AAK1 |
AAK1 |
Q2M2I8 |
AP2-associated protein kinase 1 |
chr2 |
Not Cancer Driver |
No
|
1 |
intact, hippie, biogrid |
109 |
654 |
70 |
70 |
0 |
ABCE1 |
ABCE1 |
P61221 |
ATP-binding cassette sub-family E member 1 |
chr4 |
Not Cancer Driver |
No
|
1 |
hippie |
74 |
36 |
6 |
6 |
0 |
ABL1_ENST00000318560 |
ABL1 |
P00519 |
Tyrosine-protein kinase ABL1 |
chr9 |
Census, Compendium |
Yes
|
1 |
hippie |
139 |
604 |
73 |
73 |
2 |
ACBD5_ENST00000375888 |
ACBD5 |
Q5T8D3 |
Acyl-CoA-binding domain-containing protein 5 |
chr10 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
65 |
330 |
45 |
45 |
0 |
ACO2 |
ACO2 |
Q99798 |
Aconitate hydratase, mitochondrial |
chr22 |
Not Cancer Driver |
No
|
1 |
hippie |
94 |
172 |
19 |
19 |
5 |
ADRM1 |
ADRM1 |
Q16186 |
Proteasomal ubiquitin receptor ADRM1 |
chr20 |
Not Cancer Driver |
No
|
4 |
hippie, biogrid |
49 |
296 |
40 |
40 |
0 |
AGRN |
AGRN |
O00468 |
Agrin |
chr1 |
Not Cancer Driver |
No
|
1 |
hippie |
188 |
490 |
40 |
40 |
5 |
AHCYL1 |
AHCYL1 |
O43865 |
S-adenosylhomocysteine hydrolase-like protein 1 |
chr1 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
58 |
108 |
10 |
10 |
0 |
AHCYL2 |
AHCYL2 |
Q96HN2 |
Adenosylhomocysteinase 3 |
chr7 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
76 |
208 |
23 |
23 |
0 |
AHR |
AHR |
P35869 |
Aryl hydrocarbon receptor |
chr7 |
Not Cancer Driver |
No
|
1 |
hippie |
129 |
351 |
75 |
75 |
0 |
AIFM1 |
AIFM1 |
O95831 |
Apoptosis-inducing factor 1, mitochondrial |
chrX |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
88 |
166 |
22 |
22 |
11 |
AIMP2 |
AIMP2 |
Q13155 |
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 |
chr7 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
46 |
61 |
8 |
8 |
0 |
ALB |
ALB |
P02768 |
Albumin |
chr4 |
Compendium |
Yes
|
1 |
hippie |
162 |
6 |
0 |
0 |
3 |
ALDOA_ENST00000643777 |
ALDOA |
P04075 |
Fructose-bisphosphate aldolase A |
chr16 |
Not Cancer Driver |
No
|
1 |
hippie |
47 |
65 |
9 |
9 |
3 |
ANKIB1 |
ANKIB1 |
Q9P2G1 |
Ankyrin repeat and IBR domain-containing protein 1 |
chr7 |
Not Cancer Driver |
No
|
1 |
hippie |
141 |
577 |
78 |
78 |
0 |
ANKRD13A |
ANKRD13A |
Q8IZ07 |
Ankyrin repeat domain-containing protein 13A |
chr12 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
54 |
167 |
16 |
16 |
0 |
ANKRD13B |
ANKRD13B |
Q86YJ7 |
Ankyrin repeat domain-containing protein 13B |
chr17 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
64 |
290 |
18 |
18 |
0 |
AP2B1_ENST00000621914 |
AP2B1 |
P63010 |
AP-2 complex subunit beta |
chr17 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
85 |
95 |
12 |
12 |
0 |
APC |
APC |
P25054 |
Adenomatous polyposis coli protein |
chr5 |
Census, Compendium |
Yes
|
1 |
hippie |
412 |
2406 |
345 |
345 |
22 |
APP |
APP |
P05067 |
Amyloid-beta precursor protein |
chr21 |
Not Cancer Driver |
No
|
1 |
hippie |
128 |
418 |
71 |
71 |
17 |
AQP4 |
AQP4 |
P55087 |
Aquaporin-4 |
chr18 |
Not Cancer Driver |
No
|
1 |
hippie |
50 |
30 |
9 |
9 |
0 |
ARL2 |
ARL2 |
P36404 |
ADP-ribosylation factor-like protein 2 |
chr11 |
Not Cancer Driver |
No
|
1 |
biogrid |
19 |
0 |
0 |
0 |
1 |
ATG16L1 |
ATG16L1 |
Q676U5 |
Autophagy-related protein 16-1 |
chr2 |
Not Cancer Driver |
No
|
1 |
hippie |
79 |
239 |
25 |
25 |
1 |
ATP1A3_ENST00000302102 |
ATP1A3 |
P13637 |
Sodium/potassium-transporting ATPase subunit alpha-3 |
chr19 |
Not Cancer Driver |
No
|
1 |
hippie |
200 |
115 |
29 |
29 |
31 |
ATP5F1A_ENST00000282050 |
ATP5F1A |
P25705 |
ATP synthase subunit alpha, mitochondrial |
chr18 |
Not Cancer Driver |
No
|
1 |
hippie |
66 |
23 |
5 |
5 |
2 |
ATP5F1B |
ATP5F1B |
P06576 |
ATP synthase subunit beta, mitochondrial |
chr12 |
Not Cancer Driver |
No
|
1 |
hippie |
60 |
85 |
8 |
8 |
0 |
ATXN3 |
ATXN3 |
P54252 |
Ataxin-3 |
chr14 |
Not Cancer Driver |
No
|
1 |
hippie |
46 |
181 |
24 |
24 |
0 |
BAG1 |
BAG1 |
Q99933 |
BAG family molecular chaperone regulator 1 |
chr9 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
29 |
195 |
9 |
9 |
0 |
BAG6 |
BAG6 |
P46379 |
Large proline-rich protein BAG6 |
chr6 |
Not Cancer Driver |
No
|
1 |
hippie |
98 |
861 |
79 |
79 |
0 |
BAP1 |
BAP1 |
Q92560 |
Ubiquitin carboxyl-terminal hydrolase BAP1 |
chr3 |
Census, Compendium |
Yes
|
1 |
intact, hippie |
141 |
418 |
59 |
59 |
0 |
BCAP31_ENST00000345046 |
BCAP31 |
P51572 |
B-cell receptor-associated protein 31 |
chrX |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
37 |
104 |
14 |
14 |
0 |
BCAR1_ENST00000162330 |
BCAR1 |
P56945 |
Breast cancer anti-estrogen resistance protein 1 |
chr16 |
Not Cancer Driver |
No
|
1 |
hippie |
108 |
677 |
75 |
75 |
0 |
BIRC3_ENST00000532808 |
BIRC3 |
Q13489 |
Baculoviral IAP repeat-containing protein 3 |
chr11 |
Census, Compendium |
Yes
|
1 |
hippie |
77 |
98 |
16 |
16 |
0 |
BRCA1_ENST00000357654 |
BRCA1 |
P38398 |
Breast cancer type 1 susceptibility protein |
chr17 |
Census, Compendium |
Yes
|
1 |
hippie |
224 |
1458 |
174 |
174 |
35 |
BRD4 |
BRD4 |
O60885 |
Bromodomain-containing protein 4 |
chr19 |
Census, Compendium |
Yes
|
1 |
hippie |
193 |
1182 |
172 |
172 |
0 |
BTRC |
BTRC |
Q9Y297 |
F-box/WD repeat-containing protein 1A |
chr10 |
Not Cancer Driver |
No
|
1 |
hippie |
80 |
45 |
4 |
4 |
0 |
C3orf62 |
C3orf62 |
Q6ZUJ4 |
Uncharacterized protein C3orf62 |
chr3 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
31 |
152 |
16 |
16 |
0 |
CAD |
CAD |
P27708 |
CAD protein |
chr2 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
287 |
368 |
52 |
52 |
1 |
CAPZA2 |
CAPZA2 |
