Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AAK1 | AAK1 | Q2M2I8 | AP2-associated protein kinase 1 | chr2 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 109 | 654 | 70 | 70 | 0 |
ABCE1 | ABCE1 | P61221 | ATP-binding cassette sub-family E member 1 | chr4 | Not Cancer Driver | No | 1 | hippie | 74 | 36 | 6 | 6 | 0 |
ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | Census, Compendium | Yes | 1 | hippie | 139 | 604 | 73 | 73 | 2 |
ACBD5_ENST00000375888 | ACBD5 | Q5T8D3 | Acyl-CoA-binding domain-containing protein 5 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 65 | 330 | 45 | 45 | 0 |
ACO2 | ACO2 | Q99798 | Aconitate hydratase, mitochondrial | chr22 | Not Cancer Driver | No | 1 | hippie | 94 | 172 | 19 | 19 | 5 |
ADRM1 | ADRM1 | Q16186 | Proteasomal ubiquitin receptor ADRM1 | chr20 | Not Cancer Driver | No | 4 | hippie, biogrid | 49 | 296 | 40 | 40 | 0 |
AGRN | AGRN | O00468 | Agrin | chr1 | Not Cancer Driver | No | 1 | hippie | 188 | 490 | 40 | 40 | 5 |
AHCYL1 | AHCYL1 | O43865 | S-adenosylhomocysteine hydrolase-like protein 1 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 108 | 10 | 10 | 0 |
AHCYL2 | AHCYL2 | Q96HN2 | Adenosylhomocysteinase 3 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 76 | 208 | 23 | 23 | 0 |
AHR | AHR | P35869 | Aryl hydrocarbon receptor | chr7 | Not Cancer Driver | No | 1 | hippie | 129 | 351 | 75 | 75 | 0 |
AIFM1 | AIFM1 | O95831 | Apoptosis-inducing factor 1, mitochondrial | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 88 | 166 | 22 | 22 | 11 |
AIMP2 | AIMP2 | Q13155 | Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 61 | 8 | 8 | 0 |
ALB | ALB | P02768 | Albumin | chr4 | Compendium | Yes | 1 | hippie | 162 | 6 | 0 | 0 | 3 |
ALDOA_ENST00000643777 | ALDOA | P04075 | Fructose-bisphosphate aldolase A | chr16 | Not Cancer Driver | No | 1 | hippie | 47 | 65 | 9 | 9 | 3 |
ANKIB1 | ANKIB1 | Q9P2G1 | Ankyrin repeat and IBR domain-containing protein 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 141 | 577 | 78 | 78 | 0 |
ANKRD13A | ANKRD13A | Q8IZ07 | Ankyrin repeat domain-containing protein 13A | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 54 | 167 | 16 | 16 | 0 |
ANKRD13B | ANKRD13B | Q86YJ7 | Ankyrin repeat domain-containing protein 13B | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 290 | 18 | 18 | 0 |
AP2B1_ENST00000621914 | AP2B1 | P63010 | AP-2 complex subunit beta | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 85 | 95 | 12 | 12 | 0 |
APC | APC | P25054 | Adenomatous polyposis coli protein | chr5 | Census, Compendium | Yes | 1 | hippie | 412 | 2406 | 345 | 345 | 22 |
APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | Not Cancer Driver | No | 1 | hippie | 128 | 418 | 71 | 71 | 17 |
AQP4 | AQP4 | P55087 | Aquaporin-4 | chr18 | Not Cancer Driver | No | 1 | hippie | 50 | 30 | 9 | 9 | 0 |
ARL2 | ARL2 | P36404 | ADP-ribosylation factor-like protein 2 | chr11 | Not Cancer Driver | No | 1 | biogrid | 19 | 0 | 0 | 0 | 1 |
ATG16L1 | ATG16L1 | Q676U5 | Autophagy-related protein 16-1 | chr2 | Not Cancer Driver | No | 1 | hippie | 79 | 239 | 25 | 25 | 1 |
ATP1A3_ENST00000302102 | ATP1A3 | P13637 | Sodium/potassium-transporting ATPase subunit alpha-3 | chr19 | Not Cancer Driver | No | 1 | hippie | 200 | 115 | 29 | 29 | 31 |
ATP5F1A_ENST00000282050 | ATP5F1A | P25705 | ATP synthase subunit alpha, mitochondrial | chr18 | Not Cancer Driver | No | 1 | hippie | 66 | 23 | 5 | 5 | 2 |
ATP5F1B | ATP5F1B | P06576 | ATP synthase subunit beta, mitochondrial | chr12 | Not Cancer Driver | No | 1 | hippie | 60 | 85 | 8 | 8 | 0 |
ATXN3 | ATXN3 | P54252 | Ataxin-3 | chr14 | Not Cancer Driver | No | 1 | hippie | 46 | 181 | 24 | 24 | 0 |
BAG1 | BAG1 | Q99933 | BAG family molecular chaperone regulator 1 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 29 | 195 | 9 | 9 | 0 |
BAG6 | BAG6 | P46379 | Large proline-rich protein BAG6 | chr6 | Not Cancer Driver | No | 1 | hippie | 98 | 861 | 79 | 79 | 0 |
BAP1 | BAP1 | Q92560 | Ubiquitin carboxyl-terminal hydrolase BAP1 | chr3 | Census, Compendium | Yes | 1 | intact, hippie | 141 | 418 | 59 | 59 | 0 |
BCAP31_ENST00000345046 | BCAP31 | P51572 | B-cell receptor-associated protein 31 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 37 | 104 | 14 | 14 | 0 |
BCAR1_ENST00000162330 | BCAR1 | P56945 | Breast cancer anti-estrogen resistance protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie | 108 | 677 | 75 | 75 | 0 |
BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | Census, Compendium | Yes | 1 | hippie | 77 | 98 | 16 | 16 | 0 |
BRCA1_ENST00000357654 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | Census, Compendium | Yes | 1 | hippie | 224 | 1458 | 174 | 174 | 35 |
BRD4 | BRD4 | O60885 | Bromodomain-containing protein 4 | chr19 | Census, Compendium | Yes | 1 | hippie | 193 | 1182 | 172 | 172 | 0 |
BTRC | BTRC | Q9Y297 | F-box/WD repeat-containing protein 1A | chr10 | Not Cancer Driver | No | 1 | hippie | 80 | 45 | 4 | 4 | 0 |
C3orf62 | C3orf62 | Q6ZUJ4 | Uncharacterized protein C3orf62 | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 31 | 152 | 16 | 16 | 0 |
CAD | CAD | P27708 | CAD protein | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 287 | 368 | 52 | 52 | 1 |
CAPZA2 | CAPZA2 | P47755 | F-actin-capping protein subunit alpha-2 | chr7 | Not Cancer Driver | No | 1 | hippie | 37 | 19 | 0 | 0 | 0 |
