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PTGER3_ENST00000370931 ,PTGER3 ,P43115
  • Uniprot Accession= P43115
  • Ensembl Transcript= ENST00000370931.7
  • Uniprot Name= PTGER3
  • Name= Prostaglandin E2 receptor EP3 subtype
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 45
  • Number of Interaction partner in biogrid: 90
  • Number of Interaction partner in hippie: 117
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
ACVR2A_ENST00000404590 ACVR2A P27037 Activin receptor type-2A chr2 Census, Compendium Yes 3 intact, hippie, biogrid 98 56 6 6 0
ACVR2B ACVR2B Q13705 Activin receptor type-2B chr3 Not Cancer Driver No 3 hippie, biogrid 83 70 14 14 2
ADAMTSL4_ENST00000369038 ADAMTSL4 Q6UY14 ADAMTS-like protein 4 chr1 Not Cancer Driver No 1 hippie 156 563 78 78 0
ANKRD13D ANKRD13D Q6ZTN6 Ankyrin repeat domain-containing protein 13D chr11 Not Cancer Driver No 3 intact, hippie, biogrid 67 286 24 24 0
AP3B1 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 Not Cancer Driver No 1 hippie, biogrid 126 316 31 31 1
ARL10 ARL10 Q8N8L6 ADP-ribosylation factor-like protein 10 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 19 19 0 0 0
ARMCX3_ENST00000537169 ARMCX3 Q9UH62 Armadillo repeat-containing X-linked protein 3 chrX Not Cancer Driver No 1 hippie, biogrid 39 77 7 7 0
ATP2B4_ENST00000341360 ATP2B4 P23634-2 Isoform XA of Plasma membrane calcium-transporting ATPase 4 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 145 219 21 21 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 Census, Compendium Yes 3 hippie, biogrid 66 21 0 0 8
C1orf112_ENST00000359326 C1orf112 Q9NSG2 Uncharacterized protein C1orf112 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 100 26 2 2 0
C2CD5_ENST00000333957 C2CD5 Q86YS7 C2 domain-containing protein 5 chr12 Not Cancer Driver No 3 intact, hippie, biogrid 136 250 40 40 0
CAND2 CAND2 O75155 Cullin-associated NEDD8-dissociated protein 2 chr3 Not Cancer Driver No 3 intact, hippie, biogrid 133 96 16 16 0
CCDC33_ENST00000558821 CCDC33 Q8N5R6-4 Isoform 4 of Coiled-coil domain-containing protein 33 chr15 Not Cancer Driver No 1 hippie 60 288 51 51 0
CDA CDA P32320 Cytidine deaminase chr1 Not Cancer Driver No 1 hippie 21 8 0 0 0
CIP2A CIP2A Q8TCG1 Protein CIP2A chr3 Not Cancer Driver No 1 hippie 118 240 31 31 0
CMTM4 CMTM4 Q8IZR5 CKLF-like MARVEL transmembrane domain-containing protein 4 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 19 30 1 1 0
CRELD1_ENST00000383811 CRELD1 Q96HD1 Protein disulfide isomerase CRELD1 chr3 Not Cancer Driver No 1 hippie, biogrid 45 44 7 7 4
CWC22 CWC22 Q9HCG8 Pre-mRNA-splicing factor CWC22 homolog chr2 Not Cancer Driver No 3 intact, hippie, biogrid 104 494 56 56 0
CYP51A1 CYP51A1 Q16850 Lanosterol 14-alpha demethylase chr7 Not Cancer Driver No 1 hippie, biogrid 49 7 2 2 0