P47755 |
F-actin-capping protein subunit alpha-2 |
chr7 |
Not Cancer Driver |
No
|
1 |
hippie |
37 |
19 |
0 |
0 |
0 |
CARS2 |
CARS2 |
Q9HA77 |
Probable cysteine--tRNA ligase, mitochondrial |
chr13 |
Not Cancer Driver |
No
|
1 |
biogrid |
51 |
87 |
8 |
8 |
1 |
CCAR1 |
CCAR1 |
Q8IX12 |
Cell division cycle and apoptosis regulator protein 1 |
chr10 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
145 |
771 |
76 |
76 |
0 |
CCDC74A |
CCDC74A |
Q96AQ1 |
Coiled-coil domain-containing protein 74A |
chr2 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
90 |
351 |
84 |
84 |
0 |
CCDC74B |
CCDC74B |
Q96LY2 |
Coiled-coil domain-containing protein 74B |
chr2 |
Not Cancer Driver |
No
|
3 |
intact, hippie, biogrid |
74 |
339 |
63 |
63 |
0 |
CCDC92 |
CCDC92 |
Q53HC0 |
Coiled-coil domain-containing protein 92 |
chr12 |
Not Cancer Driver |
No
|
3 |
hippie, biogrid |
60 |
299 |
49 |
49 |
0 |
CCNA2_ENST00000618014 |
CCNA2 |
P20248 |
Cyclin-A2 |
chr4 |
Not Cancer Driver |
No
|
1 |
hippie |
45 |
186 |
19 |
19 |
0 |
CCNB1 |
CCNB1 |
P14635 |
G2/mitotic-specific cyclin-B1 |
chr5 |
Not Cancer Driver |
No
|
1 |
hippie |
49 |
145 |
14 |
14 |
0 |
CCNF |
CCNF |
P41002 |
Cyclin-F |
chr16 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
106 |
221 |
23 |
23 |
3 |
CDK9 |
CDK9 |
P50750 |
Cyclin-dependent kinase 9 |
chr9 |
Not Cancer Driver |
No
|
1 |
hippie |
50 |
34 |
2 |
2 |
0 |
CENPP |
CENPP |
Q6IPU0 |
Centromere protein P |
chr9 |
Not Cancer Driver |
No
|
1 |
biogrid |
30 |
40 |
4 |
4 |
0 |
CFTR |
CFTR |
P13569 |
Cystic fibrosis transmembrane conductance regulator |
chr7 |
Not Cancer Driver |
No
|
1 |
hippie |
287 |
145 |
18 |
18 |
151 |
CKM |
CKM |
P06732 |
Creatine kinase M-type |
chr19 |
Not Cancer Driver |
No
|
1 |
hippie |
58 |
118 |
19 |
19 |
0 |
CKMT2_ENST00000437669 |
CKMT2 |
P17540 |
Creatine kinase S-type, mitochondrial |
chr5 |
Not Cancer Driver |
No
|
1 |
hippie |
70 |
68 |
12 |
12 |
0 |
COPS2_ENST00000388901 |
COPS2 |
P61201 |
COP9 signalosome complex subunit 2 |
chr15 |
Not Cancer Driver |
No
|
1 |
hippie |
59 |
59 |
9 |
9 |
0 |
COPS7A_ENST00000534947 |
COPS7A |
Q9UBW8 |
COP9 signalosome complex subunit 7a |
chr12 |
Not Cancer Driver |
No
|
1 |
hippie |
32 |
74 |
10 |
10 |
0 |
CRYAB_ENST00000616970 |
CRYAB |
P02511 |
Alpha-crystallin B chain |
chr11 |
Not Cancer Driver |
No
|
1 |
hippie |
22 |
59 |
11 |
11 |
4 |
CTNNB1_ENST00000643977 |
CTNNB1 |
P35222 |
Catenin beta-1 |
chr3 |
Census, Compendium |
Yes
|
2 |
hippie, biogrid |
415 |
288 |
301 |
301 |
14 |
CUL1_ENST00000602748 |
CUL1 |
Q13616 |
Cullin-1 |
chr7 |
Not Cancer Driver |
No
|
1 |
hippie |
151 |
65 |
9 |
9 |
0 |
CUL2_ENST00000374748 |
CUL2 |
Q13617 |
Cullin-2 |
chr10 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
87 |
66 |
3 |
3 |
0 |
CUL7_ENST00000265348 |
CUL7 |
Q14999 |
Cullin-7 |
chr6 |
Not Cancer Driver |
No
|
1 |
hippie |
188 |
372 |
41 |
41 |
3 |
CWC22 |
CWC22 |
Q9HCG8 |
Pre-mRNA-splicing factor CWC22 homolog |
chr2 |
Not Cancer Driver |
No
|
1 |
biogrid |
104 |
494 |
56 |
56 |
0 |
CYLD |
CYLD |
Q9NQC7 |
Ubiquitin carboxyl-terminal hydrolase CYLD |
chr16 |
Census, Compendium |
Yes
|
1 |
hippie |
116 |
213 |
31 |
31 |
3 |
CYP2C9 |
CYP2C9 |
P11712 |
Cytochrome P450 2C9 |
chr10 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
122 |
36 |
14 |
14 |
0 |
DCLRE1B |
DCLRE1B |
Q9H816 |
5' exonuclease Apollo |
chr1 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
65 |
127 |
17 |
17 |
0 |
DCTN2_ENST00000548249 |
DCTN2 |
Q13561 |
Dynactin subunit 2 |
chr12 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
46 |
253 |
32 |
32 |
0 |
DDRGK1 |
DDRGK1 |
Q96HY6 |
DDRGK domain-containing protein 1 |
chr20 |
Not Cancer Driver |
No
|
1 |
hippie |
34 |
181 |
23 |
23 |
0 |
DESI1 |
DESI1 |
Q6ICB0 |
Desumoylating isopeptidase 1 |
chr22 |
Not Cancer Driver |
No
|
1 |
hippie |
23 |
34 |
6 |
6 |
0 |
DHFR2_ENST00000314636 |
DHFR2 |
Q86XF0 |
Dihydrofolate reductase 2, mitochondrial |
chr3 |
Not Cancer Driver |
No
|
1 |
hippie |
25 |
20 |
0 |
0 |
0 |
DIO2_ENST00000557010 |
DIO2 |
Q92813 |
Type II iodothyronine deiodinase |
chr14 |
Not Cancer Driver |
No
|
1 |
hippie |
73 |
44 |
4 |
4 |
0 |
DIRAS3_ENST00000646789 |
DIRAS3 |
O95661 |
GTP-binding protein Di-Ras3 |
chr1 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
38 |
21 |
3 |
3 |
0 |
DLD |
DLD |
P09622 |
Dihydrolipoyl dehydrogenase, mitochondrial |
chr7 |
Not Cancer Driver |
No
|
2 |
intact, hippie, biogrid |
67 |
17 |
0 |
0 |
10 |
ECPAS_ENST00000338205 |
ECPAS |
Q5VYK3 |
Proteasome adapter and scaffold protein ECM29 |
chr9 |
Not Cancer Driver |
No
|
1 |
hippie |
176 |
240 |
22 |
22 |
0 |
ECT2 |
ECT2 |
Q9H8V3 |
Protein ECT2 |
chr3 |
Not Cancer Driver |
No
|
1 |
hippie |
104 |
284 |
33 |
33 |
0 |
EEF1G |
EEF1G |
P26641 |
Elongation factor 1-gamma |
chr11 |
Not Cancer Driver |
No
|
1 |
biogrid |
44 |
66 |
5 |
5 |
0 |
EGFR |
EGFR |
P00533 |
Epidermal growth factor receptor |
chr7 |
Census, Compendium |
Yes
|
1 |
hippie |
444 |
223 |
35 |
35 |
1 |
EGLN3 |
EGLN3 |
Q9H6Z9 |
Prolyl hydroxylase EGLN3 |
chr14 |
Not Cancer Driver |
No
|
1 |
hippie |
33 |
13 |
0 |
0 |
0 |
EIF3C |
EIF3C |
Q99613 |
Eukaryotic translation initiation factor 3 subunit C |
chr16 |
Not Cancer Driver |
No
|
1 |
biogrid |
15 |
391 |
12 |
12 |
0 |
EIF3D |
EIF3D |
O15371 |
Eukaryotic translation initiation factor 3 subunit D |
chr22 |
Not Cancer Driver |
No
|
1 |
biogrid |
63 |
200 |
26 |
26 |
0 |
ELOC |
ELOC |
Q15369 |
Elongin-C |
