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PYHIN1 ,PYHIN1 ,Q6K0P9
  • Uniprot Accession= Q6K0P9
  • Ensembl Transcript= ENST00000368140.5
  • Uniprot Name= PYHIN1
  • Name= Pyrin and HIN domain-containing protein 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 101
  • Number of Interaction partner in biogrid: 128
  • Number of Interaction partner in hippie: 345
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCD3 ABCD3 P28288 ATP-binding cassette sub-family D member 3 chr1 Not Cancer Driver No 1 hippie 75 21 2 2 0
ABCF1 ABCF1 Q8NE71 ATP-binding cassette sub-family F member 1 chr6 Not Cancer Driver No 1 hippie 106 445 64 64 0
ACTR3 ACTR3 P61158 Actin-related protein 3 chr2 Not Cancer Driver No 1 hippie, biogrid 32 16 2 2 0
ADAMTS1 ADAMTS1 Q9UHI8 A disintegrin and metalloproteinase with thrombospondin motifs 1 chr21 Not Cancer Driver No 1 hippie 135 272 32 32 0
AGRN AGRN O00468 Agrin chr1 Not Cancer Driver No 1 intact, hippie, biogrid 188 490 40 40 5
AKAP8 AKAP8 O43823 A-kinase anchor protein 8 chr19 Not Cancer Driver No 1 hippie 88 566 78 78 0
AL662899.2_ENST00000375880 CSNK2B Q5SRQ3 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie 21 30 1 1 0
ANKRD17 ANKRD17 O75179 Ankyrin repeat domain-containing protein 17 chr4 Not Cancer Driver No 1 hippie 312 1790 221 221 9
APLP2 APLP2 Q06481 Amyloid beta precursor like protein 2 chr11 Not Cancer Driver No 1 hippie 96 393 48 48 0
ATIC ATIC P31939 Bifunctional purine biosynthesis protein ATIC chr2 Census Yes 1 intact, hippie, biogrid 74 25 1 1 1
ATP6V1B2 ATP6V1B2 P21281 V-type proton ATPase subunit B, brain isoform chr8 Not Cancer Driver No 1 intact, hippie, biogrid 63 49 4 4 1
ATRX ATRX P46100 Transcriptional regulator ATRX chrX Census, Compendium Yes 1 intact, hippie, biogrid 487 1672 301 301 33
BAZ1A_ENST00000382422 BAZ1A Q9NRL2 Bromodomain adjacent to zinc finger domain protein 1A chr14 Census Yes 1 intact, hippie, biogrid 156 752 65 65 0
BAZ1B_ENST00000404251 BAZ1B Q9UIG0 Tyrosine-protein kinase BAZ1B chr7 Not Cancer Driver No 1 intact, hippie, biogrid 153 840 87 87 0
BAZ2A BAZ2A Q9UIF9 Bromodomain adjacent to zinc finger domain protein 2A chr12 Not Cancer Driver No 1 intact, hippie, biogrid 186 1283 118 118 0
BOP1 BOP1 Q14137 Ribosome biogenesis protein BOP1 chr8 Not Cancer Driver No 1 hippie 20 304 19 19 0
BRIX1 BRIX1 Q8TDN6 Ribosome biogenesis protein BRX1 homolog chr5 Not Cancer Driver No 1 hippie 34 149 10 10 0
BSG BSG P35613 Basigin chr19 Not Cancer Driver No 1 hippie 43 123 17 17 0
BTBD2 BTBD2 Q9BX70 BTB/POZ domain-containing protein 2 chr19 Not Cancer Driver No 1 hippie 46 118 2 2 0
BUD13 BUD13 Q9BRD0 BUD13 homolog chr11 Not Cancer Driver No 1 hippie 77 594 73 73 0
BYSL BYSL Q13895 Bystin chr6 Not Cancer Driver No 1 hippie 38 176 14 14 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 Not Cancer Driver No 1 intact, hippie, biogrid 14 103 6 6 2
C5orf24_ENST00000435259 C5orf24 Q7Z6I8 UPF0461 protein C5orf24 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 22 182 22 22 0
C8orf33 C8orf33 Q9H7E9 UPF0488 protein C8orf33 chr8 Not Cancer Driver No 1 hippie 34 172 26 26 0
CABIN1 CABIN1 Q9Y6J0 Calcineurin-binding protein cabin-1 chr22 Not Cancer Driver No 1 intact, hippie, biogrid 225 1008 95 95 0
CACYBP CACYBP Q9HB71 Calcyclin-binding protein chr1 Not Cancer Driver No 1 hippie, biogrid 27 92 10 10 0
CALHM4_ENST00000368596 CALHM4 Q5JW98 Calcium homeostasis modulator protein 4 chr6 Not Cancer Driver No 2 intact, hippie 23 19 3 3 0
CALML3 CALML3 P27482 Calmodulin-like protein 3 chr10 Not Cancer Driver No 2 hippie, biogrid 34 105 28 28 0
CBX5 CBX5 P45973 Chromobox protein homolog 5 chr12 Not Cancer Driver No 1 intact, hippie, biogrid 21 116 12 12 0
CCAR2 CCAR2 Q8N163 Cell cycle and apoptosis regulator protein 2 chr8 Not Cancer Driver No 1 intact, hippie, biogrid 102 528 62 62 0
CCDC86 CCDC86 Q9H6F5 Coiled-coil domain-containing protein 86 chr11 Not Cancer Driver No 1 hippie 36 360 36 36 0
CDC40 CDC40 O60508 Pre-mRNA-processing factor 17 chr6 Not Cancer Driver No 1 hippie 79 214 27 27 1
CDK11B CDK11B P21127 Cyclin-dependent kinase 11B chr1 Not Cancer Driver No 1 hippie 74 501 35 35 0
CENPB CENPB P07199 Major centromere autoantigen B chr20 Not Cancer Driver No 1 hippie 64 374 39 39 0
CENPV CENPV Q7Z7K6 Centromere protein V chr17 Not Cancer Driver No 1 hippie 16 154 2 2 0
CHD1 CHD1 O14646 Chromodomain-helicase-DNA-binding protein 1 chr5 Not Cancer Driver No 1 hippie 172 975 109 109 4
CHD4 CHD4 Q14839 Chromodomain-helicase-DNA-binding protein 4 chr12 Census, Compendium Yes 1 intact, hippie, biogrid 419 974 177 177 6
CHERP CHERP Q8IWX8 Calcium homeostasis endoplasmic reticulum protein chr19 Not Cancer Driver No 1 hippie 109 707 79 79 0
CHMP1A CHMP1A Q9HD42 Charged multivesicular body protein 1a chr16 Not Cancer Driver No 1 hippie 18 110 6 6 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
CKAP5 CKAP5 Q14008 Cytoskeleton-associated protein 5 chr11 Not Cancer Driver No 1 hippie 198 634 64 64 0