DHRS7_ENST00000557185 DHRS7 Q9Y394 Dehydrogenase/reductase SDR family member 7 chr14 Not Cancer Driver No 3 intact, hippie, biogrid 37 10 0 0 0
DIP2A DIP2A Q14689 Disco-interacting protein 2 homolog A chr21 Not Cancer Driver No 3 intact, hippie, biogrid 204 396 53 53 0
DOCK7_ENST00000635253 DOCK7 Q96N67 Dedicator of cytokinesis protein 7 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 262 454 53 53 0
DYM DYM Q7RTS9 Dymeclin chr18 Not Cancer Driver No 1 hippie, biogrid 78 21 0 0 3
ECD_ENST00000372979 ECD O95905 Protein ecdysoneless homolog chr10 Not Cancer Driver No 1 hippie, biogrid 68 254 26 26 0
EFEMP2 EFEMP2 O95967 EGF-containing fibulin-like extracellular matrix protein 2 chr11 Not Cancer Driver No 1 hippie 67 41 4 4 8
EIF2B1 EIF2B1 Q14232 Translation initiation factor eIF-2B subunit alpha chr12 Not Cancer Driver No 3 hippie, biogrid 33 0 0 0 2
EIF2B2 EIF2B2 P49770 Translation initiation factor eIF-2B subunit beta chr14 Not Cancer Driver No 3 hippie, biogrid 40 83 11 11 9
EIF2B3 EIF2B3 Q9NR50 Translation initiation factor eIF-2B subunit gamma chr1 Not Cancer Driver No 3 hippie, biogrid 54 28 9 9 5
EIF2B4_ENST00000347454 EIF2B4 Q9UI10 Translation initiation factor eIF-2B subunit delta chr2 Not Cancer Driver No 3 intact, hippie, biogrid 57 212 29 29 7
EIF2B5 EIF2B5 Q13144 Translation initiation factor eIF-2B subunit epsilon chr3 Not Cancer Driver No 3 intact, hippie, biogrid 76 179 16 16 29
EPHX1_ENST00000366837 EPHX1 P07099 Epoxide hydrolase 1 chr1 Not Cancer Driver No 2 intact, hippie, biogrid 75 7 3 3 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 Census, Compendium Yes 3 intact, hippie, biogrid 275 314 41 41 1
EVI5L_ENST00000270530 EVI5L Q96CN4 EVI5-like protein chr19 Not Cancer Driver No 3 hippie, biogrid 70 381 27 27 0
EXOC2 EXOC2 Q96KP1 Exocyst complex component 2 chr6 Not Cancer Driver No 1 hippie, biogrid 105 134 18 18 0
FAM189B FAM189B P81408 Protein FAM189B chr1 Not Cancer Driver No 1 hippie, biogrid 56 302 21 21 0
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 1 hippie, biogrid 176 181 14 14 3
FARP2 FARP2 O94887 FERM, ARHGEF and pleckstrin domain-containing protein 2 chr2 Not Cancer Driver No 3 intact, hippie, biogrid 133 250 39 39 0
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 Census, Compendium Yes 3 intact, hippie, biogrid 253 259 41 41 13
GEMIN4 GEMIN4 P57678 Gem-associated protein 4 chr17 Not Cancer Driver No 1 hippie, biogrid 101 24 1 1 0
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 Not Cancer Driver No 1 hippie 20 52 11 11 0
HEATR3 HEATR3 Q7Z4Q2 HEAT repeat-containing protein 3 chr16 Not Cancer Driver No 3 intact, hippie, biogrid 73 134 10 10 0
HOOK2 HOOK2 Q96ED9 Protein Hook homolog 2 chr19 Not Cancer Driver No 3 intact, hippie, biogrid 94 487 62 62 0