chr8 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
22 |
25 |
5 |
5 |
0 |
ELP1 |
ELP1 |
O95163 |
Elongator complex protein 1 |
chr9 |
Not Cancer Driver |
No
|
1 |
hippie |
143 |
157 |
23 |
23 |
2 |
ELSPBP1 |
ELSPBP1 |
Q96BH3 |
Epididymal sperm-binding protein 1 |
chr19 |
Not Cancer Driver |
No
|
1 |
hippie |
54 |
0 |
0 |
0 |
0 |
EPM2A |
EPM2A |
O95278 |
Laforin |
chr6 |
Not Cancer Driver |
No
|
1 |
hippie |
29 |
46 |
1 |
1 |
19 |
EPN1_ENST00000270460 |
EPN1 |
Q9Y6I3 |
Epsin-1 |
chr19 |
Not Cancer Driver |
No
|
1 |
hippie |
87 |
493 |
71 |
71 |
0 |
EPS15 |
EPS15 |
P42566 |
Epidermal growth factor receptor substrate 15 |
chr1 |
Census, Compendium |
Yes
|
1 |
hippie |
106 |
543 |
66 |
66 |
0 |
ESR2 |
ESR2 |
Q92731 |
Estrogen receptor beta |
chr14 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
90 |
92 |
11 |
11 |
1 |
FAM90A1 |
FAM90A1 |
Q86YD7 |
Protein FAM90A1 |
chr12 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
123 |
461 |
121 |
121 |
0 |
FARSA |
FARSA |
Q9Y285 |
Phenylalanine--tRNA ligase alpha subunit |
chr19 |
Not Cancer Driver |
No
|
1 |
biogrid |
75 |
120 |
25 |
25 |
0 |
FBXO25 |
FBXO25 |
Q8TCJ0 |
F-box only protein 25 |
chr8 |
Not Cancer Driver |
No
|
1 |
hippie |
33 |
20 |
0 |
0 |
0 |
FBXO6 |
FBXO6 |
Q9NRD1 |
F-box only protein 6 |
chr1 |
Not Cancer Driver |
No
|
1 |
hippie |
31 |
27 |
3 |
3 |
0 |
FKBP8_ENST00000222308 |
FKBP8 |
Q14318 |
Peptidyl-prolyl cis-trans isomerase FKBP8 |
chr19 |
Not Cancer Driver |
No
|
1 |
hippie |
71 |
160 |
25 |
25 |
0 |
FLOT1 |
FLOT1 |
O75955 |
Flotillin-1 |
chr6 |
Not Cancer Driver |
No
|
1 |
hippie |
43 |
122 |
15 |
15 |
0 |
FZR1 |
FZR1 |
Q9UM11 |
Fizzy-related protein homolog |
chr19 |
Not Cancer Driver |
No
|
1 |
hippie |
74 |
184 |
30 |
30 |
0 |
GFPT1 |
GFPT1 |
Q06210 |
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 |
chr2 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
81 |
75 |
8 |
8 |
13 |
GGA1 |
GGA1 |
Q9UJY5 |
ADP-ribosylation factor-binding protein GGA1 |
chr22 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
75 |
385 |
33 |
33 |
0 |
GJA1 |
GJA1 |
P17302 |
Gap junction alpha-1 protein |
chr6 |
Not Cancer Driver |
No
|
1 |
hippie |
86 |
110 |
26 |
26 |
50 |
GJD3 |
GJD3 |
Q8N144 |
Gap junction delta-3 protein |
chr17 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
5 |
79 |
0 |
0 |
0 |
GNB5 |
GNB5 |
O14775 |
Guanine nucleotide-binding protein subunit beta-5 |
chr15 |
Not Cancer Driver |
No
|
1 |
hippie |
60 |
16 |
1 |
1 |
1 |
GNL3L_ENST00000360845 |
GNL3L |
Q9NVN8 |
Guanine nucleotide-binding protein-like 3-like protein |
chrX |
Not Cancer Driver |
No
|
1 |
biogrid |
120 |
242 |
43 |
43 |
0 |
GOLGA2_ENST00000611957 |
GOLGA2 |
Q08379 |
Golgin subfamily A member 2 |
chr9 |
Not Cancer Driver |
No
|
2 |
intact, hippie, biogrid |
115 |
854 |
96 |
96 |
0 |
GOT2 |
GOT2 |
P00505 |
Aspartate aminotransferase, mitochondrial |
chr16 |
Not Cancer Driver |
No
|
1 |
hippie |
61 |
25 |
3 |
3 |
1 |
GSN |
GSN |
P06396 |
Gelsolin |
chr9 |
Not Cancer Driver |
No
|
1 |
hippie |
76 |
316 |
28 |
28 |
2 |
HADHA |
HADHA |
P40939 |
Trifunctional enzyme subunit alpha, mitochondrial |
chr2 |
Not Cancer Driver |
No
|
1 |
hippie |
72 |
19 |
2 |
2 |
5 |
HERC3 |
HERC3 |
Q15034 |
Probable E3 ubiquitin-protein ligase HERC3 |
chr4 |
Not Cancer Driver |
No
|
1 |
hippie |
112 |
56 |
7 |
7 |
0 |
HEXIM1 |
HEXIM1 |
O94992 |
Protein HEXIM1 |
chr17 |
Not Cancer Driver |
No
|
1 |
hippie |
40 |
352 |
40 |
40 |
0 |
HIF1AN |
HIF1AN |
Q9NWT6 |
Hypoxia-inducible factor 1-alpha inhibitor |
chr10 |
Not Cancer Driver |
No
|
1 |
hippie |
37 |
77 |
9 |
9 |
0 |
HLA-B |
HLA-B |
P01889 |
HLA class I histocompatibility antigen, B alpha chain |
chr6 |
Compendium |
Yes
|
1 |
hippie |
78 |
169 |
34 |
34 |
0 |
HSPA4 |
HSPA4 |
P34932 |
Heat shock 70 kDa protein 4 |
chr5 |
Not Cancer Driver |
No
|
1 |
hippie |
80 |
351 |
24 |
24 |
0 |
HSPA8_ENST00000532636 |
HSPA8 |
P11142 |
Heat shock cognate 71 kDa protein |
chr11 |
Not Cancer Driver |
No
|
1 |
hippie |
149 |
251 |
52 |
52 |
0 |
HTT |
HTT |
P42858 |
Huntingtin |
chr4 |
Not Cancer Driver |
No
|
2 |
intact, hippie |
336 |
666 |
69 |
69 |
2 |
HUWE1_ENST00000262854 |
HUWE1 |
Q7Z6Z7 |
E3 ubiquitin-protein ligase HUWE1 |
chrX |
Not Cancer Driver |
No
|
1 |
hippie |
669 |
2091 |
329 |
329 |
21 |
ID1 |
ID1 |
P41134 |
DNA-binding protein inhibitor ID-1 |
chr20 |
Not Cancer Driver |
No
|
2 |
intact, hippie |
20 |
17 |
6 |
6 |
0 |
IDH3A |
IDH3A |
P50213 |
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial |
chr15 |
Not Cancer Driver |
No
|
1 |
hippie |
41 |
47 |
11 |
11 |
0 |
IFITM1_ENST00000528780 |
IFITM1 |
P13164 |
Interferon-induced transmembrane protein 1 |
chr11 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
19 |
0 |
0 |
0 |
0 |
IFITM3 |
IFITM3 |
Q01628 |
Interferon-induced transmembrane protein 3 |
chr11 |
Not Cancer Driver |
No
|
2 |
intact, hippie, biogrid |
69 |
18 |
5 |
5 |
0 |
IMPDH2 |
IMPDH2 |
P12268 |
Inosine-5'-monophosphate dehydrogenase 2 |
chr3 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
70 |
6 |
1 |
1 |
0 |
INS |
INS |
P01308 |
Insulin |
chr11 |
Not Cancer Driver |
No
|
1 |
hippie |
15 |
5 |
1 |
1 |
22 |
INSIG2 |
INSIG2 |
Q9Y5U4 |
Insulin-induced gene 2 protein |
chr2 |
Not Cancer Driver |
No
|
1 |
hippie |
47 |
11 |
3 |
3 |
0 |
INTS5 |
INTS5 |
Q6P9B9 |
Integrator complex subunit 5 |
chr11 |
Not Cancer Driver |
No
|
1 |
biogrid |
123 |
189 |
22 |
22 |
0 |
ITGA2 |
ITGA2 |
P17301 |
Integrin alpha-2 |
chr5 |
Not Cancer Driver |
