biogrid 161 799 129 129 0
TSHZ3 TSHZ3 Q63HK5 Teashirt homolog 3 chr19 Not Cancer Driver No 1 hippie, biogrid 354 869 281 281 0
TSSK3 TSSK3 Q96PN8 Testis-specific serine/threonine-protein kinase 3 chr1 Not Cancer Driver No 1 hippie 30 0 0 0 0
TUBA1C_ENST00000301072 TUBA1C Q9BQE3 Tubulin alpha-1C chain chr12 Not Cancer Driver No 1 hippie 39 50 5 5 0
TUBGCP3 TUBGCP3 Q96CW5 Gamma-tubulin complex component 3 chr13 Not Cancer Driver No 1 hippie 109 156 16 16 0
UBD UBD O15205 Ubiquitin D chr6 Not Cancer Driver No 1 hippie 31 8 1 1 0
UBE2A UBE2A P49459 Ubiquitin-conjugating enzyme E2 A chrX Compendium Yes 1 hippie 35 67 13 13 2
UBE2M UBE2M P61081 NEDD8-conjugating enzyme Ubc12 chr19 Not Cancer Driver No 1 hippie 30 32 6 6 0
UBN2 UBN2 Q6ZU65 Ubinuclein-2 chr7 Not Cancer Driver No 1 hippie, biogrid 157 1104 126 126 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
USF1 USF1 P22415 Upstream stimulatory factor 1 chr1 Not Cancer Driver No 1 hippie 52 271 44 44 0
USP11 USP11 P51784 Ubiquitin carboxyl-terminal hydrolase 11 chrX Not Cancer Driver No 1 hippie 140 210 28 28 0
USP43 USP43 Q70EL4 Ubiquitin carboxyl-terminal hydrolase 43 chr17 Not Cancer Driver No 1 hippie 134 562 56 56 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie, biogrid 88 186 16 16 16
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 Census, Compendium Yes 1 hippie 142 117 36 36 133
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 30 35 3 3 0
WDR76 WDR76 Q9H967 WD repeat-containing protein 76 chr15 Not Cancer Driver No 1 hippie 60 288 33 33 0
WDR77 WDR77 Q9BQA1 Methylosome protein 50 chr1 Not Cancer Driver No 1 hippie 30 41 2 2 0
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 Not Cancer Driver No 1 hippie, biogrid 66 140 12 12 0
YAF2_ENST00000534854 YAF2 Q8IY57 YY1-associated factor 2 chr12 Not Cancer Driver No 1 hippie 27 166 27 27 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 Not Cancer Driver No 1 hippie 51 489 49 49 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 hippie 32 41 3 3 0
ZBTB2 ZBTB2 Q8N680 Zinc finger and BTB domain-containing protein 2 chr6 Not Cancer Driver No 1 hippie, biogrid 75 216 30 30 0
ZBTB38_ENST00000441582 ZBTB38 Q8NAP3 Zinc finger and BTB domain-containing protein 38 chr3 Not Cancer Driver No 1 hippie 137 648 73 73 0
ZC3H18_ENST00000301011 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 1 hippie 139 929 134 134 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0
ZEB2_ENST00000558170 ZEB2 O60315 Zinc finger E-box-binding homeobox 2 chr2 Not Cancer Driver No 1 hippie 299 859 211 211 2
ZFPM1 ZFPM1 Q8IX07 Zinc finger protein ZFPM1 chr16 Not Cancer Driver No 2 hippie, biogrid 50 772 27 27 0
ZFPM2 ZFPM2 Q8WW38 Zinc finger protein ZFPM2 chr8 Not Cancer Driver No 1 hippie 374 659 233 233 8
ZGPAT ZGPAT Q8N5A5 Zinc finger CCCH-type with G patch domain-containing protein chr20 Not Cancer Driver No 1 hippie 75 346 49 49 0
ZMYND8_ENST00000311275 ZMYND8 Q9ULU4 Protein kinase C-binding protein 1 chr20 Not Cancer Driver No 1 hippie 176 830 124 124 0
ZNF219 ZNF219 Q9P2Y4 Zinc finger protein 219 chr14 Not Cancer Driver No 3 intact, hippie, biogrid 44 628 37 37 0
ZNF263 ZNF263 O14978 Zinc finger protein 263 chr16 Not Cancer Driver No 1 hippie 90 403 58 58 0
ZNF296 ZNF296 Q8WUU4 Zinc finger protein 296 chr19 Not Cancer Driver No 2 hippie, biogrid 47 342 36 36 0
ZNF423 ZNF423 Q2M1K9 Zinc finger protein 423 chr16 Not Cancer Driver No 1 hippie, biogrid 340 416 108 108 2
ZNF512B ZNF512B Q96KM6 Zinc finger protein 512B chr20 Not Cancer Driver No 3 hippie, biogrid 101 694 83 83 0
ZNF516 ZNF516 Q92618 Zinc finger protein 516 chr18 Not Cancer Driver No 1 hippie 177 861 131 131 0
ZNF521 ZNF521 Q96K83 Zinc finger protein 521 chr18 Census, Compendium Yes 1 hippie, biogrid 318 365 90 90 0
ZNF639_ENST00000621687 ZNF639 Q9UID6 Zinc finger protein 639 chr3 Not Cancer Driver No 1 hippie, biogrid 61 139 23 23 0
ZNF827 ZNF827 Q17R98 Zinc finger protein 827 chr4 Not Cancer Driver No 1 hippie 158 754 123 123 0