CARS2 | CARS2 | Q9HA77 | Probable cysteine--tRNA ligase, mitochondrial | chr13 | Not Cancer Driver | No | 1 | biogrid | 51 | 87 | 8 | 8 | 1 |
CCAR1 | CCAR1 | Q8IX12 | Cell division cycle and apoptosis regulator protein 1 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 145 | 771 | 76 | 76 | 0 |
CCDC74A | CCDC74A | Q96AQ1 | Coiled-coil domain-containing protein 74A | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 90 | 351 | 84 | 84 | 0 |
CCDC74B | CCDC74B | Q96LY2 | Coiled-coil domain-containing protein 74B | chr2 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 74 | 339 | 63 | 63 | 0 |
CCDC92 | CCDC92 | Q53HC0 | Coiled-coil domain-containing protein 92 | chr12 | Not Cancer Driver | No | 3 | hippie, biogrid | 60 | 299 | 49 | 49 | 0 |
CCNA2_ENST00000618014 | CCNA2 | P20248 | Cyclin-A2 | chr4 | Not Cancer Driver | No | 1 | hippie | 45 | 186 | 19 | 19 | 0 |
CCNB1 | CCNB1 | P14635 | G2/mitotic-specific cyclin-B1 | chr5 | Not Cancer Driver | No | 1 | hippie | 49 | 145 | 14 | 14 | 0 |
CCNF | CCNF | P41002 | Cyclin-F | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 106 | 221 | 23 | 23 | 3 |
CDK9 | CDK9 | P50750 | Cyclin-dependent kinase 9 | chr9 | Not Cancer Driver | No | 1 | hippie | 50 | 34 | 2 | 2 | 0 |
CENPP | CENPP | Q6IPU0 | Centromere protein P | chr9 | Not Cancer Driver | No | 1 | biogrid | 30 | 40 | 4 | 4 | 0 |
CFTR | CFTR | P13569 | Cystic fibrosis transmembrane conductance regulator | chr7 | Not Cancer Driver | No | 1 | hippie | 287 | 145 | 18 | 18 | 151 |
CKM | CKM | P06732 | Creatine kinase M-type | chr19 | Not Cancer Driver | No | 1 | hippie | 58 | 118 | 19 | 19 | 0 |
CKMT2_ENST00000437669 | CKMT2 | P17540 | Creatine kinase S-type, mitochondrial | chr5 | Not Cancer Driver | No | 1 | hippie | 70 | 68 | 12 | 12 | 0 |
COPS2_ENST00000388901 | COPS2 | P61201 | COP9 signalosome complex subunit 2 | chr15 | Not Cancer Driver | No | 1 | hippie | 59 | 59 | 9 | 9 | 0 |
COPS7A_ENST00000534947 | COPS7A | Q9UBW8 | COP9 signalosome complex subunit 7a | chr12 | Not Cancer Driver | No | 1 | hippie | 32 | 74 | 10 | 10 | 0 |
CRYAB_ENST00000616970 | CRYAB | P02511 | Alpha-crystallin B chain | chr11 | Not Cancer Driver | No | 1 | hippie | 22 | 59 | 11 | 11 | 4 |
CTNNB1_ENST00000643977 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | Census, Compendium | Yes | 2 | hippie, biogrid | 415 | 288 | 301 | 301 | 14 |
CUL1_ENST00000602748 | CUL1 | Q13616 | Cullin-1 | chr7 | Not Cancer Driver | No | 1 | hippie | 151 | 65 | 9 | 9 | 0 |
CUL2_ENST00000374748 | CUL2 | Q13617 | Cullin-2 | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 87 | 66 | 3 | 3 | 0 |
CUL7_ENST00000265348 | CUL7 | Q14999 | Cullin-7 | chr6 | Not Cancer Driver | No | 1 | hippie | 188 | 372 | 41 | 41 | 3 |
CWC22 | CWC22 | Q9HCG8 | Pre-mRNA-splicing factor CWC22 homolog | chr2 | Not Cancer Driver | No | 1 | biogrid | 104 | 494 | 56 | 56 | 0 |
CYLD | CYLD | Q9NQC7 | Ubiquitin carboxyl-terminal hydrolase CYLD | chr16 | Census, Compendium | Yes | 1 | hippie | 116 | 213 | 31 | 31 | 3 |
CYP2C9 | CYP2C9 | P11712 | Cytochrome P450 2C9 | chr10 | Not Cancer Driver | No | 1 | hippie, biogrid | 122 | 36 | 14 | 14 | 0 |
DCLRE1B | DCLRE1B | Q9H816 | 5' exonuclease Apollo | chr1 | Not Cancer Driver | No | 1 | intact, hippie | 65 | 127 | 17 | 17 | 0 |
DCTN2_ENST00000548249 | DCTN2 | Q13561 | Dynactin subunit 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 46 | 253 | 32 | 32 | 0 |
DDRGK1 | DDRGK1 | Q96HY6 | DDRGK domain-containing protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 34 | 181 | 23 | 23 | 0 |
DESI1 | DESI1 | Q6ICB0 | Desumoylating isopeptidase 1 | chr22 | Not Cancer Driver | No | 1 | hippie | 23 | 34 | 6 | 6 | 0 |
DHFR2_ENST00000314636 | DHFR2 | Q86XF0 | Dihydrofolate reductase 2, mitochondrial | chr3 | Not Cancer Driver | No | 1 | hippie | 25 | 20 | 0 | 0 | 0 |
DIO2_ENST00000557010 | DIO2 | Q92813 | Type II iodothyronine deiodinase | chr14 | Not Cancer Driver | No | 1 | hippie | 73 | 44 | 4 | 4 | 0 |
DIRAS3_ENST00000646789 | DIRAS3 | O95661 | GTP-binding protein Di-Ras3 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 21 | 3 | 3 | 0 |
DLD | DLD | P09622 | Dihydrolipoyl dehydrogenase, mitochondrial | chr7 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 67 | 17 | 0 | 0 | 10 |
ECPAS_ENST00000338205 | ECPAS | Q5VYK3 | Proteasome adapter and scaffold protein ECM29 | chr9 | Not Cancer Driver | No | 1 | hippie | 176 | 240 | 22 | 22 | 0 |
ECT2 | ECT2 | Q9H8V3 | Protein ECT2 | chr3 | Not Cancer Driver | No | 1 | hippie | 104 | 284 | 33 | 33 | 0 |
EEF1G | EEF1G | P26641 | Elongation factor 1-gamma | chr11 | Not Cancer Driver | No | 1 | biogrid | 44 | 66 | 5 | 5 | 0 |
EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | Census, Compendium | Yes | 1 | hippie | 444 | 223 | 35 | 35 | 1 |
EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 13 | 0 | 0 | 0 |
EIF3C | EIF3C | Q99613 | Eukaryotic translation initiation factor 3 subunit C | chr16 | Not Cancer Driver | No | 1 | biogrid | 15 | 391 | 12 | 12 | 0 |
EIF3D | EIF3D | O15371 | Eukaryotic translation initiation factor 3 subunit D | chr22 | Not Cancer Driver | No | 1 | biogrid | 63 | 200 | 26 | 26 | 0 |
ELOC | ELOC | Q15369 | Elongin-C | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 22 | 25 | 5 | 5 | 0 |
