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PYGO2 ,PYGO2 ,Q9BRQ0
  • Uniprot Accession= Q9BRQ0
  • Ensembl Transcript= ENST00000368457.2
  • Uniprot Name= PYGO2
  • Name= Pygopus homolog 2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 21
  • Number of Interaction partner in biogrid: 7
  • Number of Interaction partner in hippie: 46
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 Census, Compendium Yes 1 hippie 108 158 24 24 4
AR AR P10275 Androgen receptor chrX Census, Compendium Yes 1 hippie, biogrid 196 443 88 88 169
ASH2L ASH2L Q9UBL3 Set1/Ash2 histone methyltransferase complex subunit ASH2 chr8 Not Cancer Driver No 1 hippie 95 293 39 39 0
BCL9 BCL9 O00512 B-cell CLL/lymphoma 9 protein chr1 Census, Compendium Yes 2 hippie, biogrid 219 1426 219 219 0
BCL9L BCL9L Q86UU0 B-cell CLL/lymphoma 9-like protein chr11 Census, Compendium Yes 2 intact, hippie, biogrid 200 1495 200 200 0
CDC73 CDC73 Q6P1J9 Parafibromin chr1 Census, Compendium Yes 1 intact, hippie 110 210 39 39 2
CREBBP CREBBP Q92793 CREB-binding protein chr16 Census, Compendium Yes 1 hippie 412 1796 247 247 33
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
CUL4A CUL4A Q13619 Cullin-4A chr13 Not Cancer Driver No 1 hippie 64 102 2 2 0
DCAF1 DCAF1 Q9Y4B6 DDB1- and CUL4-associated factor 1 chr3 Not Cancer Driver No 1 hippie 128 495 44 44 0
EPS15 EPS15 P42566 Epidermal growth factor receptor substrate 15 chr1 Census, Compendium Yes 1 intact 106 543 66 66 0
ERG_ENST00000288319 ERG P11308 Transcriptional regulator ERG chr21 Census, Compendium Yes 1 intact, hippie 95 296 54 54 0
ETV4_ENST00000591713 ETV4 P43268 ETS translocation variant 4 chr17 Census, Compendium Yes 1 hippie 44 319 26 26 0
GRHPR GRHPR Q9UBQ7 Glyoxylate reductase/hydroxypyruvate reductase chr9 Not Cancer Driver No 1 hippie, biogrid 31 36 4 4 0
HNRNPH1 HNRNPH1 P31943 Heterogeneous nuclear ribonucleoprotein H chr5 Not Cancer Driver No 1 hippie 51 169 29 29 0
IRF4 IRF4 Q15306 Interferon regulatory factor 4 chr6 Census, Compendium Yes 1 hippie 99 155 45 45 0
JRK_ENST00000571961 JRK O75564 Jerky protein homolog chr8 Not Cancer Driver No 1 intact, hippie 56 140 17 17 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 Not Cancer Driver No 1 hippie 88 251 17 17 0
KLC2_ENST00000394067 KLC2 Q9H0B6 Kinesin light chain 2 chr11 Not Cancer Driver No 1 hippie, biogrid 75 344 49 49 0
KLF15 KLF15 Q9UIH9 Krueppel-like factor 15 chr3 Not Cancer Driver No 1 hippie 66 273 48 48 0
KMT2D KMT2D O14686 Histone-lysine N-methyltransferase 2D chr12 Census, Compendium Yes 1 hippie 773 4386 552 552 13
KSR2_ENST00000339824 KSR2 Q6VAB6 Kinase suppressor of Ras 2 chr12 Not Cancer Driver No 1 intact, hippie 231 434 120 120 0
LHX3_ENST00000371748 LHX3 Q9UBR4 LIM/homeobox protein Lhx3 chr9 Not Cancer Driver No 1 intact, hippie 38 232 14 14 2
LHX4 LHX4 Q969G2 LIM/homeobox protein Lhx4 chr1 Not Cancer Driver No 1 intact, hippie 75 219 45 45 4
LHX8 LHX8 Q68G74 LIM/homeobox protein Lhx8 chr1 Not Cancer Driver No 1 intact, hippie 93 157 47 47 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 Not Cancer Driver No 1 hippie 110 101 8 8 0
NF2 NF2 P35240 Merlin chr22 Census, Compendium Yes 1 hippie 69 252 26 26 16
NXF1_ENST00000294172 NXF1 Q9UBU9 Nuclear RNA export factor 1 chr11 Compendium Yes 1 hippie 100 163 32 32 0
PAX7_ENST00000420770 PAX7 P23759 Paired box protein Pax-7 chr1 Census Yes 1 intact, hippie 97 401 77 77 1
PAX8 PAX8 Q06710 Paired box protein Pax-8 chr2 Census Yes 1 intact, hippie 84 291 55 55 4
PAX9 PAX9 P55771 Paired box protein Pax-9 chr14 Not Cancer Driver No 1 intact, hippie 52 198 32 32 1
PYGO2 PYGO2 Q9BRQ0 Pygopus homolog 2 chr1 Not Cancer Driver No 1 hippie 51 340 43 43 0
RAVER1_ENST00000615032 RAVER1 Q8IY67 Ribonucleoprotein PTB-binding 1 chr19 Not Cancer Driver No 1 intact 61 330 22 22 0
RBBP5 RBBP5 Q15291 Retinoblastoma-binding protein 5 chr1 Not Cancer Driver No 1 hippie 57 218 19 19 0
SORCS3 SORCS3 Q9UPU3 VPS10 domain-containing receptor SorCS3 chr10 Not Cancer Driver No 1 intact, hippie 405 221 13 13 0
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 intact, hippie 39 312 39 39 0
SOX5 SOX5 P35711 Transcription factor SOX-5 chr12 Not Cancer Driver No 1 intact, hippie 182 665 162 162 0
SOX6_ENST00000528429 SOX6 P35712 Transcription factor SOX-6 chr11 Not Cancer Driver No 1 intact, hippie 130 744 118 118 0
SP7 SP7 Q8TDD2 Transcription factor Sp7 chr12 Not Cancer Driver No 1 intact, hippie 63 332 44 44 0
SUPT3H_ENST00000371459 SUPT3H O75486 Transcription initiation protein SPT3 homolog chr6 Not Cancer Driver No 1 hippie 49 49 4 4 0
TBR1 TBR1 Q16650 T-box brain protein 1 chr2 Not Cancer Driver No 1 hippie 88 413 56 56 5
TLX1 TLX1 P31314 T-cell leukemia homeobox protein 1 chr10 Census Yes 1 intact, hippie 28 223 17 17 0
TLX2 TLX2 O43763 T-cell leukemia homeobox protein 2 chr2 Not Cancer Driver No 1 intact, hippie 24 220 15 15 0
TLX3 TLX3 O43711 T-cell leukemia homeobox protein 3 chr5 Census Yes 1 intact, hippie 40 179 24 24 0
TPI1_ENST00000396705 TPI1 P60174 Triosephosphate isomerase chr12 Not Cancer Driver No 1 hippie, biogrid 40 15 2 2 7
TRIP6 TRIP6 Q15654 Thyroid receptor-interacting protein 6 chr7 Not Cancer Driver No 1 hippie, biogrid 62 268 19 19 0
TRRAP TRRAP Q9Y4A5 Transformation/transcription domain-associated protein chr7 Census, Compendium Yes 1 hippie 554 402 59 59 8
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie 30 35 3 3 0