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PTPRU ,PTPRU ,Q92729
  • Uniprot Accession= Q92729
  • Ensembl Transcript= ENST00000345512.7
  • Uniprot Name= PTPRU
  • Name= Receptor-type tyrosine-protein phosphatase U
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 11
  • Number of Interaction partner in biogrid: 46
  • Number of Interaction partner in hippie: 109
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAMP_ENST00000248450 AAMP Q13685 Angio-associated migratory cell protein chr2 Not Cancer Driver No 3 intact, hippie, biogrid 31 126 10 10 0
ABI2_ENST00000261018 ABI2 Q9NYB9 Abl interactor 2 chr2 Not Cancer Driver No 1 hippie 56 361 38 38 0
AFDN_ENST00000447894 AFDN P55196 Afadin chr6 Census Yes 1 hippie 248 1247 180 180 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 1 hippie 34 103 14 14 0
ARHGAP5 ARHGAP5 Q13017 Rho GTPase-activating protein 5 chr14 Census, Compendium Yes 1 hippie 249 418 50 50 0
ARL2 ARL2 P36404 ADP-ribosylation factor-like protein 2 chr11 Not Cancer Driver No 1 hippie 19 0 0 0 1
ASIC4_ENST00000358078 ASIC4 A0A8I5KPF5 Acid-sensing ion channel 4 chr2 Not Cancer Driver No 1 hippie, biogrid 121 249 35 35 0
BTNL2_ENST00000374993 BTNL2 Q9UIR0 Butyrophilin-like protein 2 chr6 Not Cancer Driver No 1 hippie, biogrid 66 82 16 16 0
C1QB C1QB P02746 Complement C1q subcomponent subunit B chr1 Not Cancer Driver No 1 hippie, biogrid 46 133 31 31 1
CA10_ENST00000285273 CA10 Q9NS85 Carbonic anhydrase-related protein 10 chr17 Not Cancer Driver No 1 hippie, biogrid 103 9 1 1 0
CALR CALR P27797 Calreticulin chr19 Census Yes 1 hippie 45 245 31 31 0
CANX_ENST00000504734 CANX P27824 Calnexin chr5 Not Cancer Driver No 1 hippie 65 334 38 38 0
CBLN4 CBLN4 Q9NTU7 Cerebellin-4 chr20 Not Cancer Driver No 1 hippie, biogrid 62 20 10 10 0
CDH5 CDH5 P33151 Cadherin-5 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 144 305 55 55 0
CDHR4 CDHR4 A6H8M9 Cadherin-related family member 4 chr3 Not Cancer Driver No 1 hippie, biogrid 54 111 4 4 0
CKAP5 CKAP5 Q14008 Cytoskeleton-associated protein 5 chr11 Not Cancer Driver No 1 hippie 198 634 64 64 0
CLEC12B CLEC12B Q2HXU8 C-type lectin domain family 12 member B chr12 Not Cancer Driver No 1 hippie, biogrid 34 57 8 8 0
CLEC2D_ENST00000290855 CLEC2D Q9UHP7 C-type lectin domain family 2 member D chr12 Not Cancer Driver No 2 intact, hippie, biogrid 28 14 1 1 0
CLGN_ENST00000414773 CLGN O14967 Calmegin chr4 Not Cancer Driver No 1 hippie, biogrid 86 255 36 36 0
CSE1L CSE1L P55060 Exportin-2 chr20 Not Cancer Driver No 1 hippie 109 32 5 5 0
CTLA4 CTLA4 P16410 Cytotoxic T-lymphocyte protein 4 chr2 Not Cancer Driver No 1 hippie, biogrid 37 3 0 0 1
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 Census Yes 1 hippie 126 268 35 35 4
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
DDOST_ENST00000375048 DDOST P39656 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit chr1 Not Cancer Driver No 1 hippie 34 13 3 3 1