ELP1 | ELP1 | O95163 | Elongator complex protein 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 143 | 157 | 23 | 23 | 2 |
ELSPBP1 | ELSPBP1 | Q96BH3 | Epididymal sperm-binding protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 54 | 0 | 0 | 0 | 0 |
EPM2A | EPM2A | O95278 | Laforin | chr6 | Not Cancer Driver | No | 1 | hippie | 29 | 46 | 1 | 1 | 19 |
EPN1_ENST00000270460 | EPN1 | Q9Y6I3 | Epsin-1 | chr19 | Not Cancer Driver | No | 1 | hippie | 87 | 493 | 71 | 71 | 0 |
EPS15 | EPS15 | P42566 | Epidermal growth factor receptor substrate 15 | chr1 | Census, Compendium | Yes | 1 | hippie | 106 | 543 | 66 | 66 | 0 |
ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | Not Cancer Driver | No | 1 | intact, hippie | 90 | 92 | 11 | 11 | 1 |
FAM90A1 | FAM90A1 | Q86YD7 | Protein FAM90A1 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 123 | 461 | 121 | 121 | 0 |
FARSA | FARSA | Q9Y285 | Phenylalanine--tRNA ligase alpha subunit | chr19 | Not Cancer Driver | No | 1 | biogrid | 75 | 120 | 25 | 25 | 0 |
FBXO25 | FBXO25 | Q8TCJ0 | F-box only protein 25 | chr8 | Not Cancer Driver | No | 1 | hippie | 33 | 20 | 0 | 0 | 0 |
FBXO6 | FBXO6 | Q9NRD1 | F-box only protein 6 | chr1 | Not Cancer Driver | No | 1 | hippie | 31 | 27 | 3 | 3 | 0 |
FKBP8_ENST00000222308 | FKBP8 | Q14318 | Peptidyl-prolyl cis-trans isomerase FKBP8 | chr19 | Not Cancer Driver | No | 1 | hippie | 71 | 160 | 25 | 25 | 0 |
FLOT1 | FLOT1 | O75955 | Flotillin-1 | chr6 | Not Cancer Driver | No | 1 | hippie | 43 | 122 | 15 | 15 | 0 |
FZR1 | FZR1 | Q9UM11 | Fizzy-related protein homolog | chr19 | Not Cancer Driver | No | 1 | hippie | 74 | 184 | 30 | 30 | 0 |
GFPT1 | GFPT1 | Q06210 | Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 75 | 8 | 8 | 13 |
GGA1 | GGA1 | Q9UJY5 | ADP-ribosylation factor-binding protein GGA1 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 75 | 385 | 33 | 33 | 0 |
GJA1 | GJA1 | P17302 | Gap junction alpha-1 protein | chr6 | Not Cancer Driver | No | 1 | hippie | 86 | 110 | 26 | 26 | 50 |
GJD3 | GJD3 | Q8N144 | Gap junction delta-3 protein | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 5 | 79 | 0 | 0 | 0 |
GNB5 | GNB5 | O14775 | Guanine nucleotide-binding protein subunit beta-5 | chr15 | Not Cancer Driver | No | 1 | hippie | 60 | 16 | 1 | 1 | 1 |
GNL3L_ENST00000360845 | GNL3L | Q9NVN8 | Guanine nucleotide-binding protein-like 3-like protein | chrX | Not Cancer Driver | No | 1 | biogrid | 120 | 242 | 43 | 43 | 0 |
GOLGA2_ENST00000611957 | GOLGA2 | Q08379 | Golgin subfamily A member 2 | chr9 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 115 | 854 | 96 | 96 | 0 |
GOT2 | GOT2 | P00505 | Aspartate aminotransferase, mitochondrial | chr16 | Not Cancer Driver | No | 1 | hippie | 61 | 25 | 3 | 3 | 1 |
GSN | GSN | P06396 | Gelsolin | chr9 | Not Cancer Driver | No | 1 | hippie | 76 | 316 | 28 | 28 | 2 |
HADHA | HADHA | P40939 | Trifunctional enzyme subunit alpha, mitochondrial | chr2 | Not Cancer Driver | No | 1 | hippie | 72 | 19 | 2 | 2 | 5 |
HERC3 | HERC3 | Q15034 | Probable E3 ubiquitin-protein ligase HERC3 | chr4 | Not Cancer Driver | No | 1 | hippie | 112 | 56 | 7 | 7 | 0 |
HEXIM1 | HEXIM1 | O94992 | Protein HEXIM1 | chr17 | Not Cancer Driver | No | 1 | hippie | 40 | 352 | 40 | 40 | 0 |
HIF1AN | HIF1AN | Q9NWT6 | Hypoxia-inducible factor 1-alpha inhibitor | chr10 | Not Cancer Driver | No | 1 | hippie | 37 | 77 | 9 | 9 | 0 |
HLA-B | HLA-B | P01889 | HLA class I histocompatibility antigen, B alpha chain | chr6 | Compendium | Yes | 1 | hippie | 78 | 169 | 34 | 34 | 0 |
HSPA4 | HSPA4 | P34932 | Heat shock 70 kDa protein 4 | chr5 | Not Cancer Driver | No | 1 | hippie | 80 | 351 | 24 | 24 | 0 |
HSPA8_ENST00000532636 | HSPA8 | P11142 | Heat shock cognate 71 kDa protein | chr11 | Not Cancer Driver | No | 1 | hippie | 149 | 251 | 52 | 52 | 0 |
HTT | HTT | P42858 | Huntingtin | chr4 | Not Cancer Driver | No | 2 | intact, hippie | 336 | 666 | 69 | 69 | 2 |
HUWE1_ENST00000262854 | HUWE1 | Q7Z6Z7 | E3 ubiquitin-protein ligase HUWE1 | chrX | Not Cancer Driver | No | 1 | hippie | 669 | 2091 | 329 | 329 | 21 |
ID1 | ID1 | P41134 | DNA-binding protein inhibitor ID-1 | chr20 | Not Cancer Driver | No | 2 | intact, hippie | 20 | 17 | 6 | 6 | 0 |
IDH3A | IDH3A | P50213 | Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial | chr15 | Not Cancer Driver | No | 1 | hippie | 41 | 47 | 11 | 11 | 0 |
IFITM1_ENST00000528780 | IFITM1 | P13164 | Interferon-induced transmembrane protein 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 19 | 0 | 0 | 0 | 0 |
IFITM3 | IFITM3 | Q01628 | Interferon-induced transmembrane protein 3 | chr11 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 69 | 18 | 5 | 5 | 0 |
IMPDH2 | IMPDH2 | P12268 | Inosine-5'-monophosphate dehydrogenase 2 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 70 | 6 | 1 | 1 | 0 |
INS | INS | P01308 | Insulin | chr11 | Not Cancer Driver | No | 1 | hippie | 15 | 5 | 1 | 1 | 22 |
INSIG2 | INSIG2 | Q9Y5U4 | Insulin-induced gene 2 protein | chr2 | Not Cancer Driver | No | 1 | hippie | 47 | 11 | 3 | 3 | 0 |
INTS5 | INTS5 | Q6P9B9 | Integrator complex subunit 5 | chr11 | Not Cancer Driver | No | 1 | biogrid | 123 | 189 | 22 | 22 | 0 |
ITGA2 | ITGA2 | P17301 | Integrin alpha-2 | chr5 | Not Cancer Driver | No | 1 | hippie | 166 | 26 | 0 | 0 | 0 |