INCA1_ENST00000576820 INCA1 Q0VD86 Protein INCA1 chr17 Not Cancer Driver No 1 hippie 18 195 14 14 0
IPO11_ENST00000325324 IPO11 Q9UI26 Importin-11 chr5 Not Cancer Driver No 1 hippie, biogrid 82 66 4 4 0
IPO7 IPO7 O95373 Importin-7 chr11 Not Cancer Driver No 3 hippie, biogrid 138 202 30 30 0
IPO8 IPO8 O15397 Importin-8 chr12 Not Cancer Driver No 3 intact, hippie, biogrid 130 111 13 13 0
IPO9 IPO9 Q96P70 Importin-9 chr1 Not Cancer Driver No 3 hippie, biogrid 145 102 22 22 0
KRT31 KRT31 Q15323 Keratin, type I cuticular Ha1 chr17 Not Cancer Driver No 1 hippie 116 64 16 16 0
KRT38 KRT38 O76015 Keratin, type I cuticular Ha8 chr17 Not Cancer Driver No 1 hippie 89 52 15 15 0
KRT40_ENST00000398486 KRT40 Q6A162 Keratin, type I cytoskeletal 40 chr17 Not Cancer Driver No 1 hippie 70 6 1 1 0
KRTAP10-3 KRTAP10-3 P60369 Keratin-associated protein 10-3 chr21 Not Cancer Driver No 1 hippie 30 0 0 0 0
KRTAP10-7 KRTAP10-7 P60409 Keratin-associated protein 10-7 chr21 Not Cancer Driver No 1 hippie 70 0 0 0 0
KRTAP10-8 KRTAP10-8 P60410 Keratin-associated protein 10-8 chr21 Not Cancer Driver No 1 hippie 51 0 0 0 0
KRTAP10-9 KRTAP10-9 P60411 Keratin-associated protein 10-9 chr21 Not Cancer Driver No 1 hippie 49 1 0 0 0
KTN1 KTN1 Q86UP2 Kinectin chr14 Census Yes 1 hippie, biogrid 138 964 102 102 0
LGALS1 LGALS1 P09382 Galectin-1 chr22 Not Cancer Driver No 1 hippie, biogrid 16 0 0 0 0
LMBR1 LMBR1 Q8WVP7 Limb region 1 protein homolog chr7 Not Cancer Driver No 1 hippie, biogrid 56 19 1 1 0
LRIG3 LRIG3 Q6UXM1 Leucine-rich repeats and immunoglobulin-like domains protein 3 chr12 Census, Compendium Yes 1 hippie, biogrid 143 230 31 31 0
LSR_ENST00000361790 LSR Q86X29 Lipolysis-stimulated lipoprotein receptor chr19 Not Cancer Driver No 1 hippie, biogrid 89 330 42 42 0
MAP4K4_ENST00000347699 MAP4K4 O95819 Mitogen-activated protein kinase kinase kinase kinase 4 chr2 Not Cancer Driver No 1 hippie, biogrid 143 649 55 55 0
MEOX2 MEOX2 P50222 Homeobox protein MOX-2 chr7 Not Cancer Driver No 1 hippie 70 274 63 63 0
MFAP3 MFAP3 P55082 Microfibril-associated glycoprotein 3 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 33 94 8 8 0
MGAT5B_ENST00000569840 MGAT5B Q3V5L5 Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B chr17 Not Cancer Driver No 1 hippie 148 79 18 18 0
MIGA1_ENST00000370791 MIGA1 Q8NAN2 Mitoguardin 1 chr1 Not Cancer Driver No 2 intact, hippie 83 34 6 6 0
MKLN1 MKLN1 Q9UL63 Muskelin chr7 Not Cancer Driver No 1 hippie 85 91 13 13 0
MYADM MYADM Q96S97 Myeloid-associated differentiation marker chr19 Not Cancer Driver No 3 intact, hippie, biogrid 73 0 0 0 0
NOP9 NOP9 Q86U38 Nucleolar protein 9 chr14 Not Cancer Driver No 2 intact, hippie, biogrid 53 166 14 14 0
NOTCH2NLA NOTCH2NLA Q7Z3S9 Notch homolog 2 N-terminal-like protein A chr1 Not Cancer Driver No 2 intact, hippie 68 17 2 2 0