DHFR2_ENST00000314636 DHFR2 Q86XF0 Dihydrofolate reductase 2, mitochondrial chr3 Not Cancer Driver No 1 hippie 25 20 0 0 0
DNAJB11_ENST00000265028 DNAJB11 Q9UBS4 DnaJ homolog subfamily B member 11 chr3 Not Cancer Driver No 1 hippie 52 141 21 21 2
DNAJB9 DNAJB9 Q9UBS3 DnaJ homolog subfamily B member 9 chr7 Not Cancer Driver No 1 hippie, biogrid 30 107 15 15 0
DNAJC10 DNAJC10 Q8IXB1 DnaJ homolog subfamily C member 10 chr2 Not Cancer Driver No 1 hippie 110 36 3 3 0
DNAJC16 DNAJC16 Q9Y2G8 DnaJ homolog subfamily C member 16 chr1 Not Cancer Driver No 1 hippie 84 63 2 2 0
DSG2 DSG2 Q14126 Desmoglein-2 chr18 Not Cancer Driver No 1 hippie 173 476 68 68 5
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 1 hippie 275 314 41 41 1
FAM19A2_ENST00000551619 TAFA2 Q8N3H0 Chemokine-like protein TAFA-2 chr12 Not Cancer Driver No 1 hippie 55 4 1 1 0
FAM19A4 TAFA4 Q96LR4 Chemokine-like protein TAFA-4 chr3 Not Cancer Driver No 1 intact, hippie 38 4 1 1 0
FBXO2 FBXO2 Q9UK22 F-box only protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 21 75 1 1 0
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie, biogrid 31 27 3 3 0
FIBIN FIBIN Q8TAL6 Fin bud initiation factor homolog chr11 Not Cancer Driver No 1 hippie, biogrid 42 51 12 12 0
FUT8_ENST00000394586 FUT8 Q9BYC5 Alpha-(1,6)-fucosyltransferase chr14 Not Cancer Driver No 1 hippie 79 80 19 19 1
GANAB_ENST00000356638 GANAB Q14697 Neutral alpha-glucosidase AB chr11 Not Cancer Driver No 1 hippie 129 132 20 20 3
GNAI1 GNAI1 P63096 Guanine nucleotide-binding protein G(i) subunit alpha-1 chr7 Not Cancer Driver No 1 hippie 52 11 3 3 0
GNAI2 GNAI2 P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 chr3 Compendium Yes 1 hippie 50 24 0 0 0
GNAI3 GNAI3 P08754 Guanine nucleotide-binding protein G(i) subunit alpha-3 chr1 Not Cancer Driver No 1 hippie 42 11 0 0 1
GNAO1_ENST00000638705 GNAO1 P09471 Guanine nucleotide-binding protein G(o) subunit alpha chr16 Not Cancer Driver No 1 hippie 54 10 0 0 15
GOLIM4 GOLIM4 O00461 Golgi integral membrane protein 4 chr3 Not Cancer Driver No 2 hippie, biogrid 93 612 89 89 0
GPIHBP1 GPIHBP1 Q8IV16 Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 chr8 Not Cancer Driver No 1 hippie, biogrid 26 82 15 15 10
GRAMD1A GRAMD1A Q96CP6 Protein Aster-A chr19 Not Cancer Driver No 1 hippie 83 261 33 33 0
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 Not Cancer Driver No 1 hippie, biogrid 55 27 2 2 11
HLA-DRA HLA-DRA P01903 HLA class II histocompatibility antigen, DR alpha chain chr6 Not Cancer Driver No 1 hippie, biogrid 52 12 1 1 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 Not Cancer Driver No 1 hippie, biogrid 94 85 22 22 0
IL5RA_ENST00000256452 IL5RA Q01344 Interleukin-5 receptor subunit alpha chr3 Not Cancer Driver No 1 hippie, biogrid 92 23 5 5 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 Not Cancer Driver No 1 hippie 161 1072 133 133 2
KIAA0556 KATNIP O60303 Katanin-interacting protein chr16 Not Cancer Driver No 1 intact 240 982 137 137 0