ITGB2_ENST00000355153 | ITGB2 | P05107 | Integrin beta-2 | chr21 | Not Cancer Driver | No | 1 | hippie | 147 | 59 | 9 | 9 | 15 |
JAZF1 | JAZF1 | Q86VZ6 | Juxtaposed with another zinc finger protein 1 | chr7 | Census | Yes | 1 | intact, hippie | 29 | 172 | 21 | 21 | 0 |
JUN | JUN | P05412 | Transcription factor Jun | chr1 | Census | Yes | 1 | hippie | 35 | 281 | 25 | 25 | 0 |
KDELR1 | KDELR1 | P24390 | ER lumen protein-retaining receptor 1 | chr19 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 32 | 0 | 0 | 0 | 0 |
KEAP1_ENST00000393623 | KEAP1 | Q14145 | Kelch-like ECH-associated protein 1 | chr19 | Census, Compendium | Yes | 1 | hippie | 237 | 57 | 12 | 12 | 0 |
KIF14 | KIF14 | Q15058 | Kinesin-like protein KIF14 | chr1 | Not Cancer Driver | No | 1 | hippie | 222 | 774 | 102 | 102 | 2 |
KLF16 | KLF16 | Q9BXK1 | Krueppel-like factor 16 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 13 | 204 | 8 | 8 | 0 |
KLF8 | KLF8 | O95600 | Krueppel-like factor 8 | chrX | Not Cancer Driver | No | 1 | intact, hippie | 71 | 270 | 53 | 53 | 0 |
LAGE3 | LAGE3 | Q14657 | EKC/KEOPS complex subunit LAGE3 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 95 | 8 | 8 | 2 |
LARP7_ENST00000344442 | LARP7 | Q4G0J3 | La-related protein 7 | chr4 | Not Cancer Driver | No | 1 | hippie | 58 | 350 | 44 | 44 | 0 |
LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 519 | 90 | 17 | 17 | 23 |
MAF_ENST00000393350 | MAF | O75444 | Transcription factor Maf | chr16 | Census, Compendium | Yes | 1 | hippie | 39 | 331 | 37 | 37 | 11 |
MAP1LC3A_ENST00000397709 | MAP1LC3A | Q9H492 | Microtubule-associated proteins 1A/1B light chain 3A | chr20 | Not Cancer Driver | No | 1 | hippie | 22 | 24 | 1 | 1 | 0 |
MAP3K1 | MAP3K1 | Q13233 | Mitogen-activated protein kinase kinase kinase 1 | chr5 | Census, Compendium | Yes | 1 | hippie | 184 | 820 | 62 | 62 | 3 |
MAPK6 | MAPK6 | Q16659 | Mitogen-activated protein kinase 6 | chr15 | Not Cancer Driver | No | 1 | hippie | 79 | 165 | 20 | 20 | 0 |
MAPT_ENST00000262410 | MAPT | P10636 | Microtubule-associated protein tau | chr17 | Not Cancer Driver | No | 1 | hippie | 128 | 750 | 126 | 126 | 18 |
MBTPS2 | MBTPS2 | O43462 | Membrane-bound transcription factor site-2 protease | chrX | Not Cancer Driver | No | 1 | biogrid | 63 | 16 | 4 | 4 | 9 |
MB_ENST00000397328 | MB | P02144 | Myoglobin | chr22 | Not Cancer Driver | No | 1 | hippie | 13 | 38 | 4 | 4 | 0 |
MCFD2_ENST00000409973 | MCFD2 | Q8NI22 | Multiple coagulation factor deficiency protein 2 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 90 | 11 | 11 | 4 |
MCM5 | MCM5 | P33992 | DNA replication licensing factor MCM5 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 88 | 109 | 20 | 20 | 1 |
MDC1 | MDC1 | Q14676 | Mediator of DNA damage checkpoint protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 249 | 1829 | 223 | 223 | 0 |
MDH2 | MDH2 | P40926 | Malate dehydrogenase, mitochondrial | chr7 | Not Cancer Driver | No | 1 | hippie | 39 | 8 | 1 | 1 | 3 |
MDM2_ENST00000539479 | MDM2 | Q00987 | E3 ubiquitin-protein ligase Mdm2 | chr12 | Census, Compendium | Yes | 1 | hippie | 56 | 297 | 37 | 37 | 0 |
MED1 | MED1 | Q15648 | Mediator of RNA polymerase II transcription subunit 1 | chr17 | Not Cancer Driver | No | 1 | biogrid | 162 | 1104 | 117 | 117 | 0 |
MED24_ENST00000394128 | MED24 | O75448 | Mediator of RNA polymerase II transcription subunit 24 | chr17 | Not Cancer Driver | No | 1 | biogrid | 101 | 76 | 0 | 0 | 0 |
MEPCE | MEPCE | Q7L2J0 | 7SK snRNA methylphosphate capping enzyme | chr7 | Not Cancer Driver | No | 1 | hippie | 76 | 446 | 42 | 42 | 0 |
MFAP1 | MFAP1 | P55081 | Microfibrillar-associated protein 1 | chr15 | Not Cancer Driver | No | 1 | biogrid | 58 | 377 | 53 | 53 | 0 |
MFN2_ENST00000444836 | MFN2 | O95140 | Mitofusin-2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 80 | 81 | 9 | 9 | 20 |
MKRN1 | MKRN1 | Q9UHC7 | E3 ubiquitin-protein ligase makorin-1 | chr7 | Not Cancer Driver | No | 1 | hippie | 42 | 155 | 16 | 16 | 0 |
MRPL15 | MRPL15 | Q9P015 | 39S ribosomal protein L15, mitochondrial | chr8 | Not Cancer Driver | No | 1 | biogrid | 32 | 81 | 3 | 3 | 0 |
MRPL22 | MRPL22 | Q9NWU5 | 39S ribosomal protein L22, mitochondrial | chr5 | Not Cancer Driver | No | 1 | biogrid | 23 | 28 | 2 | 2 | 0 |
MRPL43_ENST00000318325 | MRPL43 | Q8N983 | 39S ribosomal protein L43, mitochondrial | chr10 | Not Cancer Driver | No | 1 | biogrid | 17 | 66 | 6 | 6 | 0 |
MRPL57 | MRPL57 | Q9BQC6 | Ribosomal protein 63, mitochondrial | chr13 | Not Cancer Driver | No | 1 | biogrid | 11 | 9 | 1 | 1 | 0 |
MSH6 | MSH6 | P52701 | DNA mismatch repair protein Msh6 | chr2 | Census | Yes | 1 | intact, hippie | 154 | 386 | 41 | 41 | 6 |
MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | Census, Compendium | Yes | 1 | hippie | 80 | 299 | 46 | 46 | 0 |
MYH7 | MYH7 | P12883 | Myosin-7 | chr14 | Not Cancer Driver | No | 1 | hippie | 464 | 1107 | 276 | 276 | 200 |
MYOD1 | MYOD1 | P15172 | Myoblast determination protein 1 | chr11 | Census | Yes | 1 | hippie | 45 | 246 | 33 | 33 | 0 |
NAA40 | NAA40 | Q86UY6 | N-alpha-acetyltransferase 40 | chr11 | Not Cancer Driver | No | 1 | hippie | 22 | 30 | 3 | 3 | 0 |
NAP1L1 | NAP1L1 | P55209 | Nucleosome assembly protein 1-like 1 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 47 | 207 | 31 | 31 | 0 |