NUS1 NUS1 Q96E22 Dehydrodolichyl diphosphate synthase complex subunit NUS1 chr6 Not Cancer Driver No 1 intact, hippie, biogrid 21 13 0 0 1
OSBPL8 OSBPL8 Q9BZF1 Oxysterol-binding protein-related protein 8 chr12 Not Cancer Driver No 3 intact, hippie, biogrid 105 401 37 37 0
PBXIP1 PBXIP1 Q96AQ6 Pre-B-cell leukemia transcription factor-interacting protein 1 chr1 Not Cancer Driver No 3 hippie, biogrid 100 605 86 86 0
PEX19 PEX19 P40855 Peroxisomal biogenesis factor 19 chr1 Not Cancer Driver No 1 hippie, biogrid 41 266 38 38 0
PHLDB3 PHLDB3 Q6NSJ2 Pleckstrin homology-like domain family B member 3 chr19 Not Cancer Driver No 1 hippie, biogrid 74 462 50 50 0
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 Census, Compendium Yes 3 intact, hippie, biogrid 150 42 4 4 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 Census, Compendium Yes 1 hippie, biogrid 154 268 61 61 2
PIK3R2_ENST00000617130 PIK3R2 O00459 Phosphatidylinositol 3-kinase regulatory subunit beta chr19 Not Cancer Driver No 3 intact, hippie, biogrid 96 418 47 47 3
PKN3 PKN3 Q6P5Z2 Serine/threonine-protein kinase N3 chr9 Not Cancer Driver No 3 hippie, biogrid 99 392 49 49 0
PKP2 PKP2 Q99959 Plakophilin-2 chr12 Not Cancer Driver No 3 intact, hippie, biogrid 176 434 98 98 8
PKP4 PKP4 Q99569 Plakophilin-4 chr2 Not Cancer Driver No 3 hippie, biogrid 172 756 119 119 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 Not Cancer Driver No 3 intact, hippie, biogrid 313 481 104 104 0
PLD2 PLD2 O14939 Phospholipase D2 chr17 Not Cancer Driver No 1 hippie, biogrid 107 97 8 8 0
PLEKHG4 PLEKHG4 Q58EX7 Puratrophin-1 chr16 Not Cancer Driver No 3 intact, hippie, biogrid 132 295 35 35 0
PLEKHH3 PLEKHH3 Q7Z736 Pleckstrin homology domain-containing family H member 3 chr17 Not Cancer Driver No 3 intact, hippie, biogrid 85 356 43 43 0
PNN PNN Q9H307 Pinin chr14 Not Cancer Driver No 3 hippie, biogrid 94 700 90 90 0
PPP1R15B PPP1R15B Q5SWA1 Protein phosphatase 1 regulatory subunit 15B chr1 Not Cancer Driver No 3 intact, hippie, biogrid 72 415 45 45 1
PTGER1 PTGER1 P34995 Prostaglandin E2 receptor EP1 subtype chr19 Not Cancer Driver No 1 hippie 7 26 1 1 0
PTPRF PTPRF P10586 Receptor-type tyrosine-protein phosphatase F chr1 Not Cancer Driver No 1 hippie, biogrid 268 696 96 96 0
RAB18_ENST00000356940 RAB18 Q9NP72 Ras-related protein Rab-18 chr10 Not Cancer Driver No 1 hippie, biogrid 19 18 2 2 1
REL REL Q04864 Proto-oncogene c-Rel chr2 Census Yes 1 hippie 68 363 43 43 0
RETSAT RETSAT Q6NUM9 All-trans-retinol 13,14-reductase chr2 Not Cancer Driver No 1 hippie, biogrid 98 25 5 5 0
RGS17 RGS17 Q9UGC6 Regulator of G-protein signaling 17 chr6 Not Cancer Driver No 1 hippie 45 48 11 11 0
RGS20 RGS20 O76081 Regulator of G-protein signaling 20 chr8 Not Cancer Driver No 1 hippie 59 194 36 36 0