No
|
1 |
hippie |
166 |
26 |
0 |
0 |
0 |
ITGB2_ENST00000355153 |
ITGB2 |
P05107 |
Integrin beta-2 |
chr21 |
Not Cancer Driver |
No
|
1 |
hippie |
147 |
59 |
9 |
9 |
15 |
JAZF1 |
JAZF1 |
Q86VZ6 |
Juxtaposed with another zinc finger protein 1 |
chr7 |
Census |
Yes
|
1 |
intact, hippie |
29 |
172 |
21 |
21 |
0 |
JUN |
JUN |
P05412 |
Transcription factor Jun |
chr1 |
Census |
Yes
|
1 |
hippie |
35 |
281 |
25 |
25 |
0 |
KDELR1 |
KDELR1 |
P24390 |
ER lumen protein-retaining receptor 1 |
chr19 |
Not Cancer Driver |
No
|
1 |
intact, hippie, biogrid |
32 |
0 |
0 |
0 |
0 |
KEAP1_ENST00000393623 |
KEAP1 |
Q14145 |
Kelch-like ECH-associated protein 1 |
chr19 |
Census, Compendium |
Yes
|
1 |
hippie |
237 |
57 |
12 |
12 |
0 |
KIF14 |
KIF14 |
Q15058 |
Kinesin-like protein KIF14 |
chr1 |
Not Cancer Driver |
No
|
1 |
hippie |
222 |
774 |
102 |
102 |
2 |
KLF16 |
KLF16 |
Q9BXK1 |
Krueppel-like factor 16 |
chr19 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
13 |
204 |
8 |
8 |
0 |
KLF8 |
KLF8 |
O95600 |
Krueppel-like factor 8 |
chrX |
Not Cancer Driver |
No
|
1 |
intact, hippie |
71 |
270 |
53 |
53 |
0 |
LAGE3 |
LAGE3 |
Q14657 |
EKC/KEOPS complex subunit LAGE3 |
chrX |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
16 |
95 |
8 |
8 |
2 |
LARP7_ENST00000344442 |
LARP7 |
Q4G0J3 |
La-related protein 7 |
chr4 |
Not Cancer Driver |
No
|
1 |
hippie |
58 |
350 |
44 |
44 |
0 |
LRRK2 |
LRRK2 |
Q5S007 |
Leucine-rich repeat serine/threonine-protein kinase 2 |
chr12 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
519 |
90 |
17 |
17 |
23 |
MAF_ENST00000393350 |
MAF |
O75444 |
Transcription factor Maf |
chr16 |
Census, Compendium |
Yes
|
1 |
hippie |
39 |
331 |
37 |
37 |
11 |
MAP1LC3A_ENST00000397709 |
MAP1LC3A |
Q9H492 |
Microtubule-associated proteins 1A/1B light chain 3A |
chr20 |
Not Cancer Driver |
No
|
1 |
hippie |
22 |
24 |
1 |
1 |
0 |
MAP3K1 |
MAP3K1 |
Q13233 |
Mitogen-activated protein kinase kinase kinase 1 |
chr5 |
Census, Compendium |
Yes
|
1 |
hippie |
184 |
820 |
62 |
62 |
3 |
MAPK6 |
MAPK6 |
Q16659 |
Mitogen-activated protein kinase 6 |
chr15 |
Not Cancer Driver |
No
|
1 |
hippie |
79 |
165 |
20 |
20 |
0 |
MAPT_ENST00000262410 |
MAPT |
P10636 |
Microtubule-associated protein tau |
chr17 |
Not Cancer Driver |
No
|
1 |
hippie |
128 |
750 |
126 |
126 |
18 |
MBTPS2 |
MBTPS2 |
O43462 |
Membrane-bound transcription factor site-2 protease |
chrX |
Not Cancer Driver |
No
|
1 |
biogrid |
63 |
16 |
4 |
4 |
9 |
MB_ENST00000397328 |
MB |
P02144 |
Myoglobin |
chr22 |
Not Cancer Driver |
No
|
1 |
hippie |
13 |
38 |
4 |
4 |
0 |
MCFD2_ENST00000409973 |
MCFD2 |
Q8NI22 |
Multiple coagulation factor deficiency protein 2 |
chr2 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
16 |
90 |
11 |
11 |
4 |
MCM5 |
MCM5 |
P33992 |
DNA replication licensing factor MCM5 |
chr22 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
88 |
109 |
20 |
20 |
1 |
MDC1 |
MDC1 |
Q14676 |
Mediator of DNA damage checkpoint protein 1 |
chr6 |
Not Cancer Driver |
No
|
1 |
hippie |
249 |
1829 |
223 |
223 |
0 |
MDH2 |
MDH2 |
P40926 |
Malate dehydrogenase, mitochondrial |
chr7 |
Not Cancer Driver |
No
|
1 |
hippie |
39 |
8 |
1 |
1 |
3 |
MDM2_ENST00000539479 |
MDM2 |
Q00987 |
E3 ubiquitin-protein ligase Mdm2 |
chr12 |
Census, Compendium |
Yes
|
1 |
hippie |
56 |
297 |
37 |
37 |
0 |
MED1 |
MED1 |
Q15648 |
Mediator of RNA polymerase II transcription subunit 1 |
chr17 |
Not Cancer Driver |
No
|
1 |
biogrid |
162 |
1104 |
117 |
117 |
0 |
MED24_ENST00000394128 |
MED24 |
O75448 |
Mediator of RNA polymerase II transcription subunit 24 |
chr17 |
Not Cancer Driver |
No
|
1 |
biogrid |
101 |
76 |
0 |
0 |
0 |
MEPCE |
MEPCE |
Q7L2J0 |
7SK snRNA methylphosphate capping enzyme |
chr7 |
Not Cancer Driver |
No
|
1 |
hippie |
76 |
446 |
42 |
42 |
0 |
MFAP1 |
MFAP1 |
P55081 |
Microfibrillar-associated protein 1 |
chr15 |
Not Cancer Driver |
No
|
1 |
biogrid |
58 |
377 |
53 |
53 |
0 |
MFN2_ENST00000444836 |
MFN2 |
O95140 |
Mitofusin-2 |
chr1 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
80 |
81 |
9 |
9 |
20 |
MKRN1 |
MKRN1 |
Q9UHC7 |
E3 ubiquitin-protein ligase makorin-1 |
chr7 |
Not Cancer Driver |
No
|
1 |
hippie |
42 |
155 |
16 |
16 |
0 |
MRPL15 |
MRPL15 |
Q9P015 |
39S ribosomal protein L15, mitochondrial |
chr8 |
Not Cancer Driver |
No
|
1 |
biogrid |
32 |
81 |
3 |
3 |
0 |
MRPL22 |
MRPL22 |
Q9NWU5 |
39S ribosomal protein L22, mitochondrial |
chr5 |
Not Cancer Driver |
No
|
1 |
biogrid |
23 |
28 |
2 |
2 |
0 |
MRPL43_ENST00000318325 |
MRPL43 |
Q8N983 |
39S ribosomal protein L43, mitochondrial |
chr10 |
Not Cancer Driver |
No
|
1 |
biogrid |
17 |
66 |
6 |
6 |
0 |
MRPL57 |
MRPL57 |
Q9BQC6 |
Ribosomal protein 63, mitochondrial |
chr13 |
Not Cancer Driver |
No
|
1 |
biogrid |
11 |
9 |
1 |
1 |
0 |
MSH6 |
MSH6 |
P52701 |
DNA mismatch repair protein Msh6 |
chr2 |
Census |
Yes
|
1 |
intact, hippie |
154 |
386 |
41 |
41 |
6 |
MYC_ENST00000377970 |
MYC |
P01106 |
Myc proto-oncogene protein |
chr8 |
Census, Compendium |
Yes
|
1 |
hippie |
80 |
299 |
46 |
46 |
0 |
MYH7 |
MYH7 |
P12883 |
Myosin-7 |
chr14 |
Not Cancer Driver |
No
|
1 |
hippie |
464 |
1107 |
276 |
276 |
200 |
MYOD1 |
MYOD1 |
P15172 |
Myoblast determination protein 1 |
chr11 |
Census |
Yes
|
1 |
hippie |
45 |
246 |
33 |
33 |
0 |
NAA40 |
NAA40 |
Q86UY6 |
N-alpha-acetyltransferase 40 |
chr11 |
Not Cancer Driver |
No
|
1 |
hippie |
22 |
30 |
3 |
3 |
0 |
NAP1L1 |
NAP1L1 |
P55209 |
Nucleosome assembly protein 1-like 1 |