NCAPD3 | NCAPD3 | P42695 | Condensin-2 complex subunit D3 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 193 | 304 | 42 | 42 | 1 |
NDUFB1_ENST00000605997 | NDUFB1 | O75438 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 | chr14 | Not Cancer Driver | No | 1 | biogrid | 5 | 0 | 0 | 0 | 0 |
NDUFB2_ENST00000247866 | NDUFB2 | O95178 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial | chr7 | Not Cancer Driver | No | 1 | biogrid | 13 | 26 | 3 | 3 | 0 |
NEDD4 | NEDD4 | P46934 | E3 ubiquitin-protein ligase NEDD4 | chr15 | Not Cancer Driver | No | 1 | hippie | 150 | 711 | 79 | 79 | 0 |
NEDD4L | NEDD4L | Q96PU5 | E3 ubiquitin-protein ligase NEDD4-like | chr18 | Not Cancer Driver | No | 1 | hippie | 126 | 463 | 60 | 60 | 4 |
NEDD8 | NEDD8 | Q15843 | NEDD8 | chr14 | Not Cancer Driver | No | 1 | hippie | 10 | 36 | 5 | 5 | 0 |
NEMF | NEMF | O60524 | Ribosome quality control complex subunit NEMF | chr14 | Not Cancer Driver | No | 1 | biogrid | 109 | 517 | 61 | 61 | 0 |
NEURL4 | NEURL4 | Q96JN8 | Neuralized-like protein 4 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 217 | 751 | 119 | 119 | 0 |
NFX1 | NFX1 | Q12986 | Transcriptional repressor NF-X1 | chr9 | Not Cancer Driver | No | 1 | hippie | 121 | 491 | 46 | 46 | 0 |
NOS2 | NOS2 | P35228 | Nitric oxide synthase, inducible | chr17 | Not Cancer Driver | No | 1 | hippie | 207 | 201 | 33 | 33 | 0 |
NPM1 | NPM1 | P06748 | Nucleophosmin | chr5 | Census, Compendium | Yes | 1 | hippie | 29 | 249 | 22 | 22 | 0 |
NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | Census, Compendium | Yes | 1 | hippie | 168 | 57 | 8 | 8 | 25 |
NUB1_ENST00000470229 | NUB1 | Q9Y5A7 | NEDD8 ultimate buster 1 | chr7 | Not Cancer Driver | No | 1 | hippie | 52 | 180 | 15 | 15 | 0 |
NUBP2 | NUBP2 | Q9Y5Y2 | Cytosolic Fe-S cluster assembly factor NUBP2 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 14 | 0 | 0 | 0 |
NUPR1_ENST00000324873 | NUPR1 | O60356 | Nuclear protein 1 | chr16 | Not Cancer Driver | No | 2 | intact, hippie | 10 | 82 | 10 | 10 | 0 |
OGT | OGT | O15294 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | chrX | Not Cancer Driver | No | 1 | hippie | 156 | 89 | 16 | 16 | 2 |
PAAF1 | PAAF1 | Q9BRP4 | Proteasomal ATPase-associated factor 1 | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 23 | 3 | 3 | 0 |
PAGE4_ENST00000376141 | PAGE4 | O60829 | P antigen family member 4 | chrX | Not Cancer Driver | No | 1 | hippie | 20 | 102 | 20 | 20 | 0 |
PAX3_ENST00000350526 | PAX3 | P23760 | Paired box protein Pax-3 | chr2 | Census | Yes | 1 | hippie | 113 | 391 | 95 | 95 | 28 |
PCNT | PCNT | O95613 | Pericentrin | chr21 | Not Cancer Driver | No | 1 | hippie | 436 | 2474 | 337 | 337 | 0 |
PDIA4 | PDIA4 | P13667 | Protein disulfide-isomerase A4 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 81 | 147 | 22 | 22 | 0 |
PDIA6_ENST00000272227 | PDIA6 | Q15084 | Protein disulfide-isomerase A6 | chr2 | Not Cancer Driver | No | 1 | hippie, biogrid | 55 | 82 | 11 | 11 | 0 |
PELO | PELO | Q9BRX2 | Protein pelota homolog | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 38 | 67 | 10 | 10 | 0 |
PIH1D1 | PIH1D1 | Q9NWS0 | PIH1 domain-containing protein 1 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 30 | 157 | 13 | 13 | 0 |
PIK3C3 | PIK3C3 | Q8NEB9 | Phosphatidylinositol 3-kinase catalytic subunit type 3 | chr18 | Not Cancer Driver | No | 1 | hippie | 127 | 191 | 34 | 34 | 0 |
PLEKHA4 | PLEKHA4 | Q9H4M7 | Pleckstrin homology domain-containing family A member 4 | chr19 | Not Cancer Driver | No | 1 | hippie | 136 | 687 | 128 | 128 | 0 |
POLE | POLE | Q07864 | DNA polymerase epsilon catalytic subunit A | chr12 | Census, Compendium | Yes | 1 | hippie, biogrid | 409 | 239 | 44 | 44 | 3 |
PPIA | PPIA | P62937 | Peptidyl-prolyl cis-trans isomerase A | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 24 | 3 | 3 | 0 |
PPM1D | PPM1D | O15297 | Protein phosphatase 1D | chr17 | Census, Compendium | Yes | 1 | hippie | 54 | 370 | 32 | 32 | 0 |
PPP6C_ENST00000373547 | PPP6C | O00743 | Serine/threonine-protein phosphatase 6 catalytic subunit | chr9 | Census, Compendium | Yes | 1 | hippie | 63 | 0 | 0 | 0 | 0 |
PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | Not Cancer Driver | No | 1 | hippie | 110 | 78 | 15 | 15 | 31 |
PRPS2_ENST00000380668 | PRPS2 | P11908 | Ribose-phosphate pyrophosphokinase 2 | chrX | Not Cancer Driver | No | 1 | hippie | 56 | 4 | 1 | 1 | 0 |
PSMA1_ENST00000396394 | PSMA1 | P25786 | Proteasome subunit alpha type-1 | chr11 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 48 | 51 | 9 | 9 | 0 |
PSMA2 | PSMA2 | P25787 | Proteasome subunit alpha type-2 | chr7 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 20 | 0 | 0 | 0 | 0 |
PSMA3 | PSMA3 | P25788 | Proteasome subunit alpha type-3 | chr14 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 27 | 30 | 5 | 5 | 0 |
PSMA4_ENST00000559082 | PSMA4 | P25789 | Proteasome subunit alpha type-4 | chr15 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 29 | 28 | 9 | 9 | 0 |
PSMA5 | PSMA5 | P28066 | Proteasome subunit alpha type-5 | chr1 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 24 | 23 | 1 | 1 | 0 |
PSMA6 | PSMA6 | P60900 | Proteasome subunit alpha type-6 | chr14 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 37 | 2 | 1 | 1 | 0 |