COL18A1 COL18A1 P39060 Collagen alpha-1(XVIII) chain chr21 Not Cancer Driver No 1 intact, hippie, biogrid 179 1284 142 142 0
COPA_ENST00000241704 COPA P53621 Coatomer subunit alpha chr1 Not Cancer Driver No 1 intact, hippie, biogrid 163 157 18 18 4
CPSF2 CPSF2 Q9P2I0 Cleavage and polyadenylation specificity factor subunit 2 chr14 Not Cancer Driver No 1 hippie 76 231 22 22 0
CPSF6_ENST00000435070 CPSF6 Q16630 Cleavage and polyadenylation specificity factor subunit 6 chr12 Not Cancer Driver No 1 hippie 85 484 75 75 0
CRYBG1 CRYBG1 Q9Y4K1 Beta/gamma crystallin domain-containing protein 1 chr6 Not Cancer Driver No 2 intact, hippie 211 1006 124 124 0
CSNK2A2 CSNK2A2 P19784 Casein kinase II subunit alpha' chr16 Not Cancer Driver No 1 hippie 43 13 1 1 0
CSNK2B_ENST00000375866 CSNK2B P67870 Casein kinase II subunit beta chr6 Not Cancer Driver No 1 hippie 20 19 0 0 4
CTCF CTCF P49711 Transcriptional repressor CTCF chr16 Census, Compendium Yes 1 hippie, biogrid 151 481 83 83 1
CTR9 CTR9 Q6PD62 RNA polymerase-associated protein CTR9 homolog chr11 Not Cancer Driver No 1 hippie 164 385 48 48 0
CUL3 CUL3 Q13618 Cullin-3 chr2 Census, Compendium Yes 1 hippie 123 167 23 23 3
CUL4A CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 hippie 64 102 2 2 0
CWC15 CWC15 Q9P013 Spliceosome-associated protein CWC15 homolog chr11 Not Cancer Driver No 1 hippie 23 204 21 21 0
DAP3_ENST00000343043 DAP3 P51398 28S ribosomal protein S29, mitochondrial chr1 Not Cancer Driver No 1 hippie 58 82 14 14 0
DAXX_ENST00000266000 DAXX Q9UER7 Death domain-associated protein 6 chr6 Census, Compendium Yes 1 intact, hippie, biogrid 106 549 81 81 0
DCAF1 DCAF1 Q9Y4B6 DDB1- and CUL4-associated factor 1 chr3 Not Cancer Driver No 3 intact, hippie 128 495 44 44 0
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 Not Cancer Driver No 1 intact, biogrid 126 50 8 8 4
DDX50 DDX50 Q9BQ39 ATP-dependent RNA helicase DDX50 chr10 Not Cancer Driver No 1 hippie 86 274 30 30 0
DHRS2_ENST00000250383 DHRS2 Q13268 Dehydrogenase/reductase SDR family member 2, mitochondrial chr14 Not Cancer Driver No 1 hippie 47 0 0 0 0
DHX16 DHX16 O60231 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 chr6 Not Cancer Driver No 1 hippie 128 391 59 59 1
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 Not Cancer Driver No 1 hippie 159 222 39 39 0
DICER1 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 Census, Compendium Yes 1 hippie 264 362 45 45 4
DNAJC7 DNAJC7 Q99615 DnaJ homolog subfamily C member 7 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 41 102 9 9 0
DNAJC9 DNAJC9 Q8WXX5 DnaJ homolog subfamily C member 9 chr10 Not Cancer Driver No 1 intact, hippie, biogrid 28 126 15 15 0
DNMT1_ENST00000340748 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 Not Cancer Driver No 1 hippie, biogrid 203 702 78 78 4
DSG4_ENST00000308128 DSG4 Q86SJ6 Desmoglein-4 chr18 Not Cancer Driver No 3 intact, hippie, biogrid 275 186 44 44 0
DUSP12 DUSP12 Q9UNI6 Dual specificity protein phosphatase 12 chr1 Not Cancer Driver No 1 hippie 33 30 1 1 0
EGFLAM EGFLAM Q63HQ2 Pikachurin chr5 Not Cancer Driver No 1 hippie 283 193 83 83 0
EIF3D EIF3D O15371 Eukaryotic translation initiation factor 3 subunit D chr22 Not Cancer Driver No 1 hippie 63 200 26 26 0
EIF3I EIF3I Q13347 Eukaryotic translation initiation factor 3 subunit I chr1 Not Cancer Driver No 1 hippie 47 46 6 6 0
EIF4E_ENST00000450253 EIF4E P06730 Eukaryotic translation initiation factor 4E chr4 Not Cancer Driver No 1 hippie 26 54 6 6 0
EIF5B EIF5B O60841 Eukaryotic translation initiation factor 5B chr2 Not Cancer Driver No 1 hippie 122 718 71 71 0
EXOSC10 EXOSC10 Q01780 Exosome component 10 chr1 Not Cancer Driver No 1 hippie 87 375 35 35 0
EXOSC4 EXOSC4 Q9NPD3 Exosome complex component RRP41 chr8 Not Cancer Driver No 1 hippie 34 23 0 0 0
EXOSC9_ENST00000243498 EXOSC9 Q06265 Exosome complex component RRP45 chr4 Not Cancer Driver No 1 hippie 58 154 18 18 1
FAM120A FAM120A Q9NZB2 Constitutive coactivator of PPAR-gamma-like protein 1 chr9 Not Cancer Driver No 1 hippie 123 516 58 58 0
FBXW11 FBXW11 Q9UKB1 F-box/WD repeat-containing protein 11 chr5 Not Cancer Driver No 1 hippie 75 20 3 3 7
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 Not Cancer Driver No 1 hippie, biogrid 33 411 24 24 32
FUBP3 FUBP3 Q96I24 Far upstream element-binding protein 3 chr9 Not Cancer Driver No 1 hippie 68 353 51 51 0
G3BP2_ENST00000395719 G3BP2 Q9UN86 Ras GTPase-activating protein-binding protein 2 chr4 Not Cancer Driver No 1 hippie 64 384 53 53 0
GAR1 GAR1 Q9NY12 H/ACA ribonucleoprotein complex subunit 1 chr4 Not Cancer Driver No 1 hippie 23 141 14 14 0
GATAD2B_ENST00000634544 GATAD2B Q8WXI9 Transcriptional repressor p66-beta chr1 Not Cancer Driver No 1 hippie, biogrid 76 510 67 67 0
GIGYF2_ENST00000409547 GIGYF2 Q6Y7W6 GRB10-interacting GYF protein 2 chr2 Not Cancer Driver No 1 hippie 176 1096 158 158 6
