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PTPRC ,PTPRC ,P08575
  • Uniprot Accession= P08575
  • Ensembl Transcript= ENST00000442510.7
  • Uniprot Name= PTPRC
  • Name= Receptor-type tyrosine-protein phosphatase C
  • Chromosome= chr1
  • Driver status= Census, Compendium
  • Number of Interaction partner in intact: 16
  • Number of Interaction partner in biogrid: 1
  • Number of Interaction partner in hippie: 61
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 Not Cancer Driver No 1 hippie 79 239 25 25 1
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 Census, Compendium Yes 1 hippie 115 512 56 56 4
CD177 CD177 Q8N6Q3 CD177 antigen chr19 Not Cancer Driver No 1 hippie 71 79 26 26 0
CD1D CD1D P15813 Antigen-presenting glycoprotein CD1d chr1 Not Cancer Driver No 1 hippie 93 19 7 7 0
CD2 CD2 P06729 T-cell surface antigen CD2 chr1 Not Cancer Driver No 1 hippie 75 126 35 35 0
CD22 CD22 P20273 B-cell receptor CD22 chr19 Not Cancer Driver No 2 intact, hippie 173 290 66 66 0
CD244 CD244 Q9BZW8 Natural killer cell receptor 2B4 chr1 Not Cancer Driver No 1 hippie 77 92 22 22 0
CD247 CD247 P20963 T-cell surface glycoprotein CD3 zeta chain chr1 Not Cancer Driver No 1 hippie 33 91 24 24 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 Not Cancer Driver No 1 hippie 69 56 11 11 0
CD44 CD44 P16070 CD44 antigen chr11 Not Cancer Driver No 1 hippie 75 542 60 60 0
CD79A CD79A P11912 B-cell antigen receptor complex-associated protein alpha chain chr19 Census Yes 1 hippie 32 28 3 3 0
CD79B_ENST00000006750 CD79B P40259 B-cell antigen receptor complex-associated protein beta chain chr17 Census, Compendium Yes 1 hippie 25 43 10 10 1
CD8A_ENST00000283635 CD8A P01732 T-cell surface glycoprotein CD8 alpha chain chr2 Not Cancer Driver No 1 hippie 33 28 2 2 1
CDH2 CDH2 P19022 Cadherin-2 chr18 Not Cancer Driver No 1 intact, hippie 238 461 130 130 7
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 Not Cancer Driver No 2 intact, hippie 41 18 1 1 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 Census, Compendium Yes 1 hippie 415 288 301 301 14
CXCR4_ENST00000241393 CXCR4 P61073 C-X-C chemokine receptor type 4 chr2 Census, Compendium Yes 1 hippie 62 5 1 1 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EPOR EPOR P19235 Erythropoietin receptor chr19 Not Cancer Driver No 1 intact, hippie 41 120 11 11 1
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 1 hippie 275 314 41 41 1
FBXO6 FBXO6 Q9NRD1 F-box only protein 6 chr1 Not Cancer Driver No 1 hippie 31 27 3 3 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 92 70 13 13 0
GAB1_ENST00000262994 GAB1 Q13480 GRB2-associated-binding protein 1 chr4 Not Cancer Driver No 1 hippie 79 570 68 68 1
GANAB_ENST00000356638 GANAB Q14697 Neutral alpha-glucosidase AB chr11 Not Cancer Driver No 1 hippie 129 132 20 20 3
GHR_ENST00000612382 GHR P10912 Growth hormone receptor chr5 Not Cancer Driver No 1 hippie 173 229 66 66 19
GRIN2B GRIN2B Q13224 Glutamate receptor ionotropic, NMDA 2B chr12 Not Cancer Driver No 1 intact, hippie 413 426 147 147 11
INSR INSR P06213 Insulin receptor chr19 Not Cancer Driver No 1 intact, hippie 190 280 57 57 64
ITGAL ITGAL P20701 Integrin alpha-L chr16 Not Cancer Driver No 1 intact, hippie 196 144 25 25 0