PSMA7 | PSMA7 | O14818 | Proteasome subunit alpha type-7 | chr20 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 24 | 23 | 1 | 1 | 0 |
PSMA8 | PSMA8 | Q8TAA3 | Proteasome subunit alpha-type 8 | chr18 | Not Cancer Driver | No | 1 | intact | 42 | 15 | 5 | 5 | 0 |
PSMB1 | PSMB1 | P20618 | Proteasome subunit beta type-1 | chr6 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 25 | 14 | 2 | 2 | 0 |
PSMB10 | PSMB10 | P40306 | Proteasome subunit beta type-10 | chr16 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 22 | 36 | 5 | 5 | 0 |
PSMB2 | PSMB2 | P49721 | Proteasome subunit beta type-2 | chr1 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 24 | 0 | 0 | 0 | 0 |
PSMB4 | PSMB4 | P28070 | Proteasome subunit beta type-4 | chr1 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 23 | 18 | 2 | 2 | 0 |
PSMB5 | PSMB5 | P28074 | Proteasome subunit beta type-5 | chr14 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 39 | 9 | 0 | 0 | 0 |
PSMB6 | PSMB6 | P28072 | Proteasome subunit beta type-6 | chr17 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 19 | 22 | 1 | 1 | 0 |
PSMB7 | PSMB7 | Q99436 | Proteasome subunit beta type-7 | chr9 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 25 | 26 | 3 | 3 | 0 |
PSMB8 | PSMB8 | P28062 | Proteasome subunit beta type-8 | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 43 | 62 | 7 | 7 | 3 |
PSMB9 | PSMB9 | P28065 | Proteasome subunit beta type-9 | chr6 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 21 | 17 | 1 | 1 | 1 |
PSMC1 | PSMC1 | P62191 | 26S proteasome regulatory subunit 4 | chr14 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 36 | 165 | 10 | 10 | 0 |
PSMC2_ENST00000292644 | PSMC2 | P35998 | 26S proteasome regulatory subunit 7 | chr7 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 63 | 120 | 13 | 13 | 0 |
PSMC3_ENST00000298852 | PSMC3 | P17980 | 26S proteasome regulatory subunit 6A | chr11 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 55 | 131 | 10 | 10 | 0 |
PSMC4 | PSMC4 | P43686 | 26S proteasome regulatory subunit 6B | chr19 | Not Cancer Driver | No | 4 | hippie, biogrid | 51 | 21 | 3 | 3 | 0 |
PSMC5 | PSMC5 | P62195 | 26S proteasome regulatory subunit 8 | chr17 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 52 | 64 | 6 | 6 | 0 |
PSMC6_ENST00000606149 | PSMC6 | P62333 | 26S proteasome regulatory subunit 10B | chr14 | Not Cancer Driver | No | 6 | intact, hippie, biogrid | 49 | 69 | 8 | 8 | 0 |
PSMD1 | PSMD1 | Q99460 | 26S proteasome non-ATPase regulatory subunit 1 | chr2 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 110 | 201 | 19 | 19 | 0 |
PSMD10 | PSMD10 | O75832 | 26S proteasome non-ATPase regulatory subunit 10 | chrX | Not Cancer Driver | No | 4 | hippie, biogrid | 20 | 53 | 5 | 5 | 0 |
PSMD11_ENST00000457654 | PSMD11 | O00231 | 26S proteasome non-ATPase regulatory subunit 11 | chr17 | Not Cancer Driver | No | 6 | intact, hippie, biogrid | 51 | 0 | 0 | 0 | 0 |
PSMD12 | PSMD12 | O00232 | 26S proteasome non-ATPase regulatory subunit 12 | chr17 | Not Cancer Driver | No | 4 | intact, hippie, biogrid | 48 | 24 | 3 | 3 | 0 |
PSMD13_ENST00000532097 | PSMD13 | Q9UNM6 | 26S proteasome non-ATPase regulatory subunit 13 | chr11 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 30 | 13 | 3 | 3 | 0 |
PSMD14 | PSMD14 | O00487 | 26S proteasome non-ATPase regulatory subunit 14 | chr2 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 23 | 67 | 6 | 6 | 0 |
PSMD2 | PSMD2 | Q13200 | 26S proteasome non-ATPase regulatory subunit 2 | chr3 | Not Cancer Driver | No | 6 | intact, hippie, biogrid | 100 | 135 | 14 | 14 | 0 |
PSMD3 | PSMD3 | O43242 | 26S proteasome non-ATPase regulatory subunit 3 | chr17 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 69 | 152 | 19 | 19 | 0 |
PSMD4_ENST00000368884 | PSMD4 | P55036 | 26S proteasome non-ATPase regulatory subunit 4 | chr1 | Not Cancer Driver | No | 2 | intact, hippie | 43 | 243 | 25 | 25 | 0 |
PSMD5 | PSMD5 | Q16401 | 26S proteasome non-ATPase regulatory subunit 5 | chr9 | Not Cancer Driver | No | 3 | hippie, biogrid | 43 | 2 | 1 | 1 | 0 |
PSMD6_ENST00000295901 | PSMD6 | Q15008 | 26S proteasome non-ATPase regulatory subunit 6 | chr3 | Not Cancer Driver | No | 6 | intact, hippie, biogrid | 33 | 40 | 3 | 3 | 0 |
PSMD7 | PSMD7 | P51665 | 26S proteasome non-ATPase regulatory subunit 7 | chr16 | Not Cancer Driver | No | 7 | intact, hippie, biogrid | 39 | 70 | 4 | 4 | 0 |
PSMD8 | PSMD8 | P48556 | 26S proteasome non-ATPase regulatory subunit 8 | chr19 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 20 | 78 | 2 | 2 | 0 |
PSMD9 | PSMD9 | O00233 | 26S proteasome non-ATPase regulatory subunit 9 | chr12 | Not Cancer Driver | No | 2 | hippie, biogrid | 22 | 173 | 16 | 16 | 0 |
PSME3_ENST00000590720 | PSME3 | P61289 | Proteasome activator complex subunit 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 20 | 25 | 5 | 5 | 0 |
PTEN | PTEN | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | chr10 | Census, Compendium | Yes | 1 | hippie | 505 | 76 | 4 | 4 | 41 |
PTPN2 | PTPN2 | P17706 | Tyrosine-protein phosphatase non-receptor type 2 | chr18 | Not Cancer Driver | No | 1 | intact, hippie | 57 | 120 | 14 | 14 | 0 |
PTPN6_ENST00000318974 | PTPN6 | P29350 | Tyrosine-protein phosphatase non-receptor type 6 | chr12 | Census, Compendium | Yes | 1 | intact, hippie | 73 | 192 | 25 | 25 | 0 |