GLG1_ENST00000422840 GLG1 Q92896 Golgi apparatus protein 1 chr16 Not Cancer Driver No 1 hippie 134 103 7 7 0
GNL3L_ENST00000360845 GNL3L Q9NVN8 Guanine nucleotide-binding protein-like 3-like protein chrX Not Cancer Driver No 1 hippie 120 242 43 43 0
GPC1 GPC1 P35052 Glypican-1 chr2 Not Cancer Driver No 1 hippie 58 166 14 14 0
GPC3_ENST00000370818 GPC3 P51654 Glypican-3 chrX Census Yes 1 hippie 89 86 11 11 1
GPC4 GPC4 O75487 Glypican-4 chrX Not Cancer Driver No 1 intact, hippie, biogrid 88 122 16 16 0
GPC6 GPC6 Q9Y625 Glypican-6 chr13 Not Cancer Driver No 1 hippie 133 140 36 36 0
GTF3C3 GTF3C3 Q9Y5Q9 General transcription factor 3C polypeptide 3 chr2 Not Cancer Driver No 1 hippie 109 195 22 22 0
GTF3C4 GTF3C4 Q9UKN8 General transcription factor 3C polypeptide 4 chr9 Not Cancer Driver No 1 hippie 76 164 13 13 0
GTPBP1 GTPBP1 O00178 GTP-binding protein 1 chr22 Not Cancer Driver No 1 hippie 75 263 26 26 0
GTPBP4 GTPBP4 Q9BZE4 GTP-binding protein 4 chr10 Not Cancer Driver No 1 intact, hippie, biogrid 79 232 34 34 0
H1FX H1-10 Q92522 Histone H1.10 chr3 Not Cancer Driver No 1 intact 12 198 12 12 0
H2AFY2 MACROH2A2 Q9P0M6 Core histone macro-H2A.2 chr10 Not Cancer Driver No 1 intact 59 171 32 32 0
HAT1 HAT1 O14929 Histone acetyltransferase type B catalytic subunit chr2 Not Cancer Driver No 1 hippie, biogrid 51 14 2 2 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 Not Cancer Driver No 1 hippie 46 145 14 14 0
HDGFL2 HDGFL2 Q7Z4V5 Hepatoma-derived growth factor-related protein 2 chr19 Not Cancer Driver No 1 hippie 59 622 57 57 0
HEPHL1 HEPHL1 Q6MZM0 Ferroxidase HEPHL1 chr11 Not Cancer Driver No 3 intact, hippie, biogrid 253 110 26 26 2
HERC5 HERC5 Q9UII4 E3 ISG15--protein ligase HERC5 chr4 Not Cancer Driver No 1 hippie 124 118 12 12 0
HIRA HIRA P54198 Protein HIRA chr22 Not Cancer Driver No 1 intact, hippie, biogrid 138 288 37 37 0
HIST1H1C H1-2 P16403 Histone H1.2 chr6 Not Cancer Driver No 1 intact 79 211 78 78 0
HIST1H1E H1-4 P10412 Histone H1.4 chr6 Not Cancer Driver No 1 intact 66 213 63 63 0
HIST1H4A H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 15 31 5 5 0
HIST1H4B H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 29 31 6 6 0
HIST1H4C H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 29 31 7 7 0
HIST1H4D H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 32 31 8 8 0
HIST1H4E H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 45 31 14 14 0
HIST1H4F H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 30 31 7 7 0
HIST1H4H H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 22 31 9 9 0
HIST1H4I H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 33 31 10 10 0
HIST1H4J H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 26 31 9 9 0
HIST1H4K H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 44 31 13 13 0
HIST1H4L H4-16 P62805 Histone H4 chr6 Not Cancer Driver No 1 intact 25 31 14 14 0
HIST4H4 H4-16 P62805 Histone H4 chr12 Not Cancer Driver No 1 intact 21 31 7 7 0
HMBOX1_ENST00000397358 HMBOX1 Q6NT76 Homeobox-containing protein 1 chr8 Not Cancer Driver No 1 intact, hippie, biogrid 55 319 41 41 0
HNRNPL HNRNPL P14866 Heterogeneous nuclear ribonucleoprotein L chr19 Not Cancer Driver No 1 hippie 89 283 29 29 0
HNRNPR_ENST00000374612 HNRNPR O43390 Heterogeneous nuclear ribonucleoprotein R chr1 Not Cancer Driver No 1 hippie 67 304 25 25 0
HOXA13 HOXA13 P31271 Homeobox protein Hox-A13 chr7 Census Yes 1 intact, hippie, biogrid 37 171 22 22 4
HP1BP3 HP1BP3 Q5SSJ5 Heterochromatin protein 1-binding protein 3 chr1 Not Cancer Driver No 2 hippie, biogrid 58 404 45 45 0
HSPG2 HSPG2 P98160 Basement membrane-specific heparan sulfate proteoglycan core protein chr1 Compendium Yes 1 hippie, biogrid 506 1709 194 194 1
HTATSF1_ENST00000218364 HTATSF1 O43719 HIV Tat-specific factor 1 chrX Not Cancer Driver No 1 intact, hippie, biogrid 131 573 100 100 0
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX Not Cancer Driver No 1 hippie, biogrid 669 2091 329 329 21
IKZF5 IKZF5 Q9H5V7 Zinc finger protein Pegasus chr10 Not Cancer Driver No 1 hippie, biogrid 46 282 36 36 0
KEAP1_ENST00000393623 KEAP1 Q14145 Kelch-like ECH-associated protein 1 chr19 Census, Compendium Yes 1 hippie 237 57 12 12 0
KHDRBS1 KHDRBS1 Q07666 KH domain-containing, RNA-binding, signal transduction-associated protein 1 chr1 Not Cancer Driver No 1 hippie 53 362 43 43 0
KIF5B KIF5B P33176 Kinesin-1 heavy chain chr10 Census, Compendium Yes 1 hippie, biogrid 122 586 67 67 0
KPNA3 KPNA3 O00505 Importin subunit alpha-4 chr13 Not Cancer Driver No 1 hippie 65 108 11 11 0
KPNA4 KPNA4 O00629 Importin subunit alpha-3 chr3 Not Cancer Driver No 1 hippie 59 112 12 12 0
KRI1 KRI1 Q8N9T8 Protein KRI1 homolog chr19 Not Cancer Driver No 1 hippie 91 607 84 84 0
LAMA1 LAMA1 P25391 Laminin subunit alpha-1 chr18 Not Cancer Driver No 1 hippie 600 329 71 71 0
LAMA4 LAMA4 Q16363 Laminin subunit alpha-4 chr6 Not Cancer Driver No 1 hippie 323 486 87 87 1
LAMA5 LAMA5 O15230 Laminin subunit alpha-5 chr20 Not Cancer Driver No 1 hippie 431 701 90 90 0