chr12 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
47 |
207 |
31 |
31 |
0 |
NCAPD3 |
NCAPD3 |
P42695 |
Condensin-2 complex subunit D3 |
chr11 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
193 |
304 |
42 |
42 |
1 |
NDUFB1_ENST00000605997 |
NDUFB1 |
O75438 |
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 |
chr14 |
Not Cancer Driver |
No
|
1 |
biogrid |
5 |
0 |
0 |
0 |
0 |
NDUFB2_ENST00000247866 |
NDUFB2 |
O95178 |
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial |
chr7 |
Not Cancer Driver |
No
|
1 |
biogrid |
13 |
26 |
3 |
3 |
0 |
NEDD4 |
NEDD4 |
P46934 |
E3 ubiquitin-protein ligase NEDD4 |
chr15 |
Not Cancer Driver |
No
|
1 |
hippie |
150 |
711 |
79 |
79 |
0 |
NEDD4L |
NEDD4L |
Q96PU5 |
E3 ubiquitin-protein ligase NEDD4-like |
chr18 |
Not Cancer Driver |
No
|
1 |
hippie |
126 |
463 |
60 |
60 |
4 |
NEDD8 |
NEDD8 |
Q15843 |
NEDD8 |
chr14 |
Not Cancer Driver |
No
|
1 |
hippie |
10 |
36 |
5 |
5 |
0 |
NEMF |
NEMF |
O60524 |
Ribosome quality control complex subunit NEMF |
chr14 |
Not Cancer Driver |
No
|
1 |
biogrid |
109 |
517 |
61 |
61 |
0 |
NEURL4 |
NEURL4 |
Q96JN8 |
Neuralized-like protein 4 |
chr17 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
217 |
751 |
119 |
119 |
0 |
NFX1 |
NFX1 |
Q12986 |
Transcriptional repressor NF-X1 |
chr9 |
Not Cancer Driver |
No
|
1 |
hippie |
121 |
491 |
46 |
46 |
0 |
NOS2 |
NOS2 |
P35228 |
Nitric oxide synthase, inducible |
chr17 |
Not Cancer Driver |
No
|
1 |
hippie |
207 |
201 |
33 |
33 |
0 |
NPM1 |
NPM1 |
P06748 |
Nucleophosmin |
chr5 |
Census, Compendium |
Yes
|
1 |
hippie |
29 |
249 |
22 |
22 |
0 |
NTRK1 |
NTRK1 |
P04629 |
High affinity nerve growth factor receptor |
chr1 |
Census, Compendium |
Yes
|
1 |
hippie |
168 |
57 |
8 |
8 |
25 |
NUB1_ENST00000470229 |
NUB1 |
Q9Y5A7 |
NEDD8 ultimate buster 1 |
chr7 |
Not Cancer Driver |
No
|
1 |
hippie |
52 |
180 |
15 |
15 |
0 |
NUBP2 |
NUBP2 |
Q9Y5Y2 |
Cytosolic Fe-S cluster assembly factor NUBP2 |
chr16 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
38 |
14 |
0 |
0 |
0 |
NUPR1_ENST00000324873 |
NUPR1 |
O60356 |
Nuclear protein 1 |
chr16 |
Not Cancer Driver |
No
|
2 |
intact, hippie |
10 |
82 |
10 |
10 |
0 |
OGT |
OGT |
O15294 |
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit |
chrX |
Not Cancer Driver |
No
|
1 |
hippie |
156 |
89 |
16 |
16 |
2 |
PAAF1 |
PAAF1 |
Q9BRP4 |
Proteasomal ATPase-associated factor 1 |
chr11 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
47 |
23 |
3 |
3 |
0 |
PAGE4_ENST00000376141 |
PAGE4 |
O60829 |
P antigen family member 4 |
chrX |
Not Cancer Driver |
No
|
1 |
hippie |
20 |
102 |
20 |
20 |
0 |
PAX3_ENST00000350526 |
PAX3 |
P23760 |
Paired box protein Pax-3 |
chr2 |
Census |
Yes
|
1 |
hippie |
113 |
391 |
95 |
95 |
28 |
PCNT |
PCNT |
O95613 |
Pericentrin |
chr21 |
Not Cancer Driver |
No
|
1 |
hippie |
436 |
2474 |
337 |
337 |
0 |
PDIA4 |
PDIA4 |
P13667 |
Protein disulfide-isomerase A4 |
chr7 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
81 |
147 |
22 |
22 |
0 |
PDIA6_ENST00000272227 |
PDIA6 |
Q15084 |
Protein disulfide-isomerase A6 |
chr2 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
55 |
82 |
11 |
11 |
0 |
PELO |
PELO |
Q9BRX2 |
Protein pelota homolog |
chr5 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
38 |
67 |
10 |
10 |
0 |
PIH1D1 |
PIH1D1 |
Q9NWS0 |
PIH1 domain-containing protein 1 |
chr19 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
30 |
157 |
13 |
13 |
0 |
PIK3C3 |
PIK3C3 |
Q8NEB9 |
Phosphatidylinositol 3-kinase catalytic subunit type 3 |
chr18 |
Not Cancer Driver |
No
|
1 |
hippie |
127 |
191 |
34 |
34 |
0 |
PLEKHA4 |
PLEKHA4 |
Q9H4M7 |
Pleckstrin homology domain-containing family A member 4 |
chr19 |
Not Cancer Driver |
No
|
1 |
hippie |
136 |
687 |
128 |
128 |
0 |
POLE |
POLE |
Q07864 |
DNA polymerase epsilon catalytic subunit A |
chr12 |
Census, Compendium |
Yes
|
1 |
hippie, biogrid |
409 |
239 |
44 |
44 |
3 |
PPIA |
PPIA |
P62937 |
Peptidyl-prolyl cis-trans isomerase A |
chr7 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
11 |
24 |
3 |
3 |
0 |
PPM1D |
PPM1D |
O15297 |
Protein phosphatase 1D |
chr17 |
Census, Compendium |
Yes
|
1 |
hippie |
54 |
370 |
32 |
32 |
0 |
PPP6C_ENST00000373547 |
PPP6C |
O00743 |
Serine/threonine-protein phosphatase 6 catalytic subunit |
chr9 |
Census, Compendium |
Yes
|
1 |
hippie |
63 |
0 |
0 |
0 |
0 |
PRKN |
PRKN |
O60260 |
E3 ubiquitin-protein ligase parkin |
chr6 |
Not Cancer Driver |
No
|
1 |
hippie |
110 |
78 |
15 |
15 |
31 |
PRPS2_ENST00000380668 |
PRPS2 |
P11908 |
Ribose-phosphate pyrophosphokinase 2 |
chrX |
Not Cancer Driver |
No
|
1 |
hippie |
56 |
4 |
1 |
1 |
0 |
PSMA1_ENST00000396394 |
PSMA1 |
P25786 |
Proteasome subunit alpha type-1 |
chr11 |
Not Cancer Driver |
No
|
3 |
intact, hippie, biogrid |
48 |
51 |
9 |
9 |
0 |
PSMA2 |
PSMA2 |
P25787 |
Proteasome subunit alpha type-2 |
chr7 |
Not Cancer Driver |
No
|
3 |
intact, hippie, biogrid |
20 |
0 |
0 |
0 |
0 |
PSMA3 |
PSMA3 |
P25788 |
Proteasome subunit alpha type-3 |
chr14 |
Not Cancer Driver |
No
|
3 |
intact, hippie, biogrid |
27 |
30 |
5 |
5 |
0 |
PSMA4_ENST00000559082 |
PSMA4 |
P25789 |
Proteasome subunit alpha type-4 |
chr15 |
Not Cancer Driver |
No
|
3 |
intact, hippie, biogrid |
29 |
28 |
9 |
9 |
0 |
PSMA5 |
PSMA5 |
P28066 |
Proteasome subunit alpha type-5 |
chr1 |
Not Cancer Driver |
No
|
5 |
intact, hippie, biogrid |
24 |
23 |
1 |
1 |
0 |
PSMA6 |
PSMA6 |
P60900 |
Proteasome subunit alpha type-6 |
chr14 |