KIF7 KIF7 Q2M1P5 Kinesin-like protein KIF7 chr15 Not Cancer Driver No 1 hippie 150 844 104 104 5
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 Census, Compendium Yes 1 hippie 226 83 33 33 21
KLRC1 KLRC1 P26715 NKG2-A/NKG2-B type II integral membrane protein chr12 Not Cancer Driver No 1 hippie, biogrid 49 49 10 10 0
LEMD3 LEMD3 Q9Y2U8 Inner nuclear membrane protein Man1 chr12 Not Cancer Driver No 1 hippie 78 509 33 33 0
LY86 LY86 O95711 Lymphocyte antigen 86 chr6 Not Cancer Driver No 1 hippie, biogrid 29 0 0 0 0
MACO1 MACO1 Q8N5G2 Macoilin chr1 Not Cancer Driver No 1 hippie 79 407 52 52 0
MFAP4_ENST00000299610 MFAP4 P55083 Microfibril-associated glycoprotein 4 chr17 Not Cancer Driver No 1 hippie, biogrid 35 0 0 0 0
MON2 MON2 Q7Z3U7 Protein MON2 homolog chr12 Not Cancer Driver No 1 hippie 201 151 16 16 0
NCR3 NCR3 O14931 Natural cytotoxicity triggering receptor 3 chr6 Not Cancer Driver No 1 hippie, biogrid 26 31 2 2 0
NHS NHS Q6T4R5 Nance-Horan syndrome protein chrX Not Cancer Driver No 1 hippie 277 1515 254 254 0
NHSL1 NHSL1 Q5SYE7 NHS-like protein 1 chr6 Not Cancer Driver No 1 hippie 60 1535 58 58 0
NOMO1 NOMO1 Q15155 Nodal modulator 1 chr16 Not Cancer Driver No 1 hippie 130 128 23 23 0
NRSN1 NRSN1 Q8IZ57 Neurensin-1 chr6 Not Cancer Driver No 1 hippie, biogrid 46 17 9 9 0
NUP210 NUP210 Q8TEM1 Nuclear pore membrane glycoprotein 210 chr3 Not Cancer Driver No 1 hippie 262 156 19 19 0
NXPH3 NXPH3 O95157 Neurexophilin-3 chr17 Not Cancer Driver No 1 hippie, biogrid 39 82 14 14 0
OPA1_ENST00000392438 OPA1 O60313 Dynamin-like 120 kDa protein, mitochondrial chr3 Not Cancer Driver No 1 hippie 114 131 17 17 60
P4HB P4HB P07237 Protein disulfide-isomerase chr17 Not Cancer Driver No 1 hippie 61 79 15 15 1
PCDH20 PCDH20 Q8N6Y1 Protocadherin-20 chr13 Not Cancer Driver No 1 hippie, biogrid 228 159 30 30 0
PCDHB3 PCDHB3 Q9Y5E6 Protocadherin beta-3 chr5 Not Cancer Driver No 1 hippie, biogrid 258 119 30 30 0
PCDHB7 PCDHB7 Q9Y5E2 Protocadherin beta-7 chr5 Not Cancer Driver No 1 hippie, biogrid 354 128 58 58 0
PCDHGB1 PCDHGB1 Q9Y5G3 Protocadherin gamma-B1 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 220 329 61 61 0
PCDHGB4 PCDHGB4 Q9UN71 Protocadherin gamma-B4 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 211 330 83 83 0
PCDHGC5 PCDHGC5 Q9Y5F6 Protocadherin gamma-C5 chr5 Not Cancer Driver No 1 hippie, biogrid 135 492 72 72 0
PDIA3 PDIA3 P30101 Protein disulfide-isomerase A3 chr15 Not Cancer Driver No 1 hippie 57 98 11 11 0
PDIA4 PDIA4 P13667 Protein disulfide-isomerase A4 chr7 Not Cancer Driver No 1 hippie 81 147 22 22 0
PDIA6_ENST00000272227 PDIA6 Q15084 Protein disulfide-isomerase A6 chr2 Not Cancer Driver No 1 hippie 55 82 11 11 0
PI15 PI15 O43692 Peptidase inhibitor 15 chr8 Not Cancer Driver No 1 hippie, biogrid 87 4 1 1 0
PLOD1 PLOD1 Q02809 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 chr1 Not Cancer Driver No 1 hippie 86 12 0 0 5
PPFIA3 PPFIA3 O75145 Liprin-alpha-3 chr19 Not Cancer Driver No 1 hippie 140 831 107 107 0