LAMB1 LAMB1 P07942 Laminin subunit beta-1 chr7 Not Cancer Driver No 1 intact, hippie, biogrid 240 418 50 50 0
LAMC1 LAMC1 P11047 Laminin subunit gamma-1 chr1 Not Cancer Driver No 1 hippie, biogrid 232 562 94 94 0
LARP1 LARP1 Q6PKG0-3 Isoform 2 of La-related protein 1 chr5 Not Cancer Driver No 1 hippie 136 726 100 100 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 58 350 44 44 0
LAS1L LAS1L Q9Y4W2 Ribosomal biogenesis protein LAS1L chrX Not Cancer Driver No 1 intact, hippie, biogrid 100 279 49 49 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 Not Cancer Driver No 3 intact, hippie, biogrid 15 133 6 6 0
LIG3 LIG3 P49916 DNA ligase 3 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 125 280 36 36 0
LLPH_ENST00000446587 LLPH Q9BRT6 Protein LLP homolog chr12 Not Cancer Driver No 1 hippie 15 113 14 14 0
LRRC15_ENST00000347624 LRRC15 Q8TF66 Leucine-rich repeat-containing protein 15 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 124 37 11 11 0
LSG1 LSG1 Q9H089 Large subunit GTPase 1 homolog chr3 Not Cancer Driver No 1 hippie 73 369 42 42 0
LSM12 LSM12 Q3MHD2 Protein LSM12 homolog chr17 Not Cancer Driver No 1 hippie 13 66 7 7 0
LTV1 LTV1 Q96GA3 Protein LTV1 homolog chr6 Not Cancer Driver No 1 hippie 45 388 30 30 0
LUC7L3_ENST00000240304 LUC7L3 O95232 Luc7-like protein 3 chr17 Not Cancer Driver No 1 hippie 59 323 47 47 0
LYAR_ENST00000452476 LYAR Q9NX58 Cell growth-regulating nucleolar protein chr4 Not Cancer Driver No 1 hippie 50 249 31 31 0
LYG2 LYG2 Q86SG7 Lysozyme g-like protein 2 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 38 1 1 1 0
MAGOHB MAGOHB Q96A72 Protein mago nashi homolog 2 chr12 Not Cancer Driver No 1 hippie 15 6 1 1 0
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 Not Cancer Driver No 1 intact, hippie, biogrid 332 1947 278 278 0
MBD1_ENST00000591416 MBD1 Q9UIS9 Methyl-CpG-binding domain protein 1 chr18 Not Cancer Driver No 1 hippie, biogrid 115 322 49 49 0
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 104 275 38 38 1
MCM4 MCM4 P33991 DNA replication licensing factor MCM4 chr8 Not Cancer Driver No 1 intact, hippie, biogrid 121 215 35 35 0
MDC1 MDC1 Q14676 Mediator of DNA damage checkpoint protein 1 chr6 Not Cancer Driver No 1 hippie, biogrid 249 1829 223 223 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 2 hippie, biogrid 56 297 37 37 0
MDN1 MDN1 Q9NU22 Midasin chr6 Not Cancer Driver No 1 hippie 678 983 107 107 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX Not Cancer Driver No 1 intact, hippie, biogrid 75 483 74 74 46
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 Not Cancer Driver No 1 hippie 76 446 42 42 0
MGA MGA Q8IWI9 MAX gene-associated protein chr15 Compendium Yes 1 intact, hippie, biogrid 341 2317 259 259 0
MKI67 MKI67 P46013 Proliferation marker protein Ki-67 chr10 Not Cancer Driver No 1 intact, hippie, biogrid 540 3169 529 529 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
MPHOSPH10 MPHOSPH10 O00566 U3 small nucleolar ribonucleoprotein protein MPP10 chr2 Not Cancer Driver No 1 hippie 105 518 82 82 0
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 Not Cancer Driver No 1 hippie 84 292 35 35 1
MRPL47 MRPL47 Q9HD33 39S ribosomal protein L47, mitochondrial chr3 Not Cancer Driver No 1 hippie 44 34 7 7 0
MRPS18B MRPS18B Q9Y676 28S ribosomal protein S18b, mitochondrial chr6 Not Cancer Driver No 1 hippie 31 112 12 12 0
MRPS22 MRPS22 P82650 28S ribosomal protein S22, mitochondrial chr3 Not Cancer Driver No 1 hippie 51 65 8 8 1
MRPS34_ENST00000397375 MRPS34 P82930 28S ribosomal protein S34, mitochondrial chr16 Not Cancer Driver No 1 hippie 13 56 2 2 1
MRPS7 MRPS7 Q9Y2R9 28S ribosomal protein S7, mitochondrial chr17 Not Cancer Driver No 1 hippie 31 26 0 0 1
MRTO4 MRTO4 Q9UKD2 mRNA turnover protein 4 homolog chr1 Not Cancer Driver No 1 hippie 23 73 5 5 0
MTA1 MTA1 Q13330 Metastasis-associated protein MTA1 chr14 Not Cancer Driver No 1 hippie 92 327 42 42 0
MTA2 MTA2 O94776 Metastasis-associated protein MTA2 chr11 Not Cancer Driver No 1 hippie 78 283 32 32 0
MYEF2 MYEF2 Q9P2K5 Myelin expression factor 2 chr15 Not Cancer Driver No 1 hippie 85 370 45 45 0
NAP1L1 NAP1L1 P55209 Nucleosome assembly protein 1-like 1 chr12 Not Cancer Driver No 1 hippie 47 207 31 31 0
NBN NBN O60934 Nibrin chr8 Census Yes 1 hippie, biogrid 90 417 54 54 1
NCBP1 NCBP1 Q09161 Nuclear cap-binding protein subunit 1 chr9 Not Cancer Driver No 1 hippie 88 89 8 8 0
NCOA5 NCOA5 Q9HCD5 Nuclear receptor coactivator 5 chr20 Not Cancer Driver No 1 intact, hippie, biogrid 84 478 70 70 0
NEU2 NEU2 Q9Y3R4 Sialidase-2 chr2 Not Cancer Driver No 2 intact, hippie, biogrid 88 144 32 32 0
NID1 NID1 P14543 Nidogen-1 chr1 Not Cancer Driver No 1 hippie 246 340 72 72 0
NIP7 NIP7 Q9Y221 60S ribosome subunit biogenesis protein NIP7 homolog chr16 Not Cancer Driver No 1 hippie 16 1 0 0 0
NKRF_ENST00000304449 NKRF O15226 NF-kappa-B-repressing factor chrX Not Cancer Driver No 1 hippie 100 366 49 49 0