Not Cancer Driver |
No
|
4 |
intact, hippie, biogrid |
37 |
2 |
1 |
1 |
0 |
PSMA7 |
PSMA7 |
O14818 |
Proteasome subunit alpha type-7 |
chr20 |
Not Cancer Driver |
No
|
3 |
intact, hippie, biogrid |
24 |
23 |
1 |
1 |
0 |
PSMA8 |
PSMA8 |
Q8TAA3 |
Proteasome subunit alpha-type 8 |
chr18 |
Not Cancer Driver |
No
|
1 |
intact |
42 |
15 |
5 |
5 |
0 |
PSMB1 |
PSMB1 |
P20618 |
Proteasome subunit beta type-1 |
chr6 |
Not Cancer Driver |
No
|
4 |
intact, hippie, biogrid |
25 |
14 |
2 |
2 |
0 |
PSMB10 |
PSMB10 |
P40306 |
Proteasome subunit beta type-10 |
chr16 |
Not Cancer Driver |
No
|
2 |
intact, hippie, biogrid |
22 |
36 |
5 |
5 |
0 |
PSMB2 |
PSMB2 |
P49721 |
Proteasome subunit beta type-2 |
chr1 |
Not Cancer Driver |
No
|
3 |
intact, hippie, biogrid |
24 |
0 |
0 |
0 |
0 |
PSMB4 |
PSMB4 |
P28070 |
Proteasome subunit beta type-4 |
chr1 |
Not Cancer Driver |
No
|
3 |
intact, hippie, biogrid |
23 |
18 |
2 |
2 |
0 |
PSMB5 |
PSMB5 |
P28074 |
Proteasome subunit beta type-5 |
chr14 |
Not Cancer Driver |
No
|
3 |
intact, hippie, biogrid |
39 |
9 |
0 |
0 |
0 |
PSMB6 |
PSMB6 |
P28072 |
Proteasome subunit beta type-6 |
chr17 |
Not Cancer Driver |
No
|
3 |
intact, hippie, biogrid |
19 |
22 |
1 |
1 |
0 |
PSMB7 |
PSMB7 |
Q99436 |
Proteasome subunit beta type-7 |
chr9 |
Not Cancer Driver |
No
|
4 |
intact, hippie, biogrid |
25 |
26 |
3 |
3 |
0 |
PSMB8 |
PSMB8 |
P28062 |
Proteasome subunit beta type-8 |
chr6 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
43 |
62 |
7 |
7 |
3 |
PSMB9 |
PSMB9 |
P28065 |
Proteasome subunit beta type-9 |
chr6 |
Not Cancer Driver |
No
|
3 |
intact, hippie, biogrid |
21 |
17 |
1 |
1 |
1 |
PSMC1 |
PSMC1 |
P62191 |
26S proteasome regulatory subunit 4 |
chr14 |
Not Cancer Driver |
No
|
5 |
intact, hippie, biogrid |
36 |
165 |
10 |
10 |
0 |
PSMC2_ENST00000292644 |
PSMC2 |
P35998 |
26S proteasome regulatory subunit 7 |
chr7 |
Not Cancer Driver |
No
|
5 |
intact, hippie, biogrid |
63 |
120 |
13 |
13 |
0 |
PSMC3_ENST00000298852 |
PSMC3 |
P17980 |
26S proteasome regulatory subunit 6A |
chr11 |
Not Cancer Driver |
No
|
5 |
intact, hippie, biogrid |
55 |
131 |
10 |
10 |
0 |
PSMC4 |
PSMC4 |
P43686 |
26S proteasome regulatory subunit 6B |
chr19 |
Not Cancer Driver |
No
|
4 |
hippie, biogrid |
51 |
21 |
3 |
3 |
0 |
PSMC5 |
PSMC5 |
P62195 |
26S proteasome regulatory subunit 8 |
chr17 |
Not Cancer Driver |
No
|
5 |
intact, hippie, biogrid |
52 |
64 |
6 |
6 |
0 |
PSMC6_ENST00000606149 |
PSMC6 |
P62333 |
26S proteasome regulatory subunit 10B |
chr14 |
Not Cancer Driver |
No
|
6 |
intact, hippie, biogrid |
49 |
69 |
8 |
8 |
0 |
PSMD1 |
PSMD1 |
Q99460 |
26S proteasome non-ATPase regulatory subunit 1 |
chr2 |
Not Cancer Driver |
No
|
5 |
intact, hippie, biogrid |
110 |
201 |
19 |
19 |
0 |
PSMD10 |
PSMD10 |
O75832 |
26S proteasome non-ATPase regulatory subunit 10 |
chrX |
Not Cancer Driver |
No
|
4 |
hippie, biogrid |
20 |
53 |
5 |
5 |
0 |
PSMD11_ENST00000457654 |
PSMD11 |
O00231 |
26S proteasome non-ATPase regulatory subunit 11 |
chr17 |
Not Cancer Driver |
No
|
6 |
intact, hippie, biogrid |
51 |
0 |
0 |
0 |
0 |
PSMD12 |
PSMD12 |
O00232 |
26S proteasome non-ATPase regulatory subunit 12 |
chr17 |
Not Cancer Driver |
No
|
4 |
intact, hippie, biogrid |
48 |
24 |
3 |
3 |
0 |
PSMD13_ENST00000532097 |
PSMD13 |
Q9UNM6 |
26S proteasome non-ATPase regulatory subunit 13 |
chr11 |
Not Cancer Driver |
No
|
5 |
intact, hippie, biogrid |
30 |
13 |
3 |
3 |
0 |
PSMD14 |
PSMD14 |
O00487 |
26S proteasome non-ATPase regulatory subunit 14 |
chr2 |
Not Cancer Driver |
No
|
5 |
intact, hippie, biogrid |
23 |
67 |
6 |
6 |
0 |
PSMD2 |
PSMD2 |
Q13200 |
26S proteasome non-ATPase regulatory subunit 2 |
chr3 |
Not Cancer Driver |
No
|
6 |
intact, hippie, biogrid |
100 |
135 |
14 |
14 |
0 |
PSMD3 |
PSMD3 |
O43242 |
26S proteasome non-ATPase regulatory subunit 3 |
chr17 |
Not Cancer Driver |
No
|
5 |
intact, hippie, biogrid |
69 |
152 |
19 |
19 |
0 |
PSMD4_ENST00000368884 |
PSMD4 |
P55036 |
26S proteasome non-ATPase regulatory subunit 4 |
chr1 |
Not Cancer Driver |
No
|
2 |
intact, hippie |
43 |
243 |
25 |
25 |
0 |
PSMD5 |
PSMD5 |
Q16401 |
26S proteasome non-ATPase regulatory subunit 5 |
chr9 |
Not Cancer Driver |
No
|
3 |
hippie, biogrid |
43 |
2 |
1 |
1 |
0 |
PSMD6_ENST00000295901 |
PSMD6 |
Q15008 |
26S proteasome non-ATPase regulatory subunit 6 |
chr3 |
Not Cancer Driver |
No
|
6 |
intact, hippie, biogrid |
33 |
40 |
3 |
3 |
0 |
PSMD7 |
PSMD7 |
P51665 |
26S proteasome non-ATPase regulatory subunit 7 |
chr16 |
Not Cancer Driver |
No
|
7 |
intact, hippie, biogrid |
39 |
70 |
4 |
4 |
0 |
PSMD8 |
PSMD8 |
P48556 |
26S proteasome non-ATPase regulatory subunit 8 |
chr19 |
Not Cancer Driver |
No
|
5 |
intact, hippie, biogrid |
20 |
78 |
2 |
2 |
0 |
PSMD9 |
PSMD9 |
O00233 |
26S proteasome non-ATPase regulatory subunit 9 |
chr12 |
Not Cancer Driver |
No
|
2 |
hippie, biogrid |
22 |
173 |
16 |
16 |
0 |
PSME3_ENST00000590720 |
PSME3 |
P61289 |
Proteasome activator complex subunit 3 |
chr17 |
Not Cancer Driver |
No
|
1 |
hippie |
20 |
25 |
5 |
5 |
0 |
PTEN |
PTEN |
P60484 |
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN |
chr10 |
Census, Compendium |
Yes
|
1 |
hippie |
505 |
76 |
4 |
4 |
41 |
PTPN2 |
PTPN2 |
P17706 |
Tyrosine-protein phosphatase non-receptor type 2 |
chr18 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
57 |
120 |
14 |
14 |
0 |
PTPN6_ENST00000318974 |
PTPN6 |
P29350 |
Tyrosine-protein phosphatase non-receptor type 6 |
chr12 |
Census, Compendium |