PRG2 PRG2 P13727 Bone marrow proteoglycan chr11 Not Cancer Driver No 1 hippie, biogrid 45 65 15 15 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 Not Cancer Driver No 1 hippie 538 421 61 61 2
PRRC2A_ENST00000376007 PRRC2A P48634 Protein PRRC2A chr6 Not Cancer Driver No 1 hippie 253 2119 249 249 0
PRRC2B PRRC2B Q5JSZ5 Protein PRRC2B chr9 Not Cancer Driver No 1 hippie 279 2199 278 278 0
PSMD1 PSMD1 Q99460 26S proteasome non-ATPase regulatory subunit 1 chr2 Not Cancer Driver No 1 hippie 110 201 19 19 0
PSMD12 PSMD12 O00232 26S proteasome non-ATPase regulatory subunit 12 chr17 Not Cancer Driver No 1 hippie 48 24 3 3 0
PSMD13_ENST00000532097 PSMD13 Q9UNM6 26S proteasome non-ATPase regulatory subunit 13 chr11 Not Cancer Driver No 1 hippie 30 13 3 3 0
PTPRK_ENST00000368215 PTPRK Q15262 Receptor-type tyrosine-protein phosphatase kappa chr6 Census, Compendium Yes 1 intact, hippie, biogrid 292 302 57 57 0
PTPRU PTPRU Q92729 Receptor-type tyrosine-protein phosphatase U chr1 Not Cancer Driver No 1 intact, hippie 248 325 64 64 0
RPL10_ENST00000369817 RPL10 P27635 60S ribosomal protein L10 chrX Census, Compendium Yes 1 hippie, biogrid 46 9 3 3 4
SCGB1D1 SCGB1D1 O95968 Secretoglobin family 1D member 1 chr11 Not Cancer Driver No 2 intact, hippie, biogrid 22 0 0 0 0
SDF2L1 SDF2L1 Q9HCN8 Stromal cell-derived factor 2-like protein 1 chr22 Not Cancer Driver No 1 hippie, biogrid 16 130 9 9 0
SGCA SGCA Q16586 Alpha-sarcoglycan chr17 Not Cancer Driver No 3 hippie, biogrid 58 82 9 9 29
SIRPD SIRPD Q9H106 Signal-regulatory protein delta chr20 Not Cancer Driver No 1 hippie, biogrid 58 66 17 17 0
ST7 ST7 Q9NRC1 Suppressor of tumorigenicity 7 protein chr7 Not Cancer Driver No 1 hippie 62 64 5 5 0
ST8SIA4 ST8SIA4 Q92187 CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase chr5 Not Cancer Driver No 1 hippie, biogrid 95 5 1 1 0
TELO2 TELO2 Q9Y4R8 Telomere length regulation protein TEL2 homolog chr16 Not Cancer Driver No 1 hippie 113 154 23 23 5
TMEM106A TMEM106A Q96A25 Transmembrane protein 106A chr17 Not Cancer Driver No 1 hippie, biogrid 26 9 1 1 0
TMEM98 TMEM98 Q9Y2Y6 Transmembrane protein 98 chr17 Not Cancer Driver No 1 hippie, biogrid 39 27 3 3 2
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TRMT10C TRMT10C Q7L0Y3 tRNA methyltransferase 10 homolog C chr3 Not Cancer Driver No 1 hippie 56 59 10 10 2
UBE3C UBE3C Q15386 Ubiquitin-protein ligase E3C chr7 Not Cancer Driver No 1 hippie 143 65 12 12 0
UGGT1 UGGT1 Q9NYU2 UDP-glucose:glycoprotein glucosyltransferase 1 chr2 Not Cancer Driver No 1 hippie 169 161 20 20 0
UNC45A UNC45A Q9H3U1 Protein unc-45 homolog A chr15 Not Cancer Driver No 1 hippie 78 128 4 4 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 88 186 16 16 16
VEGFD VEGFD O43915 Vascular endothelial growth factor D chrX Not Cancer Driver No 1 hippie 59 33 6 6 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
ZNRF4 ZNRF4 Q8WWF5 E3 ubiquitin-protein ligase ZNRF4 chr19 Not Cancer Driver No 2 intact, hippie, biogrid 115 99 26 26 0