NKX2-4 NKX2-4 Q9H2Z4 Homeobox protein Nkx-2.4 chr20 Not Cancer Driver No 1 hippie, biogrid 22 242 21 21 0
NMNAT1 NMNAT1 Q9HAN9 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 chr1 Not Cancer Driver No 1 hippie 39 49 7 7 28
NOB1 NOB1 Q9ULX3 RNA-binding protein NOB1 chr16 Not Cancer Driver No 1 hippie 38 185 15 15 0
NOC2L NOC2L Q9Y3T9 Nucleolar complex protein 2 homolog chr1 Not Cancer Driver No 1 hippie 77 281 31 31 0
NOL9 NOL9 Q5SY16 Polynucleotide 5'-hydroxyl-kinase NOL9 chr1 Not Cancer Driver No 1 hippie 73 102 8 8 0
NOP16_ENST00000614830 NOP16 Q9Y3C1 Nucleolar protein 16 chr5 Not Cancer Driver No 1 hippie 19 118 12 12 0
NOP53 NOP53 Q9NZM5 Ribosome biogenesis protein NOP53 chr19 Not Cancer Driver No 1 hippie 59 391 41 41 0
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 62 186 24 24 0
NR2F2 NR2F2 P24468 COUP transcription factor 2 chr15 Not Cancer Driver No 1 intact, hippie, biogrid 66 101 1 1 5
NRP1 NRP1 O14786 Neuropilin-1 chr10 Compendium Yes 1 hippie 146 211 31 31 0
NRXN3_ENST00000557594 NRXN3 Q9HDB5 Neurexin-3-beta chr14 Not Cancer Driver No 1 hippie 110 382 61 61 0
NSUN2 NSUN2 Q08J23 RNA cytosine C(5)-methyltransferase NSUN2 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 112 221 21 21 1
NUMA1 NUMA1 Q14980 Nuclear mitotic apparatus protein 1 chr11 Census, Compendium Yes 1 hippie, biogrid 234 1864 203 203 0
NVL NVL O15381 Nuclear valosin-containing protein-like chr1 Not Cancer Driver No 1 hippie 90 267 31 31 0
PADI3 PADI3 Q9ULW8 Protein-arginine deiminase type-3 chr1 Not Cancer Driver No 3 hippie, biogrid 139 25 8 8 3
PAF1 PAF1 Q8N7H5 RNA polymerase II-associated factor 1 homolog chr19 Not Cancer Driver No 1 hippie 77 378 56 56 0
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 119 320 34 34 0
PARP2 PARP2 Q9UGN5 Poly [ADP-ribose] polymerase 2 chr14 Not Cancer Driver No 1 intact, hippie, biogrid 74 172 23 23 0
PELP1_ENST00000574876 PELP1 Q8IZL8 Proline-, glutamic acid- and leucine-rich protein 1 chr17 Not Cancer Driver No 1 hippie, biogrid 134 610 82 82 0
PES1 PES1 O00541 Pescadillo homolog chr22 Not Cancer Driver No 1 hippie 78 248 33 33 0
PGK1 PGK1 P00558 Phosphoglycerate kinase 1 chrX Not Cancer Driver No 1 hippie, biogrid 61 40 5 5 9
PHF14 PHF14 O94880 PHD finger protein 14 chr7 Not Cancer Driver No 1 hippie, biogrid 102 565 56 56 0
PHF3 PHF3 Q92576 PHD finger protein 3 chr6 Not Cancer Driver No 1 hippie 260 1718 217 217 0
PHF5A PHF5A Q7RTV0 PHD finger-like domain-containing protein 5A chr22 Not Cancer Driver No 1 hippie 20 0 0 0 0
PHIP PHIP Q8WWQ0 PH-interacting protein chr6 Not Cancer Driver No 1 hippie, biogrid 239 835 110 110 0
PLCD1_ENST00000334661 PLCD1 P51178 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 94 111 13 13 2
PLS3_ENST00000539310 PLS3 P13797 Plastin-3 chrX Not Cancer Driver No 1 hippie, biogrid 75 75 5 5 0
PML PML P29590 Protein PML chr15 Census, Compendium Yes 1 intact, hippie, biogrid 112 312 34 34 0
POLR2A POLR2A P24928-2 Isoform 2 of DNA-directed RNA polymerase II subunit RPB1 chr17 Census Yes 1 hippie 56 230 20 20 0
POLR2E POLR2E P19388 DNA-directed RNA polymerases I, II, and III subunit RPABC1 chr19 Not Cancer Driver No 1 hippie 31 36 3 3 0
POLR2H_ENST00000456318 POLR2H P52434 DNA-directed RNA polymerases I, II, and III subunit RPABC3 chr3 Not Cancer Driver No 1 hippie 16 14 1 1 0
PPHLN1_ENST00000610488 PPHLN1 Q8NEY8 Periphilin-1 chr12 Not Cancer Driver No 1 hippie 64 447 62 62 0
PPIL1 PPIL1 Q9Y3C6 Peptidyl-prolyl cis-trans isomerase-like 1 chr6 Not Cancer Driver No 1 hippie 25 42 11 11 3
PPM1G PPM1G O15355 Protein phosphatase 1G chr2 Not Cancer Driver No 1 hippie, biogrid 51 359 39 39 0
PRPF3 PRPF3 O43395 U4/U6 small nuclear ribonucleoprotein Prp3 chr1 Not Cancer Driver No 1 hippie 97 523 75 75 2
PRPF38A PRPF38A Q8NAV1 Pre-mRNA-splicing factor 38A chr1 Not Cancer Driver No 1 hippie 39 142 22 22 0
PRPF4 PRPF4 O43172 U4/U6 small nuclear ribonucleoprotein Prp4 chr9 Not Cancer Driver No 1 hippie 61 152 15 15 2
PRRC2B PRRC2B Q5JSZ5 Protein PRRC2B chr9 Not Cancer Driver No 1 hippie 279 2199 278 278 0
PSMB7 PSMB7 Q99436 Proteasome subunit beta type-7 chr9 Not Cancer Driver No 1 hippie 25 26 3 3 0
PUM1_ENST00000257075 PUM1 Q14671 Pumilio homolog 1 chr1 Not Cancer Driver No 1 hippie 150 640 77 77 3
PYHIN1 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 Not Cancer Driver No 2 hippie, biogrid 174 291 99 99 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 Not Cancer Driver No 1 hippie 34 13 0 0 0
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 157 730 84 84 0
RAI1 RAI1 Q7Z5J4 Retinoic acid-induced protein 1 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 208 1690 188 188 0
RANBP1_ENST00000331821 RANBP1 P43487 Ran-specific GTPase-activating protein chr22 Not Cancer Driver No 1 hippie, biogrid 19 137 16 16 0
RBBP5 RBBP5 Q15291 Retinoblastoma-binding protein 5 chr1 Not Cancer Driver No 1 hippie 57 218 19 19 0