Yes
|
1 |
intact, hippie |
73 |
192 |
25 |
25 |
0 |
PTPRA_ENST00000399903 |
PTPRA |
P18433 |
Receptor-type tyrosine-protein phosphatase alpha |
chr20 |
Not Cancer Driver |
No
|
1 |
hippie |
98 |
210 |
21 |
21 |
0 |
PTPRM_ENST00000332175 |
PTPRM |
P28827 |
Receptor-type tyrosine-protein phosphatase mu |
chr18 |
Not Cancer Driver |
No
|
1 |
hippie |
256 |
365 |
60 |
60 |
0 |
PXMP2 |
PXMP2 |
Q9NR77 |
Peroxisomal membrane protein 2 |
chr12 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
15 |
0 |
0 |
0 |
0 |
RAD23A |
RAD23A |
P54725 |
UV excision repair protein RAD23 homolog A |
chr19 |
Not Cancer Driver |
No
|
7 |
intact, hippie |
50 |
283 |
41 |
41 |
0 |
RAD23B |
RAD23B |
P54727 |
UV excision repair protein RAD23 homolog B |
chr9 |
Not Cancer Driver |
No
|
2 |
hippie, biogrid |
54 |
324 |
41 |
41 |
0 |
RASSF8_ENST00000541490 |
RASSF8 |
Q8NHQ8 |
Ras association domain-containing protein 8 |
chr12 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
47 |
206 |
19 |
19 |
0 |
RBCK1 |
RBCK1 |
Q9BYM8 |
RanBP-type and C3HC4-type zinc finger-containing protein 1 |
chr20 |
Not Cancer Driver |
No
|
1 |
hippie |
52 |
140 |
14 |
14 |
2 |
RELA |
RELA |
Q04206 |
Transcription factor p65 |
chr11 |
Compendium |
Yes
|
1 |
hippie |
75 |
400 |
48 |
48 |
0 |
RNF11 |
RNF11 |
Q9Y3C5 |
RING finger protein 11 |
chr1 |
Not Cancer Driver |
No
|
1 |
hippie |
17 |
76 |
7 |
7 |
0 |
RNF4 |
RNF4 |
P78317 |
E3 ubiquitin-protein ligase RNF4 |
chr4 |
Not Cancer Driver |
No
|
1 |
hippie |
14 |
117 |
7 |
7 |
0 |
RPA1 |
RPA1 |
P27694 |
Replication protein A 70 kDa DNA-binding subunit |
chr17 |
Not Cancer Driver |
No
|
1 |
hippie |
51 |
98 |
6 |
6 |
0 |
RPL11 |
RPL11 |
P62913 |
60S ribosomal protein L11 |
chr1 |
Not Cancer Driver |
No
|
1 |
biogrid |
27 |
12 |
1 |
1 |
1 |
RPS12 |
RPS12 |
P25398 |
40S ribosomal protein S12 |
chr6 |
Not Cancer Driver |
No
|
1 |
hippie |
17 |
0 |
0 |
0 |
0 |
RPS20_ENST00000521262 |
RPS20 |
P60866 |
40S ribosomal protein S20 |
chr8 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
18 |
53 |
8 |
8 |
0 |
RPS6 |
RPS6 |
P62753 |
40S ribosomal protein S6 |
chr9 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
38 |
150 |
25 |
25 |
0 |
RTF1 |
RTF1 |
Q92541 |
RNA polymerase-associated protein RTF1 homolog |
chr15 |
Not Cancer Driver |
No
|
1 |
biogrid |
83 |
568 |
67 |
67 |
0 |
S100P |
S100P |
P25815 |
Protein S100-P |
chr4 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
7 |
3 |
1 |
1 |
0 |
SCHIP1 |
SCHIP1 |
P0DPB3-4 |
Isoform SCHIP1-4 of Schwannomin-interacting protein 1 |
chr3 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
50 |
202 |
45 |
45 |
0 |
SEM1_ENST00000356686 |
SEM1 |
Q6ZVN7 |
Putative protein SEM1, isoform 2 |
chr7 |
Not Cancer Driver |
No
|
1 |
hippie |
2 |
52 |
1 |
1 |
0 |
SIAH2 |
SIAH2 |
O43255 |
E3 ubiquitin-protein ligase SIAH2 |
chr3 |
Not Cancer Driver |
No
|
1 |
hippie |
48 |
68 |
3 |
3 |
0 |
SMURF1 |
SMURF1 |
Q9HCE7 |
E3 ubiquitin-protein ligase SMURF1 |
chr7 |
Not Cancer Driver |
No
|
1 |
hippie |
89 |
256 |
31 |
31 |
0 |
SMYD2 |
SMYD2 |
Q9NRG4 |
N-lysine methyltransferase SMYD2 |
chr1 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
42 |
12 |
0 |
0 |
0 |
SNAI1 |
SNAI1 |
O95863 |
Zinc finger protein SNAI1 |
chr20 |
Not Cancer Driver |
No
|
1 |
hippie |
52 |
97 |
11 |
11 |
0 |
SNAPC1 |
SNAPC1 |
Q16533 |
snRNA-activating protein complex subunit 1 |
chr14 |
Not Cancer Driver |
No
|
1 |
biogrid |
36 |
158 |
16 |
16 |
0 |
SOD1 |
SOD1 |
P00441 |
Superoxide dismutase [Cu-Zn] |
chr21 |
Not Cancer Driver |
No
|
1 |
hippie |
16 |
93 |
9 |
9 |
79 |
SPRTN |
SPRTN |
Q9H040 |
DNA-dependent metalloprotease SPRTN |
chr1 |
Not Cancer Driver |
No
|
1 |
hippie |
73 |
252 |
38 |
38 |
1 |
SQSTM1 |
SQSTM1 |
Q13501 |
Sequestosome-1 |
chr5 |
Not Cancer Driver |
No
|
1 |
hippie |
54 |
267 |
32 |
32 |
30 |
SREBF2 |
SREBF2 |
Q12772 |
Sterol regulatory element-binding protein 2 |
chr22 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
124 |
357 |
43 |
43 |
0 |
SSBP1_ENST00000484178 |
SSBP1 |
Q04837 |
Single-stranded DNA-binding protein, mitochondrial |
chr7 |
Not Cancer Driver |
No
|
1 |
biogrid |
27 |
0 |
0 |
0 |
6 |
STK24 |
STK24 |
Q9Y6E0 |
Serine/threonine-protein kinase 24 |
chr13 |
Not Cancer Driver |
No
|
1 |
hippie |
67 |
118 |
16 |
16 |
0 |
STK25 |
STK25 |
O00506 |
Serine/threonine-protein kinase 25 |
chr2 |
Not Cancer Driver |
No
|
1 |
hippie |
42 |
170 |
15 |
15 |
0 |
STUB1 |
STUB1 |
Q9UNE7 |
E3 ubiquitin-protein ligase CHIP |
chr16 |
Not Cancer Driver |
No
|
2 |
hippie, biogrid |
35 |
112 |
14 |
14 |
12 |
SUMO2 |
SUMO2 |
P61956 |
Small ubiquitin-related modifier 2 |
chr17 |
Not Cancer Driver |
No
|
1 |
hippie |
9 |
69 |
6 |
6 |
0 |
TCF3 |
TCF3 |
P15923 |
Transcription factor E2-alpha |
chr19 |
Census |
Yes
|
1 |
hippie |
52 |
649 |
52 |
52 |
0 |
TCP11L1_ENST00000432887 |
TCP11L1 |
Q9NUJ3 |
T-complex protein 11-like protein 1 |
chr11 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
59 |
74 |
8 |
8 |
0 |
TERF1 |
TERF1 |
P54274 |
Telomeric repeat-binding factor 1 |
chr8 |
Not Cancer Driver |
No
|
1 |
hippie |
63 |
220 |
34 |
34 |
0 |
TERF2IP |
TERF2IP |
Q9NYB0 |
Telomeric repeat-binding factor 2-interacting protein 1 |
chr16 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
28 |
310 |
16 |
16 |
0 |
TGM2 |
TGM2 |
P21980 |
Protein-glutamine gamma-glutamyltransferase 2 |
chr20 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
123 |
107 |
26 |
26 |
0 |
THBS1 |
THBS1 |
P07996 |