PTPRA_ENST00000399903 | PTPRA | P18433 | Receptor-type tyrosine-protein phosphatase alpha | chr20 | Not Cancer Driver | No | 1 | hippie | 98 | 210 | 21 | 21 | 0 |
PTPRM_ENST00000332175 | PTPRM | P28827 | Receptor-type tyrosine-protein phosphatase mu | chr18 | Not Cancer Driver | No | 1 | hippie | 256 | 365 | 60 | 60 | 0 |
PXMP2 | PXMP2 | Q9NR77 | Peroxisomal membrane protein 2 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 15 | 0 | 0 | 0 | 0 |
RAD23A | RAD23A | P54725 | UV excision repair protein RAD23 homolog A | chr19 | Not Cancer Driver | No | 7 | intact, hippie | 50 | 283 | 41 | 41 | 0 |
RAD23B | RAD23B | P54727 | UV excision repair protein RAD23 homolog B | chr9 | Not Cancer Driver | No | 2 | hippie, biogrid | 54 | 324 | 41 | 41 | 0 |
RASSF8_ENST00000541490 | RASSF8 | Q8NHQ8 | Ras association domain-containing protein 8 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 47 | 206 | 19 | 19 | 0 |
RBCK1 | RBCK1 | Q9BYM8 | RanBP-type and C3HC4-type zinc finger-containing protein 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 52 | 140 | 14 | 14 | 2 |
RELA | RELA | Q04206 | Transcription factor p65 | chr11 | Compendium | Yes | 1 | hippie | 75 | 400 | 48 | 48 | 0 |
RNF11 | RNF11 | Q9Y3C5 | RING finger protein 11 | chr1 | Not Cancer Driver | No | 1 | hippie | 17 | 76 | 7 | 7 | 0 |
RNF4 | RNF4 | P78317 | E3 ubiquitin-protein ligase RNF4 | chr4 | Not Cancer Driver | No | 1 | hippie | 14 | 117 | 7 | 7 | 0 |
RPA1 | RPA1 | P27694 | Replication protein A 70 kDa DNA-binding subunit | chr17 | Not Cancer Driver | No | 1 | hippie | 51 | 98 | 6 | 6 | 0 |
RPL11 | RPL11 | P62913 | 60S ribosomal protein L11 | chr1 | Not Cancer Driver | No | 1 | biogrid | 27 | 12 | 1 | 1 | 1 |
RPS12 | RPS12 | P25398 | 40S ribosomal protein S12 | chr6 | Not Cancer Driver | No | 1 | hippie | 17 | 0 | 0 | 0 | 0 |
RPS20_ENST00000521262 | RPS20 | P60866 | 40S ribosomal protein S20 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 53 | 8 | 8 | 0 |
RPS6 | RPS6 | P62753 | 40S ribosomal protein S6 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 38 | 150 | 25 | 25 | 0 |
RTF1 | RTF1 | Q92541 | RNA polymerase-associated protein RTF1 homolog | chr15 | Not Cancer Driver | No | 1 | biogrid | 83 | 568 | 67 | 67 | 0 |
S100P | S100P | P25815 | Protein S100-P | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 7 | 3 | 1 | 1 | 0 |
SCHIP1 | SCHIP1 | P0DPB3-4 | Isoform SCHIP1-4 of Schwannomin-interacting protein 1 | chr3 | Not Cancer Driver | No | 1 | intact, hippie | 50 | 202 | 45 | 45 | 0 |
SEM1_ENST00000356686 | SEM1 | Q6ZVN7 | Putative protein SEM1, isoform 2 | chr7 | Not Cancer Driver | No | 1 | hippie | 2 | 52 | 1 | 1 | 0 |
SIAH2 | SIAH2 | O43255 | E3 ubiquitin-protein ligase SIAH2 | chr3 | Not Cancer Driver | No | 1 | hippie | 48 | 68 | 3 | 3 | 0 |
SMURF1 | SMURF1 | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 | chr7 | Not Cancer Driver | No | 1 | hippie | 89 | 256 | 31 | 31 | 0 |
SMYD2 | SMYD2 | Q9NRG4 | N-lysine methyltransferase SMYD2 | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 42 | 12 | 0 | 0 | 0 |
SNAI1 | SNAI1 | O95863 | Zinc finger protein SNAI1 | chr20 | Not Cancer Driver | No | 1 | hippie | 52 | 97 | 11 | 11 | 0 |
SNAPC1 | SNAPC1 | Q16533 | snRNA-activating protein complex subunit 1 | chr14 | Not Cancer Driver | No | 1 | biogrid | 36 | 158 | 16 | 16 | 0 |
SOD1 | SOD1 | P00441 | Superoxide dismutase [Cu-Zn] | chr21 | Not Cancer Driver | No | 1 | hippie | 16 | 93 | 9 | 9 | 79 |
SPRTN | SPRTN | Q9H040 | DNA-dependent metalloprotease SPRTN | chr1 | Not Cancer Driver | No | 1 | hippie | 73 | 252 | 38 | 38 | 1 |
SQSTM1 | SQSTM1 | Q13501 | Sequestosome-1 | chr5 | Not Cancer Driver | No | 1 | hippie | 54 | 267 | 32 | 32 | 30 |
SREBF2 | SREBF2 | Q12772 | Sterol regulatory element-binding protein 2 | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 124 | 357 | 43 | 43 | 0 |
SSBP1_ENST00000484178 | SSBP1 | Q04837 | Single-stranded DNA-binding protein, mitochondrial | chr7 | Not Cancer Driver | No | 1 | biogrid | 27 | 0 | 0 | 0 | 6 |
STK24 | STK24 | Q9Y6E0 | Serine/threonine-protein kinase 24 | chr13 | Not Cancer Driver | No | 1 | hippie | 67 | 118 | 16 | 16 | 0 |
STK25 | STK25 | O00506 | Serine/threonine-protein kinase 25 | chr2 | Not Cancer Driver | No | 1 | hippie | 42 | 170 | 15 | 15 | 0 |
STUB1 | STUB1 | Q9UNE7 | E3 ubiquitin-protein ligase CHIP | chr16 | Not Cancer Driver | No | 2 | hippie, biogrid | 35 | 112 | 14 | 14 | 12 |
SUMO2 | SUMO2 | P61956 | Small ubiquitin-related modifier 2 | chr17 | Not Cancer Driver | No | 1 | hippie | 9 | 69 | 6 | 6 | 0 |
TCF3 | TCF3 | P15923 | Transcription factor E2-alpha | chr19 | Census | Yes | 1 | hippie | 52 | 649 | 52 | 52 | 0 |
TCP11L1_ENST00000432887 | TCP11L1 | Q9NUJ3 | T-complex protein 11-like protein 1 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 59 | 74 | 8 | 8 | 0 |
TERF1 | TERF1 | P54274 | Telomeric repeat-binding factor 1 | chr8 | Not Cancer Driver | No | 1 | hippie | 63 | 220 | 34 | 34 | 0 |
TERF2IP | TERF2IP | Q9NYB0 | Telomeric repeat-binding factor 2-interacting protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 310 | 16 | 16 | 0 |
TGM2 | TGM2 | P21980 | Protein-glutamine gamma-glutamyltransferase 2 | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 123 | 107 | 26 | 26 | 0 |