RBBP7_ENST00000380087 RBBP7 Q16576 Histone-binding protein RBBP7 chrX Not Cancer Driver No 1 intact, hippie, biogrid 67 138 19 19 0
RBX1 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 Not Cancer Driver No 1 hippie 10 18 1 1 0
RCN2_ENST00000394885 RCN2 Q14257 Reticulocalbin-2 chr15 Not Cancer Driver No 1 intact, hippie, biogrid 35 125 11 11 0
RFC2 RFC2 P35250 Replication factor C subunit 2 chr7 Not Cancer Driver No 1 hippie 45 39 6 6 0
RFX1 RFX1 P22670 MHC class II regulatory factor RFX1 chr19 Not Cancer Driver No 1 hippie, biogrid 114 536 66 66 0
RIOK2 RIOK2 Q9BVS4 Serine/threonine-protein kinase RIO2 chr5 Not Cancer Driver No 1 hippie 68 253 33 33 0
RNH1_ENST00000397604 RNH1 P13489 Ribonuclease inhibitor chr11 Not Cancer Driver No 1 intact, hippie, biogrid 40 0 0 0 0
RPL10_ENST00000369817 RPL10 P27635 60S ribosomal protein L10 chrX Census, Compendium Yes 1 hippie 46 9 3 3 4
RPL19 RPL19 P84098 60S ribosomal protein L19 chr17 Not Cancer Driver No 1 hippie 30 121 21 21 0
RPL23A RPL23A P62750 60S ribosomal protein L23a chr17 Not Cancer Driver No 1 hippie 21 70 13 13 0
RPL29_ENST00000475248 RPL29 P47914 60S ribosomal protein L29 chr3 Not Cancer Driver No 1 hippie 9 159 9 9 0
RPL34_ENST00000502534 RPL34 P49207 60S ribosomal protein L34 chr4 Not Cancer Driver No 1 hippie 11 31 1 1 0
RPL36AL RPL36AL Q969Q0 60S ribosomal protein L36a-like chr14 Not Cancer Driver No 1 hippie 9 64 7 7 0
RPL36A_ENST00000553110 RPL36A P83881 60S ribosomal protein L36a chrX Not Cancer Driver No 1 hippie 17 64 10 10 0
RPL36_ENST00000347512 RPL36 Q9Y3U8 60S ribosomal protein L36 chr19 Not Cancer Driver No 1 hippie 7 66 4 4 0
RPL4 RPL4 P36578 60S ribosomal protein L4 chr15 Not Cancer Driver No 1 hippie 49 222 31 31 0
RPL6 RPL6 Q02878 60S ribosomal protein L6 chr12 Not Cancer Driver No 1 hippie 41 159 24 24 0
RPL7 RPL7 P18124 60S ribosomal protein L7 chr8 Not Cancer Driver No 1 hippie 24 40 4 4 0
RPL7A RPL7A P62424 60S ribosomal protein L7a chr9 Not Cancer Driver No 1 hippie 27 100 5 5 0
RPL7L1 RPL7L1 Q6DKI1 60S ribosomal protein L7-like 1 chr6 Not Cancer Driver No 1 hippie 29 29 1 1 0
RPL8_ENST00000528957 RPL8 P62917 60S ribosomal protein L8 chr8 Not Cancer Driver No 1 hippie 32 115 17 17 0
RPL9 RPL9 Q53Z07 60S ribosomal protein L9 chr4 Not Cancer Driver No 1 hippie 30 3 0 0 0
RPS10_ENST00000467531 RPS10 P46783 40S ribosomal protein S10 chr6 Not Cancer Driver No 1 hippie 25 100 19 19 0
RPS2 RPS2 P15880 40S ribosomal protein S2 chr16 Not Cancer Driver No 1 hippie 34 85 14 14 0
RPS24_ENST00000613865 RPS24 P62847 40S ribosomal protein S24 chr10 Not Cancer Driver No 1 hippie 13 88 10 10 0
RPS29_ENST00000245458 RPS29 P62273 40S ribosomal protein S29 chr14 Not Cancer Driver No 1 hippie 7 0 0 0 2
RPS6 RPS6 P62753 40S ribosomal protein S6 chr9 Not Cancer Driver No 1 hippie 38 150 25 25 0
RREB1_ENST00000349384 RREB1 Q92766 Ras-responsive element-binding protein 1 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 213 1152 144 144 0
RRP12 RRP12 Q5JTH9 RRP12-like protein chr10 Not Cancer Driver No 1 hippie 155 336 56 56 0
RSF1 RSF1 Q96T23 Remodeling and spacing factor 1 chr11 Not Cancer Driver No 1 intact, hippie, biogrid 153 1170 130 130 0
RSL1D1 RSL1D1 O76021 Ribosomal L1 domain-containing protein 1 chr16 Not Cancer Driver No 1 intact, hippie, biogrid 61 275 33 33 0
S100A3_ENST00000368712 S100A3 P33764 Protein S100-A3 chr1 Not Cancer Driver No 3 hippie, biogrid 15 0 0 0 0
SAFB2 SAFB2 Q14151 Scaffold attachment factor B2 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 97 931 88 88 0
SAFB_ENST00000292123 SAFB Q15424 Scaffold attachment factor B1 chr19 Not Cancer Driver No 1 intact, hippie, biogrid 111 911 110 110 0
SARS2_ENST00000221431 SARS2 Q9NP81 Serine--tRNA ligase, mitochondrial chr19 Not Cancer Driver No 1 hippie, biogrid 64 111 14 14 1
SART3 SART3 Q15020 Squamous cell carcinoma antigen recognized by T-cells 3 chr12 Not Cancer Driver No 1 hippie 101 404 45 45 0
SATB1_ENST00000454909 SATB1 Q01826 DNA-binding protein SATB1 chr3 Compendium Yes 1 hippie, biogrid 130 482 84 84 12
SATB2 SATB2 Q9UPW6 DNA-binding protein SATB2 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 164 412 100 100 0
SCAF1 SCAF1 Q9H7N4 Splicing factor, arginine/serine-rich 19 chr19 Not Cancer Driver No 1 hippie 135 1307 134 134 0
SDAD1 SDAD1 Q9NVU7 Protein SDA1 homolog chr4 Not Cancer Driver No 1 hippie 65 288 29 29 0
SDC1_ENST00000254351 SDC1 P18827 Syndecan-1 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 31 259 30 30 0
SDC2 SDC2 P34741 Syndecan-2 chr8 Not Cancer Driver No 1 intact, hippie, biogrid 41 127 24 24 0
SDC4 SDC4 P31431 Syndecan-4 chr20 Census, Compendium Yes 1 hippie 34 110 25 25 0
SENP3_ENST00000429205 SENP3 Q9H4L4 Sentrin-specific protease 3 chr17 Not Cancer Driver No 1 intact, hippie, biogrid 53 288 30 30 0
SERPINB5 SERPINB5 P36952 Serpin B5 chr18 Not Cancer Driver No 1 hippie, biogrid 57 50 7 7 0
SF3A2 SF3A2 Q15428 Splicing factor 3A subunit 2 chr19 Not Cancer Driver No 1 hippie 30 382 21 21 0