Thrombospondin-1 |
chr15 |
Not Cancer Driver |
No
|
1 |
hippie |
188 |
320 |
58 |
58 |
0 |
TMEM129_ENST00000536901 |
TMEM129 |
A0AVI4 |
E3 ubiquitin-protein ligase TM129 |
chr4 |
Not Cancer Driver |
No
|
1 |
hippie |
15 |
8 |
1 |
1 |
0 |
TMEM31 |
TMEM31 |
Q5JXX7 |
Transmembrane protein 31 |
chrX |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
26 |
61 |
10 |
10 |
0 |
TMEM67 |
TMEM67 |
Q5HYA8 |
Meckelin |
chr8 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
120 |
11 |
0 |
0 |
37 |
TNFRSF21 |
TNFRSF21 |
O75509 |
Tumor necrosis factor receptor superfamily member 21 |
chr6 |
Not Cancer Driver |
No
|
1 |
hippie |
98 |
280 |
46 |
46 |
0 |
TNIP2 |
TNIP2 |
Q8NFZ5 |
TNFAIP3-interacting protein 2 |
chr4 |
Not Cancer Driver |
No
|
1 |
hippie |
43 |
316 |
36 |
36 |
0 |
TP53BP1_ENST00000263801 |
TP53BP1 |
Q12888 |
TP53-binding protein 1 |
chr15 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
227 |
1632 |
190 |
190 |
0 |
TP53_ENST00000445888 |
TP53 |
P04637 |
Cellular tumor antigen p53 |
chr17 |
Census, Compendium |
Yes
|
1 |
hippie |
2891 |
282 |
1466 |
1466 |
83 |
TPD52L2_ENST00000346249 |
TPD52L2 |
O43399 |
Tumor protein D54 |
chr20 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
25 |
180 |
22 |
22 |
0 |
TRAF6_ENST00000348124 |
TRAF6 |
Q9Y4K3 |
TNF receptor-associated factor 6 |
chr11 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
67 |
62 |
7 |
7 |
0 |
TRIM14 |
TRIM14 |
Q14142 |
Tripartite motif-containing protein 14 |
chr9 |
Not Cancer Driver |
No
|
1 |
hippie |
36 |
93 |
7 |
7 |
0 |
TRIM28 |
TRIM28 |
Q13263 |
Transcription intermediary factor 1-beta |
chr19 |
Not Cancer Driver |
No
|
1 |
hippie |
87 |
430 |
41 |
41 |
0 |
TRIM63 |
TRIM63 |
Q969Q1 |
E3 ubiquitin-protein ligase TRIM63 |
chr1 |
Not Cancer Driver |
No
|
1 |
hippie |
47 |
71 |
13 |
13 |
0 |
TXNIP |
TXNIP |
Q9H3M7 |
Thioredoxin-interacting protein |
chr1 |
Not Cancer Driver |
No
|
1 |
hippie |
61 |
77 |
14 |
14 |
0 |
TXNL1_ENST00000590954 |
TXNL1 |
O43396 |
Thioredoxin-like protein 1 |
chr18 |
Not Cancer Driver |
No
|
1 |
hippie |
41 |
89 |
4 |
4 |
0 |
UBA52_ENST00000595683 |
UBA52 |
P62987 |
Ubiquitin-60S ribosomal protein L40 |
chr19 |
Not Cancer Driver |
No
|
1 |
hippie |
19 |
45 |
8 |
8 |
0 |
UBAC1 |
UBAC1 |
Q9BSL1 |
Ubiquitin-associated domain-containing protein 1 |
chr9 |
Not Cancer Driver |
No
|
1 |
hippie |
38 |
241 |
23 |
23 |
0 |
UBB_ENST00000614404 |
UBB |
P0CG47 |
Polyubiquitin-B |
chr17 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
20 |
102 |
8 |
8 |
0 |
UBC |
UBC |
P0CG48 |
Polyubiquitin-C |
chr12 |
Not Cancer Driver |
No
|
5 |
intact |
97 |
312 |
53 |
53 |
0 |
UBD |
UBD |
O15205 |
Ubiquitin D |
chr6 |
Not Cancer Driver |
No
|
1 |
hippie |
31 |
8 |
1 |
1 |
0 |
UBE2C |
UBE2C |
O00762 |
Ubiquitin-conjugating enzyme E2 C |
chr20 |
Not Cancer Driver |
No
|
1 |
hippie |
13 |
40 |
0 |
0 |
0 |
UBE2M |
UBE2M |
P61081 |
NEDD8-conjugating enzyme Ubc12 |
chr19 |
Not Cancer Driver |
No
|
1 |
hippie |
30 |
32 |
6 |
6 |
0 |
UBE3A |
UBE3A |
Q05086 |
Ubiquitin-protein ligase E3A |
chr15 |
Not Cancer Driver |
No
|
3 |
intact, hippie, biogrid |
141 |
136 |
22 |
22 |
0 |
UBLCP1 |
UBLCP1 |
Q8WVY7 |
Ubiquitin-like domain-containing CTD phosphatase 1 |
chr5 |
Not Cancer Driver |
No
|
1 |
intact, hippie |
39 |
42 |
4 |
4 |
0 |
UBQLN1 |
UBQLN1 |
Q9UMX0 |
Ubiquilin-1 |
chr9 |
Not Cancer Driver |
No
|
1 |
hippie |
64 |
543 |
58 |
58 |
0 |
UBQLN2 |
UBQLN2 |
Q9UHD9 |
Ubiquilin-2 |
chrX |
Not Cancer Driver |
No
|
2 |
intact, hippie |
82 |
581 |
79 |
79 |
8 |
UBQLN4 |
UBQLN4 |
Q9NRR5 |
Ubiquilin-4 |
chr1 |
Not Cancer Driver |
No
|
1 |
hippie |
70 |
561 |
67 |
67 |
1 |
UBXN1_ENST00000301935 |
UBXN1 |
Q04323 |
UBX domain-containing protein 1 |
chr11 |
Not Cancer Driver |
No
|
1 |
hippie |
35 |
271 |
33 |
33 |
0 |
UCHL5 |
UCHL5 |
Q9Y5K5 |
Ubiquitin carboxyl-terminal hydrolase isozyme L5 |
chr1 |
Not Cancer Driver |
No
|
5 |
intact, hippie, biogrid |
33 |
41 |
7 |
7 |
0 |
UFL1 |
UFL1 |
O94874 |
E3 UFM1-protein ligase 1 |
chr6 |
Not Cancer Driver |
No
|
1 |
hippie |
109 |
141 |
24 |
24 |
0 |
USE1 |
USE1 |
Q9NZ43 |
Vesicle transport protein USE1 |
chr19 |
Not Cancer Driver |
No
|
1 |
biogrid |
31 |
101 |
19 |
19 |
0 |
USP14 |
USP14 |
P54578 |
Ubiquitin carboxyl-terminal hydrolase 14 |
chr18 |
Not Cancer Driver |
No
|
1 |
intact, hippie, biogrid |
59 |
86 |
6 |
6 |
0 |
USP15 |
USP15 |
Q9Y4E8 |
Ubiquitin carboxyl-terminal hydrolase 15 |
chr12 |
Not Cancer Driver |
No
|
1 |
hippie |
136 |
259 |
39 |
39 |
0 |
USP37_ENST00000454775 |
USP37 |
Q86T82 |
Ubiquitin carboxyl-terminal hydrolase 37 |
chr2 |
Not Cancer Driver |
No
|
1 |
hippie |
112 |
530 |
62 |
62 |
0 |
USP7 |
USP7 |
Q93009 |
Ubiquitin carboxyl-terminal hydrolase 7 |
chr16 |
Not Cancer Driver |
No
|
1 |
hippie |
170 |
215 |
45 |
45 |
0 |
VCP |
VCP |
P55072 |
Transitional endoplasmic reticulum ATPase |
chr9 |
Not Cancer Driver |
No
|
1 |
hippie |
88 |
186 |
16 |
16 |
16 |
VIRMA |
VIRMA |
Q69YN4 |
Protein virilizer homolog |
chr8 |
Not Cancer Driver |
No
|
1 |
hippie |
211 |
631 |
93 |
93 |
0 |
XPC |
XPC |
Q01831 |
DNA repair protein complementing XP-C cells |
chr3 |
Census, Compendium |
Yes
|
1 |
hippie |
88 |
479 |
48 |
48 |
2 |
XRCC6 |
XRCC6 |
P12956 |
X-ray repair cross-complementing protein 6 |
chr22 |
Not Cancer Driver |
No
|
1 |
hippie |
66 |
140 |
12 |
12 |
0 |
ZNF24 |
ZNF24 |
P17028 |
Zinc finger protein 24 |
chr18 |
Not Cancer Driver |
No
|
1 |
hippie, biogrid |
47 |
187 |
29 |
29 |
0 |