THBS1 | THBS1 | P07996 | Thrombospondin-1 | chr15 | Not Cancer Driver | No | 1 | hippie | 188 | 320 | 58 | 58 | 0 |
TMEM129_ENST00000536901 | TMEM129 | A0AVI4 | E3 ubiquitin-protein ligase TM129 | chr4 | Not Cancer Driver | No | 1 | hippie | 15 | 8 | 1 | 1 | 0 |
TMEM31 | TMEM31 | Q5JXX7 | Transmembrane protein 31 | chrX | Not Cancer Driver | No | 1 | hippie, biogrid | 26 | 61 | 10 | 10 | 0 |
TMEM67 | TMEM67 | Q5HYA8 | Meckelin | chr8 | Not Cancer Driver | No | 1 | intact, hippie | 120 | 11 | 0 | 0 | 37 |
TNFRSF21 | TNFRSF21 | O75509 | Tumor necrosis factor receptor superfamily member 21 | chr6 | Not Cancer Driver | No | 1 | hippie | 98 | 280 | 46 | 46 | 0 |
TNIP2 | TNIP2 | Q8NFZ5 | TNFAIP3-interacting protein 2 | chr4 | Not Cancer Driver | No | 1 | hippie | 43 | 316 | 36 | 36 | 0 |
TP53BP1_ENST00000263801 | TP53BP1 | Q12888 | TP53-binding protein 1 | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 227 | 1632 | 190 | 190 | 0 |
TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 1 | hippie | 2891 | 282 | 1466 | 1466 | 83 |
TPD52L2_ENST00000346249 | TPD52L2 | O43399 | Tumor protein D54 | chr20 | Not Cancer Driver | No | 1 | hippie, biogrid | 25 | 180 | 22 | 22 | 0 |
TRAF6_ENST00000348124 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 67 | 62 | 7 | 7 | 0 |
TRIM14 | TRIM14 | Q14142 | Tripartite motif-containing protein 14 | chr9 | Not Cancer Driver | No | 1 | hippie | 36 | 93 | 7 | 7 | 0 |
TRIM28 | TRIM28 | Q13263 | Transcription intermediary factor 1-beta | chr19 | Not Cancer Driver | No | 1 | hippie | 87 | 430 | 41 | 41 | 0 |
TRIM63 | TRIM63 | Q969Q1 | E3 ubiquitin-protein ligase TRIM63 | chr1 | Not Cancer Driver | No | 1 | hippie | 47 | 71 | 13 | 13 | 0 |
TXNIP | TXNIP | Q9H3M7 | Thioredoxin-interacting protein | chr1 | Not Cancer Driver | No | 1 | hippie | 61 | 77 | 14 | 14 | 0 |
TXNL1_ENST00000590954 | TXNL1 | O43396 | Thioredoxin-like protein 1 | chr18 | Not Cancer Driver | No | 1 | hippie | 41 | 89 | 4 | 4 | 0 |
UBA52_ENST00000595683 | UBA52 | P62987 | Ubiquitin-60S ribosomal protein L40 | chr19 | Not Cancer Driver | No | 1 | hippie | 19 | 45 | 8 | 8 | 0 |
UBAC1 | UBAC1 | Q9BSL1 | Ubiquitin-associated domain-containing protein 1 | chr9 | Not Cancer Driver | No | 1 | hippie | 38 | 241 | 23 | 23 | 0 |
UBB_ENST00000614404 | UBB | P0CG47 | Polyubiquitin-B | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 20 | 102 | 8 | 8 | 0 |
UBC | UBC | P0CG48 | Polyubiquitin-C | chr12 | Not Cancer Driver | No | 5 | intact | 97 | 312 | 53 | 53 | 0 |
UBD | UBD | O15205 | Ubiquitin D | chr6 | Not Cancer Driver | No | 1 | hippie | 31 | 8 | 1 | 1 | 0 |
UBE2C | UBE2C | O00762 | Ubiquitin-conjugating enzyme E2 C | chr20 | Not Cancer Driver | No | 1 | hippie | 13 | 40 | 0 | 0 | 0 |
UBE2M | UBE2M | P61081 | NEDD8-conjugating enzyme Ubc12 | chr19 | Not Cancer Driver | No | 1 | hippie | 30 | 32 | 6 | 6 | 0 |
UBE3A | UBE3A | Q05086 | Ubiquitin-protein ligase E3A | chr15 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 141 | 136 | 22 | 22 | 0 |
UBLCP1 | UBLCP1 | Q8WVY7 | Ubiquitin-like domain-containing CTD phosphatase 1 | chr5 | Not Cancer Driver | No | 1 | intact, hippie | 39 | 42 | 4 | 4 | 0 |
UBQLN1 | UBQLN1 | Q9UMX0 | Ubiquilin-1 | chr9 | Not Cancer Driver | No | 1 | hippie | 64 | 543 | 58 | 58 | 0 |
UBQLN2 | UBQLN2 | Q9UHD9 | Ubiquilin-2 | chrX | Not Cancer Driver | No | 2 | intact, hippie | 82 | 581 | 79 | 79 | 8 |
UBQLN4 | UBQLN4 | Q9NRR5 | Ubiquilin-4 | chr1 | Not Cancer Driver | No | 1 | hippie | 70 | 561 | 67 | 67 | 1 |
UBXN1_ENST00000301935 | UBXN1 | Q04323 | UBX domain-containing protein 1 | chr11 | Not Cancer Driver | No | 1 | hippie | 35 | 271 | 33 | 33 | 0 |
UCHL5 | UCHL5 | Q9Y5K5 | Ubiquitin carboxyl-terminal hydrolase isozyme L5 | chr1 | Not Cancer Driver | No | 5 | intact, hippie, biogrid | 33 | 41 | 7 | 7 | 0 |
UFL1 | UFL1 | O94874 | E3 UFM1-protein ligase 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 109 | 141 | 24 | 24 | 0 |
USE1 | USE1 | Q9NZ43 | Vesicle transport protein USE1 | chr19 | Not Cancer Driver | No | 1 | biogrid | 31 | 101 | 19 | 19 | 0 |
USP14 | USP14 | P54578 | Ubiquitin carboxyl-terminal hydrolase 14 | chr18 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 59 | 86 | 6 | 6 | 0 |
USP15 | USP15 | Q9Y4E8 | Ubiquitin carboxyl-terminal hydrolase 15 | chr12 | Not Cancer Driver | No | 1 | hippie | 136 | 259 | 39 | 39 | 0 |
USP37_ENST00000454775 | USP37 | Q86T82 | Ubiquitin carboxyl-terminal hydrolase 37 | chr2 | Not Cancer Driver | No | 1 | hippie | 112 | 530 | 62 | 62 | 0 |
USP7 | USP7 | Q93009 | Ubiquitin carboxyl-terminal hydrolase 7 | chr16 | Not Cancer Driver | No | 1 | hippie | 170 | 215 | 45 | 45 | 0 |
VCP | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | Not Cancer Driver | No | 1 | hippie | 88 | 186 | 16 | 16 | 16 |
VIRMA | VIRMA | Q69YN4 | Protein virilizer homolog | chr8 | Not Cancer Driver | No | 1 | hippie | 211 | 631 | 93 | 93 | 0 |
XPC | XPC | Q01831 | DNA repair protein complementing XP-C cells | chr3 | Census, Compendium | Yes | 1 | hippie | 88 | 479 | 48 | 48 | 2 |
XRCC6 | XRCC6 | P12956 | X-ray repair cross-complementing protein 6 | chr22 | Not Cancer Driver | No | 1 | hippie | 66 | 140 | 12 | 12 | 0 |
ZNF24 | ZNF24 | P17028 | Zinc finger protein 24 | chr18 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 187 | 29 | 29 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|