SF3A3 SF3A3 Q12874 Splicing factor 3A subunit 3 chr1 Not Cancer Driver No 1 hippie 63 182 19 19 0
SF3B2 SF3B2 Q13435 Splicing factor 3B subunit 2 chr11 Not Cancer Driver No 1 hippie 110 804 105 105 0
SF3B6 SF3B6 Q9Y3B4 Splicing factor 3B subunit 6 chr2 Not Cancer Driver No 1 hippie 9 10 0 0 0
SLC16A1 SLC16A1 P53985 Monocarboxylate transporter 1 chr1 Not Cancer Driver No 1 hippie 69 70 3 3 3
SLU7 SLU7 O95391 Pre-mRNA-splicing factor SLU7 chr5 Not Cancer Driver No 1 hippie 75 436 63 63 0
SMARCA1_ENST00000371122 SMARCA1 P28370 Probable global transcription activator SNF2L1 chrX Compendium Yes 1 intact, hippie, biogrid 143 309 41 41 0
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 Census, Compendium Yes 1 hippie 349 1072 195 195 5
SMARCA5 SMARCA5 O60264 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 chr4 Not Cancer Driver No 1 intact, hippie, biogrid 116 363 48 48 0
SNRNP70 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 Not Cancer Driver No 1 hippie 38 416 37 37 0
SNRPD1 SNRPD1 P62314 Small nuclear ribonucleoprotein Sm D1 chr18 Not Cancer Driver No 1 hippie 10 80 4 4 0
SNU13_ENST00000355257 SNU13 P55769 NHP2-like protein 1 chr22 Not Cancer Driver No 1 hippie 17 2 0 0 0
SPEN SPEN Q96T58 Msx2-interacting protein chr1 Census, Compendium Yes 1 hippie 459 3061 393 393 0
SRP14 SRP14 P37108 Signal recognition particle 14 kDa protein chr15 Not Cancer Driver No 1 hippie 10 74 8 8 0
SRP72_ENST00000642900 SRP72 O76094 Signal recognition particle subunit SRP72 chr4 Not Cancer Driver No 1 hippie 79 237 22 22 1
SRPK2_ENST00000489828 SRPK2 P78362 SRSF protein kinase 2 chr7 Not Cancer Driver No 1 hippie 78 343 46 46 0
SRRM2 SRRM2 Q9UQ35 Serine/arginine repetitive matrix protein 2 chr16 Not Cancer Driver No 1 hippie, biogrid 433 2748 431 431 0
SRSF10 SRSF10 O75494 Serine/arginine-rich splicing factor 10 chr1 Not Cancer Driver No 1 hippie 2 192 1 1 0
SRSF4 SRSF4 Q08170 Serine/arginine-rich splicing factor 4 chr1 Not Cancer Driver No 1 hippie 67 409 55 55 0
SRSF9 SRSF9 Q13242 Serine/arginine-rich splicing factor 9 chr12 Not Cancer Driver No 1 hippie 20 111 8 8 0
SSRP1 SSRP1 Q08945 FACT complex subunit SSRP1 chr11 Not Cancer Driver No 1 hippie 92 308 35 35 0
STRBP_ENST00000348403 STRBP Q96SI9 Spermatid perinuclear RNA-binding protein chr9 Not Cancer Driver No 1 hippie 74 306 31 31 0
SUGP2_ENST00000452918 SUGP2 Q8IX01 SURP and G-patch domain-containing protein 2 chr19 Not Cancer Driver No 1 hippie 124 651 74 74 0
SUPT16H SUPT16H Q9Y5B9 FACT complex subunit SPT16 chr14 Not Cancer Driver No 1 hippie, biogrid 147 301 44 44 0
SUPT5H SUPT5H O00267 Transcription elongation factor SPT5 chr19 Not Cancer Driver No 1 hippie, biogrid 165 572 87 87 0
SUPT6H SUPT6H Q7KZ85 Transcription elongation factor SPT6 chr17 Not Cancer Driver No 1 hippie 222 761 107 107 0
TBL3 TBL3 Q12788 Transducin beta-like protein 3 chr16 Not Cancer Driver No 1 hippie 82 48 8 8 0
TBP TBP P20226 TATA-box-binding protein chr6 Not Cancer Driver No 1 intact, hippie, biogrid 40 164 14 14 0
TCF20 TCF20 Q9UGU0 Transcription factor 20 chr22 Not Cancer Driver No 1 intact, hippie, biogrid 234 1811 214 214 1
TCOF1 TCOF1 Q13428 Treacle protein chr5 Not Cancer Driver No 1 hippie 142 1454 141 141 1
TECR TECR Q9NZ01 Very-long-chain enoyl-CoA reductase chr19 Not Cancer Driver No 1 hippie 41 0 0 0 1
TEX10 TEX10 Q9NXF1 Testis-expressed protein 10 chr9 Not Cancer Driver No 1 intact, hippie, biogrid 115 103 12 12 0
TFAM TFAM Q00059 Transcription factor A, mitochondrial chr10 Not Cancer Driver No 1 hippie, biogrid 25 110 15 15 1
TFAP2A TFAP2A P05549 Transcription factor AP-2-alpha chr6 Not Cancer Driver No 1 hippie, biogrid 77 275 44 44 4
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 Compendium Yes 1 hippie, biogrid 61 285 52 52 0
TFIP11_ENST00000407148 TFIP11 Q9UBB9 Tuftelin-interacting protein 11 chr22 Not Cancer Driver No 1 hippie 87 331 39 39 0
TMA16 TMA16 Q96EY4 Translation machinery-associated protein 16 chr4 Not Cancer Driver No 1 hippie 25 112 10 10 0
TMEFF1 TMEFF1 Q8IYR6 Tomoregulin-1 chr9 Not Cancer Driver No 1 hippie 50 65 9 9 0
TMPO TMPO P42166 Lamina-associated polypeptide 2, isoform alpha chr12 Not Cancer Driver No 1 intact, hippie, biogrid 78 412 52 52 0
TOP2A TOP2A P11388 DNA topoisomerase 2-alpha chr17 Compendium Yes 1 hippie 150 508 59 59 0
TOP2B TOP2B Q02880 DNA topoisomerase 2-beta chr3 Not Cancer Driver No 1 hippie 154 543 46 46 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TRIM26 TRIM26 Q12899 Tripartite motif-containing protein 26 chr6 Not Cancer Driver No 3 intact, hippie, biogrid 67 153 16 16 0
TSR1 TSR1 Q2NL82 Pre-rRNA-processing protein TSR1 homolog chr17 Not Cancer Driver No 1 hippie 74 332 32 32 0
TTF2 TTF2 Q9UNY4 Transcription termination factor 2 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 118 550 50 50 0
TWNK TWNK Q96RR1 Twinkle mtDNA helicase chr10 Not Cancer Driver No 1 intact, hippie 95 135 11 11 38
U2AF1 U2AF1 Q01081 Splicing factor U2AF 35 kDa subunit chr21 Census, Compendium Yes 1 hippie, biogrid 70 73 13 13 3