RHBDF2 RHBDF2 Q6PJF5 Inactive rhomboid protein 2 chr17 Not Cancer Driver No 3 intact, hippie, biogrid 93 284 36 36 2
RNPS1_ENST00000301730 RNPS1 Q15287 RNA-binding protein with serine-rich domain 1 chr16 Not Cancer Driver No 2 intact, hippie, biogrid 30 305 30 30 0
SAAL1 SAAL1 Q96ER3 Protein SAAL1 chr11 Not Cancer Driver No 3 hippie, biogrid 46 75 11 11 0
SLC39A1_ENST00000310483 SLC39A1 Q9NY26 Zinc transporter ZIP1 chr1 Not Cancer Driver No 3 hippie, biogrid 38 22 0 0 0
SLC9A1 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 Not Cancer Driver No 3 hippie, biogrid 89 251 29 29 1
SMYD3 SMYD3 Q9H7B4 Histone-lysine N-methyltransferase SMYD3 chr1 Not Cancer Driver No 1 hippie, biogrid 59 2 0 0 0
SP6_ENST00000342234 SP6 Q3SY56 Transcription factor Sp6 chr17 Not Cancer Driver No 1 hippie, biogrid 55 296 39 39 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 Not Cancer Driver No 1 hippie 46 169 29 29 1
ST7 ST7 Q9NRC1 Suppressor of tumorigenicity 7 protein chr7 Not Cancer Driver No 1 hippie, biogrid 62 64 5 5 0
STAG1 STAG1 Q8WVM7 Cohesin subunit SA-1 chr3 Census Yes 1 hippie, biogrid 226 391 66 66 8
TBC1D15 TBC1D15 Q8TC07 TBC1 domain family member 15 chr12 Not Cancer Driver No 1 hippie, biogrid 90 135 23 23 0
TCF4_ENST00000564999 TCF4 P15884 Transcription factor 4 chr18 Compendium Yes 1 hippie 141 662 136 136 13
TMED8 TMED8 Q6PL24 Protein TMED8 chr14 Not Cancer Driver No 3 intact, hippie, biogrid 43 214 26 26 0
TMEM94_ENST00000314256 TMEM94 Q12767 Transmembrane protein 94 chr17 Not Cancer Driver No 2 intact, hippie 146 225 29 29 0
TNPO2 TNPO2 O14787 Transportin-2 chr19 Not Cancer Driver No 1 hippie, biogrid 99 76 10 10 0
TNPO3 TNPO3 Q9Y5L0 Transportin-3 chr7 Not Cancer Driver No 3 intact, hippie, biogrid 122 12 1 1 1
TRIM42 TRIM42 Q8IWZ5 Tripartite motif-containing protein 42 chr3 Not Cancer Driver No 1 hippie 180 67 14 14 0
TUBGCP2_ENST00000368563 TUBGCP2 Q9BSJ2 Gamma-tubulin complex component 2 chr10 Not Cancer Driver No 3 intact, hippie, biogrid 124 93 16 16 0
TYW1B TYW1B Q6NUM6 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B chr7 Not Cancer Driver No 3 intact, hippie, biogrid 108 161 28 28 0
UBTF UBTF P17480 Nucleolar transcription factor 1 chr17 Not Cancer Driver No 3 intact, hippie, biogrid 100 567 77 77 1
USP46 USP46 P62068 Ubiquitin carboxyl-terminal hydrolase 46 chr4 Not Cancer Driver No 1 hippie, biogrid 48 28 4 4 0
VANGL2 VANGL2 Q9ULK5 Vang-like protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 122 150 37 37 3
VPS8 VPS8 Q8N3P4 Vacuolar protein sorting-associated protein 8 homolog chr3 Not Cancer Driver No 2 intact, hippie, biogrid 184 186 30 30 0
XPO4 XPO4 Q9C0E2 Exportin-4 chr13 Not Cancer Driver No 3 intact, hippie, biogrid 124 66 5 5 0
ZC3H18_ENST00000301011 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 3 hippie, biogrid 139 929 134 134 0