KLK10_ENST00000358789 KLK10 O43240 Kallikrein-10 chr19 Not Cancer Driver No 1 hippie, biogrid 35 30 8 8 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 Census Yes 1 hippie 86 94 13 13 1
LEPR LEPR P48357 Leptin receptor chr1 Not Cancer Driver No 1 hippie 243 57 11 11 0
LGALS1 LGALS1 P09382 Galectin-1 chr22 Not Cancer Driver No 1 hippie 16 0 0 0 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 Census Yes 1 hippie 95 84 12 12 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 Not Cancer Driver No 1 hippie 39 25 1 1 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 Census, Compendium Yes 1 hippie 62 2 0 0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 Not Cancer Driver No 1 hippie 38 49 5 5 0
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 Census, Compendium Yes 1 intact, hippie 226 62 15 15 19
NSF NSF P46459 Vesicle-fusing ATPase chr17 Not Cancer Driver No 1 hippie 47 84 3 3 2
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 Census, Compendium Yes 1 intact, hippie 168 57 8 8 25
PAEP_ENST00000277508 PAEP P09466 Glycodelin chr9 Not Cancer Driver No 1 hippie 23 3 0 0 0
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 Census, Compendium Yes 1 hippie 164 231 44 44 7
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 Not Cancer Driver No 1 intact, hippie 33 121 12 12 0
PKP4 PKP4 Q99569 Plakophilin-4 chr2 Not Cancer Driver No 1 hippie 172 756 119 119 0
PLK3 PLK3 Q9H4B4 Serine/threonine-protein kinase PLK3 chr1 Not Cancer Driver No 1 hippie 75 202 15 15 0
PRKCSH_ENST00000589838 PRKCSH P14314 Glucosidase 2 subunit beta chr19 Not Cancer Driver No 1 hippie 68 320 41 41 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 Census, Compendium Yes 1 intact, hippie 315 462 107 107 0
PTPRCAP PTPRCAP Q14761 Protein tyrosine phosphatase receptor type C-associated protein chr11 Not Cancer Driver No 1 hippie 21 120 16 16 0
PXN_ENST00000228307 PXN P49023 Paxillin chr12 Not Cancer Driver No 1 intact, hippie 62 341 24 24 0
RMC1 RMC1 Q96DM3 Regulator of MON1-CCZ1 complex chr18 Not Cancer Driver No 1 hippie 70 12 0 0 0
RNF11 RNF11 Q9Y3C5 RING finger protein 11 chr1 Not Cancer Driver No 1 hippie 17 76 7 7 0
SEMA4D SEMA4D Q92854 Semaphorin-4D chr9 Not Cancer Driver No 2 intact, hippie 117 132 15 15 0
SKAP1_ENST00000584924 SKAP1 Q86WV1 Src kinase-associated phosphoprotein 1 chr17 Not Cancer Driver No 1 hippie 67 130 27 27 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 Not Cancer Driver No 1 hippie 82 64 10 10 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 Census Yes 1 hippie 53 130 11 11 1
TEC TEC P42680 Tyrosine-protein kinase Tec chr4 Census, Compendium Yes 1 hippie 91 57 15 15 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 Not Cancer Driver No 1 intact, hippie 219 126 22 22 10
TIE1 TIE1 P35590 Tyrosine-protein kinase receptor Tie-1 chr1 Not Cancer Driver No 1 intact, hippie 200 223 46 46 0
TNK2_ENST00000333602 TNK2 Q07912 Activated CDC42 kinase 1 chr3 Not Cancer Driver No 1 hippie 137 593 81 81 0
U2AF2 U2AF2 P26368 Splicing factor U2AF 65 kDa subunit chr19 Compendium Yes 1 hippie 78 191 28 28 0
UHRF2 UHRF2 Q96PU4 E3 ubiquitin-protein ligase UHRF2 chr9 Not Cancer Driver No 1 hippie 88 253 22 22 0
WAS WAS P42768 Wiskott-Aldrich syndrome protein chrX Census, Compendium Yes 1 intact, hippie 75 400 55 55 30