U2SURP U2SURP O15042 U2 snRNP-associated SURP motif-containing protein chr3 Not Cancer Driver No 1 hippie 127 757 105 105 0
UBN1 UBN1 Q9NPG3 Ubinuclein-1 chr16 Not Cancer Driver No 1 intact, hippie, biogrid 118 943 105 105 0
UBN2 UBN2 Q6ZU65 Ubinuclein-2 chr7 Not Cancer Driver No 1 intact, hippie, biogrid 157 1104 126 126 0
UBR5 UBR5 O95071 E3 ubiquitin-protein ligase UBR5 chr8 Census, Compendium Yes 1 hippie 340 1296 162 162 0
UBTF UBTF P17480 Nucleolar transcription factor 1 chr17 Not Cancer Driver No 1 hippie 100 567 77 77 1
UCHL1 UCHL1 P09936 Ubiquitin carboxyl-terminal hydrolase isozyme L1 chr4 Not Cancer Driver No 1 hippie, biogrid 33 34 7 7 4
UPF1 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 Not Cancer Driver No 1 hippie 146 329 36 36 0
USP11 USP11 P51784 Ubiquitin carboxyl-terminal hydrolase 11 chrX Not Cancer Driver No 1 hippie 140 210 28 28 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 Not Cancer Driver No 1 intact, hippie, biogrid 170 215 45 45 0
UTP14A UTP14A Q9BVJ6 U3 small nucleolar RNA-associated protein 14 homolog A chrX Not Cancer Driver No 1 hippie 105 629 89 89 0
VCAN VCAN P13611 Versican core protein chr5 Not Cancer Driver No 1 hippie 647 2643 483 483 0
VSIG8 VSIG8 P0DPA2 V-set and immunoglobulin domain-containing protein 8 chr1 Not Cancer Driver No 3 intact, biogrid 39 15 0 0 0
WBP11 WBP11 Q9Y2W2 WW domain-binding protein 11 chr12 Not Cancer Driver No 1 hippie 86 606 79 79 0
WDR12 WDR12 Q9GZL7 Ribosome biogenesis protein WDR12 chr2 Not Cancer Driver No 1 hippie 39 36 1 1 0
WDR18 WDR18 Q9BV38 WD repeat-containing protein 18 chr19 Not Cancer Driver No 1 hippie 38 60 2 2 0
WDR33 WDR33 Q9C0J8 pre-mRNA 3' end processing protein WDR33 chr2 Not Cancer Driver No 1 hippie 191 987 153 153 0
WDR61 WDR61 Q9GZS3 WD repeat-containing protein 61 chr15 Not Cancer Driver No 1 hippie 25 7 1 1 0
WDR83 WDR83 Q9BRX9 WD repeat domain-containing protein 83 chr19 Not Cancer Driver No 1 hippie 28 35 3 3 0
WIZ_ENST00000263381 WIZ O95785-2 Isoform 2 of Protein Wiz chr19 Not Cancer Driver No 1 hippie 148 651 135 135 0
WRNIP1 WRNIP1 Q96S55 ATPase WRNIP1 chr6 Not Cancer Driver No 1 hippie 50 292 7 7 0
WTAP_ENST00000621533 WTAP Q15007 Pre-mRNA-splicing regulator WTAP chr6 Not Cancer Driver No 1 hippie 60 305 50 50 0
XAB2 XAB2 Q9HCS7 Pre-mRNA-splicing factor SYF1 chr19 Not Cancer Driver No 1 hippie 128 127 17 17 0
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 Not Cancer Driver No 1 intact, hippie, biogrid 87 118 11 11 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 Not Cancer Driver No 1 intact, hippie, biogrid 66 140 12 12 0
XRN2 XRN2 Q9H0D6 5'-3' exoribonuclease 2 chr20 Not Cancer Driver No 1 hippie 129 427 63 63 0
XYLT2 XYLT2 Q9H1B5 Xylosyltransferase 2 chr17 Not Cancer Driver No 1 hippie 85 264 28 28 1
YTHDC1_ENST00000344157 YTHDC1 Q96MU7 YTH domain-containing protein 1 chr4 Not Cancer Driver No 1 hippie 137 597 117 117 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 Not Cancer Driver No 1 intact, hippie, biogrid 26 77 9 9 2
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 Not Cancer Driver No 1 intact, hippie, biogrid 15 55 3 3 0
ZBTB44_ENST00000357899 ZBTB44 Q8NCP5 Zinc finger and BTB domain-containing protein 44 chr11 Not Cancer Driver No 1 hippie, biogrid 68 266 35 35 0
ZC3H14 ZC3H14 Q6PJT7 Zinc finger CCCH domain-containing protein 14 chr14 Not Cancer Driver No 1 hippie 96 542 68 68 0
ZC3H18_ENST00000301011 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 1 hippie 139 929 134 134 0
ZCCHC3 ZCCHC3 Q9NUD5 Zinc finger CCHC domain-containing protein 3 chr20 Not Cancer Driver No 1 hippie 28 160 1 1 0
ZCCHC8 ZCCHC8 Q6NZY4 Zinc finger CCHC domain-containing protein 8 chr12 Census Yes 1 hippie 81 503 56 56 1
ZMYM2_ENST00000382871 ZMYM2 Q9UBW7 Zinc finger MYM-type protein 2 chr13 Census Yes 1 hippie, biogrid 144 583 68 68 0
ZMYM4 ZMYM4 Q5VZL5 Zinc finger MYM-type protein 4 chr1 Not Cancer Driver No 1 intact, hippie, biogrid 159 660 53 53 0
ZNF148_ENST00000485866 ZNF148 Q9UQR1 Zinc finger protein 148 chr3 Compendium Yes 1 hippie, biogrid 125 600 88 88 0
ZNF280C ZNF280C Q8ND82 Zinc finger protein 280C chrX Not Cancer Driver No 1 hippie 91 390 42 42 0
ZNF326 ZNF326 Q5BKZ1 DBIRD complex subunit ZNF326 chr1 Not Cancer Driver No 1 hippie 64 490 53 53 0
ZNF384 ZNF384 Q8TF68 Zinc finger protein 384 chr12 Census Yes 1 intact, hippie, biogrid 63 403 44 44 0
ZNF428 ZNF428 Q96B54 Zinc finger protein 428 chr19 Not Cancer Driver No 1 hippie, biogrid 23 188 23 23 0
ZNF622 ZNF622 Q969S3 Zinc finger protein 622 chr5 Not Cancer Driver No 1 hippie 66 220 33 33 0
ZNF646 ZNF646 O15015 Zinc finger protein 646 chr16 Not Cancer Driver No 1 hippie, biogrid 228 1410 173 173 0
ZNF687 ZNF687 Q8N1G0 Zinc finger protein 687 chr1 Not Cancer Driver No 1 hippie 138 776 83 83 1
ZNF711_ENST00000373165 ZNF711 Q9Y462 Zinc finger protein 711 chrX Not Cancer Driver No 1 intact, hippie, biogrid 192 357